JP2012143232A5 - - Google Patents
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- Publication number
- JP2012143232A5 JP2012143232A5 JP2012021947A JP2012021947A JP2012143232A5 JP 2012143232 A5 JP2012143232 A5 JP 2012143232A5 JP 2012021947 A JP2012021947 A JP 2012021947A JP 2012021947 A JP2012021947 A JP 2012021947A JP 2012143232 A5 JP2012143232 A5 JP 2012143232A5
- Authority
- JP
- Japan
- Prior art keywords
- chain variable
- variable region
- seq
- monoclonal antibody
- heavy chain
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000427 antigen Substances 0.000 claims 12
- 102000036639 antigens Human genes 0.000 claims 12
- 108091007433 antigens Proteins 0.000 claims 12
- 239000012634 fragment Substances 0.000 claims 12
- 210000004027 cell Anatomy 0.000 claims 7
- 238000004519 manufacturing process Methods 0.000 claims 4
- 239000004480 active ingredient Substances 0.000 claims 3
- 125000003275 alpha amino acid group Chemical group 0.000 claims 2
- 238000012258 culturing Methods 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 2
- 102000040430 polynucleotide Human genes 0.000 claims 2
- 108091033319 polynucleotide Proteins 0.000 claims 2
- 239000002157 polynucleotide Substances 0.000 claims 2
- 229940124597 therapeutic agent Drugs 0.000 claims 2
- 208000023275 Autoimmune disease Diseases 0.000 claims 1
- 101000984199 Homo sapiens Leukocyte immunoglobulin-like receptor subfamily A member 4 Proteins 0.000 claims 1
- 102000006992 Interferon-alpha Human genes 0.000 claims 1
- 108010047761 Interferon-alpha Proteins 0.000 claims 1
- 102000014150 Interferons Human genes 0.000 claims 1
- 108010050904 Interferons Proteins 0.000 claims 1
- 239000003153 chemical reaction reagent Substances 0.000 claims 1
- 210000004544 dc2 Anatomy 0.000 claims 1
- 238000001514 detection method Methods 0.000 claims 1
- 102000047610 human LILRA4 Human genes 0.000 claims 1
- 239000003112 inhibitor Substances 0.000 claims 1
- 229940079322 interferon Drugs 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 201000000596 systemic lupus erythematosus Diseases 0.000 claims 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2012021947A JP5420688B2 (ja) | 2005-12-20 | 2012-02-03 | 抗ｉｌｔ７抗体 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2005366465 | 2005-12-20 | ||
| JP2005366465 | 2005-12-20 | ||
| JP2012021947A JP5420688B2 (ja) | 2005-12-20 | 2012-02-03 | 抗ｉｌｔ７抗体 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007551124A Division JP5020828B2 (ja) | 2005-12-20 | 2006-12-20 | 抗ｉｌｔ７抗体 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012143232A JP2012143232A (ja) | 2012-08-02 |
| JP2012143232A5 true JP2012143232A5 (https=) | 2013-04-25 |
| JP5420688B2 JP5420688B2 (ja) | 2014-02-19 |
Family
ID=38188642
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007551124A Active JP5020828B2 (ja) | 2005-12-20 | 2006-12-20 | 抗ｉｌｔ７抗体 |
| JP2012021947A Active JP5420688B2 (ja) | 2005-12-20 | 2012-02-03 | 抗ｉｌｔ７抗体 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007551124A Active JP5020828B2 (ja) | 2005-12-20 | 2006-12-20 | 抗ｉｌｔ７抗体 |
Country Status (29)
| Country | Link |
|---|---|
