|
GB1454864A
(en)
|
1974-03-05 |
1976-11-03 |
Wyeth John & Brother Ltd |
Thioureas
|
|
PT72878B
(en)
|
1980-04-24 |
1983-03-29 |
Merck & Co Inc |
Process for preparing mannich-base hydroxamic acid pro-drugs for the improved delivery of non-steroidal anti-inflammatory agents
|
|
DK0584222T3
(da)
|
1991-05-10 |
1998-02-23 |
Rhone Poulenc Rorer Int |
Bis-mono- og bicycliske aryl- og heteroarylforbindelser, som inhiberer EGF- og/eller PDGF-receptor-tyrosinkinase
|
|
CA2090283A1
(en)
|
1992-02-28 |
1993-08-29 |
Nobuyuki Hamanaka |
Phenoxyacetic acid derivatives
|
|
US5516652A
(en)
|
1993-10-06 |
1996-05-14 |
Merck Frosst Canada Inc. |
DNA encoding prostaglandin receptor IP
|
|
CN1145076A
(zh)
|
1994-02-10 |
1997-03-12 |
小野药品工业株式会社 |
前列腺素i2受体
|
|
WO1996035713A1
(en)
|
1995-05-08 |
1996-11-14 |
Pfizer, Inc. |
Dipeptides which promote release of growth hormone
|
|
GB9622386D0
(en)
|
1996-10-28 |
1997-01-08 |
Sandoz Ltd |
Organic compounds
|
|
TWI242011B
(en)
|
1997-03-31 |
2005-10-21 |
Eisai Co Ltd |
1,4-substituted cyclic amine derivatives
|
|
US6166037A
(en)
|
1997-08-28 |
2000-12-26 |
Merck & Co., Inc. |
Pyrrolidine and piperidine modulators of chemokine receptor activity
|
|
DE19834044A1
(de)
|
1998-07-29 |
2000-02-03 |
Bayer Ag |
Neue substituierte Pyrazolderivate
|
|
DE19834047A1
(de)
|
1998-07-29 |
2000-02-03 |
Bayer Ag |
Substituierte Pyrazolderivate
|
|
UA71586C2
(en)
|
1998-12-04 |
2004-12-15 |
Smithkline Beecham Corp |
A vitronectin receptor antagonist
|
|
GB9913083D0
(en)
|
1999-06-04 |
1999-08-04 |
Novartis Ag |
Organic compounds
|
|
IL145742A0
(en)
|
1999-05-04 |
2002-07-25 |
Schering Corp |
Piperidine derivatives useful as ccr5 antagonists
|
|
EP1632479B1
(en)
|
1999-05-04 |
2011-01-12 |
Schering Corporation |
Pharmaceutical compositions comprising CCR5 antagonizing piperazine derivatives
|
|
GB9914255D0
(en)
|
1999-06-18 |
1999-08-18 |
Lilly Forschung Gmbh |
Pharmaceutical compounds
|
|
EG24179A
(en)
|
1999-09-07 |
2008-09-28 |
Smithkline Beecham Corp |
Vitronectin receptor antagonists
|
|
DE19943635A1
(de)
|
1999-09-13 |
2001-03-15 |
Bayer Ag |
Neuartige Aminodicarbonsäurederivate mit pharmazeutischen Eigenschaften
|
|
DE19943634A1
(de)
|
1999-09-13 |
2001-04-12 |
Bayer Ag |
Neuartige Dicarbonsäurederivate mit pharmazeutischen Eigenschaften
|
|
DE19943639A1
(de)
|
1999-09-13 |
2001-03-15 |
Bayer Ag |
Dicarbonsäurederivate mit neuartigen pharmazeutischen Eigenschaften
|
|
DE19943636A1
(de)
|
1999-09-13 |
2001-03-15 |
Bayer Ag |
Neuartige Dicarbonsäurederivate mit pharmazeutischen Eigenschaften
|
|
JP4744050B2
(ja)
|
1999-09-17 |
2011-08-10 |
ミレニアム・ファーマシューティカルズ・インコーポレイテッド |
ベンズアミドおよび関連するXa因子阻害剤
|
|
CZ20021508A3
(cs)
|
1999-11-08 |
2002-10-16 |
Merck & Co., Inc. |
Způsob výroby imidazolidinonových derivátů
|
|
WO2001049675A1
(en)
|
2000-01-03 |
2001-07-12 |
Pharmacia Corporation |
Dihydrobenzopyrans, dihydrobenzothiopyrans, and tetrahydroquinolines for the treatment of cox-2-mediated disorders
|
|
BR0108087A
(pt)
|
2000-02-08 |
2002-10-29 |
Smithkline Beecham Corp |
Método e composições para o tratamento de uma doença inflamatória
|
|
KR100523119B1
(ko)
*
|
2000-03-16 |
2005-10-20 |
에프. 호프만-라 로슈 아게 |
Ip 길항제로서의 카복실산 유도체
|
|
AR031176A1
(es)
|
