|
US9745548B2
(en)
|
2012-03-15 |
2017-08-29 |
Flodesign Sonics, Inc. |
Acoustic perfusion devices
|
|
US9950282B2
(en)
|
2012-03-15 |
2018-04-24 |
Flodesign Sonics, Inc. |
Electronic configuration and control for acoustic standing wave generation
|
|
US10322949B2
(en)
|
2012-03-15 |
2019-06-18 |
Flodesign Sonics, Inc. |
Transducer and reflector configurations for an acoustophoretic device
|
|
US10704021B2
(en)
|
2012-03-15 |
2020-07-07 |
Flodesign Sonics, Inc. |
Acoustic perfusion devices
|
|
US10967298B2
(en)
|
2012-03-15 |
2021-04-06 |
Flodesign Sonics, Inc. |
Driver and control for variable impedence load
|
|
US10689609B2
(en)
|
2012-03-15 |
2020-06-23 |
Flodesign Sonics, Inc. |
Acoustic bioreactor processes
|
|
US9458450B2
(en)
|
2012-03-15 |
2016-10-04 |
Flodesign Sonics, Inc. |
Acoustophoretic separation technology using multi-dimensional standing waves
|
|
US9752113B2
(en)
|
2012-03-15 |
2017-09-05 |
Flodesign Sonics, Inc. |
Acoustic perfusion devices
|
|
US10737953B2
(en)
|
2012-04-20 |
2020-08-11 |
Flodesign Sonics, Inc. |
Acoustophoretic method for use in bioreactors
|
|
EP4282419A1
(en)
|
2012-12-20 |
2023-11-29 |
Purdue Research Foundation |
Chimeric antigen receptor-expressing t cells as anti-cancer therapeutics
|
|
EP3974520A1
(en)
|
2013-05-14 |
2022-03-30 |
Board of Regents, The University of Texas System |
Human application of engineered chimeric antigen receptor (car) t-cells
|
|
WO2014190273A1
(en)
|
2013-05-24 |
2014-11-27 |
Board Of Regents, The University Of Texas System |
Chimeric antigen receptor-targeting monoclonal antibodies
|
|
US9745569B2
(en)
|
2013-09-13 |
2017-08-29 |
Flodesign Sonics, Inc. |
System for generating high concentration factors for low cell density suspensions
|
|
CA2935960C
(en)
|
2014-01-08 |
2023-01-10 |
Bart Lipkens |
Acoustophoresis device with dual acoustophoretic chamber
|
|
CA3190002A1
(en)
|
2014-02-14 |
2015-08-20 |
Board Of Regents, The University Of Texas System |
Chimeric antigen receptors and methods of making
|
|
IL313845A
(en)
|
2014-04-23 |
2024-08-01 |
Juno Therapeutics Inc |
Methods for enriching or producing immune cell populations for adoptive therapy
|
|
US9744483B2
(en)
|
2014-07-02 |
2017-08-29 |
Flodesign Sonics, Inc. |
Large scale acoustic separation device
|
|
GB201506423D0
(en)
|
2015-04-15 |
2015-05-27 |
Tc Biopharm Ltd |
Gamma delta T cells and uses thereof
|
|
FR3026744B1
(fr)
|
2014-10-06 |
2024-04-19 |
Hopitaux Paris Assist Publique |
Methode de generation de progeniteurs de cellules t
|
|
WO2016073629A1
(en)
|
2014-11-05 |
2016-05-12 |
Board Of Regents, The University Of Texas System |