| US (6) | US8084585B2 (https=) |
| EP (4) | EP3441403A1 (https=) |
| JP (2) | JP5020828B2 (https=) |
| KR (3) | KR101526934B1 (https=) |
| CN (5) | CN101379089B (https=) |
| AU (1) | AU2006328470B2 (https=) |
| BR (1) | BRPI0620141B1 (https=) |
| CA (2) | CA2634116C (https=) |
| CY (3) | CY1114227T1 (https=) |
| DK (3) | DK2913343T3 (https=) |
| ES (3) | ES2526079T3 (https=) |
| HK (1) | HK1218126A1 (https=) |
| HR (2) | HRP20130494T1 (https=) |
| HU (1) | HUE039865T2 (https=) |
| IL (1) | IL192266A (https=) |
| LT (1) | LT2913343T (https=) |
| ME (1) | ME02111B (https=) |
| MX (1) | MX2008007682A (https=) |
| NZ (3) | NZ616992A (https=) |
| PL (3) | PL1964852T3 (https=) |
| PT (3) | PT2913343T (https=) |
| RS (2) | RS52860B (https=) |
| RU (2) | RU2456298C2 (https=) |
| SG (2) | SG170749A1 (https=) |
| SI (3) | SI2913343T1 (https=) |
| TR (1) | TR201816574T4 (https=) |
| UA (1) | UA97946C2 (https=) |
| WO (1) | WO2007072866A1 (https=) |
| ZA (1) | ZA200805850B (https=) |
Families Citing this family (44)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2892724B1 (fr) * | 2005-11-02 | 2008-01-04 | Lab Francais Du Fractionnement | Anticorps cytotoxiques diriges contre des anticorps inhibiteurs du facteur viii. |
| WO2011060076A1 (en) * | 2009-11-10 | 2011-05-19 | Amgen Inc. | Anti-c-mpl antibodies |
| WO2011063237A2 (en) * | 2009-11-19 | 2011-05-26 | Oncomed Pharmaceuticals, Inc. | Jagged-binding agents and uses thereof |
| CN103037900B (zh) | 2010-02-24 | 2016-04-06 | 伊缪诺金公司 | 叶酸受体1抗体与免疫缀合物以及其用途 |
| EP3085387A1 (en) * | 2010-04-26 | 2016-10-26 | Abraxis BioScience, LLC | Sparc binding antibodies and uses thereof |
| IL281714B2 (en) | 2011-04-01 | 2023-11-01 | Immunogen Inc | Methods for increasing the effectiveness of FOLR1 cancer therapy |
| DK2828284T3 (da) | 2012-03-20 | 2019-06-11 | Biogen Ma Inc | Jcv-neutraliserende antistoffer |
| ES2706173T3 (es) * | 2012-03-20 | 2019-03-27 | Biogen Ma Inc | Anticuerpos de neutralización de JCV |
| JP6403166B2 (ja) * | 2012-08-03 | 2018-10-10 | ダナ−ファーバー キャンサー インスティテュート， インコーポレイテッド | 単一抗原抗ｐｄ−ｌ１およびｐｄ−ｌ２二重結合抗体およびその使用方法 |
| HUE049693T2 (hu) | 2012-08-31 | 2020-10-28 | Immunogen Inc | Diagnosztikai ASSAY-k és készletek a folát receptor 1 kimutatására |
| AU2014312086B2 (en) | 2013-08-30 | 2020-03-12 | Immunogen, Inc. | Antibodies and assays for detection of folate receptor 1 |
| US10035847B2 (en) | 2013-10-02 | 2018-07-31 | The Rockefeller University | Amyloid protofibril antibodies and methods of use thereof |
| US10294301B2 (en) * | 2013-12-24 | 2019-05-21 | Astellas Pharma Inc. | Anti-human BDCA-2 antibody |
| IL313511A (en) | 2014-11-12 | 2024-08-01 | Seagen Inc | Compounds acting on glycans and methods of using them |
| MX382582B (es) * | 2015-03-18 | 2025-03-13 | Seagen Inc | Anticuerpos contra cúmulo de diferenciación 48 (cd48) y sus conjugados. |
| ES2887273T3 (es) * | 2015-06-29 | 2021-12-22 | Immunogen Inc | Anticuerpos anti-CD123 y conjugados y derivados de los mismos |
| AU2016323968B2 (en) | 2015-09-17 | 2023-07-06 | Immunogen, Inc. | Therapeutic combinations comprising anti-FOLR1 immunoconjugates |
