EA201890560A1 - Новые пептиды, комбинации пептидов и каркасы для применения в иммунотерапевтическом методе лечения различных видов рака - Google Patents

Новые пептиды, комбинации пептидов и каркасы для применения в иммунотерапевтическом методе лечения различных видов рака

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EA201890560A1
EA201890560A1 EA201890560A EA201890560A EA201890560A1 EA 201890560 A1 EA201890560 A1 EA 201890560A1 EA 201890560 A EA201890560 A EA 201890560A EA 201890560 A EA201890560 A EA 201890560A EA 201890560 A1 EA201890560 A1 EA 201890560A1
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peptides
framework
application
present
cancer types
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EA201890560A
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Андреа Мар
Тони Вайншенк
Оливер Шоор
Йенс Фритше
Харприт Сингх
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Имматикс Биотекнолоджис Гмбх
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Publication of EA201890560A1 publication Critical patent/EA201890560A1/ru

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Abstract

Настоящее изобретение относится к пептидам, белкам, нуклеиновым кислотам и клеткам для применения в иммунотерапевтических методах. В частности, настоящее изобретение относится к иммунотерапии рака. Настоящее изобретение относится далее к опухолеассоциированным пептидным эпитопам T-клеток, в отдельности или в комбинации с другими опухолеассоциированными пептидами, которые могут, например, служить в качестве активных фармацевтических ингредиентов вакцинных композиций, стимулирующих противоопухолевые иммунные ответы, или стимулировать T-клетки ex vivo с их перенесением в организм пациента. Пептиды, связанные с молекулами главного комплекса гистосовместимости (МНС), или пептиды в отдельности могут быть также мишенями антител, растворимых T-клеточных рецепторов и других связывающих молекул.
EA201890560A 2015-08-28 2016-08-26 Новые пептиды, комбинации пептидов и каркасы для применения в иммунотерапевтическом методе лечения различных видов рака EA201890560A1 (ru)

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US201562211276P 2015-08-28 2015-08-28
GBGB1515321.6A GB201515321D0 (en) 2015-08-28 2015-08-28 Novel peptides, combination of peptides and scaffolds for use in immunotherapeutic treatment of various cancers
PCT/EP2016/070146 WO2017036936A1 (en) 2015-08-28 2016-08-26 Novel peptides, combination of peptides and scaffolds for use in immunotherapeutic treatment of various cancers

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EA201891874A EA201891874A3 (ru) 2015-08-28 2016-08-26 Новые пептиды, комбинации пептидов и каркасы для применения в иммунотерапевтическом методе лечения различных видов рака

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CN (1) CN107921111B (ru)
AU (3) AU2016313684B2 (ru)
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GB201507030D0 (en) 2015-04-24 2015-06-10 Immatics Biotechnologies Gmbh Immunotherapy against lung cancers, in particular NSCLC
GB201515321D0 (en) * 2015-08-28 2015-10-14 Immatics Biotechnologies Gmbh Novel peptides, combination of peptides and scaffolds for use in immunotherapeutic treatment of various cancers
CN108601731A (zh) 2015-12-16 2018-09-28 磨石肿瘤生物技术公司 新抗原的鉴别、制造及使用
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