|
ES2368941T3
(es)
|
2003-01-06 |
2011-11-23 |
Angiochem Inc. |
Angiopep-1, compuestos relacionados y utilizaciones correspondientes.
|
|
EP1912679A4
(en)
*
|
2005-06-15 |
2009-07-29 |
Massachusetts Inst Technology |
AMINOUS LIPIDS AND ITS USES
|
|
US9365634B2
(en)
|
2007-05-29 |
2016-06-14 |
Angiochem Inc. |
Aprotinin-like polypeptides for delivering agents conjugated thereto to tissues
|
|
JP5860698B2
(ja)
|
2008-04-18 |
2016-02-16 |
アンジオケム,インコーポレーテッド |
パクリタキセル、パクリタキセル類似体またはパクリタキセルコンジュゲートの医薬組成物ならびに関連する調製方法および使用方法
|
|
JP5705118B2
(ja)
|
2008-10-15 |
2015-04-22 |
アンジオケム インコーポレーテッド |
薬物送達のためのエトポシドおよびドキソルビシン複合体
|
|
EP2346906A4
(en)
|
2008-10-15 |
2013-04-24 |
Angiochem Inc |
CONJUGATES FROM GLP-1 AGONISTS AND THEIR USE
|
|
WO2010053572A2
(en)
|
2008-11-07 |
2010-05-14 |
Massachusetts Institute Of Technology |
Aminoalcohol lipidoids and uses thereof
|
|
JP5759379B2
(ja)
|
2008-12-05 |
2015-08-05 |
アンジオケム インコーポレーテッド |
ニューロテンシンまたはニューロテンシンアナログおよびその使用
|
|
WO2010069074A1
(en)
|
2008-12-17 |
2010-06-24 |
Universite Du Quebec A Montreal |
Membrane type-1 matrix metalloprotein inhibitors and uses thereof
|
|
EP2421562B1
(en)
|
2009-04-20 |
2019-03-13 |
Angiochem Inc. |
Treatment of ovarian cancer using an anticancer agent conjugated to an angiopep-2 analog
|
|
RU2012103240A
(ru)
|
2009-07-02 |
2013-08-10 |
Ангиокем Инк. |
Мультимерные пептидные конъюгаты и их применение
|
|
ME03091B
(me)
|
2009-12-01 |
2019-01-20 |
Translate Bio Inc |
Isporuka irnk za povećanje ekspresije proteina i enzima u humanim genetskim oboljenjima
|
|
US8822663B2
(en)
|
2010-08-06 |
2014-09-02 |
Moderna Therapeutics, Inc. |
Engineered nucleic acids and methods of use thereof
|
|
US9193827B2
(en)
|
2010-08-26 |
2015-11-24 |
Massachusetts Institute Of Technology |
Poly(beta-amino alcohols), their preparation, and uses thereof
|
|
DK4108671T3
(da)
|
2010-10-01 |
2025-01-06 |
Modernatx Inc |
Modificerede nukleosider, nukleotider og nukleinsyrer samt anvendelser deraf
|
|
US9238716B2
(en)
|
2011-03-28 |
2016-01-19 |
Massachusetts Institute Of Technology |
Conjugated lipomers and uses thereof
|
|
JP2014511687A
(ja)
|
2011-03-31 |
2014-05-19 |
モデルナ セラピューティクス インコーポレイテッド |
工学操作された核酸の送達および製剤
|
|
PT2717893T
(pt)
|
2011-06-08 |
2019-08-20 |
Translate Bio Inc |
Composições de nanopartículas lipídicas e métodos para transferência de arnm
|
|
EP3998064A1
(en)
|
2011-06-08 |
2022-05-18 |
Translate Bio, Inc. |
Cleavable lipids
|
|
US9464124B2
(en)
|
2011-09-12 |
2016-10-11 |
Moderna Therapeutics, Inc. |
Engineered nucleic acids and methods of use thereof
|
|
JP6113737B2
(ja)
|
2011-10-03 |
2017-04-12 |
モデルナティエックス インコーポレイテッドModernaTX,Inc. |
修飾型のヌクレオシド、ヌクレオチドおよび核酸、ならびにそれらの使用方法
|
|
MX363734B
(es)
|
2011-10-27 |
2019-03-29 |
Massachusetts Inst Technology |
Derivados de aminoacidos funcionalizados en la terminal n capaces de formar microesferas encapsuladoras de farmaco.
|
|
KR20140102759A
(ko)
|
2011-12-16 |
2014-08-22 |
모더나 세라퓨틱스, 인코포레이티드 |
변형된 뉴클레오사이드, 뉴클레오타이드 및 핵산 조성물
|
|
US9572897B2
(en)
|
2012-04-02 |
2017-02-21 |
Modernatx, Inc. |
Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins
|
|
EP2834259A4
(en)
|
2012-04-02 |
2016-08-24 |
Moderna Therapeutics Inc |
MODIFIED POLYNUCLEOTIDES
|
|
US9254311B2
(en)
|
2012-04-02 |
2016-02-09 |
Moderna Therapeutics, Inc. |
Modified polynucleotides for the production of proteins
|
|
US9283287B2
(en)
|
2012-04-02 |
2016-03-15 |
Moderna Therapeutics, Inc. |
Modified polynucleotides for the production of nuclear proteins
|
|
US20150267192A1
(en)
|
2012-06-08 |
2015-09-24 |
Shire Human Genetic Therapies, Inc. |
Nuclease resistant polynucleotides and uses thereof
|
|
CA2884870C
(en)
|
2012-08-13 |
2022-03-29 |
Massachusetts Institute Of Technology |
Amine-containing lipidoids and uses thereof
|
|
US9597380B2
(en)
|
2012-11-26 |
2017-03-21 |
Modernatx, Inc. |
Terminally modified RNA
|
|
UA117466C2
(uk)
|
2012-12-13 |
2018-08-10 |
Мерк Шарп Енд Доме Корп. |
СТАБІЛЬНИЙ СКЛАД У ВИГЛЯДІ РОЗЧИНУ АНТИТІЛА ДО IL-23p19
|
|
US10258698B2
(en)
|
2013-03-14 |
2019-04-16 |
Modernatx, Inc. |
Formulation and delivery of modified nucleoside, nucleotide, and nucleic acid compositions
|
|
CA2904151C
(en)
|
2013-03-14 |
2023-09-12 |
Shire Human Genetic Therapies, Inc. |
Cftr mrna compositions and related methods and uses
|
|
HUE055044T2
(hu)
|
2013-03-14 |
2021-10-28 |
Translate Bio Inc |
MRNS-kódolt ellenanyagok bejuttatására szolgáló eljárások és készítmények
|
|
KR20150128687A
(ko)
|
2013-03-14 |
2015-11-18 |
샤이어 휴먼 지네틱 테라피즈 인크. |
메신저 rna의 정제 방법
|
|
WO2014152030A1
(en)
|
2013-03-15 |
2014-09-25 |
Moderna Therapeutics, Inc. |
Removal of dna fragments in mrna production process
|
|
US8980864B2
(en)
|
2013-03-15 |
2015-03-17 |
Moderna Therapeutics, Inc. |
Compositions and methods of altering cholesterol levels
|
|
WO2014179562A1
(en)
|
2013-05-01 |
2014-11-06 |
Massachusetts Institute Of Technology |
1,3,5-triazinane-2,4,6-trione derivatives and uses thereof
|
|
AU2014315287A1
(en)
|
2013-09-03 |
2015-03-12 |
Moderna Therapeutics, Inc. |
Chimeric polynucleotides
|
|
EP3041938A1
(en)
|
2013-09-03 |
2016-07-13 |
Moderna Therapeutics, Inc. |
Circular polynucleotides
|
|
US10023626B2
(en)
|
2013-09-30 |
2018-07-17 |
Modernatx, Inc. |
Polynucleotides encoding immune modulating polypeptides
