|
WO2009126789A2
(en)
|
2008-04-09 |
2009-10-15 |
Maxcyte, Inc. |
Engineering and delivery of therapeutic compositions of freshly isolated cells
|
|
JP6251570B2
(ja)
|
2010-09-21 |
2017-12-20 |
アルター・バイオサイエンス・コーポレーション |
多量体il−15可溶性融合分子並びにその製造及び使用方法
|
|
US10704021B2
(en)
|
2012-03-15 |
2020-07-07 |
Flodesign Sonics, Inc. |
Acoustic perfusion devices
|
|
US9752113B2
(en)
|
2012-03-15 |
2017-09-05 |
Flodesign Sonics, Inc. |
Acoustic perfusion devices
|
|
US9745548B2
(en)
|
2012-03-15 |
2017-08-29 |
Flodesign Sonics, Inc. |
Acoustic perfusion devices
|
|
US10967298B2
(en)
|
2012-03-15 |
2021-04-06 |
Flodesign Sonics, Inc. |
Driver and control for variable impedence load
|
|
US10322949B2
(en)
|
2012-03-15 |
2019-06-18 |
Flodesign Sonics, Inc. |
Transducer and reflector configurations for an acoustophoretic device
|
|
US9458450B2
(en)
|
2012-03-15 |
2016-10-04 |
Flodesign Sonics, Inc. |
Acoustophoretic separation technology using multi-dimensional standing waves
|
|
US9950282B2
(en)
|
2012-03-15 |
2018-04-24 |
Flodesign Sonics, Inc. |
Electronic configuration and control for acoustic standing wave generation
|
|
US10689609B2
(en)
|
2012-03-15 |
2020-06-23 |
Flodesign Sonics, Inc. |
Acoustic bioreactor processes
|
|
US10737953B2
(en)
|
2012-04-20 |
2020-08-11 |
Flodesign Sonics, Inc. |
Acoustophoretic method for use in bioreactors
|
|
EP2934532B1
(en)
|
2012-12-20 |
2019-10-23 |
Purdue Research Foundation |
Chimeric antigen receptor-expressing t cells as anti-cancer therapeutics
|
|
SG11201505858VA
(en)
|
2013-01-28 |
2015-09-29 |
St Jude Childrens Res Hospital |
A chimeric receptor with nkg2d specificity for use in cell therapy against cancer and infectious disease
|
|
EP3569313A1
(en)
|
2013-03-15 |
2019-11-20 |
GPB Scientific, LLC |
On-chip microfluidic processing of particles
|
|
US10324011B2
(en)
|
2013-03-15 |
2019-06-18 |
The Trustees Of Princeton University |
Methods and devices for high throughput purification
|
|
US20150064153A1
(en)
|
2013-03-15 |
2015-03-05 |
The Trustees Of Princeton University |
High efficiency microfluidic purification of stem cells to improve transplants
|
|
EP2997134B1
(en)
*
|
2013-05-14 |
2020-06-24 |
Board of Regents, The University of Texas System |
Human application of engineered chimeric antigen receptor (car) t-cells
|
|
EP3004168A4
(en)
|
2013-05-24 |
2017-03-01 |
Board of Regents, The University of Texas System |
Chimeric antigen receptor-targeting monoclonal antibodies
|
|
US9745569B2
(en)
|
2013-09-13 |
2017-08-29 |
Flodesign Sonics, Inc. |
System for generating high concentration factors for low cell density suspensions
|
|
WO2015105955A1
(en)
|
2014-01-08 |
2015-07-16 |
Flodesign Sonics, Inc. |
Acoustophoresis device with dual acoustophoretic chamber
|
|
US11028143B2
(en)
|
2014-01-21 |
2021-06-08 |
Novartis Ag |
Enhanced antigen presenting ability of RNA CAR T cells by co-introduction of costimulatory molecules
|
|
WO2015120187A1
(en)
|
2014-02-05 |
2015-08-13 |
The University Of Chicago |
Chimeric antigen receptors recognizing cancer-spevific tn glycopeptide variants
|
|
MX369513B
(es)
|
2014-02-14 |
2019-11-11 |
Univ Texas |
Receptores de antígenos quiméricos y métodos de realización.
|
|
JP6788573B6
(ja)
|
2014-04-10 |
2020-12-16 |
シアトル チルドレンズ ホスピタル, ディービーエー シアトル チルドレンズ リサーチ インスティテュート |
メトトレキサートによる選択と組み合わせたSleeping Beautyトランスポゾンによる遺伝子改変T細胞の製造
|
|
CN106459917B
(zh)
|
2014-04-23 |
2021-03-09 |
朱诺治疗学股份有限公司 |
分离、培养和遗传工程改造用于过继治疗的免疫细胞群的方法
|
|
EP3805371A1
(en)
|
2014-05-15 |
2021-04-14 |
National University of Singapore |
Modified natural killer cells and uses thereof
|
|
EP3673915A1
(en)
*
|
2014-06-30 |
2020-07-01 |
Altor BioScience Corporation |
Il-15-based molecules and methods of use thereof
|
|
US9744483B2
(en)
|
2014-07-02 |
2017-08-29 |
Flodesign Sonics, Inc. |
Large scale acoustic separation device
|
|
GB201506423D0
(en)
|
2015-04-15 |
2015-05-27 |
Tc Biopharm Ltd |
Gamma delta T cells and uses thereof
|
|
JP7054622B2
(ja)
|
2014-07-21 |
2022-04-14 |
ノバルティス アーゲー |
ヒト化抗bcmaキメラ抗原受容体を使用した癌の処置
|
|
WO2016014535A1
(en)
|
2014-07-21 |
2016-01-28 |
Novartis Ag |
Treatment of cancer using a cll-1 chimeric antigen receptor
|
|
JP6831777B2
(ja)
|
2014-07-21 |
2021-02-17 |
ノバルティス アーゲー |
Cd33キメラ抗原受容体を使用する癌の処置
|
|
JP6625627B2
(ja)
|
2014-10-14 |
2019-12-25 |
ハロザイム インコーポレイテッド |
アデノシンデアミナーゼ−2(ada2)、その変異体の組成物およびそれを使用する方法
|
|
EP3215534B1
(en)
|
2014-11-05 |
2020-04-15 |
Board of Regents, The University of Texas System |
Chimeric antigen receptors (car) to selectively target protein complexes
|
|
WO2016109668A1
