JP2020507561A5 - - Google Patents
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- JP2020507561A5 JP2020507561A5 JP2019538396A JP2019538396A JP2020507561A5 JP 2020507561 A5 JP2020507561 A5 JP 2020507561A5 JP 2019538396 A JP2019538396 A JP 2019538396A JP 2019538396 A JP2019538396 A JP 2019538396A JP 2020507561 A5 JP2020507561 A5 JP 2020507561A5
- Authority
- JP
- Japan
- Prior art keywords
- antibody
- antigen
- binding fragment
- seq
- amino acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022107980A JP2022153405A (ja) | 2017-01-30 | 2022-07-04 | 一価の抗プロペルジン抗体および抗体断片 |
| JP2024095141A JP2024116321A (ja) | 2017-01-30 | 2024-06-12 | 一価の抗プロペルジン抗体および抗体断片 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762452187P | 2017-01-30 | 2017-01-30 | |
| US62/452,187 | 2017-01-30 | ||
| PCT/US2018/015985 WO2018140956A1 (en) | 2017-01-30 | 2018-01-30 | Monovalent anti-properdin antibodies and antibody fragments |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022107980A Division JP2022153405A (ja) | 2017-01-30 | 2022-07-04 | 一価の抗プロペルジン抗体および抗体断片 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020507561A JP2020507561A (ja) | 2020-03-12 |
| JP2020507561A5 true JP2020507561A5 (enExample) | 2021-03-04 |
| JP7101684B2 JP7101684B2 (ja) | 2022-07-15 |
Family
ID=62978808
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019538396A Active JP7101684B2 (ja) | 2017-01-30 | 2018-01-30 | 一価の抗プロペルジン抗体および抗体断片 |
| JP2022107980A Pending JP2022153405A (ja) | 2017-01-30 | 2022-07-04 | 一価の抗プロペルジン抗体および抗体断片 |
| JP2024095141A Pending JP2024116321A (ja) | 2017-01-30 | 2024-06-12 | 一価の抗プロペルジン抗体および抗体断片 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022107980A Pending JP2022153405A (ja) | 2017-01-30 | 2022-07-04 | 一価の抗プロペルジン抗体および抗体断片 |
| JP2024095141A Pending JP2024116321A (ja) | 2017-01-30 | 2024-06-12 | 一価の抗プロペルジン抗体および抗体断片 |
Country Status (12)
| Country | Link |
|---|---|
| US (3) | US11198725B2 (enExample) |
| EP (1) | EP3573661A4 (enExample) |
| JP (3) | JP7101684B2 (enExample) |
| KR (2) | KR20230173731A (enExample) |
| CN (2) | CN118184777A (enExample) |
| AU (2) | AU2018212012B2 (enExample) |
| BR (1) | BR112019014652A2 (enExample) |
| CA (1) | CA3049806A1 (enExample) |
| CO (1) | CO2019007686A2 (enExample) |
| IL (2) | IL309890A (enExample) |
| MX (3) | MX2019008827A (enExample) |
| WO (1) | WO2018140956A1 (enExample) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL309890A (en) * | 2017-01-30 | 2024-03-01 | Alexion Pharma Inc | Monovalent anti-properdin antibodies and antibody fragments |
| IL307197B1 (en) * | 2017-07-11 | 2025-11-01 | Alexion Pharma Inc | Polypeptides that bind complement component c5 or serum albumin and fusion proteins thereof |
| CN112969367B (zh) * | 2018-09-13 | 2023-04-07 | 瑞泽恩制药公司 | 作为c3肾小球病模型的补体因子h基因敲除大鼠 |
| JP7747639B2 (ja) | 2020-01-08 | 2025-10-01 | ザイダス・ライフサイエンシーズ・リミテッド | 抗プロペルジン抗体とその調製 |
| JP7787164B2 (ja) | 2020-09-23 | 2025-12-16 | アキリオン ファーマシューティカルズ， インコーポレーテッド | 補体媒介性障害の治療のための医薬化合物 |
| WO2022089576A1 (zh) * | 2020-10-30 | 2022-05-05 | 广州市妇女儿童医疗中心 | 用于抑制mhc-i和/或ii信号通路的试剂在治疗胆道闭锁中的应用 |
| WO2023023227A1 (en) | 2021-08-20 | 2023-02-23 | Alexion Pharmaceuticals, Inc. | Methods for treating sickle cell disease or beta thalassemia using complement alternative pathway inhibitors |
| US11981727B2 (en) | 2021-08-31 | 2024-05-14 | Novelmed Therapeutics, Inc | Monospecific and bispecific antibodies and antigen binding fragments thereof |
| WO2024108529A1 (en) * | 2022-11-25 | 2024-05-30 | Linno Pharmaceuticals Inc. | Properdin binding protein and use thereof |
| WO2024031049A2 (en) * | 2022-08-05 | 2024-02-08 | Alexion Pharmaceuticals, Inc. | Pharmaceutical compositions of fusion proteins and methods of use thereof |
| EP4580749A1 (en) * | 2022-08-31 | 2025-07-09 | Alexion Pharmaceuticals, Inc. | Dosage and administration of fusion polypeptides for treatment of sickle cell disease |
| KR20250112858A (ko) | 2022-11-25 | 2025-07-24 | 리노 파마슈티컬스 아이엔씨. | 프로퍼딘 결합 단백질 및 이의 용도 |
| CN116514983B (zh) * | 2023-06-02 | 2025-05-23 | 安徽金百奥生物科技有限公司 | 一种靶向dr3胞外域的纳米抗体及其应用 |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2637801T3 (es) | 2000-04-11 | 2017-10-17 | Genentech, Inc. | Anticuerpos multivalentes y usos de los mismos |