|
|
EP3052521A1
(en)
|
2013-10-03 |
2016-08-10 |
Moderna Therapeutics, Inc. |
Polynucleotides encoding low density lipoprotein receptor
|
|
CN105658800A
(zh)
*
|
2013-10-22 |
2016-06-08 |
夏尔人类遗传性治疗公司 |
Mrna的cns递送及其用途
|
|
EA201992208A1
(ru)
|
2013-10-22 |
2020-07-31 |
Транслейт Био, Инк. |
ЛЕЧЕНИЕ ФЕНИЛКЕТОНУРИИ С ПРИМЕНЕНИЕМ мРНК
|
|
WO2015061467A1
(en)
*
|
2013-10-22 |
2015-04-30 |
Shire Human Genetic Therapies, Inc. |
Lipid formulations for delivery of messenger rna
|
|
BR112016009014B1
(pt)
*
|
2013-10-22 |
2024-02-06 |
Translate Bio, Inc |
USO DE COMPOSIÇÃO COMPREENDENDO mRNA PARA DEFICIÊNCIA DE ARGININOSSUCINATO SINTETASE
|
|
WO2015138357A2
(en)
|
2014-03-09 |
2015-09-17 |
The Trustees Of The University Of Pennsylvania |
Compositions useful in treatment of otc deficency
|
|
JP6372118B2
(ja)
*
|
2014-03-18 |
2018-08-15 |
東洋インキScホールディングス株式会社 |
両性界面活性剤とその製造方法
|
|
ES2774552T3
(es)
|
2014-03-24 |
2020-07-21 |
Translate Bio Inc |
Terapia de ARNm para el tratamiento de enfermedades oculares
|
|
RU2021109685A
(ru)
|
2014-04-23 |
2021-04-13 |
МОДЕРНАТиЭкс, ИНК. |
Вакцины на основе нуклеиновых кислот
|
|
KR102739894B1
(ko)
|
2014-04-25 |
2024-12-05 |
샤이어 휴먼 지네틱 테라피즈 인크. |
메신저 rna 의 정제 방법
|
|
US10022455B2
(en)
|
2014-05-30 |
2018-07-17 |
Translate Bio, Inc. |
Biodegradable lipids for delivery of nucleic acids
|
|
CA2951707A1
(en)
|
2014-06-10 |
2015-12-17 |
Massachusetts Institute Of Technology |
Method for gene editing
|
|
AU2015279968B2
(en)
*
|
2014-06-24 |
2019-11-14 |
Translate Bio, Inc. |
Stereochemically enriched compositions for delivery of nucleic acids
|
|
CN106456547B
(zh)
|
2014-07-02 |
2021-11-12 |
川斯勒佰尔公司 |
信使rna的包封
|
|
WO2016004202A1
(en)
|
2014-07-02 |
2016-01-07 |
Massachusetts Institute Of Technology |
Polyamine-fatty acid derived lipidoids and uses thereof
|
|
EP3169693B1
(en)
|
2014-07-16 |
2022-03-09 |
ModernaTX, Inc. |
Chimeric polynucleotides
|
|
EP3171895A1
(en)
|
2014-07-23 |
2017-05-31 |
Modernatx, Inc. |
Modified polynucleotides for the production of intrabodies
|
|
WO2016025643A1
(en)
|
2014-08-12 |
2016-02-18 |
Massachusetts Institute Of Technology |
Brush-poly(glycoamidoamine)-lipids and uses thereof
|
|
WO2016090262A1
(en)
|
2014-12-05 |
2016-06-09 |
Shire Human Genetic Therapies, Inc. |
Messenger rna therapy for treatment of articular disease
|
|
US10172924B2
(en)
|
2015-03-19 |
2019-01-08 |
Translate Bio, Inc. |
MRNA therapy for pompe disease
|
|
ES2880103T3
(es)
*
|
2015-05-21 |
2021-11-23 |
Ohio State Innovation Foundation |
Derivados de benceno-1, 3, 5-tricarboxamida y usos de los mismos
|
|
CA2989400A1
(en)
|
2015-06-15 |
2016-12-22 |
Angiochem Inc. |
Ang1005 for the treatment of leptomeningeal carcinomatosis
|
|
CA2990172A1
(en)
*
|
2015-06-19 |
2016-12-22 |
Massachusetts Institute Of Technology |
Alkenyl substituted 2,5-piperazinediones and their use in compositions for delivering an agent to a subject or cell
|
|
WO2017031232A1
(en)
|
2015-08-17 |
2017-02-23 |
Modernatx, Inc. |
Methods for preparing particles and related compositions
|
|
MA47016A
(fr)
|
2015-10-22 |
2018-08-29 |
Modernatx Inc |
Vaccins contre les virus respiratoires
|
|
JP7687767B2
(ja)
|
2015-10-22 |
2025-06-03 |
モデルナティエックス インコーポレイテッド |
呼吸器合胞体ウイルスワクチン
|
|
CA3003103A1
(en)
|
2015-10-22 |
2017-04-27 |
Modernatx, Inc. |
Broad spectrum influenza virus vaccine
|
|
BR112018008090A2
(pt)
|
2015-10-22 |
2018-11-13 |
Modernatx Inc |
vacina de vírus do herpes simplex.
|
|
CA3002922A1
(en)
|
2015-10-22 |
2017-04-27 |
Modernatx, Inc. |
Human cytomegalovirus vaccine
|
|
JP6925688B2
(ja)
|
2015-10-22 |
2021-08-25 |
モデルナティーエックス, インコーポレイテッド |
水痘帯状疱疹ウイルス(vzv)のための核酸ワクチン
|
|
LT3394093T
(lt)
|
2015-12-23 |
2022-04-25 |
Modernatx, Inc. |
Ox40 ligandus koduojančių polinukleotidų naudojimo būdai
|
|
EP3400023A1
(en)
|
2016-01-10 |
2018-11-14 |
ModernaTX, Inc. |
Therapeutic mrnas encoding anti ctla-4 antibodies
|
|
CN109072223B
(zh)
|
2016-04-08 |
2022-10-21 |
川斯勒佰尔公司 |
多聚体编码核酸及其用途
|
|
KR102533456B1
(ko)
|
2016-05-18 |
2023-05-17 |
모더나티엑스, 인크. |
릴랙신을 인코딩하는 폴리뉴클레오타이드
|
|
LT3464336T
(lt)
|
2016-06-01 |
2022-05-10 |
Athira Pharma, Inc. |
Junginiai
|
|
EP3469074B1
(en)
|
2016-06-13 |
2020-12-09 |
Translate Bio, Inc. |
Messenger rna therapy for the treatment of ornithine transcarbamylase deficiency
|
|
IL308091B1
(en)
|
2016-09-13 |
2026-01-01 |
Allergan Inc |
Protein-free stabilized Clostridium toxin preparations
|
|
CA3041307A1
(en)
|
2016-10-21 |
2018-04-26 |
Giuseppe Ciaramella |
Human cytomegalovirus vaccine
|
|
US12491261B2
(en)
|
2016-10-26 |
2025-12-09 |
Acuitas Therapeutics, Inc. |
Lipid nanoparticle formulations
|
|
JP7738979B2
(ja)
|
2016-11-10 |
2025-09-16 |
トランスレイト バイオ, インコーポレイテッド |
Mrna担持脂質ナノ粒子を調製する改善されたプロセス
|
|
US11400109B2
(en)
|
2016-11-10 |
2022-08-02 |
Translate Bio, Inc. |
Subcutaneous delivery of messenger RNA
|
|
WO2018104540A1
(en)
|
2016-12-08 |
2018-06-14 |
Curevac Ag |
Rnas for wound healing
|
|
JP2020501545A
(ja)
|
2016-12-08 |
2020-01-23 |
キュアバック アーゲー |
肝疾患の処置または予防のためのrna
|
|
DK3585892T3
(da)
|
2017-02-27 |
2022-08-22 |
Translate Bio Inc |
Fremgangsmåder til oprensning af messenger-rna
|
|
MX2019010155A
(es)
|
2017-02-27 |
2020-12-10 |
Translate Bio Inc |
Arnm de cftr optimizado por codón novedoso.
