JP2014224126A5 - - Google Patents

Download PDF

Info

Publication number
JP2014224126A5
JP2014224126A5 JP2014143781A JP2014143781A JP2014224126A5 JP 2014224126 A5 JP2014224126 A5 JP 2014224126A5 JP 2014143781 A JP2014143781 A JP 2014143781A JP 2014143781 A JP2014143781 A JP 2014143781A JP 2014224126 A5 JP2014224126 A5 JP 2014224126A5
Authority
JP
Japan
Prior art keywords
peptide
composition
carrier
group
cargo
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2014143781A
Other languages
English (en)
Japanese (ja)
Other versions
JP2014224126A (ja
JP5937643B2 (ja
Filing date
Publication date
Application filed filed Critical
Publication of JP2014224126A publication Critical patent/JP2014224126A/ja
Publication of JP2014224126A5 publication Critical patent/JP2014224126A5/ja
Application granted granted Critical
Publication of JP5937643B2 publication Critical patent/JP5937643B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2014143781A 2007-01-19 2014-07-14 ペプチド組成物の安定性および送達効率を上昇させるための修飾方法 Active JP5937643B2 (ja)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US88141907P 2007-01-19 2007-01-19
US60/881,419 2007-01-19
US94528507P 2007-06-20 2007-06-20
US60/945,285 2007-06-20

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2009546577A Division JP2010516707A (ja) 2007-01-19 2008-01-22 ペプチド組成物の安定性および送達効率を上昇させるための修飾方法

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2016096016A Division JP2016147905A (ja) 2007-01-19 2016-05-12 ペプチド組成物の安定性および送達効率を上昇させるための修飾方法

Publications (3)

Publication Number Publication Date
JP2014224126A JP2014224126A (ja) 2014-12-04
JP2014224126A5 true JP2014224126A5 (enExample) 2015-07-16
JP5937643B2 JP5937643B2 (ja) 2016-06-22

Family

ID=39636771

Family Applications (7)

Application Number Title Priority Date Filing Date
JP2009546577A Ceased JP2010516707A (ja) 2007-01-19 2008-01-22 ペプチド組成物の安定性および送達効率を上昇させるための修飾方法
JP2014143781A Active JP5937643B2 (ja) 2007-01-19 2014-07-14 ペプチド組成物の安定性および送達効率を上昇させるための修飾方法
JP2016096016A Pending JP2016147905A (ja) 2007-01-19 2016-05-12 ペプチド組成物の安定性および送達効率を上昇させるための修飾方法
JP2018058012A Pending JP2018111717A (ja) 2007-01-19 2018-03-26 ペプチド組成物の安定性および送達効率を上昇させるための修飾方法
JP2021036134A Pending JP2021098725A (ja) 2007-01-19 2021-03-08 ペプチド組成物の安定性および送達効率を上昇させるための修飾方法
JP2023049966A Pending JP2023078424A (ja) 2007-01-19 2023-03-27 ペプチド組成物の安定性および送達効率を上昇させるための修飾方法
JP2025170793A Pending JP2025185093A (ja) 2007-01-19 2025-10-09 ペプチド組成物の安定性および送達効率を上昇させるための修飾方法

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP2009546577A Ceased JP2010516707A (ja) 2007-01-19 2008-01-22 ペプチド組成物の安定性および送達効率を上昇させるための修飾方法

Family Applications After (5)

Application Number Title Priority Date Filing Date
JP2016096016A Pending JP2016147905A (ja) 2007-01-19 2016-05-12 ペプチド組成物の安定性および送達効率を上昇させるための修飾方法
JP2018058012A Pending JP2018111717A (ja) 2007-01-19 2018-03-26 ペプチド組成物の安定性および送達効率を上昇させるための修飾方法
JP2021036134A Pending JP2021098725A (ja) 2007-01-19 2021-03-08 ペプチド組成物の安定性および送達効率を上昇させるための修飾方法
JP2023049966A Pending JP2023078424A (ja) 2007-01-19 2023-03-27 ペプチド組成物の安定性および送達効率を上昇させるための修飾方法
JP2025170793A Pending JP2025185093A (ja) 2007-01-19 2025-10-09 ペプチド組成物の安定性および送達効率を上昇させるための修飾方法

