JP2020096925A - 置換心臓弁装置および方法 - Google Patents
置換心臓弁装置および方法 Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
- A61F2/2412—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body with soft flexible valve members, e.g. tissue valves shaped like natural valves
- A61F2/2418—Scaffolds therefor, e.g. support stents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
- A61F2/2409—Support rings therefor, e.g. for connecting valves to tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
- A61F2/2412—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body with soft flexible valve members, e.g. tissue valves shaped like natural valves
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
- A61F2/2427—Devices for manipulating or deploying heart valves during implantation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
- A61F2/2427—Devices for manipulating or deploying heart valves during implantation
- A61F2/243—Deployment by mechanical expansion
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
- A61F2/2427—Devices for manipulating or deploying heart valves during implantation
- A61F2/2436—Deployment by retracting a sheath
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2210/00—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2210/0014—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof using shape memory or superelastic materials, e.g. nitinol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2210/00—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2210/0076—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof multilayered, e.g. laminated structures
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2230/00—Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2230/0063—Three-dimensional shapes
- A61F2230/0069—Three-dimensional shapes cylindrical
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2230/00—Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2230/0063—Three-dimensional shapes
- A61F2230/0091—Three-dimensional shapes helically-coiled or spirally-coiled, i.e. having a 2-D spiral cross-section
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2250/0058—Additional features; Implant or prostheses properties not otherwise provided for
- A61F2250/006—Additional features; Implant or prostheses properties not otherwise provided for modular
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2250/0058—Additional features; Implant or prostheses properties not otherwise provided for
- A61F2250/006—Additional features; Implant or prostheses properties not otherwise provided for modular
