JP2018535203A5 - - Google Patents
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- JP2018535203A5 JP2018535203A5 JP2018520089A JP2018520089A JP2018535203A5 JP 2018535203 A5 JP2018535203 A5 JP 2018535203A5 JP 2018520089 A JP2018520089 A JP 2018520089A JP 2018520089 A JP2018520089 A JP 2018520089A JP 2018535203 A5 JP2018535203 A5 JP 2018535203A5
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- Japan
- Prior art keywords
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- compound according
- iron
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 0 CC(C)(*C(C)(*)N(*)C(C1*=*(*N(*)*c2nc(C=CC(C)(*)C=C3)c3[n]2)*=*1)=O)C1=NC=CC(C)(*)C=C1 Chemical compound CC(C)(*C(C)(*)N(*)C(C1*=*(*N(*)*c2nc(C=CC(C)(*)C=C3)c3[n]2)*=*1)=O)C1=NC=CC(C)(*)C=C1 0.000 description 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2020091830A JP6967112B2 (ja) | 2015-10-23 | 2020-05-27 | 新規なフェロポーチン阻害剤 |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP15191176.5 | 2015-10-23 | ||
| EP15191179.9 | 2015-10-23 | ||
| EP15191179 | 2015-10-23 | ||
| EP15191176 | 2015-10-23 | ||
| PCT/EP2016/075306 WO2017068090A1 (en) | 2015-10-23 | 2016-10-21 | Novel ferroportin inhibitors |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020091830A Division JP6967112B2 (ja) | 2015-10-23 | 2020-05-27 | 新規なフェロポーチン阻害剤 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018535203A JP2018535203A (ja) | 2018-11-29 |
| JP2018535203A5 true JP2018535203A5 (enExample) | 2019-03-14 |
| JP6710754B2 JP6710754B2 (ja) | 2020-06-17 |
Family
ID=57178421
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018520090A Active JP6810988B2 (ja) | 2015-10-23 | 2016-10-21 | 新規なフェロポーチン阻害剤 |
| JP2018520089A Active JP6710754B2 (ja) | 2015-10-23 | 2016-10-21 | 新規なフェロポーチン阻害剤 |
| JP2020091830A Active JP6967112B2 (ja) | 2015-10-23 | 2020-05-27 | 新規なフェロポーチン阻害剤 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018520090A Active JP6810988B2 (ja) | 2015-10-23 | 2016-10-21 | 新規なフェロポーチン阻害剤 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020091830A Active JP6967112B2 (ja) | 2015-10-23 | 2020-05-27 | 新規なフェロポーチン阻害剤 |
Country Status (30)
| Country | Link |
|---|---|
| US (5) | US10364239B2 (enExample) |
| EP (2) | EP3365339B1 (enExample) |
| JP (3) | JP6810988B2 (enExample) |
| KR (1) | KR102352829B1 (enExample) |
| CN (2) | CN108290878B (enExample) |
| AU (3) | AU2016342309B2 (enExample) |
| BR (1) | BR112018007977B1 (enExample) |
| CA (2) | CA3002416C (enExample) |
| CL (1) | CL2018001031A1 (enExample) |
| CO (1) | CO2018004165A2 (enExample) |
| DK (1) | DK3365339T3 (enExample) |
| ES (1) | ES3039644T3 (enExample) |
| FI (1) | FI3365339T3 (enExample) |
| HR (1) | HRP20251038T1 (enExample) |
| IL (2) | IL258158B2 (enExample) |
| JO (1) | JO3780B1 (enExample) |
| LT (1) | LT3365339T (enExample) |
| MA (1) | MA44474B1 (enExample) |
| MX (2) | MX390514B (enExample) |
| MY (1) | MY198246A (enExample) |
| PE (1) | PE20181496A1 (enExample) |
| PH (1) | PH12018500769A1 (enExample) |
| PL (1) | PL3365339T3 (enExample) |
| PT (1) | PT3365339T (enExample) |
| RS (1) | RS67304B1 (enExample) |
