|
US7622296B2
(en)
|
2004-05-28 |
2009-11-24 |
Wafergen, Inc. |
Apparatus and method for multiplex analysis
|
|
DE602005009324D1
(de)
|
2005-04-06 |
2008-10-09 |
Maurice Stroun |
Methode zur Krebsdiagnose mittels Nachweis von DNA und RNA im Kreislauf
|
|
US20100130369A1
(en)
*
|
2007-04-23 |
2010-05-27 |
Advanced Liquid Logic, Inc. |
Bead-Based Multiplexed Analytical Methods and Instrumentation
|
|
US8748103B2
(en)
|
2008-11-07 |
2014-06-10 |
Sequenta, Inc. |
Monitoring health and disease status using clonotype profiles
|
|
US9506119B2
(en)
|
2008-11-07 |
2016-11-29 |
Adaptive Biotechnologies Corp. |
Method of sequence determination using sequence tags
|
|
US8628927B2
(en)
|
2008-11-07 |
2014-01-14 |
Sequenta, Inc. |
Monitoring health and disease status using clonotype profiles
|
|
US9365901B2
(en)
|
2008-11-07 |
2016-06-14 |
Adaptive Biotechnologies Corp. |
Monitoring immunoglobulin heavy chain evolution in B-cell acute lymphoblastic leukemia
|
|
US9394567B2
(en)
|
2008-11-07 |
2016-07-19 |
Adaptive Biotechnologies Corporation |
Detection and quantification of sample contamination in immune repertoire analysis
|
|
EP2364368B1
(en)
|
2008-11-07 |
2014-01-15 |
Sequenta, Inc. |
Methods of monitoring conditions by sequence analysis
|
|
US9528160B2
(en)
|
2008-11-07 |
2016-12-27 |
Adaptive Biotechnolgies Corp. |
Rare clonotypes and uses thereof
|
|
ES2568509T3
(es)
|
2009-01-15 |
2016-04-29 |
Adaptive Biotechnologies Corporation |
Perfilado de la inmunidad adaptativa y métodos para la generación de anticuerpos monoclonales
|
|
US9085798B2
(en)
|
2009-04-30 |
2015-07-21 |
Prognosys Biosciences, Inc. |
Nucleic acid constructs and methods of use
|
|
CA2765949C
(en)
|
2009-06-25 |
2016-03-29 |
Fred Hutchinson Cancer Research Center |
Method of measuring adaptive immunity
|
|
US9315857B2
(en)
|
2009-12-15 |
2016-04-19 |
Cellular Research, Inc. |
Digital counting of individual molecules by stochastic attachment of diverse label-tags
|
|
US8835358B2
(en)
|
2009-12-15 |
2014-09-16 |
Cellular Research, Inc. |
Digital counting of individual molecules by stochastic attachment of diverse labels
|
|
US20190300945A1
(en)
|
2010-04-05 |
2019-10-03 |
Prognosys Biosciences, Inc. |
Spatially Encoded Biological Assays
|
|
US10787701B2
(en)
|
2010-04-05 |
2020-09-29 |
Prognosys Biosciences, Inc. |
Spatially encoded biological assays
|
|
KR101866401B1
(ko)
|
2010-04-05 |
2018-06-11 |
프로그노시스 바이오사이언스, 인코포레이티드 |
공간적으로 엔코딩된 생물학적 검정
|
|
EP2619327B1
(en)
*
|
2010-09-21 |
2014-10-22 |
Population Genetics Technologies LTD. |
Increasing confidence of allele calls with molecular counting
|
|
DK2630263T4
(da)
*
|
2010-10-22 |
2022-02-14 |
Cold Spring Harbor Laboratory |
Varital tælling af nucleinsyrer for at opnå information om antal genomiske kopier
|
|
US9260753B2
(en)
|
2011-03-24 |
2016-02-16 |
President And Fellows Of Harvard College |
Single cell nucleic acid detection and analysis
|
|
GB201106254D0
(en)
|
2011-04-13 |
2011-05-25 |
Frisen Jonas |
Method and product
|
|
EP3246416B1
(en)
|
2011-04-15 |
2024-06-05 |
The Johns Hopkins University |
Safe sequencing system
|
|
JP2014512826A
(ja)
|
2011-04-25 |
2014-05-29 |
バイオ−ラド ラボラトリーズ インコーポレイテッド |
核酸分析のための方法および組成物
|
|
US10385475B2
(en)
|
2011-09-12 |
2019-08-20 |
Adaptive Biotechnologies Corp. |
Random array sequencing of low-complexity libraries
|
|
EP2769007B1
(en)
|
2011-10-19 |
2016-12-07 |
Nugen Technologies, Inc. |
Compositions and methods for directional nucleic acid amplification and sequencing
|
|
HK1201565A1
(en)
|
2011-10-21 |
2015-09-04 |
Adaptive Biotechnologies Corporation |
Quantification of adaptive immune cell genomes in a complex mixture of cells
|
|
EP3388535B1
(en)
|
2011-12-09 |
2021-03-24 |
Adaptive Biotechnologies Corporation |
Diagnosis of lymphoid malignancies and minimal residual disease detection
|
|
US9499865B2
(en)
|
2011-12-13 |
2016-11-22 |
Adaptive Biotechnologies Corp. |
Detection and measurement of tissue-infiltrating lymphocytes
|
|
CN105861487B
(zh)
|
2012-01-26 |
2020-05-05 |
纽亘技术公司 |
用于靶向核酸序列富集和高效文库产生的组合物和方法
|
|
SMT202100154T1
(it)
|
2012-02-17 |
2021-05-07 |
Hutchinson Fred Cancer Res |
Composizioni e metodi per identificare precisamente mutazioni
|
|
WO2013130512A2
(en)
|
2012-02-27 |
2013-09-06 |
The University Of North Carolina At Chapel Hill |
Methods and uses for molecular tags
|
|
EP3321378B1
(en)
|
2012-02-27 |
2021-11-10 |
Becton, Dickinson and Company |
Compositions for molecular counting
|
|
EP3287531B1
(en)
|
2012-02-28 |
2019-06-19 |
Agilent Technologies, Inc. |
Method for attaching a counter sequence to a nucleic acid sample
|
|
US10077478B2
(en)
|
2012-03-05 |
2018-09-18 |
Adaptive Biotechnologies Corp. |
Determining paired immune receptor chains from frequency matched subunits
|
|
US9862995B2
(en)
|
2012-03-13 |
2018-01-09 |
Abhijit Ajit Patel |
Measurement of nucleic acid variants using highly-multiplexed error-suppressed deep sequencing
|
|
WO2013142389A1
(en)
|
2012-03-20 |
2013-09-26 |
University Of Washington Through Its Center For Commercialization |
Methods of lowering the error rate of massively parallel dna sequencing using duplex consensus sequencing
|
|
PT2831276T
(pt)
|
2012-05-08 |
2016-07-26 |
Adaptive Biotechnologies Corp |
Composições e método para medição e calibração do viés de amplificação em reações pcr multiplex
|
|
CA2877094A1
(en)
|
2012-06-18 |
2013-12-27 |
Nugen Technologies, Inc. |
Compositions and methods for negative selection of non-desired nucleic acid sequences
|
|
US20150011396A1
(en)
|
2012-07-09 |
2015-01-08 |
Benjamin G. Schroeder |
Methods for creating directional bisulfite-converted nucleic acid libraries for next generation sequencing
|
|
CN114891871A
(zh)
|
2012-08-14 |
2022-08-12 |
10X基因组学有限公司 |
微胶囊组合物及方法
|
|
US9701998B2
(en)
|
2012-12-14 |
2017-07-11 |
10X Genomics, Inc. |
Methods and systems for processing polynucleotides
|
|
US10323279B2
(en)
|
2012-08-14 |
2019-06-18 |
10X Genomics, Inc. |
Methods and systems for processing polynucleotides
|
|
US10221442B2
(en)
|
2012-08-14 |
2019-03-05 |
10X Genomics, Inc. |
Compositions and methods for sample processing
|
|
US10584381B2
(en)
|
2012-08-14 |
2020-03-10 |
10X Genomics, Inc. |
Methods and systems for processing polynucleotides
|
|
US11591637B2
(en)
|
2012-08-14 |
2023-02-28 |
10X Genomics, Inc. |
Compositions and methods for sample processing
|
|
US9951386B2
(en)
|
2014-06-26 |
2018-04-24 |
10X Genomics, Inc. |
Methods and systems for processing polynucleotides
|
|
US10752949B2
(en)
|
2012-08-14 |
2020-08-25 |
10X Genomics, Inc. |
