JP2020508112A5 - - Google Patents

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JP2020508112A5
JP2020508112A5 JP2019544631A JP2019544631A JP2020508112A5 JP 2020508112 A5 JP2020508112 A5 JP 2020508112A5 JP 2019544631 A JP2019544631 A JP 2019544631A JP 2019544631 A JP2019544631 A JP 2019544631A JP 2020508112 A5 JP2020508112 A5 JP 2020508112A5
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Prior art keywords
biological medium
field
electrodes
laser
vacuum head
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JP2019544631A
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JP2020508112A (ja
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Priority claimed from PCT/US2018/018596 external-priority patent/WO2018152460A1/en
Publication of JP2020508112A publication Critical patent/JP2020508112A/ja
Publication of JP2020508112A5 publication Critical patent/JP2020508112A5/ja
Priority to JP2022182281A priority Critical patent/JP2023009180A/ja
Priority to JP2024020280A priority patent/JP2024040432A/ja
Ceased legal-status Critical Current

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Claims (21)

  1. 組織治療を提供するための装置であって、前記装置は、
    場を発生させ、生物学的媒体の一部を通して前記場を印加するように構成される場発生器と、
    前記場発生器にDCを提供するように構成される直流(DC)電力供給源と、
    前記場の印加の間に前記生物学的媒体の前記一部にレーザ光を送達するように構成される光源と
    を備え
    前記装置は、前記レーザ光の送達に先立つ前記場の印加および/または前記レーザ光の送達の間の前記場の印加が、前記レーザ光の経路から離れるように前記一部の中で自由電子を移動させるように、構成される、装置。
  2. 前記場は、本質的に静的な場を含み、前記場発生器は、前記本質的に静的な場を前記生物学的媒体に印加し、前記生物学的媒体の前記一部の中での自由電子の移動を誘起するように構成され、
    前記生物学的媒体の前記一部への前記レーザ光の送達は、組織顔料粒子の光学破壊を提供する、請求項1に記載の装置。
  3. 前記場発生器は、複数の電極を備え、前記複数の電極は、前記複数の電極を横断して前記場を提供するように構成され、前記場は、電場を含む、請求項に記載の装置。
  4. 前記場発生器は、磁気コイルを備え、前記場は、磁場を含む、請求項に記載の装置。
  5. 前記光源は、少なくとも1Hzのパルス繰り返し数および0.5J/cm 〜20J/cm のフルエンスを伴うレーザ光を送達するように構成されるパルスレーザを含み、随意に、前記フルエンスは、3.5J/cm 〜9J/cm である、請求項に記載の装置。
  6. 前記生物学的媒体の表面に接触するように構成されるヘッドデバイスをさらに備え
    前記ヘッドデバイスは、前記場発生器を含み、
    前記ヘッドデバイスは、前記光源に物理的に結合される、請求項に記載の装置。
  7. 前記ヘッドデバイスは、真空ヘッドを備え、前記真空ヘッドは、真空源に接続され、前記生物学的媒体の前記一部に吸引を印加するように構成され、前記真空ヘッドは、前記吸引の印加の間に光が前記生物学的媒体の前記一部に到達することを可能にするように構成される、請求項に記載の装置。
  8. 静電場を提供するように構成されるエレクトレットをさらに備え、
    前記エレクトレットは前記静電場が生物学的媒体中に電場を誘起するように、前記生物学的媒体に対して位置付けられるようにさらに構成され、
    前記誘起された電場は、前記生物学的媒体の一部の中の自由電子に影響を与える、請求項に記載の装置。
  9. 前記エレクトレットは、透明である、請求項に記載の装置。
  10. レーザビームを前記生物学的媒体の前記一部に送達するように構成される治療用レーザシステムをさらに備え、
    前記エレクトレットは、前記エレクトレットを通した前記レーザビームの伝送を可能にするように構成され、
    前記治療用レーザシステムは前記エレクトレットを通して前記レーザビームを伝送することによって、前記レーザビームを前記生物学的媒体の前記一部に送達するようにさらに構成される、請求項に記載の装置。
  11. 組織治療を提供するための装置であって、前記装置は、
    直流(DC)電圧源と、
    複数の電極であって、前記複数の電極は、前記複数の電極を横断して電場を提供するように構成される、複数の電極と
    を備え、
    前記DC電圧源は、前記電極に電気的に接続され、
