|
DE2557425C2
(de)
|
1975-12-19 |
1987-03-19 |
C.H. Boehringer Sohn, 6507 Ingelheim |
11-Oxo-11-H-pyrido[2,1-b]-chinazolin-2-carbonsäure und ihre Salze, Verfahren zu ihrer Herstellung und Arzneimittel
|
|
DE3704203A1
(de)
|
1987-02-11 |
1988-08-25 |
Boehringer Ingelheim Kg |
Verwendung von oxochinazolinderivaten bei der behandlung der hyperurikaemie
|
|
US5244911A
(en)
|
1991-03-28 |
1993-09-14 |
Eli Lilly And Company |
6-heterocyclic-4-amino-1,2,2a,3,4,5-hexahydrobenz(cd)indoles and pharmaceutical use thereof
|
|
US5153185A
(en)
|
1991-04-16 |
1992-10-06 |
Merck & Co., Inc. |
2-phenanthridonyl carbapenems
|
|
US5294610A
(en)
|
1992-10-15 |
1994-03-15 |
Merck & Co. Inc. |
2-(aza-9-fluorenonyl)carbapenem antibacterial agents
|
|
US5262564A
(en)
|
1992-10-30 |
1993-11-16 |
Octamer, Inc. |
Sulfinic acid adducts of organo nitroso compounds useful as retroviral inactivating agents anti-retroviral agents and anti-tumor agents
|
|
EP0638071B1
(en)
|
1992-12-28 |
1997-04-09 |
Eisai Co., Ltd. |
Heterocyclic carbonic acid derivatives which bind to retinoid receptors (rar)
|
|
WO1994015608A1
(en)
|
1993-01-15 |
1994-07-21 |
Agouron Pharmaceuticals, Inc. |
Hiv protease inhibitors
|
|
US5384317A
(en)
|
1993-08-02 |
1995-01-24 |
Merck & Co., Inc. |
Bridged biphenyl carbapenem compounds, compositions containing such compounds and methods of use
|
|
AU704114B2
(en)
|
1993-11-18 |
1999-04-15 |
Siga Technologies, Inc. |
Compounds and pharmaceutical compositions for the treatment and prophylaxis of bacterial infections
|
|
US6872542B1
(en)
|
1993-11-18 |
2005-03-29 |
Siga Pharmaceuticals, Inc. |
Treatment or prophylaxis of diseases caused by pilus-forming bacteria
|
|
US6420127B1
(en)
|
1994-11-18 |
2002-07-16 |
Washington University |
Compounds and pharmaceutical compositions for the treatment and prophylaxis of bacterial infections
|
|
US6110913A
(en)
|
1994-01-04 |
2000-08-29 |
Novo Nordisk A/S |
N-substituted azaheterocyclic carboxylic acids and esters thereof
|
|
US5532261A
(en)
|
1994-12-12 |
1996-07-02 |
Merck & Co., Inc. |
Carbapenem antibiotics, compositions containing such compounds and methods of use
|
|
US5719144A
(en)
|
1995-02-22 |
1998-02-17 |
Merck & Co., Inc. |
Fibrinogen receptor antagonists
|
|
BR9606547A
(pt)
|
1995-08-02 |
1997-10-14 |
Uriach & Cia Sa J |
Novos derivados de pirimidona com atividade fungicida
|
|
US5728844A
(en)
|
1995-08-29 |
1998-03-17 |
Celgene Corporation |
Immunotherapeutic agents
|
|
WO1997048786A1
(de)
|
1996-06-19 |
1997-12-24 |
Call Hans Peter |
Mehrkomponentensystem zur verwendung mit waschaktiven substanzen
|
|
US6566384B1
(en)
|
1996-08-07 |
2003-05-20 |
Darwin Discovery Ltd. |
Hydroxamic and carboxylic acid derivatives having MMP and TNF inhibitory activity
|
|
DE19726241A1
(de)
|
1997-06-20 |
1998-12-24 |
Call Krimhild |
Erweitertes enzymatisches Multikomponentensystem zur Behandlung von Abwässern, zur Herstellung von Holzverbundstoffen, zum Deinken von Altpapier, Colour stripping von Altpapier, zum Einsatz als Oxidationssystem bei der organischen Synthese und zum Einsatz bei der Kohleverflüssigung
|
|
IL121748A0
(en)
|
1997-09-11 |
1998-02-22 |
Yeda Res & Dev |
Vanadium complexes of hydroxamates and pharmaceutical compositions comprising them
|
|
US6403632B1
(en)
|
2000-03-01 |
2002-06-11 |
Bristol Myers Squibb Pharma Co |
Lactam metalloprotease inhibitors
|
|
US6180640B1
(en)
|
1998-06-25 |
2001-01-30 |
Sepracor, Inc. |
Di- and tetra-hydroquinoline-indole antimicrobial agents, uses and compositions related thereto
|
|
JP2000044562A
(ja)
|
1998-07-31 |
2000-02-15 |
Kyowa Hakko Kogyo Co Ltd |
ピロロフタルイミド誘導体
|
|
CA2350590A1
(en)
|
1998-12-04 |
2000-06-15 |
John A. Butera |
