MX366366B - Composiciones polimericas reticulables in-situ y metodos de las mismas. - Google Patents
Composiciones polimericas reticulables in-situ y metodos de las mismas.Info
- Publication number
- MX366366B MX366366B MX2014005738A MX2014005738A MX366366B MX 366366 B MX366366 B MX 366366B MX 2014005738 A MX2014005738 A MX 2014005738A MX 2014005738 A MX2014005738 A MX 2014005738A MX 366366 B MX366366 B MX 366366B
- Authority
- MX
- Mexico
- Prior art keywords
- cross
- methods
- polymeric composition
- wound
- linking
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 5
- 238000000034 method Methods 0.000 title abstract 3
- 238000011065 in-situ storage Methods 0.000 title abstract 2
- 238000004132 cross linking Methods 0.000 abstract 2
- UXVMQQNJUSDDNG-UHFFFAOYSA-L Calcium chloride Chemical compound [Cl-].[Cl-].[Ca+2] UXVMQQNJUSDDNG-UHFFFAOYSA-L 0.000 abstract 1
- 229920001661 Chitosan Polymers 0.000 abstract 1
- 229920002307 Dextran Polymers 0.000 abstract 1
- 229920000615 alginic acid Polymers 0.000 abstract 1
- 235000010443 alginic acid Nutrition 0.000 abstract 1
- 229910001628 calcium chloride Inorganic materials 0.000 abstract 1
- 239000001110 calcium chloride Substances 0.000 abstract 1
- 239000003431 cross linking reagent Substances 0.000 abstract 1
- 230000023597 hemostasis Effects 0.000 abstract 1
- 239000011159 matrix material Substances 0.000 abstract 1
- 229920000447 polyanionic polymer Polymers 0.000 abstract 1
- 229920002851 polycationic polymer Polymers 0.000 abstract 1
- 238000003825 pressing Methods 0.000 abstract 1
- 238000007711 solidification Methods 0.000 abstract 1
- 230000008023 solidification Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
- A61L26/0009—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
- A61L26/0052—Mixtures of macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
- A61L24/001—Use of materials characterised by their function or physical properties
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
- A61L26/0009—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
- A61L26/0014—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
- A61L26/0009—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
- A61L26/0023—Polysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
- A61L26/0061—Use of materials characterised by their function or physical properties
- A61L26/0066—Medicaments; Biocides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F283/00—Macromolecular compounds obtained by polymerising monomers on to polymers provided for in subclass C08G
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
- C08L5/04—Alginic acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2400/00—Materials characterised by their function or physical properties
- A61L2400/04—Materials for stopping bleeding
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Materials Engineering (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Polymers & Plastics (AREA)
- Surgery (AREA)
- Inorganic Chemistry (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Dermatology (AREA)
- Materials For Medical Uses (AREA)
