JP2016533708A5 - - Google Patents
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- Publication number
- JP2016533708A5 JP2016533708A5 JP2016516945A JP2016516945A JP2016533708A5 JP 2016533708 A5 JP2016533708 A5 JP 2016533708A5 JP 2016516945 A JP2016516945 A JP 2016516945A JP 2016516945 A JP2016516945 A JP 2016516945A JP 2016533708 A5 JP2016533708 A5 JP 2016533708A5
- Authority
- JP
- Japan
- Prior art keywords
- nucleic acid
- oligonucleotide
- ezh2
- detecting
- mutation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361888660P | 2013-10-09 | 2013-10-09 | |
| US61/888,660 | 2013-10-09 | ||
| PCT/EP2014/071372 WO2015052147A1 (en) | 2013-10-09 | 2014-10-07 | Methods and compositions for detecting mutation in the human ezh2 gene |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016533708A JP2016533708A (ja) | 2016-11-04 |
| JP2016533708A5 true JP2016533708A5 (enExample) | 2017-11-16 |
| JP6619332B2 JP6619332B2 (ja) | 2019-12-11 |
Family
ID=51663175
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016516945A Active JP6619332B2 (ja) | 2013-10-09 | 2014-10-07 | ヒトｅｚｈ２遺伝子中の変異を検出するための方法及び組成物 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US10260102B2 (enExample) |
| EP (1) | EP3055422B1 (enExample) |
| JP (1) | JP6619332B2 (enExample) |
| CN (1) | CN105593378B (enExample) |
| CA (1) | CA2923706C (enExample) |
| ES (1) | ES2705573T3 (enExample) |
| WO (1) | WO2015052147A1 (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2923706C (en) | 2013-10-09 | 2020-08-25 | F. Hoffmann-La Roche Ag | Methods and compositions for detecting mutation in the human ezh2 gene |
| BR112016029492A2 (pt) | 2014-06-17 | 2017-10-17 | Eisai R&D Man Co Ltd | método para tratamento de linfoma não hodgkin |
| WO2016187394A1 (en) * | 2015-05-19 | 2016-11-24 | Van Wijnen Andre J | Methods and materials for promoting bone formation |
| JP2019500623A (ja) | 2015-11-05 | 2019-01-10 | エピザイム，インコーポレイティド | ヒストンｈ３メチル化ステータスをモニターするためのフローサイトメトリー |
| WO2017132518A1 (en) * | 2016-01-29 | 2017-08-03 | Epizyme, Inc. | Combination therapy for treating cancer |
| US11147819B2 (en) | 2016-06-17 | 2021-10-19 | Epizyme, Inc. | EZH2 inhibitors for treating cancer |
| WO2018076060A1 (en) | 2016-10-26 | 2018-05-03 | Genea Ip Holdings Pty Ltd | Improved generation of muscle lineage cells and therapeutic uses thereof |
| CN112226513B (zh) * | 2020-10-29 | 2022-02-01 | 华中科技大学 | 一种检测ezh2基因可变剪切位点突变的引物、试剂盒及应用 |
| CN116479122A (zh) * | 2022-11-28 | 2023-07-25 | 江苏省人民医院（南京医科大学第一附属医院） | 一种人ezh2基因y646位点突变数字pcr检测试剂盒 |
| CN120624641A (zh) * | 2025-02-20 | 2025-09-12 | 宁波熙宁检测技术有限公司 | 一种用于检测ezh2基因突变的核酸组合物、试剂盒及检测方法 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5981176A (en) | 1992-06-17 | 1999-11-09 | City Of Hope | Method of detecting and discriminating between nucleic acid sequences |
| DE69827060T2 (de) | 1997-03-20 | 2005-03-24 | F. Hoffmann-La Roche Ag | Modifizierte Primer |
| WO2001042498A1 (en) | 1999-12-10 | 2001-06-14 | Toyo Boseki Kabushiki Kaisha | Method of detecting nucleotide polymorphism |
| CA2528669A1 (en) * | 2003-06-09 | 2005-01-20 | The Regents Of The University Of Michigan | Compositions and methods for treating and diagnosing cancer |
| JP2009247231A (ja) | 2008-04-02 | 2009-10-29 | Olympus Corp | 標的塩基判別方法 |
| WO2010046067A1 (en) | 2008-10-20 | 2010-04-29 | Roche Diagnostics Gmbh | Improved allele-specific amplification |
| US20100143901A1 (en) | 2008-12-09 | 2010-06-10 | Roche Molecular Systems, Inc. | Nuclease-Free Real-Time Detection of Nucleic Acids |
| CN101993934A (zh) | 2009-08-10 | 2011-03-30 | 芮屈生物技术（上海）有限公司 | 一种ezh2基因的原位杂交检测试剂盒及其检测方法和应用 |
| BR112014007603A2 (pt) * | 2011-09-30 | 2017-06-13 | Glaxosmithkline Llc | métodos de tratamento do câncer |
| WO2013086639A1 (en) * | 2011-12-14 | 2013-06-20 | British Columbia Cancer Agency Branch | Mutations indicative of weaver syndrome |
| CA2923706C (en) | 2013-10-09 | 2020-08-25 | F. Hoffmann-La Roche Ag | Methods and compositions for detecting mutation in the human ezh2 gene |
-
2014
- 2014-10-07 CA CA2923706A patent/CA2923706C/en active Active
- 2014-10-07 EP EP14781520.3A patent/EP3055422B1/en active Active
- 2014-10-07 CN CN201480055312.0A patent/CN105593378B/zh active Active
- 2014-10-07 US US14/508,618 patent/US10260102B2/en active Active
- 2014-10-07 JP JP2016516945A patent/JP6619332B2/ja active Active
- 2014-10-07 ES ES14781520T patent/ES2705573T3/es active Active
- 2014-10-07 WO PCT/EP2014/071372 patent/WO2015052147A1/en not_active Ceased
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