JP2016531108A5 - - Google Patents
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- Publication number
- JP2016531108A5 JP2016531108A5 JP2016528587A JP2016528587A JP2016531108A5 JP 2016531108 A5 JP2016531108 A5 JP 2016531108A5 JP 2016528587 A JP2016528587 A JP 2016528587A JP 2016528587 A JP2016528587 A JP 2016528587A JP 2016531108 A5 JP2016531108 A5 JP 2016531108A5
- Authority
- JP
- Japan
- Prior art keywords
- group
- branched
- linear
- alkyl
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR13/57277 | 2013-07-23 | ||
| FR1357277A FR3008978A1 (fr) | 2013-07-23 | 2013-07-23 | "nouveaux derives d'indole et de pyrrole, leur procede de preparation et les compositions pharmaceutiques qui les contiennent" |
| PCT/FR2014/051884 WO2015011396A1 (fr) | 2013-07-23 | 2014-07-22 | Nouveaux derives d'indole et de pyrrole, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016531108A JP2016531108A (ja) | 2016-10-06 |
| JP2016531108A5 true JP2016531108A5 (https=) | 2017-08-24 |
| JP6458028B2 JP6458028B2 (ja) | 2019-01-23 |
Family
ID=49911607
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016528587A Expired - Fee Related JP6458028B2 (ja) | 2013-07-23 | 2014-07-22 | インドール及びピロールの新規な誘導体、その製造方法及びそれを含む医薬組成物 |
Country Status (31)
| Country | Link |
|---|---|
| US (2) | US9765056B2 (https=) |
| EP (2) | EP3027602B1 (https=) |
| JP (1) | JP6458028B2 (https=) |
| KR (1) | KR102337149B1 (https=) |
| CN (1) | CN105408321B (https=) |
| AR (1) | AR099914A1 (https=) |
| AU (1) | AU2014294866B2 (https=) |
| BR (1) | BR112016001333B1 (https=) |
| CA (1) | CA2917965C (https=) |
| CY (1) | CY1120475T1 (https=) |
| DK (1) | DK3027602T3 (https=) |
| EA (1) | EA028609B1 (https=) |
| ES (1) | ES2687475T3 (https=) |
| FR (1) | FR3008978A1 (https=) |
| HK (1) | HK1218753A1 (https=) |
| HR (1) | HRP20181333T1 (https=) |
| HU (1) | HUE039507T2 (https=) |
| LT (1) | LT3027602T (https=) |
| MX (1) | MX364479B (https=) |
| NZ (1) | NZ715847A (https=) |
| PL (1) | PL3027602T3 (https=) |
| PT (1) | PT3027602T (https=) |
| RS (1) | RS57545B1 (https=) |
| RU (1) | RU2693404C2 (https=) |
| SG (1) | SG11201600004SA (https=) |
| SI (1) | SI3027602T1 (https=) |
| TW (1) | TW201504224A (https=) |
| UA (1) | UA117020C2 (https=) |
| UY (1) | UY35653A (https=) |
| WO (1) | WO2015011396A1 (https=) |
| ZA (1) | ZA201600415B (https=) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105237509A (zh) * | 2015-11-20 | 2016-01-13 | 江苏瑞邦农药厂有限公司 | 一种2,2-二氟-1,3-苯并二恶茂的合成方法 |
| EP3454856B1 (en) | 2016-05-10 | 2024-09-11 | C4 Therapeutics, Inc. | Heterocyclic degronimers for target protein degradation |
| CN109641874A (zh) | 2016-05-10 | 2019-04-16 | C4医药公司 | 用于靶蛋白降解的c3-碳连接的戊二酰亚胺降解决定子体 |
| CN109790143A (zh) | 2016-05-10 | 2019-05-21 | C4医药公司 | 用于靶蛋白降解的胺连接的c3-戊二酰亚胺降解决定子体 |
| ES2990061T3 (es) | 2016-05-10 | 2024-11-28 | C4 Therapeutics Inc | Degronímeros espirocíclicos para la degradación de proteínas diana |
| AU2018208458B2 (en) * | 2017-01-10 | 2020-07-16 | ETH Zürich | Cell-protective compounds and their use |
| TWI743346B (zh) | 2017-03-31 | 2021-10-21 | 國立大學法人東京大學 | 諾羅病毒抗體 |
| CN110769822A (zh) | 2017-06-20 | 2020-02-07 | C4医药公司 | 用于蛋白降解的n/o-连接的降解决定子和降解决定子体 |
| CN108409580A (zh) * | 2018-02-01 | 2018-08-17 | 浙江工业大学 | 一种苄胺类化合物的合成方法 |
| CN120698983A (zh) | 2018-12-20 | 2025-09-26 | C4医药公司 | 靶向蛋白降解 |
| CN116997544A (zh) * | 2021-03-24 | 2023-11-03 | 法国施维雅药厂 | 用于合成5-{5-氯-2-[(3s)-3-[(吗啉-4-基)甲基]-3,4-二氢异喹啉-2(1h)-羰基]苯基}-1,2-二甲基-1h-吡咯-3-甲酸衍生物的新方法及其在生产药物化合物中的应用 |
| US20250387504A1 (en) | 2022-05-20 | 2025-12-25 | Novartis Ag | Antibody-drug conjugates of antineoplastic compounds and methods of use thereof |
| PY24103486A (es) | 2023-11-22 | 2025-06-06 | Servier Lab | Conjugados de anticuerpo anti-cd74-fármaco y métodos de uso de los mismos |