- Medicinal Preparation (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Dental Preparations (AREA)
Abstract
La presente invención se refiere a una composición polimérica para reticulada in situ en una herida que comprende 1) uno o más polímeros polianiónicos como los alginatos o hialuronatos capaces de ser reticuladas en la superficie de una herida y 2) uno o más polímeros policatiónicos como el quitosán o Dextrano-DEAE que ayuda en el proceso de solidificación y acelera la hemostasis sin necesidad de ejercer presión. La composición polimérica biocompatible puede comprender un agente reticulante como el cloruro de calcio acuoso. La invención abarca una composición polimérica inicial, la matriz solidificada reticulada e integrada a la zona de la herida, incluyendo los métodos de uso, aplicación y reticulación de la composición.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201161559110P | 2011-11-13 | 2011-11-13 | |
PCT/US2012/064670 WO2013071235A1 (en) | 2011-11-13 | 2012-11-12 | In-situ cross-linkable polymeric compositions and methods thereof |
Publications (2)
Publication Number | Publication Date |
---|---|
MX2014005738A MX2014005738A (es) | 2014-07-09 |
MX366366B true MX366366B (es) | 2019-07-05 |
Family
ID=48290658
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2014005738A MX366366B (es) | 2011-11-13 | 2012-11-12 | Composiciones polimericas reticulables in-situ y metodos de las mismas. |
MX2019008051A MX2019008051A (es) | 2011-11-13 | 2014-05-12 | Composiciones polimericas reticulables in-situ y metodos de las mismas. |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2019008051A MX2019008051A (es) | 2011-11-13 | 2014-05-12 | Composiciones polimericas reticulables in-situ y metodos de las mismas. |
Country Status (16)
Country | Link |
---|---|
US (4) | US20140287061A1 (es) |
EP (1) | EP2776068A4 (es) |
JP (3) | JP2014533181A (es) |
KR (1) | KR20140090670A (es) |
CN (2) | CN103930133A (es) |
AU (2) | AU2012334982A1 (es) |
BR (1) | BR112014011442A8 (es) |
CA (1) | CA2855347C (es) |
HK (1) | HK1201734A1 (es) |
IL (1) | IL232330B (es) |
IN (1) | IN2014CN03524A (es) |
MX (2) | MX366366B (es) |
RU (2) | RU2017144044A (es) |
SG (2) | SG10201610469QA (es) |
WO (1) | WO2013071235A1 (es) |
ZA (1) | ZA201403166B (es) |
Families Citing this family (35)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8283384B2 (en) | 2008-01-24 | 2012-10-09 | University Of Utah Research Foundation | Adhesive complex coacervates and methods of making and using thereof |
CA2712843A1 (en) | 2008-01-24 | 2009-07-30 | University Of Utah Research Foundation | Adhesive complex coacervates and methods of making and using thereof |
US20110287067A1 (en) | 2010-05-24 | 2011-11-24 | University Of Utah Research Foundation | Reinforced adhesive complex coacervates and methods of making and using thereof |
CN103179992A (zh) | 2010-11-12 | 2013-06-26 | 犹他大学研究基金会 | 简单的粘合剂凝聚层以及制备和使用方法 |
CA2855347C (en) | 2011-11-13 | 2019-03-05 | Suneris Inc. | In-situ cross-linkable polymeric compositions and methods thereof |