(en)
*
|
2014-12-31 |
2016-07-07 |
Anthrogenesis Corporation |
Methods of treating hematological disorders, solid tumors, or infectious diseases using natural killer cells
|
|
WO2016115445A1
(en)
*
|
2015-01-16 |
2016-07-21 |
The Johns Hopkins University |
Synthetic enhancement of the t-cell armamentarium as an anti-cancer therapy
|
|
US10377988B2
(en)
|
2015-01-23 |
2019-08-13 |
Musc Foundation For Research Development |
Cytokine receptor genes and the use thereof to enhance therapy
|
|
HK1245287A1
(zh)
|
2015-01-26 |
2018-08-24 |
The University Of Chicago |
IL13RAα2结合剂和其在癌症治疗中的用途
|
|
EP3250611B1
(en)
|
2015-01-26 |
2021-04-21 |
The University of Chicago |
Car t-cells recognizing cancer-specific il 13r-alpha2
|
|
EP3256496B1
(en)
*
|
2015-02-12 |
2020-12-30 |
University Health Network |
Chimeric antigen receptors
|
|
JP6947647B2
(ja)
|
2015-02-24 |
2021-10-13 |
ボード オブ リージェンツ, ザ ユニバーシティ オブ テキサス システムBoard Of Regents, The University Of Texas System |
遺伝子改変t細胞の選択方法
|
|
EP3268470B1
(en)
*
|
2015-03-11 |
2020-11-18 |
Board of Regents, The University of Texas System |
Transposase polypeptides and uses thereof
|
|
CN108473957B
(zh)
|
2015-04-17 |
2024-07-16 |
诺华股份有限公司 |
改善嵌合抗原受体表达细胞的功效和扩增的方法
|
|
US11708572B2
(en)
|
2015-04-29 |
2023-07-25 |
Flodesign Sonics, Inc. |
Acoustic cell separation techniques and processes
|
|
US11377651B2
(en)
|
2016-10-19 |
2022-07-05 |
Flodesign Sonics, Inc. |
Cell therapy processes utilizing acoustophoresis
|
|
US11021699B2
(en)
|
2015-04-29 |
2021-06-01 |
FioDesign Sonics, Inc. |
Separation using angled acoustic waves
|
|
GB201507368D0
(en)
|
2015-04-30 |
2015-06-17 |
Ucl Business Plc |
Cell
|
|
CA2989347A1
(en)
*
|
2015-06-12 |
2016-12-15 |
Lentigen Technology, Inc. |
Method to treat cancer with engineered t-cells
|
|
TW202444897A
(zh)
*
|
2015-06-25 |
2024-11-16 |
美商生物細胞基因治療有限公司 |
嵌合抗原受體(car)、組合物及其使用方法
|
|
AR105433A1
(es)
|
2015-07-21 |
2017-10-04 |
Novartis Ag |
Métodos para mejorar la eficacia y expansión de las células inmunes
|
|
US11474085B2
(en)
|
2015-07-28 |
2022-10-18 |
Flodesign Sonics, Inc. |
Expanded bed affinity selection
|
|
US11459540B2
(en)
|
2015-07-28 |
2022-10-04 |
Flodesign Sonics, Inc. |
Expanded bed affinity selection
|
|
CA2994412A1
(en)
|
2015-07-31 |
2017-02-09 |
Memorial Sloan-Kettering Cancer Center |
Antigen-binding proteins targeting cd56 and uses thereof
|
|
US10976232B2
(en)
|
2015-08-24 |
2021-04-13 |
Gpb Scientific, Inc. |
Methods and devices for multi-step cell purification and concentration
|
|
MA44909A
(fr)
|
2015-09-15 |
2018-07-25 |
Acerta Pharma Bv |
Association thérapeutique d'un inhibiteur du cd19 et d'un inhibiteur de la btk
|
|
AU2016323153B2
(en)
|
2015-09-15 |
2021-04-22 |
Board Of Regents, The University Of Texas System |
T-cell receptor (TCR)-binding antibodies and uses thereof
|
|
WO2017075147A1
(en)
|
2015-10-27 |
2017-05-04 |
Board Of Regents, The University Of Texas System |
Chimeric antigen receptor molecules and uses thereof
|
|
TW202344686A
(zh)
|
2015-10-30 |
2023-11-16 |
美國加利福尼亞大學董事會 |
從幹細胞產生t細胞之方法及使用該t細胞之免疫療法
|
|
US10691773B2
(en)
|
2015-12-30 |
2020-06-23 |
General Electric Company |
Cell processing techniques
|
|
WO2017123548A1
(en)
*
|
2016-01-14 |
2017-07-20 |
Seattle Children's Hospital (dba Seattle Children's Research Institute) |
Tumor-specific ifna secretion by car t-cells to reprogram the solid tumor microenvironment
|
|
US20200063157A9
(en)
*
|
2016-02-26 |
2020-02-27 |
Poseida Therapeutics, Inc. |
Transposon system and methods of use
|
|
WO2019055946A1
(en)
*
|
2017-09-18 |
2019-03-21 |
F1 Oncology, Inc. |
METHODS AND COMPOSITIONS FOR THE GENETIC MODIFICATION AND EXPANSION OF LYMPHOCYTES AND THE REGULATION OF THE ACTIVITY THEREOF
|
|
US11111505B2
(en)
|
2016-03-19 |
2021-09-07 |
Exuma Biotech, Corp. |
Methods and compositions for transducing lymphocytes and regulating the activity thereof
|
|
EP3430136A2
(en)
*
|
2016-03-19 |
2019-01-23 |
F1 Oncology, Inc. |
Methods and compositions for transducing lymphocytes and regulated expansion thereof
|
|
US11325948B2
(en)
|
2016-03-19 |
2022-05-10 |
Exuma Biotech Corp. |
Methods and compositions for genetically modifying lymphocytes to express polypeptides comprising the intracellular domain of MPL
|
|
CA3177398A1
(en)
|
2016-04-01 |
2017-10-05 |
Kite Pharma, Inc. |
Chimeric receptors and methods of use thereof
|
|
AR108067A1
(es)
|
2016-04-01 |
2018-07-11 |
Kite Pharma Inc |
Moléculas de unión y métodos de uso de los mismos
|
|
CN109328074A
(zh)
|
2016-04-01 |
2019-02-12 |
凯德药业股份有限公司 |