| AR134424A1 (es) | 2023-11-22 | 2026-01-14 | Novartis Ag | Conjugados de anticuerpo anti-cd7-fármaco y métodos de uso de los mismos |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2298832T3 (es) | 2003-10-24 | 2008-05-16 | Glaxo Group Limited | Compuestos heterociclicos. |
| TW200533398A (en) * | 2004-03-29 | 2005-10-16 | Bristol Myers Squibb Co | Novel therapeutic agents for the treatment of migraine |
| AU2005277223C1 (en) * | 2004-08-20 | 2009-05-21 | The Regents Of The University Of Michigan | Small molecule inhibitors of anti-apoptotic Bcl-2 family members and the uses thereof |
| GB0522908D0 (en) | 2005-11-10 | 2005-12-21 | Merck Sharp & Dohme | Therapeutic agents |
| JP2014521595A (ja) * | 2011-05-25 | 2014-08-28 | ブリストル−マイヤーズ スクイブ カンパニー | 抗アポトーシスＢｃｌ阻害剤として有用な置換スルホンアミド |
| US9126980B2 (en) * | 2011-12-23 | 2015-09-08 | Novartis Ag | Compounds for inhibiting the interaction of BCL2 with binding partners |
| EP2794592A1 (en) * | 2011-12-23 | 2014-10-29 | Novartis AG | Compounds for inhibiting the interaction of bcl2 with binding partners |
| BR112014015308A8 (pt) * | 2011-12-23 | 2017-06-13 | Novartis Ag | compostos para inibição da interação de bcl2 com contrapartes de ligação |
| WO2013096051A1 (en) * | 2011-12-23 | 2013-06-27 | Novartis Ag | Compounds for inhibiting the interaction of bcl2 with binding partners |
| EP2794591A1 (en) * | 2011-12-23 | 2014-10-29 | Novartis AG | Compounds for inhibiting the interaction of bcl2 with binding partners |
| FR2986002B1 (fr) | 2012-01-24 | 2014-02-21 | Servier Lab | Nouveaux derives d'indolizine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
-
2013
- 2013-07-23 FR FR1357277A patent/FR3008978A1/fr not_active Withdrawn
-
2014
- 2014-07-08 UY UY35653A patent/UY35653A/es unknown
- 2014-07-21 AR ARP140102679A patent/AR099914A1/es unknown
- 2014-07-22 LT LTEP14758604.4T patent/LT3027602T/lt unknown
- 2014-07-22 CN CN201480041559.7A patent/CN105408321B/zh not_active Expired - Fee Related
- 2014-07-22 PL PL14758604T patent/PL3027602T3/pl unknown
- 2014-07-22 HU HUE14758604A patent/HUE039507T2/hu unknown
- 2014-07-22 WO PCT/FR2014/051884 patent/WO2015011396A1/fr not_active Ceased
- 2014-07-22 AU AU2014294866A patent/AU2014294866B2/en not_active Ceased
- 2014-07-22 SG SG11201600004SA patent/SG11201600004SA/en unknown
- 2014-07-22 MX MX2016000900A patent/MX364479B/es active IP Right Grant
- 2014-07-22 KR KR1020167004577A patent/KR102337149B1/ko not_active Expired - Fee Related
- 2014-07-22 JP JP2016528587A patent/JP6458028B2/ja not_active Expired - Fee Related
- 2014-07-22 DK DK14758604.4T patent/DK3027602T3/en active
- 2014-07-22 UA UAA201601398A patent/UA117020C2/uk unknown
- 2014-07-22 SI SI201430784T patent/SI3027602T1/en unknown
- 2014-07-22 EP EP14758604.4A patent/EP3027602B1/fr active Active
- 2014-07-22 TW TW103125162A patent/TW201504224A/zh unknown
- 2014-07-22 BR BR112016001333-6A patent/BR112016001333B1/pt not_active IP Right Cessation
- 2014-07-22 CA CA2917965A patent/CA2917965C/fr active Active
- 2014-07-22 EA EA201600121A patent/EA028609B1/ru unknown
- 2014-07-22 NZ NZ715847A patent/NZ715847A/en not_active IP Right Cessation
- 2014-07-22 EP EP16201228.0A patent/EP3168217A1/fr not_active Withdrawn
- 2014-07-22 HK HK16106759.0A patent/HK1218753A1/zh unknown
- 2014-07-22 RU RU2016106002A patent/RU2693404C2/ru active
- 2014-07-22 ES ES14758604.4T patent/ES2687475T3/es active Active
- 2014-07-22 HR HRP20181333TT patent/HRP20181333T1/hr unknown
- 2014-07-22 RS RS20180839A patent/RS57545B1/sr unknown
- 2014-07-22 PT PT147586044T patent/PT3027602T/pt unknown
- 2014-07-22 US US14/905,877 patent/US9765056B2/en not_active Expired - Fee Related
-
2016
- 2016-01-12 ZA ZA2016/00415A patent/ZA201600415B/en unknown
-
2017
- 2017-08-14 US US15/676,154 patent/US10662173B2/en active Active
-
2018
- 2018-07-19 CY CY20181100757T patent/CY1120475T1/el unknown
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