JP2014520573A5 - - Google Patents
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- Publication number
- JP2014520573A5 JP2014520573A5 JP2014521849A JP2014521849A JP2014520573A5 JP 2014520573 A5 JP2014520573 A5 JP 2014520573A5 JP 2014521849 A JP2014521849 A JP 2014521849A JP 2014521849 A JP2014521849 A JP 2014521849A JP 2014520573 A5 JP2014520573 A5 JP 2014520573A5
- Authority
- JP
- Japan
- Prior art keywords
- epa
- biomass
- fatty acids
- amount
- dha
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000002028 Biomass Substances 0.000 claims 18
- 238000000034 method Methods 0.000 claims 16
- 235000014113 dietary fatty acids Nutrition 0.000 claims 9
- 229930195729 fatty acid Natural products 0.000 claims 9
- 239000000194 fatty acid Substances 0.000 claims 9
- 150000004665 fatty acids Chemical class 0.000 claims 9
- 244000005700 microbiome Species 0.000 claims 7
- 239000003921 oil Substances 0.000 claims 6
- 235000020660 omega-3 fatty acid Nutrition 0.000 claims 6
- 238000000855 fermentation Methods 0.000 claims 3
- 230000004151 fermentation Effects 0.000 claims 3
- 239000008346 aqueous phase Substances 0.000 claims 2
- 239000010779 crude oil Substances 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- 241000233866 Fungi Species 0.000 claims 1
- 241000242583 Scyphozoa Species 0.000 claims 1
- 230000000813 microbial effect Effects 0.000 claims 1
- 229940012843 omega-3 fatty acid Drugs 0.000 claims 1
- 239000006014 omega-3 oil Substances 0.000 claims 1
- 235000020777 polyunsaturated fatty acids Nutrition 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161510464P | 2011-07-21 | 2011-07-21 | |
| US61/510,464 | 2011-07-21 | ||
| PCT/US2012/047728 WO2013013208A2 (en) | 2011-07-21 | 2012-07-20 | Eicosapentaenoic acid-producing microorganisms, fatty acid compositions, and methods of making and uses thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017100780A Division JP2017200480A (ja) | 2011-07-21 | 2017-05-22 | エイコサペンタエン酸生成微生物、脂肪酸組成物、ならびにそれらの作製方法および使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014520573A JP2014520573A (ja) | 2014-08-25 |
| JP2014520573A5 true JP2014520573A5 (enExample) | 2015-06-18 |
| JP6338285B2 JP6338285B2 (ja) | 2018-06-06 |
Family
ID=47558749
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014521849A Active JP6338285B2 (ja) | 2011-07-21 | 2012-07-20 | エイコサペンタエン酸生成微生物、脂肪酸組成物、ならびにそれらの作製方法および使用 |
| JP2017100780A Pending JP2017200480A (ja) | 2011-07-21 | 2017-05-22 | エイコサペンタエン酸生成微生物、脂肪酸組成物、ならびにそれらの作製方法および使用 |
| JP2019202514A Active JP7134938B2 (ja) | 2011-07-21 | 2019-11-07 | エイコサペンタエン酸生成微生物、脂肪酸組成物、ならびにそれらの作製方法および使用 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017100780A Pending JP2017200480A (ja) | 2011-07-21 | 2017-05-22 | エイコサペンタエン酸生成微生物、脂肪酸組成物、ならびにそれらの作製方法および使用 |
| JP2019202514A Active JP7134938B2 (ja) | 2011-07-21 | 2019-11-07 | エイコサペンタエン酸生成微生物、脂肪酸組成物、ならびにそれらの作製方法および使用 |
Country Status (20)
| Country | Link |
|---|---|
| US (5) | US9045785B2 (enExample) |
| EP (4) | EP2734630B1 (enExample) |
| JP (3) | JP6338285B2 (enExample) |
| KR (2) | KR102038715B1 (enExample) |
| CN (3) | CN105255738B (enExample) |
| AR (1) | AR087944A1 (enExample) |
| AU (2) | AU2012285803B2 (enExample) |
| BR (2) | BR122015020130A2 (enExample) |
| CA (1) | CA2842374C (enExample) |
| CL (2) | CL2014000156A1 (enExample) |
| DK (1) | DK3050972T3 (enExample) |
| EA (1) | EA034980B1 (enExample) |
| ES (2) | ES2859752T3 (enExample) |
| IL (1) | IL230500B (enExample) |
| MX (2) | MX385408B (enExample) |
| MY (1) | MY169454A (enExample) |
| PH (1) | PH12014500169B1 (enExample) |
