US3755823A - Flexible stent for heart valve - Google Patents

Flexible stent for heart valve Download PDF

Info

Publication number
US3755823A
US3755823A US3755823DA US3755823A US 3755823 A US3755823 A US 3755823A US 3755823D A US3755823D A US 3755823DA US 3755823 A US3755823 A US 3755823A
Authority
US
Grant status
Grant
Patent type
Prior art keywords
framework
recited
device
arms
heart valve
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
Inventor
W Hancock
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
EXTRACORPOREAL MEDICAL SPECIALTIES Inc A CORP
Medtronic Inc
Original Assignee
Hancock Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Grant date

Links

Images

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/24Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices
    • A61F2/2412Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices with soft flexible valve members, e.g. tissue valves shaped like natural valves
    • A61F2/2418Scaffolds therefor, e.g. support stents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/24Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices
    • A61F2/2409Support rings therefor, e.g. for connecting valves to tissue
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S623/00Prosthesis, i.e. artificial body members, parts thereof, or aids and accessories therefor
    • Y10S623/90Stent for heart valve

Abstract

An arrangement for heart valves that includes a stent having apexes interconnected by arms, the apexes being deflectable inwardly upon hemodynamic loading of the heart valve for reducing the stress in the valve tissue, the stent being covered by a cloth sleeve which may have an integral bead or flap for attachment to the heart, padding being provided beneath portions of the sleeve for protection, and a reinforcing ring extending around the assembly over the marginal portions of the heart valve, with sutures extending through the reinforcing ring and tissue of the heart valve for forming an attachment to the stent.

Description

tilled States atet [1 1 llanenelr 1 se ta, 197a FLEXIBLE STENT FOR HEART VALVE [75] Inventor: Warren 11). ll-lancoelt, Santa Ana,

[21] Appl. No.: 136,832

[52] US. Cl. 3/1, 3/D1G. 3 {51] lint. Cl. ..A61i 1/22 [58] Field of Search 3/1, D10. 3

[56] References Cited UNITED STATES PATENTS 3,570,014 3/1971 Hancock 3/1 3,197,788 8/1965 Segger 3/1 OTHER PUBLICATIONS Heart Valve Replacement With Reinforced Aortic Heterografts by M. l. Fonescu et al. The Journal of Thoracic & Cardiovascular Surgery, Vol. 56, No. 3, Sept. 1968, pp. 333-348.

Clinical Experience With Supported Homograft Heart Valve For Mitral and Aortic Valve Replacement by S. Sugie et al., The Journal of Thoracic & Cardiovascular Surgery, Vol. 57, No. 4. Apr. 1969, pp. 455-462.

Pig Aortic Valve as a Replacement for Mitral Valve in the Dog," by W. A. Reed et al., The Journal of Thoracic and Cardiovascular Surgery, Vol. 57, No. 5, May 1969, pp. 663-667.

Primary Examiner-Richard A. Gaudet Assistant Examiner-Ronald L. Frinks Attorney-Gausewitz, Carr & Rothenberg 5 7 ABSTRACT An arrangement for heart valves that includes a stent having apexes interconnected by arms, the apexes being deflectable inwardly upon hemodynamic loading of the heart valve for reducing the stress in the valve tissue, the stent being covered by a cloth sleeve which may have an integral bead or flap llor attachment to the heart, padding being provided beneath portions of the sleeve for protection, and a reinforcing ring extending around the assembly over the marginal portions of the heart valve, with sutures extending through the reinforcing ring and tissue of the heart valve for forming an attachment to the stem.

27 Claims, 12 Drawing Figures FLEXIBLE STENT FOR HEART VALVE BACKGROUND OF THE INVENTION- l. Field of the Invention This invention relates to a supporting framework, or stent, for a natural or synthetic heart valve.

2. Description of Prior Art It has been established that a stent is a useful arrangement for supporting a natural or synthetic heart valve for implantation in the human heart. The design shown in US. Pat. No. 3,570,014 offers advantages in properly supporting the valve and permitting its advance preparation for storage until the requirement for use arises. There has remained, however, room for improvement, particularly in assuring the reliability of the valve and its proper functioning over a long period of time. Malfunctioning of the valve may be caused by overstressing the valve tissue by the hemodynamic pressure imposed upon it when in use. Further areas of continued problems involve the fixing of the valve in the heart so as to provide a bed for ingrowth or attachment of tissue and a hemodynamic seal while avoiding clotting.

SUMMARY OF THE INVENTION The present invention provides an improved arrangement for supporting a natural or synthetic heart valve in which the reliability of the valve is significantly improved. The invention contemplates the use of a stent which may bear a resemblance inappearance to that of the aforementioned US. Pat. No. 3,570,014. It includes three spaced apexes to support the valve commissures, with arms interconnecting the apexes. However, unlike the stent of that patent and other previous designs, the stent of the present invention is resilient. This allows deflection of the three apexes of the stent when the valve is subject to hemodynamic pressure during diastole. As the apexes are resiliently bent inwardly toward the axis of the stent, the stress in the tissue of the heart valve is correspondingly reduced. The result is a major improvement in the reliability of the valve, with an attendant reduction in danger to the life of the patient. The stent returns to its normal full diameter when the pressure is relieved, so that there is no undue restriction when the valve is in the open position.

,The stent is arranged so that the arms remote from the apexes act as torsion bars as the deflection takes place, while the apexes themselves experience little distortion. Various arrangements may be included to stiffen the bars as may be required to obtain the proper degree of resiliency in the stent. The stiffening arrangements may include additional elements interconnecting the upper and lower bars of the stent.

A noncorrosive metal, such as stainless steel, may be used in constructing the stent, or it may be made of plastic. In either event, it is preferable that it be possible to deflect the arms permanently in order to vary the lateral dimensions of the stent so that it can be adjusted to fit a particular heart valve to be applied to it. This may be accomplished by exceeding the yield point of the metal stent, or through the use of heat or solvents in bending the plastic. In either event, however, the stent retains its resilience after the adjustment.

For a plastic stent, a reinforcing ring may be provided at the exterior of the end of the stent remote from the apexes, the ring being fitted loosely in a notch having a frustoconical inner .wall which. assures that the ring does not interfere with the flexing of the stent from the pressures on the heart valve.

Improved means, also may be included for more readily attaching the tissue to the stent and providing a matrix for ingrowth and subsequent fixation of the donor valve by the host tissue. This may include a cloth sleeve around the stent entirely covering it, together with an annular ring of cloth or sponge on the exterior of the unit at the end of the apexes extending over the marginal edge of the heart valve. The sutures for attaching the heart valve to the stent pass through the cloth ring as well, which reinforces the loops of the su tures so that they do not tend to cut through the tissue of the valve. Felt packing is included at apexes beneath the cloth sleeve to protect the cloth and sutures from abrading through contact with the stent.

The cloth sleeve around the stent may be provided with a bead intermediate the upper and lower arms, which also facilitates attachment to the heart and the ingrowth of tissue. When used in the mitral position, there is a projecting flat ring of cloth provided at the end of the stent opposite the apexes. This provides a means for suturing the valve assembly in the heart, resulting in a hemodynamic seal and a suitable bed over which tissue can be affixed or ingrown upon the grafting of the heart valve assembly.

BRIEF DESCRIPTION OF THE DRAWINGS:

FIG. I is a perspective view, partially broken away, illustrating a heart valve mounted on a stent in accordance with this invention;

FIG. 2 is an enlarged perspective view of the stent;

FIG. 3 is a side elevational view of the stent, illustrating the manner in which the stent deflects under load; FIG. 4 is a top plan view of the arrangement of FIG.

FIG. 5 is an enlarged fragmentary perspective view showing the attachment of the heart valve and cloth el ements to the stent;

FIG. 6 is a perspective view of a stent having additional members for controlling the deflection of the upper arms;

FIG. 7 is a perspective view of a stent having a different arrangement of the members to control the deflection of the upper arms;

FIG. 8 is a perspective view of a modified form of the stent also controlling the deflection of the upper arms;

FIG. 9 is an enlarged-fragmentary sectional view illustrating the arrangement for reinforcing the base of the stent when made from plastic;

FIG. 10 is a view similar to FIG. 5, but with a different arrangement of the cloth covering elements;

FIG. 11 is a view similar to FIGS. 5 and 110, but with the addition of a flap at the base of the stent for attachment to the heart; and

FIG. I2 is a perspective view of a stent of a different configuration.

DESCRIPTION OF THE PREFERRED EMBODIMENTS The stent 10 illustrated in FIGS. 1-4 is of a basic shape for use in the aortic, mitral, tricuspid or pulmonary location. The stent is an annular framework, circular in plan, made of a material which is both noncorrosive and resilient. Suitably, it may be constructed of a stainless steel, such as that marketed under the 3 trademark Elgiloy" by Elgiloy Company, 853 Dundee Ave, Elgin, 111. 60120. A resilient plastic, such as polypropylene, also may be used for the stent 10.

The stent includes three apical portions 11, 12 and 13 at one end of the annular framework, which are of generally oval shape so that they present rounded upper surfaces. Openings 14, 15 and 16 may be provided through the apical portions 11, 12 and 13. The apical portions 11, 12 and 13 are for supporting the commissures of a heart valve 18, which may be from a human or from an animal. Particularly when the stent is intended to receive an animal valve, the apical portions are not distributed equally around the perimeter of the stent 10. In the example shown, there is equal angular spacing between the apical portions 11 and 12 and between the apexes 11 and 13. However, the spacing between the apical portions 12 and 13 is approximately 17-33 percent under the spacing of the other apexes, preferably around -25 percent less. This is in order that the stent will conform to the spacing of the commissures of the valve 18 to be applied to it, which for animals is very close to this proportioning. Alternative spacing of the apexes is such that, if one space between adjacent apexes is a reference, a second is around 4-10 percent less than the reference space, and the third is about l7-33 percent less than the reference space.

Extending between the lower portions of the apical parts 11, 12 and 13 of the stent 10 are support arms 19, 20 and 21. These arms are scalloped, being curved away from the apical portions 11, 12 and 13 so that they are concave toward the end of the stent where the apexes are located. lmmediately beneath the apexes 11, 12 and 13 are short depending posts 22, 23 and 24, respectively, which are approximately parallel to the axis of the stent 10. Lower support arms 25, 26 and 27 interconnect the bottom ends of the posts 22, 23 and 24. The arms 25, 26 and 27 may fall substantially in a radial plane through the stent, collectively forming a ring, or they may be scalloped generally as are the arms 19, 20 and 21. However, when scalloped, the lower arms 25, 26 and 27 are not scalloped as deeply as are the upper arms. The lower arms 25, 26 and 27 are substantially the same distance from the axis of the stent as are the upper arms 19, 20 and 21.

Prior to attaching the valve 18 to the stent 10, a felt packing or jacket 28 is applied around each of the apexes 11, 12 and 13, extending downwardly also to encompass the support posts 22, 23 and 24 and the immediately adjacent portions of the lower arms 25, 26 and 27. The felt jackets 28 cover both the inner and outer surfaces of the stent. After this, a sleeve 29, which may be of woven material or felt, or of sponge, is applied to the stent 10. The cloth sleeve 29 is annular and contoured so that it fits over the apical portions 1 1, 12 and 13 and the felt packing 28, providing inner and outer layers along the inner and outer surfaces of the stent. The outer layer of the cloth sleeve 29 is stitched together around the perimeter of the stent to provide a bead 30. A ring 31 of felt or sponge may be received within the bead 30. The bead 30 and ring 31 provide a location for suturing when the valve is grafted in the heart, enabling a hemodynamic seal to be obtained.

After applying the cloth sleeve 29 to the stent 10, the valve 18 is positioned on the stent, with the valve commissures at the apexes 11, 12 and 13, while the margins of the cusps conform to the scalloped configuration of the support arms 19, 20 and 21. The presence of the various apexes and support arms assures that there is a portion of the stent conforming to the shape of the valve 18 available for secure attachment of all peripheral parts of the valve. The arcuate upper configuration of the apexes ll, 12 and 13 allows angular latitude in the positioning of the valve commissures. There are some dimensional differences among all natural valves, so that the spacing of the commissures may vary to a degree. With the upper portions of the apexes 11, 12 and 13 being arcuate, valves of different proportions may be accommodated and allowed to assume their natural contour while still being afforded ready and appropriate locations for attachment.

While being made of resilient material, the stent 10 may be given a permanent deflection, which is important in adapting the stent to conform to the contour of the particular heart valve being applied to it. The permanent deflection for a metal stent is achieved by manually deforming the arms 19, 20 and 21 beyond the yield point, while, for plastic stents, the application of heat or solvents may be necessary. Because of the sealloped configuration, bending of the support arms 19, 20 and 21 upwardly as the stent is shown causes an increase in the effective diameter of the stent. This is indicated in phantom in the left-hand portion of FIG. 3. Conversely, downward deflection of the support arms reduces the stent diameter. Permanent deflection of the arms 19, 20 and 21, therefore, allows the shape of the stent to be adjusted as needed. The resilience of the stent 10, however, is retained, irrespective of whether or not the arms 19, 20 and 21 are given a permanent deflection.

After the valve 18 has been applied to the stent 10, an additional annular reinforcing ring of cloth or sponge 33 is applied to the scalloped end of the stent 10, extending entirely around the perimeter of the stent. The outer margin of the ring 33 is tucked under the upper edge of the outer layer of the sleeve 29.

Sutures 34extend through the cloth ring 33, the edge of the outer layer of the sleeve 29 and the tissue of the valve 18, holding the assembly on the stent 10. The cloth ring 33 acts as a reinforcement for the suture line, distributing the load on the sutures. Without the cloth ring 33, there is some tendency for the loops of the sutures to pull through the tissue of the valve 18. However, the loops of the sutures 34 bear against the reinforcing ring 33 and will not cut the valve tissue.

The felt packing around the apexes 11, 12 and 13 provides a soft bed and padding that protects the sutures and the cloth 29 as well. Otherwise, there can be some abrasion of the sutures and the cloth on the relatively hard stent surface.

This completes the preparation of the heart valve, which may be stored at this point, ready for implantation. With the stent 10 being entirely covered by cloth, there is no exposure of the metal or plastic of the stent in the portions of the heart where clotting is a problem. Only tissue is exposed in the critical areas, so any tendency to clot is minimized.

An important advantage is realized from the resilience of the stent 10. Because of this, the stent 10 can deflect in response to hemodynamic pressure on the valve 18 during diastole after grafting in the heart of a patient. This, in turn, significantly reduces the tensile stress in the valve commissures, as a result of which the valve is more reliable and the risk to the patient is minimized. The nature of the deflection experienced by the stent is indicated in phantom in the right-hand portion of FIG. 3, as well as being shown in FIG. 4. The apexes ll, 12 and 13 are deflected inwardly by the forces imposed on the stent, pivoting about their lower portions as the movement takes place. During this deflection, the lower support arms 25, 26 and 27 act as torsion bars, twisting to allow the deflection of the apexes to occur. As the lower arms twist and the apexes bend inwardly, the upper arms also experience deflection. The apexes themselves are relatively rigid so that they do not bend appreciably, with the support arms being proportioned so that they will experience practically all of the distortion which takes place. The inward deflection of the apexes Ill, I2 and 13 reduces their spacing from the central axis of the stent, giving the stent a shape such that less tensile stress is imposed on the valve cusps. This is because the supports for the valve cusps are moved closer together by the deflection, which can be shown mathematically to result in reduced loading on the cusps. With the apexes II, 12 and 13 deflected inwardly, the cusps can assume a more natural and relaxed position during diastole. Also, energy is absorbed in deflecting the apexes, resulting in a damping effect that reduces the tensile stress in the valve tissue. While relieving the stress in the valve 18, the resilience of the stent also allows the apexes to return to their normal positions when the pressure is relieved. Consequently, the apexes do not remain in their inward positions where they extend into the valve passageway, and the valve can assume a full-open position without imposing an obstruction to the flow through it.

Experiments have established that, if the apexes are permitted to deflect approximately two millimeters in an average size human valve, the tensile stress in the commissures of the valve at the margin of attachment is reduced by approximately percent compared with that experienced on a rigid stent. This is a significant factor in assuring the proper functioning of the valve over a long period of time. Of course, the stent must be proportioned so that the proper amount of deflection will occur under the hemodynamic pressure exerted, which typically is around 2.3 psi.

The stent may be modified as indicated in FIG. 6 by the inclusion of a pair of diagonal bars 36 and 37 posi tioned with one on either side of each of the support posts 22, 23 and 241. These diagonal bars stiffen the upper arms 19, 2t) and 21 for controlling their deflection during preparation of the stent. This is to avoid bending the arms when the cloth sleeve 29 is attached so that the upper and lower arms are not brought into interengagement.

The stent of FIG. 7 is similar to that of FIGS. 1-4, but with the addition of intermediate posts 38, 39 and 40 between the upper arms I19, 20 and 2K and the lower arms 25, 26 and 27, respectively. The intermediate posts 38, 39 and 60 connect at the centers of the upper arms, stiffening them when it is desired to reduce the amount of deflection permitted.

In the stent 42 of FIG. 8, the straight posts beneath the apical portions are eliminated. Instead, the stent is provided with diagonal bars 43 and 44 beneath each of the apexes 45, 46 and 47. The latter elements are integral with the upper arms 48, 49 and 50, and open at their bottom ends because of the absence of the vertical posts beneath them. The diagonal posts 43 and 44 not only connect the upper arms 48, 49 and 50 with the lower arms 51, 52 and 53, but also serve to control the deflection of the upper arms.

FIG. 9 illustrates a fragmentary section of a plastic stent provided with an annular recess at its lower corner, which receives a metal reinforcing ring 55. The recess is defined by a radial upper wall 56 and a frustoconical inner wall 57, which tapers toward the end of the stent remote from the apexes. The ring 55, fitting loosely in the recess in the bottom end of the stent, stiffens and reinforces the plastic stent at that location. The surface 57 is tapered so that there will be no interference to inward deflection of the post 58 when the stent deflects under load. Therefore, the ring 55 will not interfere with full flexing of the stent. It will, however, keep the adjacent portion of the stent in a circular shape when the deflection takes place, so that the stent does not become unduly distorted.

The arrangement of FIG. 10 is similar to that of FIG. 5, but illustrates a variation in the attachment of the reinforcing ring at the scalloped end of the stent. Here, the annular member 60 of cloth or sponge extends over the upper edge of the cloth sleeve 29, rather than being tucked under the outer layer of the sleeve 29. The

edges of the reinforcing ring 60 are doubled under so that the ring 60 is in two layers with no exposed edges. Again, the elements attached to the stent 10 are held in place by sutures. The overlapping of the annular ring 60 over the outside layer of the sleeve 29 provides the assembly with a smoother and neater appearance.

Another variation is shown in FIG. 11 in which the cloth sleeve 6ll is similar to the cloth sleeve 29 described above. In addition, however, the sleeve 61 is provided with a flat, doubled-over, annular extension or flap 62 around the exterior of the stent adjacent the lower arms 25, 26 and 27. The cloth extension 62 provides a hernodynamic seal when grafted in the heart, as well as a suitable bed over which tissuecan be affixed or ingrown. This version is for use in the mitral position. No rigid reinforcement is included with the annular element 62, although felt or sponge may be provided between its layers.

