DK1656139T3 - Aryldicarboxamider - Google Patents
AryldicarboxamiderInfo
- Publication number
- DK1656139T3 DK1656139T3 DK04742005.4T DK04742005T DK1656139T3 DK 1656139 T3 DK1656139 T3 DK 1656139T3 DK 04742005 T DK04742005 T DK 04742005T DK 1656139 T3 DK1656139 T3 DK 1656139T3
- Authority
- DK
- Denmark
- Prior art keywords
- sub
- sup
- aryl
- alkyl
- carboxy
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/166—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the carbon of a carboxamide group directly attached to the aromatic ring, e.g. procainamide, procarbazine, metoclopramide, labetalol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/426—1,3-Thiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/28—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
- C07C237/42—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having nitrogen atoms of amino groups bound to the carbon skeleton of the acid part, further acylated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
- C07C255/49—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C255/57—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and carboxyl groups, other than cyano groups, bound to the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D277/30—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
- C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Diabetes (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Pain & Pain Management (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Child & Adolescent Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Polyamides (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP03102236 | 2003-07-21 | ||
US51782403P | 2003-11-06 | 2003-11-06 | |
PCT/EP2004/051558 WO2005011685A1 (en) | 2003-07-21 | 2004-07-20 | Aryl dicarboxamides |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1656139T3 true DK1656139T3 (da) | 2012-01-30 |
Family
ID=34924079
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK04742005.4T DK1656139T3 (da) | 2003-07-21 | 2004-07-20 | Aryldicarboxamider |
Country Status (12)
Country | Link |
---|---|
US (1) | US7365225B2 (da) |
EP (1) | EP1656139B1 (da) |
JP (1) | JP2006528157A (da) |
AT (1) | ATE526964T1 (da) |
AU (1) | AU2004260831A1 (da) |
CA (1) | CA2529662A1 (da) |
DK (1) | DK1656139T3 (da) |
ES (1) | ES2375132T3 (da) |
PL (1) | PL1656139T3 (da) |
PT (1) | PT1656139E (da) |
SI (1) | SI1656139T1 (da) |
WO (1) | WO2005011685A1 (da) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7589232B2 (en) * | 2003-07-21 | 2009-09-15 | Laboratories Serono S.A. | Alkynyl aryl carboxamides |
JP2008007405A (ja) * | 2004-12-07 | 2008-01-17 | Takeda Chem Ind Ltd | カルボキサミド誘導体 |
CA2613458A1 (en) * | 2005-07-12 | 2007-01-18 | Acadia Pharmaceuticals Inc. | Compounds with activity at retinoic acid receptors |
ITRM20050390A1 (it) * | 2005-07-22 | 2007-01-23 | Giuliani Spa | Composti e loro sali specifici per i recettori ppar ed i recettori per l'egf e loro uso in campo medico. |
CN101282936B (zh) * | 2005-10-07 | 2012-05-16 | 橘生药品工业株式会社 | 氮化杂环化合物及包含其的药物组合物 |
HUE027022T2 (en) | 2007-08-13 | 2016-08-29 | Monsanto Technology Llc | Preparations and procedures for controlling nematodes |
DE102007061764A1 (de) | 2007-12-20 | 2009-06-25 | Bayer Healthcare Ag | Anellierte Cyanopyridine und ihre Verwendung |
BR112013011188B1 (pt) * | 2010-11-05 | 2022-01-04 | Senomyx, Inc | Método não-médico para modular canal potencial de receptor transiente de melastina 8 (trpm8), método não-médico para modular a sensação de resfriamento de uma composição, método não-médico para induzir uma sensação de resfriamento em um humano ou animal e composto |
RU2745616C1 (ru) | 2015-10-01 | 2021-03-29 | Сеномикс, Инк. | Соединения, используемые в качестве модуляторов trpm8 |
TWI722031B (zh) | 2015-10-23 | 2021-03-21 | 瑞士商威佛(國際)股份有限公司 | 新穎的膜鐵運輸蛋白(ferroportin)抑制劑 |
JOP20180036A1 (ar) | 2017-04-18 | 2019-01-30 | Vifor Int Ag | أملاح لمثبطات فروبورتين جديدة |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HUP0201033A3 (en) * | 1999-05-17 | 2003-03-28 | Novo Nordisk As | Glucagon antagonists/inverse agonists, process for their preparation and their use |
JP2004501897A (ja) * | 2000-06-23 | 2004-01-22 | ノボ ノルディスク アクティーゼルスカブ | グルカゴン拮抗薬/逆作用薬 |
US6972340B2 (en) * | 2000-08-29 | 2005-12-06 | Abbott Laboratories | Selective protein tyrosine phosphatatase inhibitors |
DE10044792A1 (de) * | 2000-09-11 | 2002-04-04 | Bayer Ag | Substituierte Phenylcyclohexancarbonsäureamide und ihre Verwendung |
AU2002223501A1 (en) * | 2000-11-17 | 2002-05-27 | Agouron Pharmaceuticals, Inc. | Glucagon antagonists/inverse agonists |
