JP2014224126A5 - - Google Patents

Download PDF

Info

Publication number
JP2014224126A5
JP2014224126A5 JP2014143781A JP2014143781A JP2014224126A5 JP 2014224126 A5 JP2014224126 A5 JP 2014224126A5 JP 2014143781 A JP2014143781 A JP 2014143781A JP 2014143781 A JP2014143781 A JP 2014143781A JP 2014224126 A5 JP2014224126 A5 JP 2014224126A5
Authority
JP
Japan
Prior art keywords
peptide
composition
carrier
group
cargo
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2014143781A
Other languages
English (en)
Japanese (ja)
Other versions
JP2014224126A (ja
JP5937643B2 (ja
Filing date
Publication date
Application filed filed Critical
Publication of JP2014224126A publication Critical patent/JP2014224126A/ja
Publication of JP2014224126A5 publication Critical patent/JP2014224126A5/ja
Application granted granted Critical
Publication of JP5937643B2 publication Critical patent/JP5937643B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2014143781A 2007-01-19 2014-07-14 ペプチド組成物の安定性および送達効率を上昇させるための修飾方法 Active JP5937643B2 (ja)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US88141907P 2007-01-19 2007-01-19
US60/881,419 2007-01-19
US94528507P 2007-06-20 2007-06-20
US60/945,285 2007-06-20

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2009546577A Division JP2010516707A (ja) 2007-01-19 2008-01-22 ペプチド組成物の安定性および送達効率を上昇させるための修飾方法

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2016096016A Division JP2016147905A (ja) 2007-01-19 2016-05-12 ペプチド組成物の安定性および送達効率を上昇させるための修飾方法

Publications (3)

Publication Number Publication Date
JP2014224126A JP2014224126A (ja) 2014-12-04
JP2014224126A5 true JP2014224126A5 (enExample) 2015-07-16
JP5937643B2 JP5937643B2 (ja) 2016-06-22

Family

ID=39636771

Family Applications (7)

Application Number Title Priority Date Filing Date
JP2009546577A Ceased JP2010516707A (ja) 2007-01-19 2008-01-22 ペプチド組成物の安定性および送達効率を上昇させるための修飾方法
JP2014143781A Active JP5937643B2 (ja) 2007-01-19 2014-07-14 ペプチド組成物の安定性および送達効率を上昇させるための修飾方法
JP2016096016A Pending JP2016147905A (ja) 2007-01-19 2016-05-12 ペプチド組成物の安定性および送達効率を上昇させるための修飾方法
JP2018058012A Pending JP2018111717A (ja) 2007-01-19 2018-03-26 ペプチド組成物の安定性および送達効率を上昇させるための修飾方法
JP2021036134A Pending JP2021098725A (ja) 2007-01-19 2021-03-08 ペプチド組成物の安定性および送達効率を上昇させるための修飾方法
JP2023049966A Pending JP2023078424A (ja) 2007-01-19 2023-03-27 ペプチド組成物の安定性および送達効率を上昇させるための修飾方法
JP2025170793A Pending JP2025185093A (ja) 2007-01-19 2025-10-09 ペプチド組成物の安定性および送達効率を上昇させるための修飾方法

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP2009546577A Ceased JP2010516707A (ja) 2007-01-19 2008-01-22 ペプチド組成物の安定性および送達効率を上昇させるための修飾方法

Family Applications After (5)

Application Number Title Priority Date Filing Date
JP2016096016A Pending JP2016147905A (ja) 2007-01-19 2016-05-12 ペプチド組成物の安定性および送達効率を上昇させるための修飾方法
JP2018058012A Pending JP2018111717A (ja) 2007-01-19 2018-03-26 ペプチド組成物の安定性および送達効率を上昇させるための修飾方法
JP2021036134A Pending JP2021098725A (ja) 2007-01-19 2021-03-08 ペプチド組成物の安定性および送達効率を上昇させるための修飾方法
JP2023049966A Pending JP2023078424A (ja) 2007-01-19 2023-03-27 ペプチド組成物の安定性および送達効率を上昇させるための修飾方法
JP2025170793A Pending JP2025185093A (ja) 2007-01-19 2025-10-09 ペプチド組成物の安定性および送達効率を上昇させるための修飾方法

