|
DE59310252D1
(de)
|
1992-02-05 |
2002-01-24 |
Boehringer Ingelheim Pharma |
Neue Amiderivate, ihre Herstellung und Verwendung als Arzneimittel mit LTB4-antagonistischer Wirkung
|
|
CA2136999C
(en)
|
1993-04-07 |
2004-05-11 |
Takafumi Fujioka |
Peripheral vasodilating agent containing piperidine derivative as active ingredient
|
|
NZ277556A
(en)
|
1993-12-27 |
1997-06-24 |
Eisai Co Ltd |
N-phenyl(alkyl)- and n-pyridyl(alkyl)anthranilic acid derivatives; intermediates
|
|
GB9500580D0
(en)
|
1995-01-12 |
1995-03-01 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
US5763618A
(en)
|
1995-05-12 |
1998-06-09 |
Konica Corporation |
Manufacturing method of sulfides
|
|
DE19545878A1
(de)
|
1995-12-08 |
1997-06-12 |
Basf Ag |
Pyridylcarbamate, Verfahren und Zwischenprodukte zu ihrer Herstellung und ihre Verwendung
|
|
DE69717268T2
(de)
|
1996-02-22 |
2003-09-04 |
Bristol-Myers Squibb Pharma Co., Wilmington |
M-amidinophenyl-analoga als faktor-xa-inhibitoren
|
|
WO1997036886A1
(en)
|
1996-04-03 |
1997-10-09 |
Merck & Co., Inc. |
Inhibitors of farnesyl-protein transferase
|
|
CN1246847A
(zh)
|
1996-12-23 |
2000-03-08 |
杜邦药品公司 |
作为Xa因子抑制剂的含氮杂芳族化合物
|
|
US6187797B1
(en)
|
1996-12-23 |
2001-02-13 |
Dupont Pharmaceuticals Company |
Phenyl-isoxazoles as factor XA Inhibitors
|
|
US6020357A
(en)
|
1996-12-23 |
2000-02-01 |
Dupont Pharmaceuticals Company |
Nitrogen containing heteroaromatics as factor Xa inhibitors
|
|
ES2196396T3
(es)
|
1996-12-23 |
2003-12-16 |
Bristol Myers Squibb Pharma Co |
Compuestos heteroaromaticos de 5 miembros conteniendo oxigeno o azufre como inhibidores del factor xa.
|
|
HUP0003906A2
(hu)
|
1997-06-19 |
2001-05-28 |
Du Pont Pharmaceuticals Co. |
Xa faktort gátló hatású heterociklusos vegyületek és ezeket tartalmazó gyógyszerkészítmények
|
|
US6339099B1
(en)
|
1997-06-20 |
2002-01-15 |
Dupont Pharmaceuticals Company |
Guanidine mimics as factor Xa inhibitors
|
|
EP1000059B1
(en)
|
1997-07-30 |
2004-09-29 |
Wyeth |
Tricyclic vasopressin agonists
|
|
US6511974B1
(en)
|
1997-07-30 |
2003-01-28 |
Wyeth |
Tricyclic vasopressin agonists
|
|
JP4338305B2
(ja)
|
1997-07-30 |
2009-10-07 |
ワイス |
三環系バソプレシンアゴニスト
|
|
EP1076641A1
(en)
|
1998-04-29 |
2001-02-21 |
Vertex Pharmaceuticals Incorporated |
Inhibitors of impdh enzyme
|
|
US6121271A
(en)
|
1998-05-12 |
2000-09-19 |
American Home Products Corporation |
Naphtho[2,3-B]heteroar-4-yl derivatives
|
|
EP1077968A1
(en)
|
1998-05-12 |
2001-02-28 |
American Home Products Corporation |
Naphtho[2,3-b]heteroar-4-yl derivatives
|
|
JP2000109465A
(ja)
*
|
1998-08-05 |
2000-04-18 |
Nippon Soda Co Ltd |
フェニルピラゾ―ル化合物、製法及び抗高脂血症薬
|
|
EP1127054A4
(en)
|
1998-10-29 |
2006-11-02 |
Bristol Myers Squibb Co |
INHIBITORS OF IMPDH ENZYME
|
|
WO2000029399A1
(en)
|
1998-11-12 |
2000-05-25 |
Boehringer Ingelheim (Canada) Ltd. |
Antiherpes compounds
|
|
PT1149096E
(pt)
|
1999-02-04 |
2003-03-31 |
Wyeth Corp |
N-oxidos de piridina triciclicos agonistas de vasopressina
|
|
JP2000256358A
(ja)
|
1999-03-10 |
2000-09-19 |
Yamanouchi Pharmaceut Co Ltd |
ピラゾール誘導体
|
|
PT1177187E
(pt)
|
1999-04-28 |
2007-09-03 |
Sanofi Aventis Deutschland |
Derivados ácidos de di-arilo como ligados do receptor ppar.
