DK3253785T3 - Hidtil ukendte egfr-bindingsproteiner - Google Patents
Hidtil ukendte egfr-bindingsproteiner Download PDFInfo
- Publication number
- DK3253785T3 DK3253785T3 DK16702945.3T DK16702945T DK3253785T3 DK 3253785 T3 DK3253785 T3 DK 3253785T3 DK 16702945 T DK16702945 T DK 16702945T DK 3253785 T3 DK3253785 T3 DK 3253785T3
- Authority
- DK
- Denmark
- Prior art keywords
- ended
- binding proteins
- egfr binding
- egfr
- proteins
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2863—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/31—Fusion polypeptide fusions, other than Fc, for prolonged plasma life, e.g. albumin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/95—Fusion polypeptide containing a motif/fusion for degradation (ubiquitin fusions, PEST sequence)
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Cell Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP15154159 | 2015-02-06 | ||
PCT/EP2016/052408 WO2016124702A1 (en) | 2015-02-06 | 2016-02-04 | Novel egfr binding proteins |
Publications (1)
Publication Number | Publication Date |
---|---|
DK3253785T3 true DK3253785T3 (da) | 2019-07-08 |
Family
ID=52446320
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK16702945.3T DK3253785T3 (da) | 2015-02-06 | 2016-02-04 | Hidtil ukendte egfr-bindingsproteiner |
Country Status (6)
Country | Link |
---|---|
US (1) | US10858405B2 (da) |
EP (1) | EP3253785B1 (da) |
JP (1) | JP6738340B2 (da) |
CA (1) | CA2975362A1 (da) |
DK (1) | DK3253785T3 (da) |
WO (1) | WO2016124702A1 (da) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN107922483B (zh) | 2015-07-16 | 2021-07-30 | 纳维格蛋白质有限公司 | 新型免疫球蛋白结合蛋白及其在亲和纯化中的用途 |
JP2018520675A (ja) | 2015-07-20 | 2018-08-02 | ナフィゴ プロテインズ ゲゼルシャフト ミット ベシュレンクテル ハフツングNavigo Proteins GmbH | ジユビキチン変異タンパク質をベースとした新規結合タンパク質及びその生成方法 |
WO2017191252A1 (en) | 2016-05-04 | 2017-11-09 | Navigo Proteins Gmbh | Targeted compounds for the site-specific coupling of chemical moieties comprising a peptide linker |
WO2018029158A1 (en) | 2016-08-11 | 2018-02-15 | Repligen Corporation | Alkaline stable fc—binding proteins for affinity chromatography |
EP3706804B1 (en) | 2017-11-07 | 2022-02-23 | Navigo Proteins GmbH | Fusion proteins with specificity for ed-b and long serum half-life for diagnosis or treatment of cancer |
US20220127312A1 (en) * | 2018-12-18 | 2022-04-28 | Navigo Proteins Gmbh | Novel folr1 specific binding proteins for cancer diagnosis and treatment |
SG11202110940YA (en) * | 2019-04-10 | 2021-10-28 | Navigo Proteins Gmbh | Novel psma specific binding proteins for cancer diagnosis and treatment |
EP4370529A1 (en) * | 2021-07-13 | 2024-05-22 | Navigo Proteins Gmbh | Affinity ligands for the purification and detection of ubiquitin muteins |
Family Cites Families (51)
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BE679856A (da) | 1965-05-06 | 1966-10-03 | ||
US4873192A (en) | 1987-02-17 | 1989-10-10 | The United States Of America As Represented By The Department Of Health And Human Services | Process for site specific mutagenesis without phenotypic selection |
SE9103701D0 (sv) | 1991-12-13 | 1991-12-13 | Kabi Pharmacia Ab | Apolipoprotein |
AU7142796A (en) | 1995-10-02 | 1997-04-28 | Erasmus University Rotterdam | Diagnosis method and reagents |
CA2235223A1 (en) | 1995-10-30 | 1997-05-09 | Massachusetts Institute Of Technology | Rationally designed polysaccharide lyases derived from heparinase i |