嵌合抗原和t细胞受体及使用的方法
|
|
CA3019835A1
(en)
|
2016-04-08 |
2017-10-12 |
Purdue Research Foundation |
Methods and compositions for car t cell therapy
|
|
WO2017180587A2
(en)
|
2016-04-11 |
2017-10-19 |
Obsidian Therapeutics, Inc. |
Regulated biocircuit systems
|
|
US10188749B2
(en)
|
2016-04-14 |
2019-01-29 |
Fred Hutchinson Cancer Research Center |
Compositions and methods to program therapeutic cells using targeted nucleic acid nanocarriers
|
|
ES2933961T3
(es)
|
2016-04-15 |
2023-02-15 |
Memorial Sloan Kettering Cancer Center |
Células T transgénicas y composiciones de células T de receptor de antígeno quimérico y métodos relacionados
|
|
US11085035B2
(en)
|
2016-05-03 |
2021-08-10 |
Flodesign Sonics, Inc. |
Therapeutic cell washing, concentration, and separation utilizing acoustophoresis
|
|
US11214789B2
(en)
|
2016-05-03 |
2022-01-04 |
Flodesign Sonics, Inc. |
Concentration and washing of particles with acoustics
|
|
CN105968210B
(zh)
*
|
2016-05-13 |
2019-05-31 |
深圳生创精准医疗科技有限公司 |
靶向cd22的强杀伤性嵌合抗原受体t细胞及其在制备治疗肿瘤的药物中的用途
|
|
EP3463401A4
(en)
*
|
2016-06-03 |
2020-01-22 |
Memorial Sloan Kettering Cancer Center |
ADOPTIVE CELL THERAPIES AS EARLY TREATMENT OPTIONS
|
|
AU2017279548B2
(en)
|
2016-06-08 |
2024-08-08 |
Precigen, Inc. |
CD33 specific chimeric antigen receptors
|
|
US11472856B2
(en)
|
2016-06-13 |
2022-10-18 |
Torque Therapeutics, Inc. |
Methods and compositions for promoting immune cell function
|
|
CA3029197A1
(en)
*
|
2016-06-24 |
2017-12-28 |
Icell Gene Therapeutics Llc |
Chimeric antigen receptors (cars), compositions and methods thereof
|
|
AU2017299854A1
(en)
*
|
2016-07-18 |
2019-01-31 |
Helix Biopharma Corp. |
CAR immune cells directed to carcinoembryonic antigen related cell adhesion molecule 6 to treat cancer
|
|
CN109804246B
(zh)
*
|
2016-08-01 |
2022-05-17 |
健康研究公司 |
用于快速克隆t细胞受体的组合物和方法
|
|
CN106222201B
(zh)
*
|
2016-08-27 |
2017-11-28 |
北京艺妙神州医疗科技有限公司 |
一种制备car‑t细胞的方法以及制得的car‑t细胞及其应用
|
|
US20190119636A1
(en)
|
2017-10-23 |
2019-04-25 |
Poseida Therapeutics, Inc. |
Modified stem cell memory t cells, methods of making and methods of using same
|
|
KR102588469B1
(ko)
*
|
2016-09-30 |
2023-10-11 |
포세이다 테라퓨틱스, 인크. |
변형된 줄기세포 기억 t 세포, 이의 제조 방법 및 사용 방법
|
|
CN110381963A
(zh)
|
2016-10-13 |
2019-10-25 |
朱诺治疗学股份有限公司 |
涉及色氨酸代谢途径调节剂的免疫治疗方法和组合物
|
|
JP2020513248A
(ja)
|
2016-10-19 |
2020-05-14 |
フロデザイン ソニックス, インク.Flodesign Sonics, Inc. |
音響による親和性細胞抽出
|
|
US20190290728A1
(en)
*
|
2016-10-21 |
2019-09-26 |
Children's Medical Center Corporation |
Methods related to breaking t cell exhaustion
|
|
BR112019011277A2
(pt)
|
2016-12-02 |
2019-10-22 |
University Of Southern California |
polinucleotídeo, sistema de expressão recombinante, vetor, polipeptídeo, célula recombinante, polipeptídeo de receptor imune sintético isolado ou heterodímero de polipeptídeo, célula efetora imune ou célula-tronco, população de células imunes ou efetoras, métodos de fabricação de uma célula efetora imune que expressa sir, de geração de uma população de células modificadas por rna, de fornecimento de imunidade antidoença e de tratamento ou prevenção de uma doença, composição, uso ou método, kit, e, sequência de aminoácidos.
|
|
US20200095547A1
(en)
*
|
2016-12-02 |
2020-03-26 |
Darya ALIZADEH |
Methods for manufacturing t cells expressing of chimeric antigen receptors and other receptors
|
|
JP7275043B2
(ja)
|
2016-12-16 |
2023-05-17 |
ビー-モーゲン・バイオテクノロジーズ,インコーポレーテッド |
増大したhATファミリートランスポゾン媒介遺伝子導入ならびに関連する組成物、システムおよび方法
|
|
US11278570B2
(en)
|
2016-12-16 |
2022-03-22 |
B-Mogen Biotechnologies, Inc. |
Enhanced hAT family transposon-mediated gene transfer and associated compositions, systems, and methods
|
|
GB201621889D0
(en)
*
|
2016-12-21 |
2017-02-01 |
Autolus Ltd |
Cell
|
|
EP3567049A4
(en)
|
2016-12-28 |
2020-08-26 |
Green Cross Lab Cell Corporation |
CHEMERICAL ANTIGENIC RECEPTOR AND NATURAL KILLER CELLS EXPRESSING THE SAME
|
|
CN108250301A
(zh)
*
|
2016-12-29 |
2018-07-06 |
天津天锐生物科技有限公司 |
一种多靶点嵌合抗原受体
|
|
EP3565535A4
(en)
|
2017-01-05 |
2020-12-30 |
Fred Hutchinson Cancer Research Center |
SYSTEMS AND METHODS FOR IMPROVING THE EFFECTIVENESS OF A VACCINE
|
|
US11466088B2
(en)
*
|
2017-01-05 |
2022-10-11 |
Helix Biopharma Corp. |
VEGFR-2 car immune cells to treat cancers
|
|
SG11201906213UA
(en)
|
2017-01-10 |
2019-08-27 |
Intrexon Corp |
Modulating expression of polypeptides via new gene switch expression systems
|
|
MX2019008503A
(es)
|
2017-01-18 |
2019-09-13 |
F1 Oncology Inc |
Receptores de antigenos quimericos contra axl o ror2 y metodos de uso de los mismos.
