|
PT90657B
(pt)
|
1988-05-27 |
1995-03-01 |
Ortho Pharma Corp |
Processo para a preparacao de peptidos que bloqueiam a ligacao de hiv-1 a proteina cd4 receptora
|
|
JPH0768273B2
(ja)
*
|
1988-12-02 |
1995-07-26 |
カルピス食品工業株式会社 |
抗hivペプチド
|
|
US5530101A
(en)
|
1988-12-28 |
1996-06-25 |
Protein Design Labs, Inc. |
Humanized immunoglobulins
|
|
IL162181A
(en)
|
1988-12-28 |
2006-04-10 |
Pdl Biopharma Inc |
A method of producing humanized immunoglubulin, and polynucleotides encoding the same
|
|
WO1990013562A1
(en)
|
1989-05-02 |
1990-11-15 |
Genelabs Incorporated |
Chemically modified cd4 peptide fragments having anti-retroviral properties
|
|
GB8912497D0
(en)
|
1989-05-31 |
1989-07-19 |
Cobbold Stephen P |
Monoclonal antibodies
|
|
US5690933A
(en)
|
1989-05-31 |
1997-11-25 |
Glaxo Wellcome Inc. |
Monoclonal antibodies for inducing tolerance
|
|
GB8928874D0
(en)
|
1989-12-21 |
1990-02-28 |
Celltech Ltd |
Humanised antibodies
|
|
US20020099179A1
(en)
|
1989-12-21 |
2002-07-25 |
Linda K. Jolliffe |
Cdr-grafted antibodies
|
|
US5859205A
(en)
|
1989-12-21 |
1999-01-12 |
Celltech Limited |
Humanised antibodies
|
|
HUT60768A
(en)
|
1990-03-16 |
1992-10-28 |
Sandoz Ag |
Process for producing cd25 fixing molecules
|
|
US7084260B1
(en)
|
1996-10-10 |
2006-08-01 |
Genpharm International, Inc. |
High affinity human antibodies and human antibodies against human antigens
|
|
DE69126301T2
(de)
|
1990-11-27 |
1998-01-02 |
Biogen, Inc., Cambridge, Mass. |
Hiv-induzierte synzytien blockierender anti-cd-4-antikörper
|
|
US7192584B2
(en)
|
1991-03-18 |
2007-03-20 |
Centocor, Inc. |
Methods of treating psoriasis with anti-TNF antibodies
|
|
US6136310A
(en)
|
1991-07-25 |
2000-10-24 |
Idec Pharmaceuticals Corporation |
Recombinant anti-CD4 antibodies for human therapy
|
|
JPH05244982A
(ja)
|
1991-12-06 |
1993-09-24 |
Sumitomo Chem Co Ltd |
擬人化b−b10
|
|
US5777085A
(en)
|
1991-12-20 |
1998-07-07 |
Protein Design Labs, Inc. |
Humanized antibodies reactive with GPIIB/IIIA
|
|
IL101769A
(en)
|
1992-05-03 |
2007-02-11 |
Yeda Res & Dev |
Modulation of TNF receptor action
|
|
WO1995009652A1
(en)
|
1993-10-06 |
1995-04-13 |
The Kennedy Institute For Rheumatology |
Treatment of autoimmune and inflammatory disorders
|
|
US6270766B1
(en)
|
1992-10-08 |
2001-08-07 |
The Kennedy Institute Of Rheumatology |
Anti-TNF antibodies and methotrexate in the treatment of arthritis and crohn's disease
|
|
AU5152293A
(en)
|
1992-10-08 |
1994-05-09 |
Kennedy Institute Of Rheumatology, The |
Treatment of autoimmune and inflammatory disorders
|
|
ES2159529T5
(es)
|
1993-03-05 |
2011-03-09 |
Bayer Corporation |
Anticuerpos monoclonales humanos anti-tnf alfa.
|
|
EP0631783A1
(en)
|
1993-06-03 |
1995-01-04 |
Mitsubishi Chemical Corporation |
Antiviral combinations of 2',3'-di-deoxyribonucleosides with 6-benzyl-1-ethoxymethyl-5-substituted uracil derivatives
|
|
US20020068057A1
(en)
|
1994-03-10 |
2002-06-06 |
Marc Feldmann |
Treatment of autoimmune and inflammatory disorders
|
|
ES2196150T3
(es)
|
1995-05-18 |
2003-12-16 |
Ortho Mcneil Pharm Inc |
Induccion de tolerancia inmunologica por el uso de anticuerpos anti-cd4 que no inducen deplecion.