2000-11-22 |
2003-09-10 |
Bayer Ag |
Nuevos derivados de pirazolpiridina sustituidos con piridina
|
|
DE10110750A1
(de)
|
2001-03-07 |
2002-09-12 |
Bayer Ag |
Neuartige Aminodicarbonsäurederivate mit pharmazeutischen Eigenschaften
|
|
DE10110749A1
(de)
|
2001-03-07 |
2002-09-12 |
Bayer Ag |
Substituierte Aminodicarbonsäurederivate
|
|
TWI316055B
(enExample)
|
2001-04-26 |
2009-10-21 |
Nippon Shinyaku Co Ltd |
|
|
MY130622A
(en)
|
2001-11-05 |
2007-07-31 |
Novartis Ag |
Naphthyridine derivatives, their preparation and their use as phosphodiesterase isoenzyme 4 (pde4) inhibitors
|
|
TW200305423A
(en)
|
2002-02-14 |
2003-11-01 |
Ono Pharmaceutical Co |
N-carbamoyl nitrogen-containing condensed ring compound and medicament containing same as active ingredient
|
|
WO2004078163A2
(en)
|
2003-02-28 |
2004-09-16 |
Transform Pharmaceuticals, Inc. |
Pharmaceutical co-crystal compositions of drugs such as carbamazepine, celecoxib, olanzapine, itraconazole, topiramate, modafinil, 5-fluorouracil, hydrochlorothiazide, acetaminophen, aspirin, flurbiprofen, phenytoin and ibuprofen
|
|
DE10220570A1
(de)
|
2002-05-08 |
2003-11-20 |
Bayer Ag |
Carbamat-substituierte Pyrazolopyridine
|
|
ES2201907B1
(es)
|
2002-05-29 |
2005-06-01 |
Almirall Prodesfarma, S.A. |
Nuevos derivados de indolilpiperidina como potentes agentes antihistaminicos y antialergicos.
|
|
SE0202483D0
(sv)
|
2002-08-21 |
2002-08-21 |
Astrazeneca Ab |
Chemical compounds
|
|
TW200413372A
(en)
|
2002-09-18 |
2004-08-01 |
Ono Pharmaceutical Co |
Derivatives of triazaspiro [5.5] undecane and medicants using such derivatives as effective ingredient
|
|
JP2006096662A
(ja)
|
2002-09-18 |
2006-04-13 |
Sumitomo Pharmaceut Co Ltd |
新規6−置換ウラシル誘導体及びアレルギー性疾患の治療剤
|
|
JP2004107299A
(ja)
|
2002-09-20 |
2004-04-08 |
Japan Energy Corp |
新規1−置換ウラシル誘導体及びアレルギー性疾患の治療剤
|
|
PE20040950A1
(es)
|
2003-02-14 |
2005-01-01 |
Theravance Inc |
DERIVADOS DE BIFENILO COMO AGONISTAS DE LOS RECEPTORES ADRENERGICOS ß2 Y COMO ANTAGONISTAS DE LOS RECEPTORES MUSCARINICOS
|
|
WO2004083207A1
(en)
|
2003-03-12 |
2004-09-30 |
Abbott Laboratories |
Naphthyridine derivatives as antibacterial agents
|
|
CA2524221A1
(en)
|
2003-04-30 |
2004-11-18 |
The Institutes For Pharmaceutical Discovery, Llc |
Substituted heteroaryls as inhibitors of protein tyrosine phosphatases
|
|
WO2005020926A2
(en)
|
2003-08-28 |
2005-03-10 |
Pharmacia Corporation |
Treatment or prevention of vascular disorders with cox-2 inhibitors in combination with cyclic amp-specific phosphodiesterase inhibitors
|
|
US7420059B2
(en)
|
2003-11-20 |
2008-09-02 |
Bristol-Myers Squibb Company |
HMG-CoA reductase inhibitors and method
|
|
BRPI0418112A
(pt)
|
2003-12-23 |
2007-04-17 |
Novartis Ag |
inibidores de p-38 quinase bicìclico heterocìclicos
|
|
GB0413960D0
(en)
|
2004-06-22 |
2004-07-28 |
Novartis Ag |
Organic compounds
|
|
AR051780A1
(es)
|
2004-11-29 |
2007-02-07 |
Japan Tobacco Inc |
Compuestos en anillo fusionados que contienen nitrogeno y utilizacion de los mismos
|
|
WO2006122156A2
(en)
|
2005-05-09 |
2006-11-16 |
Hydra Biosciences, Inc. |
Compounds for modulating trpv3 function
|
|
ES2270715B1
(es)
*
|
2005-07-29 |
2008-04-01 |
Laboratorios Almirall S.A. |
Nuevos derivados de pirazina.
