|
DK1583562T3
(da)
|
2003-01-06 |
2011-09-19 |
Angiochem Inc |
Angiopep-1, beslægtede forbindelser og anvendelser deraf
|
|
EP1912679A4
(en)
*
|
2005-06-15 |
2009-07-29 |
Massachusetts Inst Technology |
AMINOUS LIPIDS AND ITS USES
|
|
US9365634B2
(en)
|
2007-05-29 |
2016-06-14 |
Angiochem Inc. |
Aprotinin-like polypeptides for delivering agents conjugated thereto to tissues
|
|
AU2009238187B2
(en)
|
2008-04-18 |
2014-03-06 |
Angiochem Inc. |
Pharmaceutical compositions of paclitaxel, paclitaxel analogs or paclitaxel conjugates and related methods of preparation and use
|
|
CA2740317A1
(en)
|
2008-10-15 |
2010-04-22 |
Angiochem Inc. |
Etoposide and doxorubicin conjugates for drug delivery
|
|
CA2740316A1
(en)
|
2008-10-15 |
2010-04-22 |
Angiochem Inc. |
Conjugates of glp-1 agonists and uses thereof
|
|
WO2010053572A2
(en)
|
2008-11-07 |
2010-05-14 |
Massachusetts Institute Of Technology |
Aminoalcohol lipidoids and uses thereof
|
|
CA2745524C
(en)
|
2008-12-05 |
2020-06-09 |
Angiochem Inc. |
Conjugates of neurotensin or neurotensin analogs and uses thereof
|
|
BRPI0922611A2
(pt)
|
2008-12-17 |
2018-11-06 |
Angiochem Inc |
inibidores de metaloproteína de matriz de membrana tipo 1 e usos dos mesmos
|
|
US9173891B2
(en)
|
2009-04-20 |
2015-11-03 |
Angiochem, Inc. |
Treatment of ovarian cancer using an anticancer agent conjugated to an angiopep-2 analog
|
|
EP2448965A4
(en)
|
2009-07-02 |
2015-02-11 |
Angiochem Inc |
MULTIMEPEPTID CONJUGATES AND ITS USES
|
|
RS58405B1
(sr)
|
2009-12-01 |
2019-04-30 |
Translate Bio Inc |
Stereoidni derivati za isporuku irnk u humanim genetskim oboljenjima
|
|
US8822663B2
(en)
|
2010-08-06 |
2014-09-02 |
Moderna Therapeutics, Inc. |
Engineered nucleic acids and methods of use thereof
|
|
US9193827B2
(en)
|
2010-08-26 |
2015-11-24 |
Massachusetts Institute Of Technology |
Poly(beta-amino alcohols), their preparation, and uses thereof
|
|
CA2821992A1
(en)
|
2010-10-01 |
2012-04-05 |
Moderna Therapeutics, Inc. |
Engineered nucleic acids and methods of use thereof
|
|
CA2831392C
(en)
|
2011-03-28 |
2020-04-28 |
Massachusetts Institute Of Technology |
Conjugated lipomers and uses thereof
|
|
DE12722942T1
(de)
|
2011-03-31 |
2021-09-30 |
Modernatx, Inc. |
Freisetzung und formulierung von manipulierten nukleinsäuren
|
|
ES2987057T3
(es)
|
2011-06-08 |
2024-11-13 |
Translate Bio Inc |
Lípidos escindibles
|
|
JP6184945B2
(ja)
|
2011-06-08 |
2017-08-23 |
シャイアー ヒューマン ジェネティック セラピーズ インコーポレイテッド |
mRNA送達のための脂質ナノ粒子組成物および方法
|
|
US9464124B2
(en)
|
2011-09-12 |
2016-10-11 |
Moderna Therapeutics, Inc. |
Engineered nucleic acids and methods of use thereof
|
|
HRP20220250T1
(hr)
|
2011-10-03 |
2022-04-29 |
Modernatx, Inc. |
Modificirani nukleozidi, nukleotidi i nukleinske kiseline, te njihove uporabe
|
|
PE20181541A1
(es)
|
2011-10-27 |
2018-09-26 |
Massachusetts Inst Technology |
Derivados de aminoacidos funcionalizados en la terminal n capaces de formar microesferas encapsuladoras de farmaco
|
|
SI2791160T1
(sl)
|
2011-12-16 |
2022-07-29 |
Modernatx, Inc. |
Sestave modificirane MRNA
|
|
US9572897B2
(en)
|
2012-04-02 |
2017-02-21 |
Modernatx, Inc. |
Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins
|
|
AU2013243952A1
(en)
|
2012-04-02 |
2014-10-30 |
Modernatx, Inc. |
Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins
|
|
US10501512B2
(en)
|
2012-04-02 |
2019-12-10 |
Modernatx, Inc. |
Modified polynucleotides
|
|
US9283287B2
(en)
|
2012-04-02 |
2016-03-15 |
Moderna Therapeutics, Inc. |
Modified polynucleotides for the production of nuclear proteins
|
|
US20150267192A1
(en)
|
2012-06-08 |
2015-09-24 |
Shire Human Genetic Therapies, Inc. |
Nuclease resistant polynucleotides and uses thereof
|
|
WO2014028487A1
(en)
|
2012-08-13 |
2014-02-20 |
Massachusetts Institute Of Technology |
Amine-containing lipidoids and uses thereof
|
|
SMT202200337T1
(it)
|
2012-11-26 |
2022-09-14 |
Modernatx Inc |
Rna modificato al livello del terminale
|
|
EP3932947A1
(en)
|
2013-03-14 |
2022-01-05 |
Translate Bio MA, Inc. |
Methods and compositions for delivering mrna coded antibodies
|
|
EP2970955B1
(en)
|
2013-03-14 |
2018-11-14 |
Translate Bio, Inc. |
Methods for purification of messenger rna
|
|
EP2971010B1
(en)
|
2013-03-14 |
2020-06-10 |
ModernaTX, Inc. |
Formulation and delivery of modified nucleoside, nucleotide, and nucleic acid compositions
|
|
WO2014153052A2
(en)
|
2013-03-14 |
2014-09-25 |
Shire Human Genetic Therapies, Inc. |
Cftr mrna compositions and related methods and uses
|
|
US8980864B2
(en)
|
2013-03-15 |
2015-03-17 |
Moderna Therapeutics, Inc. |
Compositions and methods of altering cholesterol levels
|
|
US10077439B2
(en)
|
2013-03-15 |
2018-09-18 |
Modernatx, Inc. |
Removal of DNA fragments in mRNA production process
|
|
US9315472B2
(en)
|
2013-05-01 |
2016-04-19 |
Massachusetts Institute Of Technology |
1,3,5-triazinane-2,4,6-trione derivatives and uses thereof
|
|
EP3041938A1
(en)
|
2013-09-03 |
2016-07-13 |
Moderna Therapeutics, Inc. |
Circular polynucleotides
|
|
AU2014315287A1
(en)
|
2013-09-03 |
2015-03-12 |
Moderna Therapeutics, Inc. |
Chimeric polynucleotides
|
|
US10023626B2
(en)
|
2013-09-30 |
2018-07-17 |
Modernatx, Inc. |
Polynucleotides encoding immune modulating polypeptides
|
|
US10323076B2
(en)
|
2013-10-03 |
2019-06-18 |
Modernatx, Inc. |
Polynucleotides encoding low density lipoprotein receptor
|
|
CN112656954A
(zh)
*
|
2013-10-22 |
2021-04-16 |
夏尔人类遗传性治疗公司 |
用于递送信使rna的脂质制剂
|
|
MX2016005239A
(es)
|
2013-10-22 |
2016-08-12 |
Shire Human Genetic Therapies |
Tratamiento con acido ribonucleico mensajero para la fenilcetonuria.
