|
GB1454864A
(en)
|
1974-03-05 |
1976-11-03 |
Wyeth John & Brother Ltd |
Thioureas
|
|
PT72878B
(en)
|
1980-04-24 |
1983-03-29 |
Merck & Co Inc |
Process for preparing mannich-base hydroxamic acid pro-drugs for the improved delivery of non-steroidal anti-inflammatory agents
|
|
AU658646B2
(en)
|
1991-05-10 |
1995-04-27 |
Rhone-Poulenc Rorer International (Holdings) Inc. |
Bis mono-and bicyclic aryl and heteroaryl compounds which inhibit EGF and/or PDGF receptor tyrosine kinase
|
|
CA2090283A1
(en)
|
1992-02-28 |
1993-08-29 |
Nobuyuki Hamanaka |
Phenoxyacetic acid derivatives
|
|
US5516652A
(en)
|
1993-10-06 |
1996-05-14 |
Merck Frosst Canada Inc. |
DNA encoding prostaglandin receptor IP
|
|
EP0753528A4
(en)
|
1994-02-10 |
1999-03-10 |
Ono Pharmaceutical Co |
PROTAGLANDIN I 2? RECEPTOR
|
|
WO1996035713A1
(en)
|
1995-05-08 |
1996-11-14 |
Pfizer, Inc. |
Dipeptides which promote release of growth hormone
|
|
GB9622386D0
(en)
|
1996-10-28 |
1997-01-08 |
Sandoz Ltd |
Organic compounds
|
|
TWI242011B
(en)
|
1997-03-31 |
2005-10-21 |
Eisai Co Ltd |
1,4-substituted cyclic amine derivatives
|
|
US6166037A
(en)
|
1997-08-28 |
2000-12-26 |
Merck & Co., Inc. |
Pyrrolidine and piperidine modulators of chemokine receptor activity
|
|
DE19834044A1
(de)
|
1998-07-29 |
2000-02-03 |
Bayer Ag |
Neue substituierte Pyrazolderivate
|
|
DE19834047A1
(de)
|
1998-07-29 |
2000-02-03 |
Bayer Ag |
Substituierte Pyrazolderivate
|
|
UA71586C2
(en)
|
1998-12-04 |
2004-12-15 |
Smithkline Beecham Corp |
A vitronectin receptor antagonist
|
|
GB9913083D0
(en)
|
1999-06-04 |
1999-08-04 |
Novartis Ag |
Organic compounds
|
|
EP1175402B1
(en)
|
1999-05-04 |
2005-07-20 |
Schering Corporation |
Piperidine derivatives useful as ccr5 antagonists
|
|
TR200103214T2
(tr)
|
1999-05-04 |
2002-03-21 |
Schering Corporation |
CCR5 antagonistleri olarak yararlì piperazin trevleri.
|
|
GB9914255D0
(en)
|
1999-06-18 |
1999-08-18 |
Lilly Forschung Gmbh |
Pharmaceutical compounds
|
|
EG24179A
(en)
|
1999-09-07 |
2008-09-28 |
Smithkline Beecham Corp |
Vitronectin receptor antagonists
|
|
DE19943636A1
(de)
|
1999-09-13 |
2001-03-15 |
Bayer Ag |
Neuartige Dicarbonsäurederivate mit pharmazeutischen Eigenschaften
|
|
DE19943634A1
(de)
|
1999-09-13 |
2001-04-12 |
Bayer Ag |
Neuartige Dicarbonsäurederivate mit pharmazeutischen Eigenschaften
|
|
DE19943639A1
(de)
|
1999-09-13 |
2001-03-15 |
Bayer Ag |
Dicarbonsäurederivate mit neuartigen pharmazeutischen Eigenschaften
|
|
DE19943635A1
(de)
|
1999-09-13 |
2001-03-15 |
Bayer Ag |
Neuartige Aminodicarbonsäurederivate mit pharmazeutischen Eigenschaften
|
|
ES2316383T3
(es)
|
1999-09-17 |
2009-04-16 |
Millennium Pharmaceuticals, Inc. |
Benzamidas e inhibidores relacionados del factor xa.
