JP2016508143A5 - - Google Patents
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- Publication number
- JP2016508143A5 JP2016508143A5 JP2015551157A JP2015551157A JP2016508143A5 JP 2016508143 A5 JP2016508143 A5 JP 2016508143A5 JP 2015551157 A JP2015551157 A JP 2015551157A JP 2015551157 A JP2015551157 A JP 2015551157A JP 2016508143 A5 JP2016508143 A5 JP 2016508143A5
- Authority
- JP
- Japan
- Prior art keywords
- fusion protein
- polypeptide
- amino acid
- seq
- pharmaceutically
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 108090000765 processed proteins & peptides Proteins 0.000 claims 13
- 102000037865 fusion proteins Human genes 0.000 claims 10
- 108020001507 fusion proteins Proteins 0.000 claims 10
- 229920001184 polypeptide Polymers 0.000 claims 9
- 102000004196 processed proteins & peptides Human genes 0.000 claims 9
- 125000003275 alpha amino acid group Chemical group 0.000 claims 6
- 102000004169 proteins and genes Human genes 0.000 claims 4
- 108090000623 proteins and genes Proteins 0.000 claims 4
- 102000039446 nucleic acids Human genes 0.000 claims 3
- 108020004707 nucleic acids Proteins 0.000 claims 3
- 150000007523 nucleic acids Chemical class 0.000 claims 3
- 210000004027 cell Anatomy 0.000 claims 2
- 239000003795 chemical substances by application Substances 0.000 claims 2
- 102000019034 Chemokines Human genes 0.000 claims 1
- 108010012236 Chemokines Proteins 0.000 claims 1
- 102000004127 Cytokines Human genes 0.000 claims 1
- 108090000695 Cytokines Proteins 0.000 claims 1
- 102000008100 Human Serum Albumin Human genes 0.000 claims 1
- 108091006905 Human Serum Albumin Proteins 0.000 claims 1
- 102000014150 Interferons Human genes 0.000 claims 1
- 108010050904 Interferons Proteins 0.000 claims 1
- 102000007056 Recombinant Fusion Proteins Human genes 0.000 claims 1
- 108010008281 Recombinant Fusion Proteins Proteins 0.000 claims 1
- 210000001744 T-lymphocyte Anatomy 0.000 claims 1
- 239000003146 anticoagulant agent Substances 0.000 claims 1
- 229940127219 anticoagulant drug Drugs 0.000 claims 1
- 210000004369 blood Anatomy 0.000 claims 1
- 239000008280 blood Substances 0.000 claims 1
- 229960000182 blood factors Drugs 0.000 claims 1
- 238000012258 culturing Methods 0.000 claims 1
- 230000009977 dual effect Effects 0.000 claims 1
- 239000005556 hormone Substances 0.000 claims 1
- 229940088597 hormone Drugs 0.000 claims 1
- 229940079322 interferon Drugs 0.000 claims 1
- 230000002934 lysing effect Effects 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- 210000002966 serum Anatomy 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP13150171.0 | 2013-01-03 | ||
| EP13150171.0A EP2752426A1 (en) | 2013-01-03 | 2013-01-03 | Human serum albumin binding compounds and fusion proteins thereof |
| PCT/EP2013/077227 WO2014106583A1 (en) | 2013-01-03 | 2013-12-18 | Human serum albumin binding compounds and fusion proteins thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2016508143A JP2016508143A (ja) | 2016-03-17 |
| JP2016508143A5 true JP2016508143A5 (enExample) | 2017-01-12 |
Family
ID=47458817
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015551157A Pending JP2016508143A (ja) | 2013-01-03 | 2013-12-18 | ヒト血清アルブミン結合化合物およびその融合タンパク質 |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US9790475B2 (enExample) |
| EP (2) | EP2752426A1 (enExample) |
| JP (1) | JP2016508143A (enExample) |
| AU (1) | AU2013372004B2 (enExample) |
| CA (1) | CA2896962A1 (enExample) |