| EP3373969A4 (en) | 2015-11-12 | 2019-08-14 | Siamab Therapeutics, Inc. | GLYCANINTERAGING COMPOUNDS AND METHOD OF USE |
| MX2018006249A (es) * | 2015-11-19 | 2018-11-09 | Abbvie Stemcentrx Llc | Nuevos anticuerpos anti-emr2 y metodos de uso. |
| WO2017130060A1 (en) | 2016-01-26 | 2017-08-03 | Ciriello Christopher John | Automated dental treatment system |
| WO2017132486A1 (en) * | 2016-01-27 | 2017-08-03 | Siamab Therapeutics, Inc. | Compositions and methods for targeting cancer stem cells |
| MX2018010445A (es) | 2016-03-01 | 2019-10-17 | Yissum Res Dev Co Of Hebrew Univ Jerusalem Ltd | Anticuerpos especificos del receptor de poliovirus humano (rvp). |
| RU2756109C2 (ru) * | 2016-03-10 | 2021-09-28 | Виела Байо, Инк. | Связывающие ilt7 молекулы и способы их применения |
| JP6967528B2 (ja) | 2016-04-04 | 2021-11-17 | バイオベラティブ ユーエスエー インコーポレイテッド | 抗補体Ｂｂ因子抗体及びその使用 |
| KR102653141B1 (ko) | 2017-03-03 | 2024-04-01 | 씨젠 인크. | 글리칸-상호작용 화합물 및 사용 방법 |
| KR20200042937A (ko) * | 2017-08-30 | 2020-04-24 | 페인스 테라퓨틱스 인코포레이티드 | 항-lag-3 항체 및 이의 용도 |
| CN111527105B (zh) | 2017-10-11 | 2024-10-25 | 美国比奥维拉迪维股份有限公司 | 诱导补体活性的方法 |
| JP7194481B2 (ja) * | 2017-11-17 | 2022-12-22 | メルク・シャープ・アンド・ドーム・エルエルシー | 免疫グロブリン様転写産物３（ｉｌｔ３）に特異的な抗体およびその使用 |
| KR20200103751A (ko) | 2017-12-20 | 2020-09-02 | 라디뮨 테라퓨틱스 인코포레이티드 | 센트린-1에 대한 항체, 이의 제조 방법, 및 용도 |
| WO2019141092A1 (zh) * | 2018-01-18 | 2019-07-25 | 四川科伦博泰生物医药股份有限公司 | 抗lag-3抗体及其用途 |
| US20210251721A1 (en) | 2018-05-10 | 2021-08-19 | Cyberdontics (Usa), Inc. | Automated dental drill |
| TW202003576A (zh) * | 2018-05-10 | 2020-01-16 | 美商艾博視訊有限公司 | 活化cd40之單株抗體及其用途 |
| MX2022001841A (es) * | 2019-08-12 | 2022-08-17 | Biond Biologics Ltd | Anticuerpos contra ilt2 y uso de los mismos. |
| WO2021070181A1 (en) | 2019-10-08 | 2021-04-15 | Nectin Therapeutics Ltd. | Antibodies against the poliovirus receptor (pvr) and uses thereof |
| WO2021113702A1 (en) * | 2019-12-06 | 2021-06-10 | Viela Bio, Inc. | Methods of treatment using ilt7 binding proteins |
| KR20230004686A (ko) | 2020-04-20 | 2023-01-06 | 젠자임 코포레이션 | 인간화 항-보체 인자 Bb 항체 및 그의 용도 |
| WO2022051516A1 (en) | 2020-09-03 | 2022-03-10 | Cyberdontics (Usa), Inc. | Method and apparatus for cna analysis of tooth anatomy |
| IL308132A (en) | 2021-05-04 | 2023-12-01 | Viela Bio Inc | Methods of treatment of autoimmune disorders using ilt7 binding proteins |
| AU2023312911A1 (en) | 2022-07-27 | 2025-01-02 | Viela Bio, Inc. | Formulations comprising an immunoglobulin-like transcript 7 (ilt7)-binding protein |
| CN115819604B (zh) * | 2022-09-09 | 2025-04-15 | 季华实验室 | 抗双链dna抗体、核苷酸片段、磁珠及提取外周血游离dna的方法 |
| KR20250160358A (ko) * | 2023-03-16 | 2025-11-12 | 인매진 피티이. 엘티디. | Ilt7-표적화 항체 및 그의 용도 |
| CN116948032B (zh) * | 2023-09-19 | 2023-12-12 | 汇智生物技术(苏州)有限公司 | 人源cd4单克隆抗体及其制备方法和应用 |
| CN120098124A (zh) * | 2023-12-05 | 2025-06-06 | 苏州普乐康医药科技有限公司 | 一种抗bdca-2抗体及其制备方法和应用 |
| WO2026002175A1 (zh) * | 2024-06-27 | 2026-01-02 | 无锡徕特康生物科技有限公司 | 靶向ilt7和cd89的髓细胞衔接子抗体及其用途 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA952797B (en) * | 1994-04-12 | 1996-10-07 | Res Dev Foundation | Method of treating auto-immune diseases using type one interferons |
