CY1112230T1 - Αντιβακτηριακα παραγωγα κινολινης - Google Patents
Αντιβακτηριακα παραγωγα κινολινηςInfo
- Publication number
- CY1112230T1 CY1112230T1 CY20111100772T CY111100772T CY1112230T1 CY 1112230 T1 CY1112230 T1 CY 1112230T1 CY 20111100772 T CY20111100772 T CY 20111100772T CY 111100772 T CY111100772 T CY 111100772T CY 1112230 T1 CY1112230 T1 CY 1112230T1
- Authority
- CY
- Cyprus
- Prior art keywords
- compounds
- kinolin
- producers
- antibacterial
- pharmaceutically acceptable
- Prior art date
Links
- 230000000844 anti-bacterial effect Effects 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 4
- 208000035143 Bacterial infection Diseases 0.000 abstract 2
- 208000022362 bacterial infectious disease Diseases 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 150000001204 N-oxides Chemical class 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 229940027991 antiseptic and disinfectant quinoline derivative Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 125000002943 quinolinyl group Chemical class N1=C(C=CC2=CC=CC=C12)* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000012453 solvate Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/12—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D215/14—Radicals substituted by oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A61P31/06—Antibacterial agents for tuberculosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A61P31/08—Antibacterial agents for leprosy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Quinoline Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Η παρούσα εφεύρεση αναφέρεται σε νέα υποκατεστημένα παράγωγα κινολίνης σύμφωνα με το γενικό Τύπο (Ia) ή το Τύπο (Ib), συμπεριλαμβάνοντας οποιαδήποτε στερεοχημικώς ισομερή μορφή αυτών, ένα Ν-οξείδιο αυτών, ένα φαρμακευτικώς αποδεκτό άλας αυτών ή ένα επιδιαλυτωμένο σύμπλοκο αυτών. Οι ενώσεις που αξιώνονται είναι χρήσιμες στη θεραπευτική αντιμετώπιση μίας βακτηριακής λοίμωξης. Επίσης, αξιώνεται μία σύνθεση που περιλαμβάνει ένα φαρμακευτικώς αποδεκτό φορέα και, ως δραστικό συστατικό, μία θεραπευτικώς αποτελεσματική ποσότητα των ενώσεων που αξιώνονται, η χρήση των ενώσεων που αξιώνονται ή των συνθέσεων για την παρασκευή ενός φαρμάκου για τη θεραπευτική αντιμετώπιση μίας βακτηριακής λοίμωξης και μία διαδικασία για την παρασκευή των ενώσεων που αξιώνονται.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP06125529 | 2006-12-06 | ||
| EP07847814A EP2099759B1 (en) | 2006-12-06 | 2007-12-04 | Antibacterial quinoline derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CY1112230T1 true CY1112230T1 (el) | 2015-12-09 |
Family
ID=38124123
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CY20111100772T CY1112230T1 (el) | 2006-12-06 | 2011-08-10 | Αντιβακτηριακα παραγωγα κινολινης |
Country Status (29)
| Country | Link |
|---|---|
| US (1) | US20110166179A1 (el) |
| EP (1) | EP2099759B1 (el) |
| JP (1) | JP5356246B2 (el) |
| KR (1) | KR101526175B1 (el) |
| CN (1) | CN101553471B (el) |
| AR (1) | AR064152A1 (el) |
| AT (1) | ATE509915T1 (el) |
| AU (1) | AU2007328890B2 (el) |
| BR (1) | BRPI0720133A2 (el) |
| CA (1) | CA2669829C (el) |
| CL (1) | CL2007003517A1 (el) |
| CY (1) | CY1112230T1 (el) |
| DK (1) | DK2099759T3 (el) |
| ES (1) | ES2366062T3 (el) |
| HK (1) | HK1137431A1 (el) |
| HR (1) | HRP20110540T1 (el) |
| IL (1) | IL199084A0 (el) |
| JO (1) | JO2725B1 (el) |
| ME (1) | ME01245B (el) |
| MX (1) | MX2009005981A (el) |
| NO (1) | NO342774B1 (el) |
| NZ (1) | NZ577069A (el) |
| PL (1) | PL2099759T3 (el) |
| PT (1) | PT2099759E (el) |
| RS (1) | RS51848B (el) |
| RU (1) | RU2439058C2 (el) |