|
|
US11649288B2
(en)
|
2017-02-07 |
2023-05-16 |
Seattle Children's Hospital |
Phospholipid ether (PLE) CAR T cell tumor targeting (CTCT) agents
|
|
US11850262B2
(en)
|
2017-02-28 |
2023-12-26 |
Purdue Research Foundation |
Compositions and methods for CAR T cell therapy
|
|
SG11201907814SA
(en)
*
|
2017-03-03 |
2019-09-27 |
F1 Oncology Inc |
Methods and compositions for transducing and expanding lymphocytes and regulating the activity thereof
|
|
US11629340B2
(en)
|
2017-03-03 |
2023-04-18 |
Obsidian Therapeutics, Inc. |
DHFR tunable protein regulation
|
|
KR102746901B1
(ko)
*
|
2017-03-03 |
2024-12-26 |
옵시디안 테라퓨틱스, 인크. |
Cd19 조성물 및 면역요법을 위한 방법
|
|
WO2018169922A2
(en)
|
2017-03-13 |
2018-09-20 |
Kite Pharma, Inc. |
Chimeric antigen receptors for melanoma and uses thereof
|
|
IL269553B2
(en)
|
2017-03-27 |
2025-10-01 |
Nat Univ Singapore |
Truncated NKG2D chimeric receptors and their uses in immunotherapy with natural killer cells
|
|
MX2019011570A
(es)
|
2017-03-27 |
2019-11-18 |
Nat Univ Singapore |
Lineas celulares estimuladoras para expansion y activacion ex vivo de celulas asesinas naturales.
|
|
EP3600323A4
(en)
|
2017-03-31 |
2020-11-11 |
The Board of Trustees of the Leland Stanford Junior University |
METHODS OF TREATING T-LYMPHOCYTE DEPLETION BY INHIBITIONING OR MODULATING T-LYMPHOCYTE RECEPTOR SIGNALING
|
|
CN110770345A
(zh)
*
|
2017-04-14 |
2020-02-07 |
托尔奈公司 |
免疫调节多核苷酸、抗体缀合物及其使用方法
|
|
AU2018254442B2
(en)
*
|
2017-04-18 |
2024-03-28 |
FUJIFILM Cellular Dynamics, Inc. |
Antigen-specific immune effector cells
|
|
CN110753555A
(zh)
*
|
2017-04-19 |
2020-02-04 |
得克萨斯州大学系统董事会 |
表达工程化抗原受体的免疫细胞
|
|
JOP20180042A1
(ar)
|
2017-04-24 |
2019-01-30 |
Kite Pharma Inc |
نطاقات ربط مولد ضد متوافقة مع البشر وطرق الاستخدام
|
|
US12384830B2
(en)
|
2017-06-02 |
2025-08-12 |
Regents Of The University Of Minnesota |
Compositions and methods for improving immunotherapy
|
|
CA3067226A1
(en)
*
|
2017-06-16 |
2018-12-20 |
Mayo Foundation For Medical Education And Research |
Materials and methods for increasing immune responses
|
|
WO2018237022A1
(en)
|
2017-06-21 |
2018-12-27 |
Icell Gene Therapeutics Llc |
Chimeric antigen receptors (cars), compositions and methods thereof
|
|
CA3068286A1
(en)
*
|
2017-06-22 |
2018-12-27 |
Board Of Regents, The University Of Texas System |
Methods for producing regulatory immune cells and uses thereof
|
|
KR20200032174A
(ko)
*
|
2017-07-25 |
2020-03-25 |
보드 오브 리전츠, 더 유니버시티 오브 텍사스 시스템 |
강화된 키메라 항원 수용체 및 이의 용도
|
|
CN109337872B
(zh)
*
|
2017-07-27 |
2023-06-23 |
上海细胞治疗研究院 |
高效扩增car-t细胞的人工抗原递呈细胞及其用途
|
|
ES2992909T3
(en)
*
|
2017-08-09 |
2024-12-19 |
Juno Therapeutics Inc |
Methods and compositions for preparing genetically engineered cells
|
|
CA3074495A1
(en)
|
2017-09-01 |
2019-03-07 |
Gpb Scientific, Llc |
Methods for preparing therapeutically active cells using microfluidics
|
|
US11447745B2
(en)
|
2017-09-01 |
2022-09-20 |
Lonza Walkersville, Inc. |
End-to-end cell therapy automation
|
|
KR20210032924A
(ko)
|
2017-09-05 |
2021-03-25 |
토크 테라퓨틱스, 인코포레이티드 |
치료용 단백질 조성물 및 그의 제조 및 사용 방법
|
|
AU2018347601B2
(en)
*
|
2017-10-12 |
2025-09-04 |
Icell Gene Therapeutics, Llc |
Compound chimeric antigen receptor (cCAR) targeting multiple antigens, compositions and methods of use thereof
|
|
JP2021500882A
(ja)
|
2017-10-18 |
2021-01-14 |
プレシゲン,インコーポレイテッド |
スペーサーを含むポリペプチド組成物
|
|
CA3079999A1
(en)
*
|
2017-11-07 |
2019-05-16 |
The Board Of Regents Of The University Of Texas System |
Targeting lilrb4 with car-t or car-nk cells in the treatment of cancer
|
|
EP3710020A4
(en)
*
|
2017-11-14 |
2021-06-23 |
Memorial Sloan-Kettering Cancer Center |
IL-36 SECRECTING IMMUNOREACTIVE CELLS AND RELATED USES
|
|
US12116417B2
(en)
|
2017-11-14 |
2024-10-15 |
GC Cell Corporation |
Anti-HER2 antibody or antigen-binding fragment thereof, and chimeric antigen receptor comprising same
|
|
US11649294B2
(en)
|
2017-11-14 |
2023-05-16 |
GC Cell Corporation |
Anti-HER2 antibody or antigen-binding fragment thereof, and chimeric antigen receptor comprising same
|
|
EP3710034A4
(en)
*
|
2017-11-14 |
2022-01-26 |
Arcellx, Inc. |
MULTIFUNCTIONAL IMMUNOCELLULAR THERAPIES
|
|
