JP2016507555A5 - - Google Patents
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- JP2016507555A5 JP2016507555A5 JP2015556930A JP2015556930A JP2016507555A5 JP 2016507555 A5 JP2016507555 A5 JP 2016507555A5 JP 2015556930 A JP2015556930 A JP 2015556930A JP 2015556930 A JP2015556930 A JP 2015556930A JP 2016507555 A5 JP2016507555 A5 JP 2016507555A5
- Authority
- JP
- Japan
- Prior art keywords
- antibody
- seq
- immunologically active
- active fragment
- sequence defined
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/US2013/024995 WO2013119714A1 (en) | 2012-02-06 | 2013-02-06 | Cd47 antibodies and methods of use thereof |
| US13/761,087 US9045541B2 (en) | 2012-02-06 | 2013-02-06 | CD47 antibodies and methods of use thereof |
| USPCT/US2013/024995 | 2013-02-06 | ||
| US13/761,087 | 2013-02-06 | ||
| US201361815219P | 2013-04-23 | 2013-04-23 | |
| US61/815,219 | 2013-04-23 | ||
| PCT/US2013/053818 WO2014123580A1 (en) | 2013-02-06 | 2013-08-06 | Non-platelet depleting and non-red blood cell depleting cd47 antibodies and methods of use thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018146460A Division JP6726238B2 (ja) | 2013-02-06 | 2018-08-03 | 血小板非減少性かつ赤血球非減少性ｃｄ４７抗体及びその使用方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2016507555A JP2016507555A (ja) | 2016-03-10 |
| JP2016507555A5 true JP2016507555A5 (enExample) | 2016-10-06 |
Family
ID=51300031
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015556930A Pending JP2016507555A (ja) | 2013-02-06 | 2013-08-06 | 血小板非減少性かつ赤血球非減少性ｃｄ４７抗体及びその使用方法 |
| JP2018146460A Active JP6726238B2 (ja) | 2013-02-06 | 2018-08-03 | 血小板非減少性かつ赤血球非減少性ｃｄ４７抗体及びその使用方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018146460A Active JP6726238B2 (ja) | 2013-02-06 | 2018-08-03 | 血小板非減少性かつ赤血球非減少性ｃｄ４７抗体及びその使用方法 |
Country Status (19)
| Country | Link |
|---|---|
| EP (2) | EP2953643B1 (enExample) |
| JP (2) | JP2016507555A (enExample) |
| KR (2) | KR102276974B1 (enExample) |
| CN (1) | CN105101997B (enExample) |
| AU (2) | AU2013377886B2 (enExample) |
| BR (1) | BR112015018851A2 (enExample) |
| CA (1) | CA2900468C (enExample) |
| CL (1) | CL2015002203A1 (enExample) |
| EA (1) | EA036963B1 (enExample) |
| ES (1) | ES2944477T3 (enExample) |
| IL (2) | IL240390B (enExample) |
| MX (2) | MX2015010115A (enExample) |
| NI (1) | NI201500103A (enExample) |
| NZ (1) | NZ710695A (enExample) |
| PE (1) | PE20151408A1 (enExample) |
| PH (1) | PH12015501729B1 (enExample) |
| SG (2) | SG10201706383XA (enExample) |
| WO (1) | WO2014123580A1 (enExample) |
| ZA (2) | ZA201505745B (enExample) |
Families Citing this family (66)
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| EA034778B1 (ru) | 2012-02-06 | 2020-03-19 | Инхибркс, Инк. | Антитела к cd47 и способы их применения |
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| CN112245586A (zh) | 2013-03-15 | 2021-01-22 | 小利兰·斯坦福大学托管委员会 | 用于实现治疗有效剂量的抗cd47剂的方法 |
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| US11472878B2 (en) | 2016-04-15 | 2022-10-18 | The Board Of Trustees Of The Leland Stanford Junior University | Methods for determining and achieving therapeutically effective doses of anti-CD47 agents in treatment of cancer |
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| CN106117354B (zh) * | 2016-06-24 | 2020-01-14 | 安徽未名细胞治疗有限公司 | 一种全人源抗CD47的全分子IgG抗体及其应用 |