Country Status (8)

Country Link
US (7) US8067532B2 (enExample)
EP (2) EP2109619B1 (enExample)
JP (7) JP2010516707A (enExample)
KR (4) KR102274003B1 (enExample)
CN (3) CN101675067B (enExample)
AU (1) AU2008206077A1 (enExample)
CA (2) CA2675665C (enExample)
WO (1) WO2008089491A2 (enExample)

Families Citing this family (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8168181B2 (en) 2006-02-13 2012-05-01 Alethia Biotherapeutics, Inc. Methods of impairing osteoclast differentiation using antibodies that bind siglec-15
JP5173838B2 (ja) 2006-02-13 2013-04-03 アレシア・バイオセラピューティクス・インコーポレーテッド 骨リモデリングのプロセスと関係があるポリヌクレオチドおよびポリペプチド配列
JP5645408B2 (ja) 2006-11-16 2014-12-24 カイ ファーマシューティカルズ インコーポレーティッド 副甲状腺機能亢進症および高カルシウム血症性障害の治療のためのポリカチオン性カルシウムモジュレーターペプチド
US8067532B2 (en) * 2007-01-19 2011-11-29 Kai Pharmaceuticals, Inc. Modifications of peptide compositions to increase stability and delivery efficiency
US20090318351A1 (en) * 2008-03-12 2009-12-24 Kevin Grimes Method of treating acute st-elevation myocardial infarction with a delta pkc antagonist
US20100311671A1 (en) * 2009-03-25 2010-12-09 Kai Pharmaceuticals Transdermal delivery of pkc modulatory peptides through microporated skin
EP2459208B1 (en) 2009-07-29 2016-09-28 Kai Pharmaceuticals, Inc. Therapeutic agents for reducing parathyroid hormone levels
PT2717896T (pt) 2011-06-08 2016-12-23 Kai Pharmaceuticals Inc Agentes terapêuticos para a regulação do fósforo sérico
WO2013128003A1 (en) * 2012-03-01 2013-09-06 Novo Nordisk A/S N-terminally modified oligopeptides and uses thereof
AU2013293062A1 (en) 2012-07-19 2014-07-24 Alethia Biotherapeutics Inc. Anti-Siglec-15 antibodies
EP2986306A4 (en) 2013-04-18 2016-12-07 Armo Biosciences Inc METHOD FOR USE OF INTERLEUKIN-10 FOR THE TREATMENT OF ILLNESSES AND SUFFERING
CA2914837A1 (en) 2013-06-17 2014-12-24 Armo Biosciences, Inc. Method for assessing protein identity and stability
PE20160549A1 (es) * 2013-06-28 2016-06-15 Amgen Inc Formulacion liquida estable de etelcalcetida (amg 416)
US10010588B2 (en) 2013-08-30 2018-07-03 Armo Biosciences, Inc. Methods of using pegylated interleukin-10 for treating hyperlipidemia
NZ718962A (en) 2013-10-28 2019-12-20 Ngm Biopharmaceuticals Inc Cancer models and associated methods
KR20160079114A (ko) 2013-11-11 2016-07-05 아르모 바이오사이언시스 인코포레이티드 질환 및 장애를 치료하기 위한 인터류킨-10을 사용하는 방법
WO2015187295A2 (en) 2014-06-02 2015-12-10 Armo Biosciences, Inc. Methods of lowering serum cholesterol
EP3206713A4 (en) 2014-10-14 2018-06-27 Armo Biosciences, Inc. Interleukin-15 compositions and uses thereof
AU2015336101A1 (en) 2014-10-22 2017-04-20 Armo Biosciences, Inc. Methods of using interleukin-10 for treating diseases and disorders
US10618970B2 (en) 2015-02-03 2020-04-14 Armo Biosciences, Inc. Method of treating cancer with IL-10 and antibodies that induce ADCC
US10456475B2 (en) 2015-02-03 2019-10-29 Kennsaw State University Research and Service Foundation, Inc. Cell penetrating protein adaptor molecules and their application in research and medicine