|
|
WO2018157133A1
(en)
|
2017-02-27 |
2018-08-30 |
Translate Bio, Inc. |
Methods for purification of messenger rna
|
|
EP3592728A1
(en)
|
2017-03-07 |
2020-01-15 |
Translate Bio, Inc. |
Polyanionic delivery of nucleic acids
|
|
US11045540B2
(en)
*
|
2017-03-15 |
2021-06-29 |
Modernatx, Inc. |
Varicella zoster virus (VZV) vaccine
|
|
EP3607074A4
(en)
|
2017-04-05 |
2021-07-07 |
Modernatx, Inc. |
REDUCTION OR ELIMINATION OF IMMUNE RESPONSES TO NON-INTRAVENOUS THERAPEUTIC PROTEINS, FOR EXAMPLE SUBCUTANEOUSLY
|
|
WO2018200943A1
(en)
|
2017-04-28 |
2018-11-01 |
Acuitas Therapeutics, Inc. |
Novel carbonyl lipids and lipid nanoparticle formulations for delivery of nucleic acids
|
|
JOP20190260A1
(ar)
|
2017-05-02 |
2019-10-31 |
Merck Sharp & Dohme |
صيغ ثابتة لأجسام مضادة لمستقبل الموت المبرمج 1 (pd-1) وطرق استخدامها
|
|
AU2018263868A1
(en)
|
2017-05-02 |
2019-12-12 |
Merck Sharp & Dohme Llc |
Formulations of anti-LAG3 antibodies and co-formulations of anti-LAG3 antibodies and anti-PD-1 antibodies
|
|
WO2018213476A1
(en)
|
2017-05-16 |
2018-11-22 |
Translate Bio, Inc. |
Treatment of cystic fibrosis by delivery of codon-optimized mrna encoding cftr
|
|
US11786607B2
(en)
|
2017-06-15 |
2023-10-17 |
Modernatx, Inc. |
RNA formulations
|
|
EP3641834B1
(en)
|
2017-06-19 |
2023-10-04 |
Translate Bio, Inc. |
Messenger rna therapy for the treatment of friedreich's ataxia
|
|
WO2019036008A1
(en)
|
2017-08-16 |
2019-02-21 |
Acuitas Therapeutics, Inc. |
LIPIDS FOR USE IN LIPID NANOPARTICULAR FORMULATIONS
|
|
JP7461872B2
(ja)
|
2017-08-17 |
2024-04-04 |
アクイタス セラピューティクス インコーポレイテッド |
脂質ナノ粒子製剤における使用のための脂質
|
|
WO2019036030A1
(en)
|
2017-08-17 |
2019-02-21 |
Acuitas Therapeutics, Inc. |
LIPIDS FOR USE IN LIPID NANOPARTICLE FORMULATIONS
|
|
WO2019036028A1
(en)
|
2017-08-17 |
2019-02-21 |
Acuitas Therapeutics, Inc. |
LIPIDS FOR USE IN LIPID NANOPARTICULAR FORMULATIONS
|
|
AU2018326799A1
(en)
|
2017-08-31 |
2020-02-27 |
Modernatx, Inc. |
Methods of making lipid nanoparticles
|
|
EP4092038A1
(en)
|
2017-09-11 |
2022-11-23 |
Protagonist Therapeutics, Inc. |
Opioid agonist peptides and uses thereof
|
|
EP3461487A1
(en)
*
|
2017-09-29 |
2019-04-03 |
Nlife Therapeutics S.L. |
Compositions and methods for the delivery of mrna to hepatic cells
|
|
JP7356416B2
(ja)
|
2017-10-17 |
2023-10-04 |
サレプタ セラピューティクス, インコーポレイテッド |
二環式ペプチドオリゴヌクレオチドコンジュゲート
|
|
TW202423453A
(zh)
*
|
2017-10-17 |
2024-06-16 |
美商薩羅塔治療公司 |
用於反義遞送之細胞穿透肽
|
|
CN111386105B
(zh)
*
|
2017-11-06 |
2023-09-15 |
日东电工株式会社 |
用于递送生物活性分子的膜融合化合物
|
|
JP7273417B2
(ja)
|
2017-12-01 |
2023-05-15 |
スーチョウ リボ ライフ サイエンス カンパニー、リミテッド |
核酸、当該核酸を含む組成物および複合体ならびに調製方法と使用
|
|
US11414661B2
(en)
|
2017-12-01 |
2022-08-16 |
Suzhou Ribo Life Science Co., Ltd. |
Nucleic acid, composition and conjugate containing nucleic acid, preparation method therefor and use thereof
|
|
WO2019105418A1
(zh)
|
2017-12-01 |
2019-06-06 |
苏州瑞博生物技术有限公司 |
双链寡核苷酸、含双链寡核苷酸的组合物与缀合物及制备方法和用途
|
|
KR20250107294A
(ko)
|
2017-12-01 |
2025-07-11 |
쑤저우 리보 라이프 사이언스 컴퍼니, 리미티드 |
핵산, 이를 포함하는 조성물과 컨쥬게이트, 및 그의 제조 방법과 용도
|
|
WO2019105419A1
(zh)
|
2017-12-01 |
2019-06-06 |
苏州瑞博生物技术有限公司 |
一种核酸、含有该核酸的组合物与缀合物及制备方法和用途
|
|
WO2019126593A1
(en)
|
2017-12-20 |
2019-06-27 |
Translate Bio, Inc. |
Improved composition and methods for treatment of ornithine transcarbamylase deficiency
|
|
KR102128951B1
(ko)
*
|
2017-12-21 |
2020-07-01 |
탑월드(주) |
비즈왁스와 동식물성 오일을 함유하는 화장료 조성물
|
|
DK3732185T3
(da)
|
2017-12-29 |
2025-03-31 |
Suzhou Ribo Life Science Co Ltd |
Konjugater og fremstilling og anvendelse heraf
|
|
US11975110B2
(en)
|
2018-02-02 |
2024-05-07 |
Translate Bio, Inc. |
Cationic polymers
|
|
CN108467475B
(zh)
*
|
2018-03-08 |
2020-02-14 |
山西大学 |
一种环状聚合物及其制备方法和应用
|
|
WO2019178479A1
(en)
*
|
2018-03-16 |
2019-09-19 |
Sarepta Therapeutics, Inc. |
Chimeric peptides for antisense delivery
|
|
EP3793689A1
(en)
|
2018-05-15 |
2021-03-24 |
Translate Bio, Inc. |
Subcutaneous delivery of messenger rna
|
|
MA52625A
(fr)
|
2018-05-16 |
2021-03-24 |
Translate Bio Inc |
Lipides cationiques de ribose
|
|
CA3100254A1
(en)
|
2018-05-24 |
2019-11-28 |
Translate Bio, Inc. |
Thioester cationic lipids
|
|
WO2019232097A1
(en)
|
2018-05-30 |
2019-12-05 |
Translate Bio, Inc. |
Phosphoester cationic lipids
|
|
US20200016274A1
(en)
|
2018-05-30 |
2020-01-16 |
Translate Bio, Inc. |
Messenger rna vaccines and uses thereof
|
|
CA3100214A1
(en)
|
2018-05-30 |
2019-12-05 |
Translate Bio, Inc. |
Cationic lipids comprising a steroidal moiety
|
|
JP7441802B2
(ja)
|
2018-05-30 |
2024-03-01 |
トランスレイト バイオ, インコーポレイテッド |
ビタミンカチオン性脂質
|
|
CN108727209A
(zh)
*
|
2018-06-20 |
2018-11-02 |
复旦大学 |
具有n,n-二烷基亮氨酸结构的化合物及其制备方法
|
|
WO2019246386A1
(en)
|
2018-06-21 |
2019-12-26 |
Ra Pharmaceuticals Inc. |
Cyclic polypeptides for pcsk9 inhibition
|
|
JOP20190150A1
(ar)
|
2018-06-21 |
2019-12-21 |
Merck Sharp & Dohme |
مركبات مناهضة لـ pcsk9
|
|
EP3810196A4
(en)
|
2018-06-21 |