Substituted benzofuranoindoles and indenoindoles as novel potassium channel openers
|
|
US6288099B1
(en)
|
1998-12-04 |
2001-09-11 |
American Home Products Corporation |
Substituted benzofuranoindoles and indenoindoles as novel potassium channel openers
|
|
US6946473B2
(en)
|
1999-01-27 |
2005-09-20 |
Wyeth Holdings Corporation |
Preparation and use of acetylenic ortho-sulfonamido and phosphinic acid amido bicyclic heteroaryl hydroxamic acids as TACE inhibitors
|
|
JP2000357809A
(ja)
|
1999-06-15 |
2000-12-26 |
Fuji Photo Film Co Ltd |
光電変換材料、光電変換素子及びポリメチン色素
|
|
JP4162106B2
(ja)
|
1999-06-17 |
2008-10-08 |
富士フイルム株式会社 |
光電変換素子および光電気化学電池ならびに金属錯体色素
|
|
WO2001012630A1
(en)
|
1999-08-13 |
2001-02-22 |
Sepracor Inc. |
Spirocyclic ligands for sigma receptors, and libraries and methods of use thereof
|
|
JP2001226269A
(ja)
|
2000-02-18 |
2001-08-21 |
Takeda Chem Ind Ltd |
メラニン凝集ホルモン拮抗剤
|
|
FR2809391B1
(fr)
|
2000-05-29 |
2003-05-09 |
Rhodia Chimie Sa |
Nouveau mortier phosphomagnesien, procede d'obtention de ce mortier
|
|
JP4340437B2
(ja)
|
2000-10-31 |
2009-10-07 |
レンセラール ポリテクニック インスティチュート |
8−カルボキサミド−2,6−メタノ−3−ベンズアゾシン
|
|
AU2002214222A1
(en)
|
2000-11-01 |
2002-05-15 |
Yeda Research And Development Co..Ltd. |
Pharmaceutical compositions comprising organic vanadium complexes for treatment of ischemia
|
|
EP1332131A2
(en)
|
2000-11-07 |
2003-08-06 |
Bristol-Myers Squibb Company |
Acid derivatives useful as serine protease inhibitors
|
|
US7214690B2
(en)
|
2001-02-23 |
2007-05-08 |
Ligand Pharmaceuticals Incorporated |
Tricyclic quinolinone and tricyclic quinoline androgen receptor modulator compounds and methods
|
|
IN192526B
(enExample)
|
2001-09-25 |
2004-04-24 |
Ranbaxy Lab |
|
|
FR2832711B1
(fr)
|
2001-11-26 |
2004-01-30 |
Warner Lambert Co |
Derives de triazolo [4,3-a] pyrido [2,3-d] pyrimidin-5-ones, compositions les contenant, procede de preparation et utilisation
|
|
TW200301698A
(en)
|
2001-12-21 |
2003-07-16 |
Bristol Myers Squibb Co |
Acridone inhibitors of IMPDH enzyme
|
|
CN100445276C
(zh)
|
2002-03-13 |
2008-12-24 |
詹森药业有限公司 |
用作组蛋白去乙酰酶抑制剂的磺酰基衍生物
|
|
WO2003087059A2
(en)
|
2002-04-08 |
2003-10-23 |
Sun Pharmaceutical Industries Limited |
(e)-oxime ether derivative of 5,6-dihydro-benzo[5,6]cyclohepta[1,2-b]pyridin-11-one
|
|
TW200404796A
(en)
|
2002-08-19 |
2004-04-01 |
Ono Pharmaceutical Co |
Nitrogen-containing compound
|
|
AU2003255845A1
(en)
|
2002-08-22 |
2004-03-11 |
Piramed Limited |
Phosphadidylinositol 3,5-biphosphate inhibitors as anti-viral agents
|
|
WO2004041285A1
(en)
|
2002-10-31 |
2004-05-21 |
Amgen Inc. |
Antiinflammation agents
|
|
JP2006510697A
(ja)
|
2002-12-20 |
2006-03-30 |
ビーエーエスエフ アクチェンゲゼルシャフト |
殺虫性ジベンゾ(ヘテロ)アゼピン誘導体
|
|
JP2004210716A
(ja)
|
2002-12-27 |
2004-07-29 |
Dai Ichi Seiyaku Co Ltd |
ジアミド誘導体
|
|
WO2004063156A1
(en)
|
2003-01-08 |
2004-07-29 |
Biovitrum Ab |
Novel indole derivates as fabp-4 inhibitors
|
|
US7704756B2
(en)
|
2003-01-21 |
2010-04-27 |
Novartis Vaccines And Diagnostics, Inc. |
Fluorogenic dyes
|
|
US7241775B2
(en)
|
2003-03-24 |
2007-07-10 |
Sanofi-Aventis Deutschland Gmbh |
Composition, process of making, and medical use of substituted 4-phenyltetrahydroisoquinolines
|
|
EP1622569B1
(en)
|
2003-04-24 |
2015-12-02 |
Incyte Corporation |
Aza spiro alkane derivatives as inhibitors of metallproteases
|
|
GB0313766D0
(en)
|
2003-06-13 |
2003-07-23 |
Xenova Ltd |
Pharmaceutical compounds
|
|
CA2537325A1
(en)
|
2003-09-19 |
2005-03-31 |
Gilead Sciences, Inc. |
Aza-quinolinol phosphonate integrase inhibitor compounds
|
|
CN101010298A
(zh)
*
|
2004-04-05 |
2007-08-01 |
默克Hdac研究有限责任公司 |
组蛋白脱乙酰酶抑制剂前药
|
|
US7705017B2
(en)
|
2004-05-03 |
2010-04-27 |
En Vivo Pharmaceuticals, Inc. |
