SG10201610469QA - In-situ cross-linkable polymeric compositions and methods thereof - Google Patents

In-situ cross-linkable polymeric compositions and methods thereof

Info

Publication number
SG10201610469QA
SG10201610469QA SG10201610469QA SG10201610469QA SG10201610469QA SG 10201610469Q A SG10201610469Q A SG 10201610469QA SG 10201610469Q A SG10201610469Q A SG 10201610469QA SG 10201610469Q A SG10201610469Q A SG 10201610469QA SG 10201610469Q A SG10201610469Q A SG 10201610469QA
Authority
SG
Singapore
Prior art keywords
methods
polymeric compositions
situ cross
linkable polymeric
linkable
Prior art date
Application number
SG10201610469QA
Inventor
Joseph A Landolina
Original Assignee
Cresilon Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cresilon Inc filed Critical Cresilon Inc
Publication of SG10201610469QA publication Critical patent/SG10201610469QA/en

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0009Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
    • A61L26/0052Mixtures of macromolecular compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/22Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/001Use of materials characterised by their function or physical properties
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0009Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
    • A61L26/0014Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0009Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
    • A61L26/0023Polysaccharides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0061Use of materials characterised by their function or physical properties
    • A61L26/0066Medicaments; Biocides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F283/00Macromolecular compounds obtained by polymerising monomers on to polymers provided for in subclass C08G
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L5/00Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
    • C08L5/04Alginic acid; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00Materials characterised by their function or physical properties
    • A61L2400/04Materials for stopping bleeding
SG10201610469QA 2011-11-13 2012-11-12 In-situ cross-linkable polymeric compositions and methods thereof SG10201610469QA (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201161559110P 2011-11-13 2011-11-13

Publications (1)

Publication Number Publication Date
SG10201610469QA true SG10201610469QA (en) 2017-02-27

Family

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Family Applications (2)

Application Number Title Priority Date Filing Date
SG10201610469QA SG10201610469QA (en) 2011-11-13 2012-11-12 In-situ cross-linkable polymeric compositions and methods thereof
SG11201402279SA SG11201402279SA (en) 2011-11-13 2012-11-12 In-situ cross-linkable polymeric compositions and methods thereof

Family Applications After (1)

Application Number Title Priority Date Filing Date
SG11201402279SA SG11201402279SA (en) 2011-11-13 2012-11-12 In-situ cross-linkable polymeric compositions and methods thereof

Country Status (16)