| US6107090A (en) * | 1996-05-06 | 2000-08-22 | Cornell Research Foundation, Inc. | Treatment and diagnosis of prostate cancer with antibodies to extracellur PSMA domains |
| HU229520B1 (en) * | 1999-02-12 | 2014-01-28 | Scripps Research Inst | Methods for treatment of tumors and metastases using a combination of anti-angiogenic and immuno therapies |
| TWI335336B (https=) * | 2000-02-10 | 2011-01-01 | Abbott Gmbh & Co Kg | |
| US6897067B2 (en) * | 2000-11-03 | 2005-05-24 | Regents Of The University Of Michigan | Surface transfection and expression procedure |
| US20040241167A1 (en) * | 2001-06-25 | 2004-12-02 | Nicole Suciu-Foca | Ilt3 and ilt4-related compositons and methods |
| AU2002318944A1 (en) * | 2001-08-01 | 2003-02-17 | Coley Pharmaceutical Gmbh | Methods and compositions relating to plasmacytoid dendritic cells |
| KR20050035511A (ko) * | 2001-10-13 | 2005-04-18 | 아스테리온 리미티드 | 폴리펩타이드들을 포함하는 글리코실포스파티딜이노시톨 |
| US7217796B2 (en) * | 2002-05-24 | 2007-05-15 | Schering Corporation | Neutralizing human anti-IGFR antibody |
| AU2003252328A1 (en) | 2002-08-01 | 2004-02-23 | Ginkgo Biomedical Research Institute Co., Ltd. | Method of detecting mouse interferon-producing cells |
| AU2003289716A1 (en) * | 2002-09-12 | 2004-04-30 | Incyte Corporation | Molecules for diagnostics and therapeutics |
| EP2157524A3 (en) | 2003-09-03 | 2010-12-08 | GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES | Methods for identifying, diagnosing, and predicting survival of lymphomas |
| GB0417487D0 (en) | 2004-08-05 | 2004-09-08 | Novartis Ag | Organic compound |
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2006
- 2006-12-20 HR HRP20130494TT patent/HRP20130494T1/hr unknown
- 2006-12-20 ES ES12168586.1T patent/ES2526079T3/es active Active
- 2006-12-20 CN CN200680053131XA patent/CN101379089B/zh active Active
- 2006-12-20 ES ES06842945T patent/ES2416716T3/es active Active
- 2006-12-20 CN CN201911002539.XA patent/CN110776566B/zh active Active
- 2006-12-20 JP JP2007551124A patent/JP5020828B2/ja active Active
- 2006-12-20 LT LTEP14186905.7T patent/LT2913343T/lt unknown
- 2006-12-20 PT PT14186905T patent/PT2913343T/pt unknown
- 2006-12-20 KR KR1020087017667A patent/KR101526934B1/ko active Active
- 2006-12-20 RU RU2008129715/10A patent/RU2456298C2/ru active
- 2006-12-20 RS RS20130256A patent/RS52860B/sr unknown
- 2006-12-20 SG SG201102016-1A patent/SG170749A1/en unknown
- 2006-12-20 PL PL06842945T patent/PL1964852T3/pl unknown
- 2006-12-20 TR TR2018/16574T patent/TR201816574T4/tr unknown
- 2006-12-20 SI SI200632299T patent/SI2913343T1/sl unknown
- 2006-12-20 PT PT68429455T patent/PT1964852E/pt unknown
- 2006-12-20 NZ NZ616992A patent/NZ616992A/en unknown
- 2006-12-20 SI SI200631864T patent/SI2532681T1/sl unknown
- 2006-12-20 RS RS20140678A patent/RS53752B1/sr unknown
- 2006-12-20 KR KR1020147004977A patent/KR101585532B1/ko active Active
- 2006-12-20 CA CA2634116A patent/CA2634116C/en not_active Expired - Fee Related
- 2006-12-20 EP EP18187761.4A patent/EP3441403A1/en not_active Withdrawn
- 2006-12-20 MX MX2008007682A patent/MX2008007682A/es active IP Right Grant
- 2006-12-20 HU HUE14186905A patent/HUE039865T2/hu unknown
