NO20061614L - Benzimidazolacetonitriler - Google Patents
BenzimidazolacetonitrilerInfo
- Publication number
- NO20061614L NO20061614L NO20061614A NO20061614A NO20061614L NO 20061614 L NO20061614 L NO 20061614L NO 20061614 A NO20061614 A NO 20061614A NO 20061614 A NO20061614 A NO 20061614A NO 20061614 L NO20061614 L NO 20061614L
- Authority
- NO
- Norway
- Prior art keywords
- acetonitriles
- benzimidazole
- group
- alkynyl
- alkenyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Abstract
Foreliggende oppfinnelse angår benzimidazolacetonitriler så vel som farmasøytiske formuleringer som inneholder slike benzimidazolacetonitriler med formel (I). Nevnte benzimidazolacetonitriler kan brukes for behandling av metabolske lidelser som er kontrollert eller forårsaket av insulinresistens eller hyperglykemi, og som omfatter diabetes II, utilfredsstillende glukosetoleranse, insulinresistens, overvekt og polycystisk eggstokksyndrom (PCOS) (I). Den foreliggende oppfinnelsen angår videre fremgangsmåter for fremstilling av benzimidazolacetonitriler, hvor G er pyrimidinyl, L er en aminogruppe eller en 3-8-leddet heterosykloalkylgruppe som inneholder minst ett heteroatom valgt fra N, O eller S, eller L er en acylaminogruppe; R1 er valgt fra gruppen bestående av hydrogen, sulfonyl, amino, karboksy, aminokarbonyl, C1-C6-alkyl, C2-C6-alkenyl, C2-C6-alkynyl eller C1-C6-alkoksy, aryl, halogen, cyano eller hydroksy; R2 er valgt fra gruppen bestående av hydrogen, C1-C6-alkyl, C2-C6-alkenyl, C2-C6-alkynyl, eller C1-C6-alkoksy.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP03102741 | 2003-09-12 | ||
PCT/EP2004/052137 WO2005026155A1 (en) | 2003-09-12 | 2004-09-10 | Benzimidazole acetonitriles |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20061614L true NO20061614L (no) | 2006-04-10 |
Family
ID=34306922
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20061614A NO20061614L (no) | 2003-09-12 | 2006-04-10 | Benzimidazolacetonitriler |
Country Status (7)
Country | Link |
---|---|
EP (1) | EP1667995A1 (no) |
JP (1) | JP2007505085A (no) |
AU (1) | AU2004272306A1 (no) |
CA (1) | CA2534317A1 (no) |
IL (1) | IL174135A0 (no) |
NO (1) | NO20061614L (no) |
WO (1) | WO2005026155A1 (no) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7713973B2 (en) | 2004-10-15 | 2010-05-11 | Takeda Pharmaceutical Company Limited | Kinase inhibitors |
JP2009506069A (ja) | 2005-08-26 | 2009-02-12 | ブレインセルス,インコーポレイティド | ムスカリン性受容体調節による神経発生 |
EP2258358A3 (en) | 2005-08-26 | 2011-09-07 | Braincells, Inc. | Neurogenesis with acetylcholinesterase inhibitor |
US8119655B2 (en) | 2005-10-07 | 2012-02-21 | Takeda Pharmaceutical Company Limited | Kinase inhibitors |
JP2009512711A (ja) | 2005-10-21 | 2009-03-26 | ブレインセルス,インコーポレイティド | Pde阻害による神経新生の調節 |
AU2006308889A1 (en) | 2005-10-31 | 2007-05-10 | Braincells, Inc. | GABA receptor mediated modulation of neurogenesis |
US20100216734A1 (en) | 2006-03-08 | 2010-08-26 | Braincells, Inc. | Modulation of neurogenesis by nootropic agents |
AU2007249399A1 (en) | 2006-05-09 | 2007-11-22 | Braincells, Inc. | Neurogenesis by modulating angiotensin |
US20100184806A1 (en) | 2006-09-19 | 2010-07-22 | Braincells, Inc. | Modulation of neurogenesis by ppar agents |
GEP20135728B (en) | 2006-10-09 | 2013-01-25 | Takeda Pharmaceuticals Co | Kinase inhibitors |
WO2010099217A1 (en) | 2009-02-25 | 2010-09-02 | Braincells, Inc. | Modulation of neurogenesis using d-cycloserine combinations |
CN113281309B (zh) * | 2021-05-17 | 2022-03-01 | 深圳市罗湖区人民医院 | 一种毒死蜱、多菌灵、阿特拉津三合一检测方法 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1110957A1 (en) * | 1999-12-24 | 2001-06-27 | Applied Research Systems ARS Holding N.V. | Benzazole derivatives and their use as JNK modulators |
AU2001295026B2 (en) * | 2000-09-06 | 2008-04-03 | Novartis Vaccines And Diagnostics, Inc. | Inhibitors of glycogen synthase kinase 3 |
-
2004
- 2004-09-10 JP JP2006525833A patent/JP2007505085A/ja active Pending
- 2004-09-10 AU AU2004272306A patent/AU2004272306A1/en not_active Abandoned
- 2004-09-10 WO PCT/EP2004/052137 patent/WO2005026155A1/en active Application Filing
- 2004-09-10 EP EP04766767A patent/EP1667995A1/en not_active Withdrawn
- 2004-09-10 CA CA002534317A patent/CA2534317A1/en not_active Abandoned
-
2006
- 2006-03-06 IL IL174135A patent/IL174135A0/en unknown
- 2006-04-10 NO NO20061614A patent/NO20061614L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
WO2005026155A1 (en) | 2005-03-24 |
IL174135A0 (en) | 2006-08-01 |
EP1667995A1 (en) | 2006-06-14 |
AU2004272306A1 (en) | 2005-03-24 |
CA2534317A1 (en) | 2005-03-24 |
JP2007505085A (ja) | 2007-03-08 |
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Legal Events
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CREP | Change of representative |
Representative=s name: ONSAGERS AS, POSTBOKS 6963 ST OLAVS PLASS, 0130 OS |
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FC2A | Withdrawal, rejection or dismissal of laid open patent application |