JP2017522879A5 - - Google Patents
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- JP2017522879A5 JP2017522879A5 JP2017503488A JP2017503488A JP2017522879A5 JP 2017522879 A5 JP2017522879 A5 JP 2017522879A5 JP 2017503488 A JP2017503488 A JP 2017503488A JP 2017503488 A JP2017503488 A JP 2017503488A JP 2017522879 A5 JP2017522879 A5 JP 2017522879A5
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNPCT/CN2014/082602 | 2014-07-21 | ||
| CN2014082602 | 2014-07-21 | ||
| CNPCT/CN2014/090500 | 2014-11-06 | ||
| CN2014090500 | 2014-11-06 | ||
| PCT/US2015/041337 WO2016014535A1 (en) | 2014-07-21 | 2015-07-21 | Treatment of cancer using a cll-1 chimeric antigen receptor |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020121501A Division JP2020185001A (ja) | 2014-07-21 | 2020-07-15 | Ｃｌｌ−１キメラ抗原受容体を使用した癌の処置 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017522879A JP2017522879A (ja) | 2017-08-17 |
| JP2017522879A5 true JP2017522879A5 (he) | 2018-08-30 |
| JP6736540B2 JP6736540B2 (ja) | 2020-08-05 |
Family
ID=53761606
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017503488A Expired - Fee Related JP6736540B2 (ja) | 2014-07-21 | 2015-07-21 | Ｃｌｌ−１キメラ抗原受容体を使用した癌の処置 |
| JP2020121501A Pending JP2020185001A (ja) | 2014-07-21 | 2020-07-15 | Ｃｌｌ−１キメラ抗原受容体を使用した癌の処置 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020121501A Pending JP2020185001A (ja) | 2014-07-21 | 2020-07-15 | Ｃｌｌ−１キメラ抗原受容体を使用した癌の処置 |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US10568947B2 (he) |
| EP (1) | EP3171882A1 (he) |
| JP (2) | JP6736540B2 (he) |
| KR (1) | KR20170037625A (he) |
| CN (1) | CN107109420A (he) |
| AR (1) | AR101829A1 (he) |
| AU (2) | AU2015292811B2 (he) |
| BR (1) | BR112017000939A2 (he) |
| CA (1) | CA2955465A1 (he) |
| CO (1) | CO2017000506A2 (he) |
| IL (1) | IL250116B (he) |
| MX (1) | MX2017001013A (he) |
| RU (1) | RU2741120C2 (he) |
| SG (2) | SG10201913782UA (he) |
| TW (1) | TWI718992B (he) |
| WO (1) | WO2016014535A1 (he) |
Families Citing this family (126)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2708032C2 (ru) | 2013-02-20 | 2019-12-03 | Новартис Аг | ЛЕЧЕНИЕ РАКА С ИСПОЛЬЗОВАНИЕМ ХИМЕРНОГО АНТИГЕНСПЕЦИФИЧЕСКОГО РЕЦЕПТОРА НА ОСНОВЕ ГУМАНИЗИРОВАННОГО АНТИТЕЛА ПРОТИВ EGFRvIII |
| TW201446794A (zh) | 2013-02-20 | 2014-12-16 | Novartis Ag | 利用抗－ｃｄ１２３嵌合抗原受體工程化ｔ細胞之初級人類白血病有效靶向 |
| EP2970426B1 (en) | 2013-03-15 | 2019-08-28 | Michael C. Milone | Targeting cytotoxic cells with chimeric receptors for adoptive immunotherapy |
| UY35468A (es) | 2013-03-16 | 2014-10-31 | Novartis Ag | Tratamiento de cáncer utilizando un receptor quimérico de antígeno anti-cd19 |
| AU2014348657A1 (en) * | 2013-11-13 | 2016-05-19 | Novartis Ag | mTOR inhibitors for enhancing the immune response |
| US10640569B2 (en) | 2013-12-19 | 2020-05-05 | Novartis Ag | Human mesothelin chimeric antigen receptors and uses thereof |
| EP3087101B1 (en) | 2013-12-20 | 2024-06-05 | Novartis AG | Regulatable chimeric antigen receptor |
| WO2015112626A1 (en) | 2014-01-21 | 2015-07-30 | June Carl H | Enhanced antigen presenting ability of car t cells by co-introduction of costimulatory molecules |
| IL280215B (he) | 2014-04-07 | 2022-07-01 | Novartis Ag | טיפול בסרטן על ידי שימוש באנטיגן קולטן כימרי (car) כנגד cd19 |
| JP6831777B2 (ja) | 2014-07-21 | 2021-02-17 | ノバルティス アーゲー | Ｃｄ３３キメラ抗原受容体を使用する癌の処置 |
| WO2016014553A1 (en) | 2014-07-21 | 2016-01-28 | Novartis Ag | Sortase synthesized chimeric antigen receptors |
| RU2751660C2 (ru) | 2014-07-21 | 2021-07-15 | Новартис Аг | Лечение злокачественного новообразования с использованием гуманизированного химерного антигенного рецептора против всма |
| RU2741120C2 (ru) | 2014-07-21 | 2021-01-22 | Новартис Аг | Лечение рака с использованием химерного антигенного рецептора cll-1 |
| CN107108744B (zh) | 2014-08-19 | 2020-09-25 | 诺华股份有限公司 | 抗cd123嵌合抗原受体(car)用于癌症治疗 |
