JP2017534654A5 - - Google Patents
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- Publication number
- JP2017534654A5 JP2017534654A5 JP2017525909A JP2017525909A JP2017534654A5 JP 2017534654 A5 JP2017534654 A5 JP 2017534654A5 JP 2017525909 A JP2017525909 A JP 2017525909A JP 2017525909 A JP2017525909 A JP 2017525909A JP 2017534654 A5 JP2017534654 A5 JP 2017534654A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- patient
- mediated
- caused
- gardnerella
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 206010040872 skin infection Diseases 0.000 claims 26
- 239000008194 pharmaceutical composition Substances 0.000 claims 19
- 208000002874 Acne Vulgaris Diseases 0.000 claims 15
- 206010000496 acne Diseases 0.000 claims 15
- 230000001404 mediated effect Effects 0.000 claims 15
- 239000012049 topical pharmaceutical composition Substances 0.000 claims 15
- 241000207202 Gardnerella Species 0.000 claims 12
- 150000001875 compounds Chemical class 0.000 claims 12
- 239000003814 drug Substances 0.000 claims 9
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 claims 6
- 208000004926 Bacterial Vaginosis Diseases 0.000 claims 6
- 208000037009 Vaginitis bacterial Diseases 0.000 claims 6
- 150000003839 salts Chemical class 0.000 claims 6
- VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 claims 6
- 241000894006 Bacteria Species 0.000 claims 5
- 241000186427 Cutibacterium acnes Species 0.000 claims 4
- 238000004519 manufacturing process Methods 0.000 claims 4
- 238000011200 topical administration Methods 0.000 claims 4
- 238000011282 treatment Methods 0.000 claims 4
- ODHCTXKNWHHXJC-VKHMYHEASA-N 5-oxo-L-proline Chemical compound OC(=O)[C@@H]1CCC(=O)N1 ODHCTXKNWHHXJC-VKHMYHEASA-N 0.000 claims 3
- QTBSBXVTEAMEQO-UHFFFAOYSA-M Acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 claims 3
- KRKNYBCHXYNGOX-UHFFFAOYSA-K Citrate Chemical compound [O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O KRKNYBCHXYNGOX-UHFFFAOYSA-K 0.000 claims 3
- FEWJPZIEWOKRBE-JCYAYHJZSA-N Dextrotartaric acid Chemical compound OC(=O)[C@H](O)[C@@H](O)C(O)=O FEWJPZIEWOKRBE-JCYAYHJZSA-N 0.000 claims 3
- VZCYOOQTPOCHFL-OWOJBTEDSA-N Fumaric acid Chemical compound OC(=O)\C=C\C(O)=O VZCYOOQTPOCHFL-OWOJBTEDSA-N 0.000 claims 3
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 claims 3
- JVTAAEKCZFNVCJ-UHFFFAOYSA-M Lactate Chemical compound CC(O)C([O-])=O JVTAAEKCZFNVCJ-UHFFFAOYSA-M 0.000 claims 3
- AFVFQIVMOAPDHO-UHFFFAOYSA-N Methanesulfonic acid Chemical compound CS(O)(=O)=O AFVFQIVMOAPDHO-UHFFFAOYSA-N 0.000 claims 3
- 229910019142 PO4 Inorganic materials 0.000 claims 3
- QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 claims 3
- 229940072107 ascorbate Drugs 0.000 claims 3
- 235000010323 ascorbic acid Nutrition 0.000 claims 3
- 239000011668 ascorbic acid Substances 0.000 claims 3
- 201000007032 bacterial conjunctivitis Diseases 0.000 claims 3
- WPYMKLBDIGXBTP-UHFFFAOYSA-N benzoic acid Chemical compound OC(=O)C1=CC=CC=C1 WPYMKLBDIGXBTP-UHFFFAOYSA-N 0.000 claims 3
- AFAXGSQYZLGZPG-UHFFFAOYSA-L ethane-1,2-disulfonate Chemical compound [O-]S(=O)(=O)CCS([O-])(=O)=O AFAXGSQYZLGZPG-UHFFFAOYSA-L 0.000 claims 3
- CCIVGXIOQKPBKL-UHFFFAOYSA-M ethanesulfonate Chemical compound CCS([O-])(=O)=O CCIVGXIOQKPBKL-UHFFFAOYSA-M 0.000 claims 3
- VZCYOOQTPOCHFL-UPHRSURJSA-N maleic acid Chemical compound OC(=O)\C=C/C(O)=O VZCYOOQTPOCHFL-UPHRSURJSA-N 0.000 claims 3
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 claims 3
- 239000010452 phosphate Substances 0.000 claims 3
- 239000000651 prodrug Substances 0.000 claims 3