| US7423128B2 (en) | 2004-11-03 | 2008-09-09 | Amgen Fremont Inc. | Anti-properdin antibodies, and methods for making and using same |
| CN103172747A (zh) | 2005-01-25 | 2013-06-26 | 细胞治疗学公司 | 体内半衰期改变的生物活性蛋白质偶联物 |
| US7612181B2 (en) | 2005-08-19 | 2009-11-03 | Abbott Laboratories | Dual variable domain immunoglobulin and uses thereof |
| HUE026423T2 (en) | 2005-11-04 | 2016-05-30 | Genentech Inc | Use of complement biosynthetic pathway inhibitors for treating eye diseases |
| GB0624500D0 (en) * | 2006-12-07 | 2007-01-17 | Istituto Superiore Di Sanito | A novel passive vaccine for candida infections |
| WO2011112850A2 (en) * | 2010-03-10 | 2011-09-15 | Novelmed Therapeutics, Inc. | Humanized and chimeric anti-properdin antibodies |
| PL2262831T3 (pl) * | 2008-03-03 | 2015-08-31 | Novelmed Therapeutics Inc | Przeciwciała przeciwko properdynie |
| US20110002931A1 (en) | 2009-06-23 | 2011-01-06 | Alexion Pharmaceuticals, Inc. | Bispecific antibodies that bind to complement proteins |
| UY32920A (es) | 2009-10-02 | 2011-04-29 | Boehringer Ingelheim Int | Moleculas de unión biespecíficas para la terapia anti-angiogénesis |
| PT2621515T (pt) | 2010-09-28 | 2017-07-12 | Aegerion Pharmaceuticals Inc | Polipéptido quimérico de leptina de foca-ser humano com solubilidade aumentada |
| JP5933573B2 (ja) | 2010-11-08 | 2016-06-15 | ノバルティス アーゲー | Ｃｘｃｒ２結合ポリペプチド |
| JP6293659B2 (ja) | 2011-07-01 | 2018-03-14 | ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア | 抗プロペルジン抗体およびその使用 |
| CN104271588B (zh) * | 2011-07-08 | 2017-10-10 | 安米林药品有限责任公司 | 具有增强的作用持续时间和降低的免疫原性的工程改造的多肽 |
| PE20150159A1 (es) * | 2011-12-21 | 2015-02-08 | Novartis Ag | Composiciones y metodos para anticuerpos que actuan sobre el factor p |
| AU2012362217A1 (en) * | 2011-12-28 | 2014-07-24 | Novelmed Therapeutics, Inc. | Aglycosylated human antibody and fusion protein and uses thereof |
| CN104870474B (zh) * | 2012-10-04 | 2019-03-12 | 诺沃姆德治疗公司 | 用于治疗溶血性疾病的旁路途径特异性抗体 |
| NL2013661B1 (en) | 2014-10-21 | 2016-10-05 | Ablynx Nv | KV1.3 Binding immunoglobulins. |
| CA2874083C (en) * | 2014-12-05 | 2024-01-02 | Universite Laval | Tdp-43-binding polypeptides useful for the treatment of neurodegenerative diseases |
| IL309890A (en) * | 2017-01-30 | 2024-03-01 | Alexion Pharma Inc | Monovalent anti-properdin antibodies and antibody fragments |
| CN110003335B (zh) * | 2019-04-12 | 2023-07-04 | 深圳普瑞金生物药业股份有限公司 | Cd47单域抗体、核酸及试剂盒 |
-
2018
- 2018-01-30 IL IL309890A patent/IL309890A/en unknown
- 2018-01-30 IL IL267898A patent/IL267898B2/en unknown
- 2018-01-30 AU AU2018212012A patent/AU2018212012B2/en active Active
- 2018-01-30 MX MX2019008827A patent/MX2019008827A/es unknown
- 2018-01-30 KR KR1020237042534A patent/KR20230173731A/ko not_active Ceased
- 2018-01-30 US US16/479,335 patent/US11198725B2/en active Active
- 2018-01-30 BR BR112019014652-0A patent/BR112019014652A2/pt active Search and Examination
- 2018-01-30 EP EP18744926.9A patent/EP3573661A4/en active Pending
- 2018-01-30 CN CN202410325026.7A patent/CN118184777A/zh active Pending
- 2018-01-30 KR KR1020197021910A patent/KR102613874B1/ko active Active
- 2018-01-30 CN CN201880008892.6A patent/CN110831626B/zh active Active
- 2018-01-30 CA CA3049806A patent/CA3049806A1/en active Pending
- 2018-01-30 WO PCT/US2018/015985 patent/WO2018140956A1/en not_active Ceased
- 2018-01-30 JP JP2019538396A patent/JP7101684B2/ja active Active
-
2019
- 2019-07-17 CO CONC2019/0007686A patent/CO2019007686A2/es unknown
- 2019-07-25 MX MX2023007840A patent/MX2023007840A/es unknown
- 2019-07-25 MX MX2023004333A patent/MX2023004333A/es unknown
-
2021
- 2021-11-09 US US17/522,028 patent/US12497445B2/en active Active
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2022
- 2022-07-04 JP JP2022107980A patent/JP2022153405A/ja active Pending
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2024
- 2024-06-12 JP JP2024095141A patent/JP2024116321A/ja active Pending
-
2025
- 2025-02-03 AU AU2025200709A patent/AU2025200709A1/en active Pending
- 2025-11-13 US US19/387,895 patent/US20260070963A1/en active Pending