Country Status (8)

Country Link
US (7) US8067532B2 (enExample)
EP (2) EP2109619B1 (enExample)
JP (7) JP2010516707A (enExample)
KR (4) KR20090115852A (enExample)
CN (3) CN103524623A (enExample)
AU (1) AU2008206077A1 (enExample)
CA (2) CA2989778C (enExample)
WO (1) WO2008089491A2 (enExample)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007093042A1 (en) 2006-02-13 2007-08-23 Alethia Biotherapeutics Inc. Polynucleotides and polypeptide sequences involved in the process of bone remodeling
US8168181B2 (en) 2006-02-13 2012-05-01 Alethia Biotherapeutics, Inc. Methods of impairing osteoclast differentiation using antibodies that bind siglec-15
KR101552843B1 (ko) 2006-11-16 2015-09-14 카이 파마슈티컬즈 부갑상선 기능항진증 및 고칼슘혈증 장애의 치료를 위한 폴리양이온성 칼슘 조절제 펩타이드
CN103524623A (zh) 2007-01-19 2014-01-22 凯制药公司 肽组合物的修饰以提高稳定性和递送效率
US20090318351A1 (en) * 2008-03-12 2009-12-24 Kevin Grimes Method of treating acute st-elevation myocardial infarction with a delta pkc antagonist
US20100311671A1 (en) * 2009-03-25 2010-12-09 Kai Pharmaceuticals Transdermal delivery of pkc modulatory peptides through microporated skin
PT2459208T (pt) 2009-07-29 2017-01-03 Kai Pharmaceuticals Inc Agentes terapêuticos para redução dos niveis de hormona paratiroideia
SMT201700081T1 (it) 2011-06-08 2017-03-08 Kai Pharmaceuticals Inc Agenti terapeutici per la regolazione del fosforo sierico
JP6382111B2 (ja) * 2012-03-01 2018-08-29 ノヴォ ノルディスク アー/エス N末端改変オリゴペプチド及びその使用
CA2928851A1 (en) 2012-07-19 2014-01-23 Alethia Biotherapeutics Inc. Anti-siglec-15 antibodies
HK1215681A1 (zh) 2013-04-18 2016-09-09 Armo Biosciences, Inc. 使用白细胞介素-10治疗疾病和病症的方法
US9823255B2 (en) 2013-06-17 2017-11-21 Armo Biosciences, Inc. Method for assessing protein identity and stability
LT3013318T (lt) * 2013-06-28 2017-09-11 Amgen Inc. Stabili amg 416 (velcalcetide) kompozicija
AU2014311432A1 (en) 2013-08-30 2016-03-03 Armo Biosciences, Inc. Methods of using interleukin-10 for treating diseases and disorders
CN105828878A (zh) 2013-10-28 2016-08-03 恩格姆生物制药公司 癌症模型及相关方法
CA2928710A1 (en) 2013-11-11 2015-05-14 Armo Biosciences, Inc. Methods of using interleukin-10 for treating diseases and disorders
WO2015187295A2 (en) 2014-06-02 2015-12-10 Armo Biosciences, Inc. Methods of lowering serum cholesterol
WO2016060996A2 (en) 2014-10-14 2016-04-21 Armo Biosciences, Inc. Interleukin-15 compositions and uses thereof
CA2963995A1 (en) 2014-10-22 2016-04-28 Armo Biosciences, Inc. Methods of using interleukin-10 for treating diseases and disorders
US10456475B2 (en) 2015-02-03 2019-10-29 Kennsaw State University Research and Service Foundation, Inc. Cell penetrating protein adaptor molecules and their application in research and medicine
WO2016126615A1 (en) 2015-02-03 2016-08-11 Armo Biosciences, Inc. Methods of using interleukin-10 for treating diseases and disorders