Chimeric antigen receptors (car) to selectively target protein complexes
|
|
CA3008162A1
(en)
|
2014-12-15 |
2016-06-23 |
The Regents Of The University Of California |
Bispecific or-gate chimeric antigen receptor responsive to cd19 and cd20
|
|
EP3804741A3
(en)
|
2015-02-24 |
2021-07-14 |
Board of Regents, The University of Texas System |
Selection methods for genetically-modified t cells
|
|
CA2977818A1
(en)
|
2015-03-11 |
2016-09-15 |
Board Of Regents, The University Of Texas System |
Transposase polypeptides and uses thereof
|
|
US11377651B2
(en)
|
2016-10-19 |
2022-07-05 |
Flodesign Sonics, Inc. |
Cell therapy processes utilizing acoustophoresis
|
|
US11021699B2
(en)
|
2015-04-29 |
2021-06-01 |
FioDesign Sonics, Inc. |
Separation using angled acoustic waves
|
|
US11708572B2
(en)
|
2015-04-29 |
2023-07-25 |
Flodesign Sonics, Inc. |
Acoustic cell separation techniques and processes
|
|
GB201507368D0
(en)
|
2015-04-30 |
2015-06-17 |
Ucl Business Plc |
Cell
|
|
US11459540B2
(en)
|
2015-07-28 |
2022-10-04 |
Flodesign Sonics, Inc. |
Expanded bed affinity selection
|
|
US11474085B2
(en)
|
2015-07-28 |
2022-10-18 |
Flodesign Sonics, Inc. |
Expanded bed affinity selection
|
|
GB2557123B
(en)
|
2015-07-31 |
2021-11-03 |
Univ Minnesota |
Modified cells and methods of therapy
|
|
EP3328994A4
(en)
*
|
2015-07-31 |
2019-04-17 |
Memorial Sloan-Kettering Cancer Center |
CD56-Faced Antigen-Binding Proteins and Uses Thereof
|
|
KR20180042449A
(ko)
|
2015-09-15 |
2018-04-25 |
보드 오브 리전츠, 더 유니버시티 오브 텍사스 시스템 |
T 세포 수용체(tcr) 결합 항체 및 이의 용도
|
|
EP3368075B1
(en)
|
2015-10-27 |
2020-01-29 |
Board of Regents, The University of Texas System |
Chimeric antigen receptor molecules and uses thereof
|
|
CN108779174B
(zh)
*
|
2015-11-04 |
2022-11-29 |
希望之城公司 |
靶向her2的嵌合抗原受体
|
|
EP3373941A4
(en)
*
|
2015-11-09 |
2019-03-27 |
Aperisys, Inc. |
MODIFIED IMMUNOCELLS AND USES THEREOF
|
|
WO2017132535A1
(en)
|
2016-01-28 |
2017-08-03 |
The Regents Of The University Of California |
Methods for selectively expanding and enriching cells transduced with chimeric antigen receptors and treating hiv infection
|
|
BR112018015836A2
(en)
|
2016-02-05 |
2018-12-26 |
City Of Hope |
engineered t-cell administration for central nervous system cancer treatment
|
|
US12144850B2
(en)
|
2016-04-08 |
2024-11-19 |
Purdue Research Foundation |
Methods and compositions for car T cell therapy
|
|
WO2017184968A1
(en)
*
|
2016-04-22 |
2017-10-26 |
Kura Oncology, Inc. |
Methods of selecting cancer patients for treatment with farnesyltransferase inhibitors
|
|
US11085035B2
(en)
|
2016-05-03 |
2021-08-10 |
Flodesign Sonics, Inc. |