| SI (1) | SI2099759T1 (el) |
| TW (1) | TWI487525B (el) |
| WO (1) | WO2008068270A1 (el) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SI2522658T1 (sl) * | 2010-01-04 | 2018-12-31 | Nippon Soda Co., Ltd. | Dušik-vsebujoča heterociklična spojina in kmetijski/hortikulturni germicid |
| AR086411A1 (es) | 2011-05-20 | 2013-12-11 | Nippon Soda Co | Compuesto heterociclico conteniendo nitrogeno y fungicida para el uso en agricultura y jardineria |
| RU2486175C2 (ru) * | 2011-09-12 | 2013-06-27 | Закрытое Акционерное Общество "Фарм-Синтез" | Производные хинолина, в частности 5,6,7-замещенные 1-(2-хлорхинолин-3-ил)-4-диметиламино-2-(нафталин-1-ил)-1-фенилбутан-2-олы, способ получения и применение соединений |
| CN104254527B (zh) * | 2012-04-27 | 2017-05-31 | 詹森药业有限公司 | 抗菌的喹啉衍生物 |
| AU2013254670B2 (en) * | 2012-04-27 | 2017-03-30 | Janssen Pharmaceutica Nv | Antibacterial quinoline derivatives |
| CN106806367A (zh) * | 2015-09-29 | 2017-06-09 | 王洪燕 | 一种治疗烧伤后感染的药物组合物 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT2301544E (pt) * | 2002-07-25 | 2012-12-10 | Janssen Pharmaceutica Nv | Novos inibidores de micobactérias |
| RS51074B (sr) * | 2004-01-23 | 2010-10-31 | Janssen Pharmaceutica N.V. | Derivati kvinolina i njihova upotreba kao mikobakterijskih inhibitora |
| DK1753427T3 (da) * | 2004-05-28 | 2008-07-21 | Janssen Pharmaceutica Nv | Anvendelse af substituerede quinolinderivater til behandling af lægemiddelresistente mykobakteriesygdomme |
| EE05394B1 (et) * | 2004-12-24 | 2011-04-15 | Janssen Pharmaceutica N.V. | Kinoliinihendid kasutamiseks latentse tuberkuloosi ravis |
-
2007
- 2007-11-29 JO JO2007506A patent/JO2725B1/en active
- 2007-12-04 SI SI200730665T patent/SI2099759T1/sl unknown
- 2007-12-04 DK DK07847814.6T patent/DK2099759T3/da active
- 2007-12-04 EP EP07847814A patent/EP2099759B1/en active Active
- 2007-12-04 PT PT07847814T patent/PT2099759E/pt unknown
- 2007-12-04 MX MX2009005981A patent/MX2009005981A/es active IP Right Grant
- 2007-12-04 RS RS20110354A patent/RS51848B/en unknown
- 2007-12-04 CN CN2007800454055A patent/CN101553471B/zh active Active
- 2007-12-04 WO PCT/EP2007/063316 patent/WO2008068270A1/en active Application Filing
- 2007-12-04 JP JP2009539741A patent/JP5356246B2/ja not_active Expired - Fee Related
- 2007-12-04 NZ NZ577069A patent/NZ577069A/en unknown
- 2007-12-04 AU AU2007328890A patent/AU2007328890B2/en not_active Ceased
- 2007-12-04 AT AT07847814T patent/ATE509915T1/de active
- 2007-12-04 BR BRPI0720133-8A patent/BRPI0720133A2/pt not_active Application Discontinuation
- 2007-12-04 CA CA2669829A patent/CA2669829C/en active Active
- 2007-12-04 RU RU2009125520/04A patent/RU2439058C2/ru active
- 2007-12-04 ES ES07847814T patent/ES2366062T3/es active Active
- 2007-12-04 US US12/516,396 patent/US20110166179A1/en not_active Abandoned
- 2007-12-04 PL PL07847814T patent/PL2099759T3/pl unknown
- 2007-12-04 KR KR1020097013237A patent/KR101526175B1/ko active IP Right Grant
- 2007-12-04 ME MEP-2011-141A patent/ME01245B/me unknown
- 2007-12-05 CL CL200703517A patent/CL2007003517A1/es unknown
- 2007-12-05 TW TW096146211A patent/TWI487525B/zh active
- 2007-12-05 AR ARP070105445A patent/AR064152A1/es unknown
-
2009
- 2009-06-02 IL IL199084A patent/IL199084A0/en active IP Right Grant
- 2009-07-06 NO NO20092547A patent/NO342774B1/no unknown
-
2010
- 2010-01-29 HK HK10101065.6A patent/HK1137431A1/xx not_active IP Right Cessation
-
2011
- 2011-07-21 HR HR20110540T patent/HRP20110540T1/hr unknown
- 2011-08-10 CY CY20111100772T patent/CY1112230T1/el unknown
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