|
IN2014DN10515A
(enExample)
|
2006-03-31 |
2015-08-21 |
Chugai Pharmaceutical Co Ltd |
|
|
MX336725B
(es)
|
2007-09-26 |
2016-01-28 |
Chugai Pharmaceutical Co Ltd |
Metodo de modificacion del punto isoelectrico de anticuerpos medinate la sustitucion de aminoacidos en region de determinacion de complementariedad (cdr).
|
|
TWI700293B
(zh)
|
2008-04-11 |
2020-08-01 |
日商中外製藥股份有限公司 |
重複結合複數個抗原的抗體
|
|
KR102568454B1
(ko)
|
2010-11-30 |
2023-08-18 |
추가이 세이야쿠 가부시키가이샤 |
복수 분자의 항원에 반복해서 결합하는 항원 결합 분자
|
|
GB201203442D0
(en)
|
2012-02-28 |
2012-04-11 |
Univ Birmingham |
Immunotherapeutic molecules and uses
|
|
MX2014013041A
(es)
|
2012-04-27 |
2015-03-19 |
Cytomx Therapeutics Inc |
Anticuerpos activables que se ligan al receptor del factor de crecimiento epidermico y metodos de uso de los mismos.
|
|
US20150203591A1
(en)
*
|
2012-08-02 |
2015-07-23 |
Regeneron Pharmaceuticals, Inc. |
Mutivalent antigen-binding proteins
|
|
TWI855488B
(zh)
|
2012-08-24 |
2024-09-11 |
日商中外製藥股份有限公司 |
FcγRIIb特異性Fc區域變異體
|
|
EP3597747B1
(en)
|
2012-08-24 |
2023-03-15 |
Chugai Seiyaku Kabushiki Kaisha |
Mouse fcgammarii-specific fc antibody
|
|
AU2014250434B2
(en)
|
2013-04-02 |
2019-08-08 |
Chugai Seiyaku Kabushiki Kaisha |
Fc region variant
|
|
CN105377297B
(zh)
|
2013-05-28 |
2019-09-17 |
Dcb-美国有限责任公司 |
用于蛋白质药物失活的抗体锁扣
|
|
DK3406633T3
(da)
|
2013-07-25 |
2022-03-28 |
Cytomx Therapeutics Inc |
Multispecifikke antistoffer, multispecifikke aktiverbare antistoffer og fremgangsmåder til anvendelse heraf
|
|
CN104342453A
(zh)
*
|
2013-08-06 |
2015-02-11 |
深圳先进技术研究院 |
含基因工程抗体基因表达盒的微环dna重组母质粒、含该表达盒的微环dna及应用
|
|
US9540440B2
(en)
|
2013-10-30 |
2017-01-10 |
Cytomx Therapeutics, Inc. |
Activatable antibodies that bind epidermal growth factor receptor and methods of use thereof
|
|
US9737623B2
(en)
|
2013-12-11 |
2017-08-22 |
Cytomx Therapeutics, Inc. |
Antibodies that bind activatable antibodies and methods of use thereof
|
|
KR102225489B1
(ko)
|
2013-12-17 |
2021-03-10 |
제넨테크, 인크. |
항-cd3 항체 및 이의 사용 방법
|
|
EP3483593B1
(en)
*
|
2014-03-26 |
2021-04-28 |
Siemens Healthcare Diagnostics Inc. |
Luminescent oxygen channeling immunoassay utilizing three antibodies and methods of production and use thereof
|
|
EP3148581B1
(en)
|
2014-05-30 |
2019-10-09 |
Henlius Biotech Co., Ltd. |
Anti-epidermal growth factor receptor (egfr) antibodies
|
|
AU2015292406B2
(en)
|
2014-07-25 |
2021-03-11 |
Cytomx Therapeutics, Inc |
Anti-CD3 antibodies, activatable anti-CD3 antibodies, multispecific anti-CD3 antibodies, multispecific activatable anti-CD3 antibodies, and methods of using the same
|
|
JP6871155B2
(ja)
*
|
2014-07-25 |
2021-05-12 |
メモリアル スローン ケタリング キャンサー センター |
二重特異性ｈｅｒ２及びｃｄ３結合分子
|
|
US11820832B2
(en)
*
|
2014-07-25 |
2023-11-21 |
Memorial Sloan Kettering Cancer Center |
Bispecific HER2 and CD3 binding molecules
|
|
RS61010B1
(sr)
|
2014-11-20 |
2020-11-30 |
Hoffmann La Roche |
Bispecifični antigen vezujući molekuli koji aktiviraju t ćelije protiv folr1 i cd3
|
|
BR112017010513A2
(pt)
|
2014-11-20 |
2018-04-03 |
F. Hoffmann-La Roche Ag |
?cadeias leves comuns e métodos de uso?
