JP2018507861A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2018507861A5 JP2018507861A5 JP2017544878A JP2017544878A JP2018507861A5 JP 2018507861 A5 JP2018507861 A5 JP 2018507861A5 JP 2017544878 A JP2017544878 A JP 2017544878A JP 2017544878 A JP2017544878 A JP 2017544878A JP 2018507861 A5 JP2018507861 A5 JP 2018507861A5
- Authority
- JP
- Japan
- Prior art keywords
- optionally substituted
- pharmaceutically acceptable
- acceptable salt
- compound according
- alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 0 C*C1CCNCC1 Chemical compound C*C1CCNCC1 0.000 description 3
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562120671P | 2015-02-25 | 2015-02-25 | |
| US62/120,671 | 2015-02-25 | ||
| US201562200483P | 2015-08-03 | 2015-08-03 | |
| US62/200,483 | 2015-08-03 | ||
| PCT/US2016/019393 WO2016138158A1 (en) | 2015-02-25 | 2016-02-24 | Antiviral compounds |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018507861A JP2018507861A (ja) | 2018-03-22 |
| JP2018507861A5 true JP2018507861A5 (https=) | 2019-04-25 |
| JP6716587B2 JP6716587B2 (ja) | 2020-07-01 |
Family
ID=56689780
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017544878A Expired - Fee Related JP6716587B2 (ja) | 2015-02-25 | 2016-02-24 | 抗ウイルス化合物 |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US10358453B2 (https=) |
| EP (1) | EP3262048A4 (https=) |
| JP (1) | JP6716587B2 (https=) |
| KR (2) | KR20210028752A (https=) |
| CN (1) | CN107922427B (https=) |
| AU (1) | AU2016222729B2 (https=) |
| BR (1) | BR112017018022A2 (https=) |
| CA (1) | CA2977150A1 (https=) |
| EA (1) | EA038732B1 (https=) |
| IL (1) | IL254011B (https=) |
| MA (1) | MA41614A (https=) |
| MX (1) | MX385571B (https=) |
| PH (1) | PH12017501534A1 (https=) |
| TW (1) | TWI704135B (https=) |
| UA (1) | UA123393C2 (https=) |
| WO (1) | WO2016138158A1 (https=) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2013305759C1 (en) | 2012-08-23 | 2018-01-18 | Janssen Biopharma, Inc. | Compounds for the treatment of paramoxyvirus viral infections |
| GEP201706757B (en) | 2012-12-21 | 2017-10-25 | Alios Biopharma Inc | Substituted nucleosides, nucleotides and analogs thereof |
| NZ716822A (en) | 2013-08-21 | 2017-10-27 | Alios Biopharma Inc | Antiviral compounds |
| MY197231A (en) | 2015-07-22 | 2023-06-06 | Enanta Pharm Inc | Benzodiazepine derivatives as rsv inhibitors |
| KR102627756B1 (ko) * | 2017-03-22 | 2024-01-23 | 쑤저우 바이지부공 파마수티컬 테크널러지 컴퍼니 리미티드 | 브루톤 타이로신 키나제 억제제 |
| WO2018222774A1 (en) * | 2017-05-30 | 2018-12-06 | Alios Biopharma, Inc. | Methods for treating pneumoviruses |
| WO2019006295A1 (en) | 2017-06-30 | 2019-01-03 | Enanta Pharmaceuticals, Inc. | HETEROCYCLIC COMPOUNDS AS RSV INHIBITORS |
| CA3077309A1 (en) | 2017-09-29 | 2019-04-04 | Enanta Pharmaceuticals, Inc. | Combination pharmaceutical agents as rsv inhibitors |
