JP2014533181A - インサイチュー架橋性ポリマー組成物およびその方法 - Google Patents

インサイチュー架橋性ポリマー組成物およびその方法 Download PDF

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JP2014533181A
JP2014533181A JP2014541368A JP2014541368A JP2014533181A JP 2014533181 A JP2014533181 A JP 2014533181A JP 2014541368 A JP2014541368 A JP 2014541368A JP 2014541368 A JP2014541368 A JP 2014541368A JP 2014533181 A JP2014533181 A JP 2014533181A
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polymer composition
polymer
biocompatible polymer
weight
group
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JP2014541368A
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Japanese (ja)
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JP2014533181A5 (OSRAM
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ランドリナ、ジョセフ・エー．
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Cresilon Inc
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Cresilon Inc
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Publication of JP2014533181A publication Critical patent/JP2014533181A/ja
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0009—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
    • A61L26/0052—Mixtures of macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/001—Use of materials characterised by their function or physical properties
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0009—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
    • A61L26/0014—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0009—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
    • A61L26/0023—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0061—Use of materials characterised by their function or physical properties
    • A61L26/0066—Medicaments; Biocides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F283/00—Macromolecular compounds obtained by polymerising monomers on to polymers provided for in subclass C08G
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
    • C08L5/04—Alginic acid; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/04—Materials for stopping bleeding

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Materials Engineering (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Polymers & Plastics (AREA)
  • Surgery (AREA)
  • Inorganic Chemistry (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Dermatology (AREA)
  • Materials For Medical Uses (AREA)
  • Medicinal Preparation (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Dental Preparations (AREA)
JP2014541368A 2011-11-13 2012-11-12 インサイチュー架橋性ポリマー組成物およびその方法 Pending JP2014533181A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161559110P 2011-11-13 2011-11-13
US61/559,110 2011-11-13
PCT/US2012/064670 WO2013071235A1 (en) 2011-11-13 2012-11-12 In-situ cross-linkable polymeric compositions and methods thereof

Related Child Applications (1)

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JP2018120864A Division JP7013336B2 (ja) 2011-11-13 2018-06-26 インサイチュー架橋性ポリマー組成物およびその方法

Publications (2)

Publication Number Publication Date
JP2014533181A true JP2014533181A (ja) 2014-12-11
JP2014533181A5 JP2014533181A5 (OSRAM) 2016-01-07

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JP2014541368A Pending JP2014533181A (ja) 2011-11-13 2012-11-12 インサイチュー架橋性ポリマー組成物およびその方法
JP2018120864A Active JP7013336B2 (ja) 2011-11-13 2018-06-26 インサイチュー架橋性ポリマー組成物およびその方法
JP2020153716A Withdrawn JP2021007754A (ja) 2011-11-13 2020-09-14 インサイチュー架橋性ポリマー組成物およびその方法

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JP2020153716A Withdrawn JP2021007754A (ja) 2011-11-13 2020-09-14 インサイチュー架橋性ポリマー組成物およびその方法

Country Status (16)

Country Link
US (4) US20140287061A1 (OSRAM)
EP (1) EP2776068A4 (OSRAM)
JP (3) JP2014533181A (OSRAM)
KR (1) KR20140090670A (OSRAM)
CN (2) CN103930133A (OSRAM)
AU (2) AU2012334982A1 (OSRAM)
BR (1) BR112014011442A8 (OSRAM)
CA (1) CA2855347C (OSRAM)
HK (1) HK1201734A1 (OSRAM)
IL (1) IL232330B (OSRAM)
IN (1) IN2014CN03524A (OSRAM)
MX (2) MX366366B (OSRAM)
RU (2) RU2017144044A (OSRAM)
SG (2) SG11201402279SA (OSRAM)
WO (1) WO2013071235A1 (OSRAM)
ZA (1) ZA201403166B (OSRAM)

Cited By (6)

* Cited by examiner, † Cited by third party
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KR20180053636A (ko) * 2015-06-22 2018-05-23 크레실론, 인코퍼레이티드 고효율 지혈용 접착제 조성물 스캐폴드
JP2018162440A (ja) * 2017-03-27 2018-10-18 Jsr株式会社 組成物およびその用途
JP2020502241A (ja) * 2016-12-22 2020-01-23 オムリックス・バイオファーマシューティカルズ・リミテッドＯｍｒｉｘ Ｂｉｏｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｌｔｄ． アニオン交換体及びカルシウム塩を含む止血用組成物
JP2020078729A (ja) * 2015-06-22 2020-05-28 クレシロン， インコーポレイテッド 高度に有用な止血用接着性ポリマー足場
JP2022527348A (ja) * 2019-04-03 2022-06-01 ドテク－ソシエテ ア リスポンサビリタ リミタータ 皮膚病変の治療的処置のための二成分系組成物およびその生成方法
JP2023092390A (ja) * 2021-12-21 2023-07-03 富士フイルム株式会社 止血材組成物