|
|
TWI656133B
(zh)
|
2014-12-19 |
2019-04-11 |
日商中外製藥股份有限公司 |
抗肌抑素之抗體、含變異Ｆｃ區域之多胜肽及使用方法
|
|
IL253180B2
(en)
*
|
2015-01-02 |
2023-04-01 |
Dyax Corp |
Bispecific antibodies against plasma kallikrein and factor xii
|
|
US20180318417A1
(en)
*
|
2015-01-14 |
2018-11-08 |
Compass Therapeutics Llc |
Multispecific immunomodulatory antigen-binding constructs
|
|
WO2016125495A1
(en)
|
2015-02-05 |
2016-08-11 |
Chugai Seiyaku Kabushiki Kaisha |
Antibodies comprising an ion concentration dependent antigen-binding domain, fc region variants, il-8-binding antibodies, and uses therof
|
|
AU2016233495B2
(en)
*
|
2015-03-13 |
2022-02-24 |
Cytomx Therapeutics, Inc |
Anti-PDL1 antibodies, activatable anti-PDL1 antibodies, and methods of use thereof
|
|
TWI726879B
(zh)
*
|
2015-05-04 |
2021-05-11 |
美商Ｃｙｔｏｍｘ生物製藥公司 |
抗ｃｄ７１抗體類、可活化之抗ｃｄ７１抗體類及使用彼等之方法
|
|
SG10202110908WA
(en)
*
|
2015-05-04 |
2021-11-29 |
Cytomx Therapeutics Inc |
Anti-cd166 antibodies, activatable anti-cd166 antibodies, and methods of use thereof
|
|
EP3296395B2
(en)
|
2015-05-13 |
2024-06-19 |
Chugai Seiyaku Kabushiki Kaisha |
Multiple antigen binding molecular fusion, pharmaceutical composition, method for identifying linear epitope, and method for preparing multiple antigen binding molecular fusion
|
|
US9994638B2
(en)
*
|
2015-05-20 |
2018-06-12 |
Immunwork Inc. |
Peptide core-based multi-arm linkers for treating infectious diseases
|
|
ES2889906T3
(es)
|
2015-05-21 |
2022-01-14 |
Harpoon Therapeutics Inc |
Proteínas de unión triespecíficas y usos médicos
|
|
EP3916018A1
(en)
|
2015-06-16 |
2021-12-01 |
Genentech, Inc. |
Anti-cd3 antibodies and methods of use
|
|
KR102794955B1
(ko)
|
2015-07-21 |
2025-04-15 |
다케다 파머수티컬 컴패니 리미티드 |
Xiia 인자의 단일클론 항체 저해제
|
|
WO2017019729A1
(en)
*
|
2015-07-27 |
2017-02-02 |
The General Hospital Corporation |
Antibody derivatives with conditionally enabled effector function
|
|
JP6548052B2
(ja)
*
|
2015-08-11 |
2019-07-24 |
国立大学法人大阪大学 |
抗体
|
|
IL319047A
(en)
|
2015-08-28 |
2025-04-01 |
Amunix Operating Inc |
Chimeric polypeptide composition and methods for its preparation and use
|
|
EA039736B1
(ru)
*
|
2015-09-15 |
2022-03-04 |
Сайтомкс Терапьютикс, Инк. |
Анти-pdl1-антитела, активируемые анти-pdl1-антитела и способы их применения
|
|
WO2017046301A1
(en)
|
2015-09-18 |
2017-03-23 |
Nestec S.A. |
Savoury concentrates with a flowable texture based on two starches
|
|
MA43017A
(fr)
|
2015-10-02 |
2018-08-08 |
Hoffmann La Roche |
Anticorps bispécifiques spécifiques d'un récepteur de co-stimulation du tnf
|
|
ES2908470T3
(es)
|
2015-11-09 |
2022-04-29 |
Scherer Technologies Llc R P |
Conjugados de anticuerpo anti-CD22-maitansina y métodos de uso de los mismos
|
|
PT3377103T
(pt)
|
2015-11-19 |
2021-05-26 |
Revitope Ltd |
Complementação de fragmento de anticorpo funcional para um sistema de dois componentes para exterminação redirecionada de células indesejadas
|
|
US10533157B1
(en)
|
2015-12-03 |
2020-01-14 |
Nantbio, Inc. |
Recombinant NK cells expressing co-stimulatory molecules
|
|
WO2017110981A1
(en)
|
2015-12-25 |
2017-06-29 |