|
|
MXPA02003191A
(es)
|
1999-09-27 |
2002-09-30 |
American Cyanamid Co |
Formulacion agonista de vasopresina y proceso para elaborar la misma.
|
|
ATE376996T1
(de)
|
2000-01-13 |
2007-11-15 |
Amgen Inc |
Antibakterielle mittel
|
|
AU2001243598A1
(en)
|
2000-03-13 |
2001-09-24 |
Pharmacia Corporation |
Polycyclic aryl and heteroaryl substituted benzenes useful for selective inhibition of the coagulation cascade
|
|
MY138097A
(en)
|
2000-03-22 |
2009-04-30 |
Du Pont |
Insecticidal anthranilamides
|
|
AU2001273040A1
(en)
|
2000-06-27 |
2002-01-08 |
Du Pont Pharmaceuticals Company |
Factor xa inhibitors
|
|
DE10063008A1
(de)
|
2000-12-16 |
2002-06-20 |
Merck Patent Gmbh |
Carbonsäureamidderivate
|
|
AU2002248432A1
(en)
|
2001-02-14 |
2002-08-28 |
Sankyo Company, Limited |
Oxazole derivatives, their preparation and their use as cytokine inhibitors
|
|
CA2437840A1
(en)
|
2001-03-05 |
2002-09-12 |
E.I. Du Pont De Nemours |
Heterocyclic diamide invertebrate pest control agents
|
|
DE10110749A1
(de)
|
2001-03-07 |
2002-09-12 |
Bayer Ag |
Substituierte Aminodicarbonsäurederivate
|
|
DE10111842A1
(de)
|
2001-03-13 |
2002-09-19 |
Boehringer Ingelheim Pharma |
Antithrombotische Carbonsäureamide, deren Herstellung und deren Verwendung als Arzneimittel
|
|
WO2002076959A1
(en)
|
2001-03-23 |
2002-10-03 |
Takeda Chemical Industries, Ltd. |
Five-membered heterocyclic alkanoic acid derivative
|
|
CA2447475A1
(en)
|
2001-05-25 |
2002-12-05 |
Chu-Biao Xue |
Hydantion derivatives as inhibitors of matrix metalloproteinases
|
|
DE10130374A1
(de)
|
2001-06-23 |
2003-01-02 |
Boehringer Ingelheim Pharma |
Substituierte N-Acyl-anilinderivate, deren Herstellung und deren Verwendung als Arzneimittel
|
|
PL367677A1
(en)
|
2001-06-28 |
2005-03-07 |
Smithkline Beecham P.L.C. |
N-aroyl cyclic amine derivatives as orexin receptor antagonists
|
|
GB0115862D0
(en)
|
2001-06-28 |
2001-08-22 |
Smithkline Beecham Plc |
Compounds
|
|
WO2003004474A1
(en)
|
2001-07-06 |
2003-01-16 |
Syngenta Participations Ag |
Pesticidally active aminoacetonitriles
|
|
MXPA04001088A
(es)
|
2001-08-03 |
2004-05-20 |
Vertex Pharma |
Derivados de pirazol como inhibidores de cinasa y uso de los mismos.