WO2016191587A1 (en) 2015-05-28 2016-12-01 Armo Biosciences, Inc. Pegylated interleukin-10 for use in treating cancer
HK1245671A1 (zh) 2015-05-29 2018-08-31 Armo Biosciences, Inc. 使用白细胞介素-10治疗疾病和病症的方法
US10435446B2 (en) 2015-06-03 2019-10-08 Kennesaw State University Research and Service Foundation Inc. Cell penetrating protein adaptor molecules and their application in research and medicine
CA2995120A1 (en) 2015-08-25 2017-03-02 Armo Biosciences, Inc. Methods of using interleukin-10 for treating diseases and disorders
BR112018011096A2 (pt) * 2015-12-02 2018-12-04 Inst Nat De La Rech Agronomique Inra novos peptídeos que têm atividade antimicrobiana e nova enzima capaz de converter resíduo de configuração l em aminoácido de configuração d em um peptídeo
EP3411387A4 (en) 2016-02-03 2019-12-04 Kennesaw State University Research And Services Foundation Inc. SIGNAL MOLECULES AS A CELL PENETRANT
WO2018035046A1 (en) 2016-08-15 2018-02-22 President And Fellows Of Harvard College Treating infections using idsd from proteus mirabilis
KR101772449B1 (ko) * 2016-12-27 2017-08-30 주식회사 하이센스바이오 신규한 펩타이드
CA3087881A1 (en) 2017-01-17 2018-07-26 Michael David FORREST Therapeutic inhibitors of the reverse mode of atp synthase
CA3099077A1 (en) 2017-07-13 2019-01-17 Michael David FORREST Therapeutic modulators of the reverse mode of atp synthase
CN111315398A (zh) 2017-11-10 2020-06-19 阿尔莫生物科技股份有限公司 白介素-10与免疫检查点途径抑制剂的组合的组合物和使用方法
MX2020010071A (es) * 2018-03-29 2021-01-08 Contrafect Corp Polipeptidos anti-microbianos, derivados de bacteriofago, y sus usos contra bacterias gram negativas.
JP7097465B2 (ja) 2018-06-19 2022-07-07 アルモ・バイオサイエンシーズ・インコーポレイテッド キメラ抗原受容体細胞療法と併用するｉｌ－１０剤の組成およびその使用方法
US10905738B2 (en) * 2018-07-05 2021-02-02 Biozeus Desenvolvimento De Produtos Biofarmacêuticos Synthetic peptides, prodrugs, pharmaceutical compositions and uses
GB201903873D0 (en) * 2019-03-21 2019-05-08 Univ Nottingham Enhanced transfection
WO2021002408A1 (ja) 2019-07-02 2021-01-07 Ａｇｃ株式会社 ペプチド及びその製造方法
EP4058466A1 (en) 2019-11-13 2022-09-21 Amunix Pharmaceuticals, Inc. Barcoded xten polypeptides and compositions thereof, and methods for making and using the same
WO2021195254A1 (en) * 2020-03-24 2021-09-30 Young Therapeutics, Llc Protein kinase c modulators
US20250325469A1 (en) 2021-01-24 2025-10-23 Michael David FORREST Inhibitors of atp synthase - cosmetic and therapeutic uses
WO2023048236A1 (ja) 2021-09-22 2023-03-30 Ａｇｃ株式会社 ペプチド
KR102380732B1 (ko) 2021-09-23 2022-04-04 엘이솔루션 주식회사 축산분뇨처리시스템
US20250082777A1 (en) 2022-01-10 2025-03-13 Sana Biotechnology, Inc. Methods of ex vivo dosing and administration of lipid particles or viral vectors and related systems and uses
WO2023193015A1 (en) 2022-04-01 2023-10-05 Sana Biotechnology, Inc. Cytokine receptor agonist and viral vector combination therapies
WO2025135179A1 (ja) 2023-12-22 2025-06-26 Ａｇｃ株式会社 蛍光増強剤