Compounds for treatment of neurodegenerative diseases
|
|
WO2005111044A1
(en)
|
2004-05-17 |
2005-11-24 |
Tibotec Pharmaceuticals Ltd. |
4-substituted-1,5-dihydro-pyrido[3,2-b]indol-2-ones
|
|
AU2005251943A1
(en)
|
2004-06-09 |
2005-12-22 |
Altana Pharma Ag |
Substituted tricyclic benzimidazoles
|
|
WO2005123089A2
(en)
|
2004-06-10 |
2005-12-29 |
Kalypsys, Inc. |
Multicyclic sulfonamide compounds as inhibitors of histone deacetylase for the treatment of disease
|
|
AR051041A1
(es)
|
2004-10-04 |
2006-12-13 |
Altana Pharma Ag |
Bencimidazoles triciclicos condensados
|
|
UY29198A1
(es)
|
2004-11-09 |
2006-05-31 |
Cancer Rec Tech Ltd |
Derivados sustituidos de quinazolinona y derivados sustituidos de quinazolina-2, 4-diona, composiciones conteniéndolos, procedimientos de preparación y aplicaciones
|
|
WO2006065842A2
(en)
|
2004-12-13 |
2006-06-22 |
Synta Pharmaceuticals Corp. |
5,6,7,8-tetrahydroquinolines and related compounds and uses thereof
|
|
EP2298295B1
(en)
|
2005-01-31 |
2013-08-28 |
Cephalon, Inc. |
Tumor necrosis factor inhibitors
|
|
US8999289B2
(en)
|
2005-03-22 |
2015-04-07 |
President And Fellows Of Harvard College |
Treatment of protein degradation disorders
|
|
GB0509223D0
(en)
|
2005-05-05 |
2005-06-15 |
Chroma Therapeutics Ltd |
Enzyme inhibitors
|
|
AR057061A1
(es)
|
2005-06-16 |
2007-11-14 |
Altana Pharma Ag |
Espiro-bencimidazoles farmaceuticamente activos y su uso en la fabricacion de medicamentos
|
|
BRPI0611948A2
(pt)
|
2005-06-17 |
2010-10-13 |
Wyeth Corp |
compostos úteis como inibidores de serotonina e agonistas de antagonista de 5-ht1a
|
|
JP2008546736A
(ja)
|
2005-06-22 |
2008-12-25 |
ニコメッド ゲゼルシャフト ミット ベシュレンクテル ハフツング |
三環式ベンゾイミダゾールの製造のための中間体の製造方法
|
|
US7456195B2
(en)
|
2005-06-24 |
2008-11-25 |
Bristol-Myers Squibb Company |
Phenylglycinamide and pyridylglycinamide derivatives useful as anticoagulants
|
|
JP2009504798A
(ja)
|
2005-08-22 |
2009-02-05 |
ニコメッド ゲゼルシャフト ミット ベシュレンクテル ハフツング |
同位体置換されたベンゾイミダゾール誘導体
|
|
JP2009509923A
(ja)
*
|
2005-08-26 |
2009-03-12 |
メシルジーン、インコーポレイテッド |
ヒストンデアセチラーゼのベンゾジアゼピン及びベンゾピペラジン類似体阻害薬
|
|
GB0518237D0
(en)
|
2005-09-07 |
2005-10-19 |
Angeletti P Ist Richerche Bio |
Therapeutic compounds
|
|
US8119655B2
(en)
|
2005-10-07 |
2012-02-21 |
Takeda Pharmaceutical Company Limited |
Kinase inhibitors
|
|
GB0522881D0
(en)
|
2005-11-10 |
2005-12-21 |
Angeletti P Ist Richerche Bio |
Therapeutic compounds
|
|
JP5249772B2
(ja)
|
2005-11-22 |
2013-07-31 |
メルク・シャープ・アンド・ドーム・コーポレーション |
キナーゼの阻害剤として有用な三環式化合物
|
|
AR057579A1
(es)
|
2005-11-23 |
2007-12-05 |
Merck & Co Inc |
Compuestos espirociclicos como inhibidores de histona de acetilasa (hdac)
|
|
US20090221589A1
(en)
|
2005-12-19 |
2009-09-03 |
Thomas Trieselmann |
Use of aminoalcohol derivatives for the treatment of overactive bladder
|
|
DE102005061655A1
(de)
|
2005-12-22 |
2007-06-28 |
Merck Patent Gmbh |
Diazepinone
|
|
PE20071241A1
(es)
|
2006-01-17 |
2008-01-14 |
Schering Corp |
Compuestos derivados de hidantoina para el tratamiento de trastornos inflamatorios
|
|
US8222423B2
(en)
|
2006-02-14 |
2012-07-17 |
Dana-Farber Cancer Institute, Inc. |
Bifunctional histone deacetylase inhibitors
|
|
WO2007100536A1
(en)
|
2006-02-24 |
2007-09-07 |
Wyeth |
DIHYDROSPIRO[DIBENZO[A,D][7]ANNULENE-5,4'-IMIDAZOL] COMPOUNDS FOR THE INHIBITION OF β-SECRETASE
|
|
US8338416B2
(en)
|
2006-03-16 |
2012-12-25 |
Pharmacylics, Inc. |
Indole derivatives as inhibitors of histone deacetylase
|
|
CA2652307A1
(en)
|
2006-04-10 |
2007-10-18 |
Painceptor Pharma Corporation |
Compositions and methods for modulating gated ion channels
|
|
AU2007297573A1
(en)
|
2006-06-12 |
2008-03-27 |
Viamet Pharmaceuticals, Inc. |