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AU2008348311B2 (en) 2008-01-24 2014-06-26 University Of Utah Research Foundation Adhesive complex coacervates and methods of making and using thereof
CA2799818A1 (en) 2010-05-24 2011-12-01 University Of Utah Research Foundation Reinforced adhesive complex coacervates and methods of making and using thereof
JP2014502296A (ja) 2010-11-12 2014-01-30 ユニバーシティ・オブ・ユタ・リサーチ・ファウンデイション 単純接着剤コアセルベートならびにその製造方法および使用
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CN103611180B (zh) * 2013-11-21 2015-02-18 无锡中科光远生物材料有限公司 一种自粘止血防粘连纤维体的制备方法
JP6794343B2 (ja) 2014-07-11 2020-12-02 ザ ユナイテッド ステイツ オブ アメリカ， アズ リプレゼンテッド バイ ザ セクレタリー， デパートメント オブ ヘルス アンド ヒューマン サービシーズ 手術器具および眼組織移植方法
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US10660945B2 (en) 2015-08-07 2020-05-26 Victor Matthew Phillips Flowable hemostatic gel composition and its methods of use
CN105030815B (zh) * 2015-08-10 2019-03-15 贵州扬生医用器材有限公司 一种手术冲洗液及其制法
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KR101666792B1 (ko) 2016-02-05 2016-10-17 주식회사 파마리서치프로덕트 핵산 및 키토산을 포함하는 온도감응성 하이드로겔 조성물
US11298423B2 (en) * 2016-03-04 2022-04-12 University of Pittsburgh—of the Commonwealth System of Higher Education Protection and delivery of multiple therapeutic proteins
CN105860107B (zh) * 2016-04-26 2018-02-09 中南大学 一种过氧化氢响应及具有电化学活性的壳聚糖水凝胶的制备方法
KR101916193B1 (ko) * 2016-08-25 2018-11-07 주식회사 파마리서치프로덕트 핵산 및 키토산을 포함하는 관절강 주사용 조성물
EP3534867B1 (en) 2016-11-07 2025-06-04 Solventum Intellectual Properties Company Medical composition containing guanidinyl-containing polymer(s) and carrageenane(s)
WO2018119320A1 (en) * 2016-12-21 2018-06-28 Cresilon, Inc. Hemostatic compositions with antifibrinolytic agents
IL249725A0 (en) 2016-12-22 2017-03-30 Omrix Biopharmaceuticals Ltd A hemostatic preparation containing an anion exchanger and a calcium salt
CN108926490B (zh) * 2017-05-25 2021-01-26 南方医科大学南方医院 一种抗凝胃管的制作方法
KR102218427B1 (ko) * 2017-09-20 2021-02-22 차의과학대학교 산학협력단 단백질 약물을 포함하는 코아세르베이트 조성물 및 이를 포함하는 창상 치료제
CR20200366A (es) * 2018-01-26 2020-10-05 Polarityte Inc Sustrato acelarante de biomaterial con interfaz compuesta
CA3089480C (en) 2018-01-26 2025-05-27 Fluidx Medical Technology, Inc. APPARATUS AND METHOD FOR USING COMPLEX COACERVATES WITH IN SITU SOLIDIFICATION FOR VASCULAR OCLUSION
RU2675631C1 (ru) * 2018-10-02 2018-12-21 Общество с ограниченной ответственностью "Новые Биомедицинские Решения" Местное гемостатическое средство с повышенной антимикробной активностью
CN110157010B (zh) * 2019-05-05 2021-04-02 上海交通大学 一种基于多糖/聚肽的聚电解质复合物水凝胶止血剂
CN111303453B (zh) * 2020-03-09 2021-06-04 中国海洋大学 一种多重敏感型水凝胶聚合物的制备方法和应用
EP3925636A1 (en) 2020-06-17 2021-12-22 Centre Of Experimental Medicine Slovak Academy Of Sciences Institute Of Experimental Pharmacology Composite membranes containing a smart-released cytoprotectant targeting the inflamed tissue and use thereof
CN115887738B (zh) * 2022-12-16 2024-05-10 湖南师范大学 一种聚丙烯酰胺-壳聚糖/高岭土多孔材料及其制备方法

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