|
|
GB0124463D0
(en)
|
2001-10-11 |
2001-12-05 |
Smithkline Beecham Plc |
Compounds
|
|
SE0103644D0
(sv)
|
2001-11-01 |
2001-11-01 |
Astrazeneca Ab |
Therapeutic isoquinoline compounds
|
|
US6984735B2
(en)
|
2001-12-03 |
2006-01-10 |
Wyeth |
Process for making an aldehyde
|
|
AU2003220401A1
(en)
|
2002-03-18 |
2003-10-08 |
Bristol-Myers Squibb Company |
Uracil derivatives as inhibitors of tnf-alpha converting enzyme (tace) and matrix metalloproteinases
|
|
EP1487796A4
(en)
|
2002-03-28 |
2005-11-16 |
Neurogen Corp |
SUBSTITUTED BIARYLAMIDES AS MODULATORS OF THE C5A RECEPTOR
|
|
WO2004000788A1
(en)
|
2002-06-19 |
2003-12-31 |
Bristol-Myers Squibb Company |
Ureido-substituted aniline compounds useful as serine protease inhibitors
|
|
US20040044041A1
(en)
|
2002-08-06 |
2004-03-04 |
Kuduk Scott D. |
2-(Biarylalkyl)amino-3-(cyanoalkanoylamino)pyridine derivatives
|
|
WO2004016592A1
(en)
|
2002-08-14 |
2004-02-26 |
Ppd Discovery, Inc. |
Prenylation inhibitors and methods of their synthesis and use
|
|
WO2004033632A2
(en)
|
2002-10-04 |
2004-04-22 |
Bristol-Myers Squibb Company |
Hydantoin derivatives as inhibitors of matrix metalloproteinases and/or tnf-alpha converting enzyme (tace)
|
|
US20040082641A1
(en)
|
2002-10-28 |
2004-04-29 |
Rytved Klaus Asger |
Use of glycogen phosphorylase inhibitors for treatment of cardiovascular diseases
|
|
CA2505361A1
(en)
|
2002-11-11 |
2004-05-27 |
Bayer Healthcare Ag |
Phenyl or heteroaryl amino alkane derivatives as ip receptor antagonist
|
|
JP2004161716A
(ja)
|
2002-11-15 |
2004-06-10 |
Takeda Chem Ind Ltd |
Jnk阻害剤
|
|
EP1594512A4
(en)
|
2003-02-11 |
2007-07-11 |
Kemia Inc |
COMPOUNDS FOR THE TREATMENT OF VIRUS INFECTIONS
|
|
DE10306250A1
(de)
|
2003-02-14 |
2004-09-09 |
Aventis Pharma Deutschland Gmbh |
Substituierte N-Arylheterozyklen, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
|
|
EA200501607A1
(ru)
|
2003-04-14 |
2006-06-30 |
ДЗЕ ИНСТИТЬЮТС ФОР ФАРМАСЬЮТИКАЛ ДИСКАВЕРИ, ЭлЭлСи |
Замещённые фенилалкановые кислоты
|
|
WO2005000813A1
(en)
|
2003-05-30 |
2005-01-06 |
Imclone Systems Incorporated |
Heteroarylamino-phenylketone derivatives and their use as kinase inhibitors
|
|
CA2534263A1
(en)
|
2003-08-01 |
2005-02-10 |
Nippon Soda Co., Ltd. |
Phenylazole compounds, production process and antioxidants
|
|
BRPI0413785A
(pt)
|
2003-08-21 |
2006-11-07 |
Osi Pharm Inc |
composto, composição, e, método de tratamento de distúrbio hiperproliferativo
|
|
US7485658B2
(en)
|
2003-08-21 |
2009-02-03 |
Osi Pharmaceuticals, Inc. |
N-substituted pyrazolyl-amidyl-benzimidazolyl c-Kit inhibitors
|
|
EP1663204B1
(en)
|
2003-08-29 |
2014-05-07 |
Exelixis, Inc. |
C-kit modulators and methods of use
|
|
EP1786815B1
(en)
|
2003-09-10 |
2011-08-24 |
Virochem Pharma Inc. |
Spiro compounds and methods for the modulation of chemokine receptor activity
|
|
US7211671B2
(en)
|
2003-10-01 |
2007-05-01 |
Bristol Myers Squibb Company |
Substituted 1,3-dihydro-imidazol-2-one and 1,3-dihydro-imidazol-2-thione derivatives as inhibitors of matrix metalloproteinases and/or TNF-α converting enzyme (TACE)
|
|
CA2541458C
(en)
|
2003-10-08 |
2011-09-20 |
Eli Lilly And Company |
Pyrrole and pyrazole derivatives as potentiators of glutamate receptors
|
|
WO2005039494A2
(en)
|
2003-10-21 |
2005-05-06 |
Message Pharmaceuticals, Inc. |
Inhibitors of rnase p proteins as antibacterial compounds
|
|
EP1713775A4
(en)
*
|
2004-01-30 |
2009-08-12 |
Smithkline Beecham Corp |
CHEMICAL COMPOUNDS
|
|
EP1574502A1
(en)
|
2004-03-08 |
2005-09-14 |
Novartis AG |
Use of pyrimidine compounds in the preparation of parasiticides
|
|
JP2008512378A
(ja)
|
2004-09-03 |
2008-04-24 |
セルジーン・コーポレーション |
置換複素環式化合物及びその使用
|
|
CA2585555A1
(en)
|
2004-10-28 |
2006-05-11 |
The Institutes For Pharmaceutical Discovery, Llc |
Substituted phenylalkanoic acids
|
|
WO2006068933A2
(en)
|
2004-12-21 |
2006-06-29 |
Merck & Co., Inc. |
Mitotic kinesin inhibitors
|
|
US8329703B2
(en)
|
2005-02-15 |
2012-12-11 |
Xtl Biopharmaceuticals Ltd. |
Pyrazole compounds
|
|
EP1863756A1
(en)
|
2005-03-24 |
2007-12-12 |
Janssen Pharmaceutica N.V. |
Biaryl derived amide modulators of vanilloid vr1 receptor
|
|
FR2887548B1
(fr)
|
2005-06-27 |
2007-09-21 |
Sanofi Aventis Sa |
Derives de 4,5-diarylpyrrole, leur preparation et leur application en therapeutique
|
|
US8569352B2
(en)
|
2005-06-27 |
2013-10-29 |
Exelixis Patent Company Llc |
Imidazole based LXR modulators
|
|
FR2888237B1
(fr)
|
2005-07-08 |
2007-08-31 |
Sanofi Aventis Sa |
Derives de n-[(4,5-diphenylpyrimidin-2-yl)methyl] amine, leur preparation et leur application en therapeutique
|
|
AR057450A1
(es)
|
2005-07-12 |
2007-12-05 |
Sanofi Aventis |
Derivados de n-[(1,2-difenil-1h-imidazol-4- il)metil]amina su preparacion y su aplicacion en terapeutica
|
|
MX2008002540A
(es)
|
2005-08-23 |
2008-03-14 |
Irm Llc |
Compuestos inmunosupresores y composiciones.