Metallo-hydrolase inhibitors using metal binding moieties in combination with targeting moieties
|
|
TW200808707A
(en)
|
2006-06-14 |
2008-02-16 |
Methylgene Inc |
Sulfamide and sulfamate derivatives as histone deacetylase inhibitors
|
|
CN101108859A
(zh)
|
2006-07-17 |
2008-01-23 |
上海恒瑞医药有限公司 |
长春碱类化合物、其制备方法及其在医药上的用途
|
|
WO2008014307A2
(en)
|
2006-07-26 |
2008-01-31 |
Novartis Ag |
Inhibitors of undecaprenyl pyrophosphate synthase
|
|
US20100173332A1
(en)
|
2006-09-07 |
2010-07-08 |
Auckland Uniservices Limited |
Method for the Fluorescent Detection of Nitroreductase Activity Using Nitro-Substituted Aromatic Compounds
|
|
WO2008048648A2
(en)
|
2006-10-17 |
2008-04-24 |
Acadia Pharmaceuticals Inc. |
Cb1-modulating compounds and their use
|
|
WO2008046155A1
(en)
|
2006-10-20 |
2008-04-24 |
Dia-B Tech Limited |
Methods for regulating glucose homeostasis and agents therefor
|
|
CN105481788A
(zh)
|
2006-10-28 |
2016-04-13 |
梅特希尔基因公司 |
组蛋白脱乙酰酶抑制剂
|
|
WO2008053131A1
(en)
|
2006-10-30 |
2008-05-08 |
Chroma Therapeutics Ltd. |
Hydroxamates as inhibitors of histone deacetylase
|
|
WO2008061160A1
(en)
|
2006-11-14 |
2008-05-22 |
Pharmacyclics, Inc. |
Uses of selective inhibitors of hdac8 for treatment of inflammatory conditions
|
|
US7820711B2
(en)
|
2006-11-14 |
2010-10-26 |
Pharmacyclics Inc. |
Uses of selective inhibitors of HDAC8 for treatment of T-cell proliferative disorders
|
|
US7951795B2
(en)
|
2006-12-08 |
2011-05-31 |
Merck Sharp & Dohme Corp. |
Constrained spirocyclic compounds as CGRP receptor antagonists
|
|
WO2008071765A1
(en)
|
2006-12-14 |
2008-06-19 |
Nycomed Gmbh |
Pharmaceutically active spiro-substituted benzimidazole derivatives
|
|
WO2008074858A1
(en)
|
2006-12-21 |
2008-06-26 |
Nycomed Gmbh |
Intermediates and process for the production of 5-substituted tricyclic benzimidazoles
|
|
CA2677649A1
(en)
|
2007-02-09 |
2008-08-21 |
Forest Laboratories Holdings Limited |
Bioavailable formulations of heterocyclic compounds
|
|
WO2008101186A1
(en)
|
2007-02-15 |
2008-08-21 |
The J. David Gladstone Institutes |
Inhibitors for hdac8
|
|
DE102007013854A1
(de)
|
2007-03-20 |
2008-09-25 |
Merck Patent Gmbh |
Tetrahydrochinoline
|
|
DE102007013855A1
(de)
|
2007-03-20 |
2008-09-25 |
Merck Patent Gmbh |
Substituierte Tetrahydrochinoline
|
|
DE102007013856A1
(de)
|
2007-03-20 |
2008-09-25 |
Merck Patent Gmbh |
Substituierte Tetrahydropyrrolochinoline
|
|
US20090105283A1
(en)
|
2007-04-11 |
2009-04-23 |
Dmitry Koltun |
3-HYDROQUINAZOLIN-4-ONE DERIVATIVES FOR USE AS STEAROYL CoA DESATURASE INHIBITORS
|
|
US20080255161A1
(en)
|
2007-04-11 |
2008-10-16 |
Dmitry Koltun |
3-HYDROQUINAZOLIN-4-ONE DERIVATIVES FOR USE AS STEAROYL CoA DESATURASE INHIBITORS
|
|
CN101784516B
(zh)
|
2007-06-13 |
2014-07-02 |
百时美施贵宝公司 |
作为凝血因子抑制剂的二肽类似物
|
|
WO2009015208A1
(en)
|
2007-07-23 |
2009-01-29 |
Replidyne, Inc. |
Antibacterial amide and sulfonamide substituted heterocyclic urea compounds
|
|
TW200940542A
(en)
|
2008-01-09 |
2009-10-01 |
Array Biopharma Inc |
Pyrimidyl cyclopentanes as AKT protein kinase inhibitors
|
|
US8987468B2
(en)
|
2008-02-04 |
2015-03-24 |
The Translational Genomics Research Institute |
Compounds, pharmaceutical compositions and methods of use of hydroxamic acid derivatives
|
|
WO2009100406A2
(en)
|
2008-02-07 |
2009-08-13 |
Synta Pharmaceuticals Corp. |
Topical formulations for the treatment of psoriasis
|
|
JP2009191041A
(ja)
|
2008-02-18 |
2009-08-27 |
Univ Of Tokyo |
ヒドロキシメチルケトン誘導体
|
|
EP2100879A1
(en)
|
2008-03-13 |
2009-09-16 |
4Sc Ag |
Novel N-substituted tetrahydroisoquinoline/isoindoline hydroxamic acid compounds
|
|
US8436005B2
(en)
|
2008-04-03 |
2013-05-07 |
Abbott Laboratories |
Macrocyclic pyrimidine derivatives
|
|
EP2311840A1
