JP2017512825A5 - - Google Patents
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- Publication number
- JP2017512825A5 JP2017512825A5 JP2016561611A JP2016561611A JP2017512825A5 JP 2017512825 A5 JP2017512825 A5 JP 2017512825A5 JP 2016561611 A JP2016561611 A JP 2016561611A JP 2016561611 A JP2016561611 A JP 2016561611A JP 2017512825 A5 JP2017512825 A5 JP 2017512825A5
- Authority
- JP
- Japan
- Prior art keywords
- agent according
- antibody
- nme7
- seq
- nos
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000003795 chemical substances by application Substances 0.000 claims 15
- 108090000765 processed proteins & peptides Proteins 0.000 claims 4
- 101001128732 Homo sapiens Nucleoside diphosphate kinase 7 Proteins 0.000 claims 3
- 102100032115 Nucleoside diphosphate kinase 7 Human genes 0.000 claims 3
- 101001133056 Homo sapiens Mucin-1 Proteins 0.000 claims 1
- 101000979629 Homo sapiens Nucleoside diphosphate kinase A Proteins 0.000 claims 1
- 102000008394 Immunoglobulin Fragments Human genes 0.000 claims 1
- 108010021625 Immunoglobulin Fragments Proteins 0.000 claims 1
- 102100034256 Mucin-1 Human genes 0.000 claims 1
- 101100346932 Mus musculus Muc1 gene Proteins 0.000 claims 1
- 206010028980 Neoplasm Diseases 0.000 claims 1
- 102100023252 Nucleoside diphosphate kinase A Human genes 0.000 claims 1
- 125000000539 amino acid group Chemical group 0.000 claims 1
- 201000011510 cancer Diseases 0.000 claims 1
- 230000003278 mimic effect Effects 0.000 claims 1
- 102000004196 processed proteins & peptides Human genes 0.000 claims 1
- 230000000069 prophylactic effect Effects 0.000 claims 1
- 108090000623 proteins and genes Proteins 0.000 claims 1
- 102000004169 proteins and genes Human genes 0.000 claims 1
- 230000001225 therapeutic effect Effects 0.000 claims 1
Applications Claiming Priority (11)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201461976390P | 2014-04-07 | 2014-04-07 | |
| US61/976,390 | 2014-04-07 | ||
| PCT/US2014/050773 WO2015023694A2 (en) | 2013-08-12 | 2014-08-12 | Method for enhancing tumor growth |
| USPCT/US2014/050773 | 2014-08-12 | ||
| USPCT/US2014/061821 | 2014-10-22 | ||
| USPCT/US2014/061821 | 2014-10-22 | ||
| US201562114526P | 2015-02-10 | 2015-02-10 | |
| US62/114,526 | 2015-02-10 | ||
| US201562127746P | 2015-03-03 | 2015-03-03 | |
| US62/127,746 | 2015-03-03 | ||
| PCT/US2015/024764 WO2015157322A2 (en) | 2014-04-07 | 2015-04-07 | Anti-nme antibody |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018165618A Division JP6646118B2 (ja) | 2014-04-07 | 2018-09-05 | 抗ｎｍｅ抗体 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017512825A JP2017512825A (ja) | 2017-05-25 |
| JP2017512825A5 true JP2017512825A5 (enExample) | 2017-07-06 |
| JP6401292B2 JP6401292B2 (ja) | 2018-10-10 |
Family
ID=54288530
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016561611A Active JP6401292B2 (ja) | 2014-04-07 | 2015-04-07 | 抗ｎｍｅ抗体 |
| JP2018165618A Active JP6646118B2 (ja) | 2014-04-07 | 2018-09-05 | 抗ｎｍｅ抗体 |
| JP2020001446A Active JP7042854B2 (ja) | 2014-04-07 | 2020-01-08 | 抗ｎｍｅ抗体 |
| JP2022040438A Pending JP2022095648A (ja) | 2014-04-07 | 2022-03-15 | 抗ｎｍｅ抗体 |
| JP2024032381A Pending JP2024084747A (ja) | 2014-04-07 | 2024-03-04 | 抗ｎｍｅ抗体 |
Family Applications After (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018165618A Active JP6646118B2 (ja) | 2014-04-07 | 2018-09-05 | 抗ｎｍｅ抗体 |
| JP2020001446A Active JP7042854B2 (ja) | 2014-04-07 | 2020-01-08 | 抗ｎｍｅ抗体 |
| JP2022040438A Pending JP2022095648A (ja) | 2014-04-07 | 2022-03-15 | 抗ｎｍｅ抗体 |
| JP2024032381A Pending JP2024084747A (ja) | 2014-04-07 | 2024-03-04 | 抗ｎｍｅ抗体 |
Country Status (11)
| Country | Link |
|---|---|
| US (4) | US20170204196A1 (enExample) |
| EP (2) | EP4050103A1 (enExample) |
| JP (5) | JP6401292B2 (enExample) |
| KR (2) | KR20210107166A (enExample) |
| CN (1) | CN106414726A (enExample) |
| AU (1) | AU2015243948B2 (enExample) |
| CA (1) | CA2945162A1 (enExample) |
| IL (2) | IL248220A0 (enExample) |