Therapeutic cell washing, concentration, and separation utilizing acoustophoresis
|
|
US11214789B2
(en)
|
2016-05-03 |
2022-01-04 |
Flodesign Sonics, Inc. |
Concentration and washing of particles with acoustics
|
|
CA3026640A1
(en)
*
|
2016-06-06 |
2017-12-14 |
City Of Hope |
Baff-r targeted chimeric antigen receptor-modified t-cells and uses thereof
|
|
WO2017214569A1
(en)
*
|
2016-06-09 |
2017-12-14 |
Regents Of The University Of Minnesota |
Genome-edited nk cell and methods of making and using
|
|
CN107523547A
(zh)
*
|
2016-06-20 |
2017-12-29 |
上海细胞治疗研究院 |
一种高效稳定表达抑制性抗体的car‑t细胞及其用途
|
|
US11583555B2
(en)
|
2016-06-24 |
2023-02-21 |
University of Pittsburgh—of the Commonwealth System of Higher Education |
Genetic re-engineering of immune cells to improve metabolic fitness for immunotherapy
|
|
CN107663240B
(zh)
*
|
2016-07-29 |
2021-01-12 |
中国人民解放军第四军医大学 |
高度糖基化cea特异性结合的单链抗体及其在检测和治疗上的应用
|
|
WO2018044866A1
(en)
|
2016-08-30 |
2018-03-08 |
Memorial Sloan Kettering Cancer Center |
Immune cell compositions and methods of use for treating viral and other infections
|
|
CN110494543A
(zh)
|
2016-10-19 |
2019-11-22 |
弗洛设计声能学公司 |
通过声学的亲和细胞提取
|
|
CN110121505B
(zh)
|
2016-12-28 |
2023-08-01 |
株式会社绿十字细胞治疗 |
嵌合抗原受体和表达其的自然杀伤细胞
|
|
EP4067482A1
(en)
|
2017-02-13 |
2022-10-05 |
Assistance Publique - Hôpitaux de Paris |
Method for generating t cells progenitors
|
|
ES3010559T3
(en)
|
2017-02-28 |
2025-04-03 |
Endocyte Inc |
Compositions and methods for car t cell therapy
|
|
US11629340B2
(en)
|
2017-03-03 |
2023-04-18 |
Obsidian Therapeutics, Inc. |
DHFR tunable protein regulation
|
|
US11166985B2
(en)
|
2017-05-12 |
2021-11-09 |
Crispr Therapeutics Ag |
Materials and methods for engineering cells and uses thereof in immuno-oncology
|
|
BR112019023608A2
(pt)
|
2017-05-12 |
2020-05-26 |
Crispr Therapeutics Ag |
Materiais e métodos para células manipuladas e seus usos em imuno-oncologia
|
|
CN107099603A
(zh)
*
|
2017-05-31 |
2017-08-29 |
成都克里斯博生物科技有限公司 |
肿瘤免疫t细胞检测试剂盒和检测方法
|
|
GB201709203D0
(en)
|
2017-06-09 |
2017-07-26 |
Autolus Ltd |
Antigen-binding domain
|
|
WO2019014456A1
(en)
*
|
2017-07-12 |
2019-01-17 |
The Board Of Trustees Of The Leland Stanford Junior University |
COMPOSITIONS AND METHODS FOR THE TREATMENT OF CANCERS HAVING A MUTATION H3K27M
|
|
EP3658163A4
(en)
*
|
2017-07-25 |
2021-08-04 |
Board Of Regents, The University Of Texas System |
NOVEL CHIMERIC ANTIGEN RECEPTORS AND USES THEREOF
|
|
TWI676483B
(zh)
*
|
2017-08-06 |
2019-11-11 |
強普生技股份有限公司 |
醫藥套組及其用途
|
|
CN107287165A
(zh)
*
|
2017-08-23 |
2017-10-24 |
湖南开启时代生物科技有限责任公司 |
一种car‑t细胞的制备方法
|
|
US20200261502A1
(en)
*
|
2017-09-08 |
2020-08-20 |