|
|
US7906652B2
(en)
|
2005-11-28 |
2011-03-15 |
Merck Sharp & Dohme Corp. |
Heterocycle-substituted 3-alkyl azetidine derivatives
|
|
FR2894579B1
(fr)
|
2005-12-12 |
2008-01-18 |
Sanofi Aventis Sa |
Derives diaryltriazolmethylamine, leur preparation et leur application en therapeutique.
|
|
FR2894578B1
(fr)
|
2005-12-12 |
2008-02-01 |
Sanofi Aventis Sa |
Derives heterocycliques, leur preparation et leur application en therapeutique.
|
|
EP1971602A4
(en)
|
2005-12-20 |
2009-11-11 |
Merck & Co Inc |
AGONISTS OF THE NIACIN RECEPTOR, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND TREATMENT PROCEDURES
|
|
KR20080083680A
(ko)
|
2005-12-23 |
2008-09-18 |
스미스클라인 비참 코포레이션 |
오로라 키나제의 아자인돌 억제제
|
|
WO2007098169A1
(en)
|
2006-02-21 |
2007-08-30 |
Amgen Inc. |
Cinnoline derivatives as phosphodiesterase 10 inhibitors
|
|
AU2012200157B2
(en)
|
2006-05-25 |
2014-08-21 |
Synta Pharmaceuticals Corp. |
Method for treating proliferative disorders associated with protooncogene products
|
|
WO2007146230A2
(en)
|
2006-06-14 |
2007-12-21 |
Merck & Co., Inc. |
Non-nucleoside reverse transcriptase inhibitors
|
|
US9108948B2
(en)
|
2006-06-23 |
2015-08-18 |
Abbvie Inc. |
Cyclopropyl amine derivatives
|
|
MX2008015923A
(es)
|
2006-06-29 |
2009-01-13 |
Hoffmann La Roche |
Derivados de bencimidazol, metodo para su produccion, su uso como agonistas fxr y preparaciones farmaceuticas que los contienen.
|
|
BRPI0712795A2
(pt)
|
2006-07-07 |
2012-09-04 |
Boehringer Ingelheim Int |
derivados de heteroarila substituìdos com fenila e uso dos mesmos como agentes antitumorais
|
|
WO2008016643A2
(en)
|
2006-08-01 |
2008-02-07 |
Cytokinetics, Incorporated |
Certain chemical entities, compositions, and methods
|
|
FR2904827B1
(fr)
|
2006-08-11 |
2008-09-19 |
Sanofi Aventis Sa |
Derives de 5,6-bisaryl-2-pyridine-carboxamide, leur preparation et leur application en therapeutique comme antiganistes des recepteurs a l'urotensine ii
|
|
AU2007294149A1
(en)
|
2006-09-06 |
2008-03-13 |
F. Hoffmann-La Roche Ag |
Heteroaryl derivatives as protein kinase inhibitors
|
|
WO2008057246A2
(en)
|
2006-10-26 |
2008-05-15 |
Synta Pharmaceuticals Corp. |
Method for treating inflammatory disorders
|
|
WO2008064317A1
(en)
|
2006-11-22 |
2008-05-29 |
University Of Medicine And Dentistry Of New Jersey |
Lipophilic opioid receptor active compounds
|
|
WO2008064318A2
(en)
|
2006-11-22 |
2008-05-29 |
University Of Medicine And Dentistry Of New Jersey |
Peripheral opioid receptor active compounds
|
|
WO2008064310A2
(en)
|
2006-11-22 |
2008-05-29 |
University Of Medicine And Dentistry Of New Jersey |
Mixed opioid receptor active compounds
|
|
ES2401129T3
(es)
|
2006-12-19 |
2013-04-17 |
F. Hoffmann-La Roche Ag |
Derivados de heteroaril-pirrolidinil- y -piperidinil-cetona
|
|
EP2079694B1
(en)
|
2006-12-28 |
2017-03-01 |
Rigel Pharmaceuticals, Inc. |
N-substituted-heterocycloalkyloxybenzamide compounds and methods of use
|
|
FR2911136B1
(fr)
|
2007-01-05 |
2009-02-20 |
Sanofi Aventis Sa |
Derives de n-(4-cyano-1h-pyrazol-3-yl)methylamine substitues leur preparation et leur application en therapeutique.