The stent 64 of FIG. 12 preferably is made of plastic for full flexibility of its apexes 65, 66 and 67. The base ring 68 serves as the means to connect the apexes, as well as acting as a torsion bar and annular stiffener. Cloth maybe used to cover the stent 66, generally as described above, and the heart valve 16 may be sutured to the cloth when mounted on the stent. Instead of an animal or human heart valve, however, other tissue, such as fascia lata or pericardium, may be affixed to the stent to create valve cusps. For such purposes, the apexes 65, 66 and 67 may be equally spaced. A stiffener ring 55 may be employed with the stent 64 to reinforce the base ring 66.

The foregoing detailed description is to be clearly understood as given by way of illustration and example only, the spirit and scope of this invention being limited solely by the appended claims.

What is claimed is:

l. A stent for a heart valve comprising a framework of annular configuration,

said framework including spaced apical portions extending around the longitudinal axis thereof and arms interconnecting said apical portions, for thereby providing an attachment for the commissures and cusps of a heart valve,

said framework including means for permitting substantial resilient deflection of said apical portions inwardly toward said longitudinal axis of said framework such that there is an apical portion so deflected a distance of at least approximately 2 millimeters in response to predetermined loading on said apical portions, which loading is that produced by hemodynamic pressure of approximately 2.3 psi. when a heart valve is mounted on said framework and grafted in the heart of a human, and return of said apical portions to the original positions thereof upon the removal of said predetermined loading.

2. A device as recited in claim 1 in which, for said means for permitting said resilient deflection of said apical portions, said arms are twistable as torsion bars upon the application of said predetermined loading to said apical portions.

3. A device as recited in claim 2 in which said apical portions are relatively rigid so as to be substantially undistorted upon the application of said predetermined loading to said apical portions.

4. A device as recited in claim 2 in which said framework includes additional arms collectively of annular shape, said additional arms being spaced axially from said first-mentioned arms and relatively closer to said apical portions.

5. A device as recited in claim 4 in which said additional arms incline axially away from said apical portions intermediate said apical portions.

6. A device as recited in claim 5 in which said additional arms are deflectable to take a permanent set while retaining the resilience thereof for varying the distances thereof from the axis of said framework.

7. A device as recited in claim 6 including in addition means interconnecting said first-mentioned arms and said additional arms for stiffening said additional arms.

8. A device as recited in claim 7 in which said means interconnecting said first-mentioned arms and said additional arms includes members connecting to said additional arms at locations angularly spaced from said apical portions.

9. A device as recited in claim 8 in which said members are substantially at the midpoints of said firstmentioned arms and said additional arms.

10. A device as recited in claim 8 in which said members are in pairs, positioned one on either side of each of said apical portions.

11. A device as recited in claim 10 in which said members of each pair are divergent toward said additional arms.

12. A device as recited in claim 11 in which said framework includes a post interconnecting each of said apical portions and said first-mentioned arms, each of said posts being positioned between said members of each of said pairs.

13. A device as recited in claim 2 in which said framework is constructed of a resilient stainless steel material.

14. A device as recited in claim 2 in which said framework is constructed of a resilient plastic material.

15. A device as recited in claim 14 including in addition a metal ring around the exterior of said framework at the end thereof remote from said apical portions for reinforcing said framework.

16. A device as recited in claim 15 in which said framework includes an annular groove receiving said ring, said groove having an inner surface tapering away from said apical portions so that said ring will not restrict said resilient deflection of said apical portions.

17. A heart valve assembly comprising a stent,

said stent including a generally tubular framework having spaced apexes at one end and arms interconnecting said apexes, said apexes being normally spaced a predetermined distance from the longitudinal axis of said framework,

a heart valve on said framework,

said heart valve having commissures substantially at said apexes and cusps having marginal portions adjacent said arms, and

means for attaching said heart valve to said framework,

said framework including means for permitting substantial resilient deflection of said apexes inwardly toward said axis a distance of at least approximately 2 millimeters in response to hemodynamic pressure of approximately 2.3 psi. on said heart valve upon grafting of said heart valve in a heart, and return of said apexes to said predetermined distance from said axis upon removal of said hemodynamic pressure.

18. A device as recited in claim 17 in which, for said means for permitting said resilient deflection of said apical portions, said arms are twistable as torsion bars upon the application of said predetermined loading to said apical portions.

19. A device as recited in claim H8 in which said apical portions are relatively rigid so as to be substantially undistorted upon the application of said predetermined loading to said apical portions.

20. A device as recited in claim 17 including in addition a material selected from the group consisting of cloth or sponge means entirely covering said framework.

21. A device as recited in claim 17 including in addition a first material selected from the group consisting of cloth or sponge means,

said material including an annular element extending over the marginal edge portion of said heart valve at said one end,

said means for attaching said heart valve to said framework including sutures,

said sutures extending through said material and said heart valve with loop portions of said sutures engaging said material for thereby preventing said sutures from pulling through the tissue of said heart valve.

22. A device as recited in claim 21 in which said material includes a sleeve entirely receiving said framework so as to provide an inner layer and an outer layer, and

including an annular bead on the exterior of said outer layer intermediate the ends thereof for providing a means for attachment to a heart.

23. A device as recited in claim 22 in which said bead is integral with said outer layer, and including a ring of a second material selected form the group consisting of sponge or felt received in said head.

24. A device as recited in claim 23 in which said first material includes padding between said layers at the locations of said apexes for protecting said sutures and said layers from being abraded by said framework.

25. A device as recited in claim 24 in which said pad ding includes a layer of felt on both sides of each of said apexes.

26. A device as recited in claim 17 including in addition a material selected from the group consisting of cloth or sponge means,

said material including an uninterrupted sleeve entirely receiving said framework so as to provide an inner layer and an outer layer, and an integral generally flat uninterrupted annular flap at the end of said stent opposite from said one end for providing a means for attachment to a heart. 27. A heart valve assembly comprising a stent,

said stent including a generally tubular framework having spaced apexes at one end and arms interconnecting said apexes, said arms being inclined away from said apexes at locations intermediate said apexes, a heart valve on said framework,

said heart valve having commissures substantially at said apexes and cusps having marginal portions adjacent said arms, an annular member of material selected from the group consisting of cloth or sponge material overlying the marginal edge portion of said heart valve at said one end, and sutures extending through said annular member and said marginal edge portions for attaching said heart valve to said framework, said sutures having loop portions engaging said annular member for thereby protecting said heart valve from damage by said sutures.

Claims (27)

1. A stent for a heart valve comprising a framework of annular configuration, said framework including spaced apical portions extending around the longitudinal axis thereof and arms interconnecting said apical portions, for thereby providing an attachment for the commissures and cusps of a heart valve, said framework including means for permitting substantial resilient deflection of said apical portions inwardly toward said longitudinal axis of said framework such that there is an apical portion so deflected a distance of at least approximately 2 millimeters in response to predetermined loading on said apical portions, which loading is that produced by hemodynamic pressure of approximately 2.3 psi. when a heart valve is mounted on said framework and grafted in the heart of a human, and return of said apical portions to the original positions thereof upon the removal of said predetermined loading.
2. A device as recited in claim 1 in which, for said means for permitting said resilient deflection of said apical portions, said arms are twistable as torsion bars upon the application of said predetermined loading to said apical portions.
3. A device as recited in claim 2 in which said apical portions are relatively rigid so as to be substantially undistorted upon the application of said predetermined loading to said apical portions.
4. A device as recited in claim 2 in which said framework includes additional arms collectively of annular shape, said additional arms being spaced axially from said first-mentioned arms and relatively closer to said apical portions.
5. A device as recited in claim 4 in which said additional arms incline axially away from said apical portions intermediate said apical portions.
6. A device as recited in claim 5 in which said additionAl arms are deflectable to take a permanent set while retaining the resilience thereof for varying the distances thereof from the axis of said framework.
7. A device as recited in claim 6 including in addition means interconnecting said first-mentioned arms and said additional arms for stiffening said additional arms.
8. A device as recited in claim 7 in which said means interconnecting said first-mentioned arms and said additional arms includes members connecting to said additional arms at locations angularly spaced from said apical portions.
9. A device as recited in claim 8 in which said members are substantially at the midpoints of said first-mentioned arms and said additional arms.
10. A device as recited in claim 8 in which said members are in pairs, positioned one on either side of each of said apical portions.
11. A device as recited in claim 10 in which said members of each pair are divergent toward said additional arms.
12. A device as recited in claim 11 in which said framework includes a post interconnecting each of said apical portions and said first-mentioned arms, each of said posts being positioned between said members of each of said pairs.
13. A device as recited in claim 2 in which said framework is constructed of a resilient stainless steel material.
14. A device as recited in claim 2 in which said framework is constructed of a resilient plastic material.
15. A device as recited in claim 14 including in addition a metal ring around the exterior of said framework at the end thereof remote from said apical portions for reinforcing said framework.
16. A device as recited in claim 15 in which said framework includes an annular groove receiving said ring, said groove having an inner surface tapering away from said apical portions so that said ring will not restrict said resilient deflection of said apical portions.
17. A heart valve assembly comprising a stent, said stent including a generally tubular framework having spaced apexes at one end and arms inter-connecting said apexes, said apexes being normally spaced a predeter-mined distance from the longitudinal axis of said framework, a heart valve on said framework, said heart valve having commissures substantially at said apexes and cusps having marginal portions adjacent said arms, and means for attaching said heart valve to said framework, said framework including means for permitting substantial resilient deflection of said apexes inwardly toward said axis a distance of at least approximately 2 millimeters in response to hemodynamic pressure of approximately 2.3 psi. on said heart valve upon grafting of said heart valve in a heart, and return of said apexes to said predetermined distance from said axis upon removal of said hemodynamic pressure.
18. A device as recited in claim 17 in which, for said means for permitting said resilient deflection of said apical portions, said arms are twistable as torsion bars upon the application of said predetermined loading to said apical portions.
19. A device as recited in claim 18 in which said apical portions are relatively rigid so as to be substantially undistorted upon the application of said predetermined loading to said apical portions.
20. A device as recited in claim 17 including in addition a material selected from the group consisting of cloth or sponge means entirely covering said framework.
21. A device as recited in claim 17 including in addition a first material selected from the group consisting of cloth or sponge means, said material including an annular element extending over the marginal edge portion of said heart valve at said one end, said means for attaching said heart valve to said framework including sutures, said sutures extending through said material and said heart valve with loop portions of said sutures engaging said material for thereby preventing said sutures from pulling through the tissue of said heart valve.
22. A device as recited in claim 21 in which said material includes a sleeve entirely receiving said framework so as to provide an inner layer and an outer layer, and including an annular bead on the exterior of said outer layer intermediate the ends thereof for providing a means for attachment to a heart.
23. A device as recited in claim 22 in which said bead is integral with said outer layer, and including a ring of a second material selected form the group consisting of sponge or felt received in said bead.
24. A device as recited in claim 23 in which said first material includes padding between said layers at the locations of said apexes for protecting said sutures and said layers from being abraded by said framework.
25. A device as recited in claim 24 in which said padding includes a layer of felt on both sides of each of said apexes.
26. A device as recited in claim 17 including in addition a material selected from the group consisting of cloth or sponge means, said material including an uninterrupted sleeve entirely receiving said framework so as to provide an inner layer and an outer layer, and an integral generally flat uninterrupted annular flap at the end of said stent opposite from said one end for providing a means for attachment to a heart.
27. A heart valve assembly comprising a stent, said stent including a generally tubular framework having spaced apexes at one end and arms interconnecting said apexes, said arms being inclined away from said apexes at locations intermediate said apexes, a heart valve on said framework, said heart valve having commissures substantially at said apexes and cusps having marginal portions adjacent said arms, an annular member of material selected from the group consisting of cloth or sponge material overlying the marginal edge portion of said heart valve at said one end, and sutures extending through said annular member and said marginal edge portions for attaching said heart valve to said framework, said sutures having loop portions engaging said annular member for thereby protecting said heart valve from damage by said sutures.
US3755823A 1971-04-23 1971-04-23 Flexible stent for heart valve Expired - Lifetime US3755823A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
US13683271 true 1971-04-23 1971-04-23

Publications (1)

Publication Number Publication Date
US3755823A true US3755823A (en) 1973-09-04

Family

ID=22474569

Family Applications (1)

Application Number Title Priority Date Filing Date
US3755823A Expired - Lifetime US3755823A (en) 1971-04-23 1971-04-23 Flexible stent for heart valve

Country Status (1)

Country Link
US (1) US3755823A (en)