- 2006-12-20 CN CN202510875177.4A patent/CN120718150A/zh active Pending
- 2006-12-20 PL PL12168586T patent/PL2532681T3/pl unknown
- 2006-12-20 DK DK14186905.7T patent/DK2913343T3/en active
- 2006-12-20 SI SI200631608T patent/SI1964852T1/sl unknown
- 2006-12-20 DK DK12168586.1T patent/DK2532681T3/en active
- 2006-12-20 CN CN2013102707794A patent/CN103360492A/zh active Pending
- 2006-12-20 EP EP06842945.5A patent/EP1964852B1/en active Active
- 2006-12-20 BR BRPI0620141-5A patent/BRPI0620141B1/pt active IP Right Grant
- 2006-12-20 PL PL14186905T patent/PL2913343T3/pl unknown
- 2006-12-20 DK DK06842945.5T patent/DK1964852T3/da active
- 2006-12-20 SG SG10201602095PA patent/SG10201602095PA/en unknown
- 2006-12-20 EP EP12168586.1A patent/EP2532681B1/en active Active
- 2006-12-20 ME MEP-2014-157A patent/ME02111B/me unknown
- 2006-12-20 AU AU2006328470A patent/AU2006328470B2/en not_active Ceased
- 2006-12-20 US US12/064,957 patent/US8084585B2/en active Active
- 2006-12-20 ES ES14186905T patent/ES2699428T3/es active Active
- 2006-12-20 PT PT121685861T patent/PT2532681E/pt unknown
- 2006-12-20 KR KR1020157004466A patent/KR101624587B1/ko active Active
- 2006-12-20 WO PCT/JP2006/325391 patent/WO2007072866A1/ja not_active Ceased
- 2006-12-20 CN CN201510296327.2A patent/CN105111311B/zh not_active Expired - Fee Related
- 2006-12-20 EP EP14186905.7A patent/EP2913343B1/en active Active
- 2006-12-20 UA UAA200809418A patent/UA97946C2/ru unknown
- 2006-12-20 CA CA2994756A patent/CA2994756C/en active Active
- 2006-12-20 NZ NZ569910A patent/NZ569910A/en not_active IP Right Cessation
- 2006-12-20 NZ NZ599683A patent/NZ599683A/xx not_active IP Right Cessation
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2008
- 2008-06-18 IL IL192266A patent/IL192266A/en active IP Right Grant
- 2008-07-04 ZA ZA200805850A patent/ZA200805850B/xx unknown
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2011
- 2011-11-22 US US13/302,291 patent/US8470992B2/en active Active
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2012
- 2012-02-03 JP JP2012021947A patent/JP5420688B2/ja active Active
- 2012-03-28 RU RU2012112046/10A patent/RU2599450C2/ru active
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2013
- 2013-06-07 US US13/912,335 patent/US20130259872A1/en not_active Abandoned
- 2013-07-02 CY CY20131100538T patent/CY1114227T1/el unknown
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2014
- 2014-12-16 HR HRP20141226TT patent/HRP20141226T1/hr unknown
- 2014-12-17 CY CY20141101048T patent/CY1116031T1/el unknown
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2015
- 2015-12-16 US US14/971,303 patent/US20160130343A1/en not_active Abandoned
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2016
- 2016-05-30 HK HK16106102.4A patent/HK1218126A1/zh unknown
- 2016-10-31 US US15/339,080 patent/US20170204179A1/en not_active Abandoned
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2018
- 2018-11-07 CY CY20181101167T patent/CY1121294T1/el unknown
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2020
- 2020-02-24 US US16/799,441 patent/US20200339682A1/en active Pending