JP2014193892A5 - - Google Patents
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- JP2014193892A5 JP2014193892A5 JP2014101360A JP2014101360A JP2014193892A5 JP 2014193892 A5 JP2014193892 A5 JP 2014193892A5 JP 2014101360 A JP2014101360 A JP 2014101360A JP 2014101360 A JP2014101360 A JP 2014101360A JP 2014193892 A5 JP2014193892 A5 JP 2014193892A5
- Authority
- JP
- Japan
- Prior art keywords
- affinity chromatography
- ligand
- amino acid
- domains
- spa
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 238000001042 affinity chromatography Methods 0.000 claims 16
- 239000003446 ligand Substances 0.000 claims 14
- 235000001014 amino acid Nutrition 0.000 claims 10
- 150000001413 amino acids Chemical class 0.000 claims 10
- 239000012504 chromatography matrix Substances 0.000 claims 6
- 230000035772 mutation Effects 0.000 claims 6
- 230000037430 deletion Effects 0.000 claims 4
- 238000012217 deletion Methods 0.000 claims 4
- 241000191940 Staphylococcus Species 0.000 claims 3
- 235000018102 proteins Nutrition 0.000 claims 3
- 102000004169 proteins and genes Human genes 0.000 claims 3
- 108090000623 proteins and genes Proteins 0.000 claims 3
- 239000004471 Glycine Substances 0.000 claims 1
- DHMQDGOQFOQNFH-UHFFFAOYSA-N Glycine Natural products NCC(O)=O DHMQDGOQFOQNFH-UHFFFAOYSA-N 0.000 claims 1
- 239000004472 Lysine Substances 0.000 claims 1
- KDXKERNSBIXSRK-UHFFFAOYSA-N Lysine Natural products NCCCCC(N)C(O)=O KDXKERNSBIXSRK-UHFFFAOYSA-N 0.000 claims 1
- 235000004279 alanine Nutrition 0.000 claims 1
- 238000013467 fragmentation Methods 0.000 claims 1
- 238000006062 fragmentation reaction Methods 0.000 claims 1
- 239000007787 solid Substances 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161494701P | 2011-06-08 | 2011-06-08 | |
| US61/494,701 | 2011-06-08 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012124067A Division JP5756428B2 (ja) | 2011-06-08 | 2012-05-31 | 新規なスタフィロコッカス・アウレウス（Ｓｔａｐｈｙｌｏｃｏｃｃｕｓａｕｒｅｕｓ）プロテインＡベースのリガンドを含むクロマトグラフィーマトリックス |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016140214A Division JP6189493B2 (ja) | 2011-06-08 | 2016-07-15 | 新規なスタフィロコッカス・アウレウス（Ｓｔａｐｈｙｌｏｃｏｃｃｕｓ ａｕｒｅｕｓ）プロテインＡベースのリガンドを含むクロマトグラフィーマトリックス |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014193892A JP2014193892A (ja) | 2014-10-09 |
| JP2014193892A5 true JP2014193892A5 (OSRAM) | 2015-07-16 |
| JP6018120B2 JP6018120B2 (ja) | 2016-11-02 |
Family
ID=46229293
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012124067A Active JP5756428B2 (ja) | 2011-06-08 | 2012-05-31 | 新規なスタフィロコッカス・アウレウス（Ｓｔａｐｈｙｌｏｃｏｃｃｕｓａｕｒｅｕｓ）プロテインＡベースのリガンドを含むクロマトグラフィーマトリックス |
| JP2014101360A Active JP6018120B2 (ja) | 2011-06-08 | 2014-05-15 | 新規なスタフィロコッカス・アウレウス（Ｓｔａｐｈｙｌｏｃｏｃｃｕｓａｕｒｅｕｓ）プロテインＡベースのリガンドを含むクロマトグラフィーマトリックス |
| JP2016140214A Active JP6189493B2 (ja) | 2011-06-08 | 2016-07-15 | 新規なスタフィロコッカス・アウレウス（Ｓｔａｐｈｙｌｏｃｏｃｃｕｓ ａｕｒｅｕｓ）プロテインＡベースのリガンドを含むクロマトグラフィーマトリックス |