EP2953992B1 (en) | 2013-02-06 | 2021-11-24 | 3M Innovative Properties Company | Polymers, preparation and use thereof |
ITTO20130375A1 (it) * | 2013-05-10 | 2014-11-11 | Marco Benzi | Prodotto per l'uso per il trattamento terapeutico di parodontopatie e perimplantiti |
CN103611180B (zh) * | 2013-11-21 | 2015-02-18 | 无锡中科光远生物材料有限公司 | 一种自粘止血防粘连纤维体的制备方法 |
DK3166550T3 (da) | 2014-07-11 | 2024-01-29 | Us Health | Kirurgisk værktøj til okular vævstransplantation |
JP6742297B2 (ja) | 2014-07-14 | 2020-08-19 | ユニヴァーシティ オブ ユタ リサーチ ファンデーション | その場凝固複合コアセルベートならびにその製造および使用方法 |
BR112017027625A2 (pt) * | 2015-06-22 | 2018-08-28 | Cresilon, Inc. | matriz polimérica adesiva hemostática altamente eficaz |
JP7493961B2 (ja) * | 2015-06-22 | 2024-06-03 | クレシロン, インコーポレイテッド | 高度に有用な止血用接着性ポリマー足場 |
US10660945B2 (en) | 2015-08-07 | 2020-05-26 | Victor Matthew Phillips | Flowable hemostatic gel composition and its methods of use |
US10751444B2 (en) | 2015-08-07 | 2020-08-25 | Victor Matthew Phillips | Flowable hemostatic gel composition and its methods of use |
CN105030815B (zh) * | 2015-08-10 | 2019-03-15 | 贵州扬生医用器材有限公司 | 一种手术冲洗液及其制法 |
US11065337B2 (en) | 2015-12-14 | 2021-07-20 | University of Pittsburgh—of the Commonwealth System of Higher Education | Complex coacervate for controlled release and related methods |
KR101666792B1 (ko) | 2016-02-05 | 2016-10-17 | 주식회사 파마리서치프로덕트 | 핵산 및 키토산을 포함하는 온도감응성 하이드로겔 조성물 |
WO2017152039A1 (en) | 2016-03-04 | 2017-09-08 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Protection and delivery of multiple therapeutic proteins |
CN105860107B (zh) * | 2016-04-26 | 2018-02-09 | 中南大学 | 一种过氧化氢响应及具有电化学活性的壳聚糖水凝胶的制备方法 |
KR101916193B1 (ko) * | 2016-08-25 | 2018-11-07 | 주식회사 파마리서치프로덕트 | 핵산 및 키토산을 포함하는 관절강 주사용 조성물 |
WO2018128704A2 (en) | 2016-11-07 | 2018-07-12 | 3M Innovative Properties Company | Medical composition containing guanidinyl-containing polymer(s) and carrageenane(s) |
WO2018119320A1 (en) * | 2016-12-21 | 2018-06-28 | Cresilon, Inc. | Hemostatic compositions with antifibrinolytic agents |
IL249725A0 (en) | 2016-12-22 | 2017-03-30 | Omrix Biopharmaceuticals Ltd | A hemostatic preparation containing an anion exchanger and a calcium salt |
KR102519771B1 (ko) * | 2016-12-22 | 2023-04-10 | 옴릭스 바이오파머슈티컬스 리미티드 | 음이온 교환제 및 칼슘 염을 포함하는 지혈 조성물 |
JP6939607B2 (ja) * | 2017-03-27 | 2021-09-22 | Jsr株式会社 | 組成物およびその用途 |
CN108926490B (zh) * | 2017-05-25 | 2021-01-26 | 南方医科大学南方医院 | 一种抗凝胃管的制作方法 |
KR102218427B1 (ko) * | 2017-09-20 | 2021-02-22 | 차의과학대학교 산학협력단 | 단백질 약물을 포함하는 코아세르베이트 조성물 및 이를 포함하는 창상 치료제 |
JP7410876B2 (ja) | 2018-01-26 | 2024-01-10 | フルイデックス メディカル テクノロジー,リミティッド ライアビリティ カンパニー | 血管閉塞のためにその場凝固複合コアセルベートを使用する装置及び方法 |
AU2019212970A1 (en) * | 2018-01-26 | 2020-06-18 | Polarityte, Inc. | Composite-interfacing biomaterial accelerant substrate |
RU2675631C1 (ru) * | 2018-10-02 | 2018-12-21 | Общество с ограниченной ответственностью "Новые Биомедицинские Решения" | Местное гемостатическое средство с повышенной антимикробной активностью |
EP3946480A1 (en) * | 2019-04-03 | 2022-02-09 | DTech - Società a Responsabilità Limitata | Two-component system for the therapeutic treatment of skin lesions and production method thereof |