| WO2020048828A1 (en) | 2018-09-03 | 2020-03-12 | Bayer Pharma Aktiengesellschaft | 5-heteroaryl-3,9-diazaspiro[5.5]undecane compounds |
| WO2020048827A1 (en) | 2018-09-03 | 2020-03-12 | Bayer Aktiengesellschaft | 1, 3, 9-triazaspiro[5.5] undecan-2-one compounds |
| CN109280027A (zh) * | 2018-12-13 | 2019-01-29 | 康化（上海）新药研发有限公司 | 一种5,6-二甲氧基-2-吡啶甲酸的合成方法 |
| KR102926658B1 (ko) | 2019-03-18 | 2026-02-11 | 이난타 파마슈티칼스, 인코포레이티드 | Rsv 억제제로서의 벤조디아제핀 유도체 |
| AU2020357452B2 (en) * | 2019-10-04 | 2026-01-29 | Enanta Pharmaceuticals, Inc | Antiviral heterocyclic compounds |
| US11505558B1 (en) | 2019-10-04 | 2022-11-22 | Enanta Pharmaceuticals, Inc. | Antiviral heterocyclic compounds |
| UY39032A (es) | 2020-01-24 | 2021-07-30 | Enanta Pharm Inc | Compuestos heterocíclicos como agentes antivirales |
| EP4107151A1 (en) | 2020-02-18 | 2022-12-28 | Bayer Aktiengesellschaft | Heteroaryl-triazole compounds as pesticides |
| WO2021198981A1 (en) | 2020-04-01 | 2021-10-07 | Janssen Biopharma, Inc. | Antiviral compounds and uses thereof |
| JP2023522091A (ja) * | 2020-04-21 | 2023-05-26 | ヤンセン・サイエンシズ・アイルランド・アンリミテッド・カンパニー | Ｒｓｖ阻害性の３置換キノリン及びシンノリン誘導体 |
| US11534439B2 (en) | 2020-07-07 | 2022-12-27 | Enanta Pharmaceuticals, Inc. | Dihydroquinoxaline and dihydropyridopyrazine derivatives as RSV inhibitors |
| US11945824B2 (en) | 2020-10-19 | 2024-04-02 | Enanta Pharmaceuticals, Inc. | Heterocyclic compounds as anti-viral agents |
| CN116528850B (zh) | 2020-10-28 | 2025-08-22 | 盐野义制药株式会社 | 具有抗病毒活性的酰胺衍生物 |
| CN117043166A (zh) * | 2021-02-26 | 2023-11-10 | 英安塔制药有限公司 | 抗病毒杂环化合物 |
| IL305189A (en) | 2021-02-26 | 2023-10-01 | Enanta Pharm Inc | Heterocyclic antiviral compounds |
| WO2022211812A1 (en) * | 2021-04-01 | 2022-10-06 | Enanta Pharmaceuticals, Inc. | Antiviral heterocyclic compounds |
| WO2023052593A1 (en) | 2021-10-01 | 2023-04-06 | Janssen Sciences Ireland Unlimited Company | Rsv inhibiting spiro bearing derivatives |
| AR129003A1 (es) * | 2022-04-07 | 2024-07-03 | Enanta Pharm Inc | Compuestos heterocíclicos antivirales |
| US12162857B2 (en) | 2022-04-27 | 2024-12-10 | Enanta Pharmaceuticals, Inc. | Antiviral compounds |
| WO2023237730A1 (en) | 2022-06-10 | 2023-12-14 | Janssen Sciences Ireland Unlimited Company | Rsv inhibiting triazolo and spiro bearing derivatives |
| WO2023237732A1 (en) | 2022-06-10 | 2023-12-14 | Janssen Sciences Ireland Unlimited Company | Rsv inhibiting triazolo bearing derivatives |
| CN115785080B (zh) * | 2022-12-16 | 2024-10-11 | 陕西盘龙药业集团股份有限公司 | 一种尿嘧啶母核类化合物及其制备方法和应用 |
| TW202521519A (zh) * | 2023-08-17 | 2025-06-01 | 美商默沙東有限責任公司 | 人類呼吸道融合病毒及間質肺病毒抑制劑 |
| US11964954B1 (en) | 2023-08-29 | 2024-04-23 | King Faisal University | N'-[(2-chlorobenzoyl)oxy]-1,3-benzothiazole-2-carboximidamide as an antitumor and antimicrobial compound |
| US11912697B1 (en) | 2023-08-29 | 2024-02-27 | King Faisal University | 1,3-benzothiazol-2-yl-N′-[(pyridine-3-carbonyl)oxy]ethanimidamide as an antitumor and antimicrobial compound |
