ZA201505745B - Non-platelet depleting and non-red blood cell depleting cd47 antibodies and methods of use thereof - Google Patents

Non-platelet depleting and non-red blood cell depleting cd47 antibodies and methods of use thereof

Info

Publication number
ZA201505745B
ZA201505745B ZA2015/05745A ZA201505745A ZA201505745B ZA 201505745 B ZA201505745 B ZA 201505745B ZA 2015/05745 A ZA2015/05745 A ZA 2015/05745A ZA 201505745 A ZA201505745 A ZA 201505745A ZA 201505745 B ZA201505745 B ZA 201505745B
Authority
ZA
South Africa
Prior art keywords
depleting
antibodies
methods
red blood
blood cell
Prior art date
Application number
ZA2015/05745A
Other languages
English (en)
Inventor
Eckelman Brendan
Timmer John
Razai Amir
Deveraux Quinn
Jones Kyle
Lappe Mark
Original Assignee
Inhibrx Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/US2013/024995 external-priority patent/WO2013119714A1/en
Application filed by Inhibrx Llc filed Critical Inhibrx Llc
Publication of ZA201505745B publication Critical patent/ZA201505745B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2896—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/71—Decreased effector function due to an Fc-modification
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
ZA2015/05745A 2013-02-06 2015-08-11 Non-platelet depleting and non-red blood cell depleting cd47 antibodies and methods of use thereof ZA201505745B (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
PCT/US2013/024995 WO2013119714A1 (en) 2012-02-06 2013-02-06 Cd47 antibodies and methods of use thereof
US13/761,087 US9045541B2 (en) 2012-02-06 2013-02-06 CD47 antibodies and methods of use thereof
US201361815219P 2013-04-23 2013-04-23
PCT/US2013/053818 WO2014123580A1 (en) 2013-02-06 2013-08-06 Non-platelet depleting and non-red blood cell depleting cd47 antibodies and methods of use thereof

Publications (1)

Publication Number Publication Date
ZA201505745B true ZA201505745B (en) 2020-02-26

Family

ID=51300031

Family Applications (2)

Application Number Title Priority Date Filing Date
ZA2015/05745A ZA201505745B (en) 2013-02-06 2015-08-11 Non-platelet depleting and non-red blood cell depleting cd47 antibodies and methods of use thereof
ZA2019/05292A ZA201905292B (en) 2013-02-06 2019-08-12 Non-platelet depleting and non-red blood cell depleting cd47 antibodies and methods of use thereof

Family Applications After (1)

Application Number Title Priority Date Filing Date
ZA2019/05292A ZA201905292B (en) 2013-02-06 2019-08-12 Non-platelet depleting and non-red blood cell depleting cd47 antibodies and methods of use thereof

Country Status (19)

Country Link
EP (2) EP2953643B1 (enExample)
JP (2) JP2016507555A (enExample)
KR (2) KR102276974B1 (enExample)
CN (1) CN105101997B (enExample)
AU (2) AU2013377886B2 (enExample)
BR (1) BR112015018851A2 (enExample)
CA (1) CA2900468C (enExample)
CL (1) CL2015002203A1 (enExample)
EA (1) EA036963B1 (enExample)
ES (1) ES2944477T3 (enExample)
IL (2) IL240390B (enExample)
MX (2) MX2015010115A (enExample)
NI (1) NI201500103A (enExample)
NZ (1) NZ710695A (enExample)
PE (1) PE20151408A1 (enExample)
PH (1) PH12015501729A1 (enExample)
SG (2) SG10201706383XA (enExample)
WO (1) WO2014123580A1 (enExample)
ZA (2) ZA201505745B (enExample)

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