- 229940002612 prodrug Drugs 0.000 claims 3
- 229940043131 pyroglutamate Drugs 0.000 claims 3
- YGSDEFSMJLZEOE-UHFFFAOYSA-M salicylate Chemical compound OC1=CC=CC=C1C([O-])=O YGSDEFSMJLZEOE-UHFFFAOYSA-M 0.000 claims 3
- 229960001860 salicylate Drugs 0.000 claims 3
- 229940086735 succinate Drugs 0.000 claims 3
- KDYFGRWQOYBRFD-UHFFFAOYSA-L succinate(2-) Chemical compound [O-]C(=O)CCC([O-])=O KDYFGRWQOYBRFD-UHFFFAOYSA-L 0.000 claims 3
- 229940095064 tartrate Drugs 0.000 claims 3
- JOXIMZWYDAKGHI-UHFFFAOYSA-N toluene-4-sulfonic acid Chemical class CC1=CC=C(S(O)(=O)=O)C=C1 JOXIMZWYDAKGHI-UHFFFAOYSA-N 0.000 claims 3
- 241000124008 Mammalia Species 0.000 claims 2
- 241001465754 Metazoa Species 0.000 claims 2
- 230000002265 prevention Effects 0.000 claims 2
- 238000011321 prophylaxis Methods 0.000 claims 2
- 230000000699 topical effect Effects 0.000 claims 2
- 241000207201 Gardnerella vaginalis Species 0.000 claims 1
- 208000015181 infectious disease Diseases 0.000 claims 1
- 229940055019 propionibacterium acne Drugs 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462080212P | 2014-11-14 | 2014-11-14 | |
| US62/080,212 | 2014-11-14 | ||
| PCT/US2015/060851 WO2016077818A1 (en) | 2014-11-14 | 2015-11-16 | Method for treating, preventing, or reducing the risk of skin infection |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2017534654A JP2017534654A (ja) | 2017-11-24 |
| JP2017534654A5 true JP2017534654A5 (enExample) | 2018-12-27 |
Family
ID=55955188
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017525909A Withdrawn JP2017534654A (ja) | 2014-11-14 | 2015-11-16 | 皮膚感染症を処置する、予防する、またはその危険性を低減するための方法 |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US10471046B2 (enExample) |
| EP (1) | EP3217974A4 (enExample) |
| JP (1) | JP2017534654A (enExample) |
| KR (1) | KR20170084200A (enExample) |
| CN (1) | CN107205989A (enExample) |
| AR (1) | AR102666A1 (enExample) |
| AU (1) | AU2015346023A1 (enExample) |
| BR (1) | BR112017009989A2 (enExample) |
| CA (1) | CA2967825A1 (enExample) |
| CL (1) | CL2017001245A1 (enExample) |
| CR (1) | CR20170196A (enExample) |
| EA (1) | EA201791051A1 (enExample) |
| HK (1) | HK1244211A1 (enExample) |
| IL (1) | IL252197A0 (enExample) |
| MX (1) | MX389005B (enExample) |
| NI (1) | NI201700057A (enExample) |
| PH (1) | PH12017500887A1 (enExample) |
| SG (1) | SG11201703856VA (enExample) |
| SV (1) | SV2017005444A (enExample) |
| UY (1) | UY36402A (enExample) |
| WO (1) | WO2016077818A1 (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3307725A1 (en) | 2015-06-11 | 2018-04-18 | Basilea Pharmaceutica International AG | Efflux-pump inhibitors and therapeutic uses thereof |
| JP7174700B2 (ja) * | 2016-12-09 | 2022-11-17 | セルタクシー、エルエルシー | ロイコトリエンａ４ヒドロラーゼの阻害剤としてのモノアミン及びモノアミン誘導体 |
| CN107721943A (zh) * | 2017-10-26 | 2018-02-23 | 沈阳药科大学 | 含联芳基腙结构的噁唑烷酮类化合物及其制备方法 |
| KR20190130243A (ko) | 2018-05-14 | 2019-11-22 | (주)텔리언 | 트러스트 인덱스를 이용한 공유경제 시스템 및 방법 |
| CN114051496B (zh) | 2019-06-25 | 2023-08-04 | 阿米蒂比奥有限公司 | 将联苯基引入新型氨基烷酸的衍生物化合物及包含其的抗真菌药学组合物 |
| CN115677679A (zh) * | 2021-07-26 | 2023-02-03 | 沈阳药科大学 | 含联芳基腙结构的噁唑烷酮化合物及其制备方法和应用 |
Family Cites Families (46)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES332272A1 (es) | 1965-10-20 | 1967-11-16 | Milwaukee Chaplet & Mfg Company Inc | Un dispositivo regulador de programa. |
| GB1185685A (en) | 1966-01-11 | 1970-03-25 | Quinoderm Ltd | Method of Making Pharmaceutical Compositions |
| US3418055A (en) | 1967-04-03 | 1968-12-24 | Schwartzman Gilbert | Pressure operated applicator and cap construction |