|
|
BR112016009014B1
(pt)
*
|
2013-10-22 |
2024-02-06 |
Translate Bio, Inc |
USO DE COMPOSIÇÃO COMPREENDENDO mRNA PARA DEFICIÊNCIA DE ARGININOSSUCINATO SINTETASE
|
|
BR112016008832A2
(pt)
*
|
2013-10-22 |
2017-10-03 |
Shire Human Genetic Therapies |
Distribuição de mrna no snc e suas utilizações
|
|
SI3116900T1
(sl)
|
2014-03-09 |
2021-02-26 |
The Trustees Of The University Of Pennsylvania |
Sestavki uporabni pri zdravljenju pomanjkanja ornitin transkarbamilaze(OTC)
|
|
JP6372118B2
(ja)
*
|
2014-03-18 |
2018-08-15 |
東洋インキScホールディングス株式会社 |
両性界面活性剤とその製造方法
|
|
RS58337B1
(sr)
|
2014-03-24 |
2019-03-29 |
Translate Bio Inc |
Irnk terapija za lečenje očnih oboljenja
|
|
SG10201912038TA
(en)
|
2014-04-23 |
2020-02-27 |
Modernatx Inc |
Nucleic acid vaccines
|
|
SG11201608725YA
(en)
|
2014-04-25 |
2016-11-29 |
Shire Human Genetic Therapies |
Methods for purification of messenger rna
|
|
EP3587409B8
(en)
*
|
2014-05-30 |
2022-07-13 |
Translate Bio, Inc. |
Biodegradable lipids for delivery of nucleic acids
|
|
CA2951707A1
(en)
*
|
2014-06-10 |
2015-12-17 |
Massachusetts Institute Of Technology |
Method for gene editing
|
|
KR102511554B1
(ko)
*
|
2014-06-24 |
2023-03-16 |
샤이어 휴먼 지네틱 테라피즈 인크. |
핵산의 전달용 입체화학적으로 풍부한 조성물
|
|
CA2953265C
(en)
|
2014-07-02 |
2023-09-26 |
Shire Human Genetic Therapies, Inc. |
Encapsulation of messenger rna
|
|
WO2016004202A1
(en)
|
2014-07-02 |
2016-01-07 |
Massachusetts Institute Of Technology |
Polyamine-fatty acid derived lipidoids and uses thereof
|
|
WO2016011226A1
(en)
|
2014-07-16 |
2016-01-21 |
Moderna Therapeutics, Inc. |
Chimeric polynucleotides
|
|
WO2016014846A1
(en)
|
2014-07-23 |
2016-01-28 |
Moderna Therapeutics, Inc. |
Modified polynucleotides for the production of intrabodies
|
|
WO2016025643A1
(en)
|
2014-08-12 |
2016-02-18 |
Massachusetts Institute Of Technology |
Brush-poly(glycoamidoamine)-lipids and uses thereof
|
|
US9943595B2
(en)
|
2014-12-05 |
2018-04-17 |
Translate Bio, Inc. |
Messenger RNA therapy for treatment of articular disease
|
|
EP3900702A1
(en)
*
|
2015-03-19 |
2021-10-27 |
Translate Bio, Inc. |
Mrna therapy for pompe disease
|
|
WO2016187531A1
(en)
*
|
2015-05-21 |
2016-11-24 |
Ohio State Innovation Foundation |
Benzene-1,3,5-tricarboxamide derivatives and uses thereof
|
|
DK3307326T3
(da)
|
2015-06-15 |
2020-10-19 |
Angiochem Inc |
Fremgangsmåder til behandling af leptomeningeal karcinomatose
|
|
LT3310764T
(lt)
*
|
2015-06-19 |
2023-06-12 |
Massachusetts Institute Of Technology |
Alkenilu pakeisti 2,5-piperazindionai ir jų panaudojimas kompozicijose, skirtose agento pristatymui į subjektą ar ląstelę
|
|
WO2017031232A1
(en)
|
2015-08-17 |
2017-02-23 |
Modernatx, Inc. |
Methods for preparing particles and related compositions
|
|
EA201890999A1
(ru)
|
2015-10-22 |
2018-12-28 |
МОДЕРНАТиЭкс, ИНК. |
Вакцина против вируса простого герпеса
|
|
EA201891001A1
(ru)
|
2015-10-22 |
2018-11-30 |
МОДЕРНАТиЭкс, ИНК. |
Вакцины на основе нуклеиновых кислот против вируса ветряной оспы (vzv)
|
|
EP4349405A3
(en)
|
2015-10-22 |
2024-06-19 |
ModernaTX, Inc. |
Respiratory virus vaccines
|
|
CN109310751A
(zh)
|
2015-10-22 |
2019-02-05 |
摩登纳特斯有限公司 |
广谱流感病毒疫苗
|
|
AU2016341311B2
(en)
|
2015-10-22 |
2023-11-16 |
Modernatx, Inc. |
Respiratory syncytial virus vaccine
|
|
WO2017070613A1
(en)
*
|
2015-10-22 |
2017-04-27 |
Modernatx, Inc. |
Human cytomegalovirus vaccine
|
|
PL3394093T3
(pl)
|
2015-12-23 |
2022-05-16 |
Modernatx, Inc. |
Metody stosowania polinukleotydów kodujących ligand ox40
|
|
EP3400023A1
(en)
|
2016-01-10 |
2018-11-14 |
ModernaTX, Inc. |
Therapeutic mrnas encoding anti ctla-4 antibodies
|
|
EP3825400B1
(en)
|
2016-04-08 |
2024-12-25 |
Translate Bio, Inc. |
Multimeric coding nucleic acid and uses thereof
|
|
AU2017268394A1
(en)
|
2016-05-18 |
2019-01-03 |
Modernatx, Inc. |
Polynucleotides encoding relaxin
|
|
CN109563144B
(zh)
|
2016-06-01 |
2023-03-28 |
雅斯娜 |
化合物
|
|
CA3027312A1
(en)
|
2016-06-13 |
2017-12-21 |
Translate Bio, Inc. |
Messenger rna therapy for the treatment of ornithine transcarbamylase deficiency
|
|
RU2762607C2
(ru)
|
2016-09-13 |
2021-12-21 |
Аллерган, Инк. |
Стабилизированные небелковые композиции клостридиального токсина
|
|
MA46584A
(fr)
|
2016-10-21 |
2019-08-28 |
Modernatx Inc |
Vaccin contre le cytomégalovirus humain
|
|
US12491261B2
(en)
|
2016-10-26 |
2025-12-09 |
Acuitas Therapeutics, Inc. |
Lipid nanoparticle formulations
|
|
WO2018089801A1
(en)
|
2016-11-10 |
2018-05-17 |
Translate Bio, Inc. |
Improved process of preparing mrna-loaded lipid nanoparticles
|
|
CA3041350A1
(en)
|
2016-11-10 |
2018-05-17 |
Translate Bio, Inc. |
Subcutaneous delivery of messenger rna
|
|
JP2020501545A
(ja)
|
2016-12-08 |
2020-01-23 |
キュアバック アーゲー |
肝疾患の処置または予防のためのrna
|
|
US11542490B2
(en)
|
2016-12-08 |
2023-01-03 |
CureVac SE |
RNAs for wound healing
|
|
IL268857B2
(en)
|
2017-02-27 |
2024-09-01 |
Translate Bio Inc |
Methods for purification of messenger rna
|
|
US10975369B2
(en)
|
2017-02-27 |
2021-04-13 |
Translate Bio, Inc. |
Methods for purification of messenger RNA
|
|
AU2018224326B2
(en)
|
2017-02-27 |
2024-01-04 |
Translate Bio, Inc. |
