|
FR7461M
(OSRAM)
|
1968-06-19 |
1970-01-05 |
|
|
|
GB1355961A
(en)
*
|
1970-02-27 |
1974-06-12 |
Wellcome Found |
Preparation of immunosuppressive antilymphocytic serum
|
|
CH594444A5
(OSRAM)
*
|
1972-12-04 |
1978-01-13 |
Gerd Birrenbach |
|
|
DK143689C
(da)
|
1975-03-20 |
1982-03-15 |
J Kreuter |
Fremgangsmaade til fremstilling af en adsorberet vaccine
|
|
US4756907A
(en)
|
1978-10-17 |
1988-07-12 |
Stolle Research & Development Corp. |
Active/passive immunization of the internal female reproductive organs
|
|
US4946929A
(en)
|
1983-03-22 |
1990-08-07 |
Massachusetts Institute Of Technology |
Bioerodible articles useful as implants and prostheses having predictable degradation rates
|
|
US6309669B1
(en)
|
1984-03-16 |
2001-10-30 |
The United States Of America As Represented By The Secretary Of The Army |
Therapeutic treatment and prevention of infections with a bioactive materials encapsulated within a biodegradable-biocompatible polymeric matrix
|
|
US4638045A
(en)
|
1985-02-19 |
1987-01-20 |
Massachusetts Institute Of Technology |
Non-peptide polyamino acid bioerodible polymers
|
|
US4631211A
(en)
|
1985-03-25 |
1986-12-23 |
Scripps Clinic & Research Foundation |
Means for sequential solid phase organic synthesis and methods using the same
|
|
US4806621A
(en)
|
1986-01-21 |
1989-02-21 |
Massachusetts Institute Of Technology |
Biocompatible, bioerodible, hydrophobic, implantable polyimino carbonate article
|
|
JPS63122620A
(ja)
*
|
1986-11-12 |
1988-05-26 |
Sanraku Inc |
ポリ乳酸マイクロスフエア及びその製造方法
|
|
US5759830A
(en)
|
1986-11-20 |
1998-06-02 |
Massachusetts Institute Of Technology |
Three-dimensional fibrous scaffold containing attached cells for producing vascularized tissue in vivo
|
|
CA1340581C
(en)
|
1986-11-20 |
1999-06-08 |
Joseph P. Vacanti |
Chimeric neomorphogenesis of organs by controlled cellular implantation using artificial matrices
|
|
US5736372A
(en)
|
1986-11-20 |
1998-04-07 |
Massachusetts Institute Of Technology |
Biodegradable synthetic polymeric fibrous matrix containing chondrocyte for in vivo production of a cartilaginous structure
|
|
FR2608988B1
(fr)
|
1986-12-31 |
1991-01-11 |
Centre Nat Rech Scient |
Procede de preparation de systemes colloidaux dispersibles d'une substance, sous forme de nanoparticules
|
|
US5912017A
(en)
|
1987-05-01 |
1999-06-15 |
Massachusetts Institute Of Technology |
Multiwall polymeric microspheres
|
|
US5229490A
(en)
|
1987-05-06 |
1993-07-20 |
The Rockefeller University |
Multiple antigen peptide system
|
|
US5019379A
(en)
|
1987-07-31 |
1991-05-28 |
Massachusetts Institute Of Technology |
Unsaturated polyanhydrides
|
|
US6130082A
(en)
|
1988-05-05 |
2000-10-10 |
American Cyanamid Company |
Recombinant flagellin vaccines
|
|
US4929624A
(en)
*
|
1989-03-23 |
1990-05-29 |
Minnesota Mining And Manufacturing Company |
Olefinic 1H-imidazo(4,5-c)quinolin-4-amines
|
|
US5010167A
(en)
|
1989-03-31 |
1991-04-23 |
Massachusetts Institute Of Technology |
