JP2018076328A5 - - Google Patents
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- JP2018076328A5 JP2018076328A5 JP2017229034A JP2017229034A JP2018076328A5 JP 2018076328 A5 JP2018076328 A5 JP 2018076328A5 JP 2017229034 A JP2017229034 A JP 2017229034A JP 2017229034 A JP2017229034 A JP 2017229034A JP 2018076328 A5 JP2018076328 A5 JP 2018076328A5
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- JP
- Japan
- Prior art keywords
- pharmaceutical composition
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- dose
- contrast agent
- subject
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 239000008194 pharmaceutical composition Substances 0.000 claims 27
- 239000002872 contrast media Substances 0.000 claims 17
- 230000000144 pharmacologic effect Effects 0.000 claims 5
- 238000003384 imaging method Methods 0.000 claims 4
- 238000000034 method Methods 0.000 claims 3
- 208000024172 Cardiovascular disease Diseases 0.000 claims 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims 2
- OIRDTQYFTABQOQ-KQYNXXCUSA-N adenosine group Chemical group [C@@H]1([C@H](O)[C@H](O)[C@@H](CO)O1)N1C=NC=2C(N)=NC=NC12 OIRDTQYFTABQOQ-KQYNXXCUSA-N 0.000 claims 2
- 239000003795 chemical substances by application Substances 0.000 claims 2
- 229940124549 vasodilator Drugs 0.000 claims 2
- 239000003071 vasodilator agent Substances 0.000 claims 2
- 239000002126 C01EB10 - Adenosine Substances 0.000 claims 1
- 229960005305 adenosine Drugs 0.000 claims 1
- 210000000748 cardiovascular system Anatomy 0.000 claims 1
- 150000001875 compounds Chemical class 0.000 claims 1
- 208000029078 coronary artery disease Diseases 0.000 claims 1
- 238000002347 injection Methods 0.000 claims 1
- 239000007924 injection Substances 0.000 claims 1
- 238000001990 intravenous administration Methods 0.000 claims 1
- 208000031225 myocardial ischemia Diseases 0.000 claims 1
- 238000002600 positron emission tomography Methods 0.000 claims 1
- 229960003614 regadenoson Drugs 0.000 claims 1
- LZPZPHGJDAGEJZ-AKAIJSEGSA-N regadenoson Chemical compound C1=C(C(=O)NC)C=NN1C1=NC(N)=C(N=CN2[C@H]3[C@@H]([C@H](O)[C@@H](CO)O3)O)C2=N1 LZPZPHGJDAGEJZ-AKAIJSEGSA-N 0.000 claims 1
- PPASLZSBLFJQEF-RXSVEWSESA-M sodium-L-ascorbate Chemical compound [Na+].OC[C@H](O)[C@H]1OC(=O)C(O)=C1[O-] PPASLZSBLFJQEF-RXSVEWSESA-M 0.000 claims 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 1
- 0 CC(C)(C)N(C1=O)N=CC([U]Cc2ccc(COCC*)cc2)=C1Cl Chemical compound CC(C)(C)N(C1=O)N=CC([U]Cc2ccc(COCC*)cc2)=C1Cl 0.000 description 1
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US30247710P | 2010-02-08 | 2010-02-08 | |
| US61/302,477 | 2010-02-08 | ||
| US31537610P | 2010-03-18 | 2010-03-18 | |
| US61/315,376 | 2010-03-18 | ||
| US33369310P | 2010-05-11 | 2010-05-11 | |
| US61/333,693 | 2010-05-11 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015181159A Division JP6254126B2 (ja) | 2010-02-08 | 2015-09-14 | 造影剤およびその中間体を合成するための方法および装置 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018076328A JP2018076328A (ja) | 2018-05-17 |
| JP2018076328A5 true JP2018076328A5 (enExample) | 2018-06-28 |
| JP6685269B2 JP6685269B2 (ja) | 2020-04-22 |
Family
ID=44356121
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012552155A Active JP6092628B2 (ja) | 2010-02-08 | 2011-02-08 | 造影剤およびその中間体を合成するための方法および装置 |
| JP2015181159A Active JP6254126B2 (ja) | 2010-02-08 | 2015-09-14 | 造影剤およびその中間体を合成するための方法および装置 |
| JP2017229034A Active JP6685269B2 (ja) | 2010-02-08 | 2017-11-29 | 造影剤およびその中間体を合成するための方法および装置 |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012552155A Active JP6092628B2 (ja) | 2010-02-08 | 2011-02-08 | 造影剤およびその中間体を合成するための方法および装置 |
| JP2015181159A Active JP6254126B2 (ja) | 2010-02-08 | 2015-09-14 | 造影剤およびその中間体を合成するための方法および装置 |
Country Status (19)
| Country | Link |