2022-05-04 |
Merck Sharp & Dohme Corp. |
CYCLIC POLYPEPTIDES FOR PCSK9 INHIBITION
|
|
EP3810178A4
(en)
|
2018-06-21 |
2022-05-04 |
Merck Sharp & Dohme Corp. |
CYCLIC POLYPEPTIDES TO INHIBIT PCSK9
|
|
US11306125B2
(en)
|
2018-06-21 |
2022-04-19 |
Merck Sharp & Dohme Corp. |
PCSK9 antagonists bicyclo-compounds
|
|
ES3015132T3
(en)
|
2018-06-21 |
2025-04-29 |
Ucb Holdings Inc |
Cyclic polypeptides for pcsk9 inhibition
|
|
WO2020023533A1
(en)
|
2018-07-23 |
2020-01-30 |
Translate Bio, Inc. |
Dry power formulations for messenger rna
|
|
JP2021534101A
(ja)
|
2018-08-09 |
2021-12-09 |
ヴェルソー セラピューティクス, インコーポレイテッド |
Ccr2及びcsf1rを標的とするためのオリゴヌクレオチド組成物ならびにその使用
|
|
EP3842534A4
(en)
|
2018-08-21 |
2022-07-06 |
Suzhou Ribo Life Science Co., Ltd. |
NUCLEIC ACID, PHARMACEUTICAL COMPOSITION AND CONJUGATE WITH NUCLEIC ACID AND THEIR USE
|
|
WO2020041793A1
(en)
|
2018-08-24 |
2020-02-27 |
Translate Bio, Inc. |
Methods for purification of messenger rna
|
|
AU2019333042B2
(en)
|
2018-08-29 |
2025-06-19 |
Translate Bio, Inc. |
Improved process of preparing mRNA-loaded lipid nanoparticles
|
|
KR20210102870A
(ko)
|
2018-08-30 |
2021-08-20 |
테나야 테라퓨틱스, 인코포레이티드 |
미오카르딘 및 ascl1을 사용한 심장 세포 재프로그래밍
|
|
EP3849617A1
(en)
|
2018-09-14 |
2021-07-21 |
Translate Bio, Inc. |
Composition and methods for treatment of methylmalonic acidemia
|
|
US12090235B2
(en)
|
2018-09-20 |
2024-09-17 |
Modernatx, Inc. |
Preparation of lipid nanoparticles and methods of administration thereof
|
|
EP4613367A1
(en)
|
2018-09-21 |
2025-09-10 |
Acuitas Therapeutics, Inc. |
Systems and methods for manufacturing lipid nanoparticles and liposomes
|
|
WO2020063198A1
(zh)
|
2018-09-30 |
2020-04-02 |
苏州瑞博生物技术有限公司 |
一种siRNA缀合物及其制备方法和用途
|
|
JP7467438B2
(ja)
|
2018-10-18 |
2024-04-15 |
メルク・シャープ・アンド・ドーム・エルエルシー |
抗rsv抗体の製剤及びその使用方法
|
|
CN112888451A
(zh)
|
2018-10-19 |
2021-06-01 |
川斯勒佰尔公司 |
信使rna的无泵包封
|
|
CN113015748B
(zh)
|
2018-10-31 |
2025-12-12 |
默沙东有限责任公司 |
抗人pd-1抗体晶体及其使用方法
|
|
CN113316458B
(zh)
|
2018-11-07 |
2024-08-02 |
默沙东有限责任公司 |
抗lag3抗体和抗pd-1抗体的共制剂
|
|
AU2019376004B2
(en)
|
2018-11-08 |
2025-12-18 |
Translate Bio, Inc. |
Methods and compositions for messenger RNA purification
|
|
US20220016265A1
(en)
|
2018-11-09 |
2022-01-20 |
Translate Bio, Inc. |
Messenger rna therapy for treatment of ocular diseases
|
|
US12280147B2
(en)
|
2018-11-09 |
2025-04-22 |
Translate Bio, Inc. |
PEG lipidoid compounds
|
|
AU2019377525B2
(en)
|
2018-11-09 |
2025-10-16 |
Translate Bio, Inc. |
Multi-PEG lipid compounds
|
|
JP7483294B2
(ja)
*
|
2018-11-09 |
2024-05-15 |
トランスレイト バイオ, インコーポレイテッド |
層間エステル、チオエステル、ジスルフィドおよび無水部分を含む2,5-ジオキソピペラジン脂質
|
|
CA3119449A1
(en)
|
2018-11-12 |
2020-05-22 |
Translate Bio, Inc. |
Methods for inducing immune tolerance
|
|
MX2021005969A
(es)
|
2018-11-21 |
2021-09-14 |
Translate Bio Inc |
Tratamiento de la fibrosis quística mediante el suministro de arnm que codifica cftr nebulizado.
|
|
US12257305B2
(en)
|
2018-11-21 |
2025-03-25 |
Translate Bio, Inc. |
Cationic lipid compounds
|
|
CA3118034A1
(en)
|
2018-12-21 |
2020-06-25 |
Curevac Ag |
Rna for malaria vaccines
|
|
JP7507495B2
(ja)
|
2018-12-28 |
2024-06-28 |
スーチョウ リボ ライフ サイエンス カンパニー、リミテッド |
核酸、当該核酸を含む組成物及び複合体ならびに調製方法と使用
|
|
JP2022516356A
(ja)
|
2019-01-07 |
2022-02-25 |
トランスレイト バイオ, インコーポレイテッド |
原発性線毛機能不全症の治療のための組成物および方法
|
|
WO2020161342A1
(en)
|
2019-02-08 |
2020-08-13 |
Curevac Ag |
Coding rna administered into the suprachoroidal space in the treatment of ophtalmic diseases
|
|
WO2020214946A1
(en)
|
2019-04-18 |
2020-10-22 |
Translate Bio, Inc. |
Cystine cationic lipids
|
|
US20220233444A1
(en)
|
2019-04-22 |
2022-07-28 |
Translate Bio, Inc. |
Thioester cationic lipids
|
|
EP3962902A1
(en)
|
2019-05-03 |
2022-03-09 |
Translate Bio, Inc. |
Di-thioester cationic lipids
|
|
WO2020232276A1
(en)
|
2019-05-14 |
2020-11-19 |
Translate Bio, Inc. |
Improved process of preparing mrna-loaded lipid nanoparticles
|
|
EP3974530A4
(en)
|
2019-05-22 |
2023-07-12 |
Suzhou Ribo Life Science Co., Ltd. |
NUCLEIC ACID, PHARMACEUTICAL COMPOSITION, CONJUGATE, METHOD OF MANUFACTURE AND USE
|
|
CA3139195A1
(en)
|
2019-05-22 |
2020-11-26 |
Suzhou Ribo Life Science Co., Ltd. |
Nucleic acid, pharmaceutical composition, conjugate, preparation method, and use
|
|
JP7610849B2
(ja)
|
2019-05-24 |
2025-01-09 |
スーチョウ リボ ライフ サイエンス カンパニー、リミテッド |
核酸、薬物組成物及び複合体ならびに調製方法と使用
|
|
EP3976593A1
(en)
|
2019-05-31 |
2022-04-06 |
Translate Bio, Inc. |
Macrocyclic lipids
|
|
WO2020254535A1
(en)
|
2019-06-18 |
2020-12-24 |
Curevac Ag |
Rotavirus mrna vaccine
|
|
CN114401942B
(zh)
|
2019-06-21 |
2024-01-26 |
川斯勒佰尔公司 |
三(羟甲基)甲基甘氨酸和柠檬酸脂质
|
|
WO2020257611A1
(en)
|
2019-06-21 |
2020-12-24 |
Translate Bio, Inc. |
Cationic lipids comprising an hydroxy moiety
|
|
JP7586886B2
(ja)
|
2019-07-08 |
2024-11-19 |
トランスレイト バイオ, インコーポレイテッド |
改善されたmRNA装填脂質ナノ粒子、およびそれを作製するプロセス
|
|
EP3997226A1
(en)
|
2019-07-11 |
2022-05-18 |
Tenaya Therapeutics, Inc. |