Poly(amide-and imide-co-anhydride) for biological application
|
|
US5114703A
(en)
*
|
1989-05-30 |
1992-05-19 |
Alliance Pharmaceutical Corp. |
Percutaneous lymphography using particulate fluorocarbon emulsions
|
|
US5733572A
(en)
*
|
1989-12-22 |
1998-03-31 |
Imarx Pharmaceutical Corp. |
Gas and gaseous precursor filled microspheres as topical and subcutaneous delivery vehicles
|
|
GB9016885D0
(en)
*
|
1990-08-01 |
1990-09-12 |
Scras |
Sustained release pharmaceutical compositions
|
|
US5389640A
(en)
|
1991-03-01 |
1995-02-14 |
Minnesota Mining And Manufacturing Company |
1-substituted, 2-substituted 1H-imidazo[4,5-c]quinolin-4-amines
|
|
JP3296817B2
(ja)
|
1991-04-02 |
2002-07-02 |
バイオテック・オーストラリア・ピーティーワイ・リミテッド |
微粒子に適した経口配布系
|
|
US5811447A
(en)
|
1993-01-28 |
1998-09-22 |
Neorx Corporation |
Therapeutic inhibitor of vascular smooth muscle cells
|
|
US6235313B1
(en)
*
|
1992-04-24 |
2001-05-22 |
Brown University Research Foundation |
Bioadhesive microspheres and their use as drug delivery and imaging systems
|
|
WO1994002068A1
(en)
|
1992-07-21 |
1994-02-03 |
The General Hospital Corporation |
System of drug delivery to the lymphatic tissues
|
|
GB9216082D0
(en)
|
1992-07-28 |
1992-09-09 |
Univ Nottingham |
Lymphatic delivery composition
|
|
US6608201B2
(en)
|
1992-08-28 |
2003-08-19 |
3M Innovative Properties Company |
Process for preparing 1-substituted, 2-substituted 1H-imidazo[4,5-c]quinolin-4-amines
|
|
FR2695563B1
(fr)
*
|
1992-09-11 |
1994-12-02 |
Pasteur Institut |
Microparticules portant des antigènes et leur utilisation pour l'induction de réponses humorales ou cellulaires.
|
|
AU4932493A
(en)
|
1992-09-25 |
1994-04-26 |
Dynagen, Inc. |
An immunobooster for delayed release of immunogen
|
|
US5399665A
(en)
|
1992-11-05 |
1995-03-21 |
Massachusetts Institute Of Technology |
Biodegradable polymers for cell transplantation
|
|
DE69418699T2
(de)
|
1993-01-11 |
1999-09-30 |
Dana-Farber Cancer Institute, Boston |
Induktion der antworten zytotoxischer t-lymphozyten
|
|
US5512600A
(en)
|
1993-01-15 |
1996-04-30 |
Massachusetts Institute Of Technology |
Preparation of bonded fiber structures for cell implantation
|
|
US5514378A
(en)
|
1993-02-01 |
1996-05-07 |
Massachusetts Institute Of Technology |
Biocompatible polymer membranes and methods of preparation of three dimensional membrane structures
|
|
DE69411154T2
(de)
|
1993-02-22 |
1998-10-22 |
Alza Corp., Palo Alto, Calif. |
Mittel zur oralen gabe von wirkstoffen
|
|
JPH08508721A
(ja)
|
1993-03-17 |
1996-09-17 |
シリカゲル ゲス．エム．ビー．エイチ |
超常磁性粒子、その製法及びその用途
|
|
US5543158A
(en)
|
1993-07-23 |
1996-08-06 |
Massachusetts Institute Of Technology |
Biodegradable injectable nanoparticles
|
|
US5565215A
(en)
|
1993-07-23 |
1996-10-15 |
Massachusettes Institute Of Technology |
Biodegradable injectable particles for imaging
|
|
WO1995003035A1
(en)
|
1993-07-23 |
1995-02-02 |
Massachusetts Institute Of Technology |
Polymerized liposomes with enhanced stability for oral delivery