Country Link
US (4) US20140287061A1 (en)
EP (1) EP2776068A4 (en)
JP (3) JP2014533181A (en)
KR (1) KR20140090670A (en)
CN (2) CN103930133A (en)
AU (2) AU2012334982A1 (en)
BR (1) BR112014011442A8 (en)
CA (1) CA2855347C (en)
HK (1) HK1201734A1 (en)
IL (1) IL232330B (en)
IN (1) IN2014CN03524A (en)
MX (2) MX366366B (en)
RU (2) RU2017144044A (en)
SG (2) SG10201610469QA (en)
WO (1) WO2013071235A1 (en)
ZA (1) ZA201403166B (en)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9272069B2 (en) 2008-01-24 2016-03-01 University Of Utah Research Foundation Adhesive complex coacervates and methods of making and using thereof
US8283384B2 (en) 2008-01-24 2012-10-09 University Of Utah Research Foundation Adhesive complex coacervates and methods of making and using thereof
CN103025360A (en) 2010-05-24 2013-04-03 犹他大学研究基金会 Reinforced adhesive complex coacervates and methods of making and using thereof
JP2014502296A (en) 2010-11-12 2014-01-30 ユニバーシティ・オブ・ユタ・リサーチ・ファウンデイション Simple adhesive coacervate and its production method and use
US20140287061A1 (en) 2011-11-13 2014-09-25 Suneris, Inc. In-situ cross-linkable polymeric compositions and methods thereof
EP2953992B1 (en) 2013-02-06 2021-11-24 3M Innovative Properties Company Polymers, preparation and use thereof
ITTO20130375A1 (en) * 2013-05-10 2014-11-11 Marco Benzi PRODUCT FOR USE FOR THERAPEUTIC TREATMENT OF PARODONTOPATHIES AND PERIMPLANTS
CN103611180B (en) * 2013-11-21 2015-02-18 无锡中科光远生物材料有限公司 Preparation method of self-adhesion hemostasis anti-adhesion corpus fibrosum
DK3166550T3 (en) 2014-07-11 2024-01-29 Us Health Surgical tool for ocular tissue transplantation
EP3632478B1 (en) 2014-07-14 2022-09-28 University of Utah Research Foundation In situ solidifying solution and methods of making and using thereof
RU2750648C2 (en) * 2015-06-22 2021-06-30 Кресилон, Инк. High-efficiency haemostatic adhesive polymer frame
US10660945B2 (en) 2015-08-07 2020-05-26 Victor Matthew Phillips Flowable hemostatic gel composition and its methods of use
US10751444B2 (en) 2015-08-07 2020-08-25 Victor Matthew Phillips Flowable hemostatic gel composition and its methods of use
CN105030815B (en) * 2015-08-10 2019-03-15 贵州扬生医用器材有限公司 A kind of surgical flush fluid and its preparation method
WO2017106333A1 (en) 2015-12-14 2017-06-22 University Of Pittsburgh-Of The Commonwealth System Of Higher Education Complex coacervate for controlled release and related methods
KR101666792B1 (en) 2016-02-05 2016-10-17 주식회사 파마리서치프로덕트 Thermosensitive hydrogel composition containing nucleic acid and chitosan
US11298423B2 (en) * 2016-03-04 2022-04-12 University of Pittsburgh—of the Commonwealth System of Higher Education Protection and delivery of multiple therapeutic proteins
CN105860107B (en) * 2016-04-26 2018-02-09 中南大学 A kind of hydrogen peroxide response and the preparation method of the aquagel with electro-chemical activity
KR101916193B1 (en) * 2016-08-25 2018-11-07 주식회사 파마리서치프로덕트 Injectable composition comprising nucleic acid and chitosan for articular cavity
EP3534867A2 (en) 2016-11-07 2019-09-11 3M Innovative Properties Company Medical composition containing guanidinyl-containing polymer(s) and carrageenane(s)
WO2018119320A1 (en) * 2016-12-21 2018-06-28 Cresilon, Inc. Hemostatic compositions with antifibrinolytic agents
IL249725A0 (en) 2016-12-22 2017-03-30 Omrix Biopharmaceuticals Ltd Hemostatic composition comprising an anion exchanger and a calcium salt
IL267432B1 (en) * 2016-12-22 2024-03-01 Omrix Biopharmaceuticals Ltd Hemostatic composition comprising an anion exchanger and a calcium salt
JP6939607B2 (en) * 2017-03-27 2021-09-22 Jsr株式会社 Compositions and their uses
CN108926490B (en) * 2017-05-25 2021-01-26 南方医科大学南方医院 Manufacturing method of anticoagulation stomach tube
KR102218427B1 (en) 2017-09-20 2021-02-22 차의과학대학교 산학협력단 Coacervate composition comprising protein drug and wound healing agent comprising the same
AU2019212513A1 (en) 2018-01-26 2020-09-03 Fluidx Medical Technology, Llc Apparatus and method of using in situ solidifying complex coacervates for vascular occlusion
AU2019212970A1 (en) * 2018-01-26 2020-06-18 Polarityte, Inc. Composite-interfacing biomaterial accelerant substrate
RU2675631C1 (en) * 2018-10-02 2018-12-21 Общество с ограниченной ответственностью "Новые Биомедицинские Решения" Local hemostatic agent with enhanced antimicrobial activity
US20220211902A1 (en) * 2019-04-03 2022-07-07 Dtech - Società A Responsabilità Limitata Two-component system for the therapeutic treatment of skin lesions and production method thereof
CN110157010B (en) * 2019-05-05 2021-04-02 上海交通大学 Polyelectrolyte complex hydrogel hemostatic based on polysaccharide/polypeptide
JP2020078729A (en) * 2020-03-04 2020-05-28 クレシロン, インコーポレイテッド Highly efficacious hemostatic adhesive polymer scaffold
CN111303453B (en) * 2020-03-09 2021-06-04 中国海洋大学 Preparation method and application of multiple sensitive hydrogel polymer
EP3925636A1 (en) 2020-06-17 2021-12-22 Centre Of Experimental Medicine Slovak Academy Of Sciences Institute Of Experimental Pharmacology Composite membranes containing a smart-released cytoprotectant targeting the inflamed tissue and use thereof
CN115887738A (en) * 2022-12-16 2023-04-04 湖南师范大学 Polyacrylamide-chitosan/kaolin porous material and preparation method thereof