Cited By (278)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3983581A (en) * 1975-01-20 1976-10-05 William W. Angell Heart valve stent
US4035849A (en) * 1975-11-17 1977-07-19 William W. Angell Heart valve stent and process for preparing a stented heart valve prosthesis
US4084268A (en) * 1976-04-22 1978-04-18 Shiley Laboratories, Incorporated Prosthetic tissue heart valve
US4106129A (en) * 1976-01-09 1978-08-15 American Hospital Supply Corporation Supported bioprosthetic heart valve with compliant orifice ring
DE2807467A1 (en) * 1977-02-23 1978-08-24 Robert Bernard Davis Heart valve prosthesis
US4218782A (en) * 1977-05-25 1980-08-26 Biocoating Anpartsselskab Heart valve prosthesis and method for the production thereof
US4222126A (en) * 1978-12-14 1980-09-16 The United States Of America As Represented By The Secretary Of The Department Of Health, Education & Welfare Unitized three leaflet heart valve
FR2451189A1 (en) * 1979-03-16 1980-10-10 Liotta Domingo Support for the heart valves of biological tissues
US4265694A (en) * 1978-12-14 1981-05-05 The United States Of America As Represented By The Department Of Health, Education And Welfare Method of making unitized three leaflet heart valve
US4275469A (en) * 1979-12-13 1981-06-30 Shelhigh Inc. Prosthetic heart valve
US4297749A (en) * 1977-04-25 1981-11-03 Albany International Corp. Heart valve prosthesis
US4340977A (en) * 1980-09-19 1982-07-27 Brownlee Richard T Catenary mitral valve replacement
US4343048A (en) * 1979-08-06 1982-08-10 Ross Donald N Stent for a cardiac valve
US4345340A (en) * 1981-05-07 1982-08-24 Vascor, Inc. Stent for mitral/tricuspid heart valve
US4350492A (en) * 1981-08-24 1982-09-21 Vascor, Inc. Method for preparing tissue heart valve
US4364127A (en) * 1981-10-02 1982-12-21 Research Corporation Trileaflet type prosthetic heart valve
FR2510396A1 (en) * 1981-07-28 1983-02-04 Extracorporeal Med Spec heart valve protection device
WO1983000617A1 (en) * 1981-08-17 1983-03-03 American Hospital Supply Corp Leaflet attachment and method of attachment for prosthetic heart valves
WO1983002225A1 (en) * 1981-12-21 1983-07-07 American Hospital Supply Corp Supra-annular valve
US4470157A (en) * 1981-04-27 1984-09-11 Love Jack W Tricuspid prosthetic tissue heart valve
US4473423A (en) * 1982-05-03 1984-09-25 University Of Utah Artificial heart valve made by vacuum forming technique
US4477930A (en) * 1982-09-28 1984-10-23 Mitral Medical International, Inc. Natural tissue heat valve and method of making same
US4490859A (en) * 1982-01-20 1985-01-01 University Of Sheffield Artificial heart valves
US4510628A (en) * 1982-05-03 1985-04-16 University Of Utah Artificial heart valve made by vacuum forming technique
EP0143246A2 (en) * 1983-09-23 1985-06-05 Peter Kennedy Pty. Ltd. Heart valve prosthesis
EP0150608A1 (en) * 1983-12-28 1985-08-07 Shiley Inc. Stent covering for tissue valves
EP0155245A2 (en) * 1984-03-16 1985-09-18 SORIN BIOMEDICA S.p.A. Cardiac valve prosthesis with valve flaps of biological tissues
US4556996A (en) * 1983-08-04 1985-12-10 Robert S. Wallace Heart valve
EP0071610B1 (en) * 1981-02-04 1986-03-12 Institutul De Cercetari Veterinare Si Biopreparate "Pasteur" Cardiac valvular bioprosthesis and the method of manufacture thereof
US4692164A (en) * 1986-03-06 1987-09-08 Moskovskoe Vysshee Tekhnicheskoe Uchilische, Imeni N.E. Baumana Bioprosthetic heart valve, methods and device for preparation thereof
US4759758A (en) * 1984-12-07 1988-07-26 Shlomo Gabbay Prosthetic heart valve
WO1989000840A1 (en) * 1987-07-31 1989-02-09 Pacific Biomedical Holdings, Ltd. Bioprosthetic valve stent
US4816029A (en) * 1981-05-07 1989-03-28 Medtronic, Inc. Stent for aortic heart valve
US4865600A (en) * 1981-08-25 1989-09-12 Baxter International Inc. Mitral valve holder
US4932965A (en) * 1988-12-19 1990-06-12 Phillips Steven J Artificial valve, and needle and suture holder and method of using same
WO1990011738A1 (en) * 1989-04-05 1990-10-18 Alexander Bernhard Heart valve prosthesis for replacement of the aortic valve
WO1992009247A1 (en) * 1990-11-29 1992-06-11 Anschütz & Co. Gmbh Support ring for a biological aortic-valve prosthesis
WO1992019185A1 (en) * 1991-05-08 1992-11-12 Nika Health Products Limited Process and apparatus for the production of a heart valve prosthesis
US5163955A (en) * 1991-01-24 1992-11-17 Autogenics Rapid assembly, concentric mating stent, tissue heart valve with enhanced clamping and tissue alignment
WO1994001060A1 (en) * 1992-07-10 1994-01-20 Adiam Medizintechnik Gmbh & Co. Kg Support housing for valve and closure members
US5425741A (en) * 1993-12-17 1995-06-20 Autogenics Tissue cutting die
US5449385A (en) * 1991-05-08 1995-09-12 Nika Health Products Limited Support for a heart valve prosthesis
US5489298A (en) * 1991-01-24 1996-02-06 Autogenics Rapid assembly concentric mating stent, tissue heart valve with enhanced clamping and tissue exposure
US5562729A (en) * 1994-11-01 1996-10-08 Biocontrol Technology, Inc. Heart valve
US5612885A (en) * 1993-12-17 1997-03-18 Autogenics Method for constructing a heart valve stent
US5755687A (en) * 1997-04-01 1998-05-26 Heartport, Inc. Methods and devices for occluding a patient's ascending aorta
US5765568A (en) * 1994-05-27 1998-06-16 Heartport, Inc. Catheter system and method for venting the left ventricle
US5792094A (en) * 1991-07-16 1998-08-11 Heartport, Inc. Method of delivering cardioplegic fluid to a patient's heart
US5840081A (en) * 1990-05-18 1998-11-24 Andersen; Henning Rud System and method for implanting cardiac valves
US5928281A (en) * 1997-03-27 1999-07-27 Baxter International Inc. Tissue heart valves
WO2000062715A1 (en) * 1999-04-16 2000-10-26 Edwards Lifesciences Corporation Aortic annuloplasty ring
WO2001030275A1 (en) * 1999-10-29 2001-05-03 Fundacja Rozwoju Kardiochirurgii Heart valve stent, in particular mitral heart valve stent
US6250308B1 (en) 1998-06-16 2001-06-26 Cardiac Concepts, Inc. Mitral valve annuloplasty ring and method of implanting
WO2001062189A1 (en) * 2000-02-28 2001-08-30 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Device for fastening and anchoring cardiac valve prostheses
US6334873B1 (en) 1998-09-28 2002-01-01 Autogenics Heart valve having tissue retention with anchors and an outer sheath
US6338735B1 (en) 1991-07-16 2002-01-15 John H. Stevens Methods for removing embolic material in blood flowing through a patient's ascending aorta
US6454799B1 (en) * 2000-04-06 2002-09-24 Edwards Lifesciences Corporation Minimally-invasive heart valves and methods of use
US6461382B1 (en) 2000-09-22 2002-10-08 Edwards Lifesciences Corporation Flexible heart valve having moveable commissures
US20020151970A1 (en) * 1999-02-10 2002-10-17 Garrison Michi E. Methods and devices for implanting cardiac valves
US6482171B1 (en) 1991-07-16 2002-11-19 Heartport, Inc. Multi-lumen catheter
US20030044596A1 (en) * 1999-10-19 2003-03-06 Lazarov Miladin P. Biocompatible article
US20030109924A1 (en) * 1996-12-31 2003-06-12 Alain Cribier Implanting a valve prosthesis in body channels
US20030125805A1 (en) * 2002-01-02 2003-07-03 Medtronic, Inc. Heart valve system
US20030167089A1 (en) * 2001-12-27 2003-09-04 Ernest Lane Bioprosthetic heart valve
US6635085B1 (en) * 2000-08-17 2003-10-21 Carbomedics Inc. Heart valve stent with alignment posts
US20040024451A1 (en) * 2002-01-02 2004-02-05 Medtronic, Inc. Prosthetic heart valve system
US20040039436A1 (en) * 2001-10-11 2004-02-26 Benjamin Spenser Implantable prosthetic valve
US20040044402A1 (en) * 2002-09-03 2004-03-04 M.I. Tech Co., Ltd. Stent and method for manufacturing the same
US20040049262A1 (en) * 2000-01-31 2004-03-11 Obermiller Joseph F. Stent valves and uses of same
US20040088045A1 (en) * 1993-11-01 2004-05-06 3F Therapeutics, Inc. Replacement heart valve
US20040122514A1 (en) * 2002-12-20 2004-06-24 Fogarty Thomas J. Biologically implantable prosthesis and methods of using the same
US20040186563A1 (en) * 2003-03-18 2004-09-23 Lobbi Mario M. Minimally-invasive heart valve with cusp positioners
US20050033398A1 (en) * 2001-07-31 2005-02-10 Jacques Seguin Assembly for setting a valve prosthesis in a corporeal duct
US20050043790A1 (en) * 2001-07-04 2005-02-24 Jacques Seguin Kit enabling a prosthetic valve to be placed in a body enabling a prosthetic valve to be put into place in a duct in the body
WO2005065594A1 (en) * 2003-12-19 2005-07-21 Boston Scientific Limited Venous valve apparatus, system, and method
US20050197695A1 (en) * 2004-03-03 2005-09-08 Sorin Biomedica Cardio S.R.L. Minimally-invasive cardiac-valve prosthesis
US6951571B1 (en) 2004-09-30 2005-10-04 Rohit Srivastava Valve implanting device
US20060004439A1 (en) * 2004-06-30 2006-01-05 Benjamin Spenser Device and method for assisting in the implantation of a prosthetic valve
US20060004442A1 (en) * 2004-06-30 2006-01-05 Benjamin Spenser Paravalvular leak detection, sealing, and prevention
US20060015179A1 (en) * 2004-07-19 2006-01-19 Neil Bulman-Fleming Aortic annuloplasty ring
US7018407B1 (en) 1981-10-29 2006-03-28 Medtronic Valve holder for tricuspid heart valve
US7018406B2 (en) 1999-11-17 2006-03-28 Corevalve Sa Prosthetic valve for transluminal delivery
US20060259136A1 (en) * 2005-05-13 2006-11-16 Corevalve Sa Heart valve prosthesis and methods of manufacture and use
US7147640B2 (en) 2003-03-12 2006-12-12 Acumed Llc External fixator
US20070162107A1 (en) 2003-12-23 2007-07-12 Sadra Medical, Inc. Methods and apparatus for endovascularly replacing a patient's heart valve
US20070219630A1 (en) * 2004-11-24 2007-09-20 Xi Chu Devices and Methods for Beating Heart Cardiac Surgeries
US20070239254A1 (en) * 2006-04-07 2007-10-11 Chris Chia System for percutaneous delivery and removal of a prosthetic valve
US20080147179A1 (en) * 2006-12-19 2008-06-19 St. Jude Medical, Inc. Prosthetic heart valve including stent structure and tissue leaflets, and related methods
US20080154355A1 (en) * 2006-12-22 2008-06-26 Netanel Benichou Implantable prosthetic valve assembly and method of making the same
US20080200978A1 (en) * 2005-05-26 2008-08-21 Texas Heart Institute Surgical System and Method For Attaching a Prosthetic Vessel to a Hollow Structure
US20080275549A1 (en) * 2003-10-02 2008-11-06 Edwards Lifesciences Pvt, Inc. Implantable prosthetic valve with non-laminar flow
US20090076599A1 (en) * 2007-09-17 2009-03-19 Medtronics, Inc. Heart valve holder assembly for use in valve implantation procedures
US20090082619A1 (en) * 2005-06-09 2009-03-26 De Marchena Eduardo Method of treating cardiomyopathy
US20090099410A1 (en) * 2005-06-09 2009-04-16 De Marchena Eduardo Papillary Muscle Attachment for Left Ventricular Reduction
US7544206B2 (en) 2001-06-29 2009-06-09 Medtronic, Inc. Method and apparatus for resecting and replacing an aortic valve
US20090157175A1 (en) * 2007-12-14 2009-06-18 Edwards Lifesciences Corporation Leaflet attachment frame for a prosthetic valve
US20090228093A1 (en) * 2008-02-29 2009-09-10 Edwards Lifesciences Corporation Expandable member for deploying a prosthetic device
US7611535B2 (en) 2001-09-07 2009-11-03 Medtronic, Inc. Fixation band for affixing a prosthetic heart valve to tissue
US20090276040A1 (en) * 2008-05-01 2009-11-05 Edwards Lifesciences Corporation Device and method for replacing mitral valve
US20090281619A1 (en) * 2008-05-09 2009-11-12 Edwards Lifesciences Corporation Low Profile Delivery System for Transcatheter Heart Valve
US20090287296A1 (en) * 2008-05-16 2009-11-19 Sorin Biomedica Cardio S.R.L. Atraumatic prosthetic heart valve prosthesis
US20090319037A1 (en) * 2008-06-20 2009-12-24 Edwards Lifesciences Corporation Retaining mechanisms for prosthetic valves
US7637937B2 (en) 2004-04-08 2009-12-29 Cook Incorporated Implantable medical device with optimized shape
US20100049313A1 (en) * 2008-08-22 2010-02-25 Edwards Lifesciences Corporation Prosthetic heart valve and delivery apparatus
US20100161036A1 (en) * 2008-12-19 2010-06-24 Edwards Lifesciences Corporation Quick-connect prosthetic heart valve and methods
US7749266B2 (en) 2006-02-27 2010-07-06 Aortx, Inc. Methods and devices for delivery of prosthetic heart valves and other prosthetics
US20100174359A1 (en) * 2008-10-29 2010-07-08 Symetis Sa Methods and Systems for Stent-Valve Manufacture and Assembly
US7758606B2 (en) 2000-06-30 2010-07-20 Medtronic, Inc. Intravascular filter with debris entrapment mechanism
US20100185278A1 (en) * 2009-01-21 2010-07-22 Tendyne Medical Apical Papillary Msucle Attachment for Left Ventricular Reduction
US20100217382A1 (en) * 2009-02-25 2010-08-26 Edwards Lifesciences Mitral valve replacement with atrial anchoring
US7785341B2 (en) 2004-02-27 2010-08-31 Aortx, Inc. Prosthetic heart valves, scaffolding structures, and systems and methods for implantation of same
US7819915B2 (en) 2000-07-27 2010-10-26 Edwards Lifesciences Corporation Heart valve holders and handling clips therefor
US20100274351A1 (en) * 2009-04-27 2010-10-28 Sorin Biomedica Cardio S.R.I. Prosthetic vascular conduit
US7846199B2 (en) 2007-11-19 2010-12-07 Cook Incorporated Remodelable prosthetic valve
US20100331972A1 (en) * 2009-06-26 2010-12-30 Edwards Lifesciences Corporation Unitary Quick Connect Prosthetic Heart Valve and Deployment System and Methods
US7951197B2 (en) 2005-04-08 2011-05-31 Medtronic, Inc. Two-piece prosthetic valves with snap-in connection and methods for use
US7959674B2 (en) 2002-07-16 2011-06-14 Medtronic, Inc. Suture locking assembly and method of use
US7967857B2 (en) 2006-01-27 2011-06-28 Medtronic, Inc. Gasket with spring collar for prosthetic heart valves and methods for making and using them
US7972378B2 (en) 2008-01-24 2011-07-05 Medtronic, Inc. Stents for prosthetic heart valves
US7993394B2 (en) 2008-06-06 2011-08-09 Ilia Hariton Low profile transcatheter heart valve
US8016877B2 (en) 1999-11-17 2011-09-13 Medtronic Corevalve Llc Prosthetic valve for transluminal delivery
US8021161B2 (en) 2006-05-01 2011-09-20 Edwards Lifesciences Corporation Simulated heart valve root for training and testing
US8021421B2 (en) 2003-08-22 2011-09-20 Medtronic, Inc. Prosthesis heart valve fixturing device
US20110257721A1 (en) * 2010-04-15 2011-10-20 Medtronic, Inc. Prosthetic Heart Valves and Delivery Methods
US8052750B2 (en) 2006-09-19 2011-11-08 Medtronic Ventor Technologies Ltd Valve prosthesis fixation techniques using sandwiching
US8052749B2 (en) 2003-12-23 2011-11-08 Sadra Medical, Inc. Methods and apparatus for endovascular heart valve replacement comprising tissue grasping elements
US8057396B2 (en) 2006-05-24 2011-11-15 Phoenix Biomedical, Inc. Device for assessing a cardiac valve
US8075615B2 (en) 2006-03-28 2011-12-13 Medtronic, Inc. Prosthetic cardiac valve formed from pericardium material and methods of making same
US8137398B2 (en) 2008-10-13 2012-03-20 Medtronic Ventor Technologies Ltd Prosthetic valve having tapered tip when compressed for delivery
US8142492B2 (en) 2006-06-21 2012-03-27 Aortx, Inc. Prosthetic valve implantation systems
US8147541B2 (en) 2006-02-27 2012-04-03 Aortx, Inc. Methods and devices for delivery of prosthetic heart valves and other prosthetics
US8157853B2 (en) 2008-01-24 2012-04-17 Medtronic, Inc. Delivery systems and methods of implantation for prosthetic heart valves
US8182528B2 (en) 2003-12-23 2012-05-22 Sadra Medical, Inc. Locking heart valve anchor
US8206438B2 (en) 2001-03-23 2012-06-26 Edwards Lifesciences Corporation Prosthetic heart valve having flared outflow section
US8211169B2 (en) 2005-05-27 2012-07-03 Medtronic, Inc. Gasket with collar for prosthetic heart valves and methods for using them
US8216299B2 (en) 2004-04-01 2012-07-10 Cook Medical Technologies Llc Method to retract a body vessel wall with remodelable material
US8231670B2 (en) 2003-12-23 2012-07-31 Sadra Medical, Inc. Repositionable heart valve and method
US8241274B2 (en) 2000-01-19 2012-08-14 Medtronic, Inc. Method for guiding a medical device
US8252052B2 (en) 2003-12-23 2012-08-28 Sadra Medical, Inc. Methods and apparatus for endovascularly replacing a patient's heart valve
US8312825B2 (en) 2008-04-23 2012-11-20 Medtronic, Inc. Methods and apparatuses for assembly of a pericardial prosthetic heart valve
US8313525B2 (en) 2008-03-18 2012-11-20 Medtronic Ventor Technologies, Ltd. Valve suturing and implantation procedures
US8328868B2 (en) 2004-11-05 2012-12-11 Sadra Medical, Inc. Medical devices and delivery systems for delivering medical devices
US8343213B2 (en) 2003-12-23 2013-01-01 Sadra Medical, Inc. Leaflet engagement elements and methods for use thereof
US20130018458A1 (en) * 2011-07-15 2013-01-17 Edwards Lifesciences Corporation Perivalvular sealing for transcatheter heart valve
US8376865B2 (en) 2006-06-20 2013-02-19 Cardiacmd, Inc. Torque shaft and torque shaft drive
US8430927B2 (en) 2008-04-08 2013-04-30 Medtronic, Inc. Multiple orifice implantable heart valve and methods of implantation
US8449625B2 (en) 2009-10-27 2013-05-28 Edwards Lifesciences Corporation Methods of measuring heart valve annuluses for valve replacement
US8449599B2 (en) 2009-12-04 2013-05-28 Edwards Lifesciences Corporation Prosthetic valve for replacing mitral valve
US8500799B2 (en) 2006-06-20 2013-08-06 Cardiacmd, Inc. Prosthetic heart valves, support structures and systems and methods for implanting same
US8506625B2 (en) 2005-07-13 2013-08-13 Edwards Lifesciences Corporation Contoured sewing ring for a prosthetic mitral heart valve
US8540768B2 (en) 2005-02-10 2013-09-24 Sorin Group Italia S.R.L. Cardiac valve prosthesis
US8562672B2 (en) 2004-11-19 2013-10-22 Medtronic, Inc. Apparatus for treatment of cardiac valves and method of its manufacture
US8568475B2 (en) 2010-10-05 2013-10-29 Edwards Lifesciences Corporation Spiraled commissure attachment for prosthetic valve
US8574257B2 (en) 2005-02-10 2013-11-05 Edwards Lifesciences Corporation System, device, and method for providing access in a cardiovascular environment
US8579962B2 (en) 2003-12-23 2013-11-12 Sadra Medical, Inc. Methods and apparatus for performing valvuloplasty
US8579966B2 (en) 1999-11-17 2013-11-12 Medtronic Corevalve Llc Prosthetic valve for transluminal delivery
US8591570B2 (en) 2004-09-07 2013-11-26 Medtronic, Inc. Prosthetic heart valve for replacing previously implanted heart valve
US8603161B2 (en) 2003-10-08 2013-12-10 Medtronic, Inc. Attachment device and methods of using the same
US8603160B2 (en) 2003-12-23 2013-12-10 Sadra Medical, Inc. Method of using a retrievable heart valve anchor with a sheath
US8613765B2 (en) 2008-02-28 2013-12-24 Medtronic, Inc. Prosthetic heart valve systems
US20140005773A1 (en) * 2011-02-18 2014-01-02 David J. Wheatley Heart Valve
US8623077B2 (en) 2001-06-29 2014-01-07 Medtronic, Inc. Apparatus for replacing a cardiac valve
US8623076B2 (en) 2003-12-23 2014-01-07 Sadra Medical, Inc. Low profile heart valve and delivery system
US8628566B2 (en) 2008-01-24 2014-01-14 Medtronic, Inc. Stents for prosthetic heart valves
US8641757B2 (en) 2010-09-10 2014-02-04 Edwards Lifesciences Corporation Systems for rapidly deploying surgical heart valves
US20140039614A1 (en) * 2007-08-21 2014-02-06 Symetis Sa Stent-Valves For Valve Replacement and Associated Methods and Systems for Surgery
US8652204B2 (en) 2010-04-01 2014-02-18 Medtronic, Inc. Transcatheter valve with torsion spring fixation and related systems and methods
US8668733B2 (en) 2004-06-16 2014-03-11 Sadra Medical, Inc. Everting heart valve
US8685084B2 (en) 2011-12-29 2014-04-01 Sorin Group Italia S.R.L. Prosthetic vascular conduit and assembly method
US8696743B2 (en) 2008-04-23 2014-04-15 Medtronic, Inc. Tissue attachment devices and methods for prosthetic heart valves
US8721713B2 (en) 2002-04-23 2014-05-13 Medtronic, Inc. System for implanting a replacement valve
US8721714B2 (en) 2008-09-17 2014-05-13 Medtronic Corevalve Llc Delivery system for deployment of medical devices
US8747458B2 (en) 2007-08-20 2014-06-10 Medtronic Ventor Technologies Ltd. Stent loading tool and method for use thereof
US8747459B2 (en) 2006-12-06 2014-06-10 Medtronic Corevalve Llc System and method for transapical delivery of an annulus anchored self-expanding valve
US8771302B2 (en) 2001-06-29 2014-07-08 Medtronic, Inc. Method and apparatus for resecting and replacing an aortic valve
US8795354B2 (en) 2010-03-05 2014-08-05 Edwards Lifesciences Corporation Low-profile heart valve and delivery system
WO2014120507A1 (en) * 2013-01-29 2014-08-07 St. Jude Medical, Cardiology Division, Inc. Surgical heart valve flexible stent frame stiffener
US8808369B2 (en) 2009-10-05 2014-08-19 Mayo Foundation For Medical Education And Research Minimally invasive aortic valve replacement
US8821569B2 (en) 2006-04-29 2014-09-02 Medtronic, Inc. Multiple component prosthetic heart valve assemblies and methods for delivering them
USRE45130E1 (en) 2000-02-28 2014-09-09 Jenavalve Technology Gmbh Device for fastening and anchoring cardiac valve prostheses
US8834564B2 (en) 2006-09-19 2014-09-16 Medtronic, Inc. Sinus-engaging valve fixation member
US8834563B2 (en) 2008-12-23 2014-09-16 Sorin Group Italia S.R.L. Expandable prosthetic valve having anchoring appendages
US8840663B2 (en) 2003-12-23 2014-09-23 Sadra Medical, Inc. Repositionable heart valve method
US8845720B2 (en) 2010-09-27 2014-09-30 Edwards Lifesciences Corporation Prosthetic heart valve frame with flexible commissures
US8858620B2 (en) 2003-12-23 2014-10-14 Sadra Medical Inc. Methods and apparatus for endovascularly replacing a heart valve
US8894703B2 (en) 2003-12-23 2014-11-25 Sadra Medical, Inc. Systems and methods for delivering a medical implant
US8986374B2 (en) 2010-05-10 2015-03-24 Edwards Lifesciences Corporation Prosthetic heart valve
US8986361B2 (en) 2008-10-17 2015-03-24 Medtronic Corevalve, Inc. Delivery system for deployment of medical devices
US8998981B2 (en) 2008-09-15 2015-04-07 Medtronic, Inc. Prosthetic heart valve having identifiers for aiding in radiographic positioning
US8998976B2 (en) 2011-07-12 2015-04-07 Boston Scientific Scimed, Inc. Coupling system for medical devices
US9005273B2 (en) 2003-12-23 2015-04-14 Sadra Medical, Inc. Assessing the location and performance of replacement heart valves
US9011521B2 (en) 2003-12-23 2015-04-21 Sadra Medical, Inc. Methods and apparatus for endovascularly replacing a patient's heart valve
US9028545B2 (en) 2005-06-13 2015-05-12 Edwards Lifesciences Corporation Method of delivering a prosthetic heart valve
US9078747B2 (en) 2011-12-21 2015-07-14 Edwards Lifesciences Corporation Anchoring device for replacing or repairing a heart valve
US9078749B2 (en) 2007-09-13 2015-07-14 Georg Lutter Truncated cone heart valve stent
US9078781B2 (en) 2006-01-11 2015-07-14 Medtronic, Inc. Sterile cover for compressible stents used in percutaneous device delivery systems
US9089422B2 (en) 2008-01-24 2015-07-28 Medtronic, Inc. Markers for prosthetic heart valves
US9119716B2 (en) 2011-07-27 2015-09-01 Edwards Lifesciences Corporation Delivery systems for prosthetic heart valve
US9125741B2 (en) 2010-09-10 2015-09-08 Edwards Lifesciences Corporation Systems and methods for ensuring safe and rapid deployment of prosthetic heart valves
US9149358B2 (en) 2008-01-24 2015-10-06 Medtronic, Inc. Delivery systems for prosthetic heart valves
US9155619B2 (en) 2011-02-25 2015-10-13 Edwards Lifesciences Corporation Prosthetic heart valve delivery apparatus
US9155617B2 (en) 2004-01-23 2015-10-13 Edwards Lifesciences Corporation Prosthetic mitral valve
US9161836B2 (en) 2011-02-14 2015-10-20 Sorin Group Italia S.R.L. Sutureless anchoring device for cardiac valve prostheses
US9168129B2 (en) 2013-02-12 2015-10-27 Edwards Lifesciences Corporation Artificial heart valve with scalloped frame design
US9168136B2 (en) 2001-09-13 2015-10-27 Edwards Lifesciences Corporation Methods for deploying self-expanding heart valves
US9168131B2 (en) 2011-12-09 2015-10-27 Edwards Lifesciences Corporation Prosthetic heart valve having improved commissure supports
US9216082B2 (en) 2005-12-22 2015-12-22 Symetis Sa Stent-valves for valve replacement and associated methods and systems for surgery
US9226826B2 (en) 2010-02-24 2016-01-05 Medtronic, Inc. Transcatheter valve structure and methods for valve delivery
US9237886B2 (en) 2007-04-20 2016-01-19 Medtronic, Inc. Implant for treatment of a heart valve, in particular a mitral valve, material including such an implant, and material for insertion thereof
US9241792B2 (en) 2008-02-29 2016-01-26 Edwards Lifesciences Corporation Two-step heart valve implantation
US9248016B2 (en) 2009-03-31 2016-02-02 Edwards Lifesciences Corporation Prosthetic heart valve system
US9248017B2 (en) 2010-05-21 2016-02-02 Sorin Group Italia S.R.L. Support device for valve prostheses and corresponding kit
US9289289B2 (en) 2011-02-14 2016-03-22 Sorin Group Italia S.R.L. Sutureless anchoring device for cardiac valve prostheses
US9289282B2 (en) 2011-05-31 2016-03-22 Edwards Lifesciences Corporation System and method for treating valve insufficiency or vessel dilatation
US9301840B2 (en) 2008-10-10 2016-04-05 Edwards Lifesciences Corporation Expandable introducer sheath
US9314334B2 (en) 2008-11-25 2016-04-19 Edwards Lifesciences Corporation Conformal expansion of prosthetic devices to anatomical shapes
US9326853B2 (en) 2010-07-23 2016-05-03 Edwards Lifesciences Corporation Retaining mechanisms for prosthetic valves
US9370421B2 (en) 2011-12-03 2016-06-21 Boston Scientific Scimed, Inc. Medical device handle
US9370418B2 (en) 2010-09-10 2016-06-21 Edwards Lifesciences Corporation Rapidly deployable surgical heart valves
US9375312B2 (en) 2010-07-09 2016-06-28 Highlife Sas Transcatheter atrio-ventricular valve prosthesis
US9393115B2 (en) 2008-01-24 2016-07-19 Medtronic, Inc. Delivery systems and methods of implantation for prosthetic heart valves
US9393110B2 (en) 2010-10-05 2016-07-19 Edwards Lifesciences Corporation Prosthetic heart valve
US9415225B2 (en) 2005-04-25 2016-08-16 Cardiac Pacemakers, Inc. Method and apparatus for pacing during revascularization
US9414918B2 (en) 2012-09-06 2016-08-16 Edwards Lifesciences Corporation Heart valve sealing devices
US9439762B2 (en) 2000-06-01 2016-09-13 Edwards Lifesciences Corporation Methods of implant of a heart valve with a convertible sewing ring
US9439763B2 (en) 2013-02-04 2016-09-13 Edwards Lifesciences Corporation Prosthetic valve for replacing mitral valve
US9468527B2 (en) 2013-06-12 2016-10-18 Edwards Lifesciences Corporation Cardiac implant with integrated suture fasteners
US9474598B2 (en) 2011-10-05 2016-10-25 Boston Scientific Scimed, Inc. Profile reduction seal
US9480559B2 (en) 2011-08-11 2016-11-01 Tendyne Holdings, Inc. Prosthetic valves and related inventions
US9486306B2 (en) 2013-04-02 2016-11-08 Tendyne Holdings, Inc. Inflatable annular sealing device for prosthetic mitral valve
US9504566B2 (en) 2014-06-20 2016-11-29 Edwards Lifesciences Corporation Surgical heart valves identifiable post-implant
US9504568B2 (en) 2007-02-16 2016-11-29 Medtronic, Inc. Replacement prosthetic heart valves and methods of implantation
US9510947B2 (en) 2011-10-21 2016-12-06 Jenavalve Technology, Inc. Catheter system for introducing an expandable heart valve stent into the body of a patient
US9526609B2 (en) 2003-12-23 2016-12-27 Boston Scientific Scimed, Inc. Methods and apparatus for endovascularly replacing a patient's heart valve
US9526611B2 (en) 2013-10-29 2016-12-27 Tendyne Holdings, Inc. Apparatus and methods for delivery of transcatheter prosthetic valves
US9532870B2 (en) 2014-06-06 2017-01-03 Edwards Lifesciences Corporation Prosthetic valve for replacing a mitral valve
US9549816B2 (en) 2014-04-03 2017-01-24 Edwards Lifesciences Corporation Method for manufacturing high durability heart valve
US9554903B2 (en) 2005-05-24 2017-01-31 Edwards Lifesciences Corporation Rapid deployment prosthetic heart valve
US9554901B2 (en) 2010-05-12 2017-01-31 Edwards Lifesciences Corporation Low gradient prosthetic heart valve
US9585752B2 (en) 2014-04-30 2017-03-07 Edwards Lifesciences Corporation Holder and deployment system for surgical heart valves
US9597181B2 (en) 2013-06-25 2017-03-21 Tendyne Holdings, Inc. Thrombus management and structural compliance features for prosthetic heart valves
US9610159B2 (en) 2013-05-30 2017-04-04 Tendyne Holdings, Inc. Structural members for prosthetic mitral valves
US9622863B2 (en) 2013-11-22 2017-04-18 Edwards Lifesciences Corporation Aortic insufficiency repair device and method
US9629718B2 (en) 2013-05-03 2017-04-25 Medtronic, Inc. Valve delivery tool
US9636221B2 (en) 2007-09-26 2017-05-02 St. Jude Medical, Inc. Collapsible prosthetic heart valves
US9675449B2 (en) 2008-07-15 2017-06-13 St. Jude Medical, Llc Collapsible and re-expandable prosthetic heart valve cuff designs and complementary technological applications
US9675454B2 (en) 2012-07-30 2017-06-13 Tendyne Holdings, Inc. Delivery systems and methods for transcatheter prosthetic valves
US9717594B2 (en) 2009-07-14 2017-08-01 Edwards Lifesciences Corporation Methods of valve delivery on a beating heart
US9775704B2 (en) 2004-04-23 2017-10-03 Medtronic3F Therapeutics, Inc. Implantable valve prosthesis
US9788942B2 (en) 2015-02-03 2017-10-17 Boston Scientific Scimed Inc. Prosthetic heart valve having tubular seal
US9820851B2 (en) 2007-09-28 2017-11-21 St. Jude Medical, Llc Collapsible-expandable prosthetic heart valves with structures for clamping native tissue
US9827092B2 (en) 2011-12-16 2017-11-28 Tendyne Holdings, Inc. Tethers for prosthetic mitral valve
US9839513B2 (en) 2007-10-25 2017-12-12 Symetis Sa Stents, valved-stents and methods and systems for delivery thereof
US9848981B2 (en) 2007-10-12 2017-12-26 Mayo Foundation For Medical Education And Research Expandable valve prosthesis with sealing mechanism
US9861477B2 (en) 2015-01-26 2018-01-09 Boston Scientific Scimed Inc. Prosthetic heart valve square leaflet-leaflet stitch
US9867700B2 (en) 2013-05-20 2018-01-16 Edwards Lifesciences Corporation Prosthetic heart valve delivery apparatus
US9867694B2 (en) 2013-08-30 2018-01-16 Jenavalve Technology Inc. Radially collapsible frame for a prosthetic valve and method for manufacturing such a frame
US9878127B2 (en) 2012-05-16 2018-01-30 Jenavalve Technology, Inc. Catheter delivery system for heart valve prosthesis
US9895221B2 (en) 2012-07-28 2018-02-20 Tendyne Holdings, Inc. Multi-component designs for heart valve retrieval device, sealing structures and stent assembly
US9901445B2 (en) 2014-11-21 2018-02-27 Boston Scientific Scimed, Inc. Valve locking mechanism
US9901444B2 (en) 2013-12-17 2018-02-27 Edwards Lifesciences Corporation Inverted valve structure
US9913715B2 (en) 2013-11-06 2018-03-13 St. Jude Medical, Cardiology Division, Inc. Paravalvular leak sealing mechanism
US9918833B2 (en) 2010-09-01 2018-03-20 Medtronic Vascular Galway Prosthetic valve support structure
US9919137B2 (en) 2013-08-28 2018-03-20 Edwards Lifesciences Corporation Integrated balloon catheter inflation system
US9974650B2 (en) 2015-07-14 2018-05-22 Edwards Lifesciences Corporation Prosthetic heart valve
US9986993B2 (en) 2014-02-11 2018-06-05 Tendyne Holdings, Inc. Adjustable tether and epicardial pad system for prosthetic heart valve
US10010417B2 (en) 2015-04-16 2018-07-03 Edwards Lifesciences Corporation Low-profile prosthetic heart valve for replacing a mitral valve
US10016276B2 (en) 2012-11-21 2018-07-10 Edwards Lifesciences Corporation Retaining mechanisms for prosthetic heart valves
US10039637B2 (en) 2015-02-11 2018-08-07 Edwards Lifesciences Corporation Heart valve docking devices and implanting methods
US10052198B2 (en) 2013-08-14 2018-08-21 Mitral Valve Technologies Sarl Coiled anchor for supporting prosthetic heart valve, prosthetic heart valve, and deployment device
US10052199B2 (en) 2014-02-21 2018-08-21 Mitral Valve Technologies Sarl Devices, systems and methods for delivering a prosthetic mitral valve and anchoring device
US10058425B2 (en) 2013-03-15 2018-08-28 Edwards Lifesciences Corporation Methods of assembling a valved aortic conduit
US10058424B2 (en) 2014-08-21 2018-08-28 Edwards Lifesciences Corporation Dual-flange prosthetic valve frame
US10058420B2 (en) 2014-02-18 2018-08-28 Edwards Lifesciences Corporation Flexible commissure frame
US10064718B2 (en) 2015-04-16 2018-09-04 Edwards Lifesciences Corporation Low-profile prosthetic heart valve for replacing a mitral valve
US10080653B2 (en) 2015-09-10 2018-09-25 Edwards Lifesciences Corporation Limited expansion heart valve
US10080652B2 (en) 2015-03-13 2018-09-25 Boston Scientific Scimed, Inc. Prosthetic heart valve having an improved tubular seal
US10098734B2 (en) 2013-12-05 2018-10-16 Edwards Lifesciences Corporation Prosthetic heart valve and delivery apparatus