Novel codon-optimized CFTR mRNA
|
|
US10961184B2
(en)
|
2017-03-07 |
2021-03-30 |
Translate Bio, Inc. |
Polyanionic delivery of nucleic acids
|
|
WO2018170270A1
(en)
*
|
2017-03-15 |
2018-09-20 |
Modernatx, Inc. |
Varicella zoster virus (vzv) vaccine
|
|
EP3607074A4
(en)
|
2017-04-05 |
2021-07-07 |
Modernatx, Inc. |
REDUCTION OR ELIMINATION OF IMMUNE RESPONSES TO NON-INTRAVENOUS THERAPEUTIC PROTEINS, FOR EXAMPLE SUBCUTANEOUSLY
|
|
ES2981244T3
(es)
|
2017-04-28 |
2024-10-07 |
Acuitas Therapeutics Inc |
Novedosas formulaciones de nanopartículas de lípidos de carbonilo y lípidos para la administración de ácidos nucleicos
|
|
JOP20190260A1
(ar)
|
2017-05-02 |
2019-10-31 |
Merck Sharp & Dohme |
صيغ ثابتة لأجسام مضادة لمستقبل الموت المبرمج 1 (pd-1) وطرق استخدامها
|
|
WO2018204374A1
(en)
|
2017-05-02 |
2018-11-08 |
Merck Sharp & Dohme Corp. |
Formulations of anti-lag3 antibodies and co-formulations of anti-lag3 antibodies and anti-pd-1 antibodies
|
|
IL270631B2
(en)
|
2017-05-16 |
2024-03-01 |
Translate Bio Inc |
Treatment of cystic fibrosis through the administration of mRNA with an optimal codon encoding ctfr
|
|
WO2018232357A1
(en)
|
2017-06-15 |
2018-12-20 |
Modernatx, Inc. |
Rna formulations
|
|
US10780183B2
(en)
|
2017-06-19 |
2020-09-22 |
Translate Bio, Inc. |
Messenger RNA therapy for the treatment of Friedreich's ataxia
|
|
JP7355731B2
(ja)
|
2017-08-16 |
2023-10-03 |
アクイタス セラピューティクス インコーポレイテッド |
脂質ナノ粒子製剤における使用のための脂質
|
|
US12065396B2
(en)
|
2017-08-17 |
2024-08-20 |
Acuitas Therapeutics, Inc. |
Lipids for use in lipid nanoparticle formulations
|
|
WO2019036028A1
(en)
|
2017-08-17 |
2019-02-21 |
Acuitas Therapeutics, Inc. |
LIPIDS FOR USE IN LIPID NANOPARTICULAR FORMULATIONS
|
|
US11524932B2
(en)
|
2017-08-17 |
2022-12-13 |
Acuitas Therapeutics, Inc. |
Lipids for use in lipid nanoparticle formulations
|
|
US11744801B2
(en)
|
2017-08-31 |
2023-09-05 |
Modernatx, Inc. |
Methods of making lipid nanoparticles
|
|
EP4092038A1
(en)
|
2017-09-11 |
2022-11-23 |
Protagonist Therapeutics, Inc. |
Opioid agonist peptides and uses thereof
|
|
EP3461487A1
(en)
*
|
2017-09-29 |
2019-04-03 |
Nlife Therapeutics S.L. |
Compositions and methods for the delivery of mrna to hepatic cells
|
|
WO2019079386A1
(en)
*
|
2017-10-17 |
2019-04-25 |
Sarepta Therapeutics, Inc. |
CELL PENETRATION PEPTIDES FOR ANTISENSE ADMINISTRATION
|
|
EP3700537A4
(en)
*
|
2017-10-17 |
2021-08-04 |
Sarepta Therapeutics, Inc. |
BICYCLIC PEPTIDE-OLIGONUCLEOTIDE CONJUGATES
|
|
CN111386105B
(zh)
*
|
2017-11-06 |
2023-09-15 |
日东电工株式会社 |
用于递送生物活性分子的膜融合化合物
|
|
JP7360716B2
(ja)
|
2017-12-01 |
2023-10-13 |
スーチョウ リボ ライフ サイエンス カンパニー、リミテッド |
核酸、当該核酸を含む組成物および複合体ならびに調製方法と使用
|
|
EP3719128B1
(en)
|
2017-12-01 |
2025-01-15 |
Suzhou Ribo Life Science Co., Ltd. |
Double-stranded oligonucleotide, composition and conjugate comprising double-stranded oligonucleotide, preparation method therefor and use thereof
|
|
CN118291456A
(zh)
|
2017-12-01 |
2024-07-05 |
苏州瑞博生物技术股份有限公司 |
一种核酸、含有该核酸的组合物与缀合物及制备方法和用途
|
|
EP3718572B1
(en)
|
2017-12-01 |
2024-07-31 |
Suzhou Ribo Life Science Co., Ltd. |
Nucleic acid, composition and conjugate containing nucleic acid, preparation method and use
|
|
JP7261494B2
(ja)
|
2017-12-01 |
2023-04-20 |
スーチョウ リボ ライフ サイエンス カンパニー、リミテッド |
核酸、当該核酸を含む組成物及び複合体ならびに調製方法と使用
|
|
EP3727428A1
(en)
|
2017-12-20 |
2020-10-28 |
Translate Bio, Inc. |
Improved composition and methods for treatment of ornithine transcarbamylase deficiency
|
|
KR102128951B1
(ko)
*
|
2017-12-21 |
2020-07-01 |
탑월드(주) |
비즈왁스와 동식물성 오일을 함유하는 화장료 조성물
|
|
JP7436030B2
(ja)
|
2017-12-29 |
2024-02-21 |
スーチョウ リボ ライフ サイエンス カンパニー、リミテッド |
複合体及びその調製方法と使用
|
|
WO2019152802A1
(en)
|
2018-02-02 |
2019-08-08 |
Translate Bio, Inc. |
Cationic polymers
|
|
CN108467475B
(zh)
*
|
2018-03-08 |
2020-02-14 |
山西大学 |
一种环状聚合物及其制备方法和应用
|
|
WO2019178479A1
(en)
*
|
2018-03-16 |
2019-09-19 |
Sarepta Therapeutics, Inc. |
Chimeric peptides for antisense delivery
|
|
US20210220449A1
(en)
|
2018-05-15 |
2021-07-22 |
Translate Bio, Inc. |
Subcutaneous Delivery of Messenger RNA
|
|
MA52625A
(fr)
|
2018-05-16 |
2021-03-24 |
Translate Bio Inc |
Lipides cationiques de ribose
|
|
US12076439B2
(en)
|
2018-05-24 |
2024-09-03 |
Translate Bio, Inc. |
Thioester cationic lipids
|
|
CA3101484A1
(en)
|
2018-05-30 |
2019-12-05 |
Translate Bio, Inc. |
Phosphoester cationic lipids
|
|
SG11202011587PA
(en)
|
2018-05-30 |
2020-12-30 |
Translate Bio Inc |
Messenger rna vaccines and uses thereof
|
|
US11547666B2
(en)
|
2018-05-30 |
2023-01-10 |
Translate Bio, Inc. |
Cationic lipids comprising a steroidal moiety
|
|
MA52766A
(fr)
|
2018-05-30 |
2021-04-14 |
Translate Bio Inc |
Lipides cationiques vitaminiques
|
|
CN108727209A
(zh)
*
|
2018-06-20 |
2018-11-02 |
复旦大学 |
具有n,n-二烷基亮氨酸结构的化合物及其制备方法
|
|
US11814445B2
(en)
|
2018-06-21 |
2023-11-14 |
Ra Pharmaceuticals, Inc. |
Cyclic polypeptides for PCSK9 inhibition
|
|
EP3810196A4
(en)
|
2018-06-21 |
2022-05-04 |
Merck Sharp & Dohme Corp. |
CYCLIC POLYPEPTIDES FOR PCSK9 INHIBITION
|
|
US11306125B2
(en)
|
2018-06-21 |
2022-04-19 |
Merck Sharp & Dohme Corp. |
PCSK9 antagonists bicyclo-compounds
|