Chugai Seiyaku Kabushiki Kaisha |
Anti-myostatin antibodies and methods of use
|
|
RU2766000C2
(ru)
|
2016-01-08 |
2022-02-07 |
АльтруБио Инк. |
Четырехвалентные антитела к psgl-1 и их применения
|
|
EP3192810A1
(en)
*
|
2016-01-14 |
2017-07-19 |
Deutsches Krebsforschungszentrum |
Psma binding antibody and uses thereof
|
|
US12128102B2
(en)
|
2016-03-08 |
2024-10-29 |
Takeda Pharmaceutical Company Limited |
Constrained conditionally activated binding proteins
|
|
PL3433280T3
(pl)
*
|
2016-03-22 |
2023-07-31 |
F. Hoffmann-La Roche Ag |
Dwuswoiste cząsteczki limfocytów T aktywowane przez proteazy
|
|
SG11201808085WA
(en)
*
|
2016-03-22 |
2018-10-30 |
Hoffmann La Roche |
Protease-activated t cell bispecific molecules
|
|
CA3024723A1
(en)
|
2016-05-20 |
2017-11-23 |
Robert B. Dubridge |
Single domain serum albumin binding protein
|
|
PT3461261T
(pt)
|
2016-05-20 |
2025-07-31 |
Harpoon Therapeutics Inc |
Proteínas de ligação ao cd3 de fragmento variável de cadeia única
|
|
US11623958B2
(en)
|
2016-05-20 |
2023-04-11 |
Harpoon Therapeutics, Inc. |
Single chain variable fragment CD3 binding proteins
|
|
US11617799B2
(en)
|
2016-06-27 |
2023-04-04 |
Tagworks Pharmaceuticals B.V. |
Cleavable tetrazine used in bio-orthogonal drug activation
|
|
CN109689099B
(zh)
|
2016-08-05 |
2023-02-28 |
中外制药株式会社 |
用于预防或治疗il-8相关疾病的组合物
|
|
IL265046B2
(en)
*
|
2016-08-30 |
2025-04-01 |
Xencor Inc |
Bispecific immunomodulatory antibodies that bind to costimulatory and checkpoint receptors
|
|
CN106632681B
(zh)
*
|
2016-10-11 |
2017-11-14 |
北京东方百泰生物科技有限公司 |
抗egfr和抗cd3双特异抗体及其应用
|
|
WO2018075807A1
(en)
*
|
2016-10-19 |
2018-04-26 |
California Institute For Biomedical Research |
Chimeric antigen receptor effector cell switches with humanized targeting moieties and/or optimized chimeric antigen receptor interacting domains and uses thereof
|
|
EP3538152A4
(en)
*
|
2016-11-09 |
2020-09-30 |
Agenus Inc. |
ANTI-OX40 ANTIBODIES, ANTI-GITR ANTIBODIES, AND PROCESSES FOR USE
|
|
US11466094B2
(en)
|
2016-11-15 |
2022-10-11 |
Genentech, Inc. |
Dosing for treatment with anti-CD20/anti-CD3 bispecific antibodies
|
|
EP3544997A4
(en)
|
2016-11-23 |
2020-07-01 |
Harpoon Therapeutics, Inc. |
PROSTATE SPECIFIC MEMBRANE ANTIGEN BINDING PROTEIN
|
|
KR20190087539A
(ko)
|
2016-11-23 |
2019-07-24 |
하푼 테라퓨틱스, 인크. |
Psma 표적화 삼중특이성 단백질 및 사용 방법
|
|
NZ753324A
(en)
|
2016-12-09 |
2022-02-25 |
Seagen Inc |
Bivalent antibodies masked by coiled coils
|
|
JP7141407B2
(ja)
*
|
2016-12-13 |
2022-09-22 |
エフ．ホフマン－ラ ロシュ アーゲー |
腫瘍試料における標的抗原の存在を決定する方法
|
|
CN108264561B
(zh)
*
|
2016-12-30 |
2021-09-10 |
惠和生物技术(上海)有限公司 |
一种结合cd19、cd3和t细胞负共刺激分子的三功能分子及其应用
|
|
US11046768B2
(en)
|
2017-01-27 |
2021-06-29 |
Memorial Sloan Kettering Cancer Center |
Bispecific HER2 and CD3 binding molecules
|
|
EP4491234A3
(en)
|
2017-02-08 |
2025-04-09 |
Dragonfly Therapeutics, Inc. |
Multi-specific binding proteins for activation of natural killer cells and therapeutic uses thereof to treat cancer
|
|
BR112019017197A2
(pt)
|
2017-02-20 |
2020-04-14 |
Dragonfly Therapeutics, Inc. |
