NO20092547L - Antibakterielle kinolin-derivater - Google Patents
Antibakterielle kinolin-derivaterInfo
- Publication number
- NO20092547L NO20092547L NO20092547A NO20092547A NO20092547L NO 20092547 L NO20092547 L NO 20092547L NO 20092547 A NO20092547 A NO 20092547A NO 20092547 A NO20092547 A NO 20092547A NO 20092547 L NO20092547 L NO 20092547L
- Authority
- NO
- Norway
- Prior art keywords
- quinoline derivatives
- pharmaceutically acceptable
- treatment
- bacterial infection
- compounds
- Prior art date
Links
- 229940027991 antiseptic and disinfectant quinoline derivative Drugs 0.000 title abstract 2
- 125000002943 quinolinyl group Chemical class N1=C(C=CC2=CC=CC=C12)* 0.000 title abstract 2
- 230000000844 anti-bacterial effect Effects 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- 208000035143 Bacterial infection Diseases 0.000 abstract 2
- 208000022362 bacterial infectious disease Diseases 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 150000001204 N-oxides Chemical class 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000012453 solvate Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/12—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D215/14—Radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A61P31/06—Antibacterial agents for tuberculosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A61P31/08—Antibacterial agents for leprosy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Quinoline Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Den foreliggende oppfinnelsen angår nye substituerte kinolinderivater ifølge den generelle formel (Ia) eller formel (Ib): inkludert enhver stereokjemisk isomerform derav, et N-oksid derav, et farmasøytisk akseptabelt salt derav eller et solvat derav. De krevde forbindelsene er nyttige i behandlingen av en bakteriell infeksjon. Også krevet er en sammensetning omfattende en farmasøytisk akseptabel bærer og, som aktiv ingrediens, en terapeutisk effektiv mengde av de krevde forbindelsene, anvendelsen av de krevde forbindelsene eller sammensetninger for fremstillingen av et medikament for behandlingen av en bakteriell infeksjon og en fremgangsmåte for å fremstille de krevde forbindelsene.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP06125529 | 2006-12-06 | ||
| PCT/EP2007/063316 WO2008068270A1 (en) | 2006-12-06 | 2007-12-04 | Antibacterial quinoline derivatives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO20092547L true NO20092547L (no) | 2009-08-24 |
| NO342774B1 NO342774B1 (no) | 2018-08-06 |
Family
ID=38124123
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20092547A NO342774B1 (no) | 2006-12-06 | 2009-07-06 | Antibakterielle kinolin-derivater |
Country Status (29)
| Country | Link |
|---|---|
| US (1) | US20110166179A1 (no) |
| EP (1) | EP2099759B1 (no) |
| JP (1) | JP5356246B2 (no) |
| KR (1) | KR101526175B1 (no) |
| CN (1) | CN101553471B (no) |
| AR (1) | AR064152A1 (no) |
| AT (1) | ATE509915T1 (no) |
| AU (1) | AU2007328890B2 (no) |
| BR (1) | BRPI0720133A2 (no) |
| CA (1) | CA2669829C (no) |
| CL (1) | CL2007003517A1 (no) |
| CY (1) | CY1112230T1 (no) |
| DK (1) | DK2099759T3 (no) |
| ES (1) | ES2366062T3 (no) |
| HK (1) | HK1137431A1 (no) |
| HR (1) | HRP20110540T1 (no) |
| IL (1) | IL199084A0 (no) |
| JO (1) | JO2725B1 (no) |
| ME (1) | ME01245B (no) |
| MX (1) | MX2009005981A (no) |
| NO (1) | NO342774B1 (no) |
| NZ (1) | NZ577069A (no) |
| PL (1) | PL2099759T3 (no) |
| PT (1) | PT2099759E (no) |
| RS (1) | RS51848B (no) |
| RU (1) | RU2439058C2 (no) |
| SI (1) | SI2099759T1 (no) |
| TW (1) | TWI487525B (no) |