Cardiac cell reprogramming with micrornas and other factors
|
|
US12144871B2
(en)
|
2019-07-23 |
2024-11-19 |
Translate Bio, Inc. |
Stable compositions of MRNA-loaded lipid nanoparticles and processes of making
|
|
US12569438B2
(en)
|
2019-07-29 |
2026-03-10 |
Georgia Tech Research Corporation |
Nanomaterials containing constrained lipids and uses thereof
|
|
CA3148819A1
(en)
|
2019-07-30 |
2021-02-04 |
Translate Bio, Inc. |
Treatment of cystic fibrosis by delivery of nebulized mrna encoding cftr
|
|
JP2022544412A
(ja)
|
2019-08-14 |
2022-10-18 |
キュアバック アーゲー |
免疫賦活特性が減少したrna組み合わせおよび組成物
|
|
TW202123960A
(zh)
|
2019-08-30 |
2021-07-01 |
美商默沙東藥廠 |
Pcsk9拮抗劑化合物
|
|
US20240197825A1
(en)
|
2019-09-20 |
2024-06-20 |
Translate Bio, Inc. |
mRNA Encoding Engineered CFTR
|
|
CA3147643A1
(en)
|
2019-09-23 |
2021-04-01 |
Omega Therapeutics, Inc. |
Compositions and methods for modulating hepatocyte nuclear factor 4-alpha (hnf4.alpha.) gene expression
|
|
EP4048807A1
(en)
|
2019-09-23 |
2022-08-31 |
Omega Therapeutics, Inc. |
Compositions and methods for modulating apolipoprotein b (apob) gene expression
|
|
WO2021072172A1
(en)
|
2019-10-09 |
2021-04-15 |
Translate Bio, Inc. |
Compositions, methods and uses of messenger rna
|
|
WO2021081058A1
(en)
|
2019-10-21 |
2021-04-29 |
Translate Bio, Inc. |
Compositions, methods and uses of messenger rna
|
|
JP7306252B2
(ja)
*
|
2019-12-13 |
2023-07-11 |
東洋インキScホールディングス株式会社 |
紐状ミセル組成物および含水ゲル
|
|
EP4076492A4
(en)
|
2019-12-20 |
2024-01-17 |
Merck Sharp & Dohme LLC |
PCSK9 ANTAGONIST COMPOUNDS
|
|
WO2021127641A1
(en)
|
2019-12-20 |
2021-06-24 |
Translate Bio, Inc. |
Improved process of preparing mrna-loaded lipid nanoparticles
|
|
IL294073A
(en)
|
2019-12-20 |
2022-08-01 |
Translate Bio Inc |
Rectal administration of messenger rna
|
|
EP4076647A1
(en)
|
2019-12-20 |
2022-10-26 |
CureVac AG |
Lipid nanoparticles for delivery of nucleic acids
|
|
CN115175894B
(zh)
|
2020-01-09 |
2024-09-06 |
盖德治疗有限责任公司 |
纳米材料
|
|
WO2021142245A1
(en)
|
2020-01-10 |
2021-07-15 |
Translate Bio, Inc. |
Compounds, pharmaceutical compositions and methods for modulating expression of muc5b in lung cells and tissues
|
|
JP7793525B2
(ja)
|
2020-02-04 |
2026-01-05 |
キュアバック エスイー |
コロナウイルスワクチン
|
|
US11969480B2
(en)
*
|
2020-02-25 |
2024-04-30 |
Translate Bio, Inc. |
Processes of preparing mRNA-loaded lipid nanoparticles
|
|
US20230097743A1
(en)
*
|
2020-03-02 |
2023-03-30 |
Trustees Of Tufts College |
Imidazole-based synthetic lipidoids for in vivo mrna delivery into immune cells
|
|
CN115552022A
(zh)
|
2020-03-02 |
2022-12-30 |
特纳亚治疗股份有限公司 |
由心肌细胞表达的微rna控制的基因载体
|
|
EP4118207A1
(en)
|
2020-03-11 |
2023-01-18 |
Omega Therapeutics, Inc. |
Compositions and methods for modulating forkhead box p3 (foxp3) gene expression
|
|
US20230133587A1
(en)
*
|
2020-03-26 |
2023-05-04 |
Chinese Institute For Brain Research, Beijing |
Amino Acid Mediated Gene Delivery and Its Uses
|
|
WO2021226436A1
(en)
|
2020-05-07 |
2021-11-11 |
Translate Bio, Inc. |
Optimized nucleotide sequences encoding sars-cov-2 antigens
|
|
EP4146680A1
(en)
|
2020-05-07 |
2023-03-15 |
Translate Bio, Inc. |
Composition and methods for treatment of primary ciliary dyskinesia
|
|
WO2021226468A1
(en)
|
2020-05-07 |
2021-11-11 |
Translate Bio, Inc. |
Improved compositions for cftr mrna therapy
|
|
US12514932B2
(en)
|
2020-05-14 |
2026-01-06 |
Translate Bio, Inc. |
PEG lipidoid compounds
|
|
WO2021231901A1
(en)
|
2020-05-15 |
2021-11-18 |
Translate Bio, Inc. |
Lipid nanoparticle formulations for mrna delivery
|
|
JP2023526422A
(ja)
|
2020-05-20 |
2023-06-21 |
フラッグシップ パイオニアリング イノベーションズ シックス,エルエルシー |
コロナウイルス抗原組成物及びそれらの使用
|
|
EP4153223A1
(en)
|
2020-05-20 |
2023-03-29 |
Flagship Pioneering Innovations VI, LLC |
Immunogenic compositions and uses thereof
|
|
CN111517974A
(zh)
*
|
2020-05-28 |
2020-08-11 |
浙江昂拓莱司生物技术有限公司 |
一种氨基酸n端烷基化衍生物及其制备方法和应用
|
|
AU2021281453A1
(en)
|
2020-05-29 |
2022-11-17 |
Flagship Pioneering Innovations Vi, Llc. |
Trem compositions and methods relating thereto
|
|
CN116322758A
(zh)
|
2020-05-29 |
2023-06-23 |
库尔维科欧洲股份公司 |
基于核酸的组合疫苗
|
|
CN116018405A
(zh)
|
2020-05-29 |
2023-04-25 |
旗舰先锋创新Vi有限责任公司 |
Trem组合物及其相关方法
|
|
WO2022006527A1
(en)
|
2020-07-02 |
2022-01-06 |
Maritime Therapeutics, Inc. |
Compositions and methods for reverse gene therapy
|
|
DK4182297T3
(da)
|
2020-07-16 |
2025-12-01 |
Acuitas Therapeutics Inc |
Kationiske lipider til brug i lipid-nanopartikler
|
|
EP4172194A1
(en)
|
2020-07-31 |
2023-05-03 |
CureVac SE |
Nucleic acid encoded antibody mixtures
|
|
US11406703B2
(en)
|
2020-08-25 |
2022-08-09 |
Modernatx, Inc. |
Human cytomegalovirus vaccine
|
|
US20240066114A1
(en)
|
2020-08-31 |
2024-02-29 |
CureVac SE |
Multivalent nucleic acid based coronavirus vaccines
|
|
MX2023002439A
(es)
|
2020-09-03 |
2023-05-09 |
Flagship Pioneering Innovations Vi Llc |
Composiciones immunogénicas y usos de las mismas.