Carsgen Therapeutics Co., Ltd. |
Genetically engineered t cell and application thereof
|
|
MA50651A
(fr)
*
|
2017-09-29 |
2020-08-05 |
Us Health |
Récepteurs de lymphocytes t reconnaissant p53 mutée
|
|
CN107488738B
(zh)
*
|
2017-10-12 |
2020-04-28 |
中国医学科学院肿瘤医院 |
一种预测乳腺癌对曲妥珠单抗联合化疗治疗敏感性的生物标志物
|
|
EP3707165A4
(en)
|
2017-11-07 |
2021-09-08 |
The Board of Regents of The University of Texas System |
LILRB4 TARGETING WITH CAR-T OR CAR-NK CELLS IN THE TREATMENT OF CANCER
|
|
EP3712178A4
(en)
|
2017-11-14 |
2021-08-11 |
Green Cross Lab Cell Corporation |
ANTI-HER2 ANTIBODIES OR ANTIGIBODY FRAGMENT THEREOF AND CHIMERAIR ANTIGEN RECEPTOR WITH IT
|
|
US11649294B2
(en)
|
2017-11-14 |
2023-05-16 |
GC Cell Corporation |
Anti-HER2 antibody or antigen-binding fragment thereof, and chimeric antigen receptor comprising same
|
|
CN111373261B
(zh)
*
|
2017-11-20 |
2024-06-14 |
尤利乌斯·马克西米利安维尔茨堡大学 |
Cd19 cart细胞可清除表达极低水平cd19的骨髓瘤细胞
|
|
CU24558B1
(es)
*
|
2017-11-28 |
2021-12-08 |
Ct Inmunologia Molecular |
Anticuerpos monoclonales que reconocen al receptor del factor de crecimiento epidérmico y sus fragmentos derivados
|
|
CN108070033A
(zh)
*
|
2017-12-12 |
2018-05-25 |
武汉波睿达生物科技有限公司 |
一种3bnc-car分子的构建及其在杀灭hiv-1感染细胞中的应用
|
|
SG11202003907WA
(en)
|
2017-12-14 |
2020-05-28 |
Flodesign Sonics Inc |
Acoustic transducer drive and controller
|
|
BR112020011893A2
(pt)
|
2017-12-15 |
2020-11-24 |
The Board Of Trustees Of The Leland Stanford Junior University |
composições e métodos para inibir a exaustão de células t
|
|
CN111683971A
(zh)
*
|
2017-12-23 |
2020-09-18 |
宇越生医科技股份有限公司 |
医药重组受体组成物及方法
|
|
CA3086832A1
(en)
|
2018-01-03 |
2019-07-11 |
Qu Biologics Inc. |
Innate targeting of adoptive cellular therapies
|
|
US11965191B2
(en)
|
2018-01-18 |
2024-04-23 |
California Institute Of Technology |
Programmable protein circuits in living cells
|
|
US11311576B2
(en)
*
|
2018-01-22 |
2022-04-26 |
Seattle Children's Hospital |
Methods of use for CAR T cells
|
|
US11696943B2
(en)
|
2018-01-23 |
2023-07-11 |
Vanderbilt University |
Self-antigen specific T-cells as vaccines for augmenting engraftment and stability of autologous transfer
|
|
WO2019156795A1
(en)
|
2018-02-06 |
2019-08-15 |
Seattle Children's Hospital (dba Seattle Children's Research Institute) |
Fluorescein-specific cars exhibiting optimal t cell function against fl-ple labelled tumors
|
|
CA3091674A1
(en)
|
2018-02-23 |
2019-08-29 |
Endocyte, Inc. |
Sequencing method for car t cell therapy
|
|
MX2020009359A
(es)
*
|
2018-03-08 |
2021-01-29 |
Rubius Therapeutics Inc |
Sistemas de celulas terapeuticas y metodos para el tratamiento de cancer y enfermedades infecciosas.