| JP2017148843A Active JP6586131B2 (ja) | 2011-06-08 | 2017-08-01 | 新規なスタフィロコッカス・アウレウス（Ｓｔａｐｈｙｌｏｃｏｃｃｕｓ ａｕｒｅｕｓ）プロテインＡベースのリガンドを含むクロマトグラフィーマトリックス |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012124067A Active JP5756428B2 (ja) | 2011-06-08 | 2012-05-31 | 新規なスタフィロコッカス・アウレウス（Ｓｔａｐｈｙｌｏｃｏｃｃｕｓａｕｒｅｕｓ）プロテインＡベースのリガンドを含むクロマトグラフィーマトリックス |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016140214A Active JP6189493B2 (ja) | 2011-06-08 | 2016-07-15 | 新規なスタフィロコッカス・アウレウス（Ｓｔａｐｈｙｌｏｃｏｃｃｕｓ ａｕｒｅｕｓ）プロテインＡベースのリガンドを含むクロマトグラフィーマトリックス |
| JP2017148843A Active JP6586131B2 (ja) | 2011-06-08 | 2017-08-01 | 新規なスタフィロコッカス・アウレウス（Ｓｔａｐｈｙｌｏｃｏｃｃｕｓ ａｕｒｅｕｓ）プロテインＡベースのリガンドを含むクロマトグラフィーマトリックス |
Country Status (13)
| Country | Link |
|---|---|
| US (5) | US8754196B2 (OSRAM) |
| EP (2) | EP2532672B1 (OSRAM) |
| JP (4) | JP5756428B2 (OSRAM) |
| KR (3) | KR101464040B1 (OSRAM) |
| CN (2) | CN102895960B (OSRAM) |
| AU (3) | AU2012366229C1 (OSRAM) |
| DK (2) | DK2532672T3 (OSRAM) |
| ES (2) | ES2710204T3 (OSRAM) |
| IL (2) | IL229774A (OSRAM) |
| RU (2) | RU2644680C1 (OSRAM) |
| SG (3) | SG186552A1 (OSRAM) |
| TW (3) | TWI596108B (OSRAM) |
| WO (1) | WO2013109302A2 (OSRAM) |
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| US8877688B2 (en) | 2007-09-14 | 2014-11-04 | Adimab, Llc | Rationally designed, synthetic antibody libraries and uses therefor |
| US8592555B2 (en) | 2008-08-11 | 2013-11-26 | Emd Millipore Corporation | Immunoglobulin-binding proteins with improved specificity |
| SG195555A1 (en) | 2008-12-24 | 2013-12-30 | Emd Millipore Corp | Caustic stable chromatography ligands |
| SG186552A1 (en) * | 2011-06-08 | 2013-01-30 | Emd Millipore Corp | Chromatography matrices including novel staphylococcus aureus protein a based ligands |
| WO2013081540A1 (en) * | 2011-11-30 | 2013-06-06 | Ge Healthcare Bio-Sciences Ab | Affinity chromatography matrix |
| EP2682168A1 (en) | 2012-07-02 | 2014-01-08 | Millipore Corporation | Purification of biological molecules |
| JP6182210B2 (ja) | 2012-06-29 | 2017-08-16 | イー・エム・デイー・ミリポア・コーポレイシヨン | タンパク質精製プロセス中のウイルスの不活性化方法 |
| MY178616A (en) | 2012-09-17 | 2020-10-19 | Grace W R & Co | Chromatography media and devices |
| CN104768536B (zh) | 2012-09-17 | 2019-03-29 | 格雷斯公司 | 官能化微粒状载体材料和其制备和使用方法 |
| ES2735354T3 (es) | 2013-03-14 | 2019-12-18 | Emd Millipore Corp | Métodos para aumentar la pureza de proteínas utilizando la cromatografía basada en proteína A |
| CN105377880B (zh) * | 2013-07-10 | 2020-08-07 | 通用电气医疗集团生物工艺研发股份公司 | 突变的免疫球蛋白结合多肽 |
| ES2737078T3 (es) * | 2013-09-04 | 2020-01-10 | Emd Millipore Corp | Cromatografía de Proteína A |
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| PL3137209T3 (pl) | 2014-05-02 | 2023-01-02 | W.R. Grace & Co. - Conn. | Funkcjonalizowany materiał nośnikowy i sposoby wytwarzania oraz stosowania funkcjonalizowanego materiału nośnikowego |
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