|
|
JP2023549011A
(ja)
|
2020-09-15 |
2023-11-22 |
ヴァーヴ・セラピューティクス,インコーポレーテッド |
遺伝子編集のための脂質製剤
|
|
JP2023544197A
(ja)
|
2020-10-06 |
2023-10-20 |
トランスレイト バイオ, インコーポレイテッド |
脂質ナノ粒子の改善された方法および製剤
|
|
WO2022081544A1
(en)
|
2020-10-12 |
2022-04-21 |
Translate Bio, Inc. |
Improved process of preparing mrna-loaded lipid nanoparticles
|
|
US20220133631A1
(en)
|
2020-10-12 |
2022-05-05 |
Translate Bio, Inc. |
Process of preparing ice-based lipid nanoparticles
|
|
TW202233232A
(zh)
|
2020-11-06 |
2022-09-01 |
法商賽諾菲公司 |
遞送mRNA疫苗的脂質奈米顆粒
|
|
AU2021373892A1
(en)
|
2020-11-09 |
2023-07-06 |
Translate Bio, Inc. |
Improved compositions for delivery of codon-optimized mrna
|
|
AU2021386737A1
(en)
|
2020-11-25 |
2023-07-13 |
Translate Bio, Inc. |
Stable liquid lipid nanoparticle formulations
|
|
US11932705B2
(en)
|
2020-12-18 |
2024-03-19 |
Merck Sharp & Dohme Llc |
Cyclic polypeptides for PCSK9 inhibition
|
|
WO2022135993A2
(en)
|
2020-12-22 |
2022-06-30 |
Curevac Ag |
Pharmaceutical composition comprising lipid-based carriers encapsulating rna for multidose administration
|
|
WO2022137133A1
(en)
|
2020-12-22 |
2022-06-30 |
Curevac Ag |
Rna vaccine against sars-cov-2 variants
|
|
KR20230135585A
(ko)
|
2020-12-23 |
2023-09-25 |
플래그쉽 파이어니어링 이노베이션스 브이아이, 엘엘씨 |
변형된 trem의 조성물 및 이의 용도
|
|
CN116981692A
(zh)
|
2021-01-14 |
2023-10-31 |
翻译生物公司 |
递送mRNA编码的抗体的方法和组合物
|
|
CN116847853A
(zh)
|
2021-01-20 |
2023-10-03 |
比姆医疗股份有限公司 |
包括可生物降解的特征的纳米材料
|
|
WO2022159463A1
(en)
|
2021-01-20 |
2022-07-28 |
Beam Therapeutics Inc. |
Nanomaterials
|
|
CN116782951A
(zh)
*
|
2021-01-20 |
2023-09-19 |
比姆医疗股份有限公司 |
用于纳米材料的可电离脂质
|
|
EP4087938A2
(en)
|
2021-01-27 |
2022-11-16 |
CureVac AG |
Method of reducing the immunostimulatory properties of in vitro transcribed rna
|
|
IL305021A
(en)
|
2021-02-08 |
2023-10-01 |
Univ Texas |
Unsaturated Dendrimer Compositions, Related Formulations, and Methods of Using Them
|
|
MX2023009345A
(es)
*
|
2021-02-10 |
2023-10-24 |
Oncorus Inc |
Compuestos, composiciones y metodos de uso de estos.
|
|
JP2024511437A
(ja)
|
2021-03-23 |
2024-03-13 |
リコード セラピューティクス,インク. |
ポリヌクレオチド組成物、関連製剤、およびその使用方法
|
|
US20250268994A1
(en)
|
2021-03-25 |
2025-08-28 |
Translate Bio, Inc. |
Optimized Nucleotide Sequences Encoding the Extracellular Domain of Human ACE2 Protein or a Portion Thereof
|
|
US20240181038A1
(en)
|
2021-03-26 |
2024-06-06 |
Glaxosmithkline Biologicals Sa |
Immunogenic compositions
|
|
CA3214085A1
(en)
|
2021-03-31 |
2022-10-06 |
Darby Rye Schmidt |
Thanotransmission polypeptides and their use in treating cancer
|
|
WO2022207862A2
(en)
|
2021-03-31 |
2022-10-06 |
Curevac Ag |
Syringes containing pharmaceutical compositions comprising rna
|
|
JP2024515668A
(ja)
|
2021-04-19 |
2024-04-10 |
トランスレイト バイオ, インコーポレイテッド |
Mrnaの送達のための改善された組成物
|
|
CA3171589A1
(en)
|
2021-05-03 |
2022-11-03 |
Moritz THRAN |
Improved nucleic acid sequence for cell type specific expression
|
|
KR20240022610A
(ko)
|
2021-06-18 |
2024-02-20 |
사노피 |
다가 인플루엔자 백신
|
|
EP4362920A1
(en)
|
2021-07-01 |
2024-05-08 |
Translate Bio, Inc. |
Compositions for delivery of mrna
|
|
WO2023283359A2
(en)
|
2021-07-07 |
2023-01-12 |
Omega Therapeutics, Inc. |
Compositions and methods for modulating secreted frizzled receptor protein 1 (sfrp1) gene expression
|
|
EP4377457A1
(en)
|
2021-07-26 |
2024-06-05 |
Flagship Pioneering Innovations VI, LLC |
Trem compositions and uses thereof
|
|
US20240342206A1
(en)
|
2021-07-30 |
2024-10-17 |
CureVac SE |
mRNAS FOR TREATMENT OR PROPHYLAXIS OF LIVER DISEASES
|
|
US20240398933A1
(en)
|
2021-09-03 |
2024-12-05 |
CureVac SE |
Novel lipid nanoparticles for delivery of nucleic acids comprising phosphatidylserine
|
|
EP4395748A1
(en)
|
2021-09-03 |
2024-07-10 |
CureVac SE |
Novel lipid nanoparticles for delivery of nucleic acids
|
|
AR127073A1
(es)
|
2021-09-17 |
2023-12-13 |
Flagship Pioneering Innovations Vi Llc |
Composiciones y métodos para producir polirribonucleótidos circulares
|
|
WO2023057444A1
(en)
|
2021-10-05 |
2023-04-13 |
Sanofi |
METHODS FOR FREEZING AND FREEZE-DRYING LIPID NANOPARTICLES (LNPs) AND LNPs OBTAINED WITH THE SAME
|
|
WO2023059806A1
(en)
|
2021-10-06 |
2023-04-13 |
Massachusetts Institute Of Technology |
Lipid nanoparticles for drug delivery to microglia in the brain
|
|
AU2022370530A1
(en)
|
2021-10-18 |
2024-05-02 |
Flagship Pioneering Innovations Vi, Llc |
Compositions and methods for purifying polyribonucleotides
|
|
JP2024539512A
(ja)
|
2021-10-22 |
2024-10-28 |
セイル バイオメディシンズ インコーポレイテッド |
Mrnaワクチン組成物
|
|
US20250027108A1
(en)
|
2021-10-29 |
2025-01-23 |
CureVac SE |
Improved circular rna for expressing therapeutic proteins
|
|
KR20240107146A
(ko)
|
2021-11-05 |
2024-07-08 |
사노피 |
호흡기 세포융합 바이러스 rna 백신
|
|
WO2023086893A1
(en)
|
2021-11-10 |
2023-05-19 |
Translate Bio, Inc. |
Composition and methods for treatment of primary ciliary dyskinesia
|
|
CN118488834A
(zh)
|
2021-11-23 |
2024-08-13 |
赛欧生物医药股份有限公司 |
细菌源性脂质组合物和其用途
|
|
JP2024541467A
(ja)
|
2021-11-24 |
2024-11-08 |
フラッグシップ パイオニアリング イノベーションズ シックス,エルエルシー |
コロナウイルス免疫原組成物及びそれらの使用
|
|
JP2024541466A
(ja)
|
2021-11-24 |
2024-11-08 |
フラッグシップ パイオニアリング イノベーションズ シックス,エルエルシー |
水痘帯状疱疹ウイルス免疫原組成物及びその使用
|
|
IL312965A
(en)
|
2021-11-24 |
2024-07-01 |
Flagship Pioneering Innovations Vi Llc |
Immunogenic compositions and their uses
|
|
KR20240118798A
(ko)
|
2021-11-30 |
2024-08-05 |
사노피 파스퇴르 인크 |
인간 메타뉴모바이러스 백신
|
|
WO2023114943A2
(en)
|
2021-12-16 |
2023-06-22 |
Acuitas Therapeutics, Inc. |
Lipids for use in lipid nanoparticle formulations
|
|
AU2022413687A1
(en)
|
2021-12-17 |
2024-06-27 |
Flagship Pioneering Innovations Vi, Llc |