Family Cites Families (66)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58206751A (en) 1982-05-26 1983-12-02 日石三菱株式会社 Wound covering material
JPS59139310A (en) 1983-01-31 1984-08-10 Shiseido Co Ltd Emulsified composition
JPH0612993B2 (en) 1987-08-10 1994-02-23 株式会社クラレ Method for producing spherical microbe-immobilized moldings
US4956350A (en) * 1988-08-18 1990-09-11 Minnesota Mining And Manufacturing Company Wound filling compositions
FI95207C (en) 1992-09-14 1996-01-10 Novasso Oy Wound Protective Side
JP3411602B2 (en) * 1992-10-22 2003-06-03 グンゼ株式会社 Chitosan dissolution method
DE4337152A1 (en) 1993-10-30 1995-05-04 Merck Patent Gmbh Process for the preparation of aqueous chitosan solutions and gels
US5670169A (en) 1993-12-20 1997-09-23 E.R. Squibb & Sons, Inc. Wound hydrating gel with novel preservative system and low cytotoxicity
US20020032488A1 (en) 1994-05-13 2002-03-14 Brekke John H. Device for regeneration of articular cartilage and other tissue
US6150581A (en) * 1995-06-07 2000-11-21 United States Surgical Corporation Chitosan/alginate anti-adhesion barrier
US5836970A (en) * 1996-08-02 1998-11-17 The Kendall Company Hemostatic wound dressing
GB2328443B (en) * 1997-08-21 2001-09-05 Reckitt & Colmann Prod Ltd In situ formation of pharmaceutically acceptable polymeric material
JP2002500169A (en) 1998-01-06 2002-01-08 セウサ,ニコラス・エイ Drug dosage form based on the Teorer-Meier gradient
US6200595B1 (en) 1998-04-24 2001-03-13 Kuraray Co., Ltd. Medical adhesive
JP4241985B2 (en) 1998-04-24 2009-03-18 株式会社クラレ Medical adhesive
JPH11318407A (en) * 1998-05-19 1999-11-24 Lion Corp Processed food
WO2000012144A1 (en) 1998-08-31 2000-03-09 Coloplast A/S A composition capable of absorbing fluid
JP4267106B2 (en) * 1998-10-15 2009-05-27 株式会社クラレ Anti-adhesion material
JP4159682B2 (en) * 1998-12-22 2008-10-01 株式会社クラレ Hemostatic material
JP4149098B2 (en) 1999-09-13 2008-09-10 株式会社クラレ Process for producing water-swellable medical polymer gel and water-swellable medical polymer gel
US20030206958A1 (en) 2000-12-22 2003-11-06 Cattaneo Maurizio V. Chitosan biopolymer for the topical delivery of active agents
ES2318115T3 (en) * 2002-02-21 2009-05-01 Encelle, Inc. BIOACTIVE RETICULATED HYDROGEL MATRICES.
US7217426B1 (en) * 2002-06-21 2007-05-15 Advanced Cardiovascular Systems, Inc. Coatings containing polycationic peptides for cardiovascular therapy
JP2004041586A (en) 2002-07-15 2004-02-12 Fujimori Kogyo Co Ltd Biocompatible material and production method used for the same
US7112713B2 (en) 2003-03-12 2006-09-26 Gelsus Research And Consulting, Inc. Dressing based on the Teorell-Meyer gradient
US8383158B2 (en) 2003-04-15 2013-02-26 Abbott Cardiovascular Systems Inc. Methods and compositions to treat myocardial conditions
AU2005216094B2 (en) * 2004-02-23 2010-12-23 Loma Linda University Medical Center Hemostatic agent for topical and internal use
AU2005221699A1 (en) 2004-03-11 2005-09-22 Medtrade Products Limited Compositions of alpha and beta chitosan and methods of preparing them
KR20070046093A (en) * 2004-07-09 2007-05-02 훼로산 아크티에 셀스카브 Haemostatic composition comprising hyaluronic acid
MX2007000918A (en) * 2004-07-22 2007-12-04 Hemo Nanoscience Llc Compositions and methods for treating excessive bleeding.
CA2615607A1 (en) * 2005-07-21 2007-02-08 Fmc Biopolymer As Medical devices coated with a fast dissolving biocompatible coating
US20070110813A1 (en) * 2005-11-02 2007-05-17 Aeris Therapeutics, Inc. Polycation-polyanion complexes, compositions and methods of use thereof
CN100411690C (en) * 2006-01-17 2008-08-20 武汉理工大学 Bacteriostatic porous polyelectrolyte material and its prepn process
WO2007112446A2 (en) 2006-03-28 2007-10-04 University Of Washington Alginate-based nanofibers and related scaffolds
US20070237811A1 (en) * 2006-04-10 2007-10-11 Scherr George H Chitosan wound dressing
