JP2017533886A5 - - Google Patents

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JP2017533886A5
JP2017533886A5 JP2017514635A JP2017514635A JP2017533886A5 JP 2017533886 A5 JP2017533886 A5 JP 2017533886A5 JP 2017514635 A JP2017514635 A JP 2017514635A JP 2017514635 A JP2017514635 A JP 2017514635A JP 2017533886 A5 JP2017533886 A5 JP 2017533886A5
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alkyl
amino
aryl
cycloalkyl
thio
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JP2017533886A (ja
JP6875273B2 (ja
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Priority claimed from PCT/CA2015/050910 external-priority patent/WO2016041082A1/en
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JP2017514635A 2014-09-17 2015-09-17 細胞傷害性及び抗有糸分裂性化合物、ならびにその使用方法 Active JP6875273B2 (ja)

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JP2021072535A JP7204083B2 (ja) 2014-09-17 2021-04-22 細胞傷害性及び抗有糸分裂性化合物、ならびにその使用方法

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462051883P 2014-09-17 2014-09-17
US62/051,883 2014-09-17
PCT/CA2015/050910 WO2016041082A1 (en) 2014-09-17 2015-09-17 Cytotoxic and anti-mitotic compounds, and methods of using the same

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JP2021072535A Division JP7204083B2 (ja) 2014-09-17 2021-04-22 細胞傷害性及び抗有糸分裂性化合物、ならびにその使用方法

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JP2017533886A JP2017533886A (ja) 2017-11-16
JP2017533886A5 true JP2017533886A5 (enExample) 2018-11-01
JP6875273B2 JP6875273B2 (ja) 2021-05-19

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JP2017514635A Active JP6875273B2 (ja) 2014-09-17 2015-09-17 細胞傷害性及び抗有糸分裂性化合物、ならびにその使用方法
JP2021072535A Active JP7204083B2 (ja) 2014-09-17 2021-04-22 細胞傷害性及び抗有糸分裂性化合物、ならびにその使用方法

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Country Status (21)

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US (5) US9879086B2 (enExample)
EP (2) EP4029873A1 (enExample)
JP (2) JP6875273B2 (enExample)
KR (2) KR102609034B1 (enExample)
CN (2) CN107001415B (enExample)
AU (2) AU2015318556C1 (enExample)
BR (1) BR112017005126B1 (enExample)
CA (1) CA2960899C (enExample)
CY (1) CY1124933T1 (enExample)
DK (1) DK3194421T3 (enExample)
ES (1) ES2905569T3 (enExample)
HR (1) HRP20220123T1 (enExample)
HU (1) HUE057768T2 (enExample)
IL (3) IL287645B2 (enExample)
MX (1) MX386008B (enExample)
PL (1) PL3194421T3 (enExample)
PT (1) PT3194421T (enExample)
RS (1) RS62860B1 (enExample)
RU (1) RU2723651C2 (enExample)
SG (1) SG11201702143PA (enExample)
WO (1) WO2016041082A1 (enExample)

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US10517958B2 (en) 2016-10-04 2019-12-31 Zymeworks Inc. Compositions and methods for the treatment of platinum-drug resistant cancer
CN118955721A (zh) 2018-01-04 2024-11-15 伊科尼克治疗公司 抗组织因子抗体、抗体-药物缀合物及相关方法
EP4253421A3 (en) 2018-03-13 2024-01-03 Zymeworks BC Inc. Anti-her2 biparatopic antibody-drug conjugates and methods of use
US20220257789A1 (en) * 2019-07-03 2022-08-18 Iconic Therapeutics, Inc. Anti-tissue factor antibody-drug conjugates and related methods
CA3081503A1 (en) 2019-12-06 2021-06-06 Zymeworks Inc. Methods of using a bispecific antigen-binding construct targeting her2 in combination with cdk4/6 inhibitors for the treatment of breast cancer
CN112285361B (zh) * 2020-09-27 2023-12-05 中国人民解放军空军军医大学 排除抗-cd38单克隆抗体药物对抗人球蛋白检测干扰的试剂
CN119894536A (zh) 2022-09-22 2025-04-25 乐普生物科技股份有限公司 Gpc3抗体药物偶联物及其应用

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