    前記電極のうちの第1のものは、生物学的媒体に接触するように構成される導電性表面を備え、前記電極のうちの第2のものは、前記生物学的媒体に電流を伝導しないように構成され、
    前記複数の電極は、自由電子が前記生物学的媒体の一部の中で影響を受けるように、前記電場を前記生物学的媒体の前記一部に印加するように構成される、装置。
  12. 真空源に接続されるように構成される真空ヘッドをさらに備え、
    前記複数の電極の一部は、前記真空ヘッド内に含有され、
    前記真空ヘッドは、吸引を前記生物学的媒体の前記一部に印加するように構成され、
    前記真空ヘッドは、吸引が印加されると、光が前記生物学的媒体の前記一部に到達することを可能にするように構成される、請求項11に記載の装置。
  13. 前記真空ヘッドは、使い捨てである、請求項12に記載の装置。
  14. 前記真空ヘッドは、窓を備え、前記窓を通して光が前記生物学的媒体の前記一部に到達することが可能である、請求項12に記載の装置。
  15. レーザビームを窓を通して前記生物学的媒体の前記一部に送達するように構成される治療用レーザシステムをさらに備え、
    前記レーザビームは、軸を有し、
    前記生物学的媒体の前記一部に印加される前記電場は、吸引が前記真空ヘッドによって前記生物学的媒体の前記一部に印加されるとき、前記レーザビームの前記軸に垂直である、請求項14に記載の装置。
  16. 磁気コイルをさらに備え、
    前記DC電圧源はDC電力を前記磁気コイルに提供するようにさらに構成され、
    前記磁気コイルは、そのように給電されると、前記生物学的媒体の前記一部の中で磁場を誘起するように構成される、請求項11に記載の装置。
  17. 前記装置は、レーザ光の送達に先立つ前記場の印加および/または前記レーザ光の送達の間の前記場の印加が、前記レーザ光の経路から離れるように前記生物学的媒体の前記一部の中で自由電子を移動させるように、構成される、請求項11に記載の装置。
  18. 前記電場は、負の静的な場を含む、請求項11に記載の装置。
  19. 入墨除去の非外科的システムであって、前記システムは、
    電場発生システムを備える場発生器であって、前記電場発生システムは、直流(DC)電力に基づく作動に応じて、生物学的媒体の一部を通して電場を印加するように構成される、場発生器と、
    光源であって、前記光源は、レーザ光を前記生物学的媒体の前記一部に送達するように構成される、光源と
    を含む、システム。
  20. 前記場発生器を作動させることに先立って、前記場発生器は、第1の場所において前記生物学的媒体に隣接して位置付けられるように構成され、
    前記レーザ光を送達することに先立って、前記光源は、前記レーザ光を前記一部に送達するために、前記生物学的媒体の前記一部に対して位置付けられるように構成される、請求項19に記載のシステム
  21. 記生物学的媒体の表面と接触するように設置されるように構成される真空ヘッドをさらに備え、
    負圧は、前記生物学的媒体の少なくとも前記一部を安定化させるために、前記真空ヘッドに印加され前記生物学的媒体の少なくとも前記一部は、前記一部への前記レーザ光の送達の間に安定化される、請求項19に記載のシステム
JP2019544631A 2017-02-19 2018-02-19 生物学的媒体中の選択的レーザ誘起光学破壊 Ceased JP2020508112A (ja)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2022182281A JP2023009180A (ja) 2017-02-19 2022-11-15 生物学的媒体中の選択的レーザ誘起光学破壊
JP2024020280A JP2024040432A (ja) 2017-02-19 2024-02-14 生物学的媒体中の選択的レーザ誘起光学破壊

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US201762460867P 2017-02-19 2017-02-19
US62/460,867 2017-02-19
PCT/US2018/018596 WO2018152460A1 (en) 2017-02-19 2018-02-19 Selective laser induced optical breakdown in biological medium

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JP2020508112A5 true JP2020508112A5 (ja) 2021-04-01

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JP2022182281A Pending JP2023009180A (ja) 2017-02-19 2022-11-15 生物学的媒体中の選択的レーザ誘起光学破壊
JP2024020280A Pending JP2024040432A (ja) 2017-02-19 2024-02-14 生物学的媒体中の選択的レーザ誘起光学破壊

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US (2) US11813477B2 (ja)
EP (1) EP3582686A4 (ja)
JP (3) JP2020508112A (ja)
KR (2) KR20230144665A (ja)
CN (1) CN110536634A (ja)
AU (2) AU2018221251B2 (ja)
BR (1) BR112019017264A2 (ja)
CA (1) CA3053796A1 (ja)
WO (1) WO2018152460A1 (ja)

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