|
JOP20190150A1
(ar)
|
2018-06-21 |
2019-12-21 |
Merck Sharp & Dohme |
مركبات مناهضة لـ pcsk9
|
|
EP3810178A4
(en)
|
2018-06-21 |
2022-05-04 |
Merck Sharp & Dohme Corp. |
CYCLIC POLYPEPTIDES TO INHIBIT PCSK9
|
|
ES3013570T3
(en)
|
2018-06-21 |
2025-04-14 |
Ucb Holdings Inc |
Cyclic polypeptides for pcsk9 inhibition
|
|
US20210378977A1
(en)
|
2018-07-23 |
2021-12-09 |
Translate Bio, Inc. |
Dry Powder Formulations for Messenger RNA
|
|
EP3833762A4
(en)
|
2018-08-09 |
2022-09-28 |
Verseau Therapeutics, Inc. |
Oligonucleotide compositions for targeting ccr2 and csf1r and uses thereof
|
|
WO2020038377A1
(zh)
|
2018-08-21 |
2020-02-27 |
苏州瑞博生物技术有限公司 |
一种核酸、含有该核酸的药物组合物和缀合物及其用途
|
|
CN112930396B
(zh)
|
2018-08-24 |
2024-05-24 |
川斯勒佰尔公司 |
用于纯化信使rna的方法
|
|
CN112839639A
(zh)
|
2018-08-29 |
2021-05-25 |
川斯勒佰尔公司 |
制备负载mRNA的脂质纳米颗粒的改进方法
|
|
SG11202102058UA
(en)
|
2018-08-30 |
2021-03-30 |
Tenaya Therapeutics Inc |
Cardiac cell reprogramming with myocardin and ascl1
|
|
US20230145188A1
(en)
|
2018-09-14 |
2023-05-11 |
Translate Bio, Inc. |
Composition and methods for treatment of methylmalonic acidemia
|
|
WO2020061457A1
(en)
|
2018-09-20 |
2020-03-26 |
Modernatx, Inc. |
Preparation of lipid nanoparticles and methods of administration thereof
|
|
IL281615B1
(en)
|
2018-09-21 |
2025-09-01 |
Acuitas Therapeutics Inc |
Systems and methods for producing lipid nanoparticles and liposomes
|
|
US11896674B2
(en)
|
2018-09-30 |
2024-02-13 |
Suzhou Ribo Life Science Co., Ltd. |
SiRNA conjugate, preparation method therefor and use thereof
|
|
CN112888451A
(zh)
|
2018-10-19 |
2021-06-01 |
川斯勒佰尔公司 |
信使rna的无泵包封
|
|
KR20210089215A
(ko)
|
2018-11-07 |
2021-07-15 |
머크 샤프 앤드 돔 코포레이션 |
항-lag3 항체 및 항-pd-1 항체의 공동-제제
|
|
CA3115119A1
(en)
|
2018-11-08 |
2020-05-14 |
Translate Bio, Inc. |
Methods and compositions for messenger rna purification
|
|
US20220016029A1
(en)
|
2018-11-09 |
2022-01-20 |
Translate Bio, Inc. |
Multi-peg lipid compounds
|
|
US12280147B2
(en)
|
2018-11-09 |
2025-04-22 |
Translate Bio, Inc. |
PEG lipidoid compounds
|
|
CA3117882A1
(en)
*
|
2018-11-09 |
2020-05-14 |
Translate Bio, Inc. |
2,5-dioxopiperazine lipids with intercalated ester, thioester, disulfide and anhydride moieities
|
|
US20220016265A1
(en)
|
2018-11-09 |
2022-01-20 |
Translate Bio, Inc. |
Messenger rna therapy for treatment of ocular diseases
|
|
WO2020102172A2
(en)
|
2018-11-12 |
2020-05-22 |
Translate Bio, Inc. |
Methods for inducing immune tolerance
|
|
ES2971849T3
(es)
|
2018-11-21 |
2024-06-10 |
Translate Bio Inc |
Compuestos lipídicos catiónicos y composiciones de los mismos para su uso en la administración de ARN mensajero
|
|
US20200157157A1
(en)
|
2018-11-21 |
2020-05-21 |
Translate Bio, Inc. |
TREATMENT OF CYSTIC FIBROSIS BY DELIVERY OF NEBULIZED mRNA ENCODING CFTR
|
|
US20220040281A1
(en)
|
2018-12-21 |
2022-02-10 |
Curevac Ag |
Rna for malaria vaccines
|
|
JP7507495B2
(ja)
|
2018-12-28 |
2024-06-28 |
スーチョウ リボ ライフ サイエンス カンパニー、リミテッド |
核酸、当該核酸を含む組成物及び複合体ならびに調製方法と使用
|
|
CA3125588A1
(en)
|
2019-01-07 |
2020-07-16 |
Translate Bio, Inc. |
Composition and methods for treatment of primary ciliary dyskinesia
|
|
EP3920950A1
(en)
|
2019-02-08 |
2021-12-15 |
CureVac AG |
Coding rna administered into the suprachoroidal space in the treatment of ophtalmic diseases
|
|
US20220177423A1
(en)
|
2019-04-18 |
2022-06-09 |
Translate Bio, Inc. |
Cystine cationic lipids
|
|
ES2972014T3
(es)
|
2019-04-22 |
2024-06-10 |
Translate Bio Inc |
Lípidos catiónicos de tioéster
|
|
US12453759B2
(en)
|
2019-05-03 |
2025-10-28 |
Translate Bio, Inc. |
Di-thioester cationic lipids
|
|
BR112021022909A2
(pt)
|
2019-05-14 |
2022-01-25 |
Translate Bio Inc |
Processo aprimorado de preparação de nanopartículas lipídicas carregadas com mrna
|
|
CN118256498A
(zh)
|
2019-05-22 |
2024-06-28 |
苏州瑞博生物技术股份有限公司 |
核酸、药物组合物与缀合物及制备方法和用途
|
|
US20220226244A1
(en)
|
2019-05-31 |
2022-07-21 |
Translate Bio, Inc. |
Macrocyclic lipids
|
|
WO2020254535A1
(en)
|
2019-06-18 |
2020-12-24 |
Curevac Ag |
Rotavirus mrna vaccine
|
|
CN114401942B
(zh)
|
2019-06-21 |
2024-01-26 |
川斯勒佰尔公司 |
三(羟甲基)甲基甘氨酸和柠檬酸脂质
|
|
WO2020257611A1
(en)
|
2019-06-21 |
2020-12-24 |
Translate Bio, Inc. |
Cationic lipids comprising an hydroxy moiety
|
|
KR20220078557A
(ko)
|
2019-07-08 |
2022-06-10 |
트랜슬레이트 바이오 인코포레이티드 |
개선된 mrna 로딩된 지질 나노입자 및 이의 제조 방법
|
|
EP3997226A1
(en)
|
2019-07-11 |
2022-05-18 |
Tenaya Therapeutics, Inc. |
Cardiac cell reprogramming with micrornas and other factors
|
|
WO2021016430A1
(en)
|
2019-07-23 |
2021-01-28 |
Translate Bio, Inc. |
Stable compositions of mrna-loaded lipid nanoparticles and processes of making
|
|
US20220323542A1
(en)
|
2019-07-30 |
2022-10-13 |
Translate Bio, Inc. |
TREATMENT OF CYSTIC FIBROSIS BY DELIVERY OF NEBULIZED mRNA ENCODING CFTR
|
|
CA3144902A1
(en)
|
2019-08-14 |
2022-01-19 |
Andreas Thess |
Rna combinations and compositions with decreased immunostimulatory properties
|
|
EP4021919A1
(en)
|
2019-08-30 |
2022-07-06 |
Merck Sharp & Dohme Corp. |
Pcsk9 antagonist compounds
|
|
MX2022003394A
(es)
|
2019-09-20 |
2022-06-22 |
Translate Bio Inc |
Arnm que codifica cftr manipulado.