CN110157010B (zh) * | 2019-05-05 | 2021-04-02 | 上海交通大学 | 一种基于多糖/聚肽的聚电解质复合物水凝胶止血剂 |
CN111303453B (zh) * | 2020-03-09 | 2021-06-04 | 中国海洋大学 | 一种多重敏感型水凝胶聚合物的制备方法和应用 |
EP3925636A1 (en) | 2020-06-17 | 2021-12-22 | Centre Of Experimental Medicine Slovak Academy Of Sciences Institute Of Experimental Pharmacology | Composite membranes containing a smart-released cytoprotectant targeting the inflamed tissue and use thereof |
CN115887738B (zh) * | 2022-12-16 | 2024-05-10 | 湖南师范大学 | 一种聚丙烯酰胺-壳聚糖/高岭土多孔材料及其制备方法 |
Family Cites Families (66)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS58206751A (ja) | 1982-05-26 | 1983-12-02 | 日石三菱株式会社 | 創傷被覆材 |
JPS59139310A (ja) | 1983-01-31 | 1984-08-10 | Shiseido Co Ltd | 乳化組成物 |
JPH0612993B2 (ja) | 1987-08-10 | 1994-02-23 | 株式会社クラレ | 球状の微生物固定化成形物の製造法 |
US4956350A (en) * | 1988-08-18 | 1990-09-11 | Minnesota Mining And Manufacturing Company | Wound filling compositions |
FI95207C (fi) | 1992-09-14 | 1996-01-10 | Novasso Oy | Haavansuojaside |
JP3411602B2 (ja) * | 1992-10-22 | 2003-06-03 | グンゼ株式会社 | キトサンの溶解方法 |
DE4337152A1 (de) * | 1993-10-30 | 1995-05-04 | Merck Patent Gmbh | Verfahren zur Herstellung von wäßrigen Chitosan-Lösungen und -Gelen |
US5670169A (en) | 1993-12-20 | 1997-09-23 | E.R. Squibb & Sons, Inc. | Wound hydrating gel with novel preservative system and low cytotoxicity |
US20020032488A1 (en) | 1994-05-13 | 2002-03-14 | Brekke John H. | Device for regeneration of articular cartilage and other tissue |
US6150581A (en) * | 1995-06-07 | 2000-11-21 | United States Surgical Corporation | Chitosan/alginate anti-adhesion barrier |
US5836970A (en) * | 1996-08-02 | 1998-11-17 | The Kendall Company | Hemostatic wound dressing |
GB2328443B (en) * | 1997-08-21 | 2001-09-05 | Reckitt & Colmann Prod Ltd | In situ formation of pharmaceutically acceptable polymeric material |
JP2002500169A (ja) | 1998-01-06 | 2002-01-08 | セウサ,ニコラス・エイ | テオレル−マイヤー勾配に基づく薬投与形 |
US6200595B1 (en) | 1998-04-24 | 2001-03-13 | Kuraray Co., Ltd. | Medical adhesive |
JP4241985B2 (ja) | 1998-04-24 | 2009-03-18 | 株式会社クラレ | 医療用接着材 |
JPH11318407A (ja) * | 1998-05-19 | 1999-11-24 | Lion Corp | 加工食品 |
AU5279299A (en) | 1998-08-31 | 2000-03-21 | Coloplast A/S | A composition capable of absorbing fluid |
JP4267106B2 (ja) * | 1998-10-15 | 2009-05-27 | 株式会社クラレ | 癒着防止用材料 |
JP4159682B2 (ja) * | 1998-12-22 | 2008-10-01 | 株式会社クラレ | 止血材 |
JP4149098B2 (ja) | 1999-09-13 | 2008-09-10 | 株式会社クラレ | 水膨潤性医療用高分子ゲルの製造法及び水膨潤性医療用高分子ゲル |
US20030206958A1 (en) | 2000-12-22 | 2003-11-06 | Cattaneo Maurizio V. | Chitosan biopolymer for the topical delivery of active agents |
CA2476653C (en) * | 2002-02-21 | 2009-01-27 | Encelle, Inc. | Cross-linked bioactive hydrogel matrices |
US7217426B1 (en) * | 2002-06-21 | 2007-05-15 | Advanced Cardiovascular Systems, Inc. | Coatings containing polycationic peptides for cardiovascular therapy |
JP2004041586A (ja) | 2002-07-15 | 2004-02-12 | Fujimori Kogyo Co Ltd | 生体適合性材料およびその製造方法 |
US7112713B2 (en) | 2003-03-12 | 2006-09-26 | Gelsus Research And Consulting, Inc. | Dressing based on the Teorell-Meyer gradient |
