JP2018535203A5 - - Google Patents
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- JP2018535203A5 JP2018535203A5 JP2018520089A JP2018520089A JP2018535203A5 JP 2018535203 A5 JP2018535203 A5 JP 2018535203A5 JP 2018520089 A JP2018520089 A JP 2018520089A JP 2018520089 A JP2018520089 A JP 2018520089A JP 2018535203 A5 JP2018535203 A5 JP 2018535203A5
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- 0 CC(C)(*C(C)(*)N(*)C(C1*=*(*N(*)*c2nc(C=CC(C)(*)C=C3)c3[n]2)*=*1)=O)C1=NC=CC(C)(*)C=C1 Chemical compound CC(C)(*C(C)(*)N(*)C(C1*=*(*N(*)*c2nc(C=CC(C)(*)C=C3)c3[n]2)*=*1)=O)C1=NC=CC(C)(*)C=C1 0.000 description 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2020091830A JP6967112B2 (ja) | 2015-10-23 | 2020-05-27 | 新規なフェロポーチン阻害剤 |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP15191179.9 | 2015-10-23 | ||
| EP15191176 | 2015-10-23 | ||
| EP15191179 | 2015-10-23 | ||
| EP15191176.5 | 2015-10-23 | ||
| PCT/EP2016/075306 WO2017068090A1 (en) | 2015-10-23 | 2016-10-21 | Novel ferroportin inhibitors |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020091830A Division JP6967112B2 (ja) | 2015-10-23 | 2020-05-27 | 新規なフェロポーチン阻害剤 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018535203A JP2018535203A (ja) | 2018-11-29 |
| JP2018535203A5 true JP2018535203A5 (enExample) | 2019-03-14 |
| JP6710754B2 JP6710754B2 (ja) | 2020-06-17 |
Family
ID=57178421
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018520089A Active JP6710754B2 (ja) | 2015-10-23 | 2016-10-21 | 新規なフェロポーチン阻害剤 |
| JP2018520090A Active JP6810988B2 (ja) | 2015-10-23 | 2016-10-21 | 新規なフェロポーチン阻害剤 |
| JP2020091830A Active JP6967112B2 (ja) | 2015-10-23 | 2020-05-27 | 新規なフェロポーチン阻害剤 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018520090A Active JP6810988B2 (ja) | 2015-10-23 | 2016-10-21 | 新規なフェロポーチン阻害剤 |
| JP2020091830A Active JP6967112B2 (ja) | 2015-10-23 | 2020-05-27 | 新規なフェロポーチン阻害剤 |
Country Status (32)
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RS62633B1 (sr) | 2013-03-15 | 2021-12-31 | Protagonist Therapeutics Inc | Analozi hepcidina i njihove primene |
| AU2016342310B2 (en) * | 2015-10-23 | 2020-08-27 | Vifor (International) Ag | Novel ferroportin inhibitors |
| JOP20180036A1 (ar) | 2017-04-18 | 2019-01-30 | Vifor Int Ag | أملاح لمثبطات فروبورتين جديدة |
| CN108314687A (zh) * | 2017-12-27 | 2018-07-24 | 重庆文理学院 | 1,2-二氢苯并[4,5]咪唑并[1,2-a]吡嗪-3（4H）-酮衍生物的合成 |
| EP4501952A3 (en) | 2018-02-08 | 2025-04-16 | Protagonist Therapeutics, Inc. | Conjugated hepcidin mimetics |
| EP3788065B1 (en) | 2018-04-30 | 2025-08-27 | The Children's Hospital Of Philadelphia | Improving anemias by combining agents |
| ES2934492T3 (es) | 2018-12-13 | 2023-02-22 | Global Blood Therapeutics Inc | Inhibidores de ferroportina y métodos de uso |
| TW202102478A (zh) | 2019-04-01 | 2021-01-16 | 瑞士商威佛（國際）股份有限公司 | 新穎的鐵螯合物 |
| EP3999060A1 (en) | 2019-07-19 | 2022-05-25 | Vifor (International) Ag | Ferroportin-inhibitors for the use in the prevention and treatment of kidney injuries |
| MX2022000782A (es) * | 2019-07-19 | 2022-04-18 | Vifor Int Ag | Inhibidores de la ferroportina para el uso en el tratamiento de la beta-talasemia dependiente de transfusiones (tdt). |
| EP3782702A1 (en) * | 2019-08-21 | 2021-02-24 | AC BioScience SA | Compounds and use thereof for the treatment of infectious diseases and cancer |
| MX2022002633A (es) | 2019-09-03 | 2022-06-02 | Protagonist Therapeutics Inc | Mimeticos de hepcidina conjugada. |