|
|
US5798340A
(en)
|
1993-09-17 |
1998-08-25 |
Gilead Sciences, Inc. |
Nucleotide analogs
|
|
US5500161A
(en)
|
1993-09-21 |
1996-03-19 |
Massachusetts Institute Of Technology And Virus Research Institute |
Method for making hydrophobic polymeric microparticles
|
|
JP2930421B2
(ja)
|
1994-02-28 |
1999-08-03 |
メディノヴァ メディカル コンサルティング ゲゼルシャフト ミット ベシュレンクテル ハフツング |
薬剤組成物、その製造方法及びその使用方法
|
|
GB9412273D0
(en)
*
|
1994-06-18 |
1994-08-10 |
Univ Nottingham |
Administration means
|
|
DK0772619T4
(da)
|
1994-07-15 |
2011-02-21 |
Univ Iowa Res Found |
Immunmodulatoriske oligonukleotider
|
|
US6207646B1
(en)
|
1994-07-15 |
2001-03-27 |
University Of Iowa Research Foundation |
Immunostimulatory nucleic acid molecules
|
|
US6239116B1
(en)
|
1994-07-15 |
2001-05-29 |
University Of Iowa Research Foundation |
Immunostimulatory nucleic acid molecules
|
|
US6007845A
(en)
|
1994-07-22 |
1999-12-28 |
Massachusetts Institute Of Technology |
Nanoparticles and microparticles of non-linear hydrophilic-hydrophobic multiblock copolymers
|
|
US5716404A
(en)
|
1994-12-16 |
1998-02-10 |
Massachusetts Institute Of Technology |
Breast tissue engineering
|
|
CA2207961A1
(en)
|
1995-01-05 |
1996-07-11 |
Robert J. Levy |
Surface-modified nanoparticles and method of making and using same
|
|
US6123727A
(en)
|
1995-05-01 |
2000-09-26 |
Massachusetts Institute Of Technology |
Tissue engineered tendons and ligaments
|
|
WO1997004747A1
(en)
|
1995-07-27 |
1997-02-13 |
Dunn James M |
Drug delivery systems for macromolecular drugs
|
|
CA2230494A1
(en)
|
1995-08-31 |
1997-03-06 |
Alkermes Controlled Therapeutics Inc. |
Composition for sustained release of an agent
|
|
US6095148A
(en)
|
1995-11-03 |
2000-08-01 |
Children's Medical Center Corporation |
Neuronal stimulation using electrically conducting polymers
|
|
US5902599A
(en)
|
1996-02-20 |
1999-05-11 |
Massachusetts Institute Of Technology |
Biodegradable polymer networks for use in orthopedic and dental applications
|
|
US5874064A
(en)
|
1996-05-24 |
1999-02-23 |
Massachusetts Institute Of Technology |
Aerodynamically light particles for pulmonary drug delivery
|
|
US5922695A
(en)
|
1996-07-26 |
1999-07-13 |
Gilead Sciences, Inc. |
Antiviral phosphonomethyoxy nucleotide analogs having increased oral bioavarilability
|
|
US6368598B1
(en)
|
1996-09-16 |
2002-04-09 |
Jcrt Radiation Oncology Support Services, Inc. |
Drug complex for treatment of metastatic prostate cancer
|
|
US6039969A
(en)
|
1996-10-25 |
2000-03-21 |
3M Innovative Properties Company |
Immune response modifier compounds for treatment of TH2 mediated and related diseases
|
|
US6042820A
(en)
|
1996-12-20 |
2000-03-28 |
Connaught Laboratories Limited |
Biodegradable copolymer containing α-hydroxy acid and α-amino acid units
|
|
WO1998037919A1
(en)
|
1997-02-28 |
1998-09-03 |
University Of Iowa Research Foundation |
USE OF NUCLEIC ACIDS CONTAINING UNMETHYLATED CpG DINUCLEOTIDE IN THE TREATMENT OF LPS-ASSOCIATED DISORDERS
|
|