HK1246201A1 (zh) 2015-05-28 2018-09-07 Armo Biosciences, Inc. 用於治疗癌症的聚乙二醇化白细胞介素-10
HK1245671A1 (zh) 2015-05-29 2018-08-31 Armo Biosciences, Inc. 使用白细胞介素-10治疗疾病和病症的方法
US10435446B2 (en) 2015-06-03 2019-10-08 Kennesaw State University Research and Service Foundation Inc. Cell penetrating protein adaptor molecules and their application in research and medicine
ES3039640T3 (en) 2015-08-25 2025-10-23 Armo Biosciences Inc Methods of using interleukin-10 for treating diseases and disorders
MX2018006610A (es) * 2015-12-02 2019-05-27 Inst Nat De La Rech Agronomique Inra Nuevos peptidos que tienen actividad antimicrobiana y nueva enzima capaces de convertir un residuo de configuracion l en un aminoacido de configuracion d en un peptido.
WO2017136534A1 (en) 2016-02-03 2017-08-10 Kennesaw State University Researcha And Service Foundation, Inc. Signal molecules as cell penetration agents
US11246905B2 (en) 2016-08-15 2022-02-15 President And Fellows Of Harvard College Treating infections using IdsD from Proteus mirabilis
KR101772449B1 (ko) 2016-12-27 2017-08-30 주식회사 하이센스바이오 신규한 펩타이드
CA3087881A1 (en) 2017-01-17 2018-07-26 Michael David FORREST Therapeutic inhibitors of the reverse mode of atp synthase
BR112019028172A2 (pt) 2017-07-13 2020-10-06 Michael David Forrest moduladores terapêuticos do modo reverso da atp sintase
US20200353050A1 (en) 2017-11-10 2020-11-12 Armo Biosciences, Inc. Compositions and methods of use of interleukin-10 in combination with immune check-point pathway inhibitors
MX2020010071A (es) * 2018-03-29 2021-01-08 Contrafect Corp Polipeptidos anti-microbianos, derivados de bacteriofago, y sus usos contra bacterias gram negativas.
US20210347842A1 (en) 2018-06-19 2021-11-11 Eli Lilly And Company Compositions and methods of use of il-10 agents in conjunction with chimeric antigen receptor cell therapy
US10905738B2 (en) * 2018-07-05 2021-02-02 Biozeus Desenvolvimento De Produtos Biofarmacêuticos Synthetic peptides, prodrugs, pharmaceutical compositions and uses
GB201903873D0 (en) * 2019-03-21 2019-05-08 Univ Nottingham Enhanced transfection
JP7545690B2 (ja) 2019-07-02 2024-09-05 Agc株式会社 ペプチド及びその製造方法
EP4058466A1 (en) 2019-11-13 2022-09-21 Amunix Pharmaceuticals, Inc. Barcoded xten polypeptides and compositions thereof, and methods for making and using the same
KR20230135586A (ko) 2021-01-24 2023-09-25 마이클 데이비드 포레스트 Atp 합성효소 억제제 - 미용 및 치료 용도
WO2023048236A1 (ja) 2021-09-22 2023-03-30 Agc株式会社 ペプチド
KR102380732B1 (ko) 2021-09-23 2022-04-04 엘이솔루션 주식회사 축산분뇨처리시스템
EP4463135A2 (en) 2022-01-10 2024-11-20 Sana Biotechnology, Inc. Methods of ex vivo dosing and administration of lipid particles or viral vectors and related systems and uses
US20250222027A1 (en) 2022-04-01 2025-07-10 Sana Biotechnology, Inc. Cytokine receptor agonist and viral vector combination therapies