Methods and systems for processing polynucleotides
|
|
US10273541B2
(en)
|
2012-08-14 |
2019-04-30 |
10X Genomics, Inc. |
Methods and systems for processing polynucleotides
|
|
US11913065B2
(en)
|
2012-09-04 |
2024-02-27 |
Guardent Health, Inc. |
Systems and methods to detect rare mutations and copy number variation
|
|
US10876152B2
(en)
|
2012-09-04 |
2020-12-29 |
Guardant Health, Inc. |
Systems and methods to detect rare mutations and copy number variation
|
|
PL2893040T3
(pl)
|
2012-09-04 |
2019-05-31 |
Guardant Health Inc |
Sposoby wykrywania rzadkich mutacji i wariantu liczby kopii
|
|
US20160040229A1
(en)
|
2013-08-16 |
2016-02-11 |
Guardant Health, Inc. |
Systems and methods to detect rare mutations and copy number variation
|
|
EP2904111B1
(en)
|
2012-10-01 |
2017-12-06 |
Adaptive Biotechnologies Corporation |
Immunocompetence assessment by adaptive immune receptor diversity and clonality characterization
|
|
EP3901280B1
(en)
|
2012-10-17 |
2025-03-12 |
10x Genomics Sweden AB |
Methods and product for optimising localised or spatial detection of gene expression in a tissue sample
|
|
WO2015160439A2
(en)
|
2014-04-17 |
2015-10-22 |
Adaptive Biotechnologies Corporation |
Quantification of adaptive immune cell genomes in a complex mixture of cells
|
|
WO2014070462A1
(en)
|
2012-10-29 |
2014-05-08 |
The Johns Hopkins University |
Papanicolaou test for ovarian and endometrial cancers
|
|
EP2914745B1
(en)
|
2012-11-05 |
2017-09-06 |
Rubicon Genomics, Inc. |
Barcoding nucleic acids
|
|
US10533221B2
(en)
|
2012-12-14 |
2020-01-14 |
10X Genomics, Inc. |
Methods and systems for processing polynucleotides
|
|
EP3567116A1
(en)
|
2012-12-14 |
2019-11-13 |
10X Genomics, Inc. |
Methods and systems for processing polynucleotides
|
|
EP2943590A4
(en)
|
2013-01-13 |
2017-02-15 |
Unitaq Bio |
Methods and compositions for pcr using blocked and universal primers
|
|
KR20230003659A
(ko)
|
2013-02-08 |
2023-01-06 |
10엑스 제노믹스, 인크. |
폴리뉴클레오티드 바코드 생성
|
|
EP2774998A1
(en)
|
2013-03-08 |
2014-09-10 |
Roche Diagniostics GmbH |
Improved sequence tags
|
|
WO2014144495A1
(en)
|
2013-03-15 |
2014-09-18 |
Abvitro, Inc. |
Single cell bar-coding for antibody discovery
|
|
EP2971130A4
(en)
|
2013-03-15 |
2016-10-05 |
Nugen Technologies Inc |
SEQUENTIAL SEQUENCING
|
|
ES2980689T3
(es)
|
2013-03-15 |
2024-10-02 |
Guardant Health Inc |
Métodos para la secuenciación de polinucleótidos libres de células
|
|
CN111500680B
(zh)
|
2013-06-25 |
2024-04-16 |
普罗格诺西斯生物科学公司 |
检测样品中生物靶标的空间分布的方法和系统
|
|
US9708657B2
(en)
|
2013-07-01 |
2017-07-18 |
Adaptive Biotechnologies Corp. |
Method for generating clonotype profiles using sequence tags
|
|
KR102160389B1
(ko)
|
2013-08-05 |
2020-09-28 |
트위스트 바이오사이언스 코포레이션 |
드 노보 합성된 유전자 라이브러리
|
|
CN105705659B
(zh)
|
2013-08-28 |
2019-11-29 |
贝克顿迪金森公司 |
大规模平行单细胞分析
|
|
US10395758B2
(en)
|
2013-08-30 |
2019-08-27 |
10X Genomics, Inc. |
Sequencing methods
|
|
CN105745528A
(zh)
|
2013-10-07 |
2016-07-06 |
赛卢拉研究公司 |
用于以数字方式对阵列上的特征进行计数的方法和系统
|
|
EP3066114B1
(en)
|
2013-11-07 |
2019-11-13 |
Agilent Technologies, Inc. |
Plurality of transposase adapters for dna manipulations
|
|
JP6525473B2
(ja)
*
|
2013-11-13 |
2019-06-05 |
ニューゲン テクノロジーズ， インコーポレイテッド |
複製物配列決定リードを同定するための組成物および方法
|
|
ES2693217T3
(es)
|
2013-12-02 |
2018-12-10 |
Personal Genome Diagnostics Inc. |
Método para evaluar variantes minoritarias en una muestra
|
|
US9824068B2
(en)
|
2013-12-16 |
2017-11-21 |
10X Genomics, Inc. |
Methods and apparatus for sorting data
|
|
CN111534580B
(zh)
|
2013-12-28 |
2024-06-04 |
夸登特健康公司 |
用于检测遗传变异的方法和系统
|
|
AU2015209079B2
(en)
|
2014-01-27 |
2021-07-15 |
Archerdx, Llc |
Methods of preparing nucleic acids for sequencing
|
|
CN104834833B
(zh)
*
|
2014-02-12 |
2017-12-05 |
深圳华大基因科技有限公司 |
单核苷酸多态性的检测方法及装置
|
|
WO2015131107A1
(en)
|
2014-02-28 |
2015-09-03 |
Nugen Technologies, Inc. |
Reduced representation bisulfite sequencing with diversity adaptors
|
|
CA2941612A1
(en)
|
2014-03-05 |
2015-09-11 |
Adaptive Biotechnologies Corporation |
Methods using randomer-containing synthetic molecules
|
|
US10066265B2
(en)
|
2014-04-01 |
2018-09-04 |
Adaptive Biotechnologies Corp. |
Determining antigen-specific t-cells
|
|
US9694361B2
(en)
|
2014-04-10 |
2017-07-04 |
10X Genomics, Inc. |
Fluidic devices, systems, and methods for encapsulating and partitioning reagents, and applications of same
|
|
CN106796166A
(zh)
|
2014-06-12 |
2017-05-31 |
瓦弗根公司 |
用聚合物捕获膜进行的单细胞捕获
|
|
US9757707B2
(en)
|
2014-06-12 |
2017-09-12 |
Takara Bio Usa, Inc. |
Single cell capture with capture chips
|
|
EP4235677A3
(en)
|
2014-06-26 |
2023-11-22 |
10X Genomics, Inc. |
Processes and systems for nucleic acid sequence assembly
|
|
EP4574974A3
(en)
|
2014-06-26 |
2025-10-08 |
10x Genomics, Inc. |
Methods of analyzing nucleic acids from individual cells or cell populations
|
|
US12312640B2
(en)
|
2014-06-26 |
2025-05-27 |
10X Genomics, Inc. |
Analysis of nucleic acid sequences
|
|
KR20170026383A
(ko)
|
2014-06-26 |
2017-03-08 |
10엑스 제노믹스, 인크. |
핵산 서열의 분석
|
|
WO2016002875A1
(ja)
*
|
2014-07-02 |
2016-01-07 |
株式会社Ｄｎａチップ研究所 |
核酸分子数計測法
|
|
EP3177740B1
(en)
|
2014-08-06 |
2021-01-13 |
Nugen Technologies, Inc. |
Digital measurements from targeted sequencing
|
|
US20160053301A1
(en)
|
2014-08-22 |
2016-02-25 |
Clearfork Bioscience, Inc. |
Methods for quantitative genetic analysis of cell free dna
|
|
US10590483B2
(en)
|
2014-09-15 |
2020-03-17 |
Abvitro Llc |
High-throughput nucleotide library sequencing
|
|
JP2017532042A
(ja)
|
2014-10-29 |
2017-11-02 |
１０エックス ゲノミクス，インコーポレイテッド |
標的化核酸配列決定のための方法及び組成物
|
|
CA2966201A1
(en)
|
2014-10-29 |
2016-05-06 |
Adaptive Biotechnologies Corp. |
Highly-multiplexed simultaneous detection of nucleic acids encoding paired adaptive immune receptor heterodimers from many samples
|
|
US9975122B2
(en)
|
2014-11-05 |
2018-05-22 |
10X Genomics, Inc. |
Instrument systems for integrated sample processing
|
|
US10246701B2
(en)
|
2014-11-14 |
2019-04-02 |
Adaptive Biotechnologies Corp. |
Multiplexed digital quantitation of rearranged lymphoid receptors in a complex mixture
|
|
EP3498866B1
(en)
|
2014-11-25 |
2026-02-25 |
Adaptive Biotechnologies Corp. |
Characterization of adaptive immune response to vaccination or infection using immune repertoire sequencing
|
|
AU2016207023B2
(en)
|
2015-01-12 |
2019-12-05 |
10X Genomics, Inc. |
Processes and systems for preparing nucleic acid sequencing libraries and libraries prepared using same
|
|
CA2968417A1
(en)
|
2015-01-13 |
2016-07-21 |
10X Genomics, Inc. |
Systems and methods for visualizing structural variation and phasing information