- A61F2250/0063—Nested prosthetic parts
Abstract
Description
本願は、2013年8月14日に出願された(係属中)米国特許仮出願第61/865,657号、2014年2月20日に出願された(係属中)米国特許仮出願第61/942,300号、および2014年2月21日に出願された(係属中)米国特許仮出願第61/943,125号の優先権を主張するものである。これらの仮出願の開示は、ここに参照により本明細書に組み込まれる。
心臓弁プロテーゼ(60)をドッキングするためのシステムであって、
天然心臓弁(16)に移植されるように構成されたらせん状アンカー(12)であって、当該らせん状アンカー(12)のコイル部分が心臓弁輪の上方および/または下方に配置されるように調整された状態で前記心臓弁プロテーゼ(60)を支持するように構成された複数のコイル(22)を備えるように形成されたらせん状アンカー(12)と、
可撓性を有する外方チューブ(32)であって、前記らせん状アンカー(12)の複数の前記コイル(22)を当該外方チューブ(32)内に保持し、アセンブリを形成するように構成された外方チューブ(32)と、
前記アセンブリを搬送する送達ツール(30)であって、前記アセンブリを前記心臓弁輪の上方および/または下方に位置決めするために天然心臓弁(16)の近くで回転可能な送達ツール(30)と、
を含んでなり、
前記アセンブリが前記心臓弁輪の上方および/または下方に位置決めされた後に、前記外方チューブ(32)が、前記らせん状アンカー(12)の複数の前記コイル(22)から取り除かれるように構成され、
前記天然心臓弁に送達され得る拡張可能心臓弁プロテーゼ(60)であって、前記天然心臓弁において複数の前記コイル(22)の内部で拡張され得る拡張可能心臓弁プロテーゼ(60)をさらに含んでなることを特徴とするシステム。
[第2項]
前記アセンブリが前記心臓弁輪の上方および/または下方に位置決めされた後に、前記外方チューブ(32)が、前記らせん状アンカー(12)の複数の前記コイル(22)からスライドして外れるように調整された低摩擦材料から形成されていることを特徴とする第1項に記載のシステム。
[第3項]
前記外方チューブ(32)が、縫合糸(34、36)により前記送達ツール(30)に固定されていることを特徴とする第1項に記載のシステム。
[第4項]
前記送達ツール(30)が複数のコイル(31)と共に形成され、当該システムが、前記送達ツール(30)の前記コイル(31)の遠位端部(38、70)をさらに含み、前記外方チューブ(32)が、前記遠位端部(38、70)にさらに固定されていることを特徴とする第1項に記載のシステム。
[第5項]
前記遠位端部(70)が、ブレット形状またはテーパ形状をさらに含むことを特徴とする第4項に記載のシステム。
[第6項]
前記遠位端部(70)が弾性要素をさらに含み、前記外方チューブ(32)および前記送達ツール(30)の遠位端部が前記弾性要素(70)に固定されていることを特徴とする第5項に記載のシステム。
[第7項]
前記心臓弁プロテーゼ(60)が、前記心臓弁プロテーゼ(60)の流出端部の端部エッジをカバーするシールを含むことを特徴とする第1項に記載のシステム。
[第8項]
プッシャ要素をさらに含み、前記アセンブリが前記心臓弁輪の上方および/または下方に位置決めされた後に、前記プッシャ要素で前記アンカー(12)を定位置に保持し、前記外方チューブ(32)を前記アンカー(12)から引き離しつつ、前記外方チューブ(32)が、前記らせん状アンカー(12)の複数の前記コイル(22)から取り除かれるように構成されていることを特徴とする第1項に記載のシステム。
[第9項]
前記送達ツール(30)は、前記天然心臓弁の交連を貫通する前記アセンブリを、前記心臓弁輪の上方および/または下方に位置決めされた前記アセンブリの位置内に送達するように適用されていることを特徴とする第1項に記載のシステム。
[第10項]
複数の前記コイル(22)が少なくとも3つのコイルを含むことを特徴とする第1項に記載のシステム。
[第11項]
複数の前記コイル(22)と前記心臓弁プロテーゼ(60)とが、前記天然心臓弁に移植された時、複数の前記コイル(22)と前記心臓弁プロテーゼ(60)との間で、前記天然心臓弁の弁葉を捕獲するように構成されていることを特徴とする第1項に記載のシステム。
[第12項]
システムであって、
天然心臓弁(16)に移植されるように構成されたアンカー(12)であって、当該アンカー(12)のコイル部分が心臓弁輪の上方および/または下方に配置されるように調整された状態で前記心臓弁プロテーゼ(60)を支持するように構成された複数のコイル(22)を備えるように形成されたアンカー(12)と、
可撓性を有する外方チューブ(32)であって、前記アンカー(12)の複数の前記コイル(22)を当該外方チューブ(32)内に保持し、アセンブリを形成するように構成された外方チューブ(32)と、
前記アセンブリを搬送する送達ツール(30)であって、前記アセンブリを前記心臓弁輪の上方および/または下方に位置決めすることができる送達ツール(30)と、
プッシャ要素と、
を含んでなり、
前記アセンブリが前記心臓弁輪の上方および/または下方に位置決めされた後に、前記プッシャ要素で前記アンカー(12)を定位置に保持し、前記外方チューブ(32)を前記アンカー(12)から引き離しつつ、前記外方チューブ(32)が、前記アンカー(12)の複数の前記コイル(22)から取り除かれるように構成されていることを特徴とするシステム。
[第13項]
前記天然心臓弁に送達され得る拡張可能心臓弁プロテーゼ(60)であって、前記天然心臓弁において複数の前記コイル(22)の内部で拡張され得る拡張可能心臓弁プロテーゼ(60)をさらに含むことを特徴とする第12項に記載のシステム。