| AU2020369137A1 (en) | 2019-10-22 | 2022-04-07 | Vifor (International) Ag | Methods and compositions for treating sickle cell disease with a ferroportin inhibitor (VIT-2763) |
| CN115362154A (zh) * | 2020-03-24 | 2022-11-18 | 威佛（国际）股份公司 | 膜铁转运蛋白抑制剂的制备方法 |
| WO2021222363A1 (en) * | 2020-04-28 | 2021-11-04 | Global Blood Therapeutics, Inc. | Cycloalkyl pyrimidines as ferroportin inhibitors |
| GB202012969D0 (en) * | 2020-08-19 | 2020-09-30 | Univ Of Oxford | Inhibitor compounds |
| KR20230134476A (ko) * | 2021-01-20 | 2023-09-21 | 비포르 (인터내셔날) 아게 | 골수이형성 증후군(mds)의 치료에 사용하기 위한 페로포틴-억제제 |
| WO2022173818A1 (en) * | 2021-02-09 | 2022-08-18 | University Of Virginia Patent Foundation | Use of biliverdin reductase b inhibitors to allow malaria eradication in patients with g6pd deficiency |
| JP2024512595A (ja) * | 2021-03-26 | 2024-03-19 | キエシ・フアルマチエウテイチ・ソチエタ・ペル・アチオニ | Ｄｄｒ阻害剤としてのテトラヒドロチエノピリジン誘導体 |
| TW202304896A (zh) * | 2021-04-22 | 2023-02-01 | 瑞士商威佛（國際）股份有限公司 | 經修飾的膜鐵運輸蛋白(ferroportin)抑制劑 |
| WO2023046664A1 (en) | 2021-09-21 | 2023-03-30 | Vifor (International) Ag | N-substituted ferroportin inhibitors |
| JP2025535398A (ja) | 2022-10-21 | 2025-10-24 | ビフォー （インターナショナル） エージー | 二環式フェロポーチン阻害剤 |
| CN115974864B (zh) * | 2022-12-29 | 2025-09-16 | 苏州汉德创宏生化科技有限公司 | 一种2-(3-氮杂环丁基)噻唑盐的合成方法 |
| EP4687983A1 (en) | 2023-03-27 | 2026-02-11 | Silence Therapeutics GmbH | Compounds and compositions for use in stem cell transplantation |
| AU2024310149A1 (en) | 2023-06-26 | 2025-11-20 | Vifor (International) Ag | Ferroportin-inhibitors for the use in the treatment of hereditary haemochromatosis (hh) |
| WO2026041650A1 (en) | 2024-08-20 | 2026-02-26 | Vifor (International) Ag | Ferroportin-inhibitors for the use in the treatment of lupus nephritis |
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| CH479616A (de) * | 1959-12-24 | 1969-10-15 | Ciba Geigy | Verfahren zur Herstellung neuer Methylidenverbindungen |
| GB937878A (en) | 1959-12-24 | 1963-09-25 | Ciba Ltd | N-[5-nitro-(2)-furfurylidene]-pyrazole-carboxylic acid hydrazides and process for their manufacture |
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| US5922761A (en) | 1996-09-06 | 1999-07-13 | Medinox, Inc. | Methods for in vivo reduction of iron levels and compositions useful therefor |
| AR009655A1 (es) | 1996-12-10 | 2000-04-26 | Novartis Ag | Una composicion parenteralmente inyectable, un metodo para su preparacion, metodos para el tratamiento de enfermedades, una modificacion decristal de 1-decansulfonato de desferrioxamina, su uso, un proceso para la produccion de dicha modificacion de cristal y una preparacion farmaceutica que |
| JP2001505585A (ja) | 1996-12-16 | 2001-04-24 | 藤沢薬品工業株式会社 | 新規アミド化合物およびそれらの一酸化窒素シンターゼ阻害剤としての用途 |
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| DE10356409B4 (de) | 2003-11-28 | 2006-12-28 | Biofrontera Discovery Gmbh | Neues Arzneimittel Oxachelin und Derivate |
| FR2870271B1 (fr) | 2004-05-11 | 2008-03-14 | Bruno Merand | Procede de construction d'une maison en bois et moyens pour la mise en oeuvre du procede. |
| WO2006004841A2 (en) * | 2004-06-29 | 2006-01-12 | The Scripps Research Institute | Galanin agonists |
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| JP6838966B2 (ja) * | 2013-11-22 | 2021-03-03 | ユニバーシティー オブ フロリダ リサーチ ファンデーション， インク． | デスフェリチオシン類似体およびその使用 |