| SG (1) | SG10201605966TA (enExample) |
| WO (1) | WO2013013208A2 (enExample) |
| ZA (2) | ZA201400620B (enExample) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3118954B2 (ja) | 1992-05-14 | 2000-12-18 | 石川島播磨重工業株式会社 | 偏平ブロー成形装置 |
| JP3196316B2 (ja) | 1992-05-20 | 2001-08-06 | 石川島播磨重工業株式会社 | ブロー成形装置 |
| JP3125443B2 (ja) | 1992-07-02 | 2001-01-15 | 石川島播磨重工業株式会社 | 偏平ブロー成形装置 |
| JP3196326B2 (ja) | 1992-06-22 | 2001-08-06 | 石川島播磨重工業株式会社 | 偏平ブロー成形装置 |
| JP3196323B2 (ja) | 1992-06-09 | 2001-08-06 | 石川島播磨重工業株式会社 | 偏平ブロー成形機のパリソン皺矯正装置 |
| CA2993690C (en) * | 2010-01-19 | 2022-03-22 | Dsm Ip Assets B.V. | Eicosapentaenoic acid-producing microorganisms, fatty acid compositions, and methods of making and uses thereof |
| EA035287B1 (ru) | 2011-07-21 | 2020-05-25 | ДСМ АйПи АССЕТС Б.В. | Микроорганизмы, продуцирующие эйкозапентаеновую кислоту, композиции, содержащие жирные кислоты, и способы их получения и применения |
| US9587215B2 (en) | 2014-08-07 | 2017-03-07 | General Electric Company | Devices, systems and methods for automated transfer of a sample |
| CA2958439C (en) | 2014-10-02 | 2022-09-20 | Evonik Industries Ag | Feedstuff of high abrasion resistance and good stability in water, containing pufas |
| DK3200606T3 (da) * | 2014-10-02 | 2021-06-21 | Evonik Operations Gmbh | Fremgangsmåde til fremstilling af et fodermiddel, der indeholder pufa'er, ved ekstrusion af en biomasse, der indeholder pufa'er, af typen labyrinthulomycetes |
| BR112017006838B1 (pt) | 2014-10-02 | 2021-07-06 | Evonik Operations Gmbh | Processo para produzir um alimento para animais compreendendo biomassa contendo pufa, alimento para animais e método para criar animais |
| BR112017005388B1 (pt) | 2014-10-02 | 2022-09-13 | Evonik Operations Gmbh | Alimento para animais contendo biomassa de aurantiochytrium |
| CN106433944A (zh) * | 2015-08-05 | 2017-02-22 | 嘉必优生物技术（武汉）股份有限公司 | 一种富含磷脂型多不饱和脂肪酸的微生物油脂的制备方法 |
| JP6998935B2 (ja) | 2016-07-13 | 2022-01-18 | エボニック オペレーションズ ゲーエムベーハー | 溶解された脂質含有バイオマスから脂質を分離する方法 |
| US20190300818A1 (en) * | 2016-07-13 | 2019-10-03 | Evonik Degussa Gmbh | Method for isolating lipids from lipid-containing cells |
| EP3494093B1 (en) | 2016-08-19 | 2022-05-18 | Noblegen Inc. | Methods and uses of dissolved organic material fractions for binding metal ions |
| ES2872009T3 (es) | 2016-12-27 | 2021-11-02 | Evonik Degussa Gmbh | Método de aislamiento de lípidos a partir de una biomasa que contiene lípidos |
| MX2019011999A (es) | 2017-04-07 | 2019-12-11 | Noblegen Inc | Metodo y usos de exudados encapsulados y biomasa seca de euglena para la union de metal. |
| EP3470502A1 (en) | 2017-10-13 | 2019-04-17 | Evonik Degussa GmbH | Method of separating lipids from a lysed lipids containing biomass |
| EP3527664A1 (en) | 2018-02-15 | 2019-08-21 | Evonik Degussa GmbH | Method of isolating lipids from a lipids containing biomass |
| BR112020023222A2 (pt) | 2018-05-15 | 2021-03-23 | Evonik Operations Gmbh | método de isolamento de lipídios a partir de uma biomassa contendo lipídios lisados por inversão por emulsão |
| RU2760575C1 (ru) | 2018-05-15 | 2021-11-29 | Эвоник Оперейшнс Гмбх | Способ выделения липидов из содержащей липиды биомассы с помощью гидрофобного диоксида кремния |
| US20210277430A1 (en) * | 2020-03-09 | 2021-09-09 | Lanzatech, Inc. | Fermentation process for the production of lipids |
| KR20240141784A (ko) | 2022-01-25 | 2024-09-27 | 디에스엠 아이피 어셋츠 비.브이. | 다중불포화 지방산 생산을 증가시키기 위한 배지 조정 및 영양소 공급 접근법 |
| CN115927005B (zh) * | 2022-10-14 | 2024-11-22 | 广西中医药大学 | 两面针内生真菌y118的固体发酵培养基及其制备和培养方法 |