|
|
WO2019204664A2
(en)
*
|
2018-04-19 |
2019-10-24 |
Apdn (B.V.I), Inc. |
Engineered lymphocyte compositions, methods and systems
|
|
EP3790629A1
(en)
|
2018-05-11 |
2021-03-17 |
CRISPR Therapeutics AG |
Methods and compositions for treating cancer
|
|
AU2019301070B2
(en)
*
|
2018-07-09 |
2025-09-11 |
Precigen, Inc. |
Fusion constructs and methods of using thereof
|
|
SG11202100616VA
(en)
*
|
2018-08-07 |
2021-03-30 |
Purdue Research Foundation |
Rejuvenation of car t cell
|
|
CN110862967A
(zh)
*
|
2018-08-27 |
2020-03-06 |
天津天锐生物科技有限公司 |
一种不依赖细胞因子培养的自然杀伤细胞系silk-nk
|
|
EP3844180A4
(en)
|
2018-08-31 |
2022-07-20 |
California Institute of Technology |
Synthetic protein circuits detecting signal transducer activity
|
|
WO2020051493A1
(en)
*
|
2018-09-07 |
2020-03-12 |
Unum Therapeutics Inc. |
Chimeric receptor polypeptides in combination with trans metabolism molecules modulating intracellular lactate concentrations and therapeutic uses thereof
|
|
JP2022512594A
(ja)
*
|
2018-10-05 |
2022-02-07 |
ザンクト アンナ キンダークレプスフォルシュング |
キメラ抗原受容体(car)の群
|
|
US12331320B2
(en)
|
2018-10-10 |
2025-06-17 |
The Research Foundation For The State University Of New York |
Genome edited cancer cell vaccines
|
|
CA3120563A1
(en)
|
2018-11-26 |
2020-06-04 |
Nkarta, Inc. |
Methods for the simultaneous expansion of multiple immune cell types, related compositions and uses of same in cancer immunotherapy
|
|
US11667676B2
(en)
|
2019-01-10 |
2023-06-06 |
California Institute Of Technology |
Synthetic system for tunable thresholding of protein signals
|
|
CA3127673A1
(en)
|
2019-01-25 |
2020-07-30 |
The Trustees Of The University Of Pennsylvania |
Compositions and methods for targeting mutant ras
|
|
CA3130671A1
(en)
*
|
2019-02-07 |
2020-08-13 |
Board Of Regents, The University Of Texas Systems |
Glucuronoxylomannan (gxm) receptor chimeric antigen receptors and use thereof
|
|
KR20210124236A
(ko)
*
|
2019-02-08 |
2021-10-14 |
비온테크 쎌 & 제네 테라피스 게엠베하 |
Car-조작된 t 세포 및 사이토카인을 수반한 치료
|
|
EP3924467A1
(en)
|
2019-02-15 |
2021-12-22 |
Editas Medicine, Inc. |
Modified natural killer (nk) cells for immunotherapy
|
|
EP3927738A1
(en)
|
2019-02-20 |
2021-12-29 |
City of Hope |
Baff-r/cd19 targeted chimeric antigen receptor-modified t cells and use thereof
|
|
WO2020180882A1
(en)
|
2019-03-05 |
2020-09-10 |
Nkarta, Inc. |
Cd19-directed chimeric antigen receptors and uses thereof in immunotherapy
|
|
AU2020267057A1
(en)
|
2019-04-30 |
2021-11-18 |
Crispr Therapeutics Ag |
Allogeneic cell therapy of B cell malignancies using genetically engineered T cells targeting CD19
|
|
MX2021015125A
(es)
*
|
2019-06-07 |
2022-04-06 |
Juno Therapeutics Inc |
Cultivo automatizado de celulas t.
|
|
JP2022535138A
(ja)
*
|
2019-06-07 |
2022-08-04 |
ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア |
Cd28および4-1bbに個々に連結したデュアルcarを発現するt細胞
|
|
MX2022002747A
(es)
|
2019-09-10 |
2022-04-06 |
Obsidian Therapeutics Inc |
Proteinas de fusion de ca2-il15 para regulacion ajustable.
