JP2017525767A5

JP2017525767A5 -

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Publication number: JP2017525767A5
Authority: JP; Japan
Prior art keywords: formula; compound; dermatologically acceptable; group; acceptable salt
Prior art date: 2015-08-20
Legal status : Granted

Application number

JP2017529598A

Other languages

English (en)

Japanese (ja)

Other versions

JP2017525767A (ja

JP6766047B2 (ja

Filing date

2015-08-20

Publication date

2018-09-27

2015-08-20 Application filed filed Critical

2015-08-20 Priority claimed from PCT/US2015/046120 external-priority patent/WO2016029021A1/en

2017-09-07 Publication of JP2017525767A publication Critical patent/JP2017525767A/ja

2018-09-27 Publication of JP2017525767A5 publication Critical patent/JP2017525767A5/ja

2020-10-07 Application granted granted Critical

2020-10-07 Publication of JP6766047B2 publication Critical patent/JP6766047B2/ja

Status Active legal-status Critical Current

2035-08-20 Anticipated expiration legal-status Critical

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150000003839 salts Chemical class 0.000 claims description 77
150000001875 compounds Chemical class 0.000 claims description 69
125000000217 alkyl group Chemical group 0.000 claims description 26
150000004820 halides Chemical class 0.000 claims description 15
125000001424 substituent group Chemical group 0.000 claims description 13
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims description 9
229910052799 carbon Inorganic materials 0.000 claims description 7
125000004432 carbon atom Chemical group C* 0.000 claims description 7
239000002537 cosmetic Substances 0.000 claims description 7
VILAVOFMIJHSJA-UHFFFAOYSA-N dicarbon monoxide Chemical group [C]=C=O VILAVOFMIJHSJA-UHFFFAOYSA-N 0.000 claims description 7
125000001188 haloalkyl group Chemical group 0.000 claims description 6
125000006570 (C5-C6) heteroaryl group Chemical group 0.000 claims description 5
125000001072 heteroaryl group Chemical group 0.000 claims description 4
230000002265 prevention Effects 0.000 claims description 4
230000036548 skin texture Effects 0.000 claims description 4
108010050808 Procollagen Proteins 0.000 claims description 2
206010040829 Skin discolouration Diseases 0.000 claims description 2
230000037319 collagen production Effects 0.000 claims description 2
238000004519 manufacturing process Methods 0.000 claims description 2
230000037370 skin discoloration Effects 0.000 claims description 2
230000037394 skin elasticity Effects 0.000 claims description 2
230000036558 skin tension Effects 0.000 claims description 2
230000001225 therapeutic effect Effects 0.000 claims description 2
230000000699 topical effect Effects 0.000 claims description 2
230000037303 wrinkles Effects 0.000 claims description 2
238000000034 method Methods 0.000 description 54
LMBFAGIMSUYTBN-MPZNNTNKSA-N teixobactin Chemical compound C([C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H]1C(N[C@@H](C)C(=O)N[C@@H](C[C@@H]2NC(=N)NC2)C(=O)N[C@H](C(=O)O[C@H]1C)[C@@H](C)CC)=O)NC)C1=CC=CC=C1 LMBFAGIMSUYTBN-MPZNNTNKSA-N 0.000 description 9
VLPNJFDOGNOZIG-UHFFFAOYSA-N Cc(cccc1)c1C(CCC(c(cc1)ccc1O)=O)=O Chemical compound Cc(cccc1)c1C(CCC(c(cc1)ccc1O)=O)=O VLPNJFDOGNOZIG-UHFFFAOYSA-N 0.000 description 1
206010064729 Dark circles under eyes Diseases 0.000 description 1
238000007665 sagging Methods 0.000 description 1

JP2017529598A 2014-08-20 2015-08-20 加齢皮膚およびしわの処置用および予防用のγ−ジケトン Active JP6766047B2 (ja)