|
|
CA2674530C
(en)
|
2007-01-12 |
2014-09-16 |
Banyu Pharmaceutical Co., Ltd. |
Spirochromanon derivatives
|
|
TW200838516A
(en)
|
2007-01-31 |
2008-10-01 |
Merck & Co Inc |
Substituted pyrano[2,3-B]pyridine derivatives as cannabinoid-1 receptor modulators
|
|
JP2008195655A
(ja)
|
2007-02-14 |
2008-08-28 |
Kitasato Institute |
糖尿病白内障の治療剤
|
|
WO2008137102A2
(en)
|
2007-05-04 |
2008-11-13 |
Torreypines Therapeutics, Inc. |
Methods of modulating amyloid beta and compounds useful therefor
|
|
EP1992625A1
(en)
|
2007-05-16 |
2008-11-19 |
Sanofi-Aventis |
Arylamide pyrimidone compounds
|
|
AU2008253311A1
(en)
|
2007-05-18 |
2008-11-27 |
Bayer Schering Pharma Aktiengesellshaft |
Inhibitors of hypoxia inducible factor (HIF) useful for treating hyper-proliferative disorders and diseases associated with angiogenesis
|
|
HRP20120240T1
(hr)
|
2007-05-23 |
2012-04-30 |
Merck Sharp & Dohme Corp. |
Piridil piperidin antagonisti receptora za oreksin
|
|
AR066834A1
(es)
|
2007-06-06 |
2009-09-16 |
Janssen Pharmaceutica Nv |
Espirobenzoazepanos como antagonistas de vasopresina, composiciones farmaceuticas que los contienen, proceso de preparacion y usos para el tratamiento de afecciones cardiacas, renales y del sistema nervioso central.
|
|
EP2002838A1
(de)
|
2007-06-13 |
2008-12-17 |
Bayer Schering Pharma AG |
Verwendung von Aryl/Hetarylamid-Derivaten als Modulatoren des EP2-Rezeptors
|
|
WO2008152138A2
(de)
|
2007-06-15 |
2008-12-18 |
Basf Se |
Verfahren zur herstellung difluormethylsubstituierter pyrazolverbindungen
|
|
EP2176249A2
(en)
|
2007-07-02 |
2010-04-21 |
Boehringer Ingelheim International GmbH |
New chemical compounds
|
|
WO2009015208A1
(en)
|
2007-07-23 |
2009-01-29 |
Replidyne, Inc. |
Antibacterial amide and sulfonamide substituted heterocyclic urea compounds
|
|
US20090053192A1
(en)
|
2007-08-10 |
2009-02-26 |
Burnham Institute For Medical Research |
Tissue-nonspecific alkaline phosphatase (tnap) activators and uses thereof
|
|
EP2193119B1
(en)
|
2007-08-27 |
2014-01-01 |
Abbvie Deutschland GmbH & Co. KG |
4-(4-pyridinyl)-benzamides and their use as rock activity modulators
|
|
TW200920357A
(en)
|
2007-09-10 |
2009-05-16 |
Curis Inc |
HSP90 inhibitors containing a zinc binding moiety
|
|
WO2009036051A1
(en)
|
2007-09-10 |
2009-03-19 |
Curis, Inc. |
Bcl-2 inhibitors containing a zinc binding moiety
|
|
KR20090033583A
(ko)
|
2007-10-01 |
2009-04-06 |
주식회사 엘지생명과학 |
글라이신 아릴 아마이드를 포함하는 신규한베타-세크리타제 저해용 화합물
|
|
CA2702482C
(en)
|
2007-10-17 |
2012-11-27 |
Sanofi-Aventis |
Substituted n-phenyl-bipyrrolidine carboxamides and therapeutic use thereof
|
|
TWI440638B
(zh)
|
2007-10-30 |
2014-06-11 |
Otsuka Pharma Co Ltd |
雜環化合物及其藥學組成物
|
|
US20100280049A1
(en)
|
2007-11-06 |
2010-11-04 |
Amira Pharmaceuticals, Inc. |
Antagonists of pgd2 receptors
|
|
CN101945868A
(zh)
|
2007-12-11 |
2011-01-12 |
先灵公司 |
γ分泌酶调节剂
|
|
WO2009079008A1
(en)
*
|
2007-12-19 |
2009-06-25 |
Yangbo Feng |
Benzopyrans and analogs as rho kinase inhibitors
