JP2014193892A5 - - Google Patents
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- JP2014193892A5 JP2014193892A5 JP2014101360A JP2014101360A JP2014193892A5 JP 2014193892 A5 JP2014193892 A5 JP 2014193892A5 JP 2014101360 A JP2014101360 A JP 2014101360A JP 2014101360 A JP2014101360 A JP 2014101360A JP 2014193892 A5 JP2014193892 A5 JP 2014193892A5
- Authority
- JP
- Japan
- Prior art keywords
- affinity chromatography
- ligand
- amino acid
- domains
- spa
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 238000001042 affinity chromatography Methods 0.000 claims 16
- 239000003446 ligand Substances 0.000 claims 14
- 235000001014 amino acid Nutrition 0.000 claims 10
- 150000001413 amino acids Chemical class 0.000 claims 10
- 239000012504 chromatography matrix Substances 0.000 claims 6
- 230000035772 mutation Effects 0.000 claims 6
- 230000037430 deletion Effects 0.000 claims 4
- 238000012217 deletion Methods 0.000 claims 4
- 241000191940 Staphylococcus Species 0.000 claims 3
- 235000018102 proteins Nutrition 0.000 claims 3
- 102000004169 proteins and genes Human genes 0.000 claims 3
- 108090000623 proteins and genes Proteins 0.000 claims 3
- 239000004471 Glycine Substances 0.000 claims 1
- DHMQDGOQFOQNFH-UHFFFAOYSA-N Glycine Natural products NCC(O)=O DHMQDGOQFOQNFH-UHFFFAOYSA-N 0.000 claims 1
- 239000004472 Lysine Substances 0.000 claims 1
- KDXKERNSBIXSRK-UHFFFAOYSA-N Lysine Natural products NCCCCC(N)C(O)=O KDXKERNSBIXSRK-UHFFFAOYSA-N 0.000 claims 1
- 235000004279 alanine Nutrition 0.000 claims 1
- 238000013467 fragmentation Methods 0.000 claims 1
- 238000006062 fragmentation reaction Methods 0.000 claims 1
- 239000007787 solid Substances 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161494701P | 2011-06-08 | 2011-06-08 | |
| US61/494,701 | 2011-06-08 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012124067A Division JP5756428B2 (ja) | 2011-06-08 | 2012-05-31 | 新規なスタフィロコッカス・アウレウス（Ｓｔａｐｈｙｌｏｃｏｃｃｕｓａｕｒｅｕｓ）プロテインＡベースのリガンドを含むクロマトグラフィーマトリックス |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016140214A Division JP6189493B2 (ja) | 2011-06-08 | 2016-07-15 | 新規なスタフィロコッカス・アウレウス（Ｓｔａｐｈｙｌｏｃｏｃｃｕｓ ａｕｒｅｕｓ）プロテインＡベースのリガンドを含むクロマトグラフィーマトリックス |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014193892A JP2014193892A (ja) | 2014-10-09 |
| JP2014193892A5 true JP2014193892A5 (enExample) | 2015-07-16 |
| JP6018120B2 JP6018120B2 (ja) | 2016-11-02 |
Family
ID=46229293
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012124067A Active JP5756428B2 (ja) | 2011-06-08 | 2012-05-31 | 新規なスタフィロコッカス・アウレウス（Ｓｔａｐｈｙｌｏｃｏｃｃｕｓａｕｒｅｕｓ）プロテインＡベースのリガンドを含むクロマトグラフィーマトリックス |
| JP2014101360A Active JP6018120B2 (ja) | 2011-06-08 | 2014-05-15 | 新規なスタフィロコッカス・アウレウス（Ｓｔａｐｈｙｌｏｃｏｃｃｕｓａｕｒｅｕｓ）プロテインＡベースのリガンドを含むクロマトグラフィーマトリックス |
| JP2016140214A Active JP6189493B2 (ja) | 2011-06-08 | 2016-07-15 | 新規なスタフィロコッカス・アウレウス（Ｓｔａｐｈｙｌｏｃｏｃｃｕｓ ａｕｒｅｕｓ）プロテインＡベースのリガンドを含むクロマトグラフィーマトリックス |