|
|
DK0929578T3
(da)
|
1996-02-09 |
2003-08-25 |
Abbott Lab Bermuda Ltd |
Humane antistoffer, der binder human TNFalfa
|
|
US20010056066A1
(en)
|
1996-07-26 |
2001-12-27 |
Smithkline Beecham Corporation |
Method of treating immune cell mediated systemic diseases
|
|
AU4563197A
(en)
|
1996-10-01 |
1998-04-24 |
Celltech Therapeutics Limited |
Pharmaceutical products containing protein-tyrosine kinase inhibitors and anti-cd4 antibodies
|
|
US6037454A
(en)
|
1996-11-27 |
2000-03-14 |
Genentech, Inc. |
Humanized anti-CD11a antibodies
|
|
DE19722888A1
(de)
|
1997-05-28 |
1998-12-03 |
Thomas Prof Dr Huenig |
Human-CD28 spezifische monoklonale Antikörper zur antigenunspezifischen Aktivierung von T-Lymphozyten
|
|
WO2000058362A1
(en)
|
1999-03-26 |
2000-10-05 |
Human Genome Sciences, Inc. |
Neutrokine-alpha binding proteins and methods based thereon
|
|
CA2375912C
(en)
|
1999-06-09 |
2014-03-11 |
Immunomedics, Inc. |
Immunotherapy of autoimmune disorders using antibodies which target b-cells
|
|
US7304127B2
(en)
|
1999-08-27 |
2007-12-04 |
United States Of America As Represented By The Secretary, Department Of Health And Human Services |
Polypeptides that bind HIV gp120 and related nucleic acids, antibodies, compositions, and methods of use
|
|
WO2001016182A2
(en)
*
|
1999-08-27 |
2001-03-08 |
The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
POLYPEPTIDES THAT BIND HIV gp120 AND RELATED NUCLEIC ACIDS, ANTIBODIES, COMPOSITIONS, AND METHODS OF USE
|
|
CA2410786A1
(en)
|
2000-06-02 |
2001-12-13 |
Regents Of The University Of Minnesota |
Immunotherapeutic method to prevent islet cell rejection
|
|
CA2422076A1
(en)
|
2000-09-18 |
2002-03-21 |
Idec Pharmaceutical Corporation |
Combination therapy for treatment of autoimmune diseases using b cell depleting/immunoregulatory antibody combination
|
|
DE10050935A1
(de)
|
2000-10-11 |
2002-05-02 |
Tegenero Gmbh |
Verwendung CD28 spezifischer monoklonaler Antikörper zur Stimulation von Blutzellen, welche kein CD28 tragen
|
|
ATE481097T1
(de)
|
2001-01-16 |
2010-10-15 |
Vascular Therapies Llc |
Implantierbare vorrichtung enthaltend resorbierbares matrixmaterial und antiproliferative wirkstoffe zur vorbeugung oder behandlung von versagen vaskulärer hämodialysezugänge und anderer vaskulärer transplantate
|
|
CA2440649A1
(en)
|
2001-03-07 |
2002-09-19 |
Children's Medical Center Corporation |
Method to screen peptide display libraries using minicell display
|
|
EP1241249A1
(en)
|
2001-03-12 |
2002-09-18 |
Gerold Schuler |
CD4+CD25+regulatory T cells from human blood
|
|
WO2002085405A2
(en)
|
2001-04-24 |
2002-10-31 |
Merck Patent Gmbh |
COMBINATION THERAPY USING ANTI-ANGIOGENIC AGENTS AND TNF$g(a)
|
|
AU2002302848C8
(en)
|
2001-06-14 |
2010-02-04 |
Cambridge Enterprise Limited |
CD4-specific antibody TRX1 and uses therefor
|
|
GB2376466A
(en)
|
2001-06-14 |
2002-12-18 |
Mark Frewin |
TRX1 antibody
|
|
US7541443B2
(en)
|
2001-06-14 |
2009-06-02 |
Tolerrx, Inc. |
Anti-CD4 antibodies
|
|
EP1451224B1
(de)
|
2001-12-04 |
2012-08-15 |
TheraMAB LLC |
Peptid oder protein enthaltend ein c'-d loop der cd28 rezeptorfamilie
|
|
DE10212108A1
(de)
|
2002-03-13 |
2003-10-02 |
Tegenero Ag |
Verwendung einer an CD28 bindenden Wirksubstanz zur Herstellung einer pharmazeutischen Zusammensetzung
|
|
DE10230223A1
(de)
|
2002-07-04 |
2004-01-22 |
Tegenero Ag |