|
|
AU2020355000A1
(en)
|
2019-09-23 |
2022-03-17 |
Omega Therapeutics, Inc. |
Compositions and methods for modulating apolipoprotein B (APOB) gene expression
|
|
JP2022548399A
(ja)
|
2019-09-23 |
2022-11-18 |
オメガ セラピューティクス, インコーポレイテッド |
肝細胞核因子4-アルファ(HNF4α)遺伝子発現をモジュレートするための組成物および方法
|
|
EP4529928A3
(en)
|
2019-10-09 |
2025-05-28 |
Translate Bio, Inc. |
Compositions, methods and uses of messenger rna
|
|
US20210145860A1
(en)
|
2019-10-21 |
2021-05-20 |
Translate Bio, Inc. |
Compositions, methods and uses of messenger rna
|
|
JP7306252B2
(ja)
*
|
2019-12-13 |
2023-07-11 |
東洋インキScホールディングス株式会社 |
紐状ミセル組成物および含水ゲル
|
|
EP4076400A1
(en)
|
2019-12-20 |
2022-10-26 |
Translate Bio, Inc. |
Improved process of preparing mrna-loaded lipid nanoparticles
|
|
CN115515559A
(zh)
|
2019-12-20 |
2022-12-23 |
翻译生物公司 |
信使rna的直肠递送
|
|
EP4076647A1
(en)
|
2019-12-20 |
2022-10-26 |
CureVac AG |
Lipid nanoparticles for delivery of nucleic acids
|
|
EP4103542A4
(en)
|
2020-01-09 |
2024-02-14 |
Guide Therapeutics, LLC |
NANOMATERIALS
|
|
WO2021142245A1
(en)
|
2020-01-10 |
2021-07-15 |
Translate Bio, Inc. |
Compounds, pharmaceutical compositions and methods for modulating expression of muc5b in lung cells and tissues
|
|
EP3886897A1
(en)
|
2020-02-04 |
2021-10-06 |
CureVac AG |
Coronavirus vaccine
|
|
CA3173035A1
(en)
|
2020-02-25 |
2021-09-02 |
Translate Bio, Inc. |
Improved processes of preparing mrna-loaded lipid nanoparticles
|
|
EP4114421A1
(en)
|
2020-03-02 |
2023-01-11 |
Tenaya Therapeutics, Inc. |
Gene vector control by cardiomyocyte-expressed micrornas
|
|
EP4114467A4
(en)
*
|
2020-03-02 |
2024-04-17 |
Trustees Of Tufts College |
Imidazole-based synthetic lipidoids for in vivo mrna delivery into immune cells
|
|
WO2021183720A1
(en)
|
2020-03-11 |
2021-09-16 |
Omega Therapeutics, Inc. |
Compositions and methods for modulating forkhead box p3 (foxp3) gene expression
|
|
US20230133587A1
(en)
*
|
2020-03-26 |
2023-05-04 |
Chinese Institute For Brain Research, Beijing |
Amino Acid Mediated Gene Delivery and Its Uses
|
|
WO2021226468A1
(en)
|
2020-05-07 |
2021-11-11 |
Translate Bio, Inc. |
Improved compositions for cftr mrna therapy
|
|
EP4146680A1
(en)
|
2020-05-07 |
2023-03-15 |
Translate Bio, Inc. |
Composition and methods for treatment of primary ciliary dyskinesia
|
|
KR20230008801A
(ko)
|
2020-05-07 |
2023-01-16 |
트랜슬레이트 바이오 인코포레이티드 |
Sars-cov-2 항원을 암호화하는 최적화된 뉴클레오티드 서열
|
|
EP4149556A1
(en)
|
2020-05-14 |
2023-03-22 |
Translate Bio, Inc. |
Peg lipidoid compounds
|
|
WO2021231901A1
(en)
|
2020-05-15 |
2021-11-18 |
Translate Bio, Inc. |
Lipid nanoparticle formulations for mrna delivery
|
|
AU2021275223A1
(en)
|
2020-05-20 |
2023-02-02 |
Flagship Pioneering Innovations Vi, Llc. |
Coronavirus antigen compositions and their uses
|
|
CA3179444A1
(en)
|
2020-05-20 |
2021-11-25 |
Avak Kahvejian |
Immunogenic compositions and uses thereof
|
|
CN111517974A
(zh)
*
|
2020-05-28 |
2020-08-11 |
浙江昂拓莱司生物技术有限公司 |
一种氨基酸n端烷基化衍生物及其制备方法和应用
|
|
CA3182026A1
(en)
|
2020-05-29 |
2021-12-02 |
Flagship Pioneering Innovations Vi, Llc. |
Trem compositions and methods relating thereto
|
|
JP2023530229A
(ja)
|
2020-05-29 |
2023-07-14 |
キュアバック エスイー |
核酸ベースの混合ワクチン
|
|
MX2022015042A
(es)
|
2020-05-29 |
2023-03-09 |
Flagship Pioneering Innovations Vi Llc |
Composiciones de trem y métodos relacionados con las mismas.
|
|
US20240307556A1
(en)
|
2020-07-02 |
2024-09-19 |
Maritime Therapeutics, Inc. |
Compositions and methods for reverse gene therapy
|
|
CA3189338A1
(en)
|
2020-07-16 |
2022-01-20 |
Acuitas Therapeutics, Inc. |
Cationic lipids for use in lipid nanoparticles
|
|
WO2022023559A1
(en)
|
2020-07-31 |
2022-02-03 |
Curevac Ag |
Nucleic acid encoded antibody mixtures
|
|
US11406703B2
(en)
|
2020-08-25 |
2022-08-09 |
Modernatx, Inc. |
Human cytomegalovirus vaccine
|
|
EP4157344A2
(en)
|
2020-08-31 |
2023-04-05 |
CureVac SE |
Multivalent nucleic acid based coronavirus vaccines
|
|
TW202218669A
(zh)
|
2020-09-03 |
2022-05-16 |
美商旗艦先鋒創新有限責任公司 |
免疫原性組成物及其用途
|
|
JP2023549011A
(ja)
|
2020-09-15 |
2023-11-22 |
ヴァーヴ・セラピューティクス,インコーポレーテッド |
遺伝子編集のための脂質製剤
|
|
CA3194863A1
(en)
|
2020-10-06 |
2022-04-14 |
Shrirang KARVE |
Improved process and formulation of lipid nanoparticles
|
|
US20220110884A1
(en)
|
2020-10-12 |
2022-04-14 |
Translate Bio, Inc. |
Process of preparing mrna-loaded lipid nanoparticles
|
|
WO2022081548A1
(en)
|
2020-10-12 |
2022-04-21 |
Translate Bio, Inc. |
Improved process of preparing ice-based lipid nanoparticles
|
|
US11771652B2
(en)
|
2020-11-06 |
2023-10-03 |
Sanofi |
Lipid nanoparticles for delivering mRNA vaccines
|
|
US20220160633A1
(en)
|
2020-11-09 |
2022-05-26 |
Translate Bio, Inc. |
Compositions for delivery of codon-optimized mrna
|
|
KR20230113580A
(ko)
|
2020-11-25 |
2023-07-31 |
트랜슬레이트 바이오 인코포레이티드 |
안정한 액체 지질 나노입자 제형
|
|
US11932705B2
(en)
|
2020-12-18 |
2024-03-19 |
Merck Sharp & Dohme Llc |
Cyclic polypeptides for PCSK9 inhibition
|
|
WO2022137133A1
(en)
|
2020-12-22 |
2022-06-30 |
Curevac Ag |
Rna vaccine against sars-cov-2 variants
|
|
CA3171051A1
(en)
|
2020-12-22 |
2022-06-30 |
Curevac Ag |
Pharmaceutical composition comprising lipid-based carriers encapsulating rna for multidose administration
|
|
US20240175020A1
(en)
|
2020-12-23 |
2024-05-30 |
Flagship Pioneering Innovations Vi, Llc |
Compositions of modified trems and uses thereof
|
|
EP4277929A1
(en)
|
2021-01-14 |
2023-11-22 |
Translate Bio, Inc. |
Methods and compositions for delivering mrna coded antibodies
|
|
EP4281114A4
(en)
*
|
2021-01-20 |
2025-08-06 |
Beam Therapeutics Inc |
IONIZABLE LIPIDS FOR NANOMATERIALS
|
|
EP4281080A4
(en)
|
2021-01-20 |
2025-09-24 |
Beam Therapeutics Inc |
NANOMATERIALS COMPRISING A BIODEGRADABLE ELEMENT
|
|
MX2023008333A
(es)
|
2021-01-20 |
2023-08-21 |
Beam Therapeutics Inc |
Nanomateriales.
