JP6338285B2 - エイコサペンタエン酸生成微生物、脂肪酸組成物、ならびにそれらの作製方法および使用 - Google Patents

エイコサペンタエン酸生成微生物、脂肪酸組成物、ならびにそれらの作製方法および使用 Download PDF

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Publication number
JP6338285B2
JP6338285B2 JP2014521849A JP2014521849A JP6338285B2 JP 6338285 B2 JP6338285 B2 JP 6338285B2 JP 2014521849 A JP2014521849 A JP 2014521849A JP 2014521849 A JP2014521849 A JP 2014521849A JP 6338285 B2 JP6338285 B2 JP 6338285B2
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epa
biomass
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weight
dha
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JP2014520573A (ja
JP2014520573A5 (enExample
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ザ サード, ジョセフ ダブリュー. プファイファー,
ザ サード, ジョセフ ダブリュー. プファイファー,
ジョン ミルトン ハンセン,
ジョン ミルトン ハンセン,
シャオ ダニエル ドン,
シャオ ダニエル ドン,
ポール ウォーレン ベーレンス,
ポール ウォーレン ベーレンス,
カーク イー. アプト,
カーク イー. アプト,
ホセ アール. ガルシア,
ホセ アール. ガルシア,
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DSM IP Assets BV
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    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K10/00Animal feeding-stuffs
    • A23K10/10Animal feeding-stuffs obtained by microbiological or biochemical processes
    • A23K10/16Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/10Organic substances
    • A23K20/158Fatty acids; Fats; Products containing oils or fats
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K50/00Feeding-stuffs specially adapted for particular animals
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K50/00Feeding-stuffs specially adapted for particular animals
    • A23K50/80Feeding-stuffs specially adapted for particular animals for aquatic animals, e.g. fish, crustaceans or molluscs
    • CCHEMISTRY; METALLURGY
    • C11ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11BPRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
    • C11B1/00Production of fats or fatty oils from raw materials
    • C11B1/10Production of fats or fatty oils from raw materials by extracting
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/12Unicellular algae; Culture media therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/12Unicellular algae; Culture media therefor
    • C12N1/125Unicellular algae isolates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/64Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6409Fatty acids
    • C12P7/6427Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone
    • C12P7/6432Eicosapentaenoic acids [EPA]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/89Algae ; Processes using algae

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Food Science & Technology (AREA)
  • Animal Husbandry (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Cell Biology (AREA)
  • Birds (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Botany (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Physiology (AREA)
  • Insects & Arthropods (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
JP2014521849A 2011-07-21 2012-07-20 エイコサペンタエン酸生成微生物、脂肪酸組成物、ならびにそれらの作製方法および使用 Active JP6338285B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161510464P 2011-07-21 2011-07-21
US61/510,464 2011-07-21
PCT/US2012/047728 WO2013013208A2 (en) 2011-07-21 2012-07-20 Eicosapentaenoic acid-producing microorganisms, fatty acid compositions, and methods of making and uses thereof

Related Child Applications (1)

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JP2017100780A Division JP2017200480A (ja) 2011-07-21 2017-05-22 エイコサペンタエン酸生成微生物、脂肪酸組成物、ならびにそれらの作製方法および使用

Publications (3)

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JP2014520573A JP2014520573A (ja) 2014-08-25
JP2014520573A5 JP2014520573A5 (enExample) 2015-06-18
JP6338285B2 true JP6338285B2 (ja) 2018-06-06

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JP2017100780A Pending JP2017200480A (ja) 2011-07-21 2017-05-22 エイコサペンタエン酸生成微生物、脂肪酸組成物、ならびにそれらの作製方法および使用
JP2019202514A Active JP7134938B2 (ja) 2011-07-21 2019-11-07 エイコサペンタエン酸生成微生物、脂肪酸組成物、ならびにそれらの作製方法および使用

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JP2019202514A Active JP7134938B2 (ja) 2011-07-21 2019-11-07 エイコサペンタエン酸生成微生物、脂肪酸組成物、ならびにそれらの作製方法および使用