(en)
|
2009-10-13 |
2011-04-20 |
DAC S.r.l. |
Spirocyclic derivatives as histone deacetylase inhibitors
|
|
US8980877B2
(en)
|
2008-04-15 |
2015-03-17 |
Dac S.R.L. |
Spirocyclic derivatives as histone deacetylase inhibitors
|
|
EP2110377A1
(en)
|
2008-04-15 |
2009-10-21 |
DAC S.r.l. |
Spirocyclic derivatives as histone deacetylase inhibitors
|
|
US8546410B2
(en)
|
2008-05-05 |
2013-10-01 |
Abbvie Inc. |
Heteroaryl-fused macrocyclic pyrimidine derivatives
|
|
WO2009137503A1
(en)
|
2008-05-05 |
2009-11-12 |
Envivo Pharmaceuticals, Inc. |
Hdac inhibitors and uses thereof
|
|
EP2303888B1
(en)
|
2008-06-12 |
2015-05-06 |
President and Fellows of Harvard College |
Compounds for antimicrobial intervention
|
|
WO2009152210A2
(en)
|
2008-06-12 |
2009-12-17 |
National Health Research Institutes |
Coumarin compounds and their use for treating cancer
|
|
AU2009289649B2
(en)
|
2008-09-03 |
2016-05-05 |
Biomarin Pharmaceutical Inc. |
Compositions including 6-aminohexanoic acid derivatives as HDAC inhibitors
|
|
MY148558A
(en)
|
2008-09-11 |
2013-04-30 |
Amgen Inc |
Spiro-tetracyclic ring compounds as betasecretase modulators and methods of use
|
|
AR073630A1
(es)
|
2008-10-07 |
2010-11-17 |
Schering Corp |
Analogos de espiroaminooxazolina como moduladores de los receptores adrenergicos alfa2c
|
|
US9040528B2
(en)
|
2008-10-14 |
2015-05-26 |
Astrazeneca Ab |
Chemical compounds 542
|
|
UY32174A
(es)
|
2008-10-14 |
2010-05-31 |
Astrazeneca Ab |
Nuevos heterociclos sustituidos, composiciones farmaceuticas conteniendolos, procedimientos de preparacion y aplicaciones
|
|
WO2010056230A1
(en)
|
2008-10-15 |
2010-05-20 |
Cv Therapeutics, Inc. |
3-hydroquinazolin-4-one derivatives for use as stearoyl coa desaturase inhibitors
|
|
US8569336B2
(en)
|
2008-11-10 |
2013-10-29 |
Ling Tong |
Compounds for the treatment of inflammatory disorders
|
|
GB2465405A
(en)
|
2008-11-10 |
2010-05-19 |
Univ Basel |
Triazine, pyrimidine and pyridine analogues and their use in therapy
|
|
AU2009314760B2
(en)
|
2008-11-11 |
2011-11-10 |
Je Il Pharmaceutical Co.,Ltd |
Novel tricyclic derivative or pharmaceutically acceptable salts thereof, preparation method thereof, and pharmaceutical composition containing the same
|
|
US20110319416A1
(en)
|
2009-01-28 |
2011-12-29 |
Emory University |
Subunit Selective NMDA Receptor Antagonists For The Treatment Of Neurological Conditions
|
|
TW201038569A
(en)
|
2009-02-16 |
2010-11-01 |
Abbott Gmbh & Co Kg |
Heterocyclic compounds, pharmaceutical compositions containing them, and their use in therapy
|
|
DK2410844T3
(en)
|
2009-03-27 |
2016-07-04 |
Merck Sharp & Dohme |
Inhibitors of hepatitis C virus replication
|
|
BRPI1014821A2
(pt)
|
2009-04-09 |
2016-04-05 |
Boehringer Ingelheim Int |
"inibidores de replicação de hiv"
|
|
WO2010125469A1
(en)
|
2009-04-29 |
2010-11-04 |
Glenmark Pharmaceuticals, S.A. |
Pyrimidinedione-fused heterocyclic compounds as trpa1 modulators
|
|
US8624040B2
(en)
|
2009-06-22 |
2014-01-07 |
Millennium Pharmaceuticals, Inc. |
Substituted hydroxamic acids and uses thereof
|
|
CA2765678A1
(en)
|
2009-06-22 |
2010-12-29 |
Christopher Blackburn |
Substituted hydroxamic acids and uses thereof
|
|
AU2010263113B2
(en)
|
2009-06-23 |
2015-11-26 |
Translational Drug Development, Llc |
Benzamide derivatives
|
|
EP2266985A1
(en)
|
2009-06-26 |
2010-12-29 |
Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts |
Tricyclic Pyrimidine Derivatives as Wnt antagonists
|
|
US8513433B2
(en)
|
2009-07-02 |
2013-08-20 |
Angion Biomedica Corp. |
Small molecule inhibitors of PARP activity
|
|
ES2736200T3
(es)
|
2009-07-22 |
2019-12-26 |
Univ Illinois |
Inhibidores de HDAC y métodos terapéuticos que utilizan los mismos