proteínas que se ligam a her2, nkg2d e cd16
|
|
WO2018157147A1
(en)
*
|
2017-02-27 |
2018-08-30 |
Dragonfly Therapeutics, Inc. |
Multispecific binding proteins targeting caix, ano1, mesothelin,trop2, cea, or claudin-18.2
|
|
US11535668B2
(en)
|
2017-02-28 |
2022-12-27 |
Harpoon Therapeutics, Inc. |
Inducible monovalent antigen binding protein
|
|
WO2018178076A1
(en)
|
2017-03-29 |
2018-10-04 |
F. Hoffmann-La Roche Ag |
Bispecific antigen binding molecule for a costimulatory tnf receptor
|
|
WO2018177371A1
(en)
*
|
2017-03-29 |
2018-10-04 |
Taipei Medical University |
Antigen-specific t cells and uses thereof
|
|
SG11201909160WA
(en)
|
2017-04-11 |
2019-10-30 |
Inhibrx Inc |
Multispecific polypeptide constructs having constrained cd3 binding and methods of using the same
|
|
CN108690138A
(zh)
*
|
2017-04-12 |
2018-10-23 |
鸿运华宁（杭州）生物医药有限公司 |
一种能与人cd19或cd20和人cd3结合的双特异性抗体及其应用
|
|
CN115028727A
(zh)
|
2017-05-12 |
2022-09-09 |
哈普恩治疗公司 |
靶向msln的三特异性蛋白质及使用方法
|
|
BR112019023855B1
(pt)
|
2017-05-12 |
2021-11-30 |
Harpoon Therapeutics, Inc |
Proteínas de ligação à mesotelina
|
|
CA3064714A1
(en)
*
|
2017-05-23 |
2018-11-29 |
Dragonfly Therapeutics, Inc. |
A protein binding nkg2d, cd16 and a tumor-associated antigen
|
|
BR112019025188A2
(pt)
|
2017-06-01 |
2020-06-23 |
Cytomx Therapeutics, Inc. |
Anticorpos anti-pdl1 ativáveis e métodos de uso dos mesmos
|
|
EP3645048A4
(en)
*
|
2017-06-25 |
2021-06-16 |
Systimmune, Inc. |
MULTISPECIFIC ANTIBODIES AND THE METHOD OF MANUFACTURING AND USING THEREOF
|
|
TW201904588A
(zh)
*
|
2017-06-25 |
2019-02-01 |
美商西雅圖免疫公司 |
引導及導航控制蛋白質之製造及使用方法
|
|
US11787863B2
(en)
*
|
2017-06-25 |
2023-10-17 |
Systimmune, Inc. |
Multi-specific antibodies and methods of making and using thereof
|
|
EP3645050A4
(en)
*
|
2017-06-25 |
2021-08-11 |
Systimmune, Inc. |
Multi-specific antibodies and methods of making and using thereof
|
|
EP3655779A1
(en)
|
2017-07-20 |
2020-05-27 |
CytomX Therapeutics, Inc. |
Methods of qualitatively and/or quantitatively analyzing properties of activatable antibodies and uses thereof
|
|
EP3668545A2
(en)
|
2017-08-16 |
2020-06-24 |
Bristol-Myers Squibb Company |
Prodruggable antibodies, prodrugs thereof, and methods of use and making
|
|
IL273119B2
(en)
|
2017-09-08 |
2023-10-01 |
Maverick Therapeutics Inc |
Binding proteins are activated under limited conditions
|
|
IL315737A
(en)
|
2017-10-13 |
2024-11-01 |
Harpoon Therapeutics Inc |
B-cell maturation antigen-binding proteins
|
|
JP7084990B2
(ja)
|
2017-10-13 |
2022-06-15 |
ハープーン セラピューティクス，インク． |
三重特異性タンパク質と使用方法
|
|
AU2018347607B2
(en)
|
2017-10-14 |
2025-08-21 |
Cytomx Therapeutics, Inc. |
Antibodies, activatable antibodies, bispecific antibodies, and bispecific activatable antibodies and methods of use thereof
|
|
US20190201541A1
(en)
*
|
2017-12-11 |
2019-07-04 |
Triphase Accelerator U.S. Corporation |
Anti-cd22 antibody-maytansine conjugates, combinations, and methods of use thereof
|
|
GB201721338D0
(en)
|
2017-12-19 |
2018-01-31 |
Kymab Ltd |
Anti-icos Antibodies
|
|
CN118772287A
(zh)
|
2018-02-08 |
2024-10-15 |
豪夫迈·罗氏有限公司 |