US5789166A (en) | 1995-12-08 | 1998-08-04 | Stratagene | Circular site-directed mutagenesis |
GB9610967D0 (en) | 1996-05-24 | 1996-07-31 | Cambridge Antibody Tech | Specific binding members,materials and methods |
FR2761689B1 (fr) | 1997-04-02 | 1999-06-25 | Transgene Sa | Fibre adenovirale modifiee et adenovirus cibles |
ES2209145T5 (es) | 1997-05-28 | 2009-10-30 | Crescendo Biologics Ltd. | Complejos de ribosomas como particulas de seleccion para el desarrollo in vitro y evolucion de proteinas. |
JP3614866B2 (ja) | 1997-06-12 | 2005-01-26 | リサーチ コーポレイション テクノロジーズ,インコーポレイティド | 人工抗体ポリペプチド |
DE19742706B4 (de) | 1997-09-26 | 2013-07-25 | Pieris Proteolab Ag | Lipocalinmuteine |
US20030045681A1 (en) | 1998-05-11 | 2003-03-06 | Anthony J. Zelano | Specific binding molecules for scintigraphy, conjugates containing them and therapeutic method for treatment of angiogenesis |
TWI259837B (en) | 1998-05-11 | 2006-08-11 | Eidgenossische Tech Hochscule | Specific binding molecules for scintigraphy, conjugates containing them and therapeutic method for treatment of angiogenesis |
DE19932688B4 (de) | 1999-07-13 | 2009-10-08 | Scil Proteins Gmbh | Design von Beta-Faltblatt-Proteinen des gamma-II-kristallins antikörperähnlichen |
JP2003524018A (ja) | 2000-02-24 | 2003-08-12 | アイトゲネーシシェ テクニシェ ホッホシューレ チューリッヒ | フィブロネクチンのed‐bドメインに特異的な抗体、前記抗体を含む複合体、および血管形成を検出および治療するためのその使用 |
US8623373B2 (en) | 2000-02-24 | 2014-01-07 | Philogen S.P.A. | Compositions and methods for treatment of angiogenesis in pathological lesions |
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WO2005044845A2 (en) | 2003-11-04 | 2005-05-19 | Yale University | Protein binding miniature proteins |
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KR102236367B1 (ko) | 2013-07-26 | 2021-04-05 | 삼성전자주식회사 | DARPin을 포함하는 이중 특이 키메라 단백질 |
WO2016124670A1 (en) | 2015-02-06 | 2016-08-11 | Scil Proteins Gmbh | Novel binding proteins comprising a ubiquitin mutein and antibodies or antibody fragments |
CN107922483B (zh) | 2015-07-16 | 2021-07-30 | 纳维格蛋白质有限公司 | 新型免疫球蛋白结合蛋白及其在亲和纯化中的用途 |
JP6881760B2 (ja) | 2015-07-20 | 2021-06-02 | ナフィゴ プロテインズ ゲゼルシャフト ミット ベシュレンクテル ハフツングNavigo Proteins GmbH | ジユビキチン変異タンパク質に基づくHer2結合タンパク質 |
JP2018520675A (ja) | 2015-07-20 | 2018-08-02 | ナフィゴ プロテインズ ゲゼルシャフト ミット ベシュレンクテル ハフツングNavigo Proteins GmbH | ジユビキチン変異タンパク質をベースとした新規結合タンパク質及びその生成方法 |
WO2017191252A1 (en) | 2016-05-04 | 2017-11-09 | Navigo Proteins Gmbh | Targeted compounds for the site-specific coupling of chemical moieties comprising a peptide linker |
WO2018029158A1 (en) | 2016-08-11 | 2018-02-15 | Repligen Corporation | Alkaline stable fc—binding proteins for affinity chromatography |
-
2016
- 2016-02-04 CA CA2975362A patent/CA2975362A1/en active Pending
- 2016-02-04 EP EP16702945.3A patent/EP3253785B1/en active Active
- 2016-02-04 WO PCT/EP2016/052408 patent/WO2016124702A1/en active Application Filing
- 2016-02-04 DK DK16702945.3T patent/DK3253785T3/da active
- 2016-02-04 US US15/548,976 patent/US10858405B2/en active Active
- 2016-02-04 JP JP2017541016A patent/JP6738340B2/ja active Active
Also Published As
Publication number | Publication date |
---|---|
US10858405B2 (en) | 2020-12-08 |
CA2975362A1 (en) | 2016-08-11 |
US20180030098A1 (en) | 2018-02-01 |
EP3253785B1 (en) | 2019-04-10 |
EP3253785A1 (en) | 2017-12-13 |
JP6738340B2 (ja) | 2020-08-12 |
WO2016124702A1 (en) | 2016-08-11 |
JP2018505675A (ja) | 2018-03-01 |
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