|
|
WO2016115550A1
(en)
*
|
2015-01-16 |
2016-07-21 |
Seqwell, Inc. |
Normalized iterative barcoding and sequencing of dna collections
|
|
EP3247804B1
(en)
*
|
2015-01-23 |
2020-08-05 |
Qiagen Sciences, LLC |
High multiplex pcr with molecular barcoding
|
|
US11149305B2
(en)
*
|
2015-01-23 |
2021-10-19 |
Washington University |
Detection of rare sequence variants, methods and compositions therefor
|
|
CA2975852A1
(en)
|
2015-02-04 |
2016-08-11 |
Twist Bioscience Corporation |
Methods and devices for de novo oligonucleic acid assembly
|
|
SG11201705996PA
(en)
|
2015-02-09 |
2017-09-28 |
10X Genomics Inc |
Systems and methods for determining structural variation and phasing using variant call data
|
|
US10421993B2
(en)
|
2015-02-11 |
2019-09-24 |
Paragon Genomics, Inc. |
Methods and compositions for reducing non-specific amplification products
|
|
EP3259371B1
(en)
|
2015-02-19 |
2020-09-02 |
Becton, Dickinson and Company |
High-throughput single-cell analysis combining proteomic and genomic information
|
|
WO2016134342A1
(en)
|
2015-02-20 |
2016-08-25 |
Wafergen, Inc. |
Method for rapid accurate dispensing, visualization and analysis of single cells
|
|
AU2016222719B2
(en)
|
2015-02-24 |
2022-03-31 |
10X Genomics, Inc. |
Methods for targeted nucleic acid sequence coverage
|
|
US10557134B2
(en)
|
2015-02-24 |
2020-02-11 |
Trustees Of Boston University |
Protection of barcodes during DNA amplification using molecular hairpins
|
|
EP4286516A3
(en)
|
2015-02-24 |
2024-03-06 |
10X Genomics, Inc. |
Partition processing methods and systems
|
|
WO2016138122A1
(en)
|
2015-02-24 |
2016-09-01 |
Adaptive Biotechnologies Corp. |
Methods for diagnosing infectious disease and determining hla status using immune repertoire sequencing
|
|
WO2016138496A1
(en)
|
2015-02-27 |
2016-09-01 |
Cellular Research, Inc. |
Spatially addressable molecular barcoding
|
|
CN107406888A
(zh)
|
2015-03-30 |
2017-11-28 |
赛卢拉研究公司 |
用于组合条形编码的方法和组合物
|
|
EP3277294B1
(en)
|
2015-04-01 |
2024-05-15 |
Adaptive Biotechnologies Corp. |
Method of identifying human compatible t cell receptors specific for an antigenic target
|
|
EP4321627A3
(en)
|
2015-04-10 |
2024-04-17 |
10x Genomics Sweden AB |
Spatially distinguished, multiplex nucleic acid analysis of biological specimens
|
|
BR112017021053A2
(en)
*
|
2015-04-13 |
2018-08-14 |
Alnylam Pharmaceuticals, Inc. |
angiopoietin type 3 (angpt13) irna compositions and methods of use thereof
|
|
WO2016172377A1
(en)
|
2015-04-21 |
2016-10-27 |
Twist Bioscience Corporation |
Devices and methods for oligonucleic acid library synthesis
|
|
EP3286326B1
(en)
|
2015-04-23 |
2025-01-22 |
Becton, Dickinson and Company |
Method for whole transcriptome amplification
|
|
US10844428B2
(en)
|
2015-04-28 |
2020-11-24 |
Illumina, Inc. |
Error suppression in sequenced DNA fragments using redundant reads with unique molecular indices (UMIS)
|
|
WO2016181128A1
(en)
|
2015-05-11 |
2016-11-17 |
Genefirst Ltd |
Methods, compositions, and kits for preparing sequencing library
|
|
US11124823B2
(en)
|
2015-06-01 |
2021-09-21 |
Becton, Dickinson And Company |
Methods for RNA quantification
|
|
WO2016201142A1
(en)
|
2015-06-09 |
2016-12-15 |
Life Technologies Corporation |
Methods, systems, compositions, kits, apparatus and computer-readable media for molecular tagging
|
|
GB2539675B
(en)
|
2015-06-23 |
2017-11-22 |
Cs Genetics Ltd |
Libraries of multimeric barcoding reagents and kits thereof for labelling nucleic acids for sequencing
|
|
US11286531B2
(en)
|
2015-08-11 |
2022-03-29 |
The Johns Hopkins University |
Assaying ovarian cyst fluid
|
|
US11302416B2
(en)
|
2015-09-02 |
2022-04-12 |
Guardant Health |
Machine learning for somatic single nucleotide variant detection in cell-free tumor nucleic acid sequencing applications
|
|
US12540351B2
(en)
|
2015-09-02 |
2026-02-03 |
Guardant Health, Inc. |
Identification of somatic mutations versus germline variants for cell-free DNA variant calling applications
|
|
AU2016321204B2
(en)
|
2015-09-08 |
2022-12-01 |
Cold Spring Harbor Laboratory |
Genetic copy number determination using high throughput multiplex sequencing of smashed nucleotides
|
|
WO2017044574A1
(en)
|
2015-09-11 |
2017-03-16 |
Cellular Research, Inc. |
Methods and compositions for nucleic acid library normalization
|
|
KR20180050411A
(ko)
|
2015-09-18 |
2018-05-14 |
트위스트 바이오사이언스 코포레이션 |
올리고핵산 변이체 라이브러리 및 그의 합성
|
|
WO2017053450A1
(en)
|
2015-09-22 |
2017-03-30 |
Twist Bioscience Corporation |
Flexible substrates for nucleic acid synthesis
|
|
US10465232B1
(en)
|
2015-10-08 |
2019-11-05 |
Trace Genomics, Inc. |
Methods for quantifying efficiency of nucleic acid extraction and detection
|
|
WO2017087873A1
(en)
*
|
2015-11-18 |
2017-05-26 |
Wafergen, Inc. |
Systems and methods for pooling samples from multi-well devices
|
|
US11371094B2
(en)
|
2015-11-19 |
2022-06-28 |
10X Genomics, Inc. |
Systems and methods for nucleic acid processing using degenerate nucleotides
|
|
EP3384077A4
(en)
|
2015-12-01 |
2019-05-08 |
Twist Bioscience Corporation |
FUNCTIONALIZED SURFACES AND MANUFACTURE THEREOF
|
|
KR102723865B1
(ko)
|
2015-12-04 |
2024-10-29 |
10엑스 제노믹스, 인크. |
핵산 분석을 위한 방법 및 조성물
|
|
WO2017100441A1
(en)
|
2015-12-08 |
2017-06-15 |
Twinstrand Biosciences, Inc. |
Improved adapters, methods, and compositions for duplex sequencing
|
|
SG11201805119QA
(en)
|
2015-12-17 |
2018-07-30 |
Guardant Health Inc |
Methods to determine tumor gene copy number by analysis of cell-free dna
|
|
JP6735348B2
(ja)
|
2016-02-11 |
2020-08-05 |
１０エックス ジェノミクス， インコーポレイテッド |
全ゲノム配列データのデノボアセンブリのためのシステム、方法及び媒体
|
|
KR102326769B1
(ko)
|
2016-03-25 |
2021-11-17 |
카리우스, 인코포레이티드 |
합성 핵산 스파이크-인
|
|
AU2017246318B2
(en)
|
2016-04-07 |
2023-07-27 |
The Board Of Trustees Of The Leland Stanford Junior University |
Noninvasive diagnostics by sequencing 5-hydroxymethylated cell-free DNA
|
|
US11384382B2
(en)
|
2016-04-14 |
2022-07-12 |
Guardant Health, Inc. |
Methods of attaching adapters to sample nucleic acids
|
|
WO2017181146A1
(en)
|
2016-04-14 |
2017-10-19 |
Guardant Health, Inc. |
Methods for early detection of cancer
|
|
EP3452614B1
(en)
|
2016-05-02 |
2023-06-28 |
Becton, Dickinson and Company |
Accurate molecular barcoding
|
|
US11286518B2
(en)
|
2016-05-06 |
2022-03-29 |
Regents Of The University Of Minnesota |
Analytical standards and methods of using same
|
|
WO2017197343A2
(en)
|
2016-05-12 |
2017-11-16 |
10X Genomics, Inc. |
Microfluidic on-chip filters
|
|
WO2017197338A1
(en)
|
2016-05-13 |
2017-11-16 |
10X Genomics, Inc. |