|
|
CA3170747A1
(en)
|
2021-01-27 |
2022-08-04 |
Moritz THRAN |
Method of reducing the immunostimulatory properties of in vitro transcribed rna
|
|
US20240123076A1
(en)
|
2021-02-08 |
2024-04-18 |
The Board Of Regents Of The University Of Texas System |
Unsaturated dendrimers compositions, related formulations, and methods of use thereof
|
|
EP4291201A4
(en)
*
|
2021-02-10 |
2025-04-16 |
ElevateBio Technologies, Inc. |
Compounds, compositions, and methods of using thereof
|
|
KR20230175196A
(ko)
|
2021-03-23 |
2023-12-29 |
리코드 테라퓨틱스, 인크. |
폴리뉴클레오티드 조성물, 관련된 제제, 및 이의 사용 방법
|
|
WO2022204549A1
(en)
|
2021-03-25 |
2022-09-29 |
Translate Bio, Inc. |
Optimized nucleotide sequences encoding the extracellular domain of human ace2 protein or a portion thereof
|
|
WO2022200575A1
(en)
|
2021-03-26 |
2022-09-29 |
Glaxosmithkline Biologicals Sa |
Immunogenic compositions
|
|
US20250345524A1
(en)
|
2021-03-31 |
2025-11-13 |
CureVac SE |
Syringes containing pharmaceutical compositions comprising rna
|
|
KR20230165276A
(ko)
|
2021-03-31 |
2023-12-05 |
플래그쉽 파이어니어링 이노베이션스 브이, 인크. |
타노트랜스미션 폴리펩티드 및 암의 치료에서의 이의 용도
|
|
WO2022225918A1
(en)
|
2021-04-19 |
2022-10-27 |
Translate Bio, Inc. |
Improved compositions for delivery of mrna
|
|
CA3171589A1
(en)
|
2021-05-03 |
2022-11-03 |
Moritz THRAN |
Improved nucleic acid sequence for cell type specific expression
|
|
EP4355308A1
(en)
|
2021-06-18 |
2024-04-24 |
Sanofi |
Multivalent influenza vaccines
|
|
JP2024527541A
(ja)
|
2021-07-01 |
2024-07-25 |
トランスレイト バイオ, インコーポレイテッド |
Mrnaの送達のための組成物
|
|
WO2023283359A2
(en)
|
2021-07-07 |
2023-01-12 |
Omega Therapeutics, Inc. |
Compositions and methods for modulating secreted frizzled receptor protein 1 (sfrp1) gene expression
|
|
EP4377457A1
(en)
|
2021-07-26 |
2024-06-05 |
Flagship Pioneering Innovations VI, LLC |
Trem compositions and uses thereof
|
|
US20240342206A1
(en)
|
2021-07-30 |
2024-10-17 |
CureVac SE |
mRNAS FOR TREATMENT OR PROPHYLAXIS OF LIVER DISEASES
|
|
US20240398933A1
(en)
|
2021-09-03 |
2024-12-05 |
CureVac SE |
Novel lipid nanoparticles for delivery of nucleic acids comprising phosphatidylserine
|
|
CA3230031A1
(en)
|
2021-09-03 |
2023-03-09 |
Patrick Baumhof |
Novel lipid nanoparticles for delivery of nucleic acids
|
|
TW202330916A
(zh)
|
2021-09-17 |
2023-08-01 |
美商旗艦先鋒創新有限責任公司 |
用於產生環狀多核糖核苷酸之組成物和方法
|
|
CA3234107A1
(en)
|
2021-10-05 |
2023-04-13 |
Florent PERAL |
Methods for freezing and freeze-drying lipid nanoparticles (lnps) and lnps obtained with the same
|
|
WO2023059806A1
(en)
|
2021-10-06 |
2023-04-13 |
Massachusetts Institute Of Technology |
Lipid nanoparticles for drug delivery to microglia in the brain
|
|
TW202322826A
(zh)
|
2021-10-18 |
2023-06-16 |
美商旗艦先鋒創新有限責任公司 |
用於純化多核糖核苷酸之組成物及方法
|
|
KR20240090727A
(ko)
|
2021-10-22 |
2024-06-21 |
세일 바이오메디슨스, 인크. |
Mrna 백신 조성물
|
|
US20250027108A1
(en)
|
2021-10-29 |
2025-01-23 |
CureVac SE |
Improved circular rna for expressing therapeutic proteins
|
|
EP4426343A1
(en)
|
2021-11-05 |
2024-09-11 |
Sanofi |
Respiratory syncytial virus rna vaccine
|
|
AU2022388747A1
(en)
|
2021-11-10 |
2024-06-20 |
Translate Bio, Inc. |
Composition and methods for treatment of primary ciliary dyskinesia
|
|
EP4436588A1
(en)
|
2021-11-23 |
2024-10-02 |
Sail Biomedicines, Inc. |
A bacteria-derived lipid composition and use thereof
|
|
EP4436598A2
(en)
|
2021-11-24 |
2024-10-02 |
Flagship Pioneering Innovations VI, LLC |
Immunogenic compositions and their uses
|
|
EP4436984A1
(en)
|
2021-11-24 |
2024-10-02 |
Flagship Pioneering Innovations VI, LLC |
Coronavirus immunogen compositions and their uses
|
|
CN118401544A
(zh)
|
2021-11-24 |
2024-07-26 |
旗舰创业创新六公司 |
水痘-带状疱疹病毒免疫原组合物及其用途
|
|
CA3239417A1
(en)
|
2021-11-30 |
2023-06-08 |
Yvonne CHAN |
Human metapneumovirus vaccines
|
|
WO2023114943A2
(en)
|
2021-12-16 |
2023-06-22 |
Acuitas Therapeutics, Inc. |
Lipids for use in lipid nanoparticle formulations
|
|
WO2023111262A1
(en)
|
2021-12-17 |
2023-06-22 |
Sanofi |
Lyme disease rna vaccine
|
|
US20240401024A1
(en)
|
2021-12-17 |
2024-12-05 |
Flagship Pioneering Innovations Vi, Llc |
Methods for enrichment of circular rna under denaturing conditions
|
|
JP2025500373A
(ja)
|
2021-12-20 |
2025-01-09 |
セイル バイオメディシンズ インコーポレイテッド |
Mrna治療用組成物
|
|
CA3241061A1
(en)
|
2021-12-22 |
2023-06-29 |
Alexandra Sophie DE BOER |
Compositions and methods for purifying polyribonucleotides
|
|
EP4452337A1
(en)
|
2021-12-23 |
2024-10-30 |
Flagship Pioneering Innovations VI, LLC |
Circular polyribonucleotides encoding antifusogenic polypeptides
|
|
KR20240148846A
(ko)
*
|
2022-01-20 |
2024-10-11 |
오하이오 스테이트 이노베이션 파운데이션 |
지질 화합물을 포함하는 조성물과 이의 제조 및 사용 방법
|
|
WO2023144193A1
(en)
|
2022-01-25 |
2023-08-03 |
CureVac SE |
Mrnas for treatment of hereditary tyrosinemia type i
|
|
US20250099614A1
(en)
|
2022-01-28 |
2025-03-27 |
CureVac SE |
Nucleic acid encoded transcription factor inhibitors
|
|
GB202202297D0
(en)
|
2022-02-21 |
2022-04-06 |
Verona Pharma Plc |
Formulation production process
|
|
WO2023161350A1
(en)
|
2022-02-24 |
2023-08-31 |
Io Biotech Aps |
Nucleotide delivery of cancer therapy
|
|
JP2025510229A
(ja)
|
2022-03-25 |
2025-04-14 |
セイル バイオメディシンズ インコーポレイテッド |
新規のイオン化脂質および脂質ナノ粒子ならびにそれらを使用する方法
|
|
JP2025511756A
(ja)
|
2022-04-08 |
2025-04-16 |
フラッグシップ パイオニアリング イノベーションズ セブン,エルエルシー |
ワクチン及び関連する方法
|
|
CN119325466A
(zh)
*
|
2022-04-08 |
2025-01-17 |
尚威天成信使核糖核酸治疗公司 |
可电离脂质化合物和脂质纳米颗粒组合物
|
|
KR20250008765A
(ko)
|
2022-05-06 |
2025-01-15 |
사노피 |
핵산 백신에 대한 신호 서열
|
|
CA3257006A1
(en)
|
2022-05-09 |
2023-11-16 |
Flagship Pioneering Innovations Vi, Llc |
TREM COMPOSITIONS AND METHODS OF USE FOR TREATING PROLIFERATIVE DISORDERS