ITPD20060203A1 (en) * 2006-05-22 2007-11-23 Univ Degli Studi Trieste HYDROGELS OF POLYSACCHARID MIXTURES FOR TISSUE ENGINEERING AND THE VEHICLE OF ACTIVE COMPOUNDS
CN1883721A (en) * 2006-06-21 2006-12-27 哈尔滨工业大学 Method for modifying artificial implanter by covalent cross-linking gel
US7935363B2 (en) * 2006-12-12 2011-05-03 Synthasome, Inc. Composite material for tissue repair
ES2621018T3 (en) 2007-02-19 2017-06-30 Marine Polymer Technologies, Inc. Hemostatic compositions and therapeutic regimens
CA2691106C (en) 2007-06-11 2014-11-18 National University Corporation Kyoto Institute Of Technology Method of processing plant
US20090041858A1 (en) 2007-08-06 2009-02-12 Cao Group, Inc. Haemostatic Compositions Thickened by Polymers Containing Nitrogen Moieties
DK2195039T3 (en) * 2007-08-28 2017-01-30 Otago Innovation Ltd SURGICAL HYDROGEL
US20090123509A1 (en) 2007-11-08 2009-05-14 Cory Berkland Biodegradable Colloidal Gels as Moldable Tissue Engineering Scaffolds
US8283384B2 (en) * 2008-01-24 2012-10-09 University Of Utah Research Foundation Adhesive complex coacervates and methods of making and using thereof
WO2009132228A1 (en) * 2008-04-24 2009-10-29 Medtronic, Inc. Chitosan-containing protective composition
US8697771B2 (en) * 2008-08-19 2014-04-15 The Regents Of The University Of Michigan Biocompatible coatings, and methods of making and using the same
CN101463145A (en) * 2009-01-12 2009-06-24 武汉理工大学 Carboxymethyl chitosan / oxidized sodium alginate self-crosslinking antibacterial hydrogel material
CN101463144B (en) * 2009-01-12 2010-12-29 武汉理工大学 Preparation method of hydroxypropyl chitosan / oxidized sodium alginate self-crosslinking antibacterial hydrogel material
EP2416741B1 (en) 2009-04-06 2015-03-11 Bender Analytical Holding B.V. In situ gelling alginate systems
KR101103423B1 (en) * 2009-09-04 2012-01-06 아주대학교산학협력단 In situ forming hydrogel for tissue adhesives and biomedical use thereof
US8623274B2 (en) 2009-11-25 2014-01-07 Loma Linda University Medical Center Chitosan-based hemostatic textile
EP2512588A4 (en) * 2009-12-16 2014-06-04 Univ Columbia Methods, devices, and systems for on-demand ultrasound-triggered drug delivery
US8389498B2 (en) 2010-03-26 2013-03-05 Taiwan Textile Research Institute Spinning solution and method for manufacturing biomaterial fibers
US8968362B2 (en) 2010-04-08 2015-03-03 Covidien Lp Coated looped suture
CN103025360A (en) * 2010-05-24 2013-04-03 犹他大学研究基金会 Reinforced adhesive complex coacervates and methods of making and using thereof
CN103118713B (en) * 2010-08-05 2016-06-01 生命连结有限公司 Dry composition wound dressing and binding agent
CN102475691B (en) 2010-11-30 2014-04-16 中国科学院大连化学物理研究所 Alginate-chitosan acyl derivative microcapsule, its preparation and application
WO2012125994A2 (en) 2011-03-17 2012-09-20 Perma-Fix Environmental Services, Inc. Preparation of chitosan-based microporous composite material and its applications
EP2626092B1 (en) 2011-04-01 2015-08-05 Zhuhai Ortus Biotechnology Co., Ltd. Medical absorbable hemostatic material for bone wounds and preparation method therefor
GB2499359B (en) 2011-10-05 2016-12-28 Univ Of Bolton Polysaccharide fibres for wound dressings
US20140287061A1 (en) 2011-11-13 2014-09-25 Suneris, Inc. In-situ cross-linkable polymeric compositions and methods thereof
WO2013086153A1 (en) 2011-12-09 2013-06-13 Acell, Inc. Hemostatic device
EP3459522B1 (en) 2012-12-10 2021-02-17 Regenics AS Use of egg cellular extracts for wound treatment
US10918765B2 (en) 2013-04-11 2021-02-16 University Of Vermont And State Agricultural College Decellularization and recellularization of whole organs
WO2016199624A1 (en) 2015-06-11 2016-12-15 株式会社村田製作所 Pump
RU2750648C2 (en) 2015-06-22 2021-06-30 Кресилон, Инк. High-efficiency haemostatic adhesive polymer frame