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3197788A (en) * 1962-04-23 1965-08-03 Inst Of Medical Sciences Prosthetic valve for cardiac surgery
US3570014A (en) * 1968-09-16 1971-03-16 Warren D Hancock Stent for heart valve

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3197788A (en) * 1962-04-23 1965-08-03 Inst Of Medical Sciences Prosthetic valve for cardiac surgery
US3570014A (en) * 1968-09-16 1971-03-16 Warren D Hancock Stent for heart valve

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
Clinical Experience With Supported Homograft Heart Valve For Mitral and Aortic Valve Replacement by S. Sugie et al., The Journal of Thoracic & Cardiovascular Surgery, Vol. 57, No. 4. Apr. 1969, pp. 455 462. *
Heart Valve Replacement With Reinforced Aortic Heterografts by M. I. Fonescu et al. The Journal of Thoracic & Cardiovascular Surgery, Vol. 56, No. 3, Sept. 1968, pp. 333 348. *
Pig Aortic Valve as a Replacement for Mitral Valve in the Dog, by W. A. Reed et al., The Journal of Thoracic and Cardiovascular Surgery, Vol. 57, No. 5, May 1969, pp. 663 667. *

Cited By (569)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3983581A (en) * 1975-01-20 1976-10-05 William W. Angell Heart valve stent
US4035849A (en) * 1975-11-17 1977-07-19 William W. Angell Heart valve stent and process for preparing a stented heart valve prosthesis
US4106129A (en) * 1976-01-09 1978-08-15 American Hospital Supply Corporation Supported bioprosthetic heart valve with compliant orifice ring
US4084268A (en) * 1976-04-22 1978-04-18 Shiley Laboratories, Incorporated Prosthetic tissue heart valve
DE2807467A1 (en) * 1977-02-23 1978-08-24 Robert Bernard Davis Heart valve prosthesis
US4297749A (en) * 1977-04-25 1981-11-03 Albany International Corp. Heart valve prosthesis
US4218782A (en) * 1977-05-25 1980-08-26 Biocoating Anpartsselskab Heart valve prosthesis and method for the production thereof
US4265694A (en) * 1978-12-14 1981-05-05 The United States Of America As Represented By The Department Of Health, Education And Welfare Method of making unitized three leaflet heart valve
US4222126A (en) * 1978-12-14 1980-09-16 The United States Of America As Represented By The Secretary Of The Department Of Health, Education & Welfare Unitized three leaflet heart valve
US4259753A (en) * 1979-03-16 1981-04-07 Liotta Domingo S Frame support for cardiac tissue valves
FR2451189A1 (en) * 1979-03-16 1980-10-10 Liotta Domingo Support for the heart valves of biological tissues
US4343048A (en) * 1979-08-06 1982-08-10 Ross Donald N Stent for a cardiac valve
US4275469A (en) * 1979-12-13 1981-06-30 Shelhigh Inc. Prosthetic heart valve
US4340977A (en) * 1980-09-19 1982-07-27 Brownlee Richard T Catenary mitral valve replacement
EP0071610B1 (en) * 1981-02-04 1986-03-12 Institutul De Cercetari Veterinare Si Biopreparate "Pasteur" Cardiac valvular bioprosthesis and the method of manufacture thereof
US4470157A (en) * 1981-04-27 1984-09-11 Love Jack W Tricuspid prosthetic tissue heart valve
US4345340A (en) * 1981-05-07 1982-08-24 Vascor, Inc. Stent for mitral/tricuspid heart valve
US4816029A (en) * 1981-05-07 1989-03-28 Medtronic, Inc. Stent for aortic heart valve
FR2510396A1 (en) * 1981-07-28 1983-02-04 Extracorporeal Med Spec heart valve protection device
WO1983000617A1 (en) * 1981-08-17 1983-03-03 American Hospital Supply Corp Leaflet attachment and method of attachment for prosthetic heart valves
US4350492A (en) * 1981-08-24 1982-09-21 Vascor, Inc. Method for preparing tissue heart valve
US4865600A (en) * 1981-08-25 1989-09-12 Baxter International Inc. Mitral valve holder
US4364127A (en) * 1981-10-02 1982-12-21 Research Corporation Trileaflet type prosthetic heart valve
USRE42395E1 (en) * 1981-10-29 2011-05-24 Medtronic, Inc. Valve holder for tricuspid heart valve
US7018407B1 (en) 1981-10-29 2006-03-28 Medtronic Valve holder for tricuspid heart valve
US4451936A (en) * 1981-12-21 1984-06-05 American Hospital Supply Corporation Supra-annular aortic valve
WO1983002225A1 (en) * 1981-12-21 1983-07-07 American Hospital Supply Corp Supra-annular valve
US4490859A (en) * 1982-01-20 1985-01-01 University Of Sheffield Artificial heart valves
US4473423A (en) * 1982-05-03 1984-09-25 University Of Utah Artificial heart valve made by vacuum forming technique
US4510628A (en) * 1982-05-03 1985-04-16 University Of Utah Artificial heart valve made by vacuum forming technique
US4477930A (en) * 1982-09-28 1984-10-23 Mitral Medical International, Inc. Natural tissue heat valve and method of making same
US4556996A (en) * 1983-08-04 1985-12-10 Robert S. Wallace Heart valve
EP0143246A3 (en) * 1983-09-23 1986-02-05 Christian Weinhold Heart valve prosthesis
EP0143246A2 (en) * 1983-09-23 1985-06-05 Peter Kennedy Pty. Ltd. Heart valve prosthesis
EP0150608A1 (en) * 1983-12-28 1985-08-07 Shiley Inc. Stent covering for tissue valves
EP0155245A2 (en) * 1984-03-16 1985-09-18 SORIN BIOMEDICA S.p.A. Cardiac valve prosthesis with valve flaps of biological tissues
EP0155245A3 (en) * 1984-03-16 1987-05-13 Sorin Biomedica S.P.A. Cardiac valve prosthesis with valve flaps of biological tissues
US4759758A (en) * 1984-12-07 1988-07-26 Shlomo Gabbay Prosthetic heart valve
DE3608435A1 (en) * 1986-03-06 1987-09-24 Mo Vysshee Tekhnicheskoe Uchil Biological heart valve prosthesis
US4692164A (en) * 1986-03-06 1987-09-08 Moskovskoe Vysshee Tekhnicheskoe Uchilische, Imeni N.E. Baumana Bioprosthetic heart valve, methods and device for preparation thereof
GB2230077A (en) * 1987-07-31 1990-10-10 Pacific Biomedical Holdings Bioprosthetic valve stent
GB2230077B (en) * 1987-07-31 1992-02-19 Pacific Biomedical Holdings Bioprosthetic valve stent
WO1989000840A1 (en) * 1987-07-31 1989-02-09 Pacific Biomedical Holdings, Ltd. Bioprosthetic valve stent
US4851000A (en) * 1987-07-31 1989-07-25 Pacific Biomedical Holdings, Ltd. Bioprosthetic valve stent
US4932965A (en) * 1988-12-19 1990-06-12 Phillips Steven J Artificial valve, and needle and suture holder and method of using same
WO1990011738A1 (en) * 1989-04-05 1990-10-18 Alexander Bernhard Heart valve prosthesis for replacement of the aortic valve
US5840081A (en) * 1990-05-18 1998-11-24 Andersen; Henning Rud System and method for implanting cardiac valves
US6168614B1 (en) 1990-05-18 2001-01-02 Heartport, Inc. Valve prosthesis for implantation in the body
US6582462B1 (en) 1990-05-18 2003-06-24 Heartport, Inc. Valve prosthesis for implantation in the body and a catheter for implanting such valve prosthesis
US7789909B2 (en) 1990-05-18 2010-09-07 Edwards Lifesciences Ag System for implanting a valve prosthesis
US7618446B2 (en) 1990-05-18 2009-11-17 Edwards Lifesciences Ag Valve prosthesis for implantation in the body and a catheter for implanting such valve prosthesis
WO1992009247A1 (en) * 1990-11-29 1992-06-11 Anschütz & Co. Gmbh Support ring for a biological aortic-valve prosthesis
US5489298A (en) * 1991-01-24 1996-02-06 Autogenics Rapid assembly concentric mating stent, tissue heart valve with enhanced clamping and tissue exposure
US5653749A (en) * 1991-01-24 1997-08-05 Autogenics Prefabricated, sterile and disposable kits for the rapid assembly of a tissue heart valve
US5423887A (en) * 1991-01-24 1995-06-13 Autogenics Rapid assembly, concentric mating stent, tissue heart valve with enhanced clamping and tissue alignment
US5531784A (en) * 1991-01-24 1996-07-02 Autogenics Test device for and method of testing rapid assembly tissue heart valve
US5326370A (en) * 1991-01-24 1994-07-05 Autogenics Prefabricated sterile and disposable kits for the rapid assembly of a tissue heart valve
US5571174A (en) * 1991-01-24 1996-11-05 Autogenics Method of assembling a tissue heart valve
US5584878A (en) * 1991-01-24 1996-12-17 Autogenics Test device for and method of testing rapid tissue heart valve
US5326371A (en) * 1991-01-24 1994-07-05 Autogenics Rapid assembly, concentric mating stent, tissue heart valve with enhanced clamping and tissue alignment
US5163955A (en) * 1991-01-24 1992-11-17 Autogenics Rapid assembly, concentric mating stent, tissue heart valve with enhanced clamping and tissue alignment
US5662705A (en) * 1991-01-24 1997-09-02 Autogenics Test device for and method of testing rapid assembly tissue heart valve
US5755782A (en) * 1991-01-24 1998-05-26 Autogenics Stents for autologous tissue heart valve
US5606928A (en) * 1991-05-08 1997-03-04 Nika Health Products Limited Process and apparatus for the production of a heart valve prosthesis
US5449385A (en) * 1991-05-08 1995-09-12 Nika Health Products Limited Support for a heart valve prosthesis
WO1992019185A1 (en) * 1991-05-08 1992-11-12 Nika Health Products Limited Process and apparatus for the production of a heart valve prosthesis
US5488789A (en) * 1991-05-08 1996-02-06 Nika Health Products Limited Process and apparatus for the production of a heart valve prosthesis
US20040236418A1 (en) * 1991-07-16 2004-11-25 Stevens John H. Endovascular aortic valve replacement
US5792094A (en) * 1991-07-16 1998-08-11 Heartport, Inc. Method of delivering cardioplegic fluid to a patient's heart
US8915959B2 (en) 1991-07-16 2014-12-23 Heartport, Inc. Endovascular aortic valve replacement
US6482171B1 (en) 1991-07-16 2002-11-19 Heartport, Inc. Multi-lumen catheter
US6338735B1 (en) 1991-07-16 2002-01-15 John H. Stevens Methods for removing embolic material in blood flowing through a patient's ascending aorta
US20020058995A1 (en) * 1991-07-16 2002-05-16 Stevens John H. Endovascular aortic valve replacement
WO1994001060A1 (en) * 1992-07-10 1994-01-20 Adiam Medizintechnik Gmbh & Co. Kg Support housing for valve and closure members
US20040088045A1 (en) * 1993-11-01 2004-05-06 3F Therapeutics, Inc. Replacement heart valve
US5609600A (en) * 1993-12-17 1997-03-11 Autogenics Tissue cutting die
US5612885A (en) * 1993-12-17 1997-03-18 Autogenics Method for constructing a heart valve stent
US5425741A (en) * 1993-12-17 1995-06-20 Autogenics Tissue cutting die
US5588967A (en) * 1993-12-17 1996-12-31 Autogenics, Inc. Tissue cutting die
US5810757A (en) * 1994-05-27 1998-09-22 Heartport, Inc. Catheter system and method for total isolation of the heart
US5765568A (en) * 1994-05-27 1998-06-16 Heartport, Inc. Catheter system and method for venting the left ventricle
US5800375A (en) * 1994-05-27 1998-09-01 Heartport, Inc. Catheter system and method for providing cardiopulmonary bypass pump support during heart surgery
US6398752B1 (en) 1994-05-27 2002-06-04 William P. Sweezer, Jr. Method of occluding a patient's ascending aorta and delivery cardioplegic fluid
US5562729A (en) * 1994-11-01 1996-10-08 Biocontrol Technology, Inc. Heart valve
US9486312B2 (en) 1996-12-31 2016-11-08 Edwards Lifesciences Pvt, Inc. Method of manufacturing a prosthetic valve
US9095432B2 (en) 1996-12-31 2015-08-04 Edwards Lifesciences Pvt, Inc. Collapsible prosthetic valve having an internal cover
US20080077236A1 (en) * 1996-12-31 2008-03-27 Brice Letac Valve prosthesis for implantation in body channels
US20080009940A1 (en) * 1996-12-31 2008-01-10 Alain Cribier Valve prosthesis for implantation in body channels
US7846204B2 (en) 1996-12-31 2010-12-07 Edwards Lifesciences Pvt, Inc. Aortic valve prosthesis having natural tissue and an internal cover
US7846203B2 (en) 1996-12-31 2010-12-07 Edwards Lifesciences Pvt, Inc. Implanting a stent valve prosthesis at the native aortic valve
US20090132032A9 (en) * 1996-12-31 2009-05-21 Alain Cribier Valve prosthesis for implantation in body channels
US8002825B2 (en) 1996-12-31 2011-08-23 Edwards Lifesciences Pvt, Inc. Implantable prosthetic valve for treating aortic stenosis
US8591575B2 (en) 1996-12-31 2013-11-26 Edwards Lifesciences Pvt, Inc. Method of dilating a stenotic aortic valve and implanting a prosthetic valve
US20030109924A1 (en) * 1996-12-31 2003-06-12 Alain Cribier Implanting a valve prosthesis in body channels
US7585321B2 (en) 1996-12-31 2009-09-08 Edwards Lifesciences Pvt, Inc. Methods of implanting a prosthetic heart valve within a native heart valve
US20050203616A1 (en) * 1996-12-31 2005-09-15 Alain Cribier Valve prosthesis for implantation in body channels
US8057540B2 (en) 1996-12-31 2011-11-15 Edwards Lifesciences Pvt, Inc. Method of treating aortic stenosis using an implantable prosthetic valve
US9629714B2 (en) 1996-12-31 2017-04-25 Edwards Lifesciences Pvt, Inc. Collapsible prosthetic valve
US20110087322A1 (en) * 1996-12-31 2011-04-14 Edwards Lifesciences Pvt, Inc. Method of Treating Aortic Stenosis Using an Implantable Prosthetic Valve
EP2263609B1 (en) 1996-12-31 2016-01-13 Edwards Lifesciences PVT, Inc. Method of manufacturing a prosthetic valve assembly
US20060009842A1 (en) * 1997-03-27 2006-01-12 Huynh Van L Contoured heart valve suture rings
US6585766B1 (en) 1997-03-27 2003-07-01 Edwards Lifesciences Corporation Cloth-covered stents for tissue heart valves
US6102944A (en) * 1997-03-27 2000-08-15 Edwards Lifesciences Corporation Methods of tissue heart valve assembly
US8518108B2 (en) 1997-03-27 2013-08-27 Edwards Lifesciences Corporation Contoured heart valve suture rings
US5928281A (en) * 1997-03-27 1999-07-27 Baxter International Inc. Tissue heart valves
US6423031B1 (en) 1997-04-01 2002-07-23 Brian S. Donlon Methods and devices for occluding a patient's ascending aorta
US6056723A (en) * 1997-04-01 2000-05-02 Heartport, Inc. Methods and devices for occluding a patient's ascending aorta
US5755687A (en) * 1997-04-01 1998-05-26 Heartport, Inc. Methods and devices for occluding a patient's ascending aorta
US6565603B2 (en) 1998-06-16 2003-05-20 Cardiac Concepts, Inc. Mitral valve annuloplasty ring
US6250308B1 (en) 1998-06-16 2001-06-26 Cardiac Concepts, Inc. Mitral valve annuloplasty ring and method of implanting
US6334873B1 (en) 1998-09-28 2002-01-01 Autogenics Heart valve having tissue retention with anchors and an outer sheath
US20020151970A1 (en) * 1999-02-10 2002-10-17 Garrison Michi E. Methods and devices for implanting cardiac valves
US6231602B1 (en) 1999-04-16 2001-05-15 Edwards Lifesciences Corporation Aortic annuloplasty ring
WO2000062715A1 (en) * 1999-04-16 2000-10-26 Edwards Lifesciences Corporation Aortic annuloplasty ring
US20030044596A1 (en) * 1999-10-19 2003-03-06 Lazarov Miladin P. Biocompatible article
WO2001030275A1 (en) * 1999-10-29 2001-05-03 Fundacja Rozwoju Kardiochirurgii Heart valve stent, in particular mitral heart valve stent
US7018406B2 (en) 1999-11-17 2006-03-28 Corevalve Sa Prosthetic valve for transluminal delivery
USRE45865E1 (en) 1999-11-17 2016-01-26 Medtronic Corevalve Llc Prosthetic valve for transluminal delivery
US8721708B2 (en) 1999-11-17 2014-05-13 Medtronic Corevalve Llc Prosthetic valve for transluminal delivery
US8801779B2 (en) 1999-11-17 2014-08-12 Medtronic Corevalve, Llc Prosthetic valve for transluminal delivery
US8603159B2 (en) 1999-11-17 2013-12-10 Medtronic Corevalve, Llc Prosthetic valve for transluminal delivery
US8876896B2 (en) 1999-11-17 2014-11-04 Medtronic Corevalve Llc Prosthetic valve for transluminal delivery
US8998979B2 (en) 1999-11-17 2015-04-07 Medtronic Corevalve Llc Transcatheter heart valves
US7329278B2 (en) 1999-11-17 2008-02-12 Corevalve, Inc. Prosthetic valve for transluminal delivery
US9060856B2 (en) 1999-11-17 2015-06-23 Medtronic Corevalve Llc Transcatheter heart valves
US8986329B2 (en) 1999-11-17 2015-03-24 Medtronic Corevalve Llc Methods for transluminal delivery of prosthetic valves
US20060129235A1 (en) * 1999-11-17 2006-06-15 Jacques Seguin Prosthetic valve for transluminal delivery
US8579966B2 (en) 1999-11-17 2013-11-12 Medtronic Corevalve Llc Prosthetic valve for transluminal delivery
US9962258B2 (en) 1999-11-17 2018-05-08 Medtronic CV Luxembourg S.a.r.l. Transcatheter heart valves
US7892281B2 (en) 1999-11-17 2011-02-22 Medtronic Corevalve Llc Prosthetic valve for transluminal delivery
US20080133003A1 (en) * 1999-11-17 2008-06-05 Jacques Seguin Prosthetic valve for transluminal delivery
US9066799B2 (en) 1999-11-17 2015-06-30 Medtronic Corevalve Llc Prosthetic valve for transluminal delivery
US8016877B2 (en) 1999-11-17 2011-09-13 Medtronic Corevalve Llc Prosthetic valve for transluminal delivery
US9949831B2 (en) 2000-01-19 2018-04-24 Medtronics, Inc. Image-guided heart valve placement
US8241274B2 (en) 2000-01-19 2012-08-14 Medtronic, Inc. Method for guiding a medical device
US20040049262A1 (en) * 2000-01-31 2004-03-11 Obermiller Joseph F. Stent valves and uses of same
US20080154356A1 (en) * 2000-01-31 2008-06-26 Obermiller Joseph F Percutaneous heart valve devices
US20050096736A1 (en) * 2000-01-31 2005-05-05 Osse Francisco J. Percutaneous heart valve devices
US8906083B2 (en) 2000-01-31 2014-12-09 Cook Biotech Incorporated Stent valves and uses of same
WO2001062189A1 (en) * 2000-02-28 2001-08-30 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Device for fastening and anchoring cardiac valve prostheses
USRE45130E1 (en) 2000-02-28 2014-09-09 Jenavalve Technology Gmbh Device for fastening and anchoring cardiac valve prostheses
