JP2018532382A5 - - Google Patents
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- JP2018532382A5 JP2018532382A5 JP2018511114A JP2018511114A JP2018532382A5 JP 2018532382 A5 JP2018532382 A5 JP 2018532382A5 JP 2018511114 A JP2018511114 A JP 2018511114A JP 2018511114 A JP2018511114 A JP 2018511114A JP 2018532382 A5 JP2018532382 A5 JP 2018532382A5
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- JP
- Japan
- Prior art keywords
- peptide
- cell
- seq
- antigen
- recognizes
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 108090000765 processed proteins & peptides Proteins 0.000 claims 9
- 210000001744 T-lymphocyte Anatomy 0.000 claims 4
- 210000004027 cell Anatomy 0.000 claims 3
- 108091008874 T cell receptors Proteins 0.000 claims 2
- 102000016266 T-Cell Antigen Receptors Human genes 0.000 claims 2
- 239000000427 antigen Substances 0.000 claims 2
- 108091007433 antigens Proteins 0.000 claims 2
- 102000036639 antigens Human genes 0.000 claims 2
- 239000013604 expression vector Substances 0.000 claims 2
- 108020004707 nucleic acids Proteins 0.000 claims 2
- 102000039446 nucleic acids Human genes 0.000 claims 2
- 150000007523 nucleic acids Chemical class 0.000 claims 2
- 108091023037 Aptamer Proteins 0.000 claims 1
- 102000006354 HLA-DR Antigens Human genes 0.000 claims 1
- 108010058597 HLA-DR Antigens Proteins 0.000 claims 1
- 239000004480 active ingredient Substances 0.000 claims 1
- 150000001413 amino acids Chemical class 0.000 claims 1
- 210000000612 antigen-presenting cell Anatomy 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 230000004927 fusion Effects 0.000 claims 1
- 108020001507 fusion proteins Proteins 0.000 claims 1
- 102000037865 fusion proteins Human genes 0.000 claims 1
- 230000005934 immune activation Effects 0.000 claims 1
- 238000000338 in vitro Methods 0.000 claims 1
- 108010028930 invariant chain Proteins 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
- 239000003381 stabilizer Substances 0.000 claims 1
- 239000003053 toxin Substances 0.000 claims 1
- 231100000765 toxin Toxicity 0.000 claims 1
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021072989A JP7506026B2 (ja) | 2015-08-28 | 2021-04-23 | 様々ながんの免疫治療で使用するための新規ペプチド、ペプチドおよびスキャフォールド組み合わせ |
| JP2024095596A JP2024123066A (ja) | 2015-08-28 | 2024-06-13 | 様々ながんの免疫治療で使用するための新規ペプチド、ペプチドおよびスキャフォールド組み合わせ |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562211276P | 2015-08-28 | 2015-08-28 | |
| GBGB1515321.6A GB201515321D0 (en) | 2015-08-28 | 2015-08-28 | Novel peptides, combination of peptides and scaffolds for use in immunotherapeutic treatment of various cancers |
| US62/211,276 | 2015-08-28 | ||
| GB1515321.6 | 2015-08-28 | ||
| PCT/EP2016/070146 WO2017036936A1 (en) | 2015-08-28 | 2016-08-26 | Novel peptides, combination of peptides and scaffolds for use in immunotherapeutic treatment of various cancers |
Related Child Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018142058A Division JP6742370B2 (ja) | 2015-08-28 | 2018-07-30 | 様々ながんの免疫治療で使用するための新規ペプチド、ペプチドおよびスキャフォールド組み合わせ |
| JP2021072989A Division JP7506026B2 (ja) | 2015-08-28 | 2021-04-23 | 様々ながんの免疫治療で使用するための新規ペプチド、ペプチドおよびスキャフォールド組み合わせ |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018532382A JP2018532382A (ja) | 2018-11-08 |