|
|
EP1945626B1
(en)
|
2005-08-25 |
2011-07-27 |
Schering Corporation |
Imidazole derivatives as functionally selective alpha2c adrenoreceptor agonists
|
|
GB0601951D0
(en)
|
2006-01-31 |
2006-03-15 |
Novartis Ag |
Organic compounds
|
|
US7541371B2
(en)
|
2006-02-20 |
2009-06-02 |
Eisai R&D Management Co., Ltd. |
Method for treating a motor neuron disease
|
|
US20080064871A1
(en)
|
2006-05-26 |
2008-03-13 |
Japan Tobacco Inc. |
Production Method of Nitrogen-Containing Fused Ring Compounds
|
|
US20080305169A1
(en)
|
2006-05-26 |
2008-12-11 |
Japan Tobacco Inc. |
Pharmaceutical Compositions Comprising Nitrogen-Containing Fused Ring Coumpounds
|
|
US8163817B2
(en)
|
2007-05-11 |
2012-04-24 |
Canon Kabushiki Kaisha |
Aqueous ink, ink set, image forming method and image forming apparatus
|
|
US7928111B2
(en)
|
2007-06-08 |
2011-04-19 |
Senomyx, Inc. |
Compounds including substituted thienopyrimidinone derivatives as ligands for modulating chemosensory receptors
|
|
WO2009005672A1
(en)
*
|
2007-06-29 |
2009-01-08 |
Merck & Co., Inc. |
Antidiabetic azaindoles and diazaindoles
|
|
JP5368484B2
(ja)
*
|
2008-02-25 |
2013-12-18 |
エフ.ホフマン−ラ ロシュ アーゲー |
ピロロピラジンキナーゼ阻害剤
|
|
EP2300425A4
(en)
*
|
2008-06-24 |
2012-03-21 |
Panmira Pharmaceuticals Llc |
PROSTAGLANDIN D2 RECEPTOR CYCLOALCANEÝBINDLUCK ANTAGONISTS
|
|
JP2011528369A
(ja)
|
2008-07-16 |
2011-11-17 |
シェーリング コーポレイション |
二環式ヘテロ環誘導体およびそれらの使用方法
|
|
DE102008039082A1
(de)
|
2008-08-21 |
2010-02-25 |
Bayer Schering Pharma Aktiengesellschaft |
Azabicyclisch-substituierte 5-Aminopyrazole und ihre Verwendung
|
|
TWI368513B
(en)
*
|
2009-04-30 |
2012-07-21 |
Univ Kaohsiung Medical |
Synthesis of pulmodil and pulmodil-1, two chlorophenylpiperazine salt derivatives, and rhokinase-dependent inhibition activity on pulmonary artery endothelium dysfunction, medial wall thickness and vascular obstruction thereof
|
|
WO2011111880A1
(ko)
|
2010-03-08 |
2011-09-15 |
주식회사 메디젠텍 |
세포핵에서 세포질로의 gsk3의 이동을 억제하는 화합물을 함유하는 세포핵에서 세포질로의 gsk3 이동에 의해 발생되는 질환의 치료 또는 예방용 약학적 조성물
|
|
NZ605627A
(en)
*
|
2010-06-23 |
2015-06-26 |
Vertex Pharma |
Pyrrolo-pyrazine derivatives useful as inhibitors of atr kinase
|
|
KR101491938B1
(ko)
|
2010-07-14 |
2015-02-10 |
노파르티스 아게 |
Ip 수용체 효능제 헤테로시클릭 화합물
|
|
WO2013105058A1
(en)
|
2012-01-13 |
2013-07-18 |
Novartis Ag |
7,8- dihydropyrido [3, 4 - b] pyrazines as ip receptor agonists for the treatment of pulmonary arterial hypertension (pah) and related disorders
|
|
UY34572A
(es)
|
2012-01-13 |
2013-09-02 |
Novartis Ag |
Compuestos heterocíclicos agonistas del receptor ip
|
|
US9174985B2
(en)
|
2012-01-13 |
2015-11-03 |
Novartis Ag |
Salts of 7-(2,3-di-p-tolyl-7,8-dihydropyrido[2,3-b]pyrazin-5(6H)-yl)heptanoic acid as IP receptor agonists
|
|
US9115129B2
(en)
|
2012-01-13 |
2015-08-25 |
Novartis Ag |
Substituted pyrido[2,3-B]pyrazines as IP receptor agonists
|
|
WO2013105063A1
(en)
|
2012-01-13 |
2013-07-18 |
Novartis Ag |
Fused piperidines as ip receptor agonists for the treatment of pulmonary arterial hypertension (pah) and related disorders
|
|
WO2013105061A1
(en)
|
2012-01-13 |
2013-07-18 |
Novartis Ag |
Fused dihydropyrido [2,3 -b] pyrazines as ip receptor agonists for the treatment of pulmonary arterial hypertension (pah) and related disorders
|