WO2019099707A1
(en)
|
2017-11-16 |
2019-05-23 |
Kite Pharma, Inc |
Modified chimeric antigen receptors and methods of use
|
|
CN107974460B
(zh)
*
|
2017-11-30 |
2021-06-01 |
山东兴瑞生物科技有限公司 |
针对hiv-1的嵌合抗原受体基因、具有该基因的质粒、t细胞、试剂盒及应用
|
|
BR112020009889A2
(pt)
|
2017-12-14 |
2020-11-03 |
Flodesign Sonics, Inc. |
acionador e controlador de transdutor acústico
|
|
CN108251376B
(zh)
*
|
2017-12-21 |
2021-08-13 |
王文举 |
人工抗原递呈细胞及其构建方法与在嵌合抗原受体t细胞扩增中的应用
|
|
CU24545B1
(es)
*
|
2017-12-29 |
2021-09-07 |
Ct Ingenieria Genetica Biotecnologia |
Péptido antagonista de la actividad de la interleucina-15
|
|
US12491153B2
(en)
|
2018-01-03 |
2025-12-09 |
Qu Biologics Inc. |
Innate targeting of adoptive cellular therapies
|
|
EP3735255A4
(en)
*
|
2018-01-05 |
2021-09-22 |
Maxcyte, Inc. |
CHRONIC CANCER TREATMENT BY CARS
|
|
CN120154716A
(zh)
|
2018-01-22 |
2025-06-17 |
恩多塞特公司 |
Car t细胞的使用方法
|
|
WO2019147604A2
(en)
*
|
2018-01-23 |
2019-08-01 |
Vanderbilt University |
Self-antigen specific t-cells as vacines for augmenting engraftment and stability of autologous transfer
|
|
CN110093351B
(zh)
*
|
2018-01-29 |
2023-06-23 |
华南生物医药研究院 |
可分离的核酸、多肽、重组载体、重组细胞及应用
|
|
JP7774961B2
(ja)
|
2018-02-06 |
2025-11-25 |
シアトル チルドレンズ ホスピタル ディー/ビー/エイ シアトル チルドレンズ リサーチ インスティテュート |
フルオレセイン結合エーテルリン脂質(fl-ple)で標識された腫瘍に対して最適なt細胞機能を示すフルオレセイン特異的car
|
|
US12258381B2
(en)
|
2018-02-09 |
2025-03-25 |
National University Of Singapore |
Activating chimeric receptors and uses thereof in natural killer cell immunotherapy
|
|
MX2020008327A
(es)
|
2018-02-09 |
2020-10-28 |
Immatics Us Inc |
Metodos para preparar celulas t.
|
|
EP3752203A1
(en)
*
|
2018-02-13 |
2020-12-23 |
Novartis AG |
Chimeric antigen receptor therapy in combination with il-15r and il15
|
|
SG11202007513PA
(en)
|
2018-02-16 |
2020-09-29 |
Kite Pharma Inc |
Modified pluripotent stem cells and methods of making and use
|
|
EP3755349A4
(en)
|
2018-02-21 |
2021-11-17 |
Board of Regents, The University of Texas System |
PROCESS FOR ACTIVATION AND EXPANSION OF NATURAL KILLER CELLS AND THEIR USES
|
|
CA3091674A1
(en)
|
2018-02-23 |
2019-08-29 |
Endocyte, Inc. |
Sequencing method for car t cell therapy
|
|
JP7438123B2
(ja)
*
|
2018-03-14 |
2024-02-26 |
シアトル チルドレンズ ホスピタル (ディービーエイ シアトル チルドレンズ リサーチ インスティテュート) |
腫瘍特異的T細胞免疫療法用のIL-13受容体α2(IL13Rα2)標的キメラ抗原受容体
|
|
CA3093791A1
(en)
*
|
2018-03-14 |
2019-09-19 |
Seattle Children's Hospital (dba Seattle Children's Research Institute) |
Il-13 receptor alpha 2 targeted, zetakine directed t cell immunotherapy
|
|
CN112055717B
(zh)
|
2018-04-02 |
2024-04-26 |
新加坡国立大学 |
用在免疫细胞中表达的膜结合抗细胞因子非信号传导粘合剂中和人细胞因子
|
|
WO2019195586A1
(en)
|
2018-04-06 |
2019-10-10 |
The Regents Of The University Of California |
Methods of treating egfrviii expressing glioblastomas
|
|
AU2019249221A1
(en)
|
2018-04-06 |
2020-10-22 |
The Regents Of The University Of California |
Methods of treating glioblastomas
|
|
US10869888B2
(en)
|
2018-04-17 |
2020-12-22 |
Innovative Cellular Therapeutics CO., LTD. |
Modified cell expansion and uses thereof
|
|
CN112055695A
(zh)
*
|
2018-05-01 |
2020-12-08 |
弗莱德哈钦森癌症研究中心 |
用于基因表达的纳米粒子和其用途
|
|
UY38247A
(es)
|
2018-05-30 |
2019-12-31 |
Novartis Ag |
Anticuerpos frente a entpd2, terapias de combinación y métodos de uso de los anticuerpos y las terapias de combinación
|
|
JP2021525534A
(ja)
*
|
2018-06-04 |
2021-09-27 |
プレシゲン,インコーポレイテッド |
Muc16特異的キメラ抗原受容体およびそれらの使用
|
|
WO2019241315A1
(en)
|
2018-06-12 |
2019-12-19 |
Obsidian Therapeutics, Inc. |
Pde5 derived regulatory constructs and methods of use in immunotherapy
|
|
WO2019241241A1
(en)
*
|
2018-06-12 |
2019-12-19 |
Apdn (B.V.I), Inc. |
Engineered lymphocyte compositions, methods and systems
|
|
CN112203725A
(zh)
|
2018-06-13 |
2021-01-08 |
诺华股份有限公司 |
Bcma嵌合抗原受体及其用途
|
|
WO2019246486A2
(en)
|
2018-06-21 |
2019-12-26 |
B-Mogen Biotechnologies, Inc. |
ENHANCED hAT FAMILY TRANSPOSON-MEDIATED GENE TRANSFER AND ASSOCIATED COMPOSITIONS, SYSTEMS, AND METHODS
|
|
CN120775065A
(zh)
|
2018-07-09 |
2025-10-14 |
普瑞赛格恩公司 |
融合构建体及其使用方法
|
|
AU2019301147A1
(en)
|
2018-07-10 |
2021-01-21 |
Precigen, Inc. |
ROR-1 specific chimeric antigen receptors and uses thereof
|
|
WO2020014528A1
(en)
*