| JP2018532382A5 true JP2018532382A5 (enExample) | 2019-10-03 |
| JP6970974B2 JP6970974B2 (ja) | 2021-11-24 |
Family
ID=54326487
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018511114A Active JP6970974B2 (ja) | 2015-08-28 | 2016-08-26 | 様々ながんの免疫治療で使用するための新規ペプチド、ペプチドおよびスキャフォールド組み合わせ |
| JP2021072989A Active JP7506026B2 (ja) | 2015-08-28 | 2021-04-23 | 様々ながんの免疫治療で使用するための新規ペプチド、ペプチドおよびスキャフォールド組み合わせ |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021072989A Active JP7506026B2 (ja) | 2015-08-28 | 2021-04-23 | 様々ながんの免疫治療で使用するための新規ペプチド、ペプチドおよびスキャフォールド組み合わせ |
Country Status (18)
| Country | Link |
|---|---|
| US (7) | US10576132B2 (enExample) |
| EP (2) | EP3341014A1 (enExample) |
| JP (2) | JP6970974B2 (enExample) |
| KR (3) | KR102515909B1 (enExample) |
| CN (1) | CN107921111B (enExample) |
| AU (3) | AU2016313684B2 (enExample) |
| BR (1) | BR112018003460A2 (enExample) |
| CA (2) | CA2996963A1 (enExample) |
| CR (6) | CR20200495A (enExample) |
| EA (2) | EA201891874A3 (enExample) |
| GB (1) | GB201515321D0 (enExample) |
| MA (7) | MA43457A1 (enExample) |
| MX (1) | MX2018002480A (enExample) |
| PE (2) | PE20181164A1 (enExample) |
| SG (3) | SG10202001830PA (enExample) |
| TW (15) | TWI722661B (enExample) |
| UA (1) | UA124577C2 (enExample) |
| WO (1) | WO2017036936A1 (enExample) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB201507030D0 (en) * | 2015-04-24 | 2015-06-10 | Immatics Biotechnologies Gmbh | Immunotherapy against lung cancers, in particular NSCLC |
| GB201515321D0 (en) * | 2015-08-28 | 2015-10-14 | Immatics Biotechnologies Gmbh | Novel peptides, combination of peptides and scaffolds for use in immunotherapeutic treatment of various cancers |
| CN108601731A (zh) | 2015-12-16 | 2018-09-28 | 磨石肿瘤生物技术公司 | 新抗原的鉴别、制造及使用 |
| GB201609193D0 (en) | 2016-05-25 | 2016-07-06 | Immatics Biotechnologies Gmbh | Novel peptides, combination of peptides as targets for use in immunotherapy against gallbladder cancer and cholangiocarcinoma and other cancers |
| JP7075125B2 (ja) | 2016-05-25 | 2022-05-25 | イマティクス バイオテクノロジーズ ゲーエムベーハー | 標的としてのおよび胆嚢がんおよび胆管がんおよびその他のがんに対する免疫療法で使用するための新規ペプチド、ペプチド組み合わせ |
| EP4317432A3 (en) | 2016-12-08 | 2024-04-17 | Immatics Biotechnologies GmbH | T cell receptors with improved pairing |
| DE102016123893A1 (de) | 2016-12-08 | 2018-06-14 | Immatics Biotechnologies Gmbh | T-Zellrezeptoren mit verbesserter Bindung |
| CN108250286B (zh) * | 2016-12-28 | 2021-06-08 | 香雪生命科学技术（广东）有限公司 | 源自于pasd1的肿瘤抗原短肽 |
| EA201992416A1 (ru) | 2017-04-10 | 2020-02-25 | Имматикс Байотекнолоджиз Гмбх | Пептиды и комбинации пептидов для применения в иммунотерапии лейкозов и других видов рака |
| CN111533799A (zh) * | 2017-04-10 | 2020-08-14 | 伊玛提克斯生物技术有限公司 | 用于白血病和其他癌症免疫治疗的肽和肽组合物 |
| DE102017115966A1 (de) | 2017-07-14 | 2019-01-17 | Immatics Biotechnologies Gmbh | Polypeptidmolekül mit verbesserter zweifacher Spezifität |
| ES2871146T3 (es) | 2017-07-14 | 2021-10-28 | Immatics Biotechnologies Gmbh | Molécula de polipéptido con especificidad dual mejorada |
| PL3688155T3 (pl) * | 2017-09-28 | 2023-09-11 | Immpact-Bio Ltd. | Uniwersalna platforma do wytwarzania hamującego chimerycznego receptora antygenowego (icar) |
| EP4576103A3 (en) | 2017-10-10 | 2025-08-27 | Gritstone bio, Inc. | Neoantigen identification using hotspots |