US20140222140A1 (en) * 2000-04-06 2014-08-07 Edwards Lifesciences Corporation Methods of implanting minimally-invasive prosthetic heart valves
US6767362B2 (en) 2000-04-06 2004-07-27 Edwards Lifesciences Corporation Minimally-invasive heart valves and methods of use
US6454799B1 (en) * 2000-04-06 2002-09-24 Edwards Lifesciences Corporation Minimally-invasive heart valves and methods of use
US7381218B2 (en) 2000-04-06 2008-06-03 Edwards Lifesciences Corporation System and method for implanting a two-part prosthetic heart valve
US10022220B2 (en) * 2000-04-06 2018-07-17 Edwards Lifesciences Corporation Methods of implanting minimally-invasive prosthetic heart valves
US8349000B2 (en) 2000-04-06 2013-01-08 Edwards Lifesciences Corporation Minimally-invasive heart valves
US20040186565A1 (en) * 2000-04-06 2004-09-23 Stefan Schreck Minimally-invasive heart valves with wireforms
US20100211165A1 (en) * 2000-04-06 2010-08-19 Stefan Schreck Minimally-invasive heart valves
US8092518B2 (en) 2000-04-06 2012-01-10 Edwards Lifesciences Corporation Methods of implanting two-part heart valves
US9439762B2 (en) 2000-06-01 2016-09-13 Edwards Lifesciences Corporation Methods of implant of a heart valve with a convertible sewing ring
US7758606B2 (en) 2000-06-30 2010-07-20 Medtronic, Inc. Intravascular filter with debris entrapment mechanism
US8777980B2 (en) 2000-06-30 2014-07-15 Medtronic, Inc. Intravascular filter with debris entrapment mechanism
US8092487B2 (en) 2000-06-30 2012-01-10 Medtronic, Inc. Intravascular filter with debris entrapment mechanism
US7819915B2 (en) 2000-07-27 2010-10-26 Edwards Lifesciences Corporation Heart valve holders and handling clips therefor
US6635085B1 (en) * 2000-08-17 2003-10-21 Carbomedics Inc. Heart valve stent with alignment posts
US7179290B2 (en) 2000-09-22 2007-02-20 Edwards Lifesciences Flexible heart valve
US6461382B1 (en) 2000-09-22 2002-10-08 Edwards Lifesciences Corporation Flexible heart valve having moveable commissures
US20050096739A1 (en) * 2000-09-22 2005-05-05 Dongbu Cao Flexible heart valve
US20030014105A1 (en) * 2000-09-22 2003-01-16 Dongbu Cao Flexible heart valve leaflets with concave free edges
US9241788B2 (en) 2001-03-23 2016-01-26 Edwards Lifesciences Corporation Method for treating an aortic valve
US9707074B2 (en) 2001-03-23 2017-07-18 Edwards Lifesciences Corporation Method for treating an aortic valve
US8206438B2 (en) 2001-03-23 2012-06-26 Edwards Lifesciences Corporation Prosthetic heart valve having flared outflow section
US8623077B2 (en) 2001-06-29 2014-01-07 Medtronic, Inc. Apparatus for replacing a cardiac valve
US7544206B2 (en) 2001-06-29 2009-06-09 Medtronic, Inc. Method and apparatus for resecting and replacing an aortic valve
US8771302B2 (en) 2001-06-29 2014-07-08 Medtronic, Inc. Method and apparatus for resecting and replacing an aortic valve
US8956402B2 (en) 2001-06-29 2015-02-17 Medtronic, Inc. Apparatus for replacing a cardiac valve
US8070801B2 (en) 2001-06-29 2011-12-06 Medtronic, Inc. Method and apparatus for resecting and replacing an aortic valve
US7780726B2 (en) 2001-07-04 2010-08-24 Medtronic, Inc. Assembly for placing a prosthetic valve in a duct in the body
US7252682B2 (en) 2001-07-04 2007-08-07 Corevalve, S.A. Kit enabling a prosthetic valve to be placed in a body enabling a prosthetic valve to be put into place in a duct in the body
US9149357B2 (en) 2001-07-04 2015-10-06 Medtronic CV Luxembourg S.a.r.l. Heart valve assemblies
US8002826B2 (en) 2001-07-04 2011-08-23 Medtronic Corevalve Llc Assembly for placing a prosthetic valve in a duct in the body
US20050043790A1 (en) * 2001-07-04 2005-02-24 Jacques Seguin Kit enabling a prosthetic valve to be placed in a body enabling a prosthetic valve to be put into place in a duct in the body
US8628570B2 (en) 2001-07-04 2014-01-14 Medtronic Corevalve Llc Assembly for placing a prosthetic valve in a duct in the body
US20050033398A1 (en) * 2001-07-31 2005-02-10 Jacques Seguin Assembly for setting a valve prosthesis in a corporeal duct
US7682390B2 (en) 2001-07-31 2010-03-23 Medtronic, Inc. Assembly for setting a valve prosthesis in a corporeal duct
US7611535B2 (en) 2001-09-07 2009-11-03 Medtronic, Inc. Fixation band for affixing a prosthetic heart valve to tissue
US9539088B2 (en) 2001-09-07 2017-01-10 Medtronic, Inc. Fixation band for affixing a prosthetic heart valve to tissue
US9539091B2 (en) 2001-09-13 2017-01-10 Edwards Lifesciences Corporation Methods and apparatuses for deploying minimally-invasive heart valves
US9572664B2 (en) 2001-09-13 2017-02-21 Edwards Lifesciences Corporation Methods and apparatuses for deploying minimally-invasive heart valves
US9848985B2 (en) 2001-09-13 2017-12-26 Edwards Lifesciences Corporation Methods and apparatuses for deploying minimally-invasive heart valves
US9572663B2 (en) 2001-09-13 2017-02-21 Edwards Lifesciences Corporation Methods and apparatuses for deploying minimally-invasive heart valves
US9452046B2 (en) 2001-09-13 2016-09-27 Edwards Lifesciences Corporation Methods and apparatuses for deploying minimally-invasive heart valves
US9168136B2 (en) 2001-09-13 2015-10-27 Edwards Lifesciences Corporation Methods for deploying self-expanding heart valves
US9937039B2 (en) 2001-10-11 2018-04-10 Edwards Lifesciences Pvt, Inc. Prosthetic heart valve and method
US20050192665A1 (en) * 2001-10-11 2005-09-01 Benjamin Spenser Implantable prosthetic valve
US20040039436A1 (en) * 2001-10-11 2004-02-26 Benjamin Spenser Implantable prosthetic valve
US9132006B2 (en) 2001-10-11 2015-09-15 Edwards Lifesciences Pvt, Inc. Prosthetic heart valve and method
US7393360B2 (en) 2001-10-11 2008-07-01 Edwards Lifesciences Pvt, Inc. Implantable prosthetic valve
US9629717B2 (en) 2001-10-11 2017-04-25 Edwards Lifesciences Pvt, Inc. Prosthetic heart valve and method
US10052203B2 (en) 2001-10-11 2018-08-21 Edwards Lifesciences Pvt, Inc. Prosthetic heart valve and method
US7510575B2 (en) 2001-10-11 2009-03-31 Edwards Lifesciences Corporation Implantable prosthetic valve
US9339383B2 (en) 2001-10-11 2016-05-17 Edwards Lifesciences Pvt, Inc. Prosthetic heart valve and method
US7972377B2 (en) 2001-12-27 2011-07-05 Medtronic, Inc. Bioprosthetic heart valve
US7201771B2 (en) 2001-12-27 2007-04-10 Arbor Surgical Technologies, Inc. Bioprosthetic heart valve
US20030167089A1 (en) * 2001-12-27 2003-09-04 Ernest Lane Bioprosthetic heart valve
US7033390B2 (en) 2002-01-02 2006-04-25 Medtronic, Inc. Prosthetic heart valve system
US20030125805A1 (en) * 2002-01-02 2003-07-03 Medtronic, Inc. Heart valve system
US7189258B2 (en) 2002-01-02 2007-03-13 Medtronic, Inc. Heart valve system
US20090198323A1 (en) * 2002-01-02 2009-08-06 Johnson Keith M Prosthetic Heart Valve System
US20060235510A1 (en) * 2002-01-02 2006-10-19 Johnson Keith M Prosthetic heart valve system
US20060195181A1 (en) * 2002-01-02 2006-08-31 Johnson Keith M Heart valve system
US7468073B2 (en) 2002-01-02 2008-12-23 Medtronic, Inc. Heart valve system
US8029564B2 (en) 2002-01-02 2011-10-04 Medtronic, Inc. Prosthetic heart valve system
US20040024451A1 (en) * 2002-01-02 2004-02-05 Medtronic, Inc. Prosthetic heart valve system
US7503929B2 (en) 2002-01-02 2009-03-17 Medtronic, Inc. Prosthetic heart valve system
US8858619B2 (en) 2002-04-23 2014-10-14 Medtronic, Inc. System and method for implanting a replacement valve
US8721713B2 (en) 2002-04-23 2014-05-13 Medtronic, Inc. System for implanting a replacement valve
US8349003B2 (en) 2002-07-16 2013-01-08 Medtronic, Inc. Suture locking assembly and method of use
US7959674B2 (en) 2002-07-16 2011-06-14 Medtronic, Inc. Suture locking assembly and method of use
US7182788B2 (en) 2002-09-03 2007-02-27 M. I. Tech Co., Ltd. Stent and method for manufacturing the same
EP1430853A2 (en) 2002-09-03 2004-06-23 M.I. Tech Co., Ltd. Stent and method for manufacturing the same
US20040044402A1 (en) * 2002-09-03 2004-03-04 M.I. Tech Co., Ltd. Stent and method for manufacturing the same
US20040122514A1 (en) * 2002-12-20 2004-06-24 Fogarty Thomas J. Biologically implantable prosthesis and methods of using the same
US8551162B2 (en) 2002-12-20 2013-10-08 Medtronic, Inc. Biologically implantable prosthesis
US8623080B2 (en) 2002-12-20 2014-01-07 Medtronic, Inc. Biologically implantable prosthesis and methods of using the same
US8460373B2 (en) 2002-12-20 2013-06-11 Medtronic, Inc. Method for implanting a heart valve within an annulus of a patient
US8025695B2 (en) * 2002-12-20 2011-09-27 Medtronic, Inc. Biologically implantable heart valve system
US7981153B2 (en) 2002-12-20 2011-07-19 Medtronic, Inc. Biologically implantable prosthesis methods of using
US9333078B2 (en) 2002-12-20 2016-05-10 Medtronic, Inc. Heart valve assemblies
US7147640B2 (en) 2003-03-12 2006-12-12 Acumed Llc External fixator
US9504567B2 (en) 2003-03-18 2016-11-29 Edwards Lifesciences Corporation Minimally-invasive prosthetic heart valve method
US20040186563A1 (en) * 2003-03-18 2004-09-23 Lobbi Mario M. Minimally-invasive heart valve with cusp positioners
US9320598B2 (en) 2003-03-18 2016-04-26 Edwards Lifesciences Corporation Method of implanting a self-expandable prosthetic heart valve
US7399315B2 (en) 2003-03-18 2008-07-15 Edwards Lifescience Corporation Minimally-invasive heart valve with cusp positioners
US9675455B2 (en) 2003-03-18 2017-06-13 Edwards Lifesciences Corporation Method of positioning a minimally-invasive heart valve with cusp positioners
US9724193B2 (en) 2003-03-18 2017-08-08 Edwards Lifesciences Corporation Self-expandable heart valve with stabilizers
US8778018B2 (en) 2003-03-18 2014-07-15 Mario M. Iobbi Method of implanting a minimally-invasive heart valve with cusp positioners
US8747463B2 (en) 2003-08-22 2014-06-10 Medtronic, Inc. Methods of using a prosthesis fixturing device
US8021421B2 (en) 2003-08-22 2011-09-20 Medtronic, Inc. Prosthesis heart valve fixturing device
US20080275549A1 (en) * 2003-10-02 2008-11-06 Edwards Lifesciences Pvt, Inc. Implantable prosthetic valve with non-laminar flow
US8080054B2 (en) 2003-10-02 2011-12-20 Edwards Lifesciences Corporation Implantable prosthetic valve with non-laminar flow
US9241793B2 (en) 2003-10-02 2016-01-26 Edwards Lifesciences Corporation Method of implanting a prosthetic aortic valve having non-laminar flow
US8603161B2 (en) 2003-10-08 2013-12-10 Medtronic, Inc. Attachment device and methods of using the same
WO2005065594A1 (en) * 2003-12-19 2005-07-21 Boston Scientific Limited Venous valve apparatus, system, and method
US8721717B2 (en) 2003-12-19 2014-05-13 Boston Scientific Scimed, Inc. Venous valve apparatus, system, and method
US8128681B2 (en) * 2003-12-19 2012-03-06 Boston Scientific Scimed, Inc. Venous valve apparatus, system, and method
US8840663B2 (en) 2003-12-23 2014-09-23 Sadra Medical, Inc. Repositionable heart valve method
US9956075B2 (en) 2003-12-23 2018-05-01 Boston Scientific Scimed Inc. Methods and apparatus for endovascularly replacing a heart valve
US8246678B2 (en) 2003-12-23 2012-08-21 Sadra Medicl, Inc. Methods and apparatus for endovascularly replacing a patient's heart valve
US8182528B2 (en) 2003-12-23 2012-05-22 Sadra Medical, Inc. Locking heart valve anchor
US8894703B2 (en) 2003-12-23 2014-11-25 Sadra Medical, Inc. Systems and methods for delivering a medical implant
US9585750B2 (en) 2003-12-23 2017-03-07 Boston Scientific Scimed, Inc. Methods and apparatus for endovascularly replacing a patient's heart valve
US9585749B2 (en) 2003-12-23 2017-03-07 Boston Scientific Scimed, Inc. Replacement heart valve assembly
US8603160B2 (en) 2003-12-23 2013-12-10 Sadra Medical, Inc. Method of using a retrievable heart valve anchor with a sheath
US9277991B2 (en) 2003-12-23 2016-03-08 Boston Scientific Scimed, Inc. Low profile heart valve and delivery system
US9308085B2 (en) 2003-12-23 2016-04-12 Boston Scientific Scimed, Inc. Repositionable heart valve and method
US8231670B2 (en) 2003-12-23 2012-07-31 Sadra Medical, Inc. Repositionable heart valve and method
US8343213B2 (en) 2003-12-23 2013-01-01 Sadra Medical, Inc. Leaflet engagement elements and methods for use thereof
US9320599B2 (en) 2003-12-23 2016-04-26 Boston Scientific Scimed, Inc. Methods and apparatus for endovascularly replacing a heart valve
US9358110B2 (en) 2003-12-23 2016-06-07 Boston Scientific Scimed, Inc. Medical devices and delivery systems for delivering medical devices
US8052749B2 (en) 2003-12-23 2011-11-08 Sadra Medical, Inc. Methods and apparatus for endovascular heart valve replacement comprising tissue grasping elements
US8858620B2 (en) 2003-12-23 2014-10-14 Sadra Medical Inc. Methods and apparatus for endovascularly replacing a heart valve
US9005273B2 (en) 2003-12-23 2015-04-14 Sadra Medical, Inc. Assessing the location and performance of replacement heart valves
US9358106B2 (en) 2003-12-23 2016-06-07 Boston Scientific Scimed Inc. Methods and apparatus for performing valvuloplasty
US9393113B2 (en) 2003-12-23 2016-07-19 Boston Scientific Scimed Inc. Retrievable heart valve anchor and method
US9861476B2 (en) 2003-12-23 2018-01-09 Boston Scientific Scimed Inc. Leaflet engagement elements and methods for use thereof
US8840662B2 (en) 2003-12-23 2014-09-23 Sadra Medical, Inc. Repositionable heart valve and method
US8623078B2 (en) 2003-12-23 2014-01-07 Sadra Medical, Inc. Replacement valve and anchor
US8623076B2 (en) 2003-12-23 2014-01-07 Sadra Medical, Inc. Low profile heart valve and delivery system
US9526609B2 (en) 2003-12-23 2016-12-27 Boston Scientific Scimed, Inc. Methods and apparatus for endovascularly replacing a patient's heart valve
US20070162107A1 (en) 2003-12-23 2007-07-12 Sadra Medical, Inc. Methods and apparatus for endovascularly replacing a patient's heart valve
US8828078B2 (en) 2003-12-23 2014-09-09 Sadra Medical, Inc. Methods and apparatus for endovascular heart valve replacement comprising tissue grasping elements
US8579962B2 (en) 2003-12-23 2013-11-12 Sadra Medical, Inc. Methods and apparatus for performing valvuloplasty
US9532872B2 (en) 2003-12-23 2017-01-03 Boston Scientific Scimed, Inc. Systems and methods for delivering a medical implant
US9872768B2 (en) 2003-12-23 2018-01-23 Boston Scientific Scimed, Inc. Medical devices and delivery systems for delivering medical devices
US9011521B2 (en) 2003-12-23 2015-04-21 Sadra Medical, Inc. Methods and apparatus for endovascularly replacing a patient's heart valve
US8252052B2 (en) 2003-12-23 2012-08-28 Sadra Medical, Inc. Methods and apparatus for endovascularly replacing a patient's heart valve
US10085836B2 (en) 2004-01-23 2018-10-02 Edwards Lifesciences Corporation Prosthetic mitral valve
US20160158013A1 (en) * 2004-01-23 2016-06-09 Edwards Lifesciences Corporation Prosthetic mitral valve
US9155617B2 (en) 2004-01-23 2015-10-13 Edwards Lifesciences Corporation Prosthetic mitral valve
US9730794B2 (en) * 2004-01-23 2017-08-15 Edwards Lifesciences Corporation Prosthetic mitral valve
US8128692B2 (en) 2004-02-27 2012-03-06 Aortx, Inc. Prosthetic heart valves, scaffolding structures, and systems and methods for implantation of same
US8728156B2 (en) 2004-02-27 2014-05-20 Cardiac MD, Inc. Prosthetic heart valves, scaffolding structures, and systems and methods for implantation of same
US9168134B2 (en) 2004-02-27 2015-10-27 Cardiacmd, Inc. Method for delivering a prosthetic heart valve with an expansion member
US8430925B2 (en) 2004-02-27 2013-04-30 Cardiacmd, Inc. Prosthetic heart valves, scaffolding structures, and systems and methods for implantation of same
US7785341B2 (en) 2004-02-27 2010-08-31 Aortx, Inc. Prosthetic heart valves, scaffolding structures, and systems and methods for implantation of same
US8608770B2 (en) 2004-02-27 2013-12-17 Cardiacmd, Inc. Prosthetic heart valves, scaffolding structures, and systems and methods for implantation of same
US8535373B2 (en) 2004-03-03 2013-09-17 Sorin Group Italia S.R.L. Minimally-invasive cardiac-valve prosthesis
US8109996B2 (en) 2004-03-03 2012-02-07 Sorin Biomedica Cardio, S.R.L. Minimally-invasive cardiac-valve prosthesis
US20050197695A1 (en) * 2004-03-03 2005-09-08 Sorin Biomedica Cardio S.R.L. Minimally-invasive cardiac-valve prosthesis
US9867695B2 (en) 2004-03-03 2018-01-16 Sorin Group Italia S.R.L. Minimally-invasive cardiac-valve prosthesis
US8216299B2 (en) 2004-04-01 2012-07-10 Cook Medical Technologies Llc Method to retract a body vessel wall with remodelable material
US7637937B2 (en) 2004-04-08 2009-12-29 Cook Incorporated Implantable medical device with optimized shape
US9775704B2 (en) 2004-04-23 2017-10-03 Medtronic3F Therapeutics, Inc. Implantable valve prosthesis
US8668733B2 (en) 2004-06-16 2014-03-11 Sadra Medical, Inc. Everting heart valve
US9744035B2 (en) 2004-06-16 2017-08-29 Boston Scientific Scimed, Inc. Everting heart valve
US8992608B2 (en) 2004-06-16 2015-03-31 Sadra Medical, Inc. Everting heart valve
US7276078B2 (en) * 2004-06-30 2007-10-02 Edwards Lifesciences Pvt Paravalvular leak detection, sealing, and prevention