ATE441432T1
(de)
|
1997-03-10 |
2009-09-15 |
Ottawa Hospital Res Inst |
Verwendung von nicht-methyliertem cpg dinukleotid in kombination mit aluminium als adjuvantien
|
|
US6211159B1
(en)
|
1997-04-11 |
2001-04-03 |
University Of Toronto |
Flagellin gene, FlaC of campylobacter
|
|
US6060082A
(en)
|
1997-04-18 |
2000-05-09 |
Massachusetts Institute Of Technology |
Polymerized liposomes targeted to M cells and useful for oral or mucosal drug delivery
|
|
DE69838294T2
(de)
|
1997-05-20 |
2009-08-13 |
Ottawa Health Research Institute, Ottawa |
Verfahren zur Herstellung von Nukleinsäurekonstrukten
|
|
US5837752A
(en)
|
1997-07-17 |
1998-11-17 |
Massachusetts Institute Of Technology |
Semi-interpenetrating polymer networks
|
|
US6989435B2
(en)
|
1997-09-11 |
2006-01-24 |
Cambridge University Technical Services Ltd. |
Compounds and methods to inhibit or augment an inflammatory response
|
|
DE19745950A1
(de)
|
1997-10-17 |
1999-04-22 |
Dds Drug Delivery Service Ges |
Arzneistoffträgerpartikel für die gewebespezifische Arzneistoffapplikation
|
|
US6329381B1
(en)
|
1997-11-28 |
2001-12-11 |
Sumitomo Pharmaceuticals Company, Limited |
Heterocyclic compounds
|
|
US6197229B1
(en)
|
1997-12-12 |
2001-03-06 |
Massachusetts Institute Of Technology |
Method for high supercoiled DNA content microspheres
|
|
US6254890B1
(en)
|
1997-12-12 |
2001-07-03 |
Massachusetts Institute Of Technology |
Sub-100nm biodegradable polymer spheres capable of transporting and releasing nucleic acids
|
|
FR2775435B1
(fr)
|
1998-02-27 |
2000-05-26 |
Bioalliance Pharma |
Nanoparticules comprenant au moins un polymere et au moins un compose apte a complexer un ou plusieurs principes actifs
|
|
US6232287B1
(en)
|
1998-03-13 |
2001-05-15 |
The Burnham Institute |
Molecules that home to various selected organs or tissues
|
|
US6632922B1
(en)
|
1998-03-19 |
2003-10-14 |
The Regents Of The University Of California |
Methods and compositions for controlled polypeptide synthesis
|
|
US6506577B1
(en)
|
1998-03-19 |
2003-01-14 |
The Regents Of The University Of California |
Synthesis and crosslinking of catechol containing copolypeptides
|
|
US6686446B2
(en)
|
1998-03-19 |
2004-02-03 |
The Regents Of The University Of California |
Methods and compositions for controlled polypeptide synthesis
|
|
DE69935507T2
(de)
|
1998-04-03 |
2007-12-06 |
University Of Iowa Research Foundation |
Verfahren und produkte zur stimulierung des immunsystems mittels immunotherapeutischer oligonukleotide und zytokine
|
|
WO1999056755A1
(en)
|
1998-05-06 |
1999-11-11 |
University Of Iowa Research Foundation |
Methods for the prevention and treatment of parasitic infections and related diseases using cpg oligonucleotides
|
|
DE19827164A1
(de)
|
1998-06-18 |
1999-12-23 |
Merck Patent Gmbh |
Katalytisch Titan(IV)-oxid vermittelte geminale symmetrische Dialkylierung von Carbonsäureamiden
|
|
US6242589B1
(en)
|
1998-07-14 |
2001-06-05 |
Isis Pharmaceuticals, Inc. |
