|
US2519863A
(en)
|
1949-05-14 |
1950-08-22 |
Eastman Kodak Co |
Conversion of beta-, gamma-, and delta-tocopherol to alpha-tocopherol by aminoalkylation and reduction
|
|
EP0159018A3
(en)
*
|
1984-04-17 |
1986-10-01 |
HENKEL CORPORATION (a Delaware corp.) |
Production of d-alpha-tocopherol from natural plant sources
|
|
US4977282A
(en)
|
1984-04-17 |
1990-12-11 |
Henkel Corporation |
Production of d-alpha-tocopherol from natural plant sources
|
|
US4603142A
(en)
|
1984-06-01 |
1986-07-29 |
Wisconsin Alumni Research Foundation |
Cholesterol lowering method of use
|
|
JPS636186A
(ja)
|
1986-06-23 |
1988-01-12 |
タツタ電線株式会社 |
点滴監視装置
|
|
JPH0788376B2
(ja)
|
1986-09-02 |
1995-09-27 |
エーザイ株式会社 |
光学活性α−トコトリエノ−ルの製造方法
|
|
JP2685785B2
(ja)
|
1988-03-11 |
1997-12-03 |
エーザイ株式会社 |
光学活性α−トコトリエノールの製造方法
|
|
EP0333472B1
(en)
|
1988-03-16 |
1997-10-08 |
PALM OIL RESEARCH & DEVELOPMENT BOARD |
Production of high concentration tocopherols and tocotrienols from palm oil by-products
|
|
US5157132A
(en)
*
|
1990-05-18 |
1992-10-20 |
Carotech Associates |
Integrated process for recovery of carotenoids and tocotrienols from oil
|
|
US5591772A
(en)
|
1991-11-22 |
1997-01-07 |
Lipogenics, Inc. |
Tocotrienols and tocotrienol-like compounds and methods for their use
|
|
DE59605564D1
(de)
*
|
1995-03-28 |
2000-08-17 |
Hoffmann La Roche |
Aminomethylierung von Tocopherolen
|
|
US5660691A
(en)
|
1995-11-13 |
1997-08-26 |
Eastman Chemical Company |
Process for the production of tocotrienol/tocopherol blend concentrates
|
|
US6232060B1
(en)
|
1996-01-19 |
2001-05-15 |
Galileo Laboratories, Inc. |
Assay system for anti-stress agents
|
|
US5801159A
(en)
|
1996-02-23 |
1998-09-01 |
Galileo Laboratories, Inc. |
Method and composition for inhibiting cellular irreversible changes due to stress
|
|
US5932748A
(en)
|
1997-06-06 |
1999-08-03 |
Roche Vitamins Inc. |
Process for permethylating non-α-tocopherols to produce α-tocopherol
|
|
JP4267815B2
(ja)
*
|
1997-10-29 |
2009-05-27 |
フレクシス アメリカ エル． ピー． |
過酸化水素及び触媒を使用してフェニレンジアミンからキノンジイミンを製造する方法
|
|
CN1295568A
(zh)
|
1998-01-29 |
2001-05-16 |
伊斯曼化学公司 |
从含有母育酚的混合物中分离生育三烯酚的方法及其组合物
|
|
JP3258003B2
(ja)
*
|
1998-11-06 |
2002-02-18 |
富士化学工業株式会社 |
トコトリエノール類含有粉末、その製造方法およびそれを圧縮成型してなる錠剤
|
|
US6395915B1
(en)
|
1999-09-10 |
2002-05-28 |
Technikrom, Inc. |
Method for producing purified tocotrienols and tocopherols using liquid chromatography
|
|
MY127451A
(en)
|
1999-11-04 |
2006-12-29 |
Malaysian Palm Oil Board |
A method of chromatographic isolation for vitamin e isomers
|
|
DE10034233A1
(de)
*
|
2000-07-14 |
2002-01-24 |
Basf Ag |
Tocotrienolchinon-Cyclisierungsprodukte
|
|
US7034054B2
(en)
|
2000-12-15 |
2006-04-25 |
Galileo Pharmaceuticals, Inc. |
Methods for the prevention and treatment of cerebral ischemia using non-alpha tocopherols