| US3410645A (en) | 1967-05-08 | 1968-11-12 | Schwartzman Gilbert | Concave diaphragm applicator |
| US3535422A (en) | 1968-03-11 | 1970-10-20 | Stiefel Laboratories | Stable benzoyl peroxide composition |
| US3669323A (en) | 1969-12-12 | 1972-06-13 | American Can Co | One-way valve insert for collapsible dispensing containers |
| US4056611A (en) | 1973-04-16 | 1977-11-01 | Stiefel Laboratories, Inc. | Therapeutic composition |
| GB1541463A (en) | 1975-10-11 | 1979-02-28 | Lion Dentifrice Co Ltd | Process for prparing a multiple emulsion having a dispersing form of water-phase/oil-phase/water-phase |
| US4620648A (en) | 1982-07-06 | 1986-11-04 | Dab-O-Matic Corp. | Pressure-responsive valve |
| US4522811A (en) | 1982-07-08 | 1985-06-11 | Syntex (U.S.A.) Inc. | Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides |
| US4985459A (en) | 1984-02-08 | 1991-01-15 | Richardson-Vicks, Inc. | Analgesic and anti-inflammatory compositions comprising diphenhydramine and methods of using same |
| US4693623A (en) | 1984-03-02 | 1987-09-15 | Dab-O-Matic Corp. | Pressure-responsive valve for an applicator |
| US4937370A (en) | 1987-06-02 | 1990-06-26 | The Procter & Gamble Company | Novel chromophores, sunscreen compositions and methods for preventing sunburn |
| US4999186A (en) | 1986-06-27 | 1991-03-12 | The Procter & Gamble Company | Novel sunscreen agents, sunscreen compositions and methods for preventing sunburn |
| US4960764A (en) | 1987-03-06 | 1990-10-02 | Richardson-Vicks Inc. | Oil-in-water-in-silicone emulsion compositions |
| US4800197A (en) | 1987-07-17 | 1989-01-24 | Richardson-Vicks Inc. | Anti-acne composition |
| US4891227A (en) | 1988-02-02 | 1990-01-02 | Richardson-Vicks Inc. | Medicated cleansing pads |
| US4891228A (en) | 1988-02-02 | 1990-01-02 | Richardson-Vicks Inc. | Medicated cleansing pads |
| US4919934A (en) | 1989-03-02 | 1990-04-24 | Richardson-Vicks Inc. | Cosmetic sticks |
| US5087445A (en) | 1989-09-08 | 1992-02-11 | Richardson-Vicks, Inc. | Photoprotection compositions having reduced dermal irritation |
| US5073371A (en) | 1990-11-30 | 1991-12-17 | Richardson-Vicks, Inc. | Leave-on facial emulsion compositions |
| US5073372A (en) | 1990-11-30 | 1991-12-17 | Richardson-Vicks, Inc. | Leave-on facial emulsion compositions |
| CA2119556C (en) | 1991-11-01 | 2004-07-06 | Michael Robert Barbachyn | Substituted aryl- and heteroaryl-phenyloxazolidinones |
| US5688792A (en) | 1994-08-16 | 1997-11-18 | Pharmacia & Upjohn Company | Substituted oxazine and thiazine oxazolidinone antimicrobials |
| US6107482A (en) | 1995-03-27 | 2000-08-22 | Isis Pharmaceuticals, Inc. | Nitrogenous macrocyclic compounds |
| DE69628466T2 (de) | 1995-09-22 | 2004-04-01 | Wakunaga Pharmaceutical Co., Ltd. | Zwischenverbindungen zur Herstellung von neunen Pyridoncarbonsäurederivate oder deren Salzen |
| US5763263A (en) | 1995-11-27 | 1998-06-09 | Dehlinger; Peter J. | Method and apparatus for producing position addressable combinatorial libraries |
| US6413981B1 (en) * | 1999-08-12 | 2002-07-02 | Ortho-Mcneil Pharamceutical, Inc. | Bicyclic heterocyclic substituted phenyl oxazolidinone antibacterials, and related compositions and methods |
| MXPA02012045A (es) | 2000-06-05 | 2003-10-15 | Dong A Pharm Co Ltd | Nuevos derivados de oxazolidinona y proceso para su preparacion. |
| US20130059774A1 (en) * | 2000-08-01 | 2013-03-07 | Mahesh Vithalbhai Patel | Efflux pump inhibitors |
| US20030096850A1 (en) * | 2001-10-11 | 2003-05-22 | Ford Charles W. | Treating infections by administration of oxazolidinones |