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| CN107955071B (zh) * | 2016-10-18 | 2021-03-26 | 上海赛远生物科技有限公司 | 人源抗人cd47抗体及其编码基因与应用 |
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| WO2018075960A1 (en) | 2016-10-21 | 2018-04-26 | Tioma Therapeutics, Inc. | Therapeutic cd47 antibodies |
| PL3532497T3 (pl) | 2016-10-26 | 2024-11-04 | The Board Of Trustees Of The Leland Stanford Junior University | Zmodyfikowane regiony zawiasowe immunoglobuliny dla zmniejszania hemaglutynacji |
| US11779631B2 (en) | 2016-11-03 | 2023-10-10 | Pfizer Inc. | CD47 blockade therapy by HDAC inhibitors |
| CA3042581A1 (en) | 2016-11-03 | 2018-05-11 | Trillium Therapeutics Inc. | Enhancement of cd47 blockade therapy by proteasome inhibitors |
| US11352425B2 (en) | 2016-11-08 | 2022-06-07 | Absos, Llc | Anti-CD47 antibodies |
| CN108779179B (zh) * | 2016-11-28 | 2022-02-08 | 江苏恒瑞医药股份有限公司 | Cd47抗体、其抗原结合片段及其医药用途 |
| CN110325549B (zh) | 2016-12-09 | 2024-03-08 | 艾利妥 | 抗SIRPα抗体及其使用方法 |
| KR102607101B1 (ko) * | 2017-01-26 | 2023-11-29 | 제트엘아이피 홀딩 리미티드 | Cd47 항원 결합 유닛 및 그것의 사용 |
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| US20200347130A1 (en) * | 2017-11-10 | 2020-11-05 | Jiangsu Hengrui Medicine Co., Ltd. | CD96 Antibody, Antigen-Binding Fragment and Pharmaceutical use Thereof |
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| CN110577597B (zh) * | 2018-06-11 | 2021-10-22 | 康诺亚生物医药科技（成都）有限公司 | 一种阻断CD47和SIRPα相互作用的抗体 |
| WO2020043188A1 (zh) * | 2018-08-31 | 2020-03-05 | 南京圣和药业股份有限公司 | 抗cd47抗体及其应用 |
| AU2019336345A1 (en) | 2018-09-04 | 2021-04-15 | Pfizer Inc. | CD47 blockade with parp inhibition for disease treatment |
| EP3826676A4 (en) * | 2018-10-31 | 2022-05-04 | I-Mab Biopharma US Limited | NOVEL CD47 ANTIBODIES AND METHODS OF USE THEREOF |
| TW202104260A (zh) | 2019-04-05 | 2021-02-01 | 美商西建公司 | 腫瘤選擇性結合ｃｄ４７之抗體之工程 |
| US20200400662A1 (en) | 2019-06-07 | 2020-12-24 | ALX Oncology Inc. | Methods and reagents for reducing the interference of drugs that bind cd47 in serological assays |
| US10980836B1 (en) | 2019-12-11 | 2021-04-20 | Myeloid Therapeutics, Inc. | Therapeutic cell compositions and methods of manufacturing and use thereof |
| CN113461817B (zh) * | 2020-03-31 | 2025-04-18 | 苏州泽璟生物制药股份有限公司 | 一种抗人cd47抗体及其抗原结合片段、制备方法和应用 |
| TWI869582B (zh) * | 2020-04-10 | 2025-01-11 | 大陸商和記黃埔醫藥（上海）有限公司 | 抗ｃｄ４７抗體及其用途 |
| CN116171284A (zh) * | 2020-04-24 | 2023-05-26 | 维尔托索宾科公司 | 用于治疗cd47相关疾病的双特异性抗体 |
| EP4190813A4 (en) * | 2020-07-31 | 2025-02-12 | Bio-Thera Solutions, Ltd. | CD47 ANTIBODIES AND THEIR APPLICATION |
| JP2023549140A (ja) | 2020-11-04 | 2023-11-22 | マイエロイド・セラピューティクス，インコーポレーテッド | 操作されたキメラ融合タンパク質組成物およびその使用方法 |
| US20220196651A1 (en) | 2020-12-06 | 2022-06-23 | ALX Oncology Inc. | Multimers for reducing the interference of drugs that bind cd47 in serological assays |
| AU2021380853B2 (en) * | 2020-12-23 | 2024-10-10 | Guangdong Feipeng Pharmaceutical Co., Ltd. | Antibody targeting CD47 and application thereof |
| KR20230129481A (ko) * | 2021-01-08 | 2023-09-08 | 베이징 한미 파마슈티컬 컴퍼니 리미티드 | Cd47과 특이적으로 결합하는 항체 및 그 항원 결합단편 |
| KR20240013094A (ko) | 2021-03-17 | 2024-01-30 | 마이얼로이드 테라퓨틱스, 인크. | 조작된 키메라 융합 단백질 조성물 및 그의 사용 방법 |
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