Microfluidic systems and methods of use
|
|
US10301677B2
(en)
|
2016-05-25 |
2019-05-28 |
Cellular Research, Inc. |
Normalization of nucleic acid libraries
|
|
WO2017205691A1
(en)
|
2016-05-26 |
2017-11-30 |
Cellular Research, Inc. |
Molecular label counting adjustment methods
|
|
US10202641B2
(en)
|
2016-05-31 |
2019-02-12 |
Cellular Research, Inc. |
Error correction in amplification of samples
|
|
US10640763B2
(en)
|
2016-05-31 |
2020-05-05 |
Cellular Research, Inc. |
Molecular indexing of internal sequences
|
|
WO2017210469A2
(en)
|
2016-06-01 |
2017-12-07 |
F. Hoffman-La Roche Ag |
Immuno-pete
|
|
KR102218776B1
(ko)
*
|
2016-06-10 |
2021-02-22 |
주식회사 씨젠 |
태깅 올리고뉴클레오타이드의 제공 방법
|
|
WO2018005811A1
(en)
|
2016-06-30 |
2018-01-04 |
Grail, Inc. |
Differential tagging of rna for preparation of a cell-free dna/rna sequencing library
|
|
ES2855748T3
(es)
|
2016-07-12 |
2021-09-24 |
Hoffmann La Roche |
Enriquecimiento de diana de extensión de cebador
|
|
CN109070044B
(zh)
|
2016-07-21 |
2021-07-30 |
宝生物工程（美国)有限公司 |
使用多孔装置进行的多z平面成像和分配
|
|
WO2018038772A1
(en)
|
2016-08-22 |
2018-03-01 |
Twist Bioscience Corporation |
De novo synthesized nucleic acid libraries
|
|
KR102505122B1
(ko)
|
2016-08-25 |
2023-03-08 |
레졸루션 바이오사이언스, 인크. |
Dna 샘플 중 게놈 카피 변화의 검출을 위한 방법
|
|
US12630864B2
(en)
|
2016-09-15 |
2026-05-19 |
Laboratory Corporation Of America Holdings |
Methods of nucleic acid sample preparation
|
|
US10428325B1
(en)
|
2016-09-21 |
2019-10-01 |
Adaptive Biotechnologies Corporation |
Identification of antigen-specific B cell receptors
|
|
EP4664304A3
(en)
|
2016-09-21 |
2026-01-21 |
Atlas Data Storage, Inc. |
Nucleic acid based data storage
|
|
IL265478B2
(en)
|
2016-09-26 |
2024-10-01 |
Becton Dickinson Co |
Measurement of protein expression using reagents with barcoded oligonucleotide sequences
|
|
EP3792922A1
(en)
|
2016-09-30 |
2021-03-17 |
Guardant Health, Inc. |
Methods for multi-resolution analysis of cell-free nucleic acids
|
|
US9850523B1
(en)
|
2016-09-30 |
2017-12-26 |
Guardant Health, Inc. |
Methods for multi-resolution analysis of cell-free nucleic acids
|
|
US10190155B2
(en)
|
2016-10-14 |
2019-01-29 |
Nugen Technologies, Inc. |
Molecular tag attachment and transfer
|
|
EP3800469A1
(en)
*
|
2016-10-24 |
2021-04-07 |
Ontera Inc. |
Fractional abundance of polynucleotide sequences in a sample
|
|
CN110312825A
(zh)
*
|
2016-10-24 |
2019-10-08 |
吉内恩福赛克公司 |
隐藏核酸内存在的信息
|
|
CN109844137B
(zh)
|
2016-10-31 |
2022-04-26 |
豪夫迈·罗氏有限公司 |
用于鉴定嵌合产物的条形码化环状文库构建
|
|
CN109906274B
(zh)
|
2016-11-08 |
2023-08-25 |
贝克顿迪金森公司 |
用于细胞标记分类的方法
|
|
AU2017359048B2
(en)
|
2016-11-08 |
2022-07-21 |
Becton, Dickinson And Company |
Methods for expression profile classification
|
|
GB2573069A
(en)
|
2016-12-16 |
2019-10-23 |
Twist Bioscience Corp |
Variant libraries of the immunological synapse and synthesis thereof
|
|
US10815525B2
(en)
|
2016-12-22 |
2020-10-27 |
10X Genomics, Inc. |
Methods and systems for processing polynucleotides
|
|
US10011872B1
(en)
|
2016-12-22 |
2018-07-03 |
10X Genomics, Inc. |
Methods and systems for processing polynucleotides
|
|
US10550429B2
(en)
|
2016-12-22 |
2020-02-04 |
10X Genomics, Inc. |
Methods and systems for processing polynucleotides
|
|
GB201622222D0
(en)
|
2016-12-23 |
2017-02-08 |
Cs Genetics Ltd |
Reagents and methods for molecular barcoding of nucleic acids of single cells
|
|
GB201622219D0
(en)
|
2016-12-23 |
2017-02-08 |
Cs Genetics Ltd |
Methods and reagents for molecular barcoding
|
|
CN110382716A
(zh)
|
2017-01-10 |
2019-10-25 |
佰隆基因公司 |
用于减少引物延伸反应中产生的冗余分子条形码的方法和组合物
|
|
WO2018132610A1
(en)
|
2017-01-13 |
2018-07-19 |
Cellular Research, Inc. |
Hydrophilic coating of fluidic channels
|
|
CN116497103A
(zh)
|
2017-01-18 |
2023-07-28 |
伊鲁米那股份有限公司 |
制备测序衔接子的方法和对核酸分子进行测序的方法
|
|
US12264411B2
(en)
|
2017-01-30 |
2025-04-01 |
10X Genomics, Inc. |
Methods and systems for analysis
|
|
EP4310183B1
(en)
|
2017-01-30 |
2025-07-09 |
10X Genomics, Inc. |
Methods and systems for droplet-based single cell barcoding
|
|
US11319583B2
(en)
|
2017-02-01 |
2022-05-03 |
Becton, Dickinson And Company |
Selective amplification using blocking oligonucleotides
|
|
WO2018145041A1
(en)
|
2017-02-06 |
2018-08-09 |
10X Genomics, Inc. |
Systems and methods for nucleic acid preparation
|
|
WO2018156792A1
(en)
|
2017-02-22 |
2018-08-30 |
Twist Bioscience Corporation |
Nucleic acid based data storage
|
|
US12297491B2
(en)
|
2017-03-08 |
2025-05-13 |
Roche Sequencing Solutions, Inc. |
Primer extension target enrichment and improvements thereto including simultaneous enrichment of DNA and RNA
|
|
JP6970205B2
(ja)
|
2017-03-08 |
2021-11-24 |
エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft |
Ｄｎａおよびｒｎａの同時濃縮を含むプライマー伸長標的濃縮およびそれに対する向上
|
|
CA3056388A1
(en)
|
2017-03-15 |
2018-09-20 |
Twist Bioscience Corporation |
Variant libraries of the immunological synapse and synthesis thereof
|
|
WO2018183942A1
(en)
|
2017-03-31 |
2018-10-04 |
Grail, Inc. |
Improved library preparation and use thereof for sequencing-based error correction and/or variant identification
|
|
US12492430B2
(en)
|
2017-04-11 |
2025-12-09 |
Tecan Genomics, Inc. |
Library quantitation and qualification
|
|
AU2018254190B2
(en)
|
2017-04-17 |
2024-05-30 |
Guoliang Fu |
Methods, compositions, and kits for preparing nucleic acid libraries
|
|
WO2018213774A1
(en)
|
2017-05-19 |
2018-11-22 |
10X Genomics, Inc. |
Systems and methods for analyzing datasets
|
|
US10844372B2
(en)
|
2017-05-26 |
2020-11-24 |
10X Genomics, Inc. |
Single cell analysis of transposase accessible chromatin
|
|
CN116064732A
(zh)
|
2017-05-26 |
2023-05-05 |
10X基因组学有限公司 |
转座酶可接近性染色质的单细胞分析
|
|
JP7536450B2
(ja)
|
2017-06-05 |
2024-08-20 |
ベクトン・ディキンソン・アンド・カンパニー |
単一細胞用のサンプルインデックス付加
|
|
IL271205B2
(en)
|
2017-06-12 |
2025-02-01 |
Twist Bioscience Corp |
Methods for assembling continuous nucleic acids
|
|
WO2018231864A1
(en)
|
2017-06-12 |
2018-12-20 |
Twist Bioscience Corporation |
Methods for seamless nucleic acid assembly
|
|
US11542540B2
(en)
|
2017-06-16 |
2023-01-03 |
Life Technologies Corporation |
Control nucleic acids, and compositions, kits, and uses thereof
|
|
US11505826B2
(en)
|
2017-07-12 |
2022-11-22 |
Agilent Technologies, Inc. |
Sequencing method for genomic rearrangement detection
|
|
KR20250047324A
(ko)
|
2017-08-07 |
2025-04-03 |
더 존스 홉킨스 유니버시티 |
암을 평가하고 치료하기 위한 방법 및 재료
|
|
CN111566125A
(zh)
|
2017-09-11 |
2020-08-21 |
特韦斯特生物科学公司 |
Gpcr结合蛋白及其合成
|
|
JP2020532976A
(ja)
|
2017-09-14 |
2020-11-19 |
エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ |
環状一本鎖ｄｎａライブラリーを生成するための新規な方法
|