|
2018-07-13 |
2020-01-16 |
The Regents Of The University Of California |
Retrotransposon-based delivery vehicle and methods of use thereof
|
|
CN108949695A
(zh)
*
|
2018-08-14 |
2018-12-07 |
杭州荣泽生物科技有限公司 |
一种非病毒载体共表达il18的car-t细胞构建及其应用
|
|
WO2020037142A1
(en)
|
2018-08-17 |
2020-02-20 |
Yale University |
Compositions and methods for high-throughput activation screening to boost t cell effector function
|
|
CN110862967A
(zh)
*
|
2018-08-27 |
2020-03-06 |
天津天锐生物科技有限公司 |
一种不依赖细胞因子培养的自然杀伤细胞系silk-nk
|
|
EP3844186A4
(en)
|
2018-08-29 |
2022-08-17 |
National University of Singapore |
METHOD OF SPECIFIC STIMULATION OF SURVIVAL AND EXPANSION OF GENETICALLY MODIFIED IMMUNE CELLS
|
|
US12240915B2
(en)
|
2018-08-30 |
2025-03-04 |
Innovative Cellular Therapeutics Holdings, Ltd. |
Chimeric antigen receptor cells for treating solid tumor
|
|
KR20210053925A
(ko)
|
2018-08-31 |
2021-05-12 |
노일 이뮨 바이오테크 가부시키가이샤 |
Car 발현 t 세포 및 car 발현 벡터
|
|
AU2019335014A1
(en)
*
|
2018-09-05 |
2021-03-25 |
Poseida Therapeutics, Inc. |
Allogeneic cell compositions and methods of use
|
|
CN109320615B
(zh)
*
|
2018-09-25 |
2023-09-22 |
上海恒润达生生物科技股份有限公司 |
靶向新型bcma的嵌合抗原受体及其用途
|
|
CN112752847B
(zh)
|
2018-09-28 |
2025-03-28 |
奥克泰生物科技股份有限公司 |
磁性分离
|
|
US12331320B2
(en)
|
2018-10-10 |
2025-06-17 |
The Research Foundation For The State University Of New York |
Genome edited cancer cell vaccines
|
|
US11701408B2
(en)
*
|
2018-10-11 |
2023-07-18 |
Nantcell, Inc. |
Treatment of immunosuppressed subjects
|
|
US20210386788A1
(en)
|
2018-10-24 |
2021-12-16 |
Obsidian Therapeutics, Inc. |
Er tunable protein regulation
|
|
WO2020092696A1
(en)
*
|
2018-10-31 |
2020-05-07 |
Musc Foundation For Research Development |
Ex vivo activation and expansion of t cells for adoptive cell transfer therapy
|
|
CN116286665A
(zh)
*
|
2018-11-16 |
2023-06-23 |
上海煦顼技术有限公司 |
嵌合抗原受体细胞分泌治疗剂
|
|
US10918667B2
(en)
|
2018-11-20 |
2021-02-16 |
Innovative Cellular Therapeutics CO., LTD. |
Modified cell expressing therapeutic agent and uses thereof
|
|
WO2020106843A1
(en)
*
|
2018-11-20 |
2020-05-28 |
Innovative Cellular Therapeutics Holdings, Ltd. |
Modified cell expressing therapeutic agent and uses thereof
|
|
CN113395972A
(zh)
*
|
2018-11-30 |
2021-09-14 |
细胞结构公司 |
胎盘源性同种异体car-t细胞及其用途
|
|
CN120025452A
(zh)
|
2018-12-12 |
2025-05-23 |
凯德药业股份有限公司 |
嵌合抗原和t细胞受体及使用的方法
|
|
SG11202106384YA
(en)
|
2018-12-21 |
2021-07-29 |
Octane Biotech Inc |
Carousel for modular biologic production units
|
|
KR20210108406A
(ko)
|
2018-12-21 |
2021-09-02 |
론자 워커스빌 아이엔씨. |
바이러스 벡터의 자동화된 생산
|
|
US12404347B2
(en)
|
2019-02-07 |
2025-09-02 |
Board Of Regents, The University Of Texas System |
Glucuronoxylomannan (GXM) receptor chimeric antigen receptors and use thereof
|
|
US12297259B2
(en)
|
2019-02-07 |
2025-05-13 |
Board Of Regents, The University Of Texas System |
Aspergillus antigen chimeric receptors and use thereof
|
|
KR20210125510A
(ko)
|
2019-02-08 |
2021-10-18 |
론자 워커스빌 아이엔씨. |
자동화 생물반응기에서 사용하기 위한 세포 농축 방법 및 장치
|
|
KR20210137085A
(ko)
*
|
2019-03-05 |
2021-11-17 |
엔카르타, 인크. |
Cd19 유도된 키메라 항원 수용체 및 면역 요법에서 이의 용도
|
|
CA3134500A1
(en)
*
|
2019-03-22 |
2020-10-01 |
Spotlight Therapeutics |
Targeted active gene editing agent and methods of use
|
|
EP3964568A4
(en)
*
|
2019-04-04 |
2023-01-11 |
Shanghai Pharmaceuticals Holding Co., Ltd. |
IMMUNE CELL CONTAINING A TUMOR ANTIGEN RECOGNITION RECEPTOR AND THEIR APPLICATION
|
|
EP3999081A1
(en)
|
2019-07-18 |
2022-05-25 |
GPB Scientific, Inc. |
Ordered processing of blood products to produce therapeutically active cells
|
|
US20220268762A1
(en)
*
|
2019-07-28 |
2022-08-25 |
H. Lee Moffitt Cancer Center And Research Institute, Inc. |
Methods, systems, and computer-readable media for predicting a cancer patient's response to immune-based or targeted therapy
|
|
WO2021019706A1
(ja)
*
|
2019-07-31 |
2021-02-04 |
国立大学法人信州大学 |
Car発現免疫細胞を含む細胞集団の製造方法
|
|
US12116578B2
(en)
|
2019-08-07 |
2024-10-15 |
APDN (B.V.1.) 1nc. |
Methods and systems of PCR-based recombinant adeno-associated virus manufacture
|
|
US20230092895A1
(en)
|
2019-08-30 |
2023-03-23 |
Obsidian Therapeutics, Inc. |
Tandem cd19 car-based compositions and methods for immunotherapy