| WO2025019424A1 (en) * | 2023-07-14 | 2025-01-23 | Dsm Ip Assets B.V. | Microbial oils having high epa content and methods of making the same |
| CN118755584B (zh) * | 2024-08-06 | 2025-04-29 | 杭州合碳创物科技有限公司 | 一种高产epa的裂殖壶菌及其应用 |
Family Cites Families (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6451567B1 (en) * | 1988-09-07 | 2002-09-17 | Omegatech, Inc. | Fermentation process for producing long chain omega-3 fatty acids with euryhaline microorganisms |
| US5130242A (en) | 1988-09-07 | 1992-07-14 | Phycotech, Inc. | Process for the heterotrophic production of microbial products with high concentrations of omega-3 highly unsaturated fatty acids |
| CA2596241C (en) * | 1993-06-09 | 2011-04-19 | Martek Biosciences Corporation | Methods and pharmaceutical compositions useful for treating neurological disorders |
| AU5346296A (en) | 1995-04-17 | 1996-11-07 | Japan As Represented By Director-General Of Agency Of Industrial Science And Technology | Novel microorganisms capable of producing highly unsaturated fatty acids and process for producing highly unsaturated fa tty acids by using the microorganisms |
| US6255505B1 (en) * | 1996-03-28 | 2001-07-03 | Gist-Brocades, B.V. | Microbial polyunsaturated fatty acid containing oil from pasteurised biomass |
| ATE305048T1 (de) | 1997-08-01 | 2005-10-15 | Martek Biosciences Corp | Dha-enthaltende naehrzusammensetzungen und verfahren zu deren herstellung |
| CA2397655C (en) | 2000-01-19 | 2012-06-05 | Craig M. Ruecker | Solventless extraction process |
| CN101519679B (zh) * | 2000-01-28 | 2013-11-13 | Dsmip资产公司 | 通过在发酵罐中高密度培养真核微生物来增加含有多烯脂肪酸的脂质的产生 |
| US6410282B1 (en) * | 2000-03-30 | 2002-06-25 | Council Of Scientific And Industrial Research | Method for enhancing levels of polyunsaturated fatty acids in thraustochytrid fungi |
| DE10102337A1 (de) * | 2001-01-19 | 2002-07-25 | Basf Plant Science Gmbh | Verfahren zur Herstellung mehrfach ungesättigter Fettsäuren, neue Biosynthesegene sowie neue pflanzliche Expressionskonstrukte |
| US20040203120A1 (en) * | 2002-03-22 | 2004-10-14 | Council Of Scientific And Industrial Research | Method for enhancing levels of polyunsaturated fatty acids in thraustochytrid protists |
| JP4280158B2 (ja) | 2002-12-27 | 2009-06-17 | 富士フイルム株式会社 | ドコサヘキサエン酸生産能を有する微生物及びその利用 |
| US20050019880A1 (en) * | 2003-03-31 | 2005-01-27 | Council Of Scientific And Industrial Research | Method of enhancing levels of polyunsaturated fatty acids in thraustochytrid protists |
| EP1706500B1 (en) * | 2003-12-30 | 2010-09-08 | DSM IP Assets B.V. | Deaeration process |
| ES2529572T3 (es) * | 2004-04-22 | 2015-02-23 | Commonwealth Scientific And Industrial Research Organisation | Síntesis de ácidos grasos poliinsaturados de cadena larga por células recombinantes |
| EP2082053B1 (en) | 2006-08-01 | 2016-04-13 | DSM Nutritional Products AG | Process for producing microbial oil comprising polyunsaturated fatty acids |
| KR101650680B1 (ko) * | 2007-08-31 | 2016-08-23 | 디에스엠 아이피 어셋츠 비.브이. | 다중불포화된 지방산 함유 고체 지방 조성물 및 그의 용도 및 생산 |
| EP2203542A1 (en) * | 2007-09-11 | 2010-07-07 | Sapphire Energy, Inc. | Methods of producing organic products with photosynthetic organisms and products and compositions thereof |
| NZ598199A (en) * | 2007-09-12 | 2013-12-20 | Martek Biosciences Corp | Biological oils and production and uses thereof |
| US8323935B2 (en) * | 2007-10-03 | 2012-12-04 | E I Du Pont De Nemours And Company | Optimized strains of Yarrowia lipolytica for high eicosapentaenoic acid production |