|---|---|
| US (6) | US8936777B2 (enExample) |
| EP (3) | EP4046990A1 (enExample) |
| JP (3) | JP6092628B2 (enExample) |
| KR (5) | KR102438133B1 (enExample) |
| CN (3) | CN102858752B (enExample) |
| AU (3) | AU2011213568B2 (enExample) |
| BR (1) | BR112012019789A2 (enExample) |
| CA (1) | CA2789044C (enExample) |
| DK (2) | DK3323810T3 (enExample) |
| ES (2) | ES2909318T3 (enExample) |
| IL (2) | IL221253B (enExample) |
| MX (2) | MX348958B (enExample) |
| NO (1) | NO2534136T3 (enExample) |
| NZ (1) | NZ602291A (enExample) |
| PT (2) | PT2534136T (enExample) |
| RU (1) | RU2631500C2 (enExample) |
| SG (2) | SG10201500929XA (enExample) |
| TW (4) | TWI589302B (enExample) |
| WO (1) | WO2011097649A2 (enExample) |
Families Citing this family (44)
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| CN101687780B (zh) | 2006-12-26 | 2016-01-20 | 兰休斯医疗成像公司 | 用于使心脏神经支配成像的配体 |
| JP5946992B2 (ja) | 2008-02-29 | 2016-07-06 | ランセウス メディカル イメージング， インコーポレイテッド | 灌流造影を含む適用のための造影剤 |
| CN107261159B (zh) | 2009-04-15 | 2021-01-12 | 兰休斯医疗成像公司 | 使用抗坏血酸稳定化放射性药物组合物 |
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| AU2012250539A1 (en) * | 2011-05-05 | 2013-12-19 | Cedars-Sinai Medical Center | Assessment of coronary heart disease with carbon dioxide |
| EP2753605B1 (en) * | 2011-09-09 | 2019-03-27 | Lantheus Medical Imaging, Inc. | Compositions, methods, and systems for the synthesis and use of imaging agents |
| CA2852395C (en) * | 2011-10-21 | 2020-04-28 | Lantheus Medical Imaging, Inc. | Compositions comprising ascorbic acid and pyridaben and pyridaben analogs attached to an imaging moiety and related methods |
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| JP6060302B1 (ja) * | 2016-06-10 | 2017-01-11 | 日本メジフィジックス株式会社 | 心筋核医学画像データの解析方法及び解析装置 |
| TWI649067B (zh) * | 2017-03-01 | 2019-02-01 | 醫百科技股份有限公司 | Positioning corrector |
| CN108129673B (zh) * | 2017-12-26 | 2020-10-13 | 武汉大学 | 一种高灵敏度水溶性树枝状大分子f19显影剂的制备及其应用 |
| GB201805253D0 (en) | 2018-03-29 | 2018-05-16 | Ge Healthcare Ltd Ip | Solid phase extraction |
| CN108658868A (zh) * | 2018-05-07 | 2018-10-16 | 四川大学 | 一种碳酸氢盐离子液体及其制备方法以及一种三氨基三硝基苯的重结晶方法 |
| EP3671511B1 (en) | 2018-12-19 | 2022-07-06 | Rohde & Schwarz GmbH & Co. KG | Communication system and method |
| CN109806822B (zh) * | 2019-01-30 | 2021-07-30 | 杭州吉蕊科技有限公司 | 一种模块化、多功能的pet探针自动化合成系统 |
| CN109896934A (zh) * | 2019-03-08 | 2019-06-18 | 山东省药学科学院 | 一种高纯度2-苄氧基溴乙烷的制备方法 |
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| GB201919016D0 (en) * | 2019-12-20 | 2020-02-05 | Ge Healthcare Ltd | Apparatus and method for solid phase extraction |
| CN111333638A (zh) * | 2020-03-17 | 2020-06-26 | 四川大学华西医院 | 18f标记的异喹啉并哒嗪酮类化合物及其合成方法和应用 |
| JP7362561B2 (ja) * | 2020-07-30 | 2023-10-17 | 富士フイルム株式会社 | 放射線画像処理装置、方法およびプログラム |
| EP4351410A4 (en) * | 2021-06-11 | 2025-07-02 | Jubilant Draximage Inc | Non-invasive imaging techniques for diagnosing peripheral arterial disease |
| GB202108605D0 (en) | 2021-06-16 | 2021-07-28 | Ge Healthcare Uk Ltd | Effect of water content |
| GB202108608D0 (en) | 2021-06-16 | 2021-07-28 | Ge Healthcare Ltd | Preparation of a ph-adjusted ascorbic acid solution |
| CN114700006B (zh) * | 2022-06-07 | 2023-03-24 | 北京先通国际医药科技股份有限公司 | 一种液体组合物的生产设备及其制备方法和用途 |
| CN114716415B (zh) * | 2022-06-09 | 2022-09-02 | 北京先通国际医药科技股份有限公司 | 生产液体组合物的设备及其制备方法和用途 |
| CN114732918B (zh) * | 2022-06-10 | 2022-09-13 | 北京先通国际医药科技股份有限公司 | 一种液体组合物的生产设备及其制备方法和用途 |
| CN114773179B (zh) * | 2022-06-23 | 2022-09-16 | 北京先通国际医药科技股份有限公司 | 一种化合物ⅰ液体组合物的制备方法、及其在心肌代谢pet显像上的用途 |
| US20250019350A1 (en) | 2023-06-16 | 2025-01-16 | Progenics Pharmaceuticals, Inc | Synthesis of the prostate specific membrane antigen (psma) radiolabeled inhibitor [18f]dcfpyl |
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