|
US11447818B2
(en)
|
2017-09-15 |
2022-09-20 |
Illumina, Inc. |
Universal short adapters with variable length non-random unique molecular identifiers
|
|
EP3682027B1
(en)
|
2017-09-15 |
2025-02-26 |
F. Hoffmann-La Roche AG |
Hybridization-extension-ligation strategy for generating circular single-stranded dna libraries
|
|
US10837047B2
(en)
|
2017-10-04 |
2020-11-17 |
10X Genomics, Inc. |
Compositions, methods, and systems for bead formation using improved polymers
|
|
WO2019068797A1
(en)
|
2017-10-06 |
2019-04-11 |
F. Hoffmann-La Roche Ag |
CIRCULARIZATION METHODS FOR THE PREPARATION OF SAMPLE SAMPLES OF UNIQUE MOLECULES
|
|
US11099202B2
(en)
|
2017-10-20 |
2021-08-24 |
Tecan Genomics, Inc. |
Reagent delivery system
|
|
CN111565834B
(zh)
|
2017-10-20 |
2022-08-26 |
特韦斯特生物科学公司 |
用于多核苷酸合成的加热的纳米孔
|
|
WO2019084043A1
(en)
|
2017-10-26 |
2019-05-02 |
10X Genomics, Inc. |
METHODS AND SYSTEMS FOR NUCLEIC ACID PREPARATION AND CHROMATIN ANALYSIS
|
|
CN111479631B
(zh)
|
2017-10-27 |
2022-02-22 |
10X基因组学有限公司 |
用于样品制备和分析的方法和系统
|
|
WO2019086531A1
(en)
|
2017-11-03 |
2019-05-09 |
F. Hoffmann-La Roche Ag |
Linear consensus sequencing
|
|
CN111542616A
(zh)
|
2017-11-03 |
2020-08-14 |
夸登特健康公司 |
脱氨引起的序列错误的纠正
|
|
CA3081027A1
(en)
|
2017-11-08 |
2019-05-16 |
Twinstrand Biosciences, Inc. |
Reagents and adapters for nucleic acid sequencing and methods for making such reagents and adapters
|
|
EP3625361A1
(en)
|
2017-11-15 |
2020-03-25 |
10X Genomics, Inc. |
Functionalized gel beads
|
|
WO2019099908A1
(en)
|
2017-11-17 |
2019-05-23 |
10X Genomics, Inc. |
Methods and systems for associating physical and genetic properties of biological particles
|
|
US11254980B1
(en)
|
2017-11-29 |
2022-02-22 |
Adaptive Biotechnologies Corporation |
Methods of profiling targeted polynucleotides while mitigating sequencing depth requirements
|
|
WO2019108851A1
(en)
|
2017-11-30 |
2019-06-06 |
10X Genomics, Inc. |
Systems and methods for nucleic acid preparation and analysis
|
|
CN118818037A
(zh)
|
2017-12-12 |
2024-10-22 |
10X基因组学有限公司 |
用于单细胞处理的系统和方法
|
|
CN111492068B
(zh)
|
2017-12-19 |
2025-03-21 |
贝克顿迪金森公司 |
与寡核苷酸相关联的颗粒
|
|
EP4269582A3
(en)
|
2017-12-21 |
2024-01-24 |
F. Hoffmann-La Roche AG |
Target enrichment by unidirectional dual probe primer extension
|
|
WO2019126789A1
(en)
|
2017-12-22 |
2019-06-27 |
10X Genomics, Inc. |
Systems and methods for processing nucleic acid molecules from one or more cells
|
|
WO2019136058A1
(en)
|
2018-01-02 |
2019-07-11 |
The Regents Of The University Of Michigan |
Multi-droplet capture
|
|
IL312616B2
(en)
|
2018-01-04 |
2025-08-01 |
Twist Bioscience Corp |
Dna-based digital information storage
|
|
CN111801427B
(zh)
|
2018-02-05 |
2023-12-05 |
豪夫迈·罗氏有限公司 |
用于单分子的单链环状dna模板的产生
|
|
EP3752832A1
(en)
|
2018-02-12 |
2020-12-23 |
10X Genomics, Inc. |
Methods characterizing multiple analytes from individual cells or cell populations
|
|
WO2019160994A1
(en)
|
2018-02-14 |
2019-08-22 |
Bluestar Genomics, Inc. |
Methods for the epigenetic analysis of dna, particularly cell-free dna
|
|
US11639928B2
(en)
|
2018-02-22 |
2023-05-02 |
10X Genomics, Inc. |
Methods and systems for characterizing analytes from individual cells or cell populations
|
|
WO2019169028A1
(en)
|
2018-02-28 |
2019-09-06 |
10X Genomics, Inc. |
Transcriptome sequencing through random ligation
|
|
WO2019166565A1
(en)
|
2018-03-02 |
2019-09-06 |
F. Hoffmann-La Roche Ag |
Generation of double-stranded dna templates for single molecule sequencing
|
|
GB201804641D0
(en)
|
2018-03-22 |
2018-05-09 |
Inivata Ltd |
Methods of sequencing nucleic acids and error correction of sequence reads
|
|
CA3302676A1
(en)
|
2018-04-02 |
2026-05-13 |
Grail, Inc. |
Methylation markers and targeted methylation probe panels
|
|
WO2019191900A1
(en)
|
2018-04-03 |
2019-10-10 |
Burning Rock Biotech |
Compositions and methods for preparing nucleic acid libraries
|
|
EP3775271B1
(en)
|
2018-04-06 |
2025-03-12 |
10X Genomics, Inc. |
Systems and methods for quality control in single cell processing
|
|
CA3097976A1
(en)
|
2018-05-03 |
2019-11-07 |
Becton, Dickinson And Company |
High throughput multiomics sample analysis
|
|
EP3788170B1
(en)
|
2018-05-03 |
2025-01-01 |
Becton, Dickinson and Company |
Molecular barcoding on opposite transcript ends
|
|
JP7274504B2
(ja)
|
2018-05-08 |
2023-05-16 |
エフ． ホフマン－ラ ロシュ アーゲー |
多様度指数を確立することで腫瘍バリアント多様度を評価することによるがん予後診断の方法
|
|
WO2019217758A1
(en)
|
2018-05-10 |
2019-11-14 |
10X Genomics, Inc. |
Methods and systems for molecular library generation
|
|
EP3814497A4
(en)
|
2018-05-18 |
2022-03-02 |
Twist Bioscience Corporation |
POLYNUCLEOTIDES, REAGENTS AND METHODS FOR NUCLEIC ACID HYBRIDIZATION
|
|
US11932899B2
(en)
|
2018-06-07 |
2024-03-19 |
10X Genomics, Inc. |
Methods and systems for characterizing nucleic acid molecules
|
|
WO2019238939A1
(en)
|
2018-06-15 |
2019-12-19 |
F. Hoffmann-La Roche Ag |
A system for identification of antigens recognized by t cell receptors expressed on tumor infiltrating lymphocytes
|
|
US11703427B2
(en)
|
2018-06-25 |
2023-07-18 |
10X Genomics, Inc. |
Methods and systems for cell and bead processing
|
|
AU2019300172A1
(en)
|
2018-07-12 |
2021-01-28 |
Twinstrand Biosciences, Inc. |
Methods and reagents for characterizing genomic editing, clonal expansion, and associated applications
|
|
US12188014B1
(en)
|
2018-07-25 |
2025-01-07 |
10X Genomics, Inc. |
Compositions and methods for nucleic acid processing using blocking agents
|
|
US20210292851A1
(en)
|
2018-07-27 |
2021-09-23 |
Roche Sequencing Solutions, Inc. |
Method of monitoring effectiveness of immunotherapy of cancer patients
|
|
US20200032335A1
(en)
|
2018-07-27 |
2020-01-30 |
10X Genomics, Inc. |
Systems and methods for metabolome analysis
|
|
US12163179B2
(en)
|
2018-08-03 |
2024-12-10 |
10X Gemomics, Inc. |
Methods and systems to minimize barcode exchange
|
|
WO2020041148A1
(en)
|
2018-08-20 |
2020-02-27 |
10X Genomics, Inc. |
Methods and systems for detection of protein-dna interactions using proximity ligation
|
|
US12065688B2
(en)
|
2018-08-20 |
2024-08-20 |
10X Genomics, Inc. |
Compositions and methods for cellular processing
|
|
US11519033B2
(en)
|
2018-08-28 |
2022-12-06 |
10X Genomics, Inc. |
Method for transposase-mediated spatial tagging and analyzing genomic DNA in a biological sample
|
|
US20200075123A1
(en)
|
2018-08-31 |
2020-03-05 |
Guardant Health, Inc. |
Genetic variant detection based on merged and unmerged reads
|
|
JP7152599B2
(ja)
|
2018-09-21 |
2022-10-12 |
エフ．ホフマン－ラ ロシュ アーゲー |
塩基配列決定のためのモジュール式およびコンビナトリアル核酸試料調製のためのシステムおよび方法
|
|