| CN119161297A (zh) * | 2024-09-18 | 2024-12-20 | 浙江工业大学 | 一种4-溴-6-氯烟酸甲酯的制备方法 |
Family Cites Families (60)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MA26487A1 (fr) | 1997-04-29 | 2004-12-20 | Smithkline Beecham Corp | Heterocyclecetohydrazides inhibiteurs de proteases, procede pour leur preparation et compositions pharmaceutiques les contenant . |
| CN1548436A (zh) | 1998-05-22 | 2004-11-24 | ʷ��˿�������ȳ�ķ����˾ | 新的2-烷基取代咪唑化合物 |
| AR018915A1 (es) | 1998-06-24 | 2001-12-12 | Smithkline Beecham Corp | Inhibidores de proteasas diacilhidrazinicos, composicion farmaceutica que la comprenden, usos de los mismos para la manufactura de un medicamento, unprocedimiento de fabricacion de dichos compuestos |
| US6623741B1 (en) | 2000-02-29 | 2003-09-23 | Trimeris, Inc. | Methods and compositions for inhibition of membrane fusion-associated events including RSV transmission |
| US6878743B2 (en) | 2001-09-18 | 2005-04-12 | Sunesis Pharmaceuticals, Inc. | Small molecule inhibitors of caspases |
| CA2462112A1 (en) | 2001-10-01 | 2003-04-10 | Bristol-Myers Squibb Company | Spiro-hydantoin compounds useful as anti-inflammatory agents |
| US20040071757A1 (en) * | 2001-11-20 | 2004-04-15 | David Rolf | Inhalation antiviral patch |
| EP1456165A1 (en) | 2001-11-30 | 2004-09-15 | The Burnham Institute | Induction of apoptosis in cancer cells |
| BR0314595A (pt) * | 2002-09-20 | 2005-08-09 | Arrow Therapeutics Ltd | Uso de um derivado de benzodiazepina ou um sal farmaceuticamente aceitável deste, inalador ou nebulisador, produto, usos de um produto e de um composto ou sal farmaceuticamente aceitável deste, derivado de benzodiazepina, composto, e, composição farmacêutica |
| JP4449389B2 (ja) | 2003-09-26 | 2010-04-14 | パナソニック株式会社 | プラズマディスプレイ装置用蛍光体の製造方法 |
| DE10348023A1 (de) | 2003-10-15 | 2005-05-19 | Imtm Gmbh | Neue Alanyl-Aminopeptidasen-Inhibitoren zur funktionellen Beeinflussung unterschiedlicher Zellen und zur Behandlung immunologischer, entzündlicher, neuronaler und anderer Erkrankungen |
| WO2005042530A1 (en) | 2003-10-30 | 2005-05-12 | Boehringer Ingelheim (Canada) Ltd. | Rsv polymerase inhibitors |
| WO2005048945A2 (en) * | 2003-11-14 | 2005-06-02 | 3M Innovative Properties Company | Hydroxylamine substituted imidazo ring compounds |
| ATE501135T1 (de) * | 2003-12-18 | 2011-03-15 | Tibotec Pharm Ltd | Piperidinamino-benzimidazol-derivate al respiratorisches syncytialvirus replikation inhibitoren |
| EP1697343B1 (en) | 2003-12-18 | 2009-07-01 | Tibotec Pharmaceuticals Ltd. | Aminobenzimidazoles and benzimidazoles as inhibitors of respiratory syncytial virus replication |
| JP2007519735A (ja) | 2004-01-30 | 2007-07-19 | メルク エンド カムパニー インコーポレーテッド | Ｈｉｖインテグラーゼ阻害剤として有用であるｎ−ベンジル−３，４−ジヒドロキシピリジン−２−カルボキサミド及びｎ−ベンジル−２，３−ジヒドロキシピリジン−４−カルボキサミド化合物 |
| GB0406280D0 (en) | 2004-03-19 | 2004-04-21 | Arrow Therapeutics Ltd | Chemical compounds |