双特异性抗原结合分子和使用方法
|
|
PE20220278A1
(es)
|
2018-02-08 |
2022-02-25 |
Dragonfly Therapeutics Inc |
Dominios variables de anticuerpos que se dirigen al receptor nkg2d
|
|
AU2019218125B2
(en)
|
2018-02-08 |
2025-03-13 |
Dragonfly Therapeutics, Inc. |
Combination therapy of cancer involving multi-specific binding proteins that activate natural killer cells
|
|
TW201942134A
(zh)
|
2018-02-20 |
2019-11-01 |
美商蜻蜓醫療公司 |
結合cd33、nkg2d及cd16之多特異性結合蛋白及使用方法
|
|
JP2021518603A
(ja)
|
2018-03-20 |
2021-08-02 |
シートムエックス セラピューティクス，インコーポレイテッド |
哺乳動物対象における活性化可能抗体種の定量薬理学モデリングのためのシステムおよび方法
|
|
WO2019200022A1
(en)
|
2018-04-11 |
2019-10-17 |
Inhibrx, Inc. |
Multispecific polypeptide constructs having constrained cd3 binding and related methods and uses
|
|
WO2019213444A1
(en)
|
2018-05-02 |
2019-11-07 |
Cytomx Therapeutics, Inc. |
Antibodies, activatable antibodies, bispecific antibodies, and bispecific activatable antibodies and methods of use thereof
|
|
US20210299286A1
(en)
|
2018-05-04 |
2021-09-30 |
Tagworks Pharmaceuticals B.V. |
Tetrazines for high click conjugation yield in vivo and high click release yield
|
|
EP3794023A1
(en)
|
2018-05-14 |
2021-03-24 |
Werewolf Therapeutics, Inc. |
Activatable interleukin 12 polypeptides and methods of use thereof
|
|
DK3794024T5
(da)
|
2018-05-14 |
2024-08-19 |
Werewolf Therapeutics Inc |
Aktiverbare interleukin-2 polypeptider og fremgangsmåder til anvendelse heraf
|
|
WO2019222283A1
(en)
|
2018-05-14 |
2019-11-21 |
Harpoon Therapeutics, Inc. |
Binding moiety for conditional activation of immunoglobulin molecules
|
|
WO2019236567A2
(en)
*
|
2018-06-04 |
2019-12-12 |
Trustees Of Tufts College |
Tumor microenvironment-activated drug-binder conjugated, and uses related thereto
|
|
KR20210009421A
(ko)
*
|
2018-06-14 |
2021-01-26 |
바이오아트라, 엘엘씨 |
다중 특이적 항체 구조체
|
|
TW202035451A
(zh)
|
2018-07-24 |
2020-10-01 |
美商英伊布里克斯公司 |
含有受限cd3結合域及受體結合區之多重特異性多肽構築體及其使用方法
|
|
WO2020028401A1
(en)
|
2018-07-31 |
2020-02-06 |
Amgen Inc. |
Pharmaceutical formulations of masked antibodies
|
|
EA202091888A1
(ru)
|
2018-08-08 |
2020-10-23 |
Драгонфлай Терапьютикс, Инк. |
Вариабельные домены антител, нацеленные на рецептор nkg2d
|
|
EA202190468A1
(ru)
|
2018-08-08 |
2021-07-06 |
Драгонфлай Терапьютикс, Инк. |
Мультиспецифические связывающие белки, которые связывают bcma, nkg2d и cd16, и способы их применения
|
|
KR20250112921A
(ko)
|
2018-08-08 |
2025-07-24 |
드래곤플라이 쎄라퓨틱스, 인크. |
Nkg2d, cd16 및 종양 관련 항원에 결합하는 단백질
|
|
US12195544B2
(en)
|
2018-09-21 |
2025-01-14 |
Harpoon Therapeutics, Inc. |
EGFR binding proteins and methods of use
|
|
CN113286817B
(zh)
|
2018-09-25 |
2025-01-28 |
哈普恩治疗公司 |
Dll3结合蛋白及使用方法
|
|
EP3860567A4
(en)
*
|
2018-10-01 |
2022-07-06 |
Amgen Inc. |
METHOD OF REDUCING AGGREGATION OF BISPECIFIC ANTIBODIES
|
|
US12331320B2
(en)
|
2018-10-10 |
2025-06-17 |
The Research Foundation For The State University Of New York |
Genome edited cancer cell vaccines
|
|
CA3115082A1
(en)
|
2018-10-11 |
2020-04-16 |
Inhibrx, Inc. |
B7h3 single domain antibodies and therapeutic compositions thereof
|
|
EP3864049A1
