JP2010538619A5 - - Google Patents
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- Publication number
- JP2010538619A5 JP2010538619A5 JP2010524318A JP2010524318A JP2010538619A5 JP 2010538619 A5 JP2010538619 A5 JP 2010538619A5 JP 2010524318 A JP2010524318 A JP 2010524318A JP 2010524318 A JP2010524318 A JP 2010524318A JP 2010538619 A5 JP2010538619 A5 JP 2010538619A5
- Authority
- JP
- Japan
- Prior art keywords
- mamv
- coat protein
- vlp
- seq
- amino acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 241000850834 Malva mosaic virus Species 0.000 claims 37
- 101710132601 Capsid protein Proteins 0.000 claims 27
- 101710094648 Coat protein Proteins 0.000 claims 27
- 102100021181 Golgi phosphoprotein 3 Human genes 0.000 claims 27
- 101710125418 Major capsid protein Proteins 0.000 claims 27
- 101710141454 Nucleoprotein Proteins 0.000 claims 27
- 101710083689 Probable capsid protein Proteins 0.000 claims 27
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 15
- 125000003275 alpha amino acid group Chemical group 0.000 claims 15
- 239000008194 pharmaceutical composition Substances 0.000 claims 14
- 239000000427 antigen Substances 0.000 claims 11
- 102000036639 antigens Human genes 0.000 claims 11
- 108091007433 antigens Proteins 0.000 claims 11
- 108020001507 fusion proteins Proteins 0.000 claims 7
- 102000037865 fusion proteins Human genes 0.000 claims 7
- 238000000034 method Methods 0.000 claims 7
- 239000002245 particle Substances 0.000 claims 7
- 241001465754 Metazoa Species 0.000 claims 5
- 230000028993 immune response Effects 0.000 claims 4
- 102000040430 polynucleotide Human genes 0.000 claims 3
- 108091033319 polynucleotide Proteins 0.000 claims 3
- 239000002157 polynucleotide Substances 0.000 claims 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 2
- 239000003937 drug carrier Substances 0.000 claims 2
- 230000002708 enhancing effect Effects 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- 241000588724 Escherichia coli Species 0.000 claims 1
- 241000124008 Mammalia Species 0.000 claims 1
- 230000001580 bacterial effect Effects 0.000 claims 1
- 230000036755 cellular response Effects 0.000 claims 1
- 201000010099 disease Diseases 0.000 claims 1
- 208000035475 disorder Diseases 0.000 claims 1
- 208000015181 infectious disease Diseases 0.000 claims 1
- 238000002347 injection Methods 0.000 claims 1
- 239000007924 injection Substances 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US97148607P | 2007-09-11 | 2007-09-11 | |
| PCT/CA2008/001603 WO2009033276A1 (en) | 2007-09-11 | 2008-09-11 | Malva mosaic virus and virus-like particles and uses thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2010538619A JP2010538619A (ja) | 2010-12-16 |
| JP2010538619A5 true JP2010538619A5 (enExample) | 2011-11-04 |
Family
ID=40451518
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010524318A Pending JP2010538619A (ja) | 2007-09-11 | 2008-09-11 | Ｍａｌｖａモザイクウイルスおよびウイルス様粒子およびこれらの使用 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20110104191A1 (enExample) |
| EP (1) | EP2201106A4 (enExample) |
| JP (1) | JP2010538619A (enExample) |
| CA (1) | CA2699093A1 (enExample) |
| WO (1) | WO2009033276A1 (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6068630A (en) | 1997-01-02 | 2000-05-30 | St. Francis Medical Technologies, Inc. | Spine distraction implant |
| CN102573904B (zh) * | 2009-10-08 | 2016-02-10 | 阿昂梅迪克斯公司 | 含有源于室内空气的细胞外小泡的组合物及其用途 |
| WO2013003353A2 (en) * | 2011-06-30 | 2013-01-03 | Stc.Unm | Plasmids and methods for peptide display and affinity-selection on virus-like particles of rna bacteriophages |
| CA2786940C (en) | 2010-03-16 | 2019-09-24 | Biontech Ag | Tumor vaccination involving a humoral immune response, and proteins therefor including all or a portion of a hepatitis b virus core antigen protein and an epitope of claudin 18.2 |
| EP2366709A1 (en) * | 2010-03-16 | 2011-09-21 | BioNTech AG | Tumor vaccination involving a humoral immune response against self-proteins |
| US9493528B2 (en) * | 2013-01-10 | 2016-11-15 | Supadelixir Inc. | Microphthalmia-associated transcription factor-derived peptide and composition containing same |
| WO2018044858A2 (en) * | 2016-08-29 | 2018-03-08 | The Cleveland Clinic Foundation | C5 immunization for autologous anti-c5 antibody production |
| CN113461786B (zh) * | 2020-03-30 | 2022-09-13 | 普莱柯生物工程股份有限公司 | 一种禽流感病毒样颗粒疫苗、及其制备方法和应用 |
| CN120193015A (zh) * | 2025-05-26 | 2025-06-24 | 中国热带农业科学院三亚研究院 | 木薯普通花叶病毒TGBp1在下调MeGRXC3上的应用 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6042832A (en) * | 1996-08-28 | 2000-03-28 | Thomas Jefferson University | Polypeptides fused with alfalfa mosaic virus or ilarvirus capsid proteins |
| IT1317046B1 (it) * | 2000-06-16 | 2003-05-26 | Ist Superiore Sanita | Proteina di fusione, particelle virali chimeriche che la espongono sulcapside, piante infettate con tali particelle, loro usi e composizioni |
| CA2434000C (en) * | 2002-07-05 | 2012-07-17 | Denis Leclerc | Adjuvant viral particle |
| US8101189B2 (en) * | 2002-07-05 | 2012-01-24 | Folia Biotech Inc. | Vaccines and immunopotentiating compositions and methods for making and using them |
-
2008
- 2008-09-11 JP JP2010524318A patent/JP2010538619A/ja active Pending
- 2008-09-11 WO PCT/CA2008/001603 patent/WO2009033276A1/en not_active Ceased
- 2008-09-11 CA CA2699093A patent/CA2699093A1/en not_active Abandoned
- 2008-09-11 EP EP08800307A patent/EP2201106A4/en not_active Withdrawn
- 2008-09-11 US US12/677,772 patent/US20110104191A1/en not_active Abandoned
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