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SG11201402279SA (en) 2014-06-27
US20170266339A1 (en) 2017-09-21
KR20140090670A (en) 2014-07-17
BR112014011442A8 (en) 2018-01-09
RU2640084C2 (en) 2017-12-26
EP2776068A4 (en) 2015-05-20
US20210290817A1 (en) 2021-09-23
CA2855347C (en) 2019-03-05
AU2017219007A1 (en) 2017-09-07
EP2776068A1 (en) 2014-09-17
CN103930133A (en) 2014-07-16
AU2012334982A1 (en) 2014-05-22
MX366366B (en) 2019-07-05
BR112014011442A2 (en) 2017-05-16
CA2855347A1 (en) 2013-05-16
ZA201403166B (en) 2015-11-25
WO2013071235A1 (en) 2013-05-16
IL232330A0 (en) 2014-06-30
JP2021007754A (en) 2021-01-28
US9687584B1 (en) 2017-06-27
US11383005B2 (en) 2022-07-12
US20140287061A1 (en) 2014-09-25
MX2014005738A (en) 2014-07-09
RU2017144044A (en) 2019-02-15
WO2013071235A9 (en) 2013-07-18
US10850003B2 (en) 2020-12-01
US20170157286A1 (en) 2017-06-08
JP7013336B2 (en) 2022-01-31
IN2014CN03524A (en) 2015-10-09
CN109602944A (en) 2019-04-12
JP2014533181A (en) 2014-12-11
RU2014124157A (en) 2015-12-27
JP2018183611A (en) 2018-11-22
MX2019008051A (en) 2019-09-09
HK1201734A1 (en) 2015-09-11
IL232330B (en) 2019-06-30

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