|
|
AU2020379848A1
(en)
*
|
2019-11-06 |
2022-05-19 |
Baylor College Of Medicine |
Method for producing cytotoxic effector memory T cells for T-cell treatment of cancer
|
|
US20230000916A1
(en)
*
|
2019-11-27 |
2023-01-05 |
The Trustees Of The University Of Pennsylvania |
Anti-cd3 scfv and cytokine producing artificial antigen presenting cells
|
|
WO2021119489A1
(en)
*
|
2019-12-11 |
2021-06-17 |
A2 Biotherapeutics, Inc. |
Lilrb1-based chimeric antigen receptor
|
|
KR20220163940A
(ko)
|
2020-02-04 |
2022-12-12 |
시애틀 칠드런즈 호스피탈 디/비/에이 시애틀 칠드런즈 리서치 인스티튜트 |
항-디니트로페놀 키메라 항원 수용체
|
|
US20230138428A1
(en)
*
|
2020-02-25 |
2023-05-04 |
Quell Therapeutics Limited |
Chimeric receptors for use in engineered cells
|
|
CN111253493B
(zh)
*
|
2020-03-05 |
2021-03-23 |
武汉科技大学 |
一种靶向hiv病毒囊膜双位点的嵌合抗原受体及其表达载体和应用
|
|
US12264190B2
(en)
*
|
2020-04-24 |
2025-04-01 |
Astrazeneca Ab |
Compositions and methods of treating cancer with chimeric antigen receptors
|
|
CN113913459A
(zh)
*
|
2020-07-09 |
2022-01-11 |
杭州优凯瑞医药科技有限公司 |
一种应用非病毒方法制备高纯度嵌合抗原受体修饰的t细胞的方法及其应用
|
|
IL299764A
(en)
|
2020-07-10 |
2023-03-01 |
Precigen Inc |
Fusion constructs and methods for using them
|
|
KR102605723B1
(ko)
*
|
2020-11-11 |
2023-11-24 |
한국과학기술원 |
키메라 항원 수용체를 위한 타깃 항원 발굴 방법 및 분석 장치
|
|
CN114716548B
(zh)
*
|
2021-01-05 |
2024-11-05 |
(株)爱恩德生物 |
抗-fgfr3抗体及其用途
|
|
US20240327889A1
(en)
*
|
2021-04-05 |
2024-10-03 |
Victor TETS |
Regulation of cells and organisms
|
|
IL307417A
(en)
*
|
2021-04-08 |
2023-12-01 |
Artiva Biotherapeutics Inc |
Chimeric antigen receptor comprising an anti-her2 antibody or antigen-binding fragment thereof and natural killer cells comprising the same
|
|
AU2022299551A1
(en)
|
2021-06-23 |
2024-01-18 |
Editas Medicine, Inc. |
Engineered cells for therapy
|
|
EP4130028A1
(en)
|
2021-08-03 |
2023-02-08 |
Rhazes Therapeutics Ltd |
Engineered tcr complex and methods of using same
|
|
CA3226947A1
(en)
|
2021-08-03 |
2023-02-09 |
Muhammad YASSIN |
Engineered tcr complex and methods of using same
|
|
EP4722239A2
(en)
*
|
2021-08-20 |
2026-04-08 |
Christopher E. Rudd |
Compositions and methods for anti-virus chimeric antigen receptor
|
|
KR20250005097A
(ko)
|
2022-04-08 |
2025-01-09 |
페이트 세러퓨틱스, 인코포레이티드 |
고형 종양 표적화 골격을 갖는 세포 및 이의 용도
|
|
JP7707304B2
(ja)
*
|
2022-04-08 |
2025-07-14 |
フェイト セラピューティクス,インコーポレイティド |
腫瘍標的化のためのキメラ抗原受容体
|
|
CN115873803B
(zh)
*
|
2022-11-28 |
2025-06-17 |
上海恩凯细胞技术有限公司 |
提高nk细胞存活和抗肿瘤活性的方法及应用
|
|
WO2025106453A1
(en)
*
|
2023-11-13 |
2025-05-22 |
California Institute Of Technology |
Synpoptosis circuits for programmable cell death control
|
|
CN119080932A
(zh)
*
|
2024-09-02 |
2024-12-06 |
浙江大学 |
靶向表皮生长因子受体耐药性突变体的西妥昔单抗变体
|