| EP3714275A4 (en) | 2017-11-22 | 2021-10-27 | Gritstone bio, Inc. | REDUCTION OF JUNCTION EPITOPIC PRESENTATION FOR NEOANTIGENS |
| DE102018107224A1 (de) * | 2018-02-21 | 2019-08-22 | Immatics Biotechnologies Gmbh | Peptide und Kombinationen von Peptiden nicht-kanonischen Ursprungs zur Verwendung in der Immuntherapie gegen verschiedene Krebsarten |
| TW202016131A (zh) * | 2018-05-16 | 2020-05-01 | 德商英麥提克生物技術股份有限公司 | 用於抗癌免疫治療的肽 |
| CN109467596B (zh) * | 2018-11-12 | 2021-11-09 | 湖北省农业科学院畜牧兽医研究所 | 转录因子sp1在调控猪rtl1基因表达中的应用 |
| CN109738929B (zh) * | 2018-12-03 | 2022-10-21 | 中国辐射防护研究院 | 一种基于居民食物最大消费量的剂量估算方法及系统 |
| TWI858016B (zh) * | 2019-02-18 | 2024-10-11 | 日商肽夢想股份有限公司 | 血球凝集素結合肽 |
| WO2020230792A1 (ja) * | 2019-05-13 | 2020-11-19 | 伊東 恭悟 | がん患者のペプチドワクチン療法に対する適格性を判定する方法 |
| CN110123453B (zh) * | 2019-05-31 | 2021-07-23 | 东北大学 | 一种基于无标记增强现实的手术导航系统 |
| US20230158132A1 (en) * | 2020-04-14 | 2023-05-25 | Universite De Montreal | Novel tumor-specific antigens for acute lymphoblastic leukemia (all) and uses thereof |
| CN111910000B (zh) * | 2020-07-02 | 2022-07-01 | 中山大学肿瘤防治中心（中山大学附属肿瘤医院、中山大学肿瘤研究所） | 一种预测鼻咽癌预后的肿瘤微环境成分标志物组合及系统 |
| BR112023021806A2 (pt) * | 2021-04-19 | 2024-01-23 | Univ Texas | Métodos e composições compreendendo peptídeos mhc classe i |
| CN115607573B (zh) * | 2022-12-16 | 2023-05-23 | 北京大学第三医院（北京大学第三临床医学院） | 一种用于调节杀伤性t细胞活性的方法、药物及其应用 |
| WO2025015234A2 (en) * | 2023-07-13 | 2025-01-16 | Ltz Therapeutics Inc. | Multispecific antibodies and uses thereof |
| CN118834328B (zh) * | 2024-07-02 | 2025-09-16 | 江苏海洋大学 | 金属蛋白酶9抗原决定基印迹纳米颗粒的制备方法及应用 |
| CN120183512B (zh) * | 2025-05-23 | 2025-08-12 | 浙江省肿瘤医院 | 基于转录组测序构建的用于诊断早期宫颈癌淋巴结转移的方法、模型 |
| CN120908452B (zh) * | 2025-09-28 | 2025-12-02 | 吉林大学 | 一种用于卵巢癌初步筛查的试剂盒及其应用 |
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| US7342108B2 (en) * | 1998-06-25 | 2008-03-11 | The General Hospital Corporation | De novo DNA cytosine methyltransferase genes, polypeptides and uses thereof |
| JP4315301B2 (ja) | 1998-10-30 | 2009-08-19 | 独立行政法人科学技術振興機構 | ヒトＨ３７タンパク質と、このタンパク質をコードする ｃＤＮＡ |
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2015
- 2015-08-28 GB GBGB1515321.6A patent/GB201515321D0/en not_active Ceased
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2016
- 2016-08-26 JP JP2018511114A patent/JP6970974B2/ja active Active
- 2016-08-26 CR CR20200495A patent/CR20200495A/es unknown
- 2016-08-26 CR CR20200492A patent/CR20200492A/es unknown
- 2016-08-26 MX MX2018002480A patent/MX2018002480A/es unknown
- 2016-08-26 KR KR1020217031080A patent/KR102515909B1/ko active Active
- 2016-08-26 TW TW108141496A patent/TWI722661B/zh not_active IP Right Cessation
- 2016-08-26 CR CR20180423A patent/CR20180423A/es unknown
- 2016-08-26 AU AU2016313684A patent/AU2016313684B2/en not_active Ceased
- 2016-08-26 CA CA2996963A patent/CA2996963A1/en active Pending
- 2016-08-26 WO PCT/EP2016/070146 patent/WO2017036936A1/en not_active Ceased
- 2016-08-26 CR CR20200493A patent/CR20200493A/es unknown
- 2016-08-26 EP EP16762752.0A patent/EP3341014A1/en not_active Withdrawn
- 2016-08-26 EA EA201891874A patent/EA201891874A3/ru unknown
- 2016-08-26 TW TW108141491A patent/TWI722657B/zh not_active IP Right Cessation
- 2016-08-26 MA MA43457A patent/MA43457A1/fr unknown