| SG (3) | SG11201802480YA (enExample) |
| SM (1) | SMT202500391T1 (enExample) |
| TW (1) | TWI722031B (enExample) |
| UA (1) | UA123219C2 (enExample) |
| WO (2) | WO2017068090A1 (enExample) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT2968443T (pt) | 2013-03-15 | 2021-12-28 | Protagonist Therapeutics Inc | Análogos de hepcidina e seus usos |
| JP6810988B2 (ja) * | 2015-10-23 | 2021-01-13 | ヴィフォール （インターナショナル） アクチェンゲゼルシャフトＶｉｆｏｒ （Ｉｎｔｅｒｎａｔｉｏｎａｌ） ＡＧ | 新規なフェロポーチン阻害剤 |
| JOP20180036A1 (ar) * | 2017-04-18 | 2019-01-30 | Vifor Int Ag | أملاح لمثبطات فروبورتين جديدة |
| CN108314687A (zh) * | 2017-12-27 | 2018-07-24 | 重庆文理学院 | 1,2-二氢苯并[4,5]咪唑并[1,2-a]吡嗪-3（4H）-酮衍生物的合成 |
| EP4501952A3 (en) | 2018-02-08 | 2025-04-16 | Protagonist Therapeutics, Inc. | Conjugated hepcidin mimetics |
| EP3788065B1 (en) | 2018-04-30 | 2025-08-27 | The Children's Hospital Of Philadelphia | Improving anemias by combining agents |
| EP3894416B1 (en) | 2018-12-13 | 2022-11-09 | Global Blood Therapeutics, Inc. | Ferroportin inhibitors and methods of use |
| TW202102478A (zh) | 2019-04-01 | 2021-01-16 | 瑞士商威佛（國際）股份有限公司 | 新穎的鐵螯合物 |
| US20220273634A1 (en) * | 2019-07-19 | 2022-09-01 | Vifor (International) Ag | Ferroportin-Inhibitors For The Use In The Treatment Of Transfusion-Dependent Beta-Thalassemia (TDT) |
| US20220323416A1 (en) | 2019-07-19 | 2022-10-13 | Vifor (International) Ag | Ferroportin-Inhibitors For The Use In The Prevention And Treatment Of Kidney Injuries |
| EP3782702A1 (en) * | 2019-08-21 | 2021-02-24 | AC BioScience SA | Compounds and use thereof for the treatment of infectious diseases and cancer |
| BR112022003999A2 (pt) | 2019-09-03 | 2022-05-31 | Protagonist Therapeutics Inc | Miméticos de hepcidina conjugados |
| CA3154524A1 (en) | 2019-10-22 | 2021-04-21 | Vania Manolova | Methods and compositions for treating sickle cell disease with a ferroportin inhibitor (vit-2763) |
| CN115362154A (zh) * | 2020-03-24 | 2022-11-18 | 威佛（国际）股份公司 | 膜铁转运蛋白抑制剂的制备方法 |
| GB202012969D0 (en) * | 2020-08-19 | 2020-09-30 | Univ Of Oxford | Inhibitor compounds |
| US20250268878A1 (en) * | 2021-01-20 | 2025-08-28 | Vifor (International) Ag | Ferroportin-inhibitors for the use in the treatment of myelodysplastic syndromes (mds) |
| WO2022173818A1 (en) * | 2021-02-09 | 2022-08-18 | University Of Virginia Patent Foundation | Use of biliverdin reductase b inhibitors to allow malaria eradication in patients with g6pd deficiency |
| KR20230163464A (ko) * | 2021-03-26 | 2023-11-30 | 키에시 파르마슈티시 엣스. 피. 에이. | Ddr 억제제로서 테트라하이드로싸이에노 피리딘 유도체 |
| TW202304896A (zh) | 2021-04-22 | 2023-02-01 | 瑞士商威佛（國際）股份有限公司 | 經修飾的膜鐵運輸蛋白(ferroportin)抑制劑 |
| JP2024534538A (ja) | 2021-09-21 | 2024-09-20 | ビフォー （インターナショナル） エージー | Ｎ－置換フェロポーチン阻害剤 |
| CN120322439A (zh) | 2022-10-21 | 2025-07-15 | 威佛（国际）股份公司 | 双环铁转运蛋白抑制剂 |
| CN115974864B (zh) * | 2022-12-29 | 2025-09-16 | 苏州汉德创宏生化科技有限公司 | 一种2-(3-氮杂环丁基)噻唑盐的合成方法 |
| AU2024244929A1 (en) | 2023-03-27 | 2025-09-11 | New York Blood Center, Inc. | Compounds and compositions for use in stem cell transplantation |