|
|
WO2021046451A1
(en)
|
2019-09-06 |
2021-03-11 |
Obsidian Therapeutics, Inc. |
Compositions and methods for dhfr tunable protein regulation
|
|
EP4028413A1
(en)
|
2019-09-10 |
2022-07-20 |
Obsidian Therapeutics, Inc. |
Ca2-il15 fusion proteins for tunable regulation
|
|
EP4031578A1
(en)
|
2019-09-18 |
2022-07-27 |
Novartis AG |
Entpd2 antibodies, combination therapies, and methods of using the antibodies and combination therapies
|
|
US20230210984A1
(en)
*
|
2019-10-23 |
2023-07-06 |
The Council Of The Queensland Institute Of Medical Research |
Adoptive immunotherapy
|
|
CN114729292A
(zh)
|
2019-10-24 |
2022-07-08 |
奥克泰生物科技股份有限公司 |
具有经改进的细胞接触表面的细胞培养室
|
|
WO2021096850A1
(en)
|
2019-11-11 |
2021-05-20 |
Lonza Walkersville, Inc. |
Quality control methods for automated cell processing
|
|
PH12022551290A1
(en)
|
2019-11-26 |
2023-11-29 |
Novartis Ag |
Cd19 and cd22 chimeric antigen receptors and uses thereof
|
|
CN115315434A
(zh)
*
|
2019-12-05 |
2022-11-08 |
免疫靶向有限公司 |
白细胞介素15融合蛋白和前药及其组合物和方法
|
|
TW202136317A
(zh)
*
|
2019-12-20 |
2021-10-01 |
美商再生元醫藥公司 |
新穎之il2促效劑及其使用方法(二)
|
|
JP2023508465A
(ja)
|
2019-12-28 |
2023-03-02 |
ジーピービー・サイエンティフィック・インコーポレイテッド |
粒子および細胞を処理するためのマイクロ流体カートリッジ
|
|
WO2021163191A1
(en)
|
2020-02-10 |
2021-08-19 |
Board Of Regents, The University Of Texas System |
Methods for rapid cloning and expression of hla class i cells
|
|
US12076343B2
(en)
|
2020-02-19 |
2024-09-03 |
Innovative Cellular Therapeutics Holdings, Ltd. |
Engineered safety in cell therapy
|
|
US20220169694A1
(en)
*
|
2020-02-20 |
2022-06-02 |
Kite Pharma, Inc. |
Chimeric antigen receptor t cell therapy
|
|
EP4121071A4
(en)
*
|
2020-03-19 |
2024-07-24 |
Vascular Biosciences |
PEPTIDE CAR FOR IMPROVED CORONAVIRUS SURVIVAL
|
|
WO2021191870A1
(en)
*
|
2020-03-27 |
2021-09-30 |
Dcprime B.V. |
Ex vivo use of modified cells of leukemic origin for enhancing the efficacy of adoptive cell therapy
|
|
AU2021249123A1
(en)
*
|
2020-03-31 |
2022-10-27 |
Walking Fish Therapeutics |
Modified B cells and methods of use thereof
|
|
EP4127188A4
(en)
|
2020-03-31 |
2024-08-21 |
Walking Fish Therapeutics |
MODIFIED B CELLS AND METHODS OF USE THEREOF
|
|
US12043654B2
(en)
|
2020-06-02 |
2024-07-23 |
Innovative Cellular Therapeutics Holdings, Ltd. |
Anti-GCC antibody and CAR thereof for treating digestive system cancer
|
|
EP4171617A1
(en)
|
2020-06-30 |
2023-05-03 |
Mendus B.V. |
Use of leukemia-derived cells in ovarian cancer vaccines
|
|
WO2022011256A1
(en)
|
2020-07-10 |
2022-01-13 |
Precigen, Inc. |
Fusion constructs and methods of using thereof
|
|
US20240059787A1
(en)
*
|
2020-09-17 |
2024-02-22 |
SunnyBay Bio Tech, Inc. |
HERV-K Antibody Therapeutics
|
|
AU2021377699A1
(en)
|
2020-11-13 |
2023-06-15 |
Catamaran Bio, Inc. |
Genetically modified natural killer cells and methods of use thereof
|
|
US20220162288A1
(en)
|
2020-11-25 |
2022-05-26 |
Catamaran Bio, Inc. |
Cellular therapeutics engineered with signal modulators and methods of use thereof
|
|
US11459372B2
(en)
|
2020-11-30 |
2022-10-04 |
Crispr Therapeutics Ag |
Gene-edited natural killer cells
|
|
KR20230118887A
(ko)
|
2020-12-03 |
2023-08-14 |
센츄리 쎄라퓨틱스 인코포레이티드 |
유전자 조작 세포 및 이의 용도
|
|
US11661459B2
(en)
|
2020-12-03 |
2023-05-30 |
Century Therapeutics, Inc. |
Artificial cell death polypeptide for chimeric antigen receptor and uses thereof
|
|
CN116635064A
(zh)
|
2020-12-18 |
2023-08-22 |
世纪治疗股份有限公司 |
具有适应性受体特异性的嵌合抗原受体系统
|
|
AU2021410788A1
(en)
*
|
2020-12-23 |
2023-08-03 |
TCR2 Therapeutics Inc. |
Compositions and methods for tcr reprogramming using fusion proteins
|
|
WO2022144632A1
(en)
|
2020-12-30 |
2022-07-07 |
Crispr Therapeutics Ag |
Compositions and methods for differentiating stem cells into nk cells
|
|
US12234473B2
(en)
|
2020-12-31 |
2025-02-25 |
Immatics US, Inc. |
CD8 polypeptides, compositions, and methods of using thereof
|
|
CA3204211A1
(en)
*
|
2021-01-11 |
2022-07-14 |
Helen SABZEVARI |
Chimeric receptor therapy
|
|
MX2023008162A
(es)
*
|
2021-01-19 |
2023-07-24 |
Obsidian Therapeutics Inc |
Composiciones y metodos para la expansion de celulas t y linfocitos infiltrantes del tumor.