Family Cites Families (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US615977A (en) * 1898-12-13 Car-fender
US6316003B1 (en) 1989-12-21 2001-11-13 Whitehead Institute For Biomedical Research Tat-derived transport polypeptides
US5783405A (en) * 1994-02-01 1998-07-21 Terrapin Technologies, Inc. Rapid screening method for effectors of signal transduction
US5935803A (en) * 1994-02-01 1999-08-10 Terrapin Technologies, Inc. Methods to identify immunomodulators using cognate interaction of PKC-theta
US5776716A (en) * 1994-02-01 1998-07-07 Terrapin Technologies, Inc. Methods for identifying agents which block the interaction of fyn with PKC-theta, and uses thereof
US6165977A (en) 1996-10-18 2000-12-26 Board Of Trustees Of The Leland Stanford Junior University Isozyme-specific activators of protein kinase C methods and compositions
ES2210761T3 (es) * 1997-05-21 2004-07-01 The Board Of Trustees Of The Leland Stanford Junior University Composicion y procedimiento para mejorar el transporte a traves de las membranas biologicas.
US6025140A (en) * 1997-07-24 2000-02-15 Perseptive Biosystems, Inc. Membrane-permeable constructs for transport across a lipid membrane
US6258774B1 (en) * 1998-03-19 2001-07-10 University Of Medicine And Dentistry Of New Jersey Carrier for in vivo delivery of a therapeutic agent
US20030108539A1 (en) 2000-02-14 2003-06-12 Christophe Bonny Cell-permeable peptide inhibitors of the JNK signal transduction pathway
HK1053972A1 (zh) * 2000-02-16 2003-11-14 Northwestern University 聚甘氨酸胺基取代的阳离子寡聚合物肺表面活性剂
IL137290A0 (en) 2000-07-13 2001-07-24 Asher Eldad Ben An electronic circuit for reducing the danger of exposure to radiation from a transmitter
JP3710368B2 (ja) 2000-09-25 2005-10-26 シャープ株式会社 積層フィルムの製造方法
JP2005500002A (ja) * 2000-10-02 2005-01-06 エリゼク・ファーマシュウティカルズ・インコーポレイテッド 生物学的に活性な薬剤を細胞関門を越えて輸送するための組成物および方法
US20020168354A1 (en) * 2000-11-10 2002-11-14 Daria Mochly-Rosen psiepsilonRack peptide composition and method for protection against tissue damage due to ischemia
AU2002226061B2 (en) * 2001-01-18 2007-08-02 The Board Of Trustees Of The Leland Stanford Junior University Peptides for activation and inhibition of delta PKC
WO2002062396A2 (en) * 2001-02-08 2002-08-15 University Of Medicine And Dentistry Of New Jersey Enhanced oral and transcompartmental delivery of therapeutic or diagnostic agents using polymer conjugates
US20090075377A1 (en) * 2001-08-03 2009-03-19 Arbor Vita Corporation Molecular interactions in cells
EP1493748A1 (en) 2002-04-11 2005-01-05 Mochida Pharmaceutical Co., Ltd. Peptide chemically modified with polyethylene glycol
US7507711B2 (en) * 2002-04-22 2009-03-24 The Board Of Trustees Of The Leland Stanford Junior University Peptide inhibitors of protein kinase C
US6933275B2 (en) * 2002-05-01 2005-08-23 The Board Of Trustees Of The Leland Stanford Junior University Protein kinase C peptides for use in withdrawal
CN101804200A (zh) * 2002-11-22 2010-08-18 余芒 广谱抗病毒的治疗和预防
US20040175384A1 (en) * 2003-12-12 2004-09-09 Mohapatra Shyam S. Protein kinase C as a target for the treatment of respiratory syncytial virus
KR101130181B1 (ko) 2003-02-27 2012-03-28 예다 리서치 앤드 디벨럽먼트 캄파니 리미티드 인플루엔자 바이러스 감염의 치료 및 검출에 유용한 핵산분자, 폴리펩티드, 항체 및 이를 포함하는 조성물
WO2004084805A2 (en) * 2003-03-19 2004-10-07 The J. David Gladstone Institutes Acetylated tat polypeptides and methods of use thereof
ES2351976T3 (es) * 2003-04-29 2011-02-14 Avi Biopharma, Inc. Composiciones para mejorar el transporte y la eficacia antisentido de análogos de ácidos nucleicos en células.
CA2549052A1 (en) * 2003-12-11 2005-06-30 The Board Of Trustees Of The Leland Stanford Junior University Isozyme-specific antagonists of protein kinase c
JP2008508363A (ja) 2004-08-02 2008-03-21 ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー δプロテインキナーゼCの調節のためのペプチド配列
US7265092B2 (en) * 2004-09-30 2007-09-04 Kai Pharmaceuticals, Inc. Pharmaceutical formulation
JP4596391B2 (ja) * 2005-02-10 2010-12-08 国立大学法人大阪大学 細胞透過性ペプチド
CN101232895B (zh) * 2005-04-15 2014-06-04 亚利桑那癌症治疗公司 用于治疗转移性癌症的治疗肽
EP2194124A1 (en) * 2005-09-19 2010-06-09 Kai Pharmaceuticals, Inc. Protein kinase c peptide modulators of angiogenesis
US7579318B2 (en) * 2005-12-06 2009-08-25 Centre De La Recherche De La Scientifique Cell penetrating peptides for intracellular delivery of molecules
US7741290B2 (en) * 2006-06-01 2010-06-22 The Board of Trustee of The Leland Stanford Juinior University Method of preventing progression of hypertension-induced heart failure with PKC peptides
EP2069388A2 (en) * 2006-10-02 2009-06-17 The Board Of Trustees Of The Leland Stanford Junior University Peptides derived from the c2 domain of epsilon pkc, and use thereof
KR101552843B1 (ko) * 2006-11-16 2015-09-14 카이 파마슈티컬즈 부갑상선 기능항진증 및 고칼슘혈증 장애의 치료를 위한 폴리양이온성 칼슘 조절제 펩타이드
CN103524623A (zh) 2007-01-19 2014-01-22 凯制药公司 肽组合物的修饰以提高稳定性和递送效率
EP2124987A4 (en) * 2007-01-19 2012-05-02 Kai Pharmaceuticals Inc METHOD OF USE OF EPSILON HEMMER COMPOUNDS FOR PAIN LIFTING