(en)
|
2018-10-11 |
2021-08-18 |
Inhibrx, Inc. |
Pd-1 single domain antibodies and therapeutic compositions thereof
|
|
WO2020076977A2
(en)
|
2018-10-11 |
2020-04-16 |
Inhibrx, Inc. |
Dll3 single domain antibodies and therapeutic compositions thereof
|
|
US20210340273A1
(en)
|
2018-10-11 |
2021-11-04 |
Inhlbrx, inc. |
5t4 single domain antibodies and therapeutic compositions thereof
|
|
CA3119390A1
(en)
|
2018-11-12 |
2020-05-22 |
Debiopharm International S.A. |
Antibiotic compounds, methods of manufacturing the same, pharmaceutical compositions containing the same and uses thereof
|
|
EP4592313A3
(en)
|
2019-03-05 |
2025-11-19 |
Takeda Pharmaceutical Company Limited |
Constrained conditionally activated binding proteins
|
|
MX2021013766A
(es)
|
2019-05-14 |
2022-02-21 |
Werewolf Therapeutics Inc |
Restos de separacion y metodos de uso de los mismos.
|
|
US12516128B2
(en)
|
2019-05-14 |
2026-01-06 |
Harpoon Therapeutics, Inc. |
EpCAM binding proteins and methods of use
|
|
IL288024B2
(en)
|
2019-05-14 |
2025-12-01 |
Provention Bio Inc |
Methods and compositions for preventing type
|
|
TWI905099B
(zh)
|
2019-05-21 |
2025-11-21 |
瑞士商諾華公司 |
Cd19 結合分子及其用途
|
|
US20220251206A1
(en)
|
2019-06-11 |
2022-08-11 |
Bristol-Myers Squibb Company |
Anti-ctla4 antibody prodruggable (probody) at a cdr position
|
|
WO2020250940A1
(ja)
*
|
2019-06-11 |
2020-12-17 |
小野薬品工業株式会社 |
免疫抑制剤
|
|
IL289094A
(en)
|
2019-06-17 |
2022-02-01 |
Tagworks Pharmaceuticals B V |
Tetrazines for increasing the speed and yield of the "click release" reaction
|
|
IL289093B2
(en)
|
2019-06-17 |
2025-02-01 |
Tagworks Pharmaceuticals B V |
Compounds for a fast and efficient "click release" reaction
|
|
KR20210043475A
(ko)
|
2019-10-10 |
2021-04-21 |
주식회사 와이바이오로직스 |
다중 특이적 융합 단백질 및 이의 용도
|
|
TW202134277A
(zh)
|
2019-11-05 |
2021-09-16 |
美商再生元醫藥公司 |
Ｎ—端ｓｃＦｖ多特異性結合分子
|
|
EP4054649A4
(en)
*
|
2019-11-06 |
2023-12-06 |
Systimmune, Inc. |
GUIDANCE AND NAVIGATION REGULATORY PROTEINS AND METHODS OF PRODUCTION AND USE THEREOF
|
|
AU2020384375A1
(en)
|
2019-11-14 |
2022-05-26 |
Werewolf Therapeutics, Inc. |
Activatable cytokine polypeptides and methods of use thereof
|
|
WO2021097800A1
(en)
*
|
2019-11-22 |
2021-05-27 |
Abl Bio Inc. |
Anti-pd-l1/anti-b7-h3 multispecific antibodies and uses thereof
|
|
KR20220110221A
(ko)
*
|
2019-12-06 |
2022-08-05 |
온코원 리서치 앤드 디벨롭먼트 게엠베하 |
항-oxMIF/항-CD3 이중특이적 항체 구축물
|
|
PE20221511A1
(es)
|
2019-12-13 |
2022-10-04 |
Genentech Inc |
Anticuerpos anti-ly6g6d y metodos de uso
|
|
KR20220148175A
(ko)
|
2020-01-29 |
2022-11-04 |
인히브릭스, 인크. |
Ｃｄ28 단일 도메인 항체 및 이의 다가 및 다중특이적 구조체
|
|
AU2021213840A1
(en)
*
|
2020-01-31 |
2022-09-29 |
Suzhou Zelgen Biopharmaceuticals Co. Ltd. |
Bispecific T cell engagers
|
|
IL295448A
(en)
|
2020-02-21 |
2022-10-01 |
Harpoon Therapeutics Inc |
flt3 binding proteins and methods of use
|
|
TWI908779B
(zh)
*
|
2020-03-17 |
2025-12-21 |
美商西雅圖免疫公司 |
引導及導航控制(gnc)抗體樣蛋白質及製造與使用其之方法
|
|
MX2022011780A
(es)
|
2020-04-09 |
2022-11-10 |
Cytomx Therapeutics Inc |
Composiciones que contienen anticuerpos activables.