US7462191B2 (en) 2004-06-30 2008-12-09 Edwards Lifesciences Pvt, Inc. Device and method for assisting in the implantation of a prosthetic valve
US20060004439A1 (en) * 2004-06-30 2006-01-05 Benjamin Spenser Device and method for assisting in the implantation of a prosthetic valve
US7628805B2 (en) 2004-06-30 2009-12-08 Edwards Lifesciences Pvt, Inc. Paravalvular leak detection, sealing and prevention
US20060004442A1 (en) * 2004-06-30 2006-01-05 Benjamin Spenser Paravalvular leak detection, sealing, and prevention
US8734506B2 (en) 2004-07-19 2014-05-27 Coroneo, Inc. Aortic annuloplasty ring
US20060015179A1 (en) * 2004-07-19 2006-01-19 Neil Bulman-Fleming Aortic annuloplasty ring
US8034102B2 (en) 2004-07-19 2011-10-11 Coroneo, Inc. Aortic annuloplasty ring
US9089424B2 (en) 2004-07-19 2015-07-28 Coroneo, Inc. Aortic annuloplasty ring
US9480556B2 (en) 2004-09-07 2016-11-01 Medtronic, Inc. Replacement prosthetic heart valve, system and method of implant
US8591570B2 (en) 2004-09-07 2013-11-26 Medtronic, Inc. Prosthetic heart valve for replacing previously implanted heart valve
US6951571B1 (en) 2004-09-30 2005-10-04 Rohit Srivastava Valve implanting device
US8328868B2 (en) 2004-11-05 2012-12-11 Sadra Medical, Inc. Medical devices and delivery systems for delivering medical devices
US8617236B2 (en) 2004-11-05 2013-12-31 Sadra Medical, Inc. Medical devices and delivery systems for delivering medical devices
US9498329B2 (en) 2004-11-19 2016-11-22 Medtronic, Inc. Apparatus for treatment of cardiac valves and method of its manufacture
US8562672B2 (en) 2004-11-19 2013-10-22 Medtronic, Inc. Apparatus for treatment of cardiac valves and method of its manufacture
US20070219630A1 (en) * 2004-11-24 2007-09-20 Xi Chu Devices and Methods for Beating Heart Cardiac Surgeries
US8540768B2 (en) 2005-02-10 2013-09-24 Sorin Group Italia S.R.L. Cardiac valve prosthesis
US8920492B2 (en) 2005-02-10 2014-12-30 Sorin Group Italia S.R.L. Cardiac valve prosthesis
US9895223B2 (en) 2005-02-10 2018-02-20 Sorin Group Italia S.R.L. Cardiac valve prosthesis
US8539662B2 (en) 2005-02-10 2013-09-24 Sorin Group Italia S.R.L. Cardiac-valve prosthesis
US9486313B2 (en) 2005-02-10 2016-11-08 Sorin Group Italia S.R.L. Cardiac valve prosthesis
US8574257B2 (en) 2005-02-10 2013-11-05 Edwards Lifesciences Corporation System, device, and method for providing access in a cardiovascular environment
US8500802B2 (en) 2005-04-08 2013-08-06 Medtronic, Inc. Two-piece prosthetic valves with snap-in connection and methods for use
US7951197B2 (en) 2005-04-08 2011-05-31 Medtronic, Inc. Two-piece prosthetic valves with snap-in connection and methods for use
US9649495B2 (en) 2005-04-25 2017-05-16 Cardiac Pacemakers, Inc. Method and apparatus for pacing during revascularization
US9415225B2 (en) 2005-04-25 2016-08-16 Cardiac Pacemakers, Inc. Method and apparatus for pacing during revascularization
US9060857B2 (en) 2005-05-13 2015-06-23 Medtronic Corevalve Llc Heart valve prosthesis and methods of manufacture and use
US7914569B2 (en) 2005-05-13 2011-03-29 Medtronics Corevalve Llc Heart valve prosthesis and methods of manufacture and use
US20060259136A1 (en) * 2005-05-13 2006-11-16 Corevalve Sa Heart valve prosthesis and methods of manufacture and use
US20060265056A1 (en) * 2005-05-13 2006-11-23 Corevalve, Inc. Heart valve prosthesis and methods of manufacture and use
US8226710B2 (en) 2005-05-13 2012-07-24 Medtronic Corevalve, Inc. Heart valve prosthesis and methods of manufacture and use
USD732666S1 (en) 2005-05-13 2015-06-23 Medtronic Corevalve, Inc. Heart valve prosthesis
USD812226S1 (en) 2005-05-13 2018-03-06 Medtronic Corevalve Llc Heart valve prosthesis
US9504564B2 (en) 2005-05-13 2016-11-29 Medtronic Corevalve Llc Heart valve prosthesis and methods of manufacture and use
US9554903B2 (en) 2005-05-24 2017-01-31 Edwards Lifesciences Corporation Rapid deployment prosthetic heart valve
US20080200978A1 (en) * 2005-05-26 2008-08-21 Texas Heart Institute Surgical System and Method For Attaching a Prosthetic Vessel to a Hollow Structure
US8211169B2 (en) 2005-05-27 2012-07-03 Medtronic, Inc. Gasket with collar for prosthetic heart valves and methods for using them
US20090082619A1 (en) * 2005-06-09 2009-03-26 De Marchena Eduardo Method of treating cardiomyopathy
US20090099410A1 (en) * 2005-06-09 2009-04-16 De Marchena Eduardo Papillary Muscle Attachment for Left Ventricular Reduction
US9028545B2 (en) 2005-06-13 2015-05-12 Edwards Lifesciences Corporation Method of delivering a prosthetic heart valve
US8506625B2 (en) 2005-07-13 2013-08-13 Edwards Lifesciences Corporation Contoured sewing ring for a prosthetic mitral heart valve
US9839515B2 (en) 2005-12-22 2017-12-12 Symetis, SA Stent-valves for valve replacement and associated methods and systems for surgery
US9216082B2 (en) 2005-12-22 2015-12-22 Symetis Sa Stent-valves for valve replacement and associated methods and systems for surgery
US9078781B2 (en) 2006-01-11 2015-07-14 Medtronic, Inc. Sterile cover for compressible stents used in percutaneous device delivery systems
US7967857B2 (en) 2006-01-27 2011-06-28 Medtronic, Inc. Gasket with spring collar for prosthetic heart valves and methods for making and using them
US7749266B2 (en) 2006-02-27 2010-07-06 Aortx, Inc. Methods and devices for delivery of prosthetic heart valves and other prosthetics
US8403981B2 (en) 2006-02-27 2013-03-26 CardiacMC, Inc. Methods and devices for delivery of prosthetic heart valves and other prosthetics
US8147541B2 (en) 2006-02-27 2012-04-03 Aortx, Inc. Methods and devices for delivery of prosthetic heart valves and other prosthetics
US8075615B2 (en) 2006-03-28 2011-12-13 Medtronic, Inc. Prosthetic cardiac valve formed from pericardium material and methods of making same
US9331328B2 (en) 2006-03-28 2016-05-03 Medtronic, Inc. Prosthetic cardiac valve from pericardium material and methods of making same
US10058421B2 (en) 2006-03-28 2018-08-28 Medtronic, Inc. Prosthetic cardiac valve formed from pericardium material and methods of making same
US20070239254A1 (en) * 2006-04-07 2007-10-11 Chris Chia System for percutaneous delivery and removal of a prosthetic valve
US8821569B2 (en) 2006-04-29 2014-09-02 Medtronic, Inc. Multiple component prosthetic heart valve assemblies and methods for delivering them
US8021161B2 (en) 2006-05-01 2011-09-20 Edwards Lifesciences Corporation Simulated heart valve root for training and testing
US8585594B2 (en) 2006-05-24 2013-11-19 Phoenix Biomedical, Inc. Methods of assessing inner surfaces of body lumens or organs
US8057396B2 (en) 2006-05-24 2011-11-15 Phoenix Biomedical, Inc. Device for assessing a cardiac valve
US8376865B2 (en) 2006-06-20 2013-02-19 Cardiacmd, Inc. Torque shaft and torque shaft drive
US8500799B2 (en) 2006-06-20 2013-08-06 Cardiacmd, Inc. Prosthetic heart valves, support structures and systems and methods for implanting same
US8142492B2 (en) 2006-06-21 2012-03-27 Aortx, Inc. Prosthetic valve implantation systems
US8834564B2 (en) 2006-09-19 2014-09-16 Medtronic, Inc. Sinus-engaging valve fixation member
US9138312B2 (en) 2006-09-19 2015-09-22 Medtronic Ventor Technologies Ltd. Valve prostheses
US9642704B2 (en) 2006-09-19 2017-05-09 Medtronic Ventor Technologies Ltd. Catheter for implanting a valve prosthesis
US8771346B2 (en) 2006-09-19 2014-07-08 Medtronic Ventor Technologies Ltd. Valve prosthetic fixation techniques using sandwiching
US8876894B2 (en) 2006-09-19 2014-11-04 Medtronic Ventor Technologies Ltd. Leaflet-sensitive valve fixation member
US8876895B2 (en) 2006-09-19 2014-11-04 Medtronic Ventor Technologies Ltd. Valve fixation member having engagement arms
US9387071B2 (en) 2006-09-19 2016-07-12 Medtronic, Inc. Sinus-engaging valve fixation member
US8348996B2 (en) 2006-09-19 2013-01-08 Medtronic Ventor Technologies Ltd. Valve prosthesis implantation techniques
US8348995B2 (en) 2006-09-19 2013-01-08 Medtronic Ventor Technologies, Ltd. Axial-force fixation member for valve
US9913714B2 (en) 2006-09-19 2018-03-13 Medtronic, Inc. Sinus-engaging valve fixation member
US8414643B2 (en) 2006-09-19 2013-04-09 Medtronic Ventor Technologies Ltd. Sinus-engaging valve fixation member
US10004601B2 (en) 2006-09-19 2018-06-26 Medtronic Ventor Technologies Ltd. Valve prosthesis fixation techniques using sandwiching
US8747460B2 (en) 2006-09-19 2014-06-10 Medtronic Ventor Technologies Ltd. Methods for implanting a valve prothesis
US8771345B2 (en) 2006-09-19 2014-07-08 Medtronic Ventor Technologies Ltd. Valve prosthesis fixation techniques using sandwiching
US8052750B2 (en) 2006-09-19 2011-11-08 Medtronic Ventor Technologies Ltd Valve prosthesis fixation techniques using sandwiching
US9295550B2 (en) 2006-12-06 2016-03-29 Medtronic CV Luxembourg S.a.r.l. Methods for delivering a self-expanding valve
US8747459B2 (en) 2006-12-06 2014-06-10 Medtronic Corevalve Llc System and method for transapical delivery of an annulus anchored self-expanding valve
US20080147179A1 (en) * 2006-12-19 2008-06-19 St. Jude Medical, Inc. Prosthetic heart valve including stent structure and tissue leaflets, and related methods
US8353954B2 (en) * 2006-12-19 2013-01-15 St. Jude Medical, Inc. Prosthetic heart valve including stent structure and tissue leaflets, and related methods
US9510944B2 (en) 2006-12-19 2016-12-06 St. Jude Medical, Inc. Prosthetic heart valve including stent structure and tissue leaflets, and related methods
US9192470B2 (en) 2006-12-19 2015-11-24 St. Jude Medical, Inc. Prosthetic heart valve including stent structure and tissue leaflets, and related methods
US10010413B2 (en) 2006-12-19 2018-07-03 St. Jude Medical, Llc Prosthetic heart valve including stent structure and tissue leaflets, and related methods
US20080154355A1 (en) * 2006-12-22 2008-06-26 Netanel Benichou Implantable prosthetic valve assembly and method of making the same
US8236045B2 (en) 2006-12-22 2012-08-07 Edwards Lifesciences Corporation Implantable prosthetic valve assembly and method of making the same
US9114008B2 (en) 2006-12-22 2015-08-25 Edwards Lifesciences Corporation Implantable prosthetic valve assembly and method for making the same
US9504568B2 (en) 2007-02-16 2016-11-29 Medtronic, Inc. Replacement prosthetic heart valves and methods of implantation
US9585754B2 (en) 2007-04-20 2017-03-07 Medtronic, Inc. Implant for treatment of a heart valve, in particular a mitral valve, material including such an implant, and material for insertion thereof
US9237886B2 (en) 2007-04-20 2016-01-19 Medtronic, Inc. Implant for treatment of a heart valve, in particular a mitral valve, material including such an implant, and material for insertion thereof
US8747458B2 (en) 2007-08-20 2014-06-10 Medtronic Ventor Technologies Ltd. Stent loading tool and method for use thereof
US9393112B2 (en) 2007-08-20 2016-07-19 Medtronic Ventor Technologies Ltd. Stent loading tool and method for use thereof
US20140039614A1 (en) * 2007-08-21 2014-02-06 Symetis Sa Stent-Valves For Valve Replacement and Associated Methods and Systems for Surgery
US9078749B2 (en) 2007-09-13 2015-07-14 Georg Lutter Truncated cone heart valve stent
US9254192B2 (en) 2007-09-13 2016-02-09 Georg Lutter Truncated cone heart valve stent
US9730792B2 (en) 2007-09-13 2017-08-15 Georg Lutter Truncated cone heart valve stent
US9095433B2 (en) 2007-09-13 2015-08-04 Georg Lutter Truncated cone heart valve stent
US20090076599A1 (en) * 2007-09-17 2009-03-19 Medtronics, Inc. Heart valve holder assembly for use in valve implantation procedures
US8273118B2 (en) 2007-09-17 2012-09-25 Medtronic, Inc. Heart valve holder assembly for use in valve implantation procedures
US9636221B2 (en) 2007-09-26 2017-05-02 St. Jude Medical, Inc. Collapsible prosthetic heart valves
US9693859B2 (en) 2007-09-26 2017-07-04 St. Jude Medical, Llc Collapsible prosthetic heart valves
US9820851B2 (en) 2007-09-28 2017-11-21 St. Jude Medical, Llc Collapsible-expandable prosthetic heart valves with structures for clamping native tissue
US9848981B2 (en) 2007-10-12 2017-12-26 Mayo Foundation For Medical Education And Research Expandable valve prosthesis with sealing mechanism
US9839513B2 (en) 2007-10-25 2017-12-12 Symetis Sa Stents, valved-stents and methods and systems for delivery thereof
US7846199B2 (en) 2007-11-19 2010-12-07 Cook Incorporated Remodelable prosthetic valve
US20090157175A1 (en) * 2007-12-14 2009-06-18 Edwards Lifesciences Corporation Leaflet attachment frame for a prosthetic valve
US9510942B2 (en) * 2007-12-14 2016-12-06 Edwards Lifesciences Corporation Leaflet attachment frame for a prosthetic valve
US8157852B2 (en) 2008-01-24 2012-04-17 Medtronic, Inc. Delivery systems and methods of implantation for prosthetic heart valves
US8157853B2 (en) 2008-01-24 2012-04-17 Medtronic, Inc. Delivery systems and methods of implantation for prosthetic heart valves
US8673000B2 (en) 2008-01-24 2014-03-18 Medtronic, Inc. Stents for prosthetic heart valves
US8685077B2 (en) 2008-01-24 2014-04-01 Medtronics, Inc. Delivery systems and methods of implantation for prosthetic heart valves
US9089422B2 (en) 2008-01-24 2015-07-28 Medtronic, Inc. Markers for prosthetic heart valves
US8628566B2 (en) 2008-01-24 2014-01-14 Medtronic, Inc. Stents for prosthetic heart valves
US9393115B2 (en) 2008-01-24 2016-07-19 Medtronic, Inc. Delivery systems and methods of implantation for prosthetic heart valves
US9925079B2 (en) 2008-01-24 2018-03-27 Medtronic, Inc. Delivery systems and methods of implantation for prosthetic heart valves
US9333100B2 (en) 2008-01-24 2016-05-10 Medtronic, Inc. Stents for prosthetic heart valves
US9149358B2 (en) 2008-01-24 2015-10-06 Medtronic, Inc. Delivery systems for prosthetic heart valves
US7972378B2 (en) 2008-01-24 2011-07-05 Medtronic, Inc. Stents for prosthetic heart valves
US9339382B2 (en) 2008-01-24 2016-05-17 Medtronic, Inc. Stents for prosthetic heart valves
US10016274B2 (en) 2008-01-24 2018-07-10 Medtronic, Inc. Stent for prosthetic heart valves
US8961593B2 (en) 2008-02-28 2015-02-24 Medtronic, Inc. Prosthetic heart valve systems
US8613765B2 (en) 2008-02-28 2013-12-24 Medtronic, Inc. Prosthetic heart valve systems
US20090228093A1 (en) * 2008-02-29 2009-09-10 Edwards Lifesciences Corporation Expandable member for deploying a prosthetic device
US8784480B2 (en) 2008-02-29 2014-07-22 Edwards Lifesciences Corporation Expandable member for deploying a prosthetic device
US10076412B2 (en) 2008-02-29 2018-09-18 Edwards Lifesciences Corporation Expandable member for deploying a prosthetic device
US9241792B2 (en) 2008-02-29 2016-01-26 Edwards Lifesciences Corporation Two-step heart valve implantation
US8460368B2 (en) 2008-02-29 2013-06-11 Edwards Lifesciences Corporation Expandable member for deploying a prosthetic device
US9592120B2 (en) 2008-03-18 2017-03-14 Medtronic Ventor Technologies, Ltd. Valve suturing and implantation procedures
US8313525B2 (en) 2008-03-18 2012-11-20 Medtronic Ventor Technologies, Ltd. Valve suturing and implantation procedures
US8430927B2 (en) 2008-04-08 2013-04-30 Medtronic, Inc. Multiple orifice implantable heart valve and methods of implantation
US8696743B2 (en) 2008-04-23 2014-04-15 Medtronic, Inc. Tissue attachment devices and methods for prosthetic heart valves
US8511244B2 (en) 2008-04-23 2013-08-20 Medtronic, Inc. Methods and apparatuses for assembly of a pericardial prosthetic heart valve
US8312825B2 (en) 2008-04-23 2012-11-20 Medtronic, Inc. Methods and apparatuses for assembly of a pericardial prosthetic heart valve
US20090276040A1 (en) * 2008-05-01 2009-11-05 Edwards Lifesciences Corporation Device and method for replacing mitral valve
US20090281619A1 (en) * 2008-05-09 2009-11-12 Edwards Lifesciences Corporation Low Profile Delivery System for Transcatheter Heart Valve
US9061119B2 (en) 2008-05-09 2015-06-23 Edwards Lifesciences Corporation Low profile delivery system for transcatheter heart valve
US8840661B2 (en) 2008-05-16 2014-09-23 Sorin Group Italia S.R.L. Atraumatic prosthetic heart valve prosthesis
US20090287296A1 (en) * 2008-05-16 2009-11-19 Sorin Biomedica Cardio S.R.L. Atraumatic prosthetic heart valve prosthesis
US9662204B2 (en) 2008-06-06 2017-05-30 Edwards Lifesciences Corporation Low profile transcatheter heart valve
US7993394B2 (en) 2008-06-06 2011-08-09 Ilia Hariton Low profile transcatheter heart valve
US8454685B2 (en) 2008-06-06 2013-06-04 Edwards Lifesciences Corporation Low profile transcatheter heart valve
US8236049B2 (en) 2008-06-20 2012-08-07 Edwards Lifesciences Corporation Multipiece prosthetic mitral valve and method
US9561101B2 (en) 2008-06-20 2017-02-07 Edwards Lifesciences Corporation Two-part prosthetic valve system
US20090319037A1 (en) * 2008-06-20 2009-12-24 Edwards Lifesciences Corporation Retaining mechanisms for prosthetic valves
US9993338B2 (en) 2008-06-20 2018-06-12 Edwards Lifesciences Corporation Methods for retaining a prosthetic heart valve