| DE102005024245A1 (de) * | 2005-05-27 | 2006-11-30 | Merck Patent Gmbh | Thienopyridine |
| CA2612263C (en) | 2005-06-20 | 2015-04-14 | Tibotec Pharmaceuticals Ltd. | 1-(2-amino-3-(substituted alkyl)-3h-benzimidazolylmethyl)-3-subtituted-1,3-dihydro-benzoimidazol-2-ones with activity on respiratory syncytial virus |
| US7572810B2 (en) | 2006-06-08 | 2009-08-11 | Bristol-Myers Squibb Company | Alkene piperidine derivatives as antiviral agents |
| AU2008334948B2 (en) | 2007-12-13 | 2014-11-20 | Alnylam Pharmaceuticals, Inc. | Methods and compositions for prevention or treatment of RSV infection |
| EP2719700A1 (en) | 2008-01-09 | 2014-04-16 | Amura Therapeutics Limited | Tetrahydrofuro(3,2-b)pyrrol-3-one derivatives as inhibitors of cysteine proteinases |
| US20110105436A1 (en) | 2008-03-10 | 2011-05-05 | Auckland Uniservices Limited | Heteroaryl compounds, compositions, and methods of use in cancer treatment |
| US9173706B2 (en) | 2008-08-25 | 2015-11-03 | Covidien Lp | Dual-band dipole microwave ablation antenna |
| AU2009314205A1 (en) | 2008-11-13 | 2010-05-20 | Merck Sharp & Dohme Corp. | Gamma secretase modulators |
| US20100184815A1 (en) | 2008-12-19 | 2010-07-22 | Luehr Gary W | Agonists of peroxisome proliferator activated receptor-alpha |
| WO2010103306A1 (en) | 2009-03-10 | 2010-09-16 | Astrazeneca Uk Limited | Benzimidazole derivatives and their use as antivaral agents |
| US20110033393A1 (en) | 2009-05-12 | 2011-02-10 | Stein Philip | Hydrazone Compounds and Their Use |
| WO2010132992A1 (en) | 2009-05-20 | 2010-11-25 | UNIVERSITé LAVAL | Compounds for the inhibition of herpesviruses |
| MX373926B (es) * | 2009-05-27 | 2020-07-10 | Ptc Therapeutics Inc | Metodos para tratar cancer y estados no neoplasicos. |
| ES2643034T3 (es) | 2009-06-05 | 2017-11-21 | Ablynx N.V. | Construcciones de Nanobody contra el virus respiratorio sincicial humano (VRSH) trivalentes para la prevención y/o el tratamiento de infecciones de las vías respiratorias |
| BR112012000657A2 (pt) | 2009-06-26 | 2016-11-16 | Panacea Biotec Ltd | novos azabicilohexanos |
| WO2011005842A1 (en) | 2009-07-09 | 2011-01-13 | Gilead Sciences, Inc. | Anti-rsv compounds |
| AR078793A1 (es) * | 2009-10-27 | 2011-12-07 | Orion Corp | Derivados de carboxamidas no esteroidales y acil hidrazona moduladores de receptores androgenicos de tejido selectivo (sarm), composiciones farmaceuticas que los contienen y uso de los mismos en el tratamiento del cancer de prostata entre otros |
| WO2011097607A1 (en) | 2010-02-08 | 2011-08-11 | Southern Research Institute | Anti-viral treatment and assay to screen for anti-viral agent |
| GB201010193D0 (en) * | 2010-06-17 | 2010-07-21 | Respivert Ltd | Medicinal use |
| MA34392B1 (fr) | 2010-06-24 | 2013-07-03 | Gilead Sciences Inc | Pyrimidines en tant qu'agents antiviraux |