|
|
TW202409283A
(zh)
|
2022-05-13 |
2024-03-01 |
美商旗艦先鋒創新有限責任(Vii)公司 |
雙股dna組合物及相關方法
|
|
EP4531902A1
(en)
|
2022-05-25 |
2025-04-09 |
CureVac SE |
Nucleic acid based vaccine encoding an escherichia coli fimh antigenic polypeptide
|
|
WO2023232147A1
(zh)
*
|
2022-06-02 |
2023-12-07 |
厦门赛诺邦格生物科技股份有限公司 |
一种氨基酸阳离子脂质
|
|
CN117460711B
(zh)
*
|
2022-06-02 |
2025-07-08 |
厦门赛诺邦格生物科技股份有限公司 |
一种含有不饱和键的氨基酸阳离子脂质
|
|
WO2023250112A1
(en)
|
2022-06-22 |
2023-12-28 |
Flagship Pioneering Innovations Vi, Llc |
Compositions of modified trems and uses thereof
|
|
CA3260606A1
(en)
|
2022-06-30 |
2024-01-04 |
Sanofi |
NEW PEPTIDES FOR USE AS SELECTIVE IL-23 RECEPTOR ANTAGONISTS
|
|
IL317826A
(en)
|
2022-07-20 |
2025-02-01 |
Beam Therapeutics Inc |
Nanomaterials include triols
|
|
KR20250044720A
(ko)
|
2022-08-01 |
2025-04-01 |
플래그쉽 파이어니어링 이노베이션스 Vii, 엘엘씨 |
면역조절 단백질 및 관련 방법
|
|
CN119947710A
(zh)
|
2022-08-04 |
2025-05-06 |
赛诺菲巴斯德有限公司 |
Rna包封的定量评估
|
|
WO2024035952A1
(en)
|
2022-08-12 |
2024-02-15 |
Remix Therapeutics Inc. |
Methods and compositions for modulating splicing at alternative splice sites
|
|
JP2025529906A
(ja)
|
2022-08-22 |
2025-09-09 |
ザ ヘンリー エム ジャクソン ファンデイション フォー ザ アドヴァンスメント オブ ミリタリー メディシン インコーポレイテッド |
コロナウイルスに対するワクチン
|
|
CN120239693A
(zh)
|
2022-08-31 |
2025-07-01 |
赛欧生物医药股份有限公司 |
新型可电离脂质和脂质纳米颗粒以及其使用方法
|
|
CA3267272A1
(en)
|
2022-09-26 |
2024-04-04 |
Glaxosmithkline Biologicals Sa |
FLU VIRUS VACCINES
|
|
US20240174732A1
(en)
|
2022-10-05 |
2024-05-30 |
Flagship Pioneering Innovations V, Inc. |
Nucleic acid molecules encoding trif and additional polypeptides and their use in treating cancer
|
|
DE202023106198U1
(de)
|
2022-10-28 |
2024-03-21 |
CureVac SE |
Impfstoff auf Nukleinsäurebasis
|
|
AU2023372397A1
(en)
|
2022-10-31 |
2025-05-08 |
Flagship Pioneering Innovations Vi, Llc |
Compositions and methods for purifying polyribonucleotides
|
|
AU2023374764A1
(en)
|
2022-11-04 |
2025-06-19 |
Sanofi Pasteur Inc. |
Respiratory syncytial virus rna vaccination
|
|
AR131008A1
(es)
|
2022-11-08 |
2025-02-05 |
Flagship Pioneering Innovations Vi Llc |
Composiciones y métodos para producir polirribonucleótidos circulares
|
|
CN120359023A
(zh)
|
2022-11-10 |
2025-07-22 |
赛欧生物医药股份有限公司 |
包含脂质纳米颗粒或脂质重构的天然信使包的rna组合物
|
|
WO2024112652A1
(en)
|
2022-11-21 |
2024-05-30 |
Translate Bio, Inc. |
Compositions of dry powder formulations of messenger rna and methods of use thereof
|
|
AU2023391361A1
(en)
|
2022-12-08 |
2025-06-05 |
Recode Therapeutics, Inc. |
Lipid nanoparticle compositions and uses thereof
|
|
TW202430215A
(zh)
|
2022-12-14 |
2024-08-01 |
美商旗艦先鋒創新有限責任(Vii)公司 |
用於將治療劑遞送至骨之組成物和方法
|
|
CN120344258A
(zh)
|
2022-12-15 |
2025-07-18 |
赛诺菲巴斯德有限公司 |
编码流感病毒样颗粒的mRNA
|
|
TW202438514A
(zh)
|
2022-12-20 |
2024-10-01 |
法商賽諾菲公司 |
鼻病毒mrna疫苗
|
|
US20240238473A1
(en)
|
2023-01-09 |
2024-07-18 |
Beth Israel Deaconess Medical Center, Inc. |
Recombinant nucleic acid molecules and their use in wound healing
|
|
US20240269251A1
(en)
|
2023-01-09 |
2024-08-15 |
Flagship Pioneering Innovations V, Inc. |
Genetic switches and their use in treating cancer
|
|
EP4648794A2
(en)
|
2023-01-09 |
2025-11-19 |
Flagship Pioneering Innovations VII, LLC |
Vaccines and related methods
|
|
WO2024151685A1
(en)
|
2023-01-09 |
2024-07-18 |
Beth Israel Deaconess Medical Center, Inc. |
Recombinant nucleic acid molecules and their use in wound healing
|
|
EP4654952A1
(en)
|
2023-01-27 |
2025-12-03 |
Sail Biomedicines, Inc. |
A modified lipid composition and uses thereof
|
|
EP4658239A1
(en)
|
2023-02-03 |
2025-12-10 |
GlaxoSmithKline Biologicals S.A. |
Rna formulation
|
|
TW202438515A
(zh)
|
2023-02-06 |
2024-10-01 |
美商旗艦先鋒創新有限責任(Vii)公司 |
免疫調節組合物及相關方法
|
|
IL322468A
(en)
|
2023-02-13 |
2025-09-01 |
Flagship Pioneering Innovations Vii Llc |
Ionizable lipids containing degradable crosslinkers and lipid carriers for therapeutic compositions
|
|
GB202302092D0
(en)
|
2023-02-14 |
2023-03-29 |
Glaxosmithkline Biologicals Sa |
Analytical method
|
|
WO2024173828A1
(en)
|
2023-02-17 |
2024-08-22 |
Flagship Pioneering Innovations Vii, Llc |
Dna compositions comprising modified uracil
|
|
WO2024173836A2
(en)
|
2023-02-17 |
2024-08-22 |
Flagship Pioneering Innovations Vii, Llc |
Dna compositions comprising modified cytosine
|
|
WO2024177424A1
(ko)
*
|
2023-02-24 |
2024-08-29 |
에스티팜 주식회사 |
신규 이온화 가능한 지질 및 이를 포함하는 지질나노입자
|
|
US12263213B2
(en)
|
2023-03-02 |
2025-04-01 |
Sanofi Pasteur |
Compositions for use in treatment of Chlamydia
|
|
DE112024001143T5
(de)
|
2023-03-08 |
2025-12-18 |
CureVac SE |
Neue lipid-nanopartikel-formeln für die abgabe von nukleinsäuren
|
|
WO2024192422A1
(en)
|
2023-03-15 |
2024-09-19 |
Flagship Pioneering Innovations Vi, Llc |
Immunogenic compositions and uses thereof
|
|
AU2024235803A1
(en)
|
2023-03-15 |
2025-09-25 |
Flagship Pioneering Innovations Vi, Llc |
Compositions comprising polyribonucleotides and uses thereof
|
|
AU2024255972A1
(en)
|
2023-04-12 |
2025-10-23 |
Flagship Pioneering Innovations Vi, Llc |
Modified trems, compositions, and related methods thereof
|
|
AU2024252590A1
(en)
|
2023-04-12 |
2025-10-23 |
Flagship Pioneering Innovations Vi, Llc |
Trems for use in correction of missense mutations
|
|
KR20250169625A
(ko)
|
2023-04-17 |
2025-12-03 |
사노피 파스퇴르 인크 |
재구성 가능한 건조 분말 제형 및 이의 사용 방법
|
|
WO2024220625A1
(en)
|
2023-04-19 |
2024-10-24 |
Sail Biomedicines, Inc. |
Delivery of polynucleotides from lipid nanoparticles comprising rna and ionizable lipids
|
|
WO2024220712A2
(en)
|
2023-04-19 |
2024-10-24 |
Sail Biomedicines, Inc. |
Vaccine compositions
|
|
WO2024220752A2
(en)
|
2023-04-19 |
2024-10-24 |
Sail Biomedicines, Inc. |