| US8207363B2 (en) | 2009-03-19 | 2012-06-26 | Martek Biosciences Corporation | Thraustochytrids, fatty acid compositions, and methods of making and uses thereof |
| EP3926050A1 (en) * | 2009-03-19 | 2021-12-22 | DSM IP Assets B.V. | Thraustochytrids, fatty acid compositions, and methods of making and uses thereof |
| CN103068965A (zh) * | 2009-12-28 | 2013-04-24 | Dsmip资产公司 | 在蔗糖上生长的重组破囊壶菌和其组合物、制备方法及用途 |
| CA2993690C (en) * | 2010-01-19 | 2022-03-22 | Dsm Ip Assets B.V. | Eicosapentaenoic acid-producing microorganisms, fatty acid compositions, and methods of making and uses thereof |
| CN103282474A (zh) * | 2010-04-22 | 2013-09-04 | 纳幕尔杜邦公司 | 从微生物生物质中获得包含多不饱和脂肪酸的组合物的方法 |
| JP5678180B2 (ja) * | 2010-06-09 | 2015-02-25 | フォトンズ コーポレーション リミテッド | 高度精製に適した、エイコサペンタエン酸を含む組成物 |
| ES2857173T3 (es) * | 2011-07-21 | 2021-09-28 | Dsm Ip Assets Bv | Aceites microbianos enriquecidos en ácidos grasos poliinsaturados |
-
2012
- 2012-07-20 CN CN201510526715.5A patent/CN105255738B/zh active Active
- 2012-07-20 EP EP12815192.5A patent/EP2734630B1/en active Active
- 2012-07-20 CN CN202411870122.6A patent/CN119899748A/zh active Pending
- 2012-07-20 AU AU2012285803A patent/AU2012285803B2/en active Active
- 2012-07-20 US US13/554,975 patent/US9045785B2/en active Active
- 2012-07-20 JP JP2014521849A patent/JP6338285B2/ja active Active
- 2012-07-20 SG SG10201605966TA patent/SG10201605966TA/en unknown
- 2012-07-20 EP EP20207686.5A patent/EP3831952A1/en active Pending
- 2012-07-20 BR BR122015020130A patent/BR122015020130A2/pt not_active Application Discontinuation
- 2012-07-20 EA EA201400151A patent/EA034980B1/ru not_active IP Right Cessation
- 2012-07-20 CA CA2842374A patent/CA2842374C/en active Active
- 2012-07-20 AR ARP120102657A patent/AR087944A1/es unknown
- 2012-07-20 PH PH1/2014/500169A patent/PH12014500169B1/en unknown
- 2012-07-20 MX MX2017012687A patent/MX385408B/es unknown
- 2012-07-20 BR BR112014001443-4A patent/BR112014001443B1/pt active IP Right Grant
- 2012-07-20 DK DK15171724.6T patent/DK3050972T3/da active
- 2012-07-20 ES ES15171724T patent/ES2859752T3/es active Active
- 2012-07-20 MY MYPI2014700130A patent/MY169454A/en unknown
- 2012-07-20 KR KR1020147004428A patent/KR102038715B1/ko active Active
- 2012-07-20 MX MX2014000759A patent/MX351174B/es active IP Right Grant
- 2012-07-20 EP EP15171724.6A patent/EP3050972B1/en active Active
- 2012-07-20 WO PCT/US2012/047728 patent/WO2013013208A2/en not_active Ceased
- 2012-07-20 ES ES12815192T patent/ES2774778T3/es active Active
- 2012-07-20 KR KR1020197019037A patent/KR102158437B1/ko active Active
- 2012-07-20 CN CN201280035935.2A patent/CN104011217B/zh active Active
- 2012-07-20 EP EP25170782.4A patent/EP4585049A2/en active Pending
-
2014
- 2014-01-16 IL IL230500A patent/IL230500B/en active IP Right Grant
- 2014-01-21 CL CL2014000156A patent/CL2014000156A1/es unknown
- 2014-01-24 ZA ZA2014/00620A patent/ZA201400620B/en unknown
- 2014-12-10 US US14/566,500 patent/US20150094382A1/en not_active Abandoned
-
2015
- 2015-04-23 ZA ZA2015/02764A patent/ZA201502764B/en unknown
- 2015-04-28 US US14/698,378 patent/US20150223492A1/en not_active Abandoned
- 2015-05-07 CL CL2015001217A patent/CL2015001217A1/es unknown
-
2016
- 2016-11-10 AU AU2016256769A patent/AU2016256769B2/en active Active
-
2017
- 2017-05-18 US US15/598,812 patent/US20170245523A1/en not_active Abandoned
- 2017-05-22 JP JP2017100780A patent/JP2017200480A/ja active Pending
-
2019
- 2019-11-07 JP JP2019202514A patent/JP7134938B2/ja active Active
-
2021
- 2021-11-05 US US17/519,961 patent/US20220322705A1/en active Pending
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