KR102158437B1 - 에이코사펜타엔산-생산 미생물, 지방산 조성물, 및 이의 생산 방법 및 용도 - Google Patents

에이코사펜타엔산-생산 미생물, 지방산 조성물, 및 이의 생산 방법 및 용도 Download PDF

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KR102158437B1
KR102158437B1 KR1020197019037A KR20197019037A KR102158437B1 KR 102158437 B1 KR102158437 B1 KR 102158437B1 KR 1020197019037 A KR1020197019037 A KR 1020197019037A KR 20197019037 A KR20197019037 A KR 20197019037A KR 102158437 B1 KR102158437 B1 KR 102158437B1
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biomass
weight
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epa
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조제 알 가르시아
3세 조셉 더블유 파이퍼
존 밀톤 한센
시아오 다니엘 동
폴 와렌 베렌스
커크 이 앱트
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디에스엠 아이피 어셋츠 비.브이.
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6409—Fatty acids
    • C12P7/6427—Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K10/00—Animal feeding-stuffs
    • A23K10/10—Animal feeding-stuffs obtained by microbiological or biochemical processes
    • A23K10/16—Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/158—Fatty acids; Fats; Products containing oils or fats
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K50/00—Feeding-stuffs specially adapted for particular animals
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K50/00—Feeding-stuffs specially adapted for particular animals
    • A23K50/80—Feeding-stuffs specially adapted for particular animals for aquatic animals, e.g. fish, crustaceans or molluscs
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11B—PRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
    • C11B1/00—Production of fats or fatty oils from raw materials
    • C11B1/10—Production of fats or fatty oils from raw materials by extracting
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/12—Unicellular algae; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/12—Unicellular algae; Culture media therefor
    • C12N1/125—Unicellular algae isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6409—Fatty acids
    • C12P7/6427—Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone
    • C12P7/6432—Eicosapentaenoic acids [EPA]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/89—Algae ; Processes using algae

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Food Science & Technology (AREA)
  • Animal Husbandry (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Cell Biology (AREA)
  • Birds (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicinal Chemistry (AREA)
  • Botany (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Physiology (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Insects & Arthropods (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
KR1020197019037A 2011-07-21 2012-07-20 에이코사펜타엔산-생산 미생물, 지방산 조성물, 및 이의 생산 방법 및 용도 Active KR102158437B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161510464P 2011-07-21 2011-07-21
US61/510,464 2011-07-21
PCT/US2012/047728 WO2013013208A2 (en) 2011-07-21 2012-07-20 Eicosapentaenoic acid-producing microorganisms, fatty acid compositions, and methods of making and uses thereof

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KR1020147004428A Division KR102038715B1 (ko) 2011-07-21 2012-07-20 에이코사펜타엔산-생산 미생물, 지방산 조성물, 및 이의 생산 방법 및 용도

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KR20190082331A KR20190082331A (ko) 2019-07-09
KR102158437B1 true KR102158437B1 (ko) 2020-09-22

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KR1020197019037A Active KR102158437B1 (ko) 2011-07-21 2012-07-20 에이코사펜타엔산-생산 미생물, 지방산 조성물, 및 이의 생산 방법 및 용도

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EP (4) EP4585049A2 (enExample)
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KR (2) KR102038715B1 (enExample)
CN (3) CN104011217B (enExample)
AR (1) AR087944A1 (enExample)
AU (2) AU2012285803B2 (enExample)
BR (2) BR122015020130A2 (enExample)
CA (1) CA2842374C (enExample)
CL (2) CL2014000156A1 (enExample)
DK (1) DK3050972T3 (enExample)
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ES (2) ES2774778T3 (enExample)
IL (1) IL230500B (enExample)
MX (2) MX385408B (enExample)
MY (1) MY169454A (enExample)
PH (1) PH12014500169B1 (enExample)
SG (1) SG10201605966TA (enExample)
WO (1) WO2013013208A2 (enExample)
ZA (2) ZA201400620B (enExample)

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EP2734630B1 (en) 2019-12-25
US20170245523A1 (en) 2017-08-31
ZA201502764B (en) 2017-01-25
WO2013013208A2 (en) 2013-01-24
CA2842374A1 (en) 2013-01-24
AU2016256769B2 (en) 2018-01-18
CN104011217A (zh) 2014-08-27
IL230500A0 (en) 2014-03-31
EA034980B1 (ru) 2020-04-14
AU2012285803A1 (en) 2014-02-20
CN119899748A (zh) 2025-04-29
US20130172590A1 (en) 2013-07-04
JP2017200480A (ja) 2017-11-09
US9045785B2 (en) 2015-06-02
JP7134938B2 (ja) 2022-09-12
BR112014001443B1 (pt) 2021-11-16
CA2842374C (en) 2019-03-05
DK3050972T3 (da) 2021-02-08
BR122015020130A2 (pt) 2019-08-27
EP4585049A2 (en) 2025-07-16
AR087944A1 (es) 2014-04-30
JP2014520573A (ja) 2014-08-25
PH12014500169B1 (en) 2018-11-23
ZA201400620B (en) 2015-12-23
AU2012285803B2 (en) 2016-08-25
AU2016256769A1 (en) 2016-12-01
EA201400151A1 (ru) 2014-10-30
KR20190082331A (ko) 2019-07-09
IL230500B (en) 2018-04-30
EP3050972A3 (en) 2016-11-02
CN105255738B (zh) 2024-12-27
JP6338285B2 (ja) 2018-06-06
CL2015001217A1 (es) 2015-06-26
ES2859752T3 (es) 2021-10-04
HK1198545A1 (en) 2015-05-15
NZ620578A (en) 2015-09-25
MX385408B (es) 2025-03-18
MY169454A (en) 2019-04-11
WO2013013208A3 (en) 2013-03-28
KR20140046469A (ko) 2014-04-18
CN104011217B (zh) 2018-09-04
EP2734630A4 (en) 2015-07-29
EP3831952A1 (en) 2021-06-09
PH12014500169A1 (en) 2014-02-24
US20150223492A1 (en) 2015-08-13
CL2014000156A1 (es) 2014-06-13
ES2774778T3 (es) 2020-07-22
MX351174B (es) 2017-10-04
EP2734630A2 (en) 2014-05-28
MX2014000759A (es) 2014-05-07
EP3050972A2 (en) 2016-08-03
BR112014001443A2 (pt) 2017-11-21
US20220322705A1 (en) 2022-10-13
JP2020036602A (ja) 2020-03-12
NZ712497A (en) 2016-09-30
KR102038715B1 (ko) 2019-10-31
CN105255738A (zh) 2016-01-20
NZ710646A (en) 2015-12-24
SG10201605966TA (en) 2016-09-29
US20150094382A1 (en) 2015-04-02
EP3050972B1 (en) 2020-11-18

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