Methods for enrichment of circular rna under denaturing conditions
|
|
CA3242439A1
(en)
|
2021-12-17 |
2023-06-22 |
Sanofi |
Lyme disease rna vaccine
|
|
EP4452239A1
(en)
|
2021-12-20 |
2024-10-30 |
Sail Biomedicines, Inc. |
Compositions comprising mrna and lipid reconstructed plant messenger packs
|
|
EP4453201A1
(en)
|
2021-12-22 |
2024-10-30 |
Flagship Pioneering Innovations VI, LLC |
Compositions and methods for purifying polyribonucleotides
|
|
JP2025500358A
(ja)
|
2021-12-23 |
2025-01-09 |
フラッグシップ パイオニアリング イノベーションズ シックス,エルエルシー |
抗膜融合ポリペプチドをコードする環状ポリリボヌクレオチド
|
|
US20250099392A1
(en)
*
|
2022-01-20 |
2025-03-27 |
Ohio State Innovation Foundation |
Compositions comprising lipid compounds and methods of making and use thereof
|
|
WO2023144193A1
(en)
|
2022-01-25 |
2023-08-03 |
CureVac SE |
Mrnas for treatment of hereditary tyrosinemia type i
|
|
EP4469091A1
(en)
|
2022-01-28 |
2024-12-04 |
CureVac SE |
Nucleic acid encoded transcription factor inhibitors
|
|
GB202202297D0
(en)
|
2022-02-21 |
2022-04-06 |
Verona Pharma Plc |
Formulation production process
|
|
EP4482962A1
(en)
|
2022-02-24 |
2025-01-01 |
IO Biotech ApS |
Nucleotide delivery of cancer therapy
|
|
US20250205167A1
(en)
|
2022-03-25 |
2025-06-26 |
Sail Biomedicines, Inc. |
Novel ionizable lipids and lipid nanoparticles and methods of using the same
|
|
JP2025511756A
(ja)
|
2022-04-08 |
2025-04-16 |
フラッグシップ パイオニアリング イノベーションズ セブン,エルエルシー |
ワクチン及び関連する方法
|
|
CN119325466A
(zh)
*
|
2022-04-08 |
2025-01-17 |
尚威天成信使核糖核酸治疗公司 |
可电离脂质化合物和脂质纳米颗粒组合物
|
|
CA3256624A1
(en)
|
2022-05-06 |
2023-11-09 |
Sanofi |
SIGNAL SEQUENCES FOR NUCLEIC ACID-BASED VACCINES
|
|
CA3257006A1
(en)
|
2022-05-09 |
2023-11-16 |
Flagship Pioneering Innovations Vi, Llc |
TREM COMPOSITIONS AND METHODS OF USE FOR TREATING PROLIFERATIVE DISORDERS
|
|
CN119487196A
(zh)
|
2022-05-13 |
2025-02-18 |
旗舰创业创新七公司 |
双链dna组合物及相关方法
|
|
US20250345407A1
(en)
|
2022-05-25 |
2025-11-13 |
CureVac SE |
Nucleic acid based vaccine encoding an escherichia coli fimh antigenic polypeptide
|
|
US20250288531A1
(en)
*
|
2022-06-02 |
2025-09-18 |
Xiamen Sinopeg Biotech Co., Ltd. |
Amino acid-based cationic lipid containing unsaturated bonds
|
|
CN120737001A
(zh)
*
|
2022-06-02 |
2025-10-03 |
厦门赛诺邦格生物科技股份有限公司 |
一种氨基酸阳离子脂质
|
|
EP4544043A1
(en)
|
2022-06-22 |
2025-04-30 |
Flagship Pioneering Innovations VI, LLC |
Compositions of modified trems and uses thereof
|
|
CA3260606A1
(en)
|
2022-06-30 |
2024-01-04 |
Sanofi |
NEW PEPTIDES FOR USE AS SELECTIVE IL-23 RECEPTOR ANTAGONISTS
|
|
AU2023311822A1
(en)
|
2022-07-20 |
2025-01-09 |
Beam Therapeutics Inc. |
Nanomaterials comprising triols
|
|
CA3261283A1
(en)
|
2022-08-01 |
2024-02-08 |
Flagship Pioneering Innovations Vii, Llc |
Immunomodulatory Proteins and Associated Methods
|
|
JP2025527277A
(ja)
|
2022-08-04 |
2025-08-20 |
サノフィ パスツール インコーポレイテッド |
Rnaカプセル化の定量的評価
|
|
WO2024035952A1
(en)
|
2022-08-12 |
2024-02-15 |
Remix Therapeutics Inc. |
Methods and compositions for modulating splicing at alternative splice sites
|
|
CA3265295A1
(en)
|
2022-08-22 |
2024-02-29 |
United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
CORONAVIRUS VACCINES
|
|
AU2023334610A1
(en)
|
2022-08-31 |
2025-03-13 |
Sail Biomedicines, Inc. |
Novel ionizable lipids and lipid nanoparticles and methods of using the same
|
|
JP2025532686A
(ja)
|
2022-09-26 |
2025-10-01 |
グラクソスミスクライン バイオロジカルズ ソシエテ アノニム |
インフルエンザウイルスワクチン
|
|
EP4598946A1
(en)
|
2022-10-05 |
2025-08-13 |
Flagship Pioneering Innovations V, Inc. |
Nucleic acid molecules encoding trif and additionalpolypeptides and their use in treating cancer
|
|
US12186389B2
(en)
|
2022-10-28 |
2025-01-07 |
Glaxosmithkline Biologicals Sa |
Nucleic acid base vaccine against emerging SARS-CoV-2 variants
|
|
WO2024097664A1
(en)
|
2022-10-31 |
2024-05-10 |
Flagship Pioneering Innovations Vi, Llc |
Compositions and methods for purifying polyribonucleotides
|
|
WO2024094881A1
(en)
|
2022-11-04 |
2024-05-10 |
Sanofi |
Respiratory syncytial virus rna vaccination
|
|
TW202434728A
(zh)
|
2022-11-08 |
2024-09-01 |
美商旗艦先鋒創新有限責任公司 |
用於產生環狀多核糖核苷酸的組成物和方法
|
|
WO2024102434A1
(en)
|
2022-11-10 |
2024-05-16 |
Senda Biosciences, Inc. |
Rna compositions comprising lipid nanoparticles or lipid reconstructed natural messenger packs
|
|
WO2024112652A1
(en)
|
2022-11-21 |
2024-05-30 |
Translate Bio, Inc. |
Compositions of dry powder formulations of messenger rna and methods of use thereof
|
|
CN120693181A
(zh)
|
2022-12-08 |
2025-09-23 |
瑞科德治疗公司 |
脂质纳米颗粒组合物及其用途
|
|
TW202430215A
(zh)
|
2022-12-14 |
2024-08-01 |
美商旗艦先鋒創新有限責任(Vii)公司 |
用於將治療劑遞送至骨之組成物和方法
|
|
AU2023394992A1
(en)
|
2022-12-15 |
2025-07-31 |
Sanofi Pasteur Inc. |
Mrna encoding influenza virus-like particle
|
|
AR131438A1
(es)
|
2022-12-20 |
2025-03-19 |
Sanofi Sa |
VACUNA DE ARNm DE RINOVIRUS
|
|
WO2024151687A1
(en)
|
2023-01-09 |
2024-07-18 |
Flagship Pioneering Innovations V, Inc. |
Genetic switches and their use in treating cancer
|
|
EP4648794A2
(en)
|
2023-01-09 |
2025-11-19 |
Flagship Pioneering Innovations VII, LLC |
Vaccines and related methods
|
|
US20240252520A1
(en)
|
2023-01-09 |
2024-08-01 |
Beth Israel Deaconess Medical Center, Inc. |
Therapeutic agents and their use for treating chronic wounds
|
|
WO2024151673A2
(en)
|
2023-01-09 |
2024-07-18 |
President And Fellows Of Harvard College |
Recombinant nucleic acid molecules and their use in wound healing
|
|
WO2024159172A1
(en)
|
2023-01-27 |
2024-08-02 |
Senda Biosciences, Inc. |
A modified lipid composition and uses thereof
|
|
WO2024160936A1
(en)
|
2023-02-03 |
2024-08-08 |
Glaxosmithkline Biologicals Sa |
Rna formulation
|
|
TW202438515A
(zh)
|
2023-02-06 |