|
|
CN1414966A
(zh)
|
1999-11-08 |
2003-04-30 |
麦克公司 |
用于制备咪唑烷酮αu蛋白拮抗剂的方法和中间体
|
|
EP1274700B1
(en)
|
2000-01-03 |
2004-11-17 |
Pharmacia Corporation |
Dihydrobenzopyrans, dihydrobenzothiopyrans, and tetrahydroquinolines for the treatment of cox-2-mediated disorders
|
|
JP2003522142A
(ja)
|
2000-02-08 |
2003-07-22 |
スミスクライン・ビーチャム・コーポレイション |
炎症性疾患の治療法および治療用組成物
|
|
NZ521028A
(en)
*
|
2000-03-16 |
2004-07-30 |
F |
Carboxylic acid derivatives as IP antagonists
|
|
AR031176A1
(es)
|
2000-11-22 |
2003-09-10 |
Bayer Ag |
Nuevos derivados de pirazolpiridina sustituidos con piridina
|
|
DE10110750A1
(de)
|
2001-03-07 |
2002-09-12 |
Bayer Ag |
Neuartige Aminodicarbonsäurederivate mit pharmazeutischen Eigenschaften
|
|
DE10110749A1
(de)
|
2001-03-07 |
2002-09-12 |
Bayer Ag |
Substituierte Aminodicarbonsäurederivate
|
|
TWI316055B
(enExample)
|
2001-04-26 |
2009-10-21 |
Nippon Shinyaku Co Ltd |
|
|
MY130622A
(en)
|
2001-11-05 |
2007-07-31 |
Novartis Ag |
Naphthyridine derivatives, their preparation and their use as phosphodiesterase isoenzyme 4 (pde4) inhibitors
|
|
TW200305423A
(en)
|
2002-02-14 |
2003-11-01 |
Ono Pharmaceutical Co |
N-carbamoyl nitrogen-containing condensed ring compound and medicament containing same as active ingredient
|
|
DE10220570A1
(de)
|
2002-05-08 |
2003-11-20 |
Bayer Ag |
Carbamat-substituierte Pyrazolopyridine
|
|
ES2201907B1
(es)
|
2002-05-29 |
2005-06-01 |
Almirall Prodesfarma, S.A. |
Nuevos derivados de indolilpiperidina como potentes agentes antihistaminicos y antialergicos.
|
|
SE0202483D0
(sv)
|
2002-08-21 |
2002-08-21 |
Astrazeneca Ab |
Chemical compounds
|
|
JP2006096662A
(ja)
|
2002-09-18 |
2006-04-13 |
Sumitomo Pharmaceut Co Ltd |
新規6−置換ウラシル誘導体及びアレルギー性疾患の治療剤
|
|
BR0314304A
(pt)
|
2002-09-18 |
2005-07-26 |
Ono Pharmaceutical Co |
Drogas e derivados de triazapiro[5.5]undecano compreendendo o mesmo como o ingrediente ativo
|
|
JP2004107299A
(ja)
|
2002-09-20 |
2004-04-08 |
Japan Energy Corp |
新規1−置換ウラシル誘導体及びアレルギー性疾患の治療剤
|
|
PE20040950A1
(es)
|
2003-02-14 |
2005-01-01 |
Theravance Inc |
DERIVADOS DE BIFENILO COMO AGONISTAS DE LOS RECEPTORES ADRENERGICOS ß2 Y COMO ANTAGONISTAS DE LOS RECEPTORES MUSCARINICOS
|
|
CA2514733A1
(en)
|
2003-02-28 |
2004-09-16 |
Transform Pharmaceuticals, Inc. |
Pharmaceutical co-crystal compositions of drugs such as carbamazepine, celecoxib, olanzapine, itraconazole, topiramate, modafinil, 5-fluorouracil, hydrochlorothiazide, acetaminophen, aspirin, flurbiprofen, phenytoin and ibuprofen
|
|
WO2004083207A1
(en)
|
2003-03-12 |
2004-09-30 |
Abbott Laboratories |
Naphthyridine derivatives as antibacterial agents
|
|
ATE372324T1
(de)
|
2003-04-30 |
2007-09-15 |
Inst For Pharm Discovery Inc |
Substituierte heteroarylverbindungen als inhibitoren von proteintyrosinphosphatasen
|
|
WO2005020926A2
(en)
|
2003-08-28 |
2005-03-10 |
Pharmacia Corporation |
Treatment or prevention of vascular disorders with cox-2 inhibitors in combination with cyclic amp-specific phosphodiesterase inhibitors
|
|
US7420059B2
(en)
|
2003-11-20 |
2008-09-02 |
Bristol-Myers Squibb Company |
HMG-CoA reductase inhibitors and method
|
|
DE602004025504D1
(de)
|
2003-12-23 |
2010-03-25 |
Novartis Ag |
Bicyclische heterocyclische p-38-kinase-inhibitoren
|
|
GB0413960D0
(en)
|
2004-06-22 |
2004-07-28 |
Novartis Ag |
Organic compounds
|
|
AR051780A1
(es)
|
2004-11-29 |
2007-02-07 |
Japan Tobacco Inc |
Compuestos en anillo fusionados que contienen nitrogeno y utilizacion de los mismos
|
|
EP2392328A1
(en)
|
2005-05-09 |
2011-12-07 |
Hydra Biosciences, Inc. |
Compounds for modulating TRPV3 Function
|
|
ES2270715B1
(es)
*
|
2005-07-29 |
2008-04-01 |
Laboratorios Almirall S.A. |
Nuevos derivados de pirazina.