| WO2025003139A1 (en) | 2023-06-26 | 2025-01-02 | Vifor (International) Ag | Ferroportin-inhibitors for the use in the treatment of hereditary haemochromatosis (hh) |
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| CH479616A (de) * | 1959-12-24 | 1969-10-15 | Ciba Geigy | Verfahren zur Herstellung neuer Methylidenverbindungen |
| TW533205B (en) | 1996-06-25 | 2003-05-21 | Novartis Ag | Substituted 3,5-diphenyl-l,2,4-triazoles and their pharmaceutical composition |
| US5922761A (en) | 1996-09-06 | 1999-07-13 | Medinox, Inc. | Methods for in vivo reduction of iron levels and compositions useful therefor |
| AR009655A1 (es) | 1996-12-10 | 2000-04-26 | Novartis Ag | Una composicion parenteralmente inyectable, un metodo para su preparacion, metodos para el tratamiento de enfermedades, una modificacion decristal de 1-decansulfonato de desferrioxamina, su uso, un proceso para la produccion de dicha modificacion de cristal y una preparacion farmaceutica que |
| WO1998027108A2 (en) | 1996-12-16 | 1998-06-25 | Fujisawa Pharmaceutical Co., Ltd. | New amide compounds and their use as nitric oxide synthase inhibitors |
| CA2368026A1 (en) | 1999-03-22 | 2000-09-28 | Bi-Huang Hu | Oxazole and thiazole combinatorial libraries |
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| EP1074254A3 (en) | 1999-07-20 | 2002-09-11 | MEDIS S.r.l. Medical Infusion Systems | Use of plant polyphenols with vitamines for treating iron overload |
| WO2002022599A2 (en) * | 2000-09-15 | 2002-03-21 | Anormed Inc. | Chemokine receptor binding heterocyclic compounds |
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| MXPA04002785A (es) * | 2001-09-24 | 2004-07-29 | Elan Pharm Inc | Aminas sustituidas para tratamiento de enfermedad de alzheimer. |
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| WO2005014576A1 (ja) | 2003-08-12 | 2005-02-17 | Takeda Pharmaceutical Company Limited | イソキノリノン誘導体、その製造法および用途 |
| DE10356409B4 (de) | 2003-11-28 | 2006-12-28 | Biofrontera Discovery Gmbh | Neues Arzneimittel Oxachelin und Derivate |
| FR2870271B1 (fr) | 2004-05-11 | 2008-03-14 | Bruno Merand | Procede de construction d'une maison en bois et moyens pour la mise en oeuvre du procede. |
| WO2006004841A2 (en) * | 2004-06-29 | 2006-01-12 | The Scripps Research Institute | Galanin agonists |
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| JP2008007405A (ja) | 2004-12-07 | 2008-01-17 | Takeda Chem Ind Ltd | カルボキサミド誘導体 |
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| PL3210627T3 (pl) * | 2012-07-12 | 2023-04-17 | Hangzhou Dac Biotech Co., Ltd | Koniugaty zawierające cząsteczki wiążące się z komórką i środek cytotoksyczny |
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| WO2015051362A1 (en) * | 2013-10-04 | 2015-04-09 | Illinois Institute Of Technology | Multifunctional chelators, complexes, and compositions thereof, and methods of using same |
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| CN107249580A (zh) * | 2014-12-05 | 2017-10-13 | An2H探索有限公司 | 帕金连接酶活化方法和组合物 |
| JP6810988B2 (ja) * | 2015-10-23 | 2021-01-13 | ヴィフォール （インターナショナル） アクチェンゲゼルシャフトＶｉｆｏｒ （Ｉｎｔｅｒｎａｔｉｏｎａｌ） ＡＧ | 新規なフェロポーチン阻害剤 |