Similar Documents

Publication Publication Date Title
JP2014224126A5 (enExample)
CY1122691T1 (el) Πρωτεϊνες δεσμευσης αλβουμινης ορου
RU2021134101A (ru) Модифицированная j-цепь
ES2691091T3 (es) Vacuna conjugada de péptido antigénico de WT1
JP2015514395A5 (enExample)
ES2616658T3 (es) Péptidos que mimetizan el factor de crecimiento y sus usos
JP2013172734A5 (enExample)
MX2020010806A (es) Peptidos anti-inflamatorios y usos de los mismos.
UA118167C2 (uk) Пептид та його застосування
MX2018007581A (es) Dominios variables de inmunoglobulina mejorados.
WO2015179635A3 (en) Ras inhibitory peptides and uses thereof
ES2676023T3 (es) Polipéptidos de IL-22 y proteínas de fusión de IL-22 Fc y métodos de uso
JP2015525217A5 (enExample)
JP2015513533A5 (enExample)
JP2014193892A5 (enExample)
MX393332B (es) Péptidos de tránsito dual para el direccionamiento a polipéptidos.
PH12014501083A1 (en) Anticancer fusion protein
MX377605B (es) Inmunoglobulina híbrida conteniendo un enlace no-peptidílico.
JP2015038108A5 (enExample)
PE20121033A1 (es) Produccion recombinante de peptidos
PH12013500715A1 (en) Anticancer fusion protein
FI3737399T3 (fi) ATF5-peptidivariantit ja niiden käytöt
JP2014525439A5 (enExample)
CU24609B1 (es) Proteína de fusión que comprende una proteína de subunidad de ferritina monomérica unida a una proteína de dominio alfa 3 de mic
JP2010265269A5 (enExample)