2024-10-01 |
美商旗艦先鋒創新有限責任(Vii)公司 |
免疫調節組合物及相關方法
|
|
IL322468A
(en)
|
2023-02-13 |
2025-09-01 |
Flagship Pioneering Innovations Vii Llc |
Ionizable lipids containing degradable crosslinkers and lipid carriers for therapeutic compositions
|
|
GB202302092D0
(en)
|
2023-02-14 |
2023-03-29 |
Glaxosmithkline Biologicals Sa |
Analytical method
|
|
IL322201A
(en)
|
2023-02-17 |
2025-09-01 |
Flagship Pioneering Innovations Vii Llc |
DNA structures containing modified uracil
|
|
WO2024173836A2
(en)
|
2023-02-17 |
2024-08-22 |
Flagship Pioneering Innovations Vii, Llc |
Dna compositions comprising modified cytosine
|
|
KR102911928B1
(ko)
*
|
2023-02-24 |
2026-01-14 |
에스티팜 주식회사 |
신규 이온화 가능한 지질 및 이를 포함하는 지질나노입자
|
|
WO2024180262A1
(en)
|
2023-03-02 |
2024-09-06 |
Sanofi |
Compositions for use in treatment of chlamydia
|
|
AU2024233180A1
(en)
|
2023-03-08 |
2025-09-25 |
CureVac SE |
Novel lipid nanoparticle formulations for delivery of nucleic acids
|
|
CN121358494A
(zh)
|
2023-03-15 |
2026-01-16 |
旗舰创业创新第六有限责任公司 |
免疫原性组合物及其用途
|
|
KR20250162610A
(ko)
|
2023-03-15 |
2025-11-18 |
플래그쉽 파이어니어링 이노베이션스 브이아이, 엘엘씨 |
폴리리보뉴클레오티드를 포함하는 조성물 및 이의 용도
|
|
WO2024216128A1
(en)
|
2023-04-12 |
2024-10-17 |
Flagship Pioneering Innovations Vi, Llc |
Trems for use in correction of missense mutations
|
|
EP4695393A1
(en)
|
2023-04-12 |
2026-02-18 |
Flagship Pioneering Innovations VI, LLC |
Modified trems, compositions, and related methods thereof
|
|
EP4698156A1
(en)
|
2023-04-17 |
2026-02-25 |
Sanofi Pasteur Inc. |
Reconstitutable dry powder formulations and methods of use thereof
|
|
WO2024220752A2
(en)
|
2023-04-19 |
2024-10-24 |
Sail Biomedicines, Inc. |
Rna therapeutic compositions
|
|
WO2024220712A2
(en)
|
2023-04-19 |
2024-10-24 |
Sail Biomedicines, Inc. |
Vaccine compositions
|
|
WO2024220625A1
(en)
|
2023-04-19 |
2024-10-24 |
Sail Biomedicines, Inc. |
Delivery of polynucleotides from lipid nanoparticles comprising rna and ionizable lipids
|
|
WO2024220746A2
(en)
|
2023-04-21 |
2024-10-24 |
Flagship Pioneering Innovations Vii, Llc |
Rnai agents targeting fatty acid synthase and related methods
|
|
EP4701657A1
(en)
|
2023-04-27 |
2026-03-04 |
GlaxoSmithKline Biologicals S.A. |
Influenza virus vaccines
|
|
EP4701658A1
(en)
|
2023-04-27 |
2026-03-04 |
GlaxoSmithKline Biologicals S.A. |
Influenza virus vaccines
|
|
IL324411A
(en)
|
2023-05-05 |
2026-01-01 |
Sanofi Pasteur Inc |
Preparations for use in the treatment of acne
|
|
WO2024231565A1
(en)
|
2023-05-10 |
2024-11-14 |
Sanofi |
Combination respiratory mrna vaccines
|
|
WO2024230934A1
(en)
|
2023-05-11 |
2024-11-14 |
CureVac SE |
Therapeutic nucleic acid for the treatment of ophthalmic diseases
|
|
WO2024243438A2
(en)
|
2023-05-23 |
2024-11-28 |
Omega Therapeutics, Inc. |
Compositions and methods for reducing cxcl9, cxcl10, and cxcl11 gene expression
|
|
WO2024246358A1
(en)
|
2023-06-01 |
2024-12-05 |
Sanofi |
Thermostable compositions comprising mrna lipid nanoparticles
|
|
WO2024258829A1
(en)
|
2023-06-12 |
2024-12-19 |
Flagship Pioneering Innovations Vii, Llc |
Sars-cov-2 vaccine compositions and related methods
|
|
TW202506117A
(zh)
|
2023-06-26 |
2025-02-16 |
英商維羅納製藥Plc公司 |
顆粒組成物
|
|
WO2025006684A1
(en)
|
2023-06-28 |
2025-01-02 |
Flagship Pioneering Innovations Vi, Llc |
Circular polyribonucleotides encoding antifusogenic polypeptides
|
|
CN121712487A
(zh)
|
2023-06-28 |
2026-03-20 |
赛诺菲巴斯德有限公司 |
脂质纳米颗粒配制品中的固醇类似物
|
|
CN121532514A
(zh)
|
2023-07-07 |
2026-02-13 |
上海环码生物医药有限公司 |
用于季节性流感的环状rna疫苗及使用方法
|
|
WO2025010554A1
(en)
*
|
2023-07-07 |
2025-01-16 |
Yoltech Therapeutics Co., Ltd. |
Lipid compounds for delivery of therapeutic agents and preparation method and its use thereof
|
|
WO2025017202A2
(en)
|
2023-07-19 |
2025-01-23 |
Sanofi |
Porphyromonas gingivalis antigenic constructs
|
|
AU2024299627A1
(en)
|
2023-07-25 |
2026-01-22 |
Flagship Pioneering Innovations Vii, Llc |
Cas endonucleases and related methods
|
|
WO2025042786A1
(en)
|
2023-08-18 |
2025-02-27 |
Flagship Pioneering Innovations Vi, Llc |
Compositions comprising circular polyribonucleotides and uses thereof
|
|
WO2025045142A1
(en)
|
2023-08-29 |
2025-03-06 |
Shanghai Circode Biomed Co., Ltd. |
Circular rna encoding vegf polypeptides, formulations, and methods of uses
|
|
WO2025049925A2
(en)
*
|
2023-09-01 |
2025-03-06 |
Poseida Therapeutics, Inc. |
Lipidoid compounds and related compositions and uses
|
|
TW202527960A
(zh)
|
2023-09-06 |
2025-07-16 |
美商賽諾菲巴斯德公司 |
經修飾b型流感血球凝集素多肽及核酸及其用途
|
|
WO2025054236A2
(en)
|
2023-09-06 |
2025-03-13 |
Flagship Pioneering Innovations Vii, Llc |
Sars-cov-2 vaccine compositions and related methods
|
|
EP4520345A1
(en)
|
2023-09-06 |
2025-03-12 |
Myneo Nv |
Product
|
|
WO2025051912A1
(en)
|
2023-09-08 |
2025-03-13 |
Sanofi |
New peptides as selective il-23 receptor inhibitors
|
|
WO2025051920A1
(en)
|
2023-09-08 |
2025-03-13 |
Sanofi |
New peptides as selective il-23 receptor inhibitors
|
|
TW202525266A
(zh)
|
2023-09-18 |
2025-07-01 |
美商旗艦先鋒創新有限責任(Vii)公司 |
可電離類脂質組成物及其治療用途
|
|
WO2025072331A1
(en)
|
2023-09-26 |
2025-04-03 |
Flagship Pioneering Innovations Vii, Llc |
Cas nucleases and related methods
|
|
WO2025090023A1
(en)
*
|
2023-10-24 |
2025-05-01 |
Agency For Science, Technology And Research |
A compound for preparing lipid nanoparticles encapsulating an agent, nanoparticle composition comprising said compound, and related methods thereof
|
|
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|
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|
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(zh)
*
|
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