-
2016
- 2016-10-21 JP JP2018520090A patent/JP6810988B2/ja active Active
- 2016-10-21 CN CN201680061941.3A patent/CN108290878B/zh active Active
- 2016-10-21 SM SM20250391T patent/SMT202500391T1/it unknown
- 2016-10-21 JP JP2018520089A patent/JP6710754B2/ja active Active
- 2016-10-21 ES ES16797462T patent/ES3039644T3/es active Active
- 2016-10-21 CA CA3002416A patent/CA3002416C/en active Active
- 2016-10-21 BR BR112018007977-4A patent/BR112018007977B1/pt active IP Right Grant
- 2016-10-21 AU AU2016342309A patent/AU2016342309B2/en active Active
- 2016-10-21 PL PL16797462.5T patent/PL3365339T3/pl unknown
- 2016-10-21 DK DK16797462.5T patent/DK3365339T3/da active
- 2016-10-21 RS RS20251013A patent/RS67304B1/sr unknown
- 2016-10-21 SG SG11201802480YA patent/SG11201802480YA/en unknown
- 2016-10-21 PE PE2018000572A patent/PE20181496A1/es unknown
- 2016-10-21 EP EP16797462.5A patent/EP3365339B1/en active Active
- 2016-10-21 CA CA3002418A patent/CA3002418C/en active Active
- 2016-10-21 TW TW105134089A patent/TWI722031B/zh active
- 2016-10-21 MX MX2018004882A patent/MX390514B/es unknown
- 2016-10-21 MY MYPI2018000549A patent/MY198246A/en unknown
- 2016-10-21 CO CONC2018/0004165A patent/CO2018004165A2/es unknown
- 2016-10-21 US US15/769,148 patent/US10364239B2/en active Active
- 2016-10-21 LT LTEPPCT/EP2016/075306T patent/LT3365339T/lt unknown
- 2016-10-21 WO PCT/EP2016/075306 patent/WO2017068090A1/en not_active Ceased
- 2016-10-21 FI FIEP16797462.5T patent/FI3365339T3/fi active
- 2016-10-21 MA MA44474A patent/MA44474B1/fr unknown
- 2016-10-21 UA UAA201805740A patent/UA123219C2/uk unknown
- 2016-10-21 EP EP16784510.6A patent/EP3364967A2/en active Pending
- 2016-10-21 HR HRP20251038TT patent/HRP20251038T1/hr unknown
- 2016-10-21 PT PT167974625T patent/PT3365339T/pt unknown
- 2016-10-21 KR KR1020187011524A patent/KR102352829B1/ko active Active
- 2016-10-21 SG SG10202005377VA patent/SG10202005377VA/en unknown
- 2016-10-21 AU AU2016342310A patent/AU2016342310B2/en active Active
- 2016-10-21 WO PCT/EP2016/075305 patent/WO2017068089A2/en not_active Ceased
- 2016-10-21 US US15/768,025 patent/US10738041B2/en active Active
- 2016-10-21 CN CN202210353448.6A patent/CN114668761B/zh active Active
- 2016-10-21 SG SG11201802665VA patent/SG11201802665VA/en unknown
- 2016-10-23 JO JOP/2016/0229A patent/JO3780B1/ar active
-
2018
- 2018-03-15 IL IL258158A patent/IL258158B2/en unknown
- 2018-03-15 IL IL258159A patent/IL258159B/en unknown
- 2018-04-06 PH PH12018500769A patent/PH12018500769A1/en unknown
- 2018-04-20 CL CL2018001031A patent/CL2018001031A1/es unknown
- 2018-04-20 MX MX2021015106A patent/MX2021015106A/es unknown
-
2019
- 2019-06-12 US US16/438,596 patent/US11001579B2/en active Active
-
2020
- 2020-05-27 JP JP2020091830A patent/JP6967112B2/ja active Active
- 2020-11-24 AU AU2020277121A patent/AU2020277121C1/en active Active
- 2020-12-03 US US17/110,465 patent/US11066399B2/en active Active
-
2021
- 2021-06-07 US US17/340,692 patent/US20220363675A1/en not_active Abandoned
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