|
|
EP4146271A4
(en)
|
2020-05-06 |
2024-09-04 |
Dragonfly Therapeutics, Inc. |
PROTEINS THAT BIND NKG2D, CD16 AND CLEC12A
|
|
US12006366B2
(en)
|
2020-06-11 |
2024-06-11 |
Provention Bio, Inc. |
Methods and compositions for preventing type 1 diabetes
|
|
US12122839B2
(en)
|
2020-08-05 |
2024-10-22 |
Synthekine, Inc. |
IFNGR binding synthetic cytokines and methods of use
|
|
US12157773B2
(en)
|
2020-08-05 |
2024-12-03 |
Synthekine, Inc. |
IL27RAlpha binding molecules and methods of use
|
|
CN116322754A
(zh)
|
2020-08-05 |
2023-06-23 |
辛德凯因股份有限公司 |
Il10ra结合分子及使用方法
|
|
WO2022031929A1
(en)
|
2020-08-05 |
2022-02-10 |
Synthekine, Inc. |
Il12rb1-binding molecules and methods of use
|
|
WO2022032037A1
(en)
*
|
2020-08-05 |
2022-02-10 |
Synthekine, Inc. |
Il23 receptor synthetic cytokines and methods of use
|
|
WO2022032005A2
(en)
|
2020-08-05 |
2022-02-10 |
Synthekine, Inc. |
Il10rb binding molecules and methods of use
|
|
US12018085B2
(en)
|
2020-08-05 |
2024-06-25 |
Synthekine, Inc. |
Interferon-gamma R2 (IFNGR2) binding molecules comprising single-domain antibodies and method of use thereof to treat autoimmune and inflammatory diseases
|
|
AU2021320226A1
(en)
|
2020-08-05 |
2023-03-23 |
Synthekine, Inc. |
gp130 binding molecules and methods of use
|
|
US12540188B2
(en)
|
2020-08-05 |
2026-02-03 |
Synthekine, Inc. |
IL10Rα/IL2Rγ synthetic cytokines
|
|
WO2022032042A1
(en)
|
2020-08-05 |
2022-02-10 |
Synthekine, Inc. |
Il12 receptor synthetic cytokines and methods of use
|
|
US12077594B2
(en)
|
2020-08-05 |
2024-09-03 |
Synthekine, Inc. |
IL2RG binding molecules and methods of use
|
|
EP4192502A4
(en)
|
2020-08-05 |
2024-10-09 |
Synthekine, Inc. |
Compositions and methods related to il27 receptor binding
|
|
CA3190486A1
(en)
|
2020-08-05 |
2022-02-10 |
Synthekine, Inc. |
Il10 receptor binding molecules and methods of use
|
|
WO2022032023A2
(en)
|
2020-08-05 |
2022-02-10 |
Synthekine, Inc. |
Il23r binding molecules and methods of use
|
|
WO2022032006A2
(en)
|
2020-08-05 |
2022-02-10 |
Synthekine, Inc. |
Il2rb binding molecules and methods of use
|
|
US20240034806A1
(en)
*
|
2020-12-09 |
2024-02-01 |
Janux Therapeutics, Inc. |
Compositions and methods related to tumor activated antibodies targeting trop2 and effector cell antigens
|
|
WO2022170619A1
(en)
*
|
2021-02-11 |
2022-08-18 |
Adagene Pte. Ltd. |
Anti-cd3 antibodies and methods of use thereof
|
|
US12377144B2
(en)
|
2021-03-03 |
2025-08-05 |
Dragonfly Therapeutics, Inc. |
Methods of treating cancer using multi-specific binding proteins that bind NKG2D, CD16 and a tumor-associated antigen
|
|
EP4319814A4
(en)
*
|
2021-04-08 |
2025-03-26 |
Board of Regents, The University of Texas System |
Methods for activation and expansion of natural killer cells and combinations with bispecific antibodies
|
|
WO2022241235A1
(en)
|
2021-05-14 |
2022-11-17 |
Genentech, Inc. |
Methods for treatment of cd20-positive proliferative disorder with mosunetuzumab and polatuzumab vedotin
|
|
MX2023013851A
(es)
|
2021-05-24 |
2023-12-08 |
Provention Bio Inc |
Metodos para el tratamiento de diabetes tipo 1.