|
|
US6838104B2
(en)
|
2000-12-20 |
2005-01-04 |
Archer Daniels Midland Company |
Process for the production of tocotrienols
|
|
US6608196B2
(en)
|
2001-05-03 |
2003-08-19 |
Galileo Pharmaceuticals, Inc. |
Process for solid supported synthesis of pyruvate-derived compounds
|
|
JP4842455B2
(ja)
|
2001-06-13 |
2011-12-21 |
コマツＮｔｃ株式会社 |
半導体単結晶引上げ装置及びそのライン構成
|
|
JP2003171376A
(ja)
|
2001-09-27 |
2003-06-20 |
Lion Corp |
トコフェロール類及びトコトリエノール類濃縮物、その製造方法
|
|
US6667330B2
(en)
|
2002-01-31 |
2003-12-23 |
Galileo Pharmaceuticals, Inc. |
Furanone derivatives
|
|
US6653346B1
(en)
|
2002-02-07 |
2003-11-25 |
Galileo Pharmaceuticals, Inc. |
Cytoprotective benzofuran derivatives
|
|
US6590113B1
(en)
|
2002-03-26 |
2003-07-08 |
Ronald T. Sleeter |
Process for treating oils containing antioxidant compounds
|
|
US7491312B2
(en)
|
2002-10-30 |
2009-02-17 |
Edison Pharmaceuticals, Inc. |
Identifying therapeutic compounds based on their physical-chemical properties
|
|
MY130618A
(en)
|
2002-11-27 |
2007-07-31 |
Malaysian Palm Oil Board |
A method of extracting and isolating minor components from vegetable oil
|
|
CA2580584C
(en)
|
2003-09-19 |
2015-07-28 |
Galileo Pharmaceuticals, Inc. |
Use of alpha-tocotrienol for treatment of mitochondrial diseases
|
|
WO2005035490A2
(en)
|
2003-10-10 |
2005-04-21 |
Yasoo Health, Inc. |
PROCESS FOR SYNTHESIZING d-TOCOTRIENOLS
|
|
MY173044A
(en)
|
2003-11-19 |
2019-12-20 |
Carotech Bhd |
Recovery of phytonutriens from oils
|
|
US7393662B2
(en)
|
2004-09-03 |
2008-07-01 |
Centocor, Inc. |
Human EPO mimetic hinge core mimetibodies, compositions, methods and uses
|
|
EP2471530B1
(en)
|
2005-06-01 |
2017-01-11 |
Edison Pharmaceuticals, Inc. |
Redox-active therapeutics for treatment of mitochondrial diseases and other conditions and modulation of energy biomarkers
|
|
US7432305B2
(en)
|
2005-09-15 |
2008-10-07 |
Edison Pharmaceuticals, Inc. |
Tail variants of redox-active therapeutics for treatment of mitochondrial diseases and other conditions and modulation of energy biomarkers
|
|
CA2635280C
(en)
|
2006-02-22 |
2017-12-12 |
Edison Pharmaceuticals, Inc. |
Side chain variants of redox-active therapeutics for treatment of mitochondrial diseases and other conditions and modulation of energy biomarkers
|
|
WO2007105297A1
(ja)
*
|
2006-03-13 |
2007-09-20 |
Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo |
メチン系色素とその用途
|
|
AU2008205263A1
(en)
|
2007-01-10 |
2008-07-17 |
Edison Pharmaceuticals, Inc. |
Treatment of respiratory chain disorders using compounds having erythropoietin or thrombopoietin activity
|
|
WO2008142433A1
(en)
|
2007-05-24 |
2008-11-27 |
Loders Croklaan B.V. |
Process for producing compositions comprising tocoherols and tocotrienols
|
|
EA028911B1