| US8796303B2 (en) | 2010-11-26 | 2014-08-05 | Biota Scientific Management Pty Ltd. | Imidazo[2,1-G][1,7]naphthyridines for treating respiratory syncytial virus infections |
| TWI530495B (zh) | 2010-12-16 | 2016-04-21 | 健生科學愛爾蘭無限公司 | 苯并咪唑呼吸道融合病毒抑制劑 |
| TWI527814B (zh) | 2010-12-16 | 2016-04-01 | 健生科學愛爾蘭無限公司 | 作為呼吸道融合病毒抗病毒劑之氮雜苯并咪唑類 |
| TWI515187B (zh) | 2010-12-16 | 2016-01-01 | 健生科學愛爾蘭無限公司 | 作為呼吸道融合病毒抗病毒劑之吲哚類 |
| TWI541241B (zh) | 2010-12-16 | 2016-07-11 | 健生科學愛爾蘭無限公司 | 作為呼吸道融合病毒抗病毒劑之咪唑并吡啶類 |
| TWI501967B (zh) | 2010-12-16 | 2015-10-01 | Janssen R&D Ireland | 作為呼吸道融合病毒抗病毒劑之氮雜吲哚類 |
| EP2548877A1 (en) | 2011-07-19 | 2013-01-23 | MSD Oss B.V. | 4-(5-Membered fused pyridinyl)benzamides as BTK-inhibitors |
| WO2013020164A1 (en) * | 2011-08-05 | 2013-02-14 | Biota Scientific Management Pty Ltd | Compounds for treating respiratory syncytial virus infections |
| WO2013041457A1 (en) | 2011-09-22 | 2013-03-28 | Msd Oss B.V. | N-piperidin-4-yl derivatives |
| EP2766370B1 (en) | 2011-10-11 | 2016-08-03 | F.Hoffmann-La Roche Ag | Compounds for the treatment and prophylaxis of respiratory syncytial virus disease |
| WO2013059119A1 (en) | 2011-10-17 | 2013-04-25 | The Regents Of The University Of Michigan | Glucosylceramide synthase inhibitors and therapeutic methods using the same |
| US20140287916A1 (en) | 2011-11-04 | 2014-09-25 | Syngenta Participations Ag | Pesticidal compounds |
| ES2668841T3 (es) | 2011-11-29 | 2018-05-22 | Vivozon Inc. | Derivado novedoso de benzamida y uso del mismo |
| CA2858096C (en) | 2011-12-22 | 2020-06-23 | Gilead Sciences, Inc. | Pyrazolo[1,5-a]pyrimidines as antiviral agents |
| CN106986869A (zh) | 2012-04-17 | 2017-07-28 | 吉利德科学公司 | 用于抗病毒治疗的化合物和方法 |
| WO2013186334A1 (en) | 2012-06-15 | 2013-12-19 | Janssen R&D Ireland | 1,3-dihydro-2h-benzimidazol-2-one derivatives substituted with benzimidazoles as respiratory syncytial virus antiviral agents |
| LT2864323T (lt) | 2012-06-15 | 2017-07-25 | Janssen Sciences Ireland Uc | 1,3-dihidro-2h-benzimidazol-2-ono dariniai, turintys heterociklų pakaitų, kaip antivirusiniai agentai prieš respiratorinį sincitinį virusą |
| EA201590023A1 (ru) | 2012-06-15 | 2015-05-29 | ЯНССЕН Ар ЭНД Ди АЙРЛЭНД | Новые 4-замещенные производные 1,3-дигидро-2h-бензимидазол-2-она, замещенные бензимидазолами, в качестве противовирусных средств против респираторного синцитиального вируса |
| KR20150032283A (ko) | 2012-06-15 | 2015-03-25 | 얀센 알 앤드 디 아일랜드 | 호흡기 합포체 바이러스의 항바이러스제로서의 헤테로사이클로 치환된 1,3-디하이드로-2h-벤즈이미다졸-2-온 유도체 |
| RU2015102792A (ru) | 2012-07-10 | 2016-08-27 | Ф. Хоффманн-Ля Рош Аг | Новые индазолы для лечения и профилактики респираторно-синцитиальной вирусной инфекции |
| AU2013305759C1 (en) | 2012-08-23 | 2018-01-18 | Janssen Biopharma, Inc. | Compounds for the treatment of paramoxyvirus viral infections |
| NZ716822A (en) | 2013-08-21 | 2017-10-27 | Alios Biopharma Inc | Antiviral compounds |