| AR043050A1 (es) | 2002-09-26 | 2005-07-13 | Rib X Pharmaceuticals Inc | Compuestos heterociclicos bifuncionales y metodos para preparar y usar los mismos |
| KR20060002800A (ko) | 2003-03-05 | 2006-01-09 | 립-엑스 파마슈티칼즈, 인크. | 이관능성 헤테로시클릭 화합물, 및 그의 제조 및 사용 방법 |
| AU2004267007C1 (en) * | 2003-06-03 | 2010-04-29 | Melinta Subsidiary Corp. | Biaryl heterocyclic compounds and methods of making and using the same |
| WO2005012271A2 (en) | 2003-07-29 | 2005-02-10 | Rib-X Pharmaceuticals, Inc. | Process for the synthesis of biaryl oxazolidinones |
| SI1656370T1 (sl) | 2003-06-03 | 2012-12-31 | Rib-X Pharmaceuticals, Inc. | Biarilne heterociklične spojine in postopki za njihovo izdelavo in uporabo |
| WO2005012270A2 (en) | 2003-07-29 | 2005-02-10 | Rib-X Pharmaceuticals, Inc. | Biaryl heterocyclic amines, amides, and sulfur-containing compounds and methods of making and using the same |
| US7129259B2 (en) | 2003-12-17 | 2006-10-31 | Rib-X Pharmaceuticals, Inc. | Halogenated biaryl heterocyclic compounds and methods of making and using the same |
| JP2008508271A (ja) | 2004-07-28 | 2008-03-21 | リブ−エックス ファーマシューティカルズ，インコーポレイテッド | ビアリール複素環式化合物ならびにその化合物を製造および使用する方法 |
| EP2816033A1 (en) | 2004-07-30 | 2014-12-24 | Abbvie Inc. | Preparation of pyridonecarboxylic acid antibacterials |
| MX2007004111A (es) | 2004-10-08 | 2007-06-14 | Abbott Lab | Sal y formas cristalinas de la misma de un farmaco. |
| HRP20120502T1 (hr) | 2005-04-11 | 2012-07-31 | Abbott@Laboratories | Farmaceutske smjese s poboljšanim profilom otapanja za slabo topljive lijekove |
| DE602006019870D1 (de) | 2005-06-08 | 2011-03-10 | Rib X Pharmaceuticals Inc | Verfahren zur synthese von triazolen |
| US8470985B2 (en) | 2005-08-24 | 2013-06-25 | Rib-X Pharmaceuticals, Inc. | Triazole compounds and methods of making and using the same |
| DK1934238T3 (en) | 2005-08-24 | 2017-09-18 | Melinta Therapeutics Inc | TRIAZOL COMPOUNDS AND METHODS FOR THE PREPARATION AND USE OF THESE |
| WO2011139832A2 (en) * | 2010-04-28 | 2011-11-10 | Rib-X Pharmaceuticals, Inc. | Method for treating mycobacterial infections |
-
2015
- 2015-11-16 JP JP2017525909A patent/JP2017534654A/ja not_active Withdrawn
- 2015-11-16 CN CN201580073501.5A patent/CN107205989A/zh not_active Withdrawn
- 2015-11-16 CR CR20170196A patent/CR20170196A/es unknown
- 2015-11-16 HK HK18103723.8A patent/HK1244211A1/zh unknown
- 2015-11-16 WO PCT/US2015/060851 patent/WO2016077818A1/en not_active Ceased
- 2015-11-16 SG SG11201703856VA patent/SG11201703856VA/en unknown
- 2015-11-16 UY UY0001036402A patent/UY36402A/es not_active Application Discontinuation
- 2015-11-16 AR ARP150103729A patent/AR102666A1/es unknown
- 2015-11-16 EP EP15858675.0A patent/EP3217974A4/en active Pending
- 2015-11-16 EA EA201791051A patent/EA201791051A1/ru unknown
- 2015-11-16 BR BR112017009989-6A patent/BR112017009989A2/pt not_active Application Discontinuation
- 2015-11-16 KR KR1020177015770A patent/KR20170084200A/ko not_active Withdrawn
- 2015-11-16 MX MX2017006319A patent/MX389005B/es unknown
- 2015-11-16 AU AU2015346023A patent/AU2015346023A1/en not_active Abandoned
- 2015-11-16 US US14/942,021 patent/US10471046B2/en active Active
- 2015-11-16 CA CA2967825A patent/CA2967825A1/en active Pending
-
2017
- 2017-05-10 IL IL252197A patent/IL252197A0/en unknown
- 2017-05-12 NI NI201700057A patent/NI201700057A/es unknown
- 2017-05-12 PH PH12017500887A patent/PH12017500887A1/en unknown
- 2017-05-15 CL CL2017001245A patent/CL2017001245A1/es unknown
- 2017-05-15 SV SV2017005444A patent/SV2017005444A/es unknown
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