US7641643B2 (en) | 2003-04-15 | 2010-01-05 | Abbott Cardiovascular Systems Inc. | Methods and compositions to treat myocardial conditions |
CA2557042C (en) * | 2004-02-23 | 2013-06-25 | Loma Linda University Medical Center | Hemostatic agent for topical and internal use |
CA2559075A1 (en) | 2004-03-11 | 2005-09-22 | Medtrade Products Limited | Compositions of alpha and beta chitosan and methods of preparing them |
WO2006005340A1 (en) * | 2004-07-09 | 2006-01-19 | Ferrosan A/S | Haemostatic composition comprising hyaluronic acid |
EP1799192A2 (en) * | 2004-07-22 | 2007-06-27 | Allan D. Pronovost | Compositions and methods for treating excessive bleeding |
RU2403069C2 (ru) * | 2005-07-21 | 2010-11-10 | ФМС БиоПолимер АС | Медицинские устройства, покрытые быстро растворяющимся биосовместимым покрытием |
US20070110813A1 (en) * | 2005-11-02 | 2007-05-17 | Aeris Therapeutics, Inc. | Polycation-polyanion complexes, compositions and methods of use thereof |
CN100411690C (zh) * | 2006-01-17 | 2008-08-20 | 武汉理工大学 | 一种抑菌聚电解质多孔材料的制备方法 |
WO2007112446A2 (en) | 2006-03-28 | 2007-10-04 | University Of Washington | Alginate-based nanofibers and related scaffolds |
US20070237811A1 (en) * | 2006-04-10 | 2007-10-11 | Scherr George H | Chitosan wound dressing |
ITPD20060203A1 (it) * | 2006-05-22 | 2007-11-23 | Univ Degli Studi Trieste | Idrogeli di miscele di polisaccaridi per l'ingegneria tissutale e la veicolazione di composti attivi |
CN1883721A (zh) * | 2006-06-21 | 2006-12-27 | 哈尔滨工业大学 | 共价交联凝胶改性人工植入体的方法 |
US7935363B2 (en) * | 2006-12-12 | 2011-05-03 | Synthasome, Inc. | Composite material for tissue repair |
NZ616957A (en) | 2007-02-19 | 2015-06-26 | Marinepolymer Tech Inc | Hemostatic compositions and therapeutic regimens |
US8216506B2 (en) | 2007-06-11 | 2012-07-10 | National University Corporation Kyoto Institute Of Technology | Method of processing plant |
US20090041858A1 (en) | 2007-08-06 | 2009-02-12 | Cao Group, Inc. | Haemostatic Compositions Thickened by Polymers Containing Nitrogen Moieties |
AU2008293135B2 (en) * | 2007-08-28 | 2014-08-07 | Adelaide Research & Innovation Pty Ltd | Surgical hydrogel |
US20090123509A1 (en) | 2007-11-08 | 2009-05-14 | Cory Berkland | Biodegradable Colloidal Gels as Moldable Tissue Engineering Scaffolds |
US8283384B2 (en) * | 2008-01-24 | 2012-10-09 | University Of Utah Research Foundation | Adhesive complex coacervates and methods of making and using thereof |
WO2009132228A1 (en) * | 2008-04-24 | 2009-10-29 | Medtronic, Inc. | Chitosan-containing protective composition |
WO2010022132A2 (en) * | 2008-08-19 | 2010-02-25 | The Regents Of The University Of Michigan | Biocompatible coatings, and methods of making and using the same |
CN101463145A (zh) * | 2009-01-12 | 2009-06-24 | 武汉理工大学 | 羧甲基壳聚糖/氧化海藻酸钠自交联抗菌水凝胶材料 |
CN101463144B (zh) * | 2009-01-12 | 2010-12-29 | 武汉理工大学 | 羟丙基壳聚糖/氧化海藻酸钠自交联抗菌水凝胶材料的制备方法 |
EP2416741B1 (en) | 2009-04-06 | 2015-03-11 | Bender Analytical Holding B.V. | In situ gelling alginate systems |
KR101103423B1 (ko) * | 2009-09-04 | 2012-01-06 | 아주대학교산학협력단 | 생체 주입형 조직 접착성 하이드로젤 및 이의 생의학적 용도 |