US8323335B2 (en) 2008-06-20 2012-12-04 Edwards Lifesciences Corporation Retaining mechanisms for prosthetic valves and methods for using
US9681949B2 (en) 2008-07-15 2017-06-20 St. Jude Medical, Llc Collapsible and re-expandable prosthetic heart valve cuff designs and complementary technological applications
US9675449B2 (en) 2008-07-15 2017-06-13 St. Jude Medical, Llc Collapsible and re-expandable prosthetic heart valve cuff designs and complementary technological applications
US10010410B2 (en) 2008-07-15 2018-07-03 St. Jude Medical, Llc Collapsible and re-expandable prosthetic heart valve cuff designs and complementary technological applications
US9364325B2 (en) 2008-08-22 2016-06-14 Edwards Lifesciences Corporation Prosthetic heart valve delivery system and method
US8652202B2 (en) 2008-08-22 2014-02-18 Edwards Lifesciences Corporation Prosthetic heart valve and delivery apparatus
US20100049313A1 (en) * 2008-08-22 2010-02-25 Edwards Lifesciences Corporation Prosthetic heart valve and delivery apparatus
US8998981B2 (en) 2008-09-15 2015-04-07 Medtronic, Inc. Prosthetic heart valve having identifiers for aiding in radiographic positioning
US9943407B2 (en) 2008-09-15 2018-04-17 Medtronic, Inc. Prosthetic heart valve having identifiers for aiding in radiographic positioning
US8721714B2 (en) 2008-09-17 2014-05-13 Medtronic Corevalve Llc Delivery system for deployment of medical devices
US9532873B2 (en) 2008-09-17 2017-01-03 Medtronic CV Luxembourg S.a.r.l. Methods for deployment of medical devices
US9301840B2 (en) 2008-10-10 2016-04-05 Edwards Lifesciences Corporation Expandable introducer sheath
US8137398B2 (en) 2008-10-13 2012-03-20 Medtronic Ventor Technologies Ltd Prosthetic valve having tapered tip when compressed for delivery
US8986361B2 (en) 2008-10-17 2015-03-24 Medtronic Corevalve, Inc. Delivery system for deployment of medical devices
US20100174359A1 (en) * 2008-10-29 2010-07-08 Symetis Sa Methods and Systems for Stent-Valve Manufacture and Assembly
US9314334B2 (en) 2008-11-25 2016-04-19 Edwards Lifesciences Corporation Conformal expansion of prosthetic devices to anatomical shapes
US20100161036A1 (en) * 2008-12-19 2010-06-24 Edwards Lifesciences Corporation Quick-connect prosthetic heart valve and methods
US9561100B2 (en) 2008-12-19 2017-02-07 Edwards Lifesciences Corporation Systems for quickly delivering a prosthetic heart valve
US8308798B2 (en) 2008-12-19 2012-11-13 Edwards Lifesciences Corporation Quick-connect prosthetic heart valve and methods
US9005278B2 (en) 2008-12-19 2015-04-14 Edwards Lifesciences Corporation Quick-connect prosthetic heart valve
US10098733B2 (en) 2008-12-23 2018-10-16 Sorin Group Italia S.R.L. Expandable prosthetic valve having anchoring appendages
US8834563B2 (en) 2008-12-23 2014-09-16 Sorin Group Italia S.R.L. Expandable prosthetic valve having anchoring appendages
US20100185278A1 (en) * 2009-01-21 2010-07-22 Tendyne Medical Apical Papillary Msucle Attachment for Left Ventricular Reduction
US20110112632A1 (en) * 2009-02-25 2011-05-12 Edwards Lifesciences Corporation Method of implanting a prosthetic valve in a mitral valve with pulmonary vein anchoring
US20100217382A1 (en) * 2009-02-25 2010-08-26 Edwards Lifesciences Mitral valve replacement with atrial anchoring
US8252051B2 (en) 2009-02-25 2012-08-28 Edwards Lifesciences Corporation Method of implanting a prosthetic valve in a mitral valve with pulmonary vein anchoring
US9248016B2 (en) 2009-03-31 2016-02-02 Edwards Lifesciences Corporation Prosthetic heart valve system
US9980818B2 (en) 2009-03-31 2018-05-29 Edwards Lifesciences Corporation Prosthetic heart valve system with positioning markers
US9931207B2 (en) 2009-03-31 2018-04-03 Edwards Lifesciences Corporation Methods of implanting a heart valve at an aortic annulus
US20100274351A1 (en) * 2009-04-27 2010-10-28 Sorin Biomedica Cardio S.R.I. Prosthetic vascular conduit
US8512397B2 (en) 2009-04-27 2013-08-20 Sorin Group Italia S.R.L. Prosthetic vascular conduit
US20100331972A1 (en) * 2009-06-26 2010-12-30 Edwards Lifesciences Corporation Unitary Quick Connect Prosthetic Heart Valve and Deployment System and Methods
US8348998B2 (en) 2009-06-26 2013-01-08 Edwards Lifesciences Corporation Unitary quick connect prosthetic heart valve and deployment system and methods
US8696742B2 (en) 2009-06-26 2014-04-15 Edwards Lifesciences Corporation Unitary quick-connect prosthetic heart valve deployment methods
US9005277B2 (en) 2009-06-26 2015-04-14 Edwards Lifesciences Corporation Unitary quick-connect prosthetic heart valve deployment system
US9717594B2 (en) 2009-07-14 2017-08-01 Edwards Lifesciences Corporation Methods of valve delivery on a beating heart
US8808369B2 (en) 2009-10-05 2014-08-19 Mayo Foundation For Medical Education And Research Minimally invasive aortic valve replacement
US9603553B2 (en) 2009-10-27 2017-03-28 Edwards Lifesciences Corporation Methods of measuring heart valve annuluses for valve replacement
US8449625B2 (en) 2009-10-27 2013-05-28 Edwards Lifesciences Corporation Methods of measuring heart valve annuluses for valve replacement
US9084676B2 (en) 2009-12-04 2015-07-21 Edwards Lifesciences Corporation Apparatus for treating a mitral valve
US9433500B2 (en) 2009-12-04 2016-09-06 Edwards Lifesciences Corporation Prosthetic valve for replacing mitral valve
US8986373B2 (en) 2009-12-04 2015-03-24 Edwards Lifesciences Corporation Method for implanting a prosthetic mitral valve
US8449599B2 (en) 2009-12-04 2013-05-28 Edwards Lifesciences Corporation Prosthetic valve for replacing mitral valve
US9717591B2 (en) 2009-12-04 2017-08-01 Edwards Lifesciences Corporation Prosthetic valve for replacing mitral valve
US8926691B2 (en) 2009-12-04 2015-01-06 Edwards Lifesciences Corporation Apparatus for treating a mitral valve
US9226826B2 (en) 2010-02-24 2016-01-05 Medtronic, Inc. Transcatheter valve structure and methods for valve delivery
US8795354B2 (en) 2010-03-05 2014-08-05 Edwards Lifesciences Corporation Low-profile heart valve and delivery system
US9925044B2 (en) 2010-04-01 2018-03-27 Medtronic, Inc. Transcatheter valve with torsion spring fixation and related systems and methods
US8652204B2 (en) 2010-04-01 2014-02-18 Medtronic, Inc. Transcatheter valve with torsion spring fixation and related systems and methods
US20110257721A1 (en) * 2010-04-15 2011-10-20 Medtronic, Inc. Prosthetic Heart Valves and Delivery Methods
US8986374B2 (en) 2010-05-10 2015-03-24 Edwards Lifesciences Corporation Prosthetic heart valve
US9554901B2 (en) 2010-05-12 2017-01-31 Edwards Lifesciences Corporation Low gradient prosthetic heart valve
US9248017B2 (en) 2010-05-21 2016-02-02 Sorin Group Italia S.R.L. Support device for valve prostheses and corresponding kit
US9931206B2 (en) 2010-07-09 2018-04-03 Highlife Sas Transcatheter atrio-ventricular valve prosthesis
US9375312B2 (en) 2010-07-09 2016-06-28 Highlife Sas Transcatheter atrio-ventricular valve prosthesis
US9326853B2 (en) 2010-07-23 2016-05-03 Edwards Lifesciences Corporation Retaining mechanisms for prosthetic valves
US9918833B2 (en) 2010-09-01 2018-03-20 Medtronic Vascular Galway Prosthetic valve support structure
US9370418B2 (en) 2010-09-10 2016-06-21 Edwards Lifesciences Corporation Rapidly deployable surgical heart valves
US9504563B2 (en) 2010-09-10 2016-11-29 Edwards Lifesciences Corporation Rapidly deployable surgical heart valves
US9968450B2 (en) 2010-09-10 2018-05-15 Edwards Lifesciences Corporation Methods for ensuring safe and rapid deployment of prosthetic heart valves
US9125741B2 (en) 2010-09-10 2015-09-08 Edwards Lifesciences Corporation Systems and methods for ensuring safe and rapid deployment of prosthetic heart valves
US8641757B2 (en) 2010-09-10 2014-02-04 Edwards Lifesciences Corporation Systems for rapidly deploying surgical heart valves
US10039641B2 (en) 2010-09-10 2018-08-07 Edwards Lifesciences Corporation Methods of rapidly deployable surgical heart valves
US9861479B2 (en) 2010-09-27 2018-01-09 Edwards Lifesciences Corporation Methods of delivery of flexible heart valves
US8845720B2 (en) 2010-09-27 2014-09-30 Edwards Lifesciences Corporation Prosthetic heart valve frame with flexible commissures
US8568475B2 (en) 2010-10-05 2013-10-29 Edwards Lifesciences Corporation Spiraled commissure attachment for prosthetic valve
US9393110B2 (en) 2010-10-05 2016-07-19 Edwards Lifesciences Corporation Prosthetic heart valve
US9161836B2 (en) 2011-02-14 2015-10-20 Sorin Group Italia S.R.L. Sutureless anchoring device for cardiac valve prostheses
US9289289B2 (en) 2011-02-14 2016-03-22 Sorin Group Italia S.R.L. Sutureless anchoring device for cardiac valve prostheses
US20140005773A1 (en) * 2011-02-18 2014-01-02 David J. Wheatley Heart Valve
US9259313B2 (en) * 2011-02-18 2016-02-16 David J. Wheatley Heart valve
US9155619B2 (en) 2011-02-25 2015-10-13 Edwards Lifesciences Corporation Prosthetic heart valve delivery apparatus
US9999506B2 (en) 2011-05-31 2018-06-19 Edwards Lifesciences Corporation System and method for treating valve insufficiency or vessel dilatation
US9289282B2 (en) 2011-05-31 2016-03-22 Edwards Lifesciences Corporation System and method for treating valve insufficiency or vessel dilatation
US8998976B2 (en) 2011-07-12 2015-04-07 Boston Scientific Scimed, Inc. Coupling system for medical devices
US20130018458A1 (en) * 2011-07-15 2013-01-17 Edwards Lifesciences Corporation Perivalvular sealing for transcatheter heart valve
US10076411B2 (en) 2011-07-15 2018-09-18 Edwards Lifesciences Corporation Perivalvular sealing for transcatheter heart valve
US8795357B2 (en) * 2011-07-15 2014-08-05 Edwards Lifesciences Corporation Perivalvular sealing for transcatheter heart valve
US10028826B2 (en) 2011-07-15 2018-07-24 Edwards Lifesciences Corporation Perivalvular sealing for transcatheter heart valve
US9119716B2 (en) 2011-07-27 2015-09-01 Edwards Lifesciences Corporation Delivery systems for prosthetic heart valve
US9339384B2 (en) 2011-07-27 2016-05-17 Edwards Lifesciences Corporation Delivery systems for prosthetic heart valve
US9480559B2 (en) 2011-08-11 2016-11-01 Tendyne Holdings, Inc. Prosthetic valves and related inventions
US9833315B2 (en) 2011-08-11 2017-12-05 Tendyne Holdings, Inc. Prosthetic valves and related inventions
US9474598B2 (en) 2011-10-05 2016-10-25 Boston Scientific Scimed, Inc. Profile reduction seal
US9510947B2 (en) 2011-10-21 2016-12-06 Jenavalve Technology, Inc. Catheter system for introducing an expandable heart valve stent into the body of a patient
US9370421B2 (en) 2011-12-03 2016-06-21 Boston Scientific Scimed, Inc. Medical device handle
US9168131B2 (en) 2011-12-09 2015-10-27 Edwards Lifesciences Corporation Prosthetic heart valve having improved commissure supports
US9757229B2 (en) 2011-12-09 2017-09-12 Edwards Lifesciences Corporation Prosthetic heart valve having improved commissure supports
US9827092B2 (en) 2011-12-16 2017-11-28 Tendyne Holdings, Inc. Tethers for prosthetic mitral valve
US9078747B2 (en) 2011-12-21 2015-07-14 Edwards Lifesciences Corporation Anchoring device for replacing or repairing a heart valve
US9138314B2 (en) 2011-12-29 2015-09-22 Sorin Group Italia S.R.L. Prosthetic vascular conduit and assembly method
US8685084B2 (en) 2011-12-29 2014-04-01 Sorin Group Italia S.R.L. Prosthetic vascular conduit and assembly method
US9878127B2 (en) 2012-05-16 2018-01-30 Jenavalve Technology, Inc. Catheter delivery system for heart valve prosthesis
US9895221B2 (en) 2012-07-28 2018-02-20 Tendyne Holdings, Inc. Multi-component designs for heart valve retrieval device, sealing structures and stent assembly
US9675454B2 (en) 2012-07-30 2017-06-13 Tendyne Holdings, Inc. Delivery systems and methods for transcatheter prosthetic valves
US9907652B2 (en) 2012-09-06 2018-03-06 Edwards Lifesciences Corporation Heart valve sealing devices
US9414918B2 (en) 2012-09-06 2016-08-16 Edwards Lifesciences Corporation Heart valve sealing devices
US9510946B2 (en) 2012-09-06 2016-12-06 Edwards Lifesciences Corporation Heart valve sealing devices
US10016276B2 (en) 2012-11-21 2018-07-10 Edwards Lifesciences Corporation Retaining mechanisms for prosthetic heart valves
WO2014120507A1 (en) * 2013-01-29 2014-08-07 St. Jude Medical, Cardiology Division, Inc. Surgical heart valve flexible stent frame stiffener
US9655719B2 (en) 2013-01-29 2017-05-23 St. Jude Medical, Cardiology Division, Inc. Surgical heart valve flexible stent frame stiffener
JP2016504154A (en) * 2013-01-29 2016-02-12 セント・ジュード・メディカル,カーディオロジー・ディヴィジョン,インコーポレイテッド Flexible stent frame of the surgical heart valve stiffener
US9439763B2 (en) 2013-02-04 2016-09-13 Edwards Lifesciences Corporation Prosthetic valve for replacing mitral valve
US9675452B2 (en) 2013-02-12 2017-06-13 Edwards Lifesciences Corporation Artificial heart valve with scalloped frame design
US9168129B2 (en) 2013-02-12 2015-10-27 Edwards Lifesciences Corporation Artificial heart valve with scalloped frame design
US10058425B2 (en) 2013-03-15 2018-08-28 Edwards Lifesciences Corporation Methods of assembling a valved aortic conduit
US9486306B2 (en) 2013-04-02 2016-11-08 Tendyne Holdings, Inc. Inflatable annular sealing device for prosthetic mitral valve
US9629718B2 (en) 2013-05-03 2017-04-25 Medtronic, Inc. Valve delivery tool
US9867700B2 (en) 2013-05-20 2018-01-16 Edwards Lifesciences Corporation Prosthetic heart valve delivery apparatus
US9610159B2 (en) 2013-05-30 2017-04-04 Tendyne Holdings, Inc. Structural members for prosthetic mitral valves
US9968451B2 (en) 2013-06-12 2018-05-15 Edwards Lifesciences Corporation Cardiac implant with integrated suture fasteners
US9468527B2 (en) 2013-06-12 2016-10-18 Edwards Lifesciences Corporation Cardiac implant with integrated suture fasteners
US9597181B2 (en) 2013-06-25 2017-03-21 Tendyne Holdings, Inc. Thrombus management and structural compliance features for prosthetic heart valves
US10052198B2 (en) 2013-08-14 2018-08-21 Mitral Valve Technologies Sarl Coiled anchor for supporting prosthetic heart valve, prosthetic heart valve, and deployment device
US9919137B2 (en) 2013-08-28 2018-03-20 Edwards Lifesciences Corporation Integrated balloon catheter inflation system
US9867694B2 (en) 2013-08-30 2018-01-16 Jenavalve Technology Inc. Radially collapsible frame for a prosthetic valve and method for manufacturing such a frame
US9526611B2 (en) 2013-10-29 2016-12-27 Tendyne Holdings, Inc. Apparatus and methods for delivery of transcatheter prosthetic valves
US9913715B2 (en) 2013-11-06 2018-03-13 St. Jude Medical, Cardiology Division, Inc. Paravalvular leak sealing mechanism
US9622863B2 (en) 2013-11-22 2017-04-18 Edwards Lifesciences Corporation Aortic insufficiency repair device and method
US10098734B2 (en) 2013-12-05 2018-10-16 Edwards Lifesciences Corporation Prosthetic heart valve and delivery apparatus
US9901444B2 (en) 2013-12-17 2018-02-27 Edwards Lifesciences Corporation Inverted valve structure
US9986993B2 (en) 2014-02-11 2018-06-05 Tendyne Holdings, Inc. Adjustable tether and epicardial pad system for prosthetic heart valve
US10058420B2 (en) 2014-02-18 2018-08-28 Edwards Lifesciences Corporation Flexible commissure frame
US10052199B2 (en) 2014-02-21 2018-08-21 Mitral Valve Technologies Sarl Devices, systems and methods for delivering a prosthetic mitral valve and anchoring device
US9549816B2 (en) 2014-04-03 2017-01-24 Edwards Lifesciences Corporation Method for manufacturing high durability heart valve
US9585752B2 (en) 2014-04-30 2017-03-07 Edwards Lifesciences Corporation Holder and deployment system for surgical heart valves
US9532870B2 (en) 2014-06-06 2017-01-03 Edwards Lifesciences Corporation Prosthetic valve for replacing a mitral valve
US9504566B2 (en) 2014-06-20 2016-11-29 Edwards Lifesciences Corporation Surgical heart valves identifiable post-implant
US10058424B2 (en) 2014-08-21 2018-08-28 Edwards Lifesciences Corporation Dual-flange prosthetic valve frame
US9901445B2 (en) 2014-11-21 2018-02-27 Boston Scientific Scimed, Inc. Valve locking mechanism
US9861477B2 (en) 2015-01-26 2018-01-09 Boston Scientific Scimed Inc. Prosthetic heart valve square leaflet-leaflet stitch
US9788942B2 (en) 2015-02-03 2017-10-17 Boston Scientific Scimed Inc. Prosthetic heart valve having tubular seal
US10039637B2 (en) 2015-02-11 2018-08-07 Edwards Lifesciences Corporation Heart valve docking devices and implanting methods
US10080652B2 (en) 2015-03-13 2018-09-25 Boston Scientific Scimed, Inc. Prosthetic heart valve having an improved tubular seal
US10064718B2 (en) 2015-04-16 2018-09-04 Edwards Lifesciences Corporation Low-profile prosthetic heart valve for replacing a mitral valve
US10010417B2 (en) 2015-04-16 2018-07-03 Edwards Lifesciences Corporation Low-profile prosthetic heart valve for replacing a mitral valve
US9974650B2 (en) 2015-07-14 2018-05-22 Edwards Lifesciences Corporation Prosthetic heart valve
US10080653B2 (en) 2015-09-10 2018-09-25 Edwards Lifesciences Corporation Limited expansion heart valve