| SG (2) | SG11201608389RA (enExample) |
| TW (1) | TWI746420B (enExample) |
| WO (1) | WO2015157322A2 (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2945162A1 (en) | 2014-04-07 | 2015-10-15 | Minerva Biotechnologies Corporation | Use of an anti-nme antibody for treatment or prevention of cancer |
| CN116199790A (zh) | 2015-02-10 | 2023-06-02 | 米纳瓦生物技术公司 | 人源化抗MUCl*抗体 |
| WO2018071583A2 (en) * | 2016-10-11 | 2018-04-19 | Minerva Biotechnologies Corporation | Humanized anti-muc1* antibodies and use of cleavage enzyme |
| IL302144A (en) * | 2017-03-29 | 2023-06-01 | Minerva Biotechnologies Corp | Agents for stem cell differentiation and cancer treatment |
| WO2020163325A1 (en) * | 2019-02-04 | 2020-08-13 | Minerva Biotechnologies Corporation | Anti-nme antibody and method of treating cancer or cancer metastasis |
| US12049514B2 (en) | 2020-06-08 | 2024-07-30 | Minerva Biotechnologies Corporation | Anti-NME antibody and method of treating cancer or cancer metastasis |
| US20230242678A1 (en) * | 2020-06-26 | 2023-08-03 | Minerva Biotechnologies Corporation | Anti-nme antibody and method of treating cancer or cancer metastasis |
| IL316221A (en) | 2022-04-12 | 2024-12-01 | Minerva Biotechnologies Corp | Anti-MUC1* variant antibodies and their uses |
| US20240261406A1 (en) | 2023-02-02 | 2024-08-08 | Minerva Biotechnologies Corporation | Chimeric antigen receptor compositions and methods for treating muc1* diseases |
| WO2025049494A1 (en) | 2023-08-29 | 2025-03-06 | Minerva Biotechnologies Corporation | Bacterial nme7 orthologs and uses thereof |
Family Cites Families (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| US5631271A (en) | 1986-11-29 | 1997-05-20 | Serfontein; Willem J. | Methods and preparations for the treatment and prophylaxis of metabolic disturbances |
| US5874285A (en) * | 1996-09-13 | 1999-02-23 | Incyte Pharmaceuticals, Inc. | Polynucleotide encoding a novel human nm23-like protein |
| US6818749B1 (en) | 1998-10-31 | 2004-11-16 | The United States Of America As Represented By The Department Of Health And Human Services | Variants of humanized anti carcinoma monoclonal antibody cc49 |
| CA2384713A1 (en) | 1999-09-29 | 2001-04-05 | Human Genome Sciences, Inc. | Colon and colon cancer associated polynucleotides and polypeptides |
| AUPR011700A0 (en) | 2000-09-14 | 2000-10-05 | Austin Research Institute, The | Composition comprising immunogenic virus sized particles (VSP) |
| US20050163784A1 (en) | 2002-06-17 | 2005-07-28 | Valentijn Linda J. | Novel cancer therapies |
| WO2004005470A2 (en) * | 2002-07-03 | 2004-01-15 | Immunogen, Inc. | Antibodies to non-shed muc1 and muc16, and uses thereof |
| AU2003299643A1 (en) * | 2002-12-04 | 2004-06-23 | Diadexus, Inc. | Compositions, splice variants and methods relating to colon specific genes and proteins |
| CA2611728A1 (en) | 2005-06-08 | 2006-12-14 | Millennium Pharmaceuticals, Inc. | Methods for the identification, assessment, and treatment of patients with cancer therapy |
| WO2007072221A2 (en) | 2005-11-10 | 2007-06-28 | Aurelium Biopharma Inc. | Surface marker-directed cancer therapeutics |
| JP2010530437A (ja) | 2007-06-18 | 2010-09-09 | メディミューン，エルエルシー | ＥｐｈＡ２およびＥｒｂＢ２を発現する細胞の相乗的治療 |
| US8273541B2 (en) | 2008-09-17 | 2012-09-25 | Innate Pharma | Compositions and methods for detecting TLR3 |
| WO2010042562A2 (en) | 2008-10-06 | 2010-04-15 | Minerva Biotechnologies Corporation | Muc1* antibodies |
| US20110195089A1 (en) | 2008-10-08 | 2011-08-11 | The Adminstrators Of The Tulane Educational Fund | Compositions, methods, and kits for enhancing the immunogenicity of pathogenic antigens |
| MX2011013385A (es) * | 2009-06-11 | 2012-05-29 | Minerva Biotechnologies Corp | Metodos para cultivar celulas madre y celulas progenitoras. |
| PH12013501201A1 (en) * | 2010-12-09 | 2013-07-29 | Univ Pennsylvania | Use of chimeric antigen receptor-modified t cells to treat cancer |
| CN103998598A (zh) * | 2011-10-17 | 2014-08-20 | 米纳瓦生物技术公司 | 用于干细胞增殖和诱导的培养基 |