| EP3290407B1 (en) | 2013-10-18 | 2020-01-01 | Celgene Quanticel Research, Inc | Bromodomain inhibitors |
-
2016
- 2016-02-23 MA MA041614A patent/MA41614A/fr unknown
- 2016-02-24 KR KR1020217006854A patent/KR20210028752A/ko not_active Ceased
- 2016-02-24 KR KR1020177026450A patent/KR20170122775A/ko not_active Withdrawn
- 2016-02-24 US US15/052,631 patent/US10358453B2/en active Active
- 2016-02-24 CN CN201680024046.4A patent/CN107922427B/zh not_active Expired - Fee Related
- 2016-02-24 EA EA201791886A patent/EA038732B1/ru unknown
- 2016-02-24 AU AU2016222729A patent/AU2016222729B2/en not_active Ceased
- 2016-02-24 BR BR112017018022-7A patent/BR112017018022A2/pt not_active IP Right Cessation
- 2016-02-24 UA UAA201709269A patent/UA123393C2/uk unknown
- 2016-02-24 WO PCT/US2016/019393 patent/WO2016138158A1/en not_active Ceased
- 2016-02-24 JP JP2017544878A patent/JP6716587B2/ja not_active Expired - Fee Related
- 2016-02-24 CA CA2977150A patent/CA2977150A1/en active Pending
- 2016-02-24 EP EP16756295.8A patent/EP3262048A4/en not_active Withdrawn
- 2016-02-24 MX MX2017010933A patent/MX385571B/es unknown
- 2016-02-25 TW TW105105765A patent/TWI704135B/zh not_active IP Right Cessation
-
2017
- 2017-08-15 IL IL254011A patent/IL254011B/en unknown
- 2017-08-24 PH PH12017501534A patent/PH12017501534A1/en unknown
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2018507861A5 (https=) | ||
| JP2016538316A5 (https=) | ||
| US11479551B2 (en) | MTA-cooperative PRMT5 inhibitors | |
| US10766902B2 (en) | Wee-1 inhibiting pyrazolopyrimidinone compounds | |
| ES2778700T3 (es) | Nuevos derivados de piperidinilo sustituidos con (hetero)arilo, un proceso para su preparación y composiciones farmacéuticas que los contienen | |
| RU2017106742A (ru) | Комбинированная терапия для лечения парамиксовируса | |
| HRP20231730T1 (hr) | Fenilaminopirimidin amidni inhibitori autofagije i postupci njihove primjene | |
| JP6716587B2 (ja) | 抗ウイルス化合物 | |
| US20240208912A1 (en) | MTA-Cooperative PRMT5 Inhibitors | |
| AU2021370660A1 (en) | Heterocyclic spiro compounds and methods of use | |
| ES2271221T3 (es) | Derivados imidazo-pirimidina como ligandos para receptores gaba. | |
| JP2011507854A5 (https=) | ||
| RU2019120986A (ru) | Фармацевтическая комбинация, содержащая ингибитор alk и ингибитор shp2 | |
| JP2014511355A5 (https=) | ||
| JP2016500073A5 (https=) | ||
| JP2014506929A5 (https=) | ||
| HRP20151398T1 (hr) | Tricikliäśni derivati amina kao inhibitori protein tirozin kinaze | |
| JP2017535536A5 (https=) | ||
| JP2009538896A5 (https=) | ||
| JP2015511245A5 (https=) | ||
| JP2012501312A5 (https=) | ||
| AU2012230890A1 (en) | Azole compounds as Pim inhibitors | |
| RU2007128625A (ru) | Гетероциклические замещенные фенилметаноны в качестве ингибиторов переносчика глицина 1 | |
| RS54788B1 (sr) | Inhibitori pirimidina pde10 | |
| HRP20121022T1 (hr) | Kondenzirani bicikliäśki pirimidini |