EP3856903A4
(en)
|
2018-09-27 |
2022-07-27 |
Grail, LLC |
METHYLATION MARKER AND TARGETED METHYLATION PROBE PANEL
|
|
EP3861134B1
(en)
|
2018-10-01 |
2024-09-04 |
Becton, Dickinson and Company |
Determining 5' transcript sequences
|
|
EP3877520B1
(en)
|
2018-11-08 |
2025-03-19 |
Becton, Dickson And Company |
Whole transcriptome analysis of single cells using random priming
|
|
EP4700161A3
(en)
|
2018-11-21 |
2026-03-11 |
Karius, Inc. |
Direct-to-library methods, systems, and compositions
|
|
US12529094B2
(en)
|
2018-12-10 |
2026-01-20 |
10X Genomics, Inc. |
Imaging system hardware
|
|
EP3894585A2
(en)
|
2018-12-10 |
2021-10-20 |
10X Genomics, Inc. |
Generating capture probes for spatial analysis
|
|
US11459607B1
(en)
|
2018-12-10 |
2022-10-04 |
10X Genomics, Inc. |
Systems and methods for processing-nucleic acid molecules from a single cell using sequential co-partitioning and composite barcodes
|
|
EP3894552B1
(en)
|
2018-12-13 |
2026-01-28 |
Becton, Dickinson and Company |
Selective extension in single cell whole transcriptome analysis
|
|
EP3902816A4
(en)
|
2018-12-26 |
2022-09-14 |
Twist Bioscience Corporation |
HIGH-PRECISION DE NOVO POLYNUCLEOTIDE SYNTHESIS
|
|
US20220081714A1
(en)
|
2019-01-04 |
2022-03-17 |
Northwestern University |
Storing temporal data into dna
|
|
CA3125458A1
(en)
*
|
2019-01-04 |
2020-07-09 |
William Marsh Rice University |
Quantitative amplicon sequencing for multiplexed copy number variation detection and allele ratio quantitation
|
|
US11926867B2
(en)
|
2019-01-06 |
2024-03-12 |
10X Genomics, Inc. |
Generating capture probes for spatial analysis
|
|
US11649485B2
(en)
|
2019-01-06 |
2023-05-16 |
10X Genomics, Inc. |
Generating capture probes for spatial analysis
|
|
US12169198B2
(en)
|
2019-01-08 |
2024-12-17 |
10X Genomics, Inc. |
Systems and methods for sample analysis
|
|
US11845983B1
(en)
|
2019-01-09 |
2023-12-19 |
10X Genomics, Inc. |
Methods and systems for multiplexing of droplet based assays
|
|
WO2020150356A1
(en)
|
2019-01-16 |
2020-07-23 |
Becton, Dickinson And Company |
Polymerase chain reaction normalization through primer titration
|
|
EP3914728B1
(en)
|
2019-01-23 |
2023-04-05 |
Becton, Dickinson and Company |
Oligonucleotides associated with antibodies
|
|
EP4567131A3
(en)
|
2019-01-31 |
2025-09-03 |
Guardant Health, Inc. |
Compositions and methods for isolating cell-free dna
|
|
WO2020167862A1
(en)
|
2019-02-12 |
2020-08-20 |
10X Genomics, Inc. |
Systems and methods for transfer of reagents between droplets
|
|
WO2020167866A1
(en)
|
2019-02-12 |
2020-08-20 |
10X Genomics, Inc. |
Systems and methods for transposon loading
|
|
WO2020168013A1
(en)
|
2019-02-12 |
2020-08-20 |
10X Genomics, Inc. |
Methods for processing nucleic acid molecules
|
|
US12305239B2
(en)
|
2019-02-12 |
2025-05-20 |
10X Genomics, Inc. |
Analysis of nucleic acid sequences
|
|
US12275993B2
(en)
|
2019-02-12 |
2025-04-15 |
10X Genomics, Inc. |
Analysis of nucleic acid sequences
|
|
US11851683B1
(en)
|
2019-02-12 |
2023-12-26 |
10X Genomics, Inc. |
Methods and systems for selective analysis of cellular samples
|
|
US11467153B2
(en)
|
2019-02-12 |
2022-10-11 |
10X Genomics, Inc. |
Methods for processing nucleic acid molecules
|
|
CN113454234B
(zh)
|
2019-02-14 |
2025-03-18 |
贝克顿迪金森公司 |
杂合体靶向和全转录物组扩增
|
|
US11655499B1
(en)
|
2019-02-25 |
2023-05-23 |
10X Genomics, Inc. |
Detection of sequence elements in nucleic acid molecules
|
|
KR20210144698A
(ko)
|
2019-02-26 |
2021-11-30 |
트위스트 바이오사이언스 코포레이션 |
항체 최적화를 위한 변이 핵산 라이브러리
|
|
CA3131689A1
(en)
|
2019-02-26 |
2020-09-03 |
Twist Bioscience Corporation |
Variant nucleic acid libraries for glp1 receptor
|
|
SG11202111242PA
(en)
|
2019-03-11 |
2021-11-29 |
10X Genomics Inc |
Systems and methods for processing optically tagged beads
|
|
EP3947722A1
(en)
|
2019-03-27 |
2022-02-09 |
10X Genomics, Inc. |
Systems and methods for processing rna from cells
|
|
US11965208B2
(en)
|
2019-04-19 |
2024-04-23 |
Becton, Dickinson And Company |
Methods of associating phenotypical data and single cell sequencing data
|
|
EP3976820A1
(en)
|
2019-05-30 |
2022-04-06 |
10X Genomics, Inc. |
Methods of detecting spatial heterogeneity of a biological sample
|
|
EP3987019A4
(en)
|
2019-06-21 |
2023-04-19 |
Twist Bioscience Corporation |
Barcode-based nucleic acid sequence assembly
|
|
WO2021016239A1
(en)
|
2019-07-22 |
2021-01-28 |
Becton, Dickinson And Company |
Single cell chromatin immunoprecipitation sequencing assay
|
|
EP4017977A1
(en)
|
2019-08-19 |
2022-06-29 |
F. Hoffmann-La Roche AG |
Single tube preparation of dna and rna for sequencing
|
|
US12235262B1
(en)
|
2019-09-09 |
2025-02-25 |
10X Genomics, Inc. |
Methods and systems for single cell protein analysis
|
|
EP4031679A1
(en)
|
2019-09-20 |
2022-07-27 |
F. Hoffmann-La Roche AG |
Immune repertoire profiling by primer extension target enrichment
|
|
EP3795685A1
(en)
|
2019-09-20 |
2021-03-24 |
Sophia Genetics S.A. |
Methods for dna library generation to facilitate the detection and reporting of low frequency variants
|
|
CN115023440B
(zh)
|
2019-09-23 |
2025-09-12 |
特韦斯特生物科学公司 |
结合CD3ε的抗体
|
|
US12091777B2
(en)
|
2019-09-23 |
2024-09-17 |
Twist Bioscience Corporation |
Variant nucleic acid libraries for CRTH2
|
|
AU2020378435B2
(en)
|
2019-11-06 |
2026-07-30 |
The Board Of Trustees Of The Leland Stanford Junior University |
Methods and systems for analyzing nucleic acid molecules
|
|
EP4025711A2
(en)
|
2019-11-08 |
2022-07-13 |
10X Genomics, Inc. |
Enhancing specificity of analyte binding
|
|
EP4055160B1
(en)
|
2019-11-08 |
2024-04-10 |
Becton Dickinson and Company |
Using random priming to obtain full-length v(d)j information for immune repertoire sequencing
|
|
AU2020400030B2
(en)
|
2019-12-09 |
2026-05-21 |
Twist Bioscience Corporation |
Variant nucleic acid libraries for adenosine receptors
|
|
EP4081656A1
(en)
|
2019-12-23 |
2022-11-02 |
10X Genomics, Inc. |
Compositions and methods for using fixed biological samples in partition-based assays
|
|
CN121022991A
(zh)
|
2019-12-23 |
2025-11-28 |
10X基因组学有限公司 |
使用rna模板化连接进行空间分析的方法
|
|
EP4752521A3
(en)
|
2019-12-23 |
2026-08-12 |
10X Genomics, Inc. |
Reversible fixing reagents and methods of use thereof
|
|
CN115279919A
(zh)
|
2020-01-13 |
2022-11-01 |
贝克顿迪金森公司 |
使用含有du的寡核苷酸的细胞捕获
|
|
CN115244184A
(zh)
|
2020-01-13 |
2022-10-25 |
贝克顿迪金森公司 |
用于定量蛋白和rna的方法和组合物
|
|
US12365942B2
(en)
|
2020-01-13 |
2025-07-22 |
10X Genomics, Inc. |
Methods of decreasing background on a spatial array
|
|
US12405264B2
(en)
|
2020-01-17 |
2025-09-02 |
10X Genomics, Inc. |