|
|
JP2011507850A
(ja)
*
|
2007-12-21 |
2011-03-10 |
ザ スクリプス リサーチ インスティチュート |
Rhoキナーゼインヒビターとしてのアニリドおよびアナログ
|
|
CN101538245B
(zh)
|
2008-03-18 |
2011-02-16 |
中国科学院上海药物研究所 |
一类哒嗪酮类化合物及其制备方法和制备药物的用途
|
|
CA2721060A1
(en)
|
2008-04-09 |
2009-10-15 |
Infinity Pharmaceuticals, Inc. |
Inhibitors of fatty acid amide hydrolase
|
|
WO2009131173A1
(ja)
|
2008-04-23 |
2009-10-29 |
協和発酵キリン株式会社 |
2-アミノキナゾリン誘導体
|
|
CN102088855A
(zh)
|
2008-05-08 |
2011-06-08 |
百时美施贵宝公司 |
2-芳基甘氨酰胺衍生物
|
|
CN101597278B
(zh)
|
2008-06-04 |
2013-04-17 |
中国中化股份有限公司 |
酰胺类化合物及其制备与应用
|
|
NZ624345A
(en)
|
2008-06-27 |
2016-07-29 |
Celgene Avilomics Res Inc |
2,4-disubstituted pyrimidines useful as kinase inhibitors
|
|
US8623238B2
(en)
|
2008-06-27 |
2014-01-07 |
Transitions Optical, Inc. |
Mesogenic stabilizers
|
|
US8338439B2
(en)
|
2008-06-27 |
2012-12-25 |
Celgene Avilomics Research, Inc. |
2,4-disubstituted pyrimidines useful as kinase inhibitors
|
|
WO2010036316A1
(en)
|
2008-09-24 |
2010-04-01 |
Yangbo Feng |
Urea and carbamate compounds and analogs as kinase inhibitors
|
|
CA2739303A1
(en)
|
2008-10-01 |
2010-04-08 |
Synta Pharmaceuticals Corp. |
Compounds for inflammation and immune-related uses
|
|
US8829001B2
(en)
|
2008-10-10 |
2014-09-09 |
The Institute of Pharmacology and Toxicology Academy of Military Medical Science P.L.A. China |
Dopamine D3 receptor ligands and preparation and medical uses of the same
|
|
US8367679B2
(en)
|
2008-12-09 |
2013-02-05 |
Merck Sharp & Dohme Corp. |
Biaryl carboxamides
|
|
CA2746943A1
(en)
|
2008-12-18 |
2010-07-15 |
Boehringer Ingelheim International Gmbh |
Serotonin 5-ht2b receptor inhibitors
|
|
WO2010075290A1
(en)
|
2008-12-22 |
2010-07-01 |
President And Fellows Of Harvard College |
Unsaturated heterocyclic inhibitors of necroptosis
|
|
US8785468B2
(en)
|
2009-02-13 |
2014-07-22 |
Amgen Inc. |
Phenylalanine amide derivatives useful for treating insulin-related diseases and conditions
|
|
JP5688918B2
(ja)
|
2009-04-28 |
2015-03-25 |
大塚製薬株式会社 |
医薬組成物
|
|
WO2010129848A2
(en)
|
2009-05-08 |
2010-11-11 |
Takeda Pharmaceutical Company Limited |
2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxamides
|
|
CN102573473B
(zh)
|
2009-06-09 |
2015-05-27 |
加利福尼亚资本权益有限责任公司 |
用作hedgehog 信号转导抑制剂的异喹啉、喹啉和喹唑啉衍生物
|
|
AR077033A1
(es)
|
2009-06-11 |
2011-07-27 |
Hoffmann La Roche |
Compuestos inhibidores de las quinasas de janus y su uso en el tratamiento de enfermedades inmunologicas
|
|
EP2477625A4
(en)
|
2009-09-14 |
2012-10-24 |
Phusis Therapeutics Inc |
PHARMACEUTICAL COMPOSITIONS AND FORMULATIONS COMPRISING PLECKSTRINE HOMOLOGY DOMAIN INHIBITORS AND METHODS OF USE
|
|
WO2011041593A1
(en)
|
2009-09-30 |
2011-04-07 |
University Of Kansas |
Novobiocin analogues and treatment of polycystic kidney disease
|
|
US8377970B2
(en)
|
2009-10-08 |
2013-02-19 |
Rhizen Pharmaceuticals Sa |
Modulators of calcium release-activated calcium channel
|
|
US8993612B2
(en)
|
2009-10-08 |
2015-03-31 |