(ru)
|
2007-11-06 |
2018-01-31 |
Биоэлектрон Текнолоджи Корпорейшн |
ПРОИЗВОДНЫЕ 4-(п-ХИНОНИЛ)-2-ГИДРОКСИБУТАНАМИДА ДЛЯ ЛЕЧЕНИЯ МИТОХОНДРИАЛЬНЫХ ЗАБОЛЕВАНИЙ
|
|
JP2011508777A
(ja)
|
2008-01-07 |
2011-03-17 |
セントコア・オーソ・バイオテツク・インコーポレーテツド |
エリスロポエチン低応答性貧血を治療する方法
|
|
WO2009089224A1
(en)
|
2008-01-08 |
2009-07-16 |
Edison Pharmaceuticals, Inc. |
(HET) ARYL-p-QUINONE DERIVATIVES FOR TREATMENT OF MITOCHONDRIAL DISEASES
|
|
WO2009111543A2
(en)
*
|
2008-03-05 |
2009-09-11 |
Edison Pharmaceuticals, Inc. |
Treatment of hearing and balance impairments with redox-active therapeutics
|
|
EP2262508B1
(en)
|
2008-03-05 |
2018-10-03 |
BioElectron Technology Corporation |
SUBSTITUTED-p-QUINONE DERIVATIVES FOR TREATMENT OF OXIDATIVE STRESS DISEASES
|
|
US20110142834A1
(en)
|
2008-05-15 |
2011-06-16 |
Edison Pharmaceuticals, Inc. |
Treatment of hearing and balance impairments using compounds having erythropoietin activity
|
|
US20090291092A1
(en)
|
2008-05-22 |
2009-11-26 |
Miller Guy M |
Treatment of mitochondrial diseases with an erythropoietin mimetic
|
|
US8716486B2
(en)
|
2008-06-25 |
2014-05-06 |
Edison Pharmaceuticals, Inc. |
2-heterocyclylaminoalkyl-(p-quinone) derivatives for treatment of oxidative stress diseases
|
|
WO2010005989A1
(en)
|
2008-07-09 |
2010-01-14 |
Edison Pharmaceuticals, Inc. |
Dermatological compositions with anti-aging and skin even-toning properties
|
|
US20100029784A1
(en)
|
2008-07-30 |
2010-02-04 |
Hinman Andrew W |
Naphthoquinone compositions with anti-aging, anti-inflammatory and skin even-toning properties
|
|
WO2010014758A1
(en)
|
2008-07-30 |
2010-02-04 |
Edison Pharmaceuticals, Inc. |
Use of hydrogenated pyrido[4,3-b] indoles for the treatment of oxidative stress
|
|
LT3827815T
(lt)
|
2008-09-10 |
2023-10-10 |
Ptc Therapeutics, Inc. |
Psichologinių raidos sutrikimų gydymas oksidacijos redukcijos atžvilgiu aktyviais vaistais
|
|
EP2362726B1
(en)
|
2008-10-14 |
2018-08-08 |
Bioelectron Technology Corporation |
Treatment of oxidative stress disorders including contrast nephropathy, radiation damage and disruptions in the function of red cells
|
|
PT2362875E
(pt)
*
|
2008-10-28 |
2015-11-03 |
Edison Pharmaceuticals Inc |
Processo para a produção de alfa-tocotrienol e seus derivados
|
|
MX336800B
(es)
|
2009-04-28 |
2016-02-02 |
Edison Pharmaceuticals Inc |
Tratamiento de neuropatia optica hereditaria de leber y atrofia optica dominante con tocotrienol quinonas.
|
|
BRPI1015006A2
(pt)
|
2009-04-28 |
2019-09-24 |
Ampere Life Sciences Inc |
uso tópico, periocular, ou intraocular de tocotrienóis para o tratamento de doenças oftálmicas
|
|
MX2011011310A
(es)
|
2009-04-28 |
2011-11-18 |
Edison Pharmaceuticals Inc |
Formulacion de tocotrienol quinonas para el tratamiento de enfermedades oftalmicas.