| CA2961636A1 (en) | 2014-09-17 | 2016-03-24 | Boris ENGELS | Targeting cytotoxic cells with chimeric receptors for adoptive immunotherapy |
| CN106973568B (zh) | 2014-10-08 | 2021-07-23 | 诺华股份有限公司 | 预测针对嵌合抗原受体疗法的治疗应答性的生物标志及其用途 |
| SG11201705293WA (en) | 2014-12-29 | 2017-07-28 | Novartis Ag | Methods of making chimeric antigen receptor-expressing cells |
| WO2016115482A1 (en) * | 2015-01-16 | 2016-07-21 | Novartis Pharma Ag | Phosphoglycerate kinase 1 (pgk) promoters and methods of use for expressing chimeric antigen receptor |
| ES2842212T3 (es) * | 2015-01-26 | 2021-07-13 | Cellectis | Receptores de antígenos quiméricos monocatenarios específicos anti-CLL1 (scCAR) para inmunoterapia contra el cáncer |
| US11161907B2 (en) | 2015-02-02 | 2021-11-02 | Novartis Ag | Car-expressing cells against multiple tumor antigens and uses thereof |
| KR20170120701A (ko) | 2015-03-05 | 2017-10-31 | 프레드 헛친슨 켄서 리서치 센터 | 면역조절 융합 단백질 및 그 용도 |
| IL303972A (he) | 2015-04-08 | 2023-08-01 | Novartis Ag | טיפולי cd20, טיפולי cd22 וטיפולים משולבים עם תא מבטא קולטן אנטיגני כימרי cd19 |
| ES2948133T3 (es) | 2015-04-17 | 2023-08-31 | Novartis Ag | Métodos para mejorar la eficacia y expansión de células que expresan un receptor de antígeno quimérico |
| CN107847491A (zh) | 2015-05-20 | 2018-03-27 | 诺华公司 | 依维莫司(everolimus)与达托里昔布(dactolisib)的医药组合 |
| US20180171298A1 (en) | 2015-06-30 | 2018-06-21 | Cellectis | Methods for improving functionality in nk cell by gene inactivation using specific endonuclease |
| JP7146632B2 (ja) | 2015-07-21 | 2022-10-04 | ノバルティス アーゲー | 免疫細胞の有効性および増大を改善する方法 |
| WO2017027392A1 (en) | 2015-08-07 | 2017-02-16 | Novartis Ag | Treatment of cancer using chimeric cd3 receptor proteins |
| CN116334205A (zh) | 2015-09-03 | 2023-06-27 | 诺华股份有限公司 | 预测细胞因子释放综合征的生物标志物 |
| MA44140A (fr) | 2015-12-22 | 2021-05-19 | Dana Farber Cancer Inst Inc | Récepteur d'antigène chimérique (car) contre la mésothéline et anticorps contre l'inhibiteur de pd-l1 pour une utilisation combinée dans une thérapie anticancéreuse |
| SG11201805451TA (en) | 2015-12-30 | 2018-07-30 | Novartis Ag | Immune effector cell therapies with enhanced efficacy |
| MA55746A (fr) * | 2016-01-21 | 2022-03-02 | Novartis Ag | Molécules multispécifiques ciblant cll-1 |
| SG11201807489PA (en) | 2016-03-04 | 2018-09-27 | Novartis Ag | Cells expressing multiple chimeric antigen receptor (car) molecules and uses therefore |
| EP3432924A1 (en) | 2016-03-23 | 2019-01-30 | Novartis AG | Cell secreted minibodies and uses thereof |
| KR20230148844A (ko) * | 2016-03-29 | 2023-10-25 | 유니버시티 오브 써던 캘리포니아 | 암을 표적하는 키메라 항원 수용체 |
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2015
- 2015-07-21 RU RU2017105161A patent/RU2741120C2/ru active
- 2015-07-21 EP EP15744448.0A patent/EP3171882A1/en not_active Withdrawn
- 2015-07-21 US US14/805,075 patent/US10568947B2/en active Active
- 2015-07-21 TW TW104123638A patent/TWI718992B/zh not_active IP Right Cessation
- 2015-07-21 AR ARP150102310A patent/AR101829A1/es unknown
- 2015-07-21 SG SG10201913782UA patent/SG10201913782UA/en unknown
- 2015-07-21 WO PCT/US2015/041337 patent/WO2016014535A1/en active Application Filing
- 2015-07-21 CA CA2955465A patent/CA2955465A1/en not_active Abandoned
- 2015-07-21 CN CN201580050589.9A patent/CN107109420A/zh active Pending
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- 2015-07-21 JP JP2017503488A patent/JP6736540B2/ja not_active Expired - Fee Related
- 2015-07-21 KR KR1020177004392A patent/KR20170037625A/ko not_active Application Discontinuation
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- 2015-07-21 BR BR112017000939A patent/BR112017000939A2/pt not_active IP Right Cessation
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2019
- 2019-12-27 US US16/728,557 patent/US20200215171A1/en not_active Abandoned
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