AU2002223500A1 (en) * | 2000-11-17 | 2002-05-27 | Novo-Nordisk A/S | Glucagon antagonists/inverse agonists |
US6878743B2 (en) | 2001-09-18 | 2005-04-12 | Sunesis Pharmaceuticals, Inc. | Small molecule inhibitors of caspases |
MXPA04007253A (es) * | 2002-01-29 | 2004-10-29 | Applied Research Systems | Derivados de metilenamidas sustituidos como moduladores de proteina tirosina fosfatasas (ptp). |
US7589232B2 (en) * | 2003-07-21 | 2009-09-15 | Laboratories Serono S.A. | Alkynyl aryl carboxamides |
-
2004
- 2004-07-20 PL PL04742005T patent/PL1656139T3/pl unknown
- 2004-07-20 EP EP04742005A patent/EP1656139B1/en not_active Expired - Lifetime
- 2004-07-20 SI SI200431770T patent/SI1656139T1/sl unknown
- 2004-07-20 JP JP2006520836A patent/JP2006528157A/ja not_active Withdrawn
- 2004-07-20 US US10/565,557 patent/US7365225B2/en not_active Expired - Fee Related
- 2004-07-20 WO PCT/EP2004/051558 patent/WO2005011685A1/en active Application Filing
- 2004-07-20 ES ES04742005T patent/ES2375132T3/es not_active Expired - Lifetime
- 2004-07-20 DK DK04742005.4T patent/DK1656139T3/da active
- 2004-07-20 CA CA002529662A patent/CA2529662A1/en not_active Abandoned
- 2004-07-20 AU AU2004260831A patent/AU2004260831A1/en not_active Abandoned
- 2004-07-20 AT AT04742005T patent/ATE526964T1/de active
- 2004-07-20 PT PT04742005T patent/PT1656139E/pt unknown
Also Published As
Publication number | Publication date |
---|---|
PT1656139E (pt) | 2011-11-04 |
EP1656139A1 (en) | 2006-05-17 |
ES2375132T3 (es) | 2012-02-27 |
CA2529662A1 (en) | 2005-02-10 |
PL1656139T3 (pl) | 2012-03-30 |
JP2006528157A (ja) | 2006-12-14 |
WO2005011685A1 (en) | 2005-02-10 |
US7365225B2 (en) | 2008-04-29 |
EP1656139B1 (en) | 2011-10-05 |
ATE526964T1 (de) | 2011-10-15 |
US20060189583A1 (en) | 2006-08-24 |
SI1656139T1 (sl) | 2011-12-30 |
AU2004260831A1 (en) | 2005-02-10 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CA2411778A1 (en) | Organic compounds | |
EA200870489A1 (ru) | Пиперидинилзамещённые пирролидиноны в качестве ингибиторов 11-бета-гидроксистероид дегидрогеназы 1 | |
D'hooghe et al. | A novel entry toward 2-imino-1, 3-thiazolidines and 2-imino-1, 3-thiazolines by ring transformation of 2-(thiocyanomethyl) aziridines | |
DK1656139T3 (da) | Aryldicarboxamider | |
UY26089A1 (es) | Inhibidores de la sorbitol deshidrogenasa | |
ATE557030T1 (de) | Kondensiertes heterocyclisches derivat, dieses enthaltende medizinische zusammensetzung und deren medizinische verwendung | |
DK1807072T3 (da) | Cycloalkyllactamderivater som inhibitorer af 11-beta-hydroxysteroid-dehydrogenase 1 | |
EA200601660A1 (ru) | Ингибирующие mtp арилпиперидины или пиперазины, замещенные 5-членными гетероциклами | |
EA200870460A1 (ru) | Производные циклогексилпиразол-лактама в качестве ингибиторов 11-бета-гидроксистероиддегидрогеназы 1 | |
ATE472542T1 (de) | 11-beta-hydroxysteroid-dehydrogenase-1-hemmer | |
DK2021337T3 (da) | Inhibitorer af 11-beta-hydroxysteroid-dehydrogenase-1 | |
ATE471311T1 (de) | Inhibitoren von11-beta- hydroxysteroiddehydrogenase 1 | |
DE602007007614D1 (de) | Substituierte pyrrolidinone als hemmer von 11-beta-hydroxysteroiddehydrogenase 1 | |
RU2011106374A (ru) | Циклические ингибиторы 11бета-гидроксистероид-дегидрогеназы 1 | |
EP1829865A3 (en) | O-Cyclopropyl-carboxanilides and their use as fungicides | |
PE20070137A1 (es) | Compuestos derivados de benzamidina como moduladores de las hidroxiesteroide deshidrogenasas | |
NZ602099A (en) | Stat3 inhibitor containing quinolinecarboxamide derivative as active ingredient | |
WO2003011880A1 (fr) | Derive de glucopyranosyloxybenzylbenzene, composition medicinale contenant ce derive, usage medicinal de cette composition et produit intermediaire pour produire cette composition | |
ATE455772T1 (de) | Alkinylarylcarbonsäureamide | |
WO2008142859A1 (ja) | 新規なスピロオキシインドール化合物及びこれを含有する医薬 | |
NO20061614L (no) | Benzimidazolacetonitriler | |
EA200400882A1 (ru) | ЗАМЕЩЁННЫЕ ПРОИЗВОДНЫЕ МЕТИЛЕНАМИДА В КАЧЕСТВЕ МОДУЛЯТОРОВ ПРОТЕИНТИРОЗИНФОСФАТАЗ ( PTPs ) | |
AR033349A1 (es) | Compuesto heterociclico y composicion farmaceutica, agente hipoglucemico, agente hipolipidemico, mejorador de la resistencia a la insulina, agente terapeutico para las complicaciones de origen diabetico y agente terapeutico para la diabetes que los comprenden | |
EA200970170A1 (ru) | Производные 4-триметиламмоний-3-аминобутирата и 4-триметилфосфоний-3-аминобутирата как ингибиторы срт | |
EA200601120A1 (ru) | N-арилпиперидинзамещённые бифинилкарбоксамиды в качестве ингибиторов аполипопротеина в |