EP2504039A4 (en) | 2009-11-25 | 2014-07-02 | Univ Loma Linda Med | HEMOSTATIC TEXTILE BASED ON CHITOSAN |
EP2512588A4 (en) * | 2009-12-16 | 2014-06-04 | Univ Columbia | METHODS, DEVICES, AND SYSTEMS FOR DELIVERY OF ULTRASOUND-DEMARTED MEDICATION |
US8389498B2 (en) | 2010-03-26 | 2013-03-05 | Taiwan Textile Research Institute | Spinning solution and method for manufacturing biomaterial fibers |
US8968362B2 (en) | 2010-04-08 | 2015-03-03 | Covidien Lp | Coated looped suture |
US20110287067A1 (en) * | 2010-05-24 | 2011-11-24 | University Of Utah Research Foundation | Reinforced adhesive complex coacervates and methods of making and using thereof |
AU2011287215B2 (en) * | 2010-08-05 | 2015-09-10 | Lifebond Ltd. | Dry composition wound dressings and adhesives |
CN102475691B (zh) | 2010-11-30 | 2014-04-16 | 中国科学院大连化学物理研究所 | 海藻酸盐-壳聚糖酰基衍生物微胶囊及其制备和应用 |
KR101967005B1 (ko) | 2011-03-17 | 2019-04-08 | 퍼마-픽스 인바이런멘틀 서비시스, 인크. | 키토산계 미세다공성 복합물질의 제조 및 이의 응용 |
PL2626092T3 (pl) | 2011-04-01 | 2016-02-29 | Zhuhai Ortus Biotechnology Co Ltd | Medyczny wchłanialny hemostatyczny materiał do ran z obnażeniem kości i sposób jego wytwarzania |
GB2499359B (en) | 2011-10-05 | 2016-12-28 | Univ Of Bolton | Polysaccharide fibres for wound dressings |
CA2855347C (en) | 2011-11-13 | 2019-03-05 | Suneris Inc. | In-situ cross-linkable polymeric compositions and methods thereof |
US8895304B2 (en) | 2011-12-09 | 2014-11-25 | Acell, Inc. | Hemostatic device |
AU2013356930B2 (en) | 2012-12-10 | 2017-01-05 | Regenics As | Use of egg cellular extracts for skin rejuvenation |
US10918765B2 (en) | 2013-04-11 | 2021-02-16 | University Of Vermont And State Agricultural College | Decellularization and recellularization of whole organs |
CN107614875B (zh) | 2015-06-11 | 2019-08-20 | 株式会社村田制作所 | 泵 |
BR112017027625A2 (pt) | 2015-06-22 | 2018-08-28 | Cresilon, Inc. | matriz polimérica adesiva hemostática altamente eficaz |
-
2012
- 2012-11-12 CA CA2855347A patent/CA2855347C/en active Active
- 2012-11-12 SG SG10201610469QA patent/SG10201610469QA/en unknown
- 2012-11-12 RU RU2017144044A patent/RU2017144044A/ru not_active Application Discontinuation
- 2012-11-12 MX MX2014005738A patent/MX366366B/es active IP Right Grant
- 2012-11-12 CN CN201280055699.0A patent/CN103930133A/zh active Pending
- 2012-11-12 BR BR112014011442A patent/BR112014011442A8/pt not_active Application Discontinuation
- 2012-11-12 EP EP12848403.7A patent/EP2776068A4/en not_active Withdrawn
- 2012-11-12 SG SG11201402279SA patent/SG11201402279SA/en unknown
- 2012-11-12 US US14/357,342 patent/US20140287061A1/en not_active Abandoned
- 2012-11-12 RU RU2014124157A patent/RU2640084C2/ru active
- 2012-11-12 AU AU2012334982A patent/AU2012334982A1/en not_active Abandoned
- 2012-11-12 WO PCT/US2012/064670 patent/WO2013071235A1/en active Application Filing
- 2012-11-12 IN IN3524CHN2014 patent/IN2014CN03524A/en unknown
- 2012-11-12 KR KR1020147015600A patent/KR20140090670A/ko not_active Application Discontinuation
- 2012-11-12 JP JP2014541368A patent/JP2014533181A/ja active Pending