- 2016-08-26 PE PE2018000318A patent/PE20181164A1/es unknown
- 2016-08-26 UA UAA201808797A patent/UA124577C2/uk unknown
- 2016-08-26 BR BR112018003460-6A patent/BR112018003460A2/pt not_active Application Discontinuation
- 2016-08-26 MA MA43459A patent/MA43459A1/fr unknown
- 2016-08-26 EA EA201890560A patent/EA201890560A1/ru unknown
- 2016-08-26 MA MA43460A patent/MA43460A1/fr unknown
- 2016-08-26 KR KR1020187023153A patent/KR102308798B1/ko active Active
- 2016-08-26 TW TW108141489A patent/TWI722655B/zh not_active IP Right Cessation
- 2016-08-26 SG SG10202001830PA patent/SG10202001830PA/en unknown
- 2016-08-26 TW TW108141490A patent/TWI722656B/zh not_active IP Right Cessation
- 2016-08-26 EP EP18201208.8A patent/EP3461494A1/en active Pending
- 2016-08-26 TW TW107128393A patent/TWI699377B/zh not_active IP Right Cessation
- 2016-08-26 CA CA3072922A patent/CA3072922A1/en active Pending
- 2016-08-26 SG SG10201807588TA patent/SG10201807588TA/en unknown
- 2016-08-26 CR CR20200494A patent/CR20200494A/es unknown
- 2016-08-26 CN CN201680050119.7A patent/CN107921111B/zh active Active
- 2016-08-26 TW TW108141488A patent/TWI722654B/zh not_active IP Right Cessation
- 2016-08-26 TW TW108141487A patent/TWI722653B/zh not_active IP Right Cessation
- 2016-08-26 SG SG10202001831SA patent/SG10202001831SA/en unknown
- 2016-08-26 TW TW108141494A patent/TWI722659B/zh not_active IP Right Cessation
- 2016-08-26 PE PE2018001375A patent/PE20181517A1/es unknown
- 2016-08-26 MA MA43461A patent/MA43461B1/fr unknown
- 2016-08-26 CR CR20180174A patent/CR20180174A/es unknown
- 2016-08-26 TW TW109122012A patent/TWI782290B/zh not_active IP Right Cessation
- 2016-08-26 KR KR1020187007555A patent/KR20180038550A/ko not_active Ceased
- 2016-08-26 TW TW105127400A patent/TW201708246A/zh unknown
- 2016-08-26 TW TW108141495A patent/TWI722660B/zh not_active IP Right Cessation
- 2016-08-26 MA MA045073A patent/MA45073A/fr unknown
- 2016-08-26 TW TW108141498A patent/TWI722663B/zh not_active IP Right Cessation
- 2016-08-26 MA MA43458A patent/MA43458A1/fr unknown
- 2016-08-26 TW TW108141499A patent/TWI722664B/zh not_active IP Right Cessation
- 2016-08-26 MA MA042694A patent/MA42694A/fr unknown
- 2016-08-26 TW TW108141497A patent/TWI722662B/zh not_active IP Right Cessation
- 2016-08-26 TW TW108141492A patent/TWI722658B/zh not_active IP Right Cessation
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2018
- 2018-05-17 US US15/982,293 patent/US10576132B2/en active Active
- 2018-05-17 US US15/982,500 patent/US10525114B2/en active Active
- 2018-10-18 AU AU2018250464A patent/AU2018250464B2/en not_active Ceased
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2019
- 2019-11-04 US US16/673,619 patent/US10695411B2/en active Active
- 2019-11-04 US US16/673,608 patent/US10568950B1/en active Active
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2020
- 2020-03-16 AU AU2020201896A patent/AU2020201896B2/en not_active Ceased
- 2020-05-29 US US16/887,765 patent/US10898557B2/en not_active Expired - Fee Related
- 2020-06-29 US US16/915,420 patent/US10898558B2/en not_active Expired - Fee Related
- 2020-09-10 US US17/017,358 patent/US11065316B2/en active Active
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2021
- 2021-04-23 JP JP2021072989A patent/JP7506026B2/ja active Active