|
|
JP2012531411A
(ja)
|
2009-06-25 |
2012-12-10 |
アンペア ライフ サイエンシーズ，インコーポレイテッド |
トコトリエノールまたはトコトリエノール濃縮抽出物を用いた広汎性発達障害の処置
|
|
CN102647981B
(zh)
|
2009-08-26 |
2016-09-28 |
爱迪生制药有限公司 |
预防和治疗脑缺血的方法
|
|
WO2011082355A1
(en)
|
2009-12-31 |
2011-07-07 |
Edison Pharmaceuticals, Inc. |
Treatment of leigh syndrome and leigh-like syndrome with tocotrienol quinones
|
|
AU2011224411A1
(en)
|
2010-03-09 |
2012-10-18 |
Penwest Pharmaceuticals Co. |
Synthesis of alpha-tocopherolquinone derivatives, and methods of using the same
|
|
WO2011113018A1
(en)
|
2010-03-12 |
2011-09-15 |
Ampere Life Sciences, Inc. |
Measurement and control of biological time
|
|
US20130116336A1
(en)
|
2010-04-06 |
2013-05-09 |
William D. Shrader |
Treatment of ataxia telangiectasia
|
|
SG185046A1
(en)
|
2010-04-27 |
2012-12-28 |
Edison Pharmaceuticals Inc |
Formulations of quinones for the treatment of ophthalmic diseases
|
|
WO2012009271A1
(en)
|
2010-07-14 |
2012-01-19 |
Penwest Pharmaceuticals Co. |
Methods of providing anticoagulation effects in subjects
|
|
CA2807507A1
(en)
|
2010-08-06 |
2012-02-09 |
Edison Pharmaceuticals, Inc. |
Treatment of mitochondrial diseases with naphthoquinones
|
|
WO2012068552A1
(en)
|
2010-11-19 |
2012-05-24 |
Edison Pharmaceuticals, Inc. |
Methods for improving blood glucose control
|
|
WO2012154613A1
(en)
|
2011-05-06 |
2012-11-15 |
Edison Pharmaceuticals, Inc. |
Improved process for the preparation of d-alpha-tocotrienol from natural extracts
|
|
WO2012170773A1
(en)
|
2011-06-08 |
2012-12-13 |
Edison Pharmaceuticals, Inc. |
Adjunctive therapy for the treatment of mitochondrial disorders with quinones and naphthoquinones
|
|
WO2012174286A1
(en)
|
2011-06-14 |
2012-12-20 |
Edison Pharmaceuticals, Inc. |
Catechol derivatives for treatment of oxidative stress diseases
|
|
WO2013006736A1
(en)
|
2011-07-06 |
2013-01-10 |
Edison Pharmaceuticals, Inc |
Treatment of leigh syndrome and leigh-like syndrome, including complications of sucla2 mutations, with tocotrienol quinones
|
|
ES2795798T3
(es)
|
2011-07-06 |
2020-11-24 |
Ptc Therapeutics Inc |
Tratamiento de aciduria metilmalónica, aciduria isovalérica, y otras acidurias orgánicas con tocotrienol quinonas
|
|
CA2842486C
(en)
|
2011-07-19 |
2022-09-06 |
Edison Pharmaceuticals, Inc. |
Methods for oxidation of alpha tocotrienol in the presence of non-alpha tocotrienols
|
|
WO2014039917A1
(en)
|
2012-09-07 |
2014-03-13 |
Edison Pharmaceuticals, Inc. |
Benzoquinone derivatives for treating oxidative stress disorders
|
|
US8937191B2
(en)
|
2012-12-20 |
2015-01-20 |
Orochem Technologies, Inc. |
Recovery of highly pure alpha-tocotrienol from crude palm oil extract
|
|
CA2902506C
(en)
|
2013-03-08 |
2024-11-19 |
Unilever Global Ip Limited |
Resorcinol compounds for dermatological use