| WO (1) | WO2008068270A1 (no) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2786089C (en) * | 2010-01-04 | 2014-04-15 | Nippon Soda Co., Ltd. | Nitrogen-containing heterocyclic compound and agricultural fungicide |
| AR086411A1 (es) | 2011-05-20 | 2013-12-11 | Nippon Soda Co | Compuesto heterociclico conteniendo nitrogeno y fungicida para el uso en agricultura y jardineria |
| RU2486175C2 (ru) * | 2011-09-12 | 2013-06-27 | Закрытое Акционерное Общество "Фарм-Синтез" | Производные хинолина, в частности 5,6,7-замещенные 1-(2-хлорхинолин-3-ил)-4-диметиламино-2-(нафталин-1-ил)-1-фенилбутан-2-олы, способ получения и применение соединений |
| EA038350B1 (ru) * | 2012-04-27 | 2021-08-12 | Янссен Фармацевтика Нв | Антибактериальные хинолиновые производные |
| ES2576491T3 (es) * | 2012-04-27 | 2016-07-07 | Janssen Pharmaceutica, N.V. | Derivados de quinolina antibacterianos |
| CN105232540A (zh) * | 2015-09-29 | 2016-01-13 | 王洪燕 | 一种治疗烧伤后感染的药物组合物 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL222801B1 (pl) * | 2002-07-25 | 2016-09-30 | Janssen Pharmaceutica Nv | Pochodne chinoliny, ich zastosowanie, sposób ich wytwarzania oraz kompozycja farmaceutyczna zawierająca je |
| PT1711181E (pt) * | 2004-01-23 | 2009-12-29 | Janssen Pharmaceutica Nv | Derivados quinolina e sua utilização como inibidores micobacterianos |
| EP1753427B1 (en) * | 2004-05-28 | 2008-04-02 | Janssen Pharmaceutica N.V. | Use of substituted quinoline derivatives for the treatment of drug resistant mycobacterial diseases |
| EE05394B1 (et) * | 2004-12-24 | 2011-04-15 | Janssen Pharmaceutica N.V. | Kinoliinihendid kasutamiseks latentse tuberkuloosi ravis |
-
2007
- 2007-11-29 JO JO2007506A patent/JO2725B1/en active
- 2007-12-04 US US12/516,396 patent/US20110166179A1/en not_active Abandoned
- 2007-12-04 CA CA2669829A patent/CA2669829C/en active Active
- 2007-12-04 JP JP2009539741A patent/JP5356246B2/ja not_active Expired - Fee Related
- 2007-12-04 PL PL07847814T patent/PL2099759T3/pl unknown
- 2007-12-04 AU AU2007328890A patent/AU2007328890B2/en not_active Ceased
- 2007-12-04 EP EP07847814A patent/EP2099759B1/en active Active
- 2007-12-04 BR BRPI0720133-8A patent/BRPI0720133A2/pt not_active Application Discontinuation
- 2007-12-04 RS RS20110354A patent/RS51848B/en unknown
- 2007-12-04 WO PCT/EP2007/063316 patent/WO2008068270A1/en active Application Filing
- 2007-12-04 SI SI200730665T patent/SI2099759T1/sl unknown
- 2007-12-04 MX MX2009005981A patent/MX2009005981A/es active IP Right Grant
- 2007-12-04 KR KR1020097013237A patent/KR101526175B1/ko active IP Right Grant
- 2007-12-04 RU RU2009125520/04A patent/RU2439058C2/ru active
- 2007-12-04 DK DK07847814.6T patent/DK2099759T3/da active
- 2007-12-04 ME MEP-2011-141A patent/ME01245B/me unknown
- 2007-12-04 ES ES07847814T patent/ES2366062T3/es active Active
- 2007-12-04 NZ NZ577069A patent/NZ577069A/en unknown
- 2007-12-04 PT PT07847814T patent/PT2099759E/pt unknown
- 2007-12-04 AT AT07847814T patent/ATE509915T1/de active
- 2007-12-04 CN CN2007800454055A patent/CN101553471B/zh active Active
- 2007-12-05 TW TW096146211A patent/TWI487525B/zh active
- 2007-12-05 AR ARP070105445A patent/AR064152A1/es unknown
- 2007-12-05 CL CL200703517A patent/CL2007003517A1/es unknown
-
2009
- 2009-06-02 IL IL199084A patent/IL199084A0/en active IP Right Grant
- 2009-07-06 NO NO20092547A patent/NO342774B1/no unknown
-
2010
- 2010-01-29 HK HK10101065.6A patent/HK1137431A1/xx not_active IP Right Cessation
-
2011
- 2011-07-21 HR HR20110540T patent/HRP20110540T1/hr unknown
- 2011-08-10 CY CY20111100772T patent/CY1112230T1/el unknown
Also Published As
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