|
|
CN118103405A
(zh)
|
2021-10-15 |
2024-05-28 |
西托姆克斯治疗公司 |
可激活多肽复合物
|
|
WO2023064955A1
(en)
|
2021-10-15 |
2023-04-20 |
Cytomx Therapeutics, Inc. |
Activatable anti-cd3, anti-egfr, heteromultimeric bispecific polypeptide complex
|
|
EP4416178A1
(en)
|
2021-10-15 |
2024-08-21 |
CytomX Therapeutics, Inc. |
Activatable polypeptide complex
|
|
KR20240101682A9
(ko)
|
2021-11-15 |
2025-12-10 |
시스트이뮨, 인코포레이티드 |
이중특이 항체-캄프토테신 약물 접합체 및 이의 약학적 용도
|
|
WO2023150672A1
(en)
*
|
2022-02-04 |
2023-08-10 |
Duke University |
Compositions for and methods of treating hematological cancers
|
|
TW202342739A
(zh)
*
|
2022-02-11 |
2023-11-01 |
美商英特瑞斯生物療法公司 |
融合性彈狀病毒醣蛋白及其用途
|
|
CN114316062B
(zh)
*
|
2022-03-02 |
2022-06-07 |
珠海臻谱基因科技有限公司北京分公司 |
靶向HIV gp120蛋白和人CD3分子的多特异性抗体及其应用
|
|
WO2023201291A1
(en)
|
2022-04-13 |
2023-10-19 |
Genentech, Inc. |
Pharmaceutical compositions of mosunetuzumab and methods of use
|
|
JP2025537782A
(ja)
*
|
2022-11-15 |
2025-11-20 |
エフ． ホフマン－ラ ロシュ アーゲー |
活性化可能なエフェクタードメインを有する組換え結合タンパク質
|
|
WO2025036848A1
(en)
|
2023-08-11 |
2025-02-20 |
Wuxi Biologics (Shanghai) Co., Ltd. |
Anti-muc16 antibodies and uses thereof
|
|
CN121712801A
(zh)
|
2023-08-14 |
2026-03-20 |
莫佛塞斯有限责任公司 |
包含空间位阻部分的CyCAT半体分子
|
|
WO2025038668A1
(en)
|
2023-08-14 |
2025-02-20 |
Voro Therapeutics, Inc. |
Therapeutic binding agents that conditionally promote myeloid cell activity against target cells and uses thereof
|
|
TW202540200A
(zh)
|
2023-12-01 |
2025-10-16 |
美商基利科學股份有限公司 |
抗ｆａｐ－ｌｉｇｈｔ融合蛋白及其用途
|
|
WO2025189116A1
(en)
*
|
2024-03-08 |
2025-09-12 |
Synthetic Design Lab, Inc. |
Multivalent multispecific constructs for targeted payload delivery
|
|
US20250297006A1
(en)
*
|
2024-03-20 |
2025-09-25 |
Regeneron Pharmaceuticals, Inc. |
Masked Multispecific Antigen-Binding Molecules with Cleavable Linkers
|
|
WO2025235515A1
(en)
|
2024-05-07 |
2025-11-13 |
Cytomx Therapeutics, Inc. |
Activatable polypeptide complex formulations
|
|
WO2025240659A2
(en)
|
2024-05-14 |
2025-11-20 |
Cytomx Therapeutics, Inc. |
Activatable constructs, compositions and methods
|
|
WO2025237931A1
(en)
*
|
2024-05-15 |
2025-11-20 |
F. Hoffmann-La Roche Ag |
Recombinant binding proteins with conditionally activatable t cell and nk cell recruiting effector domains
|
|
US20260056209A1
(en)
|
2024-06-14 |
2026-02-26 |
Gilead Sciences, Inc. |
Anti-ccr8 antibodies and uses thereof
|
|
WO2026024841A1
(en)
*
|
2024-07-24 |
2026-01-29 |
Astellas Us Llc |
Bispecific antibodies that bind cd3 and muc1 and methods of use thereof
|