| KR20170092634A (ko) * | 2014-12-05 | 2017-08-11 | 에이엔2에이치 디스커버리 리미티드 | 파킨 리가제 활성화 방법 및 조성물 |
| AU2016342310B2 (en) * | 2015-10-23 | 2020-08-27 | Vifor (International) Ag | Novel ferroportin inhibitors |
-
2016
- 2016-10-21 AU AU2016342310A patent/AU2016342310B2/en active Active
- 2016-10-21 CA CA3002418A patent/CA3002418C/en active Active
- 2016-10-21 HU HUE16797462A patent/HUE073266T2/hu unknown
- 2016-10-21 SI SI201631922T patent/SI3365339T1/sl unknown
- 2016-10-21 AU AU2016342309A patent/AU2016342309B2/en active Active
- 2016-10-21 SM SM20250391T patent/SMT202500391T1/it unknown
- 2016-10-21 KR KR1020187011524A patent/KR102352829B1/ko active Active
- 2016-10-21 MY MYPI2018000549A patent/MY198246A/en unknown
- 2016-10-21 CO CONC2018/0004165A patent/CO2018004165A2/es unknown
- 2016-10-21 EP EP16797462.5A patent/EP3365339B1/en active Active
- 2016-10-21 LT LTEPPCT/EP2016/075306T patent/LT3365339T/lt unknown
- 2016-10-21 RS RS20251013A patent/RS67304B1/sr unknown
- 2016-10-21 MA MA44474A patent/MA44474B1/fr unknown
- 2016-10-21 FI FIEP16797462.5T patent/FI3365339T3/fi active
- 2016-10-21 JP JP2018520089A patent/JP6710754B2/ja active Active
- 2016-10-21 DK DK16797462.5T patent/DK3365339T3/da active
- 2016-10-21 TW TW105134089A patent/TWI722031B/zh active
- 2016-10-21 US US15/769,148 patent/US10364239B2/en active Active
- 2016-10-21 SG SG10202005377VA patent/SG10202005377VA/en unknown
- 2016-10-21 SG SG11201802665VA patent/SG11201802665VA/en unknown
- 2016-10-21 HR HRP20251038TT patent/HRP20251038T1/hr unknown
- 2016-10-21 WO PCT/EP2016/075305 patent/WO2017068089A2/en not_active Ceased
- 2016-10-21 SG SG11201802480YA patent/SG11201802480YA/en unknown
- 2016-10-21 PL PL16797462.5T patent/PL3365339T3/pl unknown
- 2016-10-21 CN CN201680061941.3A patent/CN108290878B/zh active Active
- 2016-10-21 EP EP16784510.6A patent/EP3364967A2/en active Pending
- 2016-10-21 CA CA3002416A patent/CA3002416C/en active Active
- 2016-10-21 UA UAA201805740A patent/UA123219C2/uk unknown
- 2016-10-21 BR BR112018007977-4A patent/BR112018007977B1/pt active IP Right Grant
- 2016-10-21 PT PT167974625T patent/PT3365339T/pt unknown
- 2016-10-21 WO PCT/EP2016/075306 patent/WO2017068090A1/en not_active Ceased
- 2016-10-21 MX MX2018004882A patent/MX390514B/es unknown
- 2016-10-21 JP JP2018520090A patent/JP6810988B2/ja active Active
- 2016-10-21 US US15/768,025 patent/US10738041B2/en active Active
- 2016-10-21 CN CN202210353448.6A patent/CN114668761B/zh active Active
- 2016-10-21 ES ES16797462T patent/ES3039644T3/es active Active
- 2016-10-21 PE PE2018000572A patent/PE20181496A1/es unknown
- 2016-10-23 JO JOP/2016/0229A patent/JO3780B1/ar active
-
2018
- 2018-03-15 IL IL258159A patent/IL258159B/en unknown
- 2018-03-15 IL IL258158A patent/IL258158B2/en unknown
- 2018-04-06 PH PH12018500769A patent/PH12018500769A1/en unknown
- 2018-04-20 MX MX2021015106A patent/MX2021015106A/es unknown
- 2018-04-20 CL CL2018001031A patent/CL2018001031A1/es unknown
-
2019
- 2019-06-12 US US16/438,596 patent/US11001579B2/en active Active
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2020
- 2020-05-27 JP JP2020091830A patent/JP6967112B2/ja active Active
- 2020-11-24 AU AU2020277121A patent/AU2020277121C1/en active Active
- 2020-12-03 US US17/110,465 patent/US11066399B2/en active Active
-
2021
- 2021-06-07 US US17/340,692 patent/US20220363675A1/en not_active Abandoned
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