Family Cites Families (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US615977A (en) * 1898-12-13 Car-fender
US6316003B1 (en) 1989-12-21 2001-11-13 Whitehead Institute For Biomedical Research Tat-derived transport polypeptides
US5783405A (en) 1994-02-01 1998-07-21 Terrapin Technologies, Inc. Rapid screening method for effectors of signal transduction
US5935803A (en) * 1994-02-01 1999-08-10 Terrapin Technologies, Inc. Methods to identify immunomodulators using cognate interaction of PKC-theta
US5776716A (en) * 1994-02-01 1998-07-07 Terrapin Technologies, Inc. Methods for identifying agents which block the interaction of fyn with PKC-theta, and uses thereof
US6165977A (en) 1996-10-18 2000-12-26 Board Of Trustees Of The Leland Stanford Junior University Isozyme-specific activators of protein kinase C methods and compositions
ES2210761T3 (es) * 1997-05-21 2004-07-01 The Board Of Trustees Of The Leland Stanford Junior University Composicion y procedimiento para mejorar el transporte a traves de las membranas biologicas.
AU741546B2 (en) 1997-07-24 2001-12-06 Perseptive Biosystems, Inc. Conjugates of transporter peptides and nucleic acid analogs, and their use
US6258774B1 (en) * 1998-03-19 2001-07-10 University Of Medicine And Dentistry Of New Jersey Carrier for in vivo delivery of a therapeutic agent
US20030108539A1 (en) 2000-02-14 2003-06-12 Christophe Bonny Cell-permeable peptide inhibitors of the JNK signal transduction pathway
EP1267904A4 (en) * 2000-02-16 2006-02-08 Univ Northwestern POLYPEPTOIDE PULMONARY SURFACTANTS
IL137290A0 (en) 2000-07-13 2001-07-24 Asher Eldad Ben An electronic circuit for reducing the danger of exposure to radiation from a transmitter
JP3710368B2 (ja) 2000-09-25 2005-10-26 シャープ株式会社 積層フィルムの製造方法
IL155204A0 (en) * 2000-10-02 2003-11-23 Arizeke Pharmaceuticals Inc Compositions and methods for the transport of biologically active agents across cellular barriers
US20020168354A1 (en) 2000-11-10 2002-11-14 Daria Mochly-Rosen psiepsilonRack peptide composition and method for protection against tissue damage due to ischemia
CA2434643C (en) 2001-01-18 2013-10-29 The Board Of Trustees Of The Leland Stanford Junior University Peptides for activation and inhibition of.delta.pkc
AU2002240312A1 (en) * 2001-02-08 2002-08-19 Pankaj Paranjp Enhanced oral and transcompartmental delivery of therapeutic or diagnostic agents using polymer conjugates
US20090075377A1 (en) * 2001-08-03 2009-03-19 Arbor Vita Corporation Molecular interactions in cells
WO2003084985A1 (fr) * 2002-04-11 2003-10-16 Mochida Pharmaceutical Co., Ltd. Peptide chimiquement modifie a l'aide de polyethyleneglycol
JP2005523326A (ja) 2002-04-22 2005-08-04 ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティ プロテインキナーゼｃのペプチドインヒビター
US6933275B2 (en) 2002-05-01 2005-08-23 The Board Of Trustees Of The Leland Stanford Junior University Protein kinase C peptides for use in withdrawal
AU2003294401C1 (en) * 2002-11-22 2008-09-18 Ansun Biopharma, Inc. Broad spectrum anti-viral therapeutics and prophylaxis
US20040175384A1 (en) * 2003-12-12 2004-09-09 Mohapatra Shyam S. Protein kinase C as a target for the treatment of respiratory syncytial virus
AU2004215133B2 (en) 2003-02-27 2010-10-14 Yeda Research And Development Co. Ltd. Nucleic acid molecules, polypeptides, antibodies and compositions containing same useful for treating and detecting influenza virus infection
WO2004084805A2 (en) * 2003-03-19 2004-10-07 The J. David Gladstone Institutes Acetylated tat polypeptides and methods of use thereof
AU2004235396B2 (en) * 2003-04-29 2010-11-25 Sarepta Therapeutics, Inc. Compositions for enhancing transport and antisense efficacy of nucleic acid analog into cells
US20050187156A1 (en) * 2003-12-11 2005-08-25 Daria Mochly-Rosen Isozyme-specific antagonists of protein kinase C
EP1784483A2 (en) 2004-08-02 2007-05-16 The Board Of Trustees Of The Leland Stanford Junior University Peptide sequence for modulation of delta protein kinase c
US7265092B2 (en) * 2004-09-30 2007-09-04 Kai Pharmaceuticals, Inc. Pharmaceutical formulation
JP4596391B2 (ja) * 2005-02-10 2010-12-08 国立大学法人大阪大学 細胞透過性ペプチド
JP5116663B2 (ja) * 2005-04-15 2013-01-09 アリゾナ バイオメディカル リサーチ コミッション 転移癌の処置のための治療用ペプチド
WO2007035782A2 (en) * 2005-09-19 2007-03-29 Kai Pharmaceuticals, Inc. Protein kinase c peptide modulators of angiogenesis
US7579318B2 (en) * 2005-12-06 2009-08-25 Centre De La Recherche De La Scientifique Cell penetrating peptides for intracellular delivery of molecules
US7741290B2 (en) * 2006-06-01 2010-06-22 The Board of Trustee of The Leland Stanford Juinior University Method of preventing progression of hypertension-induced heart failure with PKC peptides
AU2007305268A1 (en) * 2006-10-02 2008-04-10 The Board Of Trustees Of The Leland Stanford Junior University Peptides derived from the C2 domain of epsilon PKC, and use thereof
JP5645408B2 (ja) * 2006-11-16 2014-12-24 カイ ファーマシューティカルズ インコーポレーティッド 副甲状腺機能亢進症および高カルシウム血症性障害の治療のためのポリカチオン性カルシウムモジュレーターペプチド
US8067532B2 (en) * 2007-01-19 2011-11-29 Kai Pharmaceuticals, Inc. Modifications of peptide compositions to increase stability and delivery efficiency
US8017583B2 (en) * 2007-01-19 2011-09-13 Kai Pharmaceuticals, Inc. Methods of use of epsilon inhibitor compounds for the attenuation of pain