|
|
US20110071136A1
(en)
|
2009-09-16 |
2011-03-24 |
Cylene Pharmaceuticals, Inc |
Novel tricyclic protein kinase modulators
|
|
US8263633B2
(en)
|
2009-09-28 |
2012-09-11 |
F. Hoffman-La Roche Ag |
Benzoxepin PI3K inhibitor compounds and methods of use
|
|
MY160064A
(en)
|
2009-09-28 |
2017-02-15 |
Hoffmann La Roche |
Benzoxazepin pi3k inhibitor compounds and methods of use
|
|
EP2305643A1
(en)
|
2009-10-02 |
2011-04-06 |
Ikerchem, S.L. |
New histone deacetylase inhibitors based simultaneously on trisubstituted 1h-pyrroles and aromatic and heteroaromatic spacers
|
|
US9221773B2
(en)
|
2009-12-22 |
2015-12-29 |
The Translational Genomics Research Institute |
Benzamide derivatives
|
|
US8198290B2
(en)
|
2009-12-23 |
2012-06-12 |
Berry And Associates, Inc. |
Methoxatin derivatives
|
|
US20130040998A1
(en)
|
2010-01-08 |
2013-02-14 |
Dana-Farber Cancer Institute, Inc. |
Fluorinated hdac inhibitors and uses thereof
|
|
AU2011205283B2
(en)
|
2010-01-13 |
2014-07-10 |
Tempero Pharmaceuticals, Inc. |
Compounds and methods
|
|
JP2011148714A
(ja)
|
2010-01-19 |
2011-08-04 |
Nippon Soda Co Ltd |
病害防除方法
|
|
PH12012501492B1
(en)
|
2010-01-22 |
2020-01-24 |
Acetylon Pharmaceuticals Inc |
Reverse amide compounds as protein deacetylase inhibitors and methods of use thereof
|
|
US8519122B2
(en)
|
2010-02-12 |
2013-08-27 |
The Regents Of The University Of California |
Compositions and methods for modification of biomolecules
|
|
WO2011106632A1
(en)
|
2010-02-26 |
2011-09-01 |
Millennium Pharmaceuticals, Inc. |
Substituted hydroxamic acids and uses thereof
|
|
WO2011106627A1
(en)
|
2010-02-26 |
2011-09-01 |
Millennium Pharmaceuticals, Inc. |
Substituted hydroxamic acids and uses thereof
|
|
US8946223B2
(en)
|
2010-04-12 |
2015-02-03 |
Millennium Pharmaceuticals, Inc. |
Substituted hydroxamic acids and uses thereof
|
|
JO3131B1
(ar)
|
2010-04-27 |
2017-09-20 |
Glaxosmithkline Llc |
مركبات كيميائية
|
|
US8513421B2
(en)
|
2010-05-19 |
2013-08-20 |
Millennium Pharmaceuticals, Inc. |
Substituted hydroxamic acids and uses thereof
|
|
WO2011159857A1
(en)
|
2010-06-16 |
2011-12-22 |
Bristol-Myers Squibb Company |
Carboline carboxamide compounds useful as kinase inhibitors
|
|
US20120015942A1
(en)
|
2010-07-19 |
2012-01-19 |
Millennium Pharmaceuticals, Inc. |
Substituted hydroxamic acids and uses thereof
|
|
WO2012012322A1
(en)
|
2010-07-19 |
2012-01-26 |
Millennium Pharmaceuticals, Inc. |
Substituted hydroxamic acids and uses thereof
|
|
EP2598133A4
(en)
|
2010-07-30 |
2014-03-05 |
Univ California |
METHOD AND THERAPEUTIC FOR TREATING AND CONTROLLING MEMBERSHIP EDUCATION
|
|
US8471026B2
(en)
|
2010-08-26 |
2013-06-25 |
Millennium Pharmaceuticals, Inc. |
Substituted hydroxamic acids and uses thereof
|
|
BR112013005609A2
(pt)
|
2010-09-09 |
2019-09-24 |
Hoffmann La Roche |
composto de fórmula (i), composição, uso de um composto e novos compostos, processos, método e usos
|
|
ES2647368T3
(es)
|
2010-10-08 |
2017-12-21 |
Vib Vzw |
Inhibidores de HDAC para tratar la enfermedad de Charcot-Marie-Tooth
|
|
WO2012045194A1
(en)
|
2010-10-09 |
2012-04-12 |
Abbott Laboratories |
Benzodiazepinones as fak inhibitors for treatment of cancer
|
|
US8765773B2
(en)
|
2010-10-18 |
2014-07-01 |
Millennium Pharmaceuticals, Inc. |
Substituted hydroxamic acids and uses thereof
|
|
US20140031302A1
(en)
|
2010-10-22 |
2014-01-30 |
Universite De Strasbourg |
Pochoxime conjugates useful for the treatment of hsp90 related pathologies
|
|
NZ610225A
(en)
|
2010-11-16 |
2015-08-28 |
Acetylon Pharmaceuticals Inc |
Pyrimidine hydroxy amide compounds as protein deacetylase inhibitors and methods of use thereof
|
|
CN102558200A
(zh)
|
2010-12-21 |
2012-07-11 |