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US (5) US9045785B2 (enExample)
EP (4) EP2734630B1 (enExample)
JP (3) JP6338285B2 (enExample)
KR (2) KR102038715B1 (enExample)
CN (3) CN105255738B (enExample)
AR (1) AR087944A1 (enExample)
AU (2) AU2012285803B2 (enExample)
BR (2) BR122015020130A2 (enExample)
CA (1) CA2842374C (enExample)
CL (2) CL2014000156A1 (enExample)
DK (1) DK3050972T3 (enExample)
EA (1) EA034980B1 (enExample)
ES (2) ES2859752T3 (enExample)
IL (1) IL230500B (enExample)
MX (2) MX385408B (enExample)
MY (1) MY169454A (enExample)
PH (1) PH12014500169B1 (enExample)
SG (1) SG10201605966TA (enExample)
WO (1) WO2013013208A2 (enExample)
ZA (2) ZA201400620B (enExample)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3118954B2 (ja) 1992-05-14 2000-12-18 石川島播磨重工業株式会社 偏平ブロー成形装置
JP3125443B2 (ja) 1992-07-02 2001-01-15 石川島播磨重工業株式会社 偏平ブロー成形装置
JP3196323B2 (ja) 1992-06-09 2001-08-06 石川島播磨重工業株式会社 偏平ブロー成形機のパリソン皺矯正装置
JP3196316B2 (ja) 1992-05-20 2001-08-06 石川島播磨重工業株式会社 ブロー成形装置
JP3196326B2 (ja) 1992-06-22 2001-08-06 石川島播磨重工業株式会社 偏平ブロー成形装置

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2993690C (en) * 2010-01-19 2022-03-22 Dsm Ip Assets B.V. Eicosapentaenoic acid-producing microorganisms, fatty acid compositions, and methods of making and uses thereof
EA035287B1 (ru) 2011-07-21 2020-05-25 ДСМ АйПи АССЕТС Б.В. Микроорганизмы, продуцирующие эйкозапентаеновую кислоту, композиции, содержащие жирные кислоты, и способы их получения и применения
US9587215B2 (en) 2014-08-07 2017-03-07 General Electric Company Devices, systems and methods for automated transfer of a sample
CA2958439C (en) 2014-10-02 2022-09-20 Evonik Industries Ag Feedstuff of high abrasion resistance and good stability in water, containing pufas
DK3200606T3 (da) * 2014-10-02 2021-06-21 Evonik Operations Gmbh Fremgangsmåde til fremstilling af et fodermiddel, der indeholder pufa'er, ved ekstrusion af en biomasse, der indeholder pufa'er, af typen labyrinthulomycetes
BR112017006838B1 (pt) 2014-10-02 2021-07-06 Evonik Operations Gmbh Processo para produzir um alimento para animais compreendendo biomassa contendo pufa, alimento para animais e método para criar animais
BR112017005388B1 (pt) 2014-10-02 2022-09-13 Evonik Operations Gmbh Alimento para animais contendo biomassa de aurantiochytrium
CN106433944A (zh) * 2015-08-05 2017-02-22 嘉必优生物技术(武汉)股份有限公司 一种富含磷脂型多不饱和脂肪酸的微生物油脂的制备方法
JP6998935B2 (ja) 2016-07-13 2022-01-18 エボニック オペレーションズ ゲーエムベーハー 溶解された脂質含有バイオマスから脂質を分離する方法
US20190300818A1 (en) * 2016-07-13 2019-10-03 Evonik Degussa Gmbh Method for isolating lipids from lipid-containing cells
EP3494093B1 (en) 2016-08-19 2022-05-18 Noblegen Inc. Methods and uses of dissolved organic material fractions for binding metal ions
ES2872009T3 (es) 2016-12-27 2021-11-02 Evonik Degussa Gmbh Método de aislamiento de lípidos a partir de una biomasa que contiene lípidos
MX2019011999A (es) 2017-04-07 2019-12-11 Noblegen Inc Metodo y usos de exudados encapsulados y biomasa seca de euglena para la union de metal.
EP3470502A1 (en) 2017-10-13 2019-04-17 Evonik Degussa GmbH Method of separating lipids from a lysed lipids containing biomass
EP3527664A1 (en) 2018-02-15 2019-08-21 Evonik Degussa GmbH Method of isolating lipids from a lipids containing biomass
BR112020023222A2 (pt) 2018-05-15 2021-03-23 Evonik Operations Gmbh método de isolamento de lipídios a partir de uma biomassa contendo lipídios lisados por inversão por emulsão
RU2760575C1 (ru) 2018-05-15 2021-11-29 Эвоник Оперейшнс Гмбх Способ выделения липидов из содержащей липиды биомассы с помощью гидрофобного диоксида кремния
US20210277430A1 (en) * 2020-03-09 2021-09-09 Lanzatech, Inc. Fermentation process for the production of lipids
KR20240141784A (ko) 2022-01-25 2024-09-27 디에스엠 아이피 어셋츠 비.브이. 다중불포화 지방산 생산을 증가시키기 위한 배지 조정 및 영양소 공급 접근법
CN115927005B (zh) * 2022-10-14 2024-11-22 广西中医药大学 两面针内生真菌y118的固体发酵培养基及其制备和培养方法
WO2025019424A1 (en) * 2023-07-14 2025-01-23 Dsm Ip Assets B.V. Microbial oils having high epa content and methods of making the same
CN118755584B (zh) * 2024-08-06 2025-04-29 杭州合碳创物科技有限公司 一种高产epa的裂殖壶菌及其应用