| HK (1) | HK1215441A1 (enExample) |
| WO (1) | WO2014106583A1 (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20160060660A (ko) | 2013-10-01 | 2016-05-30 | 글락소스미스클라인 인털렉츄얼 프로퍼티 디벨로프먼트 리미티드 | 친화성 크로마토그래피를 위한 및 치료제의 반감기를 연장시키기 위한 화합물 |
| US20200087390A1 (en) | 2016-12-21 | 2020-03-19 | Amgen Inc. | Anti-tnf alpha antibody formulations |
| AU2018220516B2 (en) | 2017-02-16 | 2025-03-06 | Sonnet BioTherapeutics, Inc. | Albumin binding domain fusion proteins |
| CN107353346A (zh) * | 2017-08-09 | 2017-11-17 | 芜湖英特菲尔生物制品产业研究院有限公司 | 一种由猪白蛋白与猪干扰素γ组成的融合蛋白及其制备方法和一种重组猪长效干扰素γ |
| JP2022521428A (ja) | 2019-02-25 | 2022-04-07 | ザ・ユニバーシティ・オブ・シカゴ | 抗炎症剤に連結されたｅｃｍ親和性ペプチドを用いて炎症性状態および自己免疫状態を処置するための方法および組成物 |
| US20230190881A1 (en) | 2020-02-17 | 2023-06-22 | Biotest Ag | Subcutaneous administration of factor viii |
| CN115698063A (zh) * | 2020-03-06 | 2023-02-03 | 匹兹堡大学联邦高等教育系统 | 血清白蛋白结合纳米抗体组合物以及其使用方法 |
| CN114075279B (zh) * | 2020-08-14 | 2023-05-05 | 上海洛启生物医药技术有限公司 | 非pH依赖性长效型抗血清白蛋白纳米抗体及其应用 |
| US12134635B1 (en) | 2023-12-29 | 2024-11-05 | Sonnet BioTherapeutics, Inc. | Interleukin 18 (IL-18) variants and fusion proteins comprising same |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8607679D0 (en) | 1986-03-27 | 1986-04-30 | Winter G P | Recombinant dna product |
| US4946778A (en) | 1987-09-21 | 1990-08-07 | Genex Corporation | Single polypeptide chain binding molecules |
| IL162181A (en) | 1988-12-28 | 2006-04-10 | Pdl Biopharma Inc | A method of producing humanized immunoglubulin, and polynucleotides encoding the same |
| SE509359C2 (sv) | 1989-08-01 | 1999-01-18 | Cemu Bioteknik Ab | Användning av stabiliserade protein- eller peptidkonjugat för framställning av ett läkemedel |
| US6080560A (en) | 1994-07-25 | 2000-06-27 | Monsanto Company | Method for producing antibodies in plant cells |
| DE60030323T2 (de) | 1999-12-24 | 2007-10-11 | Genentech, Inc., South San Francisco | Verfahren und verbindungen zur verlängerung der halbwertzeiten bei der ausscheidung von biowirksamen verbindungen |
| WO2002076489A1 (en) | 2001-03-09 | 2002-10-03 | Dyax Corp. | Serum albumin binding moieties |
| NZ540194A (en) | 2002-11-08 | 2008-07-31 | Ablynx Nv | Single domain antibodies directed against tumour necrosis factor-alpha and uses therefor |
| EP1892248A1 (en) * | 2006-08-21 | 2008-02-27 | Eidgenössische Technische Hochschule Zürich | Specific and high affinity binding proteins comprising modified SH3 domains of FYN kinase |
| EP2524927A1 (en) * | 2011-05-20 | 2012-11-21 | Covagen AG | New chymase binding compounds and medical uses thereof |
| AU2013231488B2 (en) * | 2012-03-16 | 2017-12-07 | Covagen Ag | Novel binding molecules with antitumoral activity |
-
2013
- 2013-01-03 EP EP13150171.0A patent/EP2752426A1/en not_active Withdrawn
- 2013-12-18 WO PCT/EP2013/077227 patent/WO2014106583A1/en not_active Ceased
- 2013-12-18 JP JP2015551157A patent/JP2016508143A/ja active Pending
- 2013-12-18 EP EP13821463.0A patent/EP2941439B1/en not_active Not-in-force
- 2013-12-18 HK HK16103286.9A patent/HK1215441A1/zh unknown
- 2013-12-18 US US14/758,339 patent/US9790475B2/en not_active Expired - Fee Related
- 2013-12-18 CA CA2896962A patent/CA2896962A1/en not_active Abandoned
- 2013-12-18 AU AU2013372004A patent/AU2013372004B2/en not_active Ceased
-
2017
- 2017-09-25 US US15/714,444 patent/US10364419B2/en not_active Expired - Fee Related
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