Mikropartikel mit CD28-spezifischen monoklonalen Antikörpern
|
|
WO2004024097A2
(en)
|
2002-09-16 |
2004-03-25 |
Genentech, Inc. |
Compositions and methods for the treatment of immune related diseases
|
|
US7388079B2
(en)
|
2002-11-27 |
2008-06-17 |
The Regents Of The University Of California |
Delivery of pharmaceutical agents via the human insulin receptor
|
|
US7501494B2
(en)
|
2003-01-15 |
2009-03-10 |
United Biomedical, Inc. |
Designed deimmunized monoclonal antibodies for protection against HIV exposure and treatment of HIV infection
|
|
EP1460088A1
(en)
|
2003-03-21 |
2004-09-22 |
Biotest AG |
Humanized anti-CD4 antibody with immunosuppressive properties
|
|
EP2062916A3
(en)
|
2003-04-09 |
2009-08-19 |
Genentech, Inc. |
Therapy of autoimmune disease in a patient with an inadequate response to a TNF-Alpha inhibitor
|
|
GB0314461D0
(en)
|
2003-06-20 |
2003-07-23 |
Isis Innovation |
Suppression of transplant rejection
|
|
US7691970B2
(en)
|
2003-08-25 |
2010-04-06 |
Pieris Ag |
Muteins of a bilin-binding protein with affinity for a given target
|
|
EP1600164A3
(de)
|
2003-09-22 |
2006-05-17 |
TeGenero AG |
Verwendung einer an CD28 bindenden Wirksubstanz zur Herstellung einer Pharmazeutischen Zusammensetzung mit dosisabhängiger Wirkung
|
|
DE10352900A1
(de)
|
2003-11-11 |
2005-06-16 |
Tegenero Ag |
Verwendung einer an CD28 bindenden Wirksubstanz zur Herstellung einer pharmazeutischen Zusammensetzung zur Behandlung von B-CLL
|
|
US20060002921A1
(en)
|
2004-06-22 |
2006-01-05 |
Tolerrx, Inc. |
Optimized dosing with anti-CD4 antibodies for tolerance induction in primates
|
|
US7410772B2
(en)
|
2004-07-02 |
2008-08-12 |
Genentech, Inc. |
Compositions and methods for treatment of non-Hodgkin's lymphoma
|
|
WO2006035876A1
(ja)
|
2004-09-29 |
2006-04-06 |
Kowa Co., Ltd. |
関節リウマチの予防及び/又は治療薬
|
|
PT2171060E
(pt)
|
2004-11-11 |
2013-11-18 |
Theramab Llc |
Anticorpo anti-cd28 superagonista
|
|
WO2006055077A2
(en)
|
2004-11-12 |
2006-05-26 |
The University Of North Carolina At Charlotte |
Modulation of cd4+ t cell responses by a tick saliva protein, salp15 and polypeptides derived therefrom
|
|
DE102004063494A1
(de)
|
2004-12-23 |
2006-07-13 |
Tegenero Ag |
Antikörper
|
|
JP4730733B2
(ja)
|
2005-05-02 |
2011-07-20 |
国立大学法人京都大学 |
4型葉酸受容体の発現を指標とした制御性t細胞の検出方法、及び免疫賦活剤
|
|
AU2006267090B2
(en)
|
2005-07-11 |
2013-03-07 |
Provention Bio, Inc. |
Methods for the treatment of autoimmune disorders using immunosuppressive monoclonal antibodies with reduced toxicity
|
|
US9309315B2
(en)
|
2005-08-18 |
2016-04-12 |
Genmab A/S |
Therapy with CD4 binding peptides and radiation
|
|
CA2619298C
(en)
|
2005-08-26 |
2017-07-04 |
Glycart Biotechnology Ag |
Modified antigen binding molecules with altered cell signaling activity
|
|
AU2007248444B2
(en)
|
2006-01-05 |
2012-10-25 |
Genentech, Inc. |
Anti-EphB4 antibodies and methods using same
|
|
WO2007109052A2
(en)
|
2006-03-16 |
2007-09-27 |
Genentech, Inc. |
Methods of treating lupus using cd4 antibodies
|
|
JP2009529915A
(ja)
*
|
2006-03-20 |
2009-08-27 |
ゾーマ テクノロジー リミテッド |
ガストリン物質に対して特異的なヒト抗体および方法
|
|
US20090208471A1
(en)
|
2006-04-07 |
2009-08-20 |
Yun Theodore J |
Isolation and Use of Human Regulatory T Cells
|
|
MX2008013508A
(es)
|
2006-04-21 |
2008-10-31 |
Novartis Ag |
Composiciones farmaceuticas de anticuerpos antagonistas anti-cd40.