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6451567B1 (en) * 1988-09-07 2002-09-17 Omegatech, Inc. Fermentation process for producing long chain omega-3 fatty acids with euryhaline microorganisms
US5130242A (en) 1988-09-07 1992-07-14 Phycotech, Inc. Process for the heterotrophic production of microbial products with high concentrations of omega-3 highly unsaturated fatty acids
CA2596241C (en) * 1993-06-09 2011-04-19 Martek Biosciences Corporation Methods and pharmaceutical compositions useful for treating neurological disorders
AU5346296A (en) 1995-04-17 1996-11-07 Japan As Represented By Director-General Of Agency Of Industrial Science And Technology Novel microorganisms capable of producing highly unsaturated fatty acids and process for producing highly unsaturated fa tty acids by using the microorganisms
US6255505B1 (en) * 1996-03-28 2001-07-03 Gist-Brocades, B.V. Microbial polyunsaturated fatty acid containing oil from pasteurised biomass
ATE305048T1 (de) 1997-08-01 2005-10-15 Martek Biosciences Corp Dha-enthaltende naehrzusammensetzungen und verfahren zu deren herstellung
CA2397655C (en) 2000-01-19 2012-06-05 Craig M. Ruecker Solventless extraction process
CN101519679B (zh) * 2000-01-28 2013-11-13 Dsmip资产公司 通过在发酵罐中高密度培养真核微生物来增加含有多烯脂肪酸的脂质的产生
US6410282B1 (en) * 2000-03-30 2002-06-25 Council Of Scientific And Industrial Research Method for enhancing levels of polyunsaturated fatty acids in thraustochytrid fungi
DE10102337A1 (de) * 2001-01-19 2002-07-25 Basf Plant Science Gmbh Verfahren zur Herstellung mehrfach ungesättigter Fettsäuren, neue Biosynthesegene sowie neue pflanzliche Expressionskonstrukte
US20040203120A1 (en) * 2002-03-22 2004-10-14 Council Of Scientific And Industrial Research Method for enhancing levels of polyunsaturated fatty acids in thraustochytrid protists
JP4280158B2 (ja) 2002-12-27 2009-06-17 富士フイルム株式会社 ドコサヘキサエン酸生産能を有する微生物及びその利用
US20050019880A1 (en) * 2003-03-31 2005-01-27 Council Of Scientific And Industrial Research Method of enhancing levels of polyunsaturated fatty acids in thraustochytrid protists
EP1706500B1 (en) * 2003-12-30 2010-09-08 DSM IP Assets B.V. Deaeration process
ES2529572T3 (es) * 2004-04-22 2015-02-23 Commonwealth Scientific And Industrial Research Organisation Síntesis de ácidos grasos poliinsaturados de cadena larga por células recombinantes
EP2082053B1 (en) 2006-08-01 2016-04-13 DSM Nutritional Products AG Process for producing microbial oil comprising polyunsaturated fatty acids
KR101650680B1 (ko) * 2007-08-31 2016-08-23 디에스엠 아이피 어셋츠 비.브이. 다중불포화된 지방산 함유 고체 지방 조성물 및 그의 용도 및 생산
EP2203542A1 (en) * 2007-09-11 2010-07-07 Sapphire Energy, Inc. Methods of producing organic products with photosynthetic organisms and products and compositions thereof
NZ598199A (en) * 2007-09-12 2013-12-20 Martek Biosciences Corp Biological oils and production and uses thereof
US8323935B2 (en) * 2007-10-03 2012-12-04 E I Du Pont De Nemours And Company Optimized strains of Yarrowia lipolytica for high eicosapentaenoic acid production
US8207363B2 (en) 2009-03-19 2012-06-26 Martek Biosciences Corporation Thraustochytrids, fatty acid compositions, and methods of making and uses thereof
EP3926050A1 (en) * 2009-03-19 2021-12-22 DSM IP Assets B.V. Thraustochytrids, fatty acid compositions, and methods of making and uses thereof
CN103068965A (zh) * 2009-12-28 2013-04-24 Dsmip资产公司 在蔗糖上生长的重组破囊壶菌和其组合物、制备方法及用途
CA2993690C (en) * 2010-01-19 2022-03-22 Dsm Ip Assets B.V. Eicosapentaenoic acid-producing microorganisms, fatty acid compositions, and methods of making and uses thereof
CN103282474A (zh) * 2010-04-22 2013-09-04 纳幕尔杜邦公司 从微生物生物质中获得包含多不饱和脂肪酸的组合物的方法
JP5678180B2 (ja) * 2010-06-09 2015-02-25 フォトンズ コーポレーション リミテッド 高度精製に適した、エイコサペンタエン酸を含む組成物
ES2857173T3 (es) * 2011-07-21 2021-09-28 Dsm Ip Assets Bv Aceites microbianos enriquecidos en ácidos grasos poliinsaturados