| JP2017148843A Active JP6586131B2 (ja) | 2011-06-08 | 2017-08-01 | 新規なスタフィロコッカス・アウレウス（Ｓｔａｐｈｙｌｏｃｏｃｃｕｓ ａｕｒｅｕｓ）プロテインＡベースのリガンドを含むクロマトグラフィーマトリックス |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012124067A Active JP5756428B2 (ja) | 2011-06-08 | 2012-05-31 | 新規なスタフィロコッカス・アウレウス（Ｓｔａｐｈｙｌｏｃｏｃｃｕｓａｕｒｅｕｓ）プロテインＡベースのリガンドを含むクロマトグラフィーマトリックス |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016140214A Active JP6189493B2 (ja) | 2011-06-08 | 2016-07-15 | 新規なスタフィロコッカス・アウレウス（Ｓｔａｐｈｙｌｏｃｏｃｃｕｓ ａｕｒｅｕｓ）プロテインＡベースのリガンドを含むクロマトグラフィーマトリックス |
| JP2017148843A Active JP6586131B2 (ja) | 2011-06-08 | 2017-08-01 | 新規なスタフィロコッカス・アウレウス（Ｓｔａｐｈｙｌｏｃｏｃｃｕｓ ａｕｒｅｕｓ）プロテインＡベースのリガンドを含むクロマトグラフィーマトリックス |
Country Status (13)
| Country | Link |
|---|---|
| US (5) | US8754196B2 (enExample) |
| EP (2) | EP3053931B1 (enExample) |
| JP (4) | JP5756428B2 (enExample) |
| KR (3) | KR101464040B1 (enExample) |
| CN (2) | CN102895960B (enExample) |
| AU (3) | AU2012366229C1 (enExample) |
| DK (2) | DK3053931T3 (enExample) |
| ES (2) | ES2671722T3 (enExample) |
| IL (2) | IL229774A (enExample) |
| RU (2) | RU2644680C1 (enExample) |
| SG (3) | SG186552A1 (enExample) |
| TW (3) | TWI638828B (enExample) |
| WO (1) | WO2013109302A2 (enExample) |
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| US8877688B2 (en) | 2007-09-14 | 2014-11-04 | Adimab, Llc | Rationally designed, synthetic antibody libraries and uses therefor |
| US12529164B2 (en) | 2007-09-14 | 2026-01-20 | Adimab, Llc | Rationally designed, synthetic antibody libraries and uses therefor |
| US8592555B2 (en) | 2008-08-11 | 2013-11-26 | Emd Millipore Corporation | Immunoglobulin-binding proteins with improved specificity |
| SG195555A1 (en) | 2008-12-24 | 2013-12-30 | Emd Millipore Corp | Caustic stable chromatography ligands |
| SG186552A1 (en) | 2011-06-08 | 2013-01-30 | Emd Millipore Corp | Chromatography matrices including novel staphylococcus aureus protein a based ligands |
| WO2013081540A1 (en) * | 2011-11-30 | 2013-06-06 | Ge Healthcare Bio-Sciences Ab | Affinity chromatography matrix |
| EP2682168A1 (en) | 2012-07-02 | 2014-01-08 | Millipore Corporation | Purification of biological molecules |
| SG11201406407TA (en) | 2012-06-29 | 2014-11-27 | Emd Millipore Corp | Methods for inactivating viruses during a protein purification process |
| IN2015DN02055A (enExample) | 2012-09-17 | 2015-08-14 | Grace W R & Co | |
| KR102226564B1 (ko) | 2012-09-17 | 2021-03-10 | 더블유.알. 그레이스 앤드 캄파니-콘. | 작용화된 미립자 지지체 물질 및 이의 제조 및 사용 방법 |
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| JP6805831B2 (ja) | 2015-02-05 | 2020-12-23 | 三菱ケミカル株式会社 | 免疫グロブリンに親和性を有するタンパク質、およびそれを用いたアフィニティ分離剤、液体クロマトグラフィー用カラム |
| JP6738340B2 (ja) | 2015-02-06 | 2020-08-12 | ナフィゴ プロテインズ ゲゼルシャフト ミット ベシュレンクテル ハフツングＮａｖｉｇｏ Ｐｒｏｔｅｉｎｓ ＧｍｂＨ | 新規なｅｇｆｒ結合タンパク質 |
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| JP2018520675A (ja) | 2015-07-20 | 2018-08-02 | ナフィゴ プロテインズ ゲゼルシャフト ミット ベシュレンクテル ハフツングＮａｖｉｇｏ Ｐｒｏｔｅｉｎｓ ＧｍｂＨ | ジユビキチン変異タンパク質をベースとした新規結合タンパク質及びその生成方法 |
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| US10730908B2 (en) | 2016-05-11 | 2020-08-04 | Ge Healthcare Bioprocess R&D Ab | Separation method |
| US10889615B2 (en) | 2016-05-11 | 2021-01-12 | Cytiva Bioprocess R&D Ab | Mutated immunoglobulin-binding polypeptides |
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