[第14項]
前記心臓弁プロテーゼ(60)が、前記心臓弁プロテーゼ(60)の流出端部の端部エッジをカバーするシールを含むことを特徴とする第13項に記載のシステム。
[第15項]
複数の前記コイル(22)と前記心臓弁プロテーゼ(60)とが、前記天然心臓弁に移植された時、複数の前記コイル(22)と前記心臓弁プロテーゼ(60)との間で、前記天然心臓弁の弁葉を捕獲するように構成されていることを特徴とする第13項に記載のシステム。
[第16項]
前記送達ツール(30)が、複数の巻線を含むことを特徴とする第12項に記載のシステム。
[第17項]
前記アセンブリが、縫合糸により前記送達ツールに固定されていることを特徴とする第12項に記載のシステム。
[第18項]
前記送達ツール(30)は、前記天然心臓弁の交連を貫通する前記アセンブリを、前記心臓弁輪の上方および/または下方に位置決めされた前記アセンブリの位置内に送達するように適用されていることを特徴とする第12項に記載のシステム。
[第19項]
複数の前記コイル(22)が少なくとも3つのコイルを含むことを特徴とする第12項に記載のシステム。
[第20項]
複数の前記コイル(22)が少なくとも4つのコイルを含むことを特徴とする第12項に記載のシステム。
[第21項]
システムであって、
天然心臓弁(16)に移植されるように構成されたアンカー(12)であって、当該アンカー(12)のコイル部分が心臓弁輪の上方および/または下方に配置されるように調整された状態で前記心臓弁プロテーゼ(60)を支持するように構成された少なくとも3つのコイル(22)を備えるように形成されたアンカー(12)と、
可撓性を有する外方チューブ(32)であって、前記アンカー(12)の少なくとも3つの前記コイル(22)を当該外方チューブ(32)内に保持し、アセンブリを形成するように構成された外方チューブ(32)と、
前記アセンブリを搬送する送達ツール(30)であって、前記アセンブリを前記心臓弁輪の上方および/または下方に位置決めすることができる送達ツール(30)と、
を含んでなり、
前記アセンブリが前記心臓弁輪の上方および/または下方に位置決めされた後に、前記外方チューブ(32)が、前記アンカー(12)の少なくとも3つの前記コイル(22)から取り除かれるように構成されていることを特徴とするシステム。
[第22項]
前記天然心臓弁に送達され得る伸展性心臓弁プロテーゼ(60)であって、前記天然心臓弁において少なくとも3つの前記コイル(22)の内部で拡張され得る伸展性心臓弁プロテーゼ(60)をさらに含むことを特徴とする第21項に記載のシステム。
[第23項]
前記心臓弁プロテーゼ(60)が、前記心臓弁プロテーゼ(60)の流出端部の端部エッジをカバーするシールを含むことを特徴とする第22項に記載のシステム。
[第24項]
少なくとも3つの前記コイル(22)と前記心臓弁プロテーゼ(60)とが、前記天然心臓弁に移植された時、複数の前記コイル(22)と前記心臓弁プロテーゼ(60)との間で、前記天然心臓弁の弁葉を捕獲するように構成されていることを特徴とする第22項に記載のシステム。
[第25項]
プッシャ要素をさらに含み、前記アセンブリが前記心臓弁輪に位置決めされた後に、前記プッシャ要素で前記アンカー(12)を定位置に保持し、前記外方チューブ(32)を前記アンカー(12)から引き離しつつ、前記外方チューブ(32)が、前記らせん状アンカー(12)の少なくとも3つの前記コイル(22)から取り除かれるように構成されていることを特徴とする第21項に記載のシステム。
[第26項]
前記送達ツール(30)が、複数の巻線を含むことを特徴とする第21項に記載のシステム。
[第27項]
前記アセンブリが、縫合糸により前記送達ツールに固定されていることを特徴とする第21項に記載のシステム。
[第28項]
少なくとも3つの前記コイル(22)が少なくとも4つのコイルを含むことを特徴とする第21項に記載のシステム。
[第29項]
前記送達ツール(30)は、前記天然心臓弁の交連を貫通する前記アセンブリを、前記心臓弁輪の上方および/または下方に位置決めされた前記アセンブリの位置内に送達するように適用されていることを特徴とする第21項に記載のシステム。
10a 遠位先端部
12 らせん状アンカー
12a 内部ワイヤコイル
12b 外部コーティング
12c 軟質先端部
14 交連
16 天然僧帽弁
18 天然弁葉、人工弁葉
20 天然弁葉、人工弁葉
22 巻線またはコイル
24 索、腱索
26 ワイヤ
30 らせん状送達ツール
31 コイル
32 外方チューブ
34 縫合糸
36 縫合糸
38 ループ
40 心臓
42 メス
44 鉗子
50 押し棒
52 カップ状端部
60 置換心臓弁
62 弁葉
64 弁葉
66 本体
70 ブレット形状ヘッド
72 スリット
80 緩衝体構造体
82 発泡体
84 封止層
86 開ステント構造体
90 生体組織シール
91 間隙
92 繊維層
100 送達シース
101 送達シース、送達カテーテル
102 右心房
104 心房中隔
106 左心房
108 左心室
110 アーム
120 ループ
126 天然僧帽弁輪
140 らせん状アンカー送達チューブ、チューブ状アーム
152 面
160 繊維カバー
162 発泡層、発泡体
170 組織束ねデバイス
172 一時的リングまたはループ
180 上方らせん状アンカー部分、心房らせん状アンカー部分
182 下方らせん状アンカー部分、心室らせん状アンカー部分
184 圧着接合部
200 間隙
202 弁輪シール
210 バルーンカテーテル
Claims (1)
- 心臓弁プロテーゼをドッキングするためのシステムであって、本願明細書に記載された特徴を有するシステム。
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