Rhizen Pharmaceuticals Sa |
Modulators of calcium release-activated calcium channel and methods for treatment of non-small cell lung cancer
|
|
CA2778886C
(en)
|
2009-11-10 |
2014-01-07 |
Pfizer Inc. |
N1-pyrazolospiroketone acetyl-coa carboxylase inhibitors
|
|
CA2778316A1
(en)
|
2009-11-10 |
2011-05-19 |
Pfizer Inc. |
N-2 pyrazolospiroketone acetyl-coa carboxylase inhibitors
|
|
US8394858B2
(en)
|
2009-12-03 |
2013-03-12 |
Novartis Ag |
Cyclohexane derivatives and uses thereof
|
|
HUE038064T2
(hu)
|
2009-12-18 |
2018-10-29 |
Ogeda Sa |
Pirrolidin karboxilsav származékok, mint G-protein kapcsolat receptor 43 (GPR43) agonistái, gyógyszerészeti készítmény és felhasználási eljárások metabolikus rendellenességek kezelésében
|
|
JP2013047188A
(ja)
|
2009-12-24 |
2013-03-07 |
Nippon Chemiphar Co Ltd |
Gpr119作動薬
|
|
WO2011088181A1
(en)
|
2010-01-13 |
2011-07-21 |
Tempero Pharmaceuticals, Inc. |
Compounds and methods
|
|
WO2011088031A1
(en)
|
2010-01-13 |
2011-07-21 |
Glaxosmithkline Llc |
Compounds and methods
|
|
MX2012008141A
(es)
|
2010-01-13 |
2012-08-03 |
Glaxosmithkline Llc |
Compuestos y metodos.
|
|
US20190192510A1
(en)
|
2010-02-01 |
2019-06-27 |
Nippon Chemiphar Co., Ltd. |
Gpr119 agonist
|
|
US9206125B2
(en)
|
2010-02-10 |
2015-12-08 |
Public University Corporation Yokohama City University |
Use of compound binding to mSin3B that specifically binds to neuron restrictive silencer factor (NRSF)
|
|
WO2011106632A1
(en)
|
2010-02-26 |
2011-09-01 |
Millennium Pharmaceuticals, Inc. |
Substituted hydroxamic acids and uses thereof
|
|
US8354410B2
(en)
|
2010-03-11 |
2013-01-15 |
Bristol-Meyers Squibb Company |
Compounds for the treatment of hepatitis C
|
|
JP2013522192A
(ja)
|
2010-03-11 |
2013-06-13 |
ブリストル−マイヤーズ スクイブ カンパニー |
C型肝炎の処置のための化合物
|
|
WO2011140425A1
(en)
|
2010-05-06 |
2011-11-10 |
Vertex Pharmaceuticals Incorporated |
Heterocyclic chromene-spirocyclic piperidine amides as modulators of ion channels
|
|
WO2011156557A2
(en)
|
2010-06-11 |
2011-12-15 |
Thomas James B |
Compounds active at the neurotensin receptor
|
|
US8697911B2
(en)
|
2010-07-07 |
2014-04-15 |
Boehringer Ingelheim International Gmbh |
Rho kinase inhibitors
|
|
US9079880B2
(en)
|
2010-07-07 |
2015-07-14 |
Boehringer Ingelheim International Gmbh |
Rho kinase inhibitors
|
|
JP5749341B2
(ja)
|
2010-08-20 |
2015-07-15 |
ハチソン メディファーマ リミテッド |
ピロロピリミジン化合物およびその使用
|
|
WO2012040444A2
(en)
|
2010-09-24 |
2012-03-29 |
Bristol-Myers Squibb Company |
Treatment of patients with incipient alzheimer's disease
|
|
CN103327972A
(zh)
|
2010-10-11 |
2013-09-25 |
里兰斯坦福初级大学理事会 |
取代的苯甲酰胺及其用途
|
|
CN102451178A
(zh)
|
2010-10-29 |
2012-05-16 |
中国科学院上海药物研究所 |
二氢呋喃-2-酮类化合物在制备抗糖尿病及糖脂代谢药物中的用途
|
|
WO2012068210A1
(en)
|
2010-11-18 |
2012-05-24 |
Janssen Pharmaceutica Nv |
Pyridyl-thiazolyl inhibitors of pro-matrix metalloproteinase activation
|
|
RU2013127636A
(ru)
|
2010-11-22 |
2014-12-27 |
Аллерган, Инк. |
Новые соединения в качестве модуляторов рецепторов с терапевтической полезностью