Rna therapeutic compositions
|
|
WO2024220746A2
(en)
|
2023-04-21 |
2024-10-24 |
Flagship Pioneering Innovations Vii, Llc |
Rnai agents targeting fatty acid synthase and related methods
|
|
WO2024223724A1
(en)
|
2023-04-27 |
2024-10-31 |
Glaxosmithkline Biologicals Sa |
Influenza virus vaccines
|
|
CN121001738A
(zh)
|
2023-04-27 |
2025-11-21 |
葛兰素史克生物有限公司 |
流感病毒疫苗
|
|
TW202500750A
(zh)
|
2023-05-05 |
2025-01-01 |
法商賽諾菲公司 |
用於治療痤瘡的組成物
|
|
AR132662A1
(es)
|
2023-05-10 |
2025-07-16 |
Sanofi Sa |
Combinación de vacunas respiratorias de arnm
|
|
WO2024230934A1
(en)
|
2023-05-11 |
2024-11-14 |
CureVac SE |
Therapeutic nucleic acid for the treatment of ophthalmic diseases
|
|
WO2024243438A2
(en)
|
2023-05-23 |
2024-11-28 |
Omega Therapeutics, Inc. |
Compositions and methods for reducing cxcl9, cxcl10, and cxcl11 gene expression
|
|
WO2024246358A1
(en)
|
2023-06-01 |
2024-12-05 |
Sanofi |
Thermostable compositions comprising mrna lipid nanoparticles
|
|
WO2024258829A1
(en)
|
2023-06-12 |
2024-12-19 |
Flagship Pioneering Innovations Vii, Llc |
Sars-cov-2 vaccine compositions and related methods
|
|
TW202506117A
(zh)
|
2023-06-26 |
2025-02-16 |
英商維羅納製藥Plc公司 |
顆粒組成物
|
|
WO2025003760A1
(en)
|
2023-06-28 |
2025-01-02 |
Sanofi |
Sterol analogs in lipid nanoparticle formulations
|
|
WO2025006684A1
(en)
|
2023-06-28 |
2025-01-02 |
Flagship Pioneering Innovations Vi, Llc |
Circular polyribonucleotides encoding antifusogenic polypeptides
|
|
WO2025010554A1
(en)
*
|
2023-07-07 |
2025-01-16 |
Yoltech Therapeutics Co., Ltd. |
Lipid compounds for delivery of therapeutic agents and preparation method and its use thereof
|
|
WO2025011529A2
(en)
|
2023-07-07 |
2025-01-16 |
Shanghai Circode Biomed Co., Ltd. |
Circular rna vaccines for seasonal flu and methods of uses
|
|
WO2025017202A2
(en)
|
2023-07-19 |
2025-01-23 |
Sanofi |
Porphyromonas gingivalis antigenic constructs
|
|
WO2025024486A2
(en)
|
2023-07-25 |
2025-01-30 |
Flagship Pioneering Innovations Vii, Llc |
Cas endonucleases and related methods
|
|
WO2025042786A1
(en)
|
2023-08-18 |
2025-02-27 |
Flagship Pioneering Innovations Vi, Llc |
Compositions comprising circular polyribonucleotides and uses thereof
|
|
WO2025045142A1
(en)
|
2023-08-29 |
2025-03-06 |
Shanghai Circode Biomed Co., Ltd. |
Circular rna encoding vegf polypeptides, formulations, and methods of uses
|
|
WO2025049925A2
(en)
*
|
2023-09-01 |
2025-03-06 |
Poseida Therapeutics, Inc. |
Lipidoid compounds and related compositions and uses
|
|
EP4520345A1
(en)
|
2023-09-06 |
2025-03-12 |
Myneo Nv |
Product
|
|
TW202527960A
(zh)
|
2023-09-06 |
2025-07-16 |
美商賽諾菲巴斯德公司 |
經修飾b型流感血球凝集素多肽及核酸及其用途
|
|
WO2025054236A2
(en)
|
2023-09-06 |
2025-03-13 |
Flagship Pioneering Innovations Vii, Llc |
Sars-cov-2 vaccine compositions and related methods
|
|
WO2025051912A1
(en)
|
2023-09-08 |
2025-03-13 |
Sanofi |
New peptides as selective il-23 receptor inhibitors
|
|
WO2025051920A1
(en)
|
2023-09-08 |
2025-03-13 |
Sanofi |
New peptides as selective il-23 receptor inhibitors
|
|
TW202525266A
(zh)
|
2023-09-18 |
2025-07-01 |
美商旗艦先鋒創新有限責任(Vii)公司 |
可電離類脂質組成物及其治療用途
|
|
WO2025072331A1
(en)
|
2023-09-26 |
2025-04-03 |
Flagship Pioneering Innovations Vii, Llc |
Cas nucleases and related methods
|
|
WO2025090023A1
(en)
*
|
2023-10-24 |
2025-05-01 |
Agency For Science, Technology And Research |
A compound for preparing lipid nanoparticles encapsulating an agent, nanoparticle composition comprising said compound, and related methods thereof
|
|
WO2025096807A2
(en)
|
2023-10-31 |
2025-05-08 |
Flagship Pioneering Innovations Vii, Llc |
Novel therapeutic dna forms
|
|
US20250162981A1
(en)
|
2023-11-14 |
2025-05-22 |
Flagship Pioneering Innovations Vii, Llc |
Ionizable lipidoid compositions and therapeutic uses thereof
|
|
WO2025106915A1
(en)
|
2023-11-17 |
2025-05-22 |
Sail Biomedicines, Inc. |
Circular polyribonucleotides encoding glucagon-like peptide 1 (glp-1) and uses thereof
|
|
WO2025106930A1
(en)
|
2023-11-17 |
2025-05-22 |
Sail Biomedicines, Inc. |
Circular polyribonucleotides encoding glucagon-like peptide 2 (glp-2) and uses thereof
|
|
US20250161347A1
(en)
|
2023-11-22 |
2025-05-22 |
Flagship Pioneering Innovations Vii, Llc |
Methods and compositions for treating non-alcoholic fatty liver disease
|
|
WO2025117877A2
(en)
|
2023-12-01 |
2025-06-05 |
Flagship Pioneering Innovations Vii, Llc |
Cas nucleases and related methods
|
|
US12364773B2
(en)
|
2023-12-01 |
2025-07-22 |
Recode Therapeutics, Inc. |
Lipid nanoparticle compositions and uses thereof
|
|
WO2025132839A1
(en)
|
2023-12-21 |
2025-06-26 |
Glaxosmithkline Biologicals Sa |
Influenza virus vaccines
|
|
WO2025137646A1
(en)
|
2023-12-22 |
2025-06-26 |
Recode Therapeutics, Inc. |
Gene editing methods and compositions for treating cystic fibrosis
|
|
WO2025141521A1
(en)
|
2023-12-29 |
2025-07-03 |
Sanofi |
Lipids having dendritic moieties
|
|
WO2025160334A1
(en)
|
2024-01-26 |
2025-07-31 |
Flagship Pioneering Innovations Vii, Llc |
Immunoreceptor inhibitory proteins and related methods
|
|
WO2025194019A1
(en)
|
2024-03-14 |
2025-09-18 |
Flagship Pioneering Innovations Vii, Llc |
Methods for treating liver fibrosis and non-alcoholic fatty liver disease
|
|
WO2025196065A1
(en)
|
2024-03-20 |
2025-09-25 |
Sanofi |
Novel homocysteine based lipids and their use for delivery of nucleic acids
|
|
GB202404607D0
(en)
|
2024-03-29 |
2024-05-15 |
Glaxosmithkline Biologicals Sa |
RNA formulation
|
|
WO2025210592A1
(en)
|
2024-04-05 |
2025-10-09 |
Sanofi Pasteur Inc. |
Muscle cell lnp-mrna quality control assays
|
|
WO2025217275A2
(en)
|
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