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3118954B2 (ja) 1992-05-14 2000-12-18 石川島播磨重工業株式会社 偏平ブロー成形装置
JP3196316B2 (ja) 1992-05-20 2001-08-06 石川島播磨重工業株式会社 ブロー成形装置
JP3196323B2 (ja) 1992-06-09 2001-08-06 石川島播磨重工業株式会社 偏平ブロー成形機のパリソン皺矯正装置
JP3196326B2 (ja) 1992-06-22 2001-08-06 石川島播磨重工業株式会社 偏平ブロー成形装置
JP3125443B2 (ja) 1992-07-02 2001-01-15 石川島播磨重工業株式会社 偏平ブロー成形装置

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WO2013013208A2 (en) 2013-01-24
IL230500B (en) 2018-04-30
EP3831952A1 (en) 2021-06-09
EA034980B1 (ru) 2020-04-14
AU2012285803B2 (en) 2016-08-25
MX351174B (es) 2017-10-04
NZ620578A (en) 2015-09-25
US20150223492A1 (en) 2015-08-13
PH12014500169A1 (en) 2014-02-24
CA2842374C (en) 2019-03-05
BR112014001443A2 (pt) 2017-11-21
MX2014000759A (es) 2014-05-07
CN105255738B (zh) 2024-12-27
NZ712497A (en) 2016-09-30
CN104011217A (zh) 2014-08-27
BR122015020130A2 (pt) 2019-08-27
CL2014000156A1 (es) 2014-06-13
CN119899748A (zh) 2025-04-29
CN105255738A (zh) 2016-01-20
ZA201400620B (en) 2015-12-23
EP3050972A2 (en) 2016-08-03
NZ710646A (en) 2015-12-24
CN104011217B (zh) 2018-09-04
CA2842374A1 (en) 2013-01-24
EP3050972A3 (en) 2016-11-02
IL230500A0 (en) 2014-03-31
KR102158437B1 (ko) 2020-09-22
EP4585049A2 (en) 2025-07-16
ZA201502764B (en) 2017-01-25
EP3050972B1 (en) 2020-11-18
JP2014520573A (ja) 2014-08-25
DK3050972T3 (da) 2021-02-08
JP2020036602A (ja) 2020-03-12
BR112014001443B1 (pt) 2021-11-16
US20220322705A1 (en) 2022-10-13
SG10201605966TA (en) 2016-09-29
EP2734630B1 (en) 2019-12-25
JP2017200480A (ja) 2017-11-09
AU2016256769A1 (en) 2016-12-01
KR102038715B1 (ko) 2019-10-31
ES2859752T3 (es) 2021-10-04
US20170245523A1 (en) 2017-08-31
AR087944A1 (es) 2014-04-30
ES2774778T3 (es) 2020-07-22
KR20140046469A (ko) 2014-04-18
HK1198545A1 (en) 2015-05-15
WO2013013208A3 (en) 2013-03-28
CL2015001217A1 (es) 2015-06-26
US9045785B2 (en) 2015-06-02
AU2016256769B2 (en) 2018-01-18
AU2012285803A1 (en) 2014-02-20
JP7134938B2 (ja) 2022-09-12
EA201400151A1 (ru) 2014-10-30
KR20190082331A (ko) 2019-07-09
US20150094382A1 (en) 2015-04-02
PH12014500169B1 (en) 2018-11-23
US20130172590A1 (en) 2013-07-04
EP2734630A2 (en) 2014-05-28
MY169454A (en) 2019-04-11
MX385408B (es) 2025-03-18
EP2734630A4 (en) 2015-07-29

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