|
|
EP2457900A1
(en)
|
2010-11-25 |
2012-05-30 |
Almirall, S.A. |
New pyrazole derivatives having CRTh2 antagonistic behaviour
|
|
SG190957A1
(en)
|
2010-12-01 |
2013-07-31 |
Nissan Chemical Ind Ltd |
Pyrazole compounds having therapeutic effect on multiple myeloma
|
|
US9212348B2
(en)
|
2010-12-01 |
2015-12-15 |
Nissan Chemical Industries, Ltd. |
Method for producing hematopoietic stem cells using pyrazole compounds
|
|
BR112013014019A2
(pt)
|
2010-12-07 |
2016-09-13 |
Amira Pharmaceuticals Inc |
antagonistas do receptor do ácido lisofosfatídico e seus usos
|
|
GB201021104D0
(en)
|
2010-12-13 |
2011-01-26 |
Univ Leuven Kath |
Novel compounds for the treatment of neurodegenerative diseases
|
|
TWI520964B
(zh)
|
2011-02-02 |
2016-02-11 |
維泰克斯製藥公司 |
作為離子通道調節劑之吡咯并吡-螺環哌啶醯胺
|
|
GB201104267D0
(en)
|
2011-03-14 |
2011-04-27 |
Cancer Rec Tech Ltd |
Pyrrolopyridineamino derivatives
|
|
AU2012236834B2
(en)
|
2011-03-28 |
2015-12-10 |
Mei Pharma, Inc |
(alpha- substituted aralkylamino and heteroarylalkylamino) pyrimidinyl and 1,3,5 -triazinyl benzimidazoles, pharmaceutical compositions containing them, and these compounds for use in treating proliferative diseases
|
|
US9616064B2
(en)
|
2011-03-30 |
2017-04-11 |
H. Lee Moffitt Cancer Center And Research Institute, Inc. |
Rho kinase inhibitors and methods of use
|
|
GB201107223D0
(en)
|
2011-04-29 |
2011-06-15 |
Amakem Nv |
Novel rock inhibitors
|
|
WO2012160464A1
(en)
|
2011-05-26 |
2012-11-29 |
Daiichi Sankyo Company, Limited |
Heterocyclic compounds as protein kinase inhibitors
|
|
CN104909997B
(zh)
|
2011-05-26 |
2017-04-12 |
Tf化学公司 |
芳基、杂芳基、o‑芳基和o‑杂芳基碳环糖家族
|
|
CA2835281A1
(en)
|
2011-05-31 |
2012-12-06 |
Theravance, Inc. |
Neprilysin inhibitors
|
|
KR20140051942A
(ko)
|
2011-07-12 |
2014-05-02 |
에프. 호프만-라 로슈 아게 |
아미노메틸 퀴놀론 화합물
|
|
JP5967092B2
(ja)
|
2011-07-29 |
2016-08-10 |
日本ゼオン株式会社 |
光学異方体の波長分散調整方法及び重合性組成物
|
|
US9365588B2
(en)
|
2011-11-04 |
2016-06-14 |
Vertex Pharmaceuticals Incorporated |
Benzoxazines as modulators of ion channels
|
|
JP6243908B2
(ja)
|
2012-08-23 |
2017-12-06 |
アリオス バイオファーマ インク. |
パラミクソウイルス感染症を治療するための化合物
|
|
WO2014079850A1
(en)
|
2012-11-23 |
2014-05-30 |
F. Hoffmann-La Roche Ag |
Substituted heterocyclic derivatives
|
|
CA2898440A1
(en)
|
2013-01-18 |
2014-07-24 |
Bristol-Myers Squibb Company |
Phthalazinones and isoquinolinones as rock inhibitors
|
|
AR094929A1
(es)
|
2013-02-28 |
2015-09-09 |
Bristol Myers Squibb Co |
Derivados de fenilpirazol como inhibidores potentes de rock1 y rock2
|
|
EP3016950B1
(en)
|
2013-07-02 |
2017-06-07 |
Bristol-Myers Squibb Company |
Tricyclic pyrido-carboxamide derivatives as rock inhibitors
|
|
CN105492444B
(zh)
|
2013-07-02 |
2018-09-07 |
百时美施贵宝公司 |
作为rock抑制剂的三环吡啶-甲酰胺衍生物
|
|
RU2016131875A
(ru)
|
2014-01-20 |
2018-02-26 |
Ф. Хоффманн-Ля Рош Аг |
Производные n-фениллактама, способные стимулировать нейрогенез, и их применение при лечении заболеваний нервной системы
|