|
|
US20140275045A1
(en)
|
2013-03-15 |
2014-09-18 |
Edison Pharmaceuticals, Inc. |
Phenazine-3-one and phenothiazine-3-one derivatives for treatment of oxidative stress disorders
|
|
US9868711B2
(en)
|
2013-03-15 |
2018-01-16 |
Bioelectron Technology Corporation |
Phenazine-3-one and phenothiazine-3-one derivatives for treatment of oxidative stress disorders
|
|
US9296712B2
(en)
|
2013-03-15 |
2016-03-29 |
Edison Pharmaceuticals, Inc. |
Resorufin derivatives for treatment of oxidative stress disorders
|
|
HK1220451A1
(zh)
|
2013-03-15 |
2017-05-05 |
Bioelectron Technology Corporation |
用於治疗氧化应激障碍的烷基-杂芳基取代醌衍生物
|
|
US9670170B2
(en)
|
2013-03-15 |
2017-06-06 |
Bioelectron Technology Corporation |
Resorufin derivatives for treatment of oxidative stress disorders
|
|
JP2016520621A
(ja)
|
2013-05-31 |
2016-07-14 |
エジソン ファーマシューティカルズ， インコーポレイテッド |
酸化ストレス障害の処置のためのカルボン酸誘導体
|
|
WO2016100579A1
(en)
|
2014-12-16 |
2016-06-23 |
Edison Pharmaceuticals, Inc., |
Polymorphic and amorphous forms of (r)-2-hydroxy-2-methyl-4-(2,4,5-trimethyl-3,6-dioxocyclohexa-1,4-dienyl)butanamide
|
|
WO2016100576A1
(en)
|
2014-12-16 |
2016-06-23 |
Edison Pharmaceuticals, Inc. |
Methods for chiral resolution of trolox
|
|
JP2018502127A
(ja)
|
2015-01-12 |
2018-01-25 |
バイオエレクトロン テクノロジー コーポレイション |
放射線被曝に対する防護のためのキノン
|
|
JP7117241B2
(ja)
|
2015-12-16 |
2022-08-12 |
ピーティーシー セラピューティクス， インコーポレイテッド |
混合されたトコール組成物からアルファ－トコトリエノールを富化するための改良された方法
|
|
CA3008849A1
(en)
|
2015-12-17 |
2017-06-22 |
Bioelectron Technology Corporation |
Flouroalkyl, flouroalkoxy, phenoxy, heteroaryloxy, alkoxy, and amine 1,4-benzoquinone derivatives for treatment of oxidative stress disorders
|
|
WO2017123823A1
(en)
|
2016-01-12 |
2017-07-20 |
Bioelectron Technology Corporation |
Alkyl-, acyl-, urea-, and aza-uracil sulfide:quinone oxidoreductase inhibitors
|
|
WO2017123820A1
(en)
|
2016-01-12 |
2017-07-20 |
Bioelectron Technology Corporation |
Methods for diagnosing and treating oxidative stress disorders using biomarkers
|
|
WO2018081644A1
(en)
|
2016-10-28 |
2018-05-03 |
Bioelectron Technology Corporation |
Methods of analyzing p-hydroquinone levels and ratios
|
|
WO2018093957A1
(en)
|
2016-11-15 |
2018-05-24 |
Bioelectron Technology Corporation |
2-substituted amino-naphth[1,2-d]imidazol-5-one compounds or pharmaceutically acceptable salts thereof cross reference to related applications
|
|
WO2018129411A1
(en)
|
2017-01-06 |
2018-07-12 |
Bioelectron Technology Corporation |
Aryl- and heteroaryl-resorufin derivatives for treatment of oxidative stress disorders and liver and kidney disorders
|
|
CA3097114A1
(en)
|
2017-04-14 |
2018-10-18 |
Bioelectron Technology Corporation |
Methods and compositions for treatment of inflammation and oxidative stress
|