Similar Documents

Publication Publication Date Title
US7381220B2 (en) Devices, systems, and methods for supplementing, repairing, or replacing a native heart valve leaflet
US4290151A (en) Adjustable annular prosthesis for cardiac surgery
US8801776B2 (en) Infundibular reducer devices
US5397351A (en) Prosthetic valve for percutaneous insertion
US5163953A (en) Toroidal artificial heart valve stent
US8075611B2 (en) Stented prosthetic heart valves
US7399315B2 (en) Minimally-invasive heart valve with cusp positioners
US3983581A (en) Heart valve stent
EP0125393B1 (en) Prosthetic heart valve
US3656185A (en) Cardiac valvular support prosthesis
US5489297A (en) Bioprosthetic heart valve with absorbable stent
US6602289B1 (en) Annuloplasty rings of particular use in surgery for the mitral valve
US6610088B1 (en) Biologically covered heart valve prosthesis
US7247167B2 (en) Low profile heart valve prosthesis
US6767362B2 (en) Minimally-invasive heart valves and methods of use
US20110295363A1 (en) Prosthetic Heart Valve And Transcatheter Delivered Endoprosthesis Comprising A Prosthetic Heart Valve And A Stent
US20040148018A1 (en) Flexible heart valve and associated connecting band
US6478819B2 (en) Prosthetic heart valves with flexible post geometry
US7473275B2 (en) Stress absorbing flexible heart valve frame
US20100274351A1 (en) Prosthetic vascular conduit
US20080103586A1 (en) Implant for placing in a blood circulation conduit
US20050165478A1 (en) Apparatus for restoring aortic valve and treatment method using thereof
US7524331B2 (en) Catheter delivered valve having a barrier to provide an enhanced seal
US4917698A (en) Multi-segmented annuloplasty ring prosthesis
US4339831A (en) Dynamic annulus heart valve and reconstruction ring

Legal Events

Date Code Title Description
AS Assignment

Owner name: EXTRACORPOREAL MEDICAL SPECIALTIES, INC. A PA. COR

Free format text: MERGER;ASSIGNOR:VASCOR INC., A CORP OF CA (INTO);REEL/FRAME:004202/0030

Effective date: 19820104

Owner name: VASCOR INC.

Free format text: CHANGE OF NAME;ASSIGNOR:HANCOCK LABORATORIES INCORPORATED;REEL/FRAME:004202/0026

Effective date: 19800901

AS Assignment

Owner name: MEDTRONIC, INC., 7000 CENTRAL AVENUE, N.E., MINNEA

Free format text: ASSIGNMENT OF ASSIGNORS INTEREST.;ASSIGNOR:MCNEILAB, INC.;REEL/FRAME:004809/0919

Effective date: 19871207