|
|
KR20230155521A
(ko)
*
|
2021-03-11 |
2023-11-10 |
카이트 파마 인코포레이티드 |
면역 세포 기능의 향상
|
|
KR20230167416A
(ko)
*
|
2021-04-08 |
2023-12-08 |
주식회사 지씨셀 |
키메라 항원 수용체 및 il-15를 포함하는 융합 단백질
|
|
EP4342983A4
(en)
*
|
2021-05-18 |
2025-07-23 |
Cells & Genes Biotech Shanghai Co Ltd |
CELL MODIFICATION PROCESS
|
|
TW202307210A
(zh)
|
2021-06-01 |
2023-02-16 |
瑞士商諾華公司 |
Cd19和cd22嵌合抗原受體及其用途
|
|
EP4108247A1
(en)
|
2021-06-23 |
2022-12-28 |
Ostravska univerzita |
Urine progenitor cells for use in cancer therapy
|
|
CN117616116A
(zh)
*
|
2021-07-09 |
2024-02-27 |
南京传奇生物科技有限公司 |
突变体il-15组合物及其方法
|
|
CA3231204A1
(en)
*
|
2021-09-18 |
2023-03-23 |
Feng Wang-Johanning |
Herv-k antibody, cell, vaccine, and drug therapeutics
|
|
PE20241173A1
(es)
|
2021-10-14 |
2024-05-28 |
Arsenal Biosciences Inc |
Celulas inmunitarias que tienen arnhc coexpresados y sistemas de compuerta logica
|
|
EP4180049A1
(en)
|
2021-11-16 |
2023-05-17 |
Ostravska univerzita |
Therapeutic composition for cancer treatment
|
|
WO2023150562A1
(en)
*
|
2022-02-01 |
2023-08-10 |
Alaunos Therapeutics, Inc. |
Methods for activation and expansion of t cells
|
|
AU2023221839A1
(en)
*
|
2022-02-15 |
2024-08-22 |
Kite Pharma, Inc. |
Predicting adverse events from immunotherapy.
|
|
US20250228940A1
(en)
*
|
2022-03-11 |
2025-07-17 |
Yale University |
Compositions and methods for efficient and stable genetic modification of eukaryotic cells
|
|
WO2023194911A1
(en)
*
|
2022-04-04 |
2023-10-12 |
Gammadelta Therapeutics Ltd |
Cells expressing an anti-mesothelin car
|
|
KR20240170816A
(ko)
|
2022-04-04 |
2024-12-04 |
감마델타 테라퓨틱스 엘티디 |
신규의 유전자 아모링
|
|
US20250295773A1
(en)
|
2022-05-10 |
2025-09-25 |
Miltenyi Biotec B.V. & Co. KG |
Compositions comprising il-15, il-15 receptor alpha and the intracellular signaling domain of cd2 for immune cell therapy
|
|
KR20250013199A
(ko)
*
|
2022-05-27 |
2025-01-31 |
카이트 파마 인코포레이티드 |
세포 요법 작제물의 비-바이러스 전달
|
|
CN119698467A
(zh)
|
2022-06-08 |
2025-03-25 |
世纪治疗股份有限公司 |
衍生自遗传工程化以具有膜结合的il12的诱导多能干细胞的免疫效应细胞及其用途
|
|
CN115807020A
(zh)
*
|
2022-09-23 |
2023-03-17 |
卡瑞济(北京)生命科技有限公司 |
白介素15受体α装甲CAR-T细胞在降低白介素15诱导的细胞毒性中的用途
|
|
IL320312A
(en)
*
|
2022-10-25 |
2025-06-01 |
Kyverna Therapeutics Inc |
Methods for treating lupus nephritis using anti-cd19 car-t cell therapies
|
|
WO2024102838A1
(en)
|
2022-11-09 |
2024-05-16 |
Century Therapeutics, Inc. |
Engineered interleukin-7 receptors and uses thereof
|
|
JP2025537284A
(ja)
|
2022-11-10 |
2025-11-14 |
センチュリー セラピューティクス,インコーポレイテッド |
抗ネクチン4キメラ抗原受容体を有する遺伝子操作細胞、およびその使用
|
|
CN120265664A
(zh)
*
|
2022-11-25 |
2025-07-04 |
苏州沙砾生物科技有限公司 |
一种融合多肽及其用途
|
|
CN115873803B
(zh)
*
|
2022-11-28 |
2025-06-17 |
上海恩凯细胞技术有限公司 |
提高nk细胞存活和抗肿瘤活性的方法及应用
|
|
WO2024150828A1
(ja)
*
|
2023-01-12 |
2024-07-18 |
積水化学工業株式会社 |
遺伝子導入方法
|
|
WO2024153124A1
(zh)
*
|
2023-01-18 |
2024-07-25 |
南京传奇生物科技有限公司 |
经修饰的原代t细胞及其用途
|
|
WO2025059162A1
(en)
|
2023-09-11 |
2025-03-20 |
Dana-Farber Cancer Institute, Inc. |
Car-engager containing il-2 variants to enhance the functionality of car t cells
|
|
WO2025101938A2
(en)
|
2023-11-10 |
2025-05-15 |
Century Therapeutics, Inc. |
Genetically engineered cells having multi-transmembrane domain chimeric antigen receptors utilizing g protein-coupled receptor scaffolds, and uses thereof
|
|
WO2025106626A1
(en)
|
2023-11-15 |
2025-05-22 |
Century Therapeutics, Inc. |
Genetically engineered cells expressing c-x-c chemokine receptor type 4, and uses thereof
|
|
WO2025226918A1
(en)
*
|
2024-04-24 |
2025-10-30 |
La Jolla Institute For Immunology |
Herv-k envelope protein binders and compositions and methods of use thereof
|
|
CN120365387B
(zh)
*
|
2025-06-25 |
2025-08-29 |
海南大学三亚南繁研究院 |
一种植物免疫诱抗蛋白EqBPIE1及其应用
|