- 2012-11-12 CN CN201811325132.6A patent/CN109602944A/zh active Pending
-
2014
- 2014-04-29 IL IL232330A patent/IL232330B/en active IP Right Grant
- 2014-05-02 ZA ZA2014/03166A patent/ZA201403166B/en unknown
- 2014-05-12 MX MX2019008051A patent/MX2019008051A/es unknown
-
2015
- 2015-03-06 HK HK15102296.0A patent/HK1201734A1/xx unknown
-
2016
- 2016-09-15 US US15/266,813 patent/US9687584B1/en active Active
-
2017
- 2017-06-01 US US15/611,418 patent/US10850003B2/en active Active
- 2017-08-23 AU AU2017219007A patent/AU2017219007A1/en not_active Abandoned
-
2018
- 2018-06-26 JP JP2018120864A patent/JP7013336B2/ja active Active
-
2020
- 2020-09-14 JP JP2020153716A patent/JP2021007754A/ja not_active Withdrawn
- 2020-10-29 US US17/084,518 patent/US11383005B2/en active Active
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
MX2019008051A (es) | Composiciones polimericas reticulables in-situ y metodos de las mismas. | |
WO2013061309A3 (en) | New a-prp medical device & tissue engineering composition, manufacturing machines and process | |
WO2014152796A3 (en) | Biocompatible and bioabsorbable derivatized chitosan compositions | |
WO2012008722A3 (ko) | 조직 증강용 충전 조성물 | |
WO2009015255A3 (en) | Composition and method for improving retention and drainage in papermaking processes by activating microparticles with a promoter-flocculant system | |
EP2287206A4 (en) | POLYROTAXANE, AQUEOUS POLYROTAXANEVISION COMPOSITION, NETWORKED POLYROTAXAN AND POLYMERIC BODY AND METHOD OF PRODUCTION THEREOF | |
EP2578622A3 (en) | Enhanced oilfield swellable elastomers and methods for making and using same | |
GB201020193D0 (en) | Glucan compositions | |
WO2013060769A3 (en) | Hemostatic compositions | |
MX2010004836A (es) | Composicion de quitosan. | |
WO2014093489A3 (en) | Hydrogel membrane for adhesion prevention | |
MX2016007534A (es) | Composicion de gel de acido hialuronico que tiene durabilidad. | |
WO2018056937A3 (en) | Nanofibrous adhesion barrier | |
EP2395048A3 (en) | Polymers compositions including an antioxidant | |
EP2488023A4 (en) | ANTIMICROBIAL COMPOSITION | |
BRPI1011188A2 (pt) | composições de liberação dérmica compreendendo complexos de partículas de agente ativo-fosfato de cálcio e métodos para usar as mesmas. | |
WO2011126839A3 (en) | Compositions and methods for improved retention of a pharmaceutical composition at a local administration site | |
WO2007144644A3 (en) | Extracellular matrix composition | |
WO2015091885A3 (en) | Microcapsules with polymeric coating comprising a lipid and an active agent | |
NZ603479A (en) | Chitosan composition | |
MX2017014464A (es) | Composicion reticulante que incluye silicato sintetico en capas. | |
BR112013025495A2 (pt) | massa óssea | |
WO2012115748A3 (en) | Corn fiber gum composites as a thickener | |
UA114534C2 (uk) | Бітумна композиція у формі гранул та спосіб її одержання | |
MY179975A (en) | Use of a 2-octyl acrylate polymer as a binding agent in a coating composition |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
HC | Change of company name or juridical status |
Owner name: NOXELL CORPORATION |
|
FG | Grant or registration |