复旦大学 |
长春碱类衍生物、其制备方法及其在医药上的用途
|
|
WO2012088015A2
(en)
|
2010-12-22 |
2012-06-28 |
Millennium Pharmaceuticals, Inc. |
Substituted hydroxamic acids and uses thereof
|
|
WO2012085003A1
(en)
|
2010-12-22 |
2012-06-28 |
Katholieke Universiteit Leuven, K.U. Leuven R&D |
2-hydroxyisoquinoline-1,3(2h,4h)-diones and related compounds useful as hiv replication inhibitors
|
|
WO2012096832A2
(en)
|
2011-01-12 |
2012-07-19 |
Crystal Biopharmaceutical Llc |
Hdac inhibiting derivatives of camptothecin
|
|
WO2012102985A1
(en)
|
2011-01-24 |
2012-08-02 |
Glaxosmithkline Llc |
Isoquinoline compounds and methods for treating hiv
|
|
AU2012212323A1
(en)
|
2011-02-01 |
2013-09-12 |
The Board Of Trustees Of The University Of Illinois |
HDAC inhibitors and therapeutic methods using the same
|
|
WO2012106472A1
(en)
|
2011-02-02 |
2012-08-09 |
Fibrogen, Inc. |
Naphthyridine derivatives as inhibitors of hypoxia inducible factor (hif) hydroxylase
|
|
US9346827B2
(en)
|
2011-02-07 |
2016-05-24 |
Amgen Inc. |
5-amino-oxazepine and 5-amino-thiazepane compounds as beta secretase antagonists and methods of use
|
|
US20120245193A1
(en)
|
2011-02-14 |
2012-09-27 |
Alkermes, Inc. |
PERIPHERIALLY ACTING μ OPIOID ANTAGONISTS
|
|
EP2675810A1
(en)
|
2011-02-15 |
2013-12-25 |
Amgen Inc. |
Spiro-amino-imidazo-fused heterocyclic compounds as beta-secretase modulators and methods of use
|
|
WO2012110860A1
(en)
|
2011-02-17 |
2012-08-23 |
Glenmark Pharmaceuticals S.A. |
TRICYCLIC COMPOUNDS AS mPGES-1 INHIBITORS
|
|
WO2012117421A1
(en)
|
2011-03-02 |
2012-09-07 |
Orchid Research Laboratories Ltd |
Histone deacetylase inhibitors
|
|
US9090628B2
(en)
|
2011-03-21 |
2015-07-28 |
Genentech, Inc. |
Benzoxazepin compounds selective for PI3K P110 delta and methods of use
|
|
CN102838625B
(zh)
|
2011-06-22 |
2015-04-15 |
中国科学院上海药物研究所 |
四氢吡啶并噻唑类化合物、其制备方法、包含该化合物的药物组合物及其用途
|
|
US20150197497A1
(en)
|
2011-06-24 |
2015-07-16 |
Dana-Farber Cancer Institute, Inc. |
Selective inhibitors of histone deacetylase isoform 6 and methods thereof
|
|
WO2013006408A1
(en)
|
2011-07-01 |
2013-01-10 |
Tempero Pharmaceuticals, Inc. |
Compounds and methods
|
|
EA201490228A1
(ru)
|
2011-07-08 |
2014-08-29 |
Новартис Аг |
Новые производные трифторметилоксадиазола и их применение для лечения заболевания
|
|
WO2013009827A1
(en)
|
2011-07-13 |
2013-01-17 |
Tempero Pharmaceuticals, Inc. |
Methods of treatment
|
|
EP2734500A4
(en)
|
2011-07-20 |
2015-04-08 |
Gen Hospital Corp |
SELECTIVE HISTONDEACETYLASE-6 INHIBITORS FOR THE TREATMENT OF BONE DISORDERS
|
|
SI2750677T1
(sl)
|
2011-08-30 |
2017-10-30 |
Chdi Foundation, Inc. |
Inhibitorji kinurenin-3-monooksigenaze, farmacevtski sestavki in postopki njihove uporabe
|
|
WO2013044092A1
(en)
|
2011-09-21 |
2013-03-28 |
Amgen Inc. |
Amino-oxazines and amino-dihydrothiazine compounds as beta-secretase modulators and methods of use
|
|
US20140241990A1
(en)
|
2011-09-30 |
2014-08-28 |
Tufts University |
Methods of using adenosine a1 receptor activation for treating depression
|
|
CA2850757A1
(en)
|
2011-10-03 |
2013-04-11 |
The Trustees Of Columbia University In The City Of New York |
Novel molecules that selectively inhibit histone deacetylase 6 relative to histone deacetylase 1
|
|
JP6224600B2
(ja)
|
2011-10-18 |
2017-11-01 |
エコール ポリテクニーク フェデラル ドゥ ローザンヌ(エーペーエフエル) |
電気化学および/または光電子デバイス用化合物
|
|
WO2013059582A2
(en)
|
2011-10-20 |
2013-04-25 |
Nupotential, Inc. |
Small molecule inhibitors of histone deacteylases
|
|
IN2014MN01378A
(enExample)
|
2011-12-11 |
2015-07-03 |
Viamet Pharmaceuticals Inc |
|
|
MX375348B
(es)
|
2011-12-15 |
2025-03-06 |
Alkermes Pharma Ireland Ltd |
Composiciones de la buprenorfina y antagonistas de los receptores opioide-mu.