|
|
ATE517883T1
(de)
|
2005-08-25 |
2011-08-15 |
Schering Corp |
Imidazolderivate als funktionelle selektive agonisten des alpha2c-adrenorezeptors
|
|
GB0601951D0
(en)
|
2006-01-31 |
2006-03-15 |
Novartis Ag |
Organic compounds
|
|
US7541371B2
(en)
|
2006-02-20 |
2009-06-02 |
Eisai R&D Management Co., Ltd. |
Method for treating a motor neuron disease
|
|
US20080305169A1
(en)
|
2006-05-26 |
2008-12-11 |
Japan Tobacco Inc. |
Pharmaceutical Compositions Comprising Nitrogen-Containing Fused Ring Coumpounds
|
|
US20080064871A1
(en)
|
2006-05-26 |
2008-03-13 |
Japan Tobacco Inc. |
Production Method of Nitrogen-Containing Fused Ring Compounds
|
|
US8163817B2
(en)
|
2007-05-11 |
2012-04-24 |
Canon Kabushiki Kaisha |
Aqueous ink, ink set, image forming method and image forming apparatus
|
|
US7928111B2
(en)
|
2007-06-08 |
2011-04-19 |
Senomyx, Inc. |
Compounds including substituted thienopyrimidinone derivatives as ligands for modulating chemosensory receptors
|
|
WO2009005672A1
(en)
*
|
2007-06-29 |
2009-01-08 |
Merck & Co., Inc. |
Antidiabetic azaindoles and diazaindoles
|
|
CN101952295B
(zh)
*
|
2008-02-25 |
2013-11-20 |
霍夫曼-拉罗奇有限公司 |
吡咯并吡嗪激酶抑制剂
|
|
EP2300425A4
(en)
*
|
2008-06-24 |
2012-03-21 |
Panmira Pharmaceuticals Llc |
PROSTAGLANDIN D2 RECEPTOR CYCLOALCANEÝBINDLUCK ANTAGONISTS
|
|
EP2324036B1
(en)
|
2008-07-16 |
2014-12-03 |
Merck Sharp & Dohme Corp. |
Bicyclic heterocycle derivatives and methods of use thereof
|
|
DE102008039082A1
(de)
|
2008-08-21 |
2010-02-25 |
Bayer Schering Pharma Aktiengesellschaft |
Azabicyclisch-substituierte 5-Aminopyrazole und ihre Verwendung
|
|
TWI368513B
(en)
*
|
2009-04-30 |
2012-07-21 |
Univ Kaohsiung Medical |
Synthesis of pulmodil and pulmodil-1, two chlorophenylpiperazine salt derivatives, and rhokinase-dependent inhibition activity on pulmonary artery endothelium dysfunction, medial wall thickness and vascular obstruction thereof
|
|
WO2011111880A1
(ko)
|
2010-03-08 |
2011-09-15 |
주식회사 메디젠텍 |
세포핵에서 세포질로의 gsk3의 이동을 억제하는 화합물을 함유하는 세포핵에서 세포질로의 gsk3 이동에 의해 발생되는 질환의 치료 또는 예방용 약학적 조성물
|
|
EP2585468A1
(en)
*
|
2010-06-23 |
2013-05-01 |
Vertex Pharmaceuticals Incorporated |
Pyrrolo- pyrazine derivatives useful as inhibitors of atr kinase
|
|
MA34373B1
(fr)
|
2010-07-14 |
2013-07-03 |
Novartis Ag |
Composés hétérocycliques agonistes du récepteur ip
|
|
JP6058698B2
(ja)
|
2012-01-13 |
2017-01-11 |
ノバルティス アーゲー |
Ip受容体アゴニストの塩
|
|
WO2013105061A1
(en)
|
2012-01-13 |
2013-07-18 |
Novartis Ag |
Fused dihydropyrido [2,3 -b] pyrazines as ip receptor agonists for the treatment of pulmonary arterial hypertension (pah) and related disorders
|
|
ES2565826T3
(es)
|
2012-01-13 |
2016-04-07 |
Novartis Ag |
Pirroles fusionados como agonistas del receptor IP para el tratamiento de hipertensión arterial pulmonar (PAH) y trastornos relacionados
|
|
US20140378463A1
(en)
|
2012-01-13 |
2014-12-25 |
Novartis Ag |
IP receptor agonist heterocyclic compounds
|
|
US20150005311A1
(en)
|
2012-01-13 |
2015-01-01 |
Novartis Ag |
IP receptor agonist heterocyclic compounds
|
|
WO2013105065A1
(en)
|
2012-01-13 |
2013-07-18 |
Novartis Ag |
Fused piperidines as ip receptor agonists for the treatment of pah and related disorders
|