|
|
WO2007135684A2
(en)
*
|
2006-05-22 |
2007-11-29 |
Hadasit Medical Research Services & Development Limited |
Method of treatment of anti-cd4 autoimmunity
|
|
ES2593789T3
(es)
|
2007-02-01 |
2016-12-13 |
Universitätsmedizin Der Johannes Gutenberg-Universität Mainz |
Activación específica de una célula T reguladora y su uso para el tratamiento del asma, enfermedades alérgicas, enfermedades autoinmunes, rechazo de injertos y para la inducción de tolerancia
|
|
TWI570135B
(zh)
|
2007-04-27 |
2017-02-11 |
建南德克公司 |
高效、穩定且非免疫抑制之抗-cd4抗體
|
|
BRPI0909048A2
(pt)
|
2008-03-13 |
2015-11-24 |
Biotest Ag |
composição farmacêutica, e, método de tratamento de uma doença autoimune
|
|
HUE028962T2
(en)
*
|
2008-03-13 |
2017-01-30 |
Biotest Ag |
Active ingredient for treating disease
|
|
ES2610327T3
(es)
|
2008-03-13 |
2017-04-27 |
Biotest Ag |
Régimen de dosificación de anticuerpos anti-CD4 para el tratamiento de enfermedades autoinmunitarias
|
|
EP2101173A1
(en)
|
2008-03-14 |
2009-09-16 |
Vivalis |
In vitro method to determine whether a drug candidate active against a target protein is active against a variant of said protein
|
|
WO2010022341A1
(en)
|
2008-08-21 |
2010-02-25 |
The United State Of America, As Represented By The Secretary, Department Of Health And Human Services |
Methods of enriching and using regulatory t cells
|
|
ES2335381B1
(es)
|
2008-09-24 |
2011-02-28 |
Fundacio Institut De Recerca De L'hospital Universitari Vall D'hebron |
Metodo in vitro y kit para el pronostico o prediccion de la respuestapor parte de pacientes con artritis reumatoide al tratamiento con agentes bloqueantes del factor tnfalfa.
|
|
KR20110061630A
(ko)
*
|
2008-09-29 |
2011-06-09 |
바이오테스트 아게 |
질병 치료용 조성물
|
|
ES2351456B1
(es)
|
2009-06-24 |
2011-11-28 |
Fundacio Institut De Recerca De L'hospital Universitari Vall D'hebron |
Metodo in vitro para el pronostico o prediccion de la respuesta por parte de pacientes con artritis reumatoide al tratamiento con agentes que reconocen el receptor de membrana cd20 de los linfocitos b
|
|
JP5399219B2
(ja)
|
2009-11-24 |
2014-01-29 |
株式会社ケイティーバイオ |
関節リウマチに対するヒト型抗TNFα抗体薬の薬効予測方法、及び薬効予測装置
|
|
WO2011158798A1
(ja)
|
2010-06-14 |
2011-12-22 |
国立大学法人山口大学 |
乾癬治療効果の経過観察及び早期の予測方法並びにそれらに使用するキット
|