Similar Documents

Publication Publication Date Title
CY1122691T1 (el) Πρωτεϊνες δεσμευσης αλβουμινης ορου
NZ629394A (en) Synthetic brassica-derived chloroplast transit peptides
ES2691091T3 (es) Vacuna conjugada de péptido antigénico de WT1
JP2015514395A5 (enExample)
ES2616658T3 (es) Péptidos que mimetizan el factor de crecimiento y sus usos
JP2013172734A5 (enExample)
UA118167C2 (uk) Пептид та його застосування
MX2023010731A (es) Dominios variables de inmunoglobulina mejorados.
CL2013003416A1 (es) Secuencia de peptidos quiméricos que comprende dsspl o dasph composiciones , usos y metodo para mejorar metabolismo de glucosa.
MX2018000697A (es) Peptidos anti-inflamatorios y usos de los mismos.
PE20190352A1 (es) Proteinas de fusion gdf 15 y usos de estas
WO2015179635A3 (en) Ras inhibitory peptides and uses thereof
ES2676023T3 (es) Polipéptidos de IL-22 y proteínas de fusión de IL-22 Fc y métodos de uso
JP2015525217A5 (enExample)
JP2015513533A5 (enExample)
JP2014193892A5 (enExample)
PL393578A1 (pl) Przeciwnowotworowe białko fuzyjne
NZ609216A (en) Anticancer fusion protein
FI3737399T3 (fi) ATF5-peptidivariantit ja niiden käytöt
NZ629843A (en) Identification of channelrhodopsin-2 (chop2) mutations and methods of use
WO2015185758A3 (en) Preparation comprising factor viii and von willebrand factor peptides
JP2014525439A5 (enExample)
CU24609B1 (es) Proteína de fusión que comprende una proteína de subunidad de ferritina monomérica unida a una proteína de dominio alfa 3 de mic
JP2010265269A5 (enExample)
IN2014DN09367A (enExample)