|
|
JP6233812B2
(ja)
|
2012-03-07 |
2017-11-22 |
エイチ リー モフィット キャンサー センター アンド リサーチ インスティテュート インコーポレイテッド |
選択的ヒストンデアセチラーゼ6阻害剤
|
|
GB2503789A
(en)
|
2012-05-15 |
2014-01-08 |
Syngenta Participations Ag |
Quinazoline derivatives as antifungal agents
|
|
US10544090B2
(en)
|
2012-07-10 |
2020-01-28 |
Georgia State University Research Foundation, Inc. |
Anthraquinone analogs and methods of making and using thereof
|
|
WO2014011911A2
(en)
|
2012-07-11 |
2014-01-16 |
Nimbus Iris, Inc. |
Irak inhibitors and uses thereof
|
|
WO2014011902A1
(en)
|
2012-07-11 |
2014-01-16 |
Nimbus Iris, Inc. |
Irak inhibitors and uses thereof
|
|
WO2014018919A1
(en)
|
2012-07-27 |
2014-01-30 |
The Regents Of The University Of California |
Seriniquinones, melanoma-specific anticancer agents
|
|
US20150216171A1
(en)
|
2012-09-05 |
2015-08-06 |
Bayer Cropscience Ag |
Herbicidally active bicycloaryl carboxylic acid amides
|
|
EP2900672B1
(de)
|
2012-09-28 |
2017-02-22 |
Bayer Pharma Aktiengesellschaft |
Bet-proteininhibitorische 5-aryl-triazolo-azepine
|
|
EP2943204B1
(en)
|
2013-01-10 |
2019-03-13 |
Venatorx Pharmaceuticals Inc |
Beta-lactamase inhibitors
|
|
JP6321685B2
(ja)
|
2013-02-25 |
2018-05-09 |
メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツングMerck Patent Gesellschaft mit beschraenkter Haftung |
2−アミノ−3,4−ジヒドロ−キナゾリン誘導体、およびそのカテプシンd阻害剤としての使用
|
|
WO2014134127A1
(en)
|
2013-02-26 |
2014-09-04 |
Northeastern University |
Cannabinergic nitrate esters and related analogs
|
|
BR112015027114B1
(pt)
|
2013-04-29 |
2021-12-21 |
Chong Kun Dang Pharmaceutical Corp |
Compostos inibidores seletivos de histona desacetilase e seu uso
|
|
WO2014177469A1
(en)
|
2013-04-30 |
2014-11-06 |
Boehringer Ingelheim International Gmbh,M |
Diaminopyrazine compounds, medicaments containing said compounds, use thereof and processes for the preparation thereof
|
|
US9278963B2
(en)
|
2013-10-10 |
2016-03-08 |
Acetylon Pharmaceuticals, Inc. |
Pyrimidine hydroxy amide compounds as histone deacetylase inhibitors
|
|
JP6392888B2
(ja)
|
2014-03-12 |
2018-09-19 |
チョン クン ダン ファーマシューティカル コーポレーション |
ヒストン脱アセチル化酵素6阻害剤としての新規化合物およびこれを含む薬剤学的組成物
|
|
TW201636329A
(zh)
|
2015-02-02 |
2016-10-16 |
佛瑪治療公司 |
作為hdac抑制劑之雙環[4,6,0]異羥肟酸
|
|
PL3292116T3
(pl)
|
2015-02-02 |
2022-02-21 |
Valo Health, Inc. |
3-arylo-4-amidobicykliczne kwasy [4,5,0]hydroksamowe jako inhibitory hdac
|
|
GB201505133D0
(en)
*
|
2015-03-26 |
2015-05-06 |
Egerton Charles E And Scott Harden Simon |
Self-propelled water board apparatus
|
|
WO2016168598A1
(en)
|
2015-04-17 |
2016-10-20 |
Forma Therapeutics, Inc. |
3-spirocyclic-6-hydroxamic acid tetralins as hdac inhibitors
|
|
JP6697074B2
(ja)
|
2015-10-12 |
2020-05-20 |
チョン クン ダン ファーマシューティカル コーポレーション |
ヒストン脱アセチル化酵素6阻害剤としてのオキサジアゾールアミン誘導体化合物及びこれを含有する薬剤学的組成物
|
|
EP3472131B1
(en)
|
2016-06-17 |
2020-02-19 |
Forma Therapeutics, Inc. |
2-spiro-5- and 6-hydroxamic acid indanes as hdac inhibitors
|