Electrophoretic system and method for analyte capture
|
|
EP3851542A1
(en)
|
2020-01-20 |
2021-07-21 |
Tecan Genomics, Inc. |
Depletion of abundant uninformative sequences
|
|
US11702693B2
(en)
|
2020-01-21 |
2023-07-18 |
10X Genomics, Inc. |
Methods for printing cells and generating arrays of barcoded cells
|
|
US11732299B2
(en)
|
2020-01-21 |
2023-08-22 |
10X Genomics, Inc. |
Spatial assays with perturbed cells
|
|
US20210230681A1
(en)
|
2020-01-24 |
2021-07-29 |
10X Genomics, Inc. |
Methods for spatial analysis using proximity ligation
|
|
WO2021155057A1
(en)
|
2020-01-29 |
2021-08-05 |
Becton, Dickinson And Company |
Barcoded wells for spatial mapping of single cells through sequencing
|
|
US12076701B2
(en)
|
2020-01-31 |
2024-09-03 |
10X Genomics, Inc. |
Capturing oligonucleotides in spatial transcriptomics
|
|
US11898205B2
(en)
|
2020-02-03 |
2024-02-13 |
10X Genomics, Inc. |
Increasing capture efficiency of spatial assays
|
|
US12110541B2
(en)
|
2020-02-03 |
2024-10-08 |
10X Genomics, Inc. |
Methods for preparing high-resolution spatial arrays
|
|
CN113275053A
(zh)
|
2020-02-03 |
2021-08-20 |
帝肯基因组学公司 |
试剂存储系统
|
|
US11732300B2
(en)
|
2020-02-05 |
2023-08-22 |
10X Genomics, Inc. |
Increasing efficiency of spatial analysis in a biological sample
|
|
US12129516B2
(en)
|
2020-02-07 |
2024-10-29 |
10X Genomics, Inc. |
Quantitative and automated permeabilization performance evaluation for spatial transcriptomics
|
|
US12449419B1
(en)
|
2020-02-12 |
2025-10-21 |
10X Genomics, Inc. |
Methods for detecting binding of peptide-MHC monomers to T cells
|
|
EP4104179B1
(en)
|
2020-02-13 |
2026-01-28 |
10X Genomics, Inc. |
Systems and methods for joint interactive visualization of gene expression and dna chromatin accessibility
|
|
WO2021163546A1
(en)
|
2020-02-14 |
2021-08-19 |
The Johns Hopkins University |
Methods and materials for assessing nucleic acids
|
|
US12281357B1
(en)
|
2020-02-14 |
2025-04-22 |
10X Genomics, Inc. |
In situ spatial barcoding
|
|
US11211144B2
(en)
|
2020-02-18 |
2021-12-28 |
Tempus Labs, Inc. |
Methods and systems for refining copy number variation in a liquid biopsy assay
|
|
US11475981B2
(en)
|
2020-02-18 |
2022-10-18 |
Tempus Labs, Inc. |
Methods and systems for dynamic variant thresholding in a liquid biopsy assay
|
|
US11211147B2
(en)
|
2020-02-18 |
2021-12-28 |
Tempus Labs, Inc. |
Estimation of circulating tumor fraction using off-target reads of targeted-panel sequencing
|
|
CN116157533A
(zh)
|
2020-02-21 |
2023-05-23 |
10X基因组学有限公司 |
使用杂交方法捕获遗传靶标
|
|
US11891654B2
(en)
|
2020-02-24 |
2024-02-06 |
10X Genomics, Inc. |
Methods of making gene expression libraries
|
|
ES3040741T3
(en)
|
2020-02-24 |
2025-11-04 |
Univ Leland Stanford Junior |
Methods of analyzing cell free nucleic acids and applications thereof
|
|
US12153043B2
(en)
|
2020-02-25 |
2024-11-26 |
Becton, Dickinson And Company |
Bi-specific probes to enable the use of single-cell samples as single color compensation control
|
|
JP7490071B2
(ja)
|
2020-03-11 |
2024-05-24 |
エフ． ホフマン－ラ ロシュ アーゲー |
シーケンシングのための新規核酸鋳型構造
|
|
JP2023519979A
(ja)
|
2020-04-03 |
2023-05-15 |
エフ． ホフマン－ラ ロシュ アーゲー |
ゲノム内の構造再編成の検出方法
|
|
EP4139485B1
(en)
|
2020-04-22 |
2023-09-06 |
10X Genomics, Inc. |
Methods for spatial analysis using targeted rna depletion
|
|
US11851700B1
(en)
|
2020-05-13 |
2023-12-26 |
10X Genomics, Inc. |
Methods, kits, and compositions for processing extracellular molecules
|
|
WO2021231779A1
(en)
|
2020-05-14 |
2021-11-18 |
Becton, Dickinson And Company |
Primers for immune repertoire profiling
|
|
US10941453B1
(en)
|
2020-05-20 |
2021-03-09 |
Paragon Genomics, Inc. |
High throughput detection of pathogen RNA in clinical specimens
|
|
AU2021275906A1
(en)
|
2020-05-22 |
2022-12-22 |
10X Genomics, Inc. |
Spatial analysis to detect sequence variants
|
|
EP4153775B1
(en)
|
2020-05-22 |
2024-07-24 |
10X Genomics, Inc. |
Simultaneous spatio-temporal measurement of gene expression and cellular activity
|
|
WO2021242834A1
(en)
|
2020-05-26 |
2021-12-02 |
10X Genomics, Inc. |
Method for resetting an array
|
|
CN115803445A
(zh)
|
2020-06-02 |
2023-03-14 |
贝克顿迪金森公司 |
用于5撇基因表达测定的寡核苷酸和珠
|
|
US12031177B1
(en)
|
2020-06-04 |
2024-07-09 |
10X Genomics, Inc. |
Methods of enhancing spatial resolution of transcripts
|
|
US20230287508A1
(en)
|
2020-06-08 |
2023-09-14 |
Roche Sequencing Solutions, Inc. |
Methods and compositions for detecting structural rearrangements in a genome
|
|
EP4421186B1
(en)
|
2020-06-08 |
2025-08-13 |
10X Genomics, Inc. |
Methods of determining a surgical margin and methods of use thereof
|
|
EP4446430A3
(en)
|
2020-06-10 |
2024-12-18 |
10X Genomics, Inc. |
Methods for determining a location of an analyte in a biological sample
|
|
EP4450639B1
(en)
|
2020-06-25 |
2025-10-15 |
10X Genomics, Inc. |
Spatial analysis of dna methylation
|
|
US11761038B1
(en)
|
2020-07-06 |
2023-09-19 |
10X Genomics, Inc. |
Methods for identifying a location of an RNA in a biological sample
|
|
US12209280B1
(en)
|
2020-07-06 |
2025-01-28 |
10X Genomics, Inc. |
Methods of identifying abundance and location of an analyte in a biological sample using second strand synthesis
|
|
US11981960B1
(en)
|
2020-07-06 |
2024-05-14 |
10X Genomics, Inc. |
Spatial analysis utilizing degradable hydrogels
|
|
CN115956128B
(zh)
|
2020-07-08 |
2026-03-27 |
豪夫迈·罗氏有限公司 |
在下一代测序文库的靶捕获过程中使用毒性引物对非靶文库分子进行靶向消耗
|
|
US20230340578A1
(en)
|
2020-07-08 |
2023-10-26 |
Roche Sequencing Solutions, Inc. |
Spatial analysis of multiple targets in tissue samples
|
|
US11932901B2
(en)
|
2020-07-13 |
2024-03-19 |
Becton, Dickinson And Company |
Target enrichment using nucleic acid probes for scRNAseq
|
|
WO2022026909A1
(en)
|
2020-07-31 |
2022-02-03 |
Becton, Dickinson And Company |
Single cell assay for transposase-accessible chromatin
|
|
US11981958B1
(en)
|
2020-08-20 |
2024-05-14 |
10X Genomics, Inc. |
Methods for spatial analysis using DNA capture
|
|
US11926822B1
(en)
|
2020-09-23 |
2024-03-12 |
10X Genomics, Inc. |
Three-dimensional spatial analysis
|
|
US12655450B1
(en)
|
2020-10-27 |
2026-06-16 |
10X Genomics, Inc. |
Methods, systems, and kits for detection of nucleic acid molecules
|
|
US12480158B1
(en)
|
2020-11-05 |
2025-11-25 |
10X Genomics, Inc. |
Methods and systems for processing polynucleotides
|
|
US12084715B1
(en)
|
2020-11-05 |
2024-09-10 |
10X Genomics, Inc. |
Methods and systems for reducing artifactual antisense products
|
|
US11827935B1
(en)
|
2020-11-19 |
2023-11-28 |
10X Genomics, Inc. |
Methods for spatial analysis using rolling circle amplification and detection probes