| US9814782B2 (en) | 2012-02-24 | 2017-11-14 | Alteogen Inc. | Modified antibody in which motif comprising cysteine residue is bound, modified antibody-drug conjugate comprising the modified antibody, and production method for same |
| JP6189415B2 (ja) * | 2012-04-02 | 2017-08-30 | モデルナティエックス インコーポレイテッドＭｏｄｅｒｎａＴＸ，Ｉｎｃ． | 細胞質および細胞骨格タンパク質の産生のための修飾ポリヌクレオチド |
| CA2880010A1 (en) * | 2012-07-24 | 2014-01-30 | Minerva Biotechnologies Corporation | Nme variant species expression and suppression |
| AU2013302620B2 (en) * | 2012-08-14 | 2018-08-02 | Minerva Biotechnologies Corporation | Stem cell enhancing therapeutics |
| US9770011B2 (en) | 2012-09-29 | 2017-09-26 | The Trustees Of The University Of Pennsylvania | Veterinary composition and methods for non-surgical neutering and castration |
| US20160326263A1 (en) | 2013-02-20 | 2016-11-10 | Minerva Biotechnologies Corporation | NME Inhibitors and Methods of Using NME Inhibitors |
| WO2014130741A2 (en) * | 2013-02-20 | 2014-08-28 | Minerva Biotechnologies Corporation | Nme inhibitors and methods of using nme inhibitors |
| CA2945162A1 (en) | 2014-04-07 | 2015-10-15 | Minerva Biotechnologies Corporation | Use of an anti-nme antibody for treatment or prevention of cancer |
| CN116199790A (zh) | 2015-02-10 | 2023-06-02 | 米纳瓦生物技术公司 | 人源化抗MUCl*抗体 |
| CN105384825B (zh) | 2015-08-11 | 2018-06-01 | 南京传奇生物科技有限公司 | 一种基于单域抗体的双特异性嵌合抗原受体及其应用 |
| CN107074943B (zh) | 2016-07-14 | 2018-08-24 | 中国科学院生物物理研究所 | I型干扰素受体抗体及其用途 |
| US20200165354A1 (en) | 2016-09-20 | 2020-05-28 | WuXi Biologics Ireland Limited | Novel Anti-PCSK9 Antibodies |
| WO2018071583A2 (en) | 2016-10-11 | 2018-04-19 | Minerva Biotechnologies Corporation | Humanized anti-muc1* antibodies and use of cleavage enzyme |
| US20200390870A1 (en) | 2017-11-27 | 2020-12-17 | Minerva Biotechnologies Corporation | Humanized anti-muc1* antibodies and direct use of cleavage enzyme |
| WO2020163325A1 (en) | 2019-02-04 | 2020-08-13 | Minerva Biotechnologies Corporation | Anti-nme antibody and method of treating cancer or cancer metastasis |
| US12049514B2 (en) | 2020-06-08 | 2024-07-30 | Minerva Biotechnologies Corporation | Anti-NME antibody and method of treating cancer or cancer metastasis |
| US20230242678A1 (en) | 2020-06-26 | 2023-08-03 | Minerva Biotechnologies Corporation | Anti-nme antibody and method of treating cancer or cancer metastasis |
-
2015
- 2015-04-07 CA CA2945162A patent/CA2945162A1/en active Pending
- 2015-04-07 US US15/302,461 patent/US20170204196A1/en not_active Abandoned
- 2015-04-07 JP JP2016561611A patent/JP6401292B2/ja active Active
- 2015-04-07 KR KR1020217026634A patent/KR20210107166A/ko not_active Withdrawn
- 2015-04-07 KR KR1020167030925A patent/KR102294483B1/ko active Active
- 2015-04-07 SG SG11201608389RA patent/SG11201608389RA/en unknown
- 2015-04-07 EP EP21217415.5A patent/EP4050103A1/en active Pending
- 2015-04-07 EP EP15776097.6A patent/EP3129476B1/en active Active
- 2015-04-07 AU AU2015243948A patent/AU2015243948B2/en active Active
- 2015-04-07 TW TW104111213A patent/TWI746420B/zh active
- 2015-04-07 SG SG10201808867PA patent/SG10201808867PA/en unknown
- 2015-04-07 WO PCT/US2015/024764 patent/WO2015157322A2/en not_active Ceased
- 2015-04-07 CN CN201580030021.0A patent/CN106414726A/zh active Pending
-
2016
- 2016-10-06 IL IL248220A patent/IL248220A0/en unknown
-
2018
- 2018-08-24 US US16/111,862 patent/US20190031778A1/en not_active Abandoned
- 2018-08-24 US US16/111,894 patent/US11702483B2/en active Active
- 2018-09-05 JP JP2018165618A patent/JP6646118B2/ja active Active
-
2020
- 2020-01-08 JP JP2020001446A patent/JP7042854B2/ja active Active
-
2022
- 2022-03-07 IL IL291164A patent/IL291164A/en unknown
- 2022-03-15 JP JP2022040438A patent/JP2022095648A/ja active Pending
- 2022-04-12 US US17/719,302 patent/US12479928B2/en active Active
-
2024
- 2024-03-04 JP JP2024032381A patent/JP2024084747A/ja active Pending
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