EA201891874A3 - Новые пептиды, комбинации пептидов и каркасы для применения в иммунотерапевтическом методе лечения различных видов рака - Google Patents

Новые пептиды, комбинации пептидов и каркасы для применения в иммунотерапевтическом методе лечения различных видов рака

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EA201891874A3
EA201891874A3 EA201891874A EA201891874A EA201891874A3 EA 201891874 A3 EA201891874 A3 EA 201891874A3 EA 201891874 A EA201891874 A EA 201891874A EA 201891874 A EA201891874 A EA 201891874A EA 201891874 A3 EA201891874 A3 EA 201891874A3
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Prior art keywords
peptides
framework
application
present
cancer types
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EA201891874A
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English (en)
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EA201891874A2 (ru
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Андреа Мар
Тони Вайншенк
Оливер Шоор
Йенс Фритше
Харприт Сингх
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Имматикс Биотекнолоджис Гмбх
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Publication of EA201891874A2 publication Critical patent/EA201891874A2/ru
Publication of EA201891874A3 publication Critical patent/EA201891874A3/ru

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    • A—HUMAN NECESSITIES
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    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
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    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
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Abstract

Настоящее изобретение относится к пептидам, белкам, нуклеиновым кислотам и клеткам для применения в иммунотерапевтических методах. В частности, настоящее изобретение относится к иммунотерапии рака. Настоящее изобретение относится далее к опухолеассоциированным пептидным эпитопам T-клеток, в отдельности или в комбинации с другими опухолеассоциированными пептидами, которые могут, например, служить в качестве активных фармацевтических ингредиентов вакцинных композиций, стимулирующих противоопухолевые иммунные ответы, или стимулировать T-клетки ex vivo с их перенесением в организм пациента. Пептиды, связанные с молекулами главного комплекса гистосовместимости (MHC), или пептиды в отдельности могут быть также мишенями антител, растворимых T-клеточных рецепторов и других связывающих молекул.
EA201891874A 2015-08-28 2016-08-26 Новые пептиды, комбинации пептидов и каркасы для применения в иммунотерапевтическом методе лечения различных видов рака EA201891874A3 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562211276P 2015-08-28 2015-08-28
GBGB1515321.6A GB201515321D0 (en) 2015-08-28 2015-08-28 Novel peptides, combination of peptides and scaffolds for use in immunotherapeutic treatment of various cancers

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EA201891874A2 EA201891874A2 (ru) 2019-01-31
EA201891874A3 true EA201891874A3 (ru) 2019-05-31

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EA201891874A EA201891874A3 (ru) 2015-08-28 2016-08-26 Новые пептиды, комбинации пептидов и каркасы для применения в иммунотерапевтическом методе лечения различных видов рака
EA201890560A EA201890560A1 (ru) 2015-08-28 2016-08-26 Новые пептиды, комбинации пептидов и каркасы для применения в иммунотерапевтическом методе лечения различных видов рака

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US (7) US10576132B2 (ru)
EP (2) EP3341014A1 (ru)
JP (1) JP6970974B2 (ru)
KR (3) KR20180038550A (ru)
CN (1) CN107921111B (ru)
AU (3) AU2016313684B2 (ru)
BR (1) BR112018003460A2 (ru)
CA (2) CA3072922A1 (ru)
CR (6) CR20200493A (ru)
EA (2) EA201891874A3 (ru)
GB (1) GB201515321D0 (ru)
MA (7) MA43457A1 (ru)
MX (1) MX2018002480A (ru)
PE (2) PE20181164A1 (ru)
SG (3) SG10202001830PA (ru)
TW (15) TWI699377B (ru)
UA (1) UA124577C2 (ru)
WO (1) WO2017036936A1 (ru)

Families Citing this family (24)

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Publication number Priority date Publication date Assignee Title
GB201507030D0 (en) 2015-04-24 2015-06-10 Immatics Biotechnologies Gmbh Immunotherapy against lung cancers, in particular NSCLC
TWI765875B (zh) 2015-12-16 2022-06-01 美商磨石生物公司 新抗原辨識、製造及用途
JP7075125B2 (ja) 2016-05-25 2022-05-25 イマティクス バイオテクノロジーズ ゲーエムベーハー 標的としてのおよび胆嚢がんおよび胆管がんおよびその他のがんに対する免疫療法で使用するための新規ペプチド、ペプチド組み合わせ
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