|
|
WO2022109343A1
(en)
|
2020-11-20 |
2022-05-27 |
Becton, Dickinson And Company |
Profiling of highly expressed and lowly expressed proteins
|
|
US12378596B2
(en)
|
2020-12-03 |
2025-08-05 |
Roche Sequencing Solutions, Inc. |
Whole transcriptome analysis in single cells
|
|
CN116685850A
(zh)
|
2020-12-15 |
2023-09-01 |
贝克顿迪金森公司 |
单细胞分泌组分析
|
|
WO2022140028A1
(en)
|
2020-12-21 |
2022-06-30 |
10X Genomics, Inc. |
Methods, compositions, and systems for capturing probes and/or barcodes
|
|
CN112466405B
(zh)
*
|
2020-12-23 |
2021-06-22 |
阅尔基因技术（苏州）有限公司 |
一种制备测序用分子标签库的方法
|
|
US12037640B2
(en)
|
2021-01-08 |
2024-07-16 |
Agilent Technologies, Inc. |
Sequencing an insert and an identifier without denaturation
|
|
US12398262B1
(en)
|
2021-01-22 |
2025-08-26 |
10X Genomics, Inc. |
Triblock copolymer-based cell stabilization and fixation system and methods of use thereof
|
|
WO2022171606A2
(en)
|
2021-02-09 |
2022-08-18 |
F. Hoffmann-La Roche Ag |
Methods for base-level detection of methylation in nucleic acids
|
|
WO2022174898A1
(en)
|
2021-02-18 |
2022-08-25 |
F. Hoffmann-La Roche Ag |
Structure to prevent threading of nucleic acid templates through a nanopore during sequencing
|
|
AU2022227563A1
(en)
|
2021-02-23 |
2023-08-24 |
10X Genomics, Inc. |
Probe-based analysis of nucleic acids and proteins
|
|
US11280028B1
(en)
|
2021-02-24 |
2022-03-22 |
Agency For Science, Technology And Research (A*Star) |
Unbiased and simultaneous amplification method for preparing a double-stranded DNA library from a sample of more than one type of nucleic acid
|
|
CN117062902A
(zh)
|
2021-03-03 |
2023-11-14 |
豪夫迈·罗氏有限公司 |
用于从生物学样品中电泳提取核酸的装置和方法
|
|
WO2022194764A1
(en)
|
2021-03-15 |
2022-09-22 |
F. Hoffmann-La Roche Ag |
Targeted next-generation sequencing via anchored primer extension
|
|
EP4314337A1
(en)
|
2021-04-01 |
2024-02-07 |
F. Hoffmann-La Roche AG |
Immune cell counting of sars-cov-2 patients based on immune repertoire sequencing
|
|
EP4305196B1
(en)
|
2021-04-14 |
2025-04-02 |
10X Genomics, Inc. |
Methods of measuring mislocalization of an analyte
|
|
US11783912B2
(en)
|
2021-05-05 |
2023-10-10 |
The Board Of Trustees Of The Leland Stanford Junior University |
Methods and systems for analyzing nucleic acid molecules
|
|
EP4320271B1
(en)
|
2021-05-06 |
2025-03-19 |
10X Genomics, Inc. |
Methods for increasing resolution of spatial analysis
|
|
WO2022248237A1
(en)
|
2021-05-24 |
2022-12-01 |
F. Hoffmann-La Roche Ag |
Enhancer oligonucleotides for nucleic acid hybridization
|
|
ES3030033T3
(en)
|
2021-06-03 |
2025-06-26 |
10X Genomics Inc |
Methods, compositions, kits, and systems for enhancing analyte capture for spatial analysis
|
|
GB202108427D0
(en)
|
2021-06-14 |
2021-07-28 |
Fu Guoliang |
Methods, compositions, and kits for preparing sequencing library
|
|
WO2022263846A1
(en)
|
2021-06-18 |
2022-12-22 |
Cs Genetics Limited |
Reagents and methods for molecular barcoding
|
|
WO2023034489A1
(en)
|
2021-09-01 |
2023-03-09 |
10X Genomics, Inc. |
Methods, compositions, and kits for blocking a capture probe on a spatial array
|
|
CN118266034A
(zh)
|
2021-10-04 |
2024-06-28 |
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|
|
EP4419707A1
(en)
|
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|
|
EP4305195A2
(en)
|
2021-12-01 |
2024-01-17 |
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|
|
CN118355129A
(zh)
|
2021-12-07 |
2024-07-16 |
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|
|
CN114561453A
(zh)
*
|
2022-01-28 |
2022-05-31 |
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|
|
US11680293B1
(en)
|
2022-04-21 |
2023-06-20 |
Paragon Genomics, Inc. |
Methods and compositions for amplifying DNA and generating DNA sequencing results from target-enriched DNA molecules
|
|
US12091715B2
(en)
|
2022-04-21 |
2024-09-17 |
Paragon Genomics, Inc. |
Methods and compositions for reducing base errors of massive parallel sequencing using triseq sequencing
|
|
EP4540408A1
(en)
|
2022-06-14 |
2025-04-23 |
F. Hoffmann-La Roche AG |
Detection of epigenetic cytosine modification
|
|
WO2024013241A1
(en)
|
2022-07-14 |
2024-01-18 |
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Variant allele enrichment by unidirectional dual probe primer extension
|
|
JP2025527591A
(ja)
|
2022-08-18 |
2025-08-22 |
エフ． ホフマン－ラ ロシュ アーゲー |
エピジェネティック修飾の検出
|
|
WO2024046992A1
(en)
|
2022-09-02 |
2024-03-07 |
F. Hoffmann-La Roche Ag |
Improvements to next-generation target enrichment performance
|
|
EP4685239A1
(en)
|
2022-11-09 |
2026-01-28 |
10X Genomics, Inc. |
Methods, compositions, and kits for determining the location of multiple analytes in a biological sample
|
|
GB202308392D0
(en)
|
2023-06-06 |
2023-07-19 |
Fu Guoliang |
Methods, compositions, and kits for preparing library and targeted sequencing
|
|
JP2026524816A
(ja)
|
2023-06-14 |
2026-07-24 |
エフ． ホフマン－ラ ロシュ アーゲー |
加速された５－ホルミルシトシンのマーキングおよび核酸メチル化シーケンシングにおける使用
|
|
EP4750913A1
(en)
|
2023-07-26 |
2026-06-03 |
Caribou Biosciences, Inc. |
In vitro validation methods for cd19-targeting cell therapies
|
|
EP4791894A1
(en)
|
2023-10-13 |
2026-08-19 |
Roche Sequencing Solutions, Inc. |
Amplification-free target enrichment workflow for direct detection of nucleic acid modifications
|
|
WO2025193609A1
(en)
|
2024-03-11 |
2025-09-18 |
Caribou Biosciences, Inc. |
Methods and compositions for cost-effective assessment of nucleic acid transcripts and isoforms in cells
|
|
WO2025212586A1
(en)
|
2024-04-02 |
2025-10-09 |
Roche Sequencing Solutions, Inc. |
High throughput inramolecular consensus reads
|
|
WO2025210056A1
(en)
|
2024-04-03 |
2025-10-09 |
Roche Sequencing Solutions, Inc. |
In vitro amplification of dna methylation patterns
|
|
WO2025231432A1
(en)
|
2024-05-03 |
2025-11-06 |
Caribou Biosciences, Inc. |
In vivo gene editing with crispr systems
|
|
WO2025240460A2
(en)
|
2024-05-14 |
2025-11-20 |
Roche Molecular Systems, Inc. |
Assay for detection of mutations conferring resistance to treatment with an immunotherapeutic agent
|
|
WO2026082489A1
(en)
|
2024-10-18 |
2026-04-23 |
F. Hoffmann-La Roche Ag |
Universal pcr to boost molecule recovery in cell free dna library preparation and target enrichment workflows
|
|
WO2026087220A1
(en)
|
2024-10-22 |
2026-04-30 |
F. Hoffmann-La Roche Ag |
Preparation of dna libraries for next generation sequencing using y-adapters modified with phosphorothioate bonds
|
|
WO2026093331A1
(en)
|
2024-10-28 |
2026-05-07 |
F. Hoffmann-La Roche Ag |
Hairpin adapter constructs and primers to generate next-generation sequencing library molecules
|