Phosphorothioate oligonucleotides having modified internucleoside linkages
|
|
DK1100468T3
(da)
|
1998-07-29 |
2006-07-31 |
Chiron Corp |
Mikropartikler med adsorbent-overflader, fremgangsmåder til fremstilling af disse samt anvendelser deraf
|
|
DE19839214C1
(de)
*
|
1998-08-28 |
2000-05-25 |
Aventis Res & Tech Gmbh & Co |
Verfahren zur Herstellung von sphärischen Mikropartikeln mit glatter Oberfläche, die ganz oder teilweise aus mindestens einem wasserunlöslichen linearen Polysaccharid bestehen, sowie mit diesem Verfahren erhältliche Mikropartikel und deren Verwendung
|
|
US6306640B1
(en)
|
1998-10-05 |
2001-10-23 |
Genzyme Corporation |
Melanoma antigenic peptides
|
|
CA2348871C
(en)
|
1998-11-02 |
2009-04-14 |
John G. Devane |
Multiparticulate modified release composition
|
|
US7521068B2
(en)
|
1998-11-12 |
2009-04-21 |
Elan Pharma International Ltd. |
Dry powder aerosols of nanoparticulate drugs
|
|
US7238711B1
(en)
|
1999-03-17 |
2007-07-03 |
Cambridge University Technical Services Ltd. |
Compounds and methods to inhibit or augment an inflammatory response
|
|
US6444192B1
(en)
|
1999-02-05 |
2002-09-03 |
The Regents Of The University Of California |
Diagnostic imaging of lymph structures
|
|
US7238368B2
(en)
|
1999-04-23 |
2007-07-03 |
Alza Corporation |
Releasable linkage and compositions containing same
|
|
IL146055A0
(en)
|
1999-04-23 |
2002-07-25 |
Alza Corp |
Conjugate having a cleavable linkage for use in a liposome
|
|
US6800296B1
(en)
|
1999-05-19 |
2004-10-05 |
Massachusetts Institute Of Technology |
Modification of surfaces using biological recognition events
|
|
US6815170B1
(en)
|
1999-06-30 |
2004-11-09 |
John Wayne Cancer Institute |
Methods for lymph node identification
|
|
EP1202671A4
(en)
*
|
1999-08-13 |
2004-11-10 |
Point Biomedical Corp |
MICROPARTICLES USEFUL AS ULTRASONIC CONTRAST AGENTS FOR THE LYMPHATIC SYSTEM
|
|
CA2391534A1
(en)
|
1999-11-15 |
2001-05-25 |
Drug Innovation & Design, Inc. |
Selective cellular targeting: multifunctional delivery vehicles
|
|
EP1294930B1
(en)
|
2000-01-13 |
2011-03-30 |
Nanosphere, Inc. |
Nanoparticles having oligonucleotides attached thereto and uses therefor
|
|
US20050032733A1
(en)
|
2001-05-18 |
2005-02-10 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (SiNA)
|
|
US8202979B2
(en)
|
2002-02-20 |
2012-06-19 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid
|
|
US20050020525A1
(en)
*
|
2002-02-20 |
2005-01-27 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)
|
|
JP4751556B2
(ja)
|
2000-02-28 |
2011-08-17 |
ジーンシーグス， インコーポレイテッド |
ナノカプセルカプセル化システムおよび方法
|
|
US20030129251A1
(en)
|
2000-03-10 |
2003-07-10 |
Gary Van Nest |
Biodegradable immunomodulatory formulations and methods for use thereof
|
|
US7129222B2
(en)
*
|
2000-03-10 |
2006-10-31 |
Dynavax Technologies Corporation |
Immunomodulatory formulations and methods for use thereof
|
|
US7192725B2
(en)
|
2000-05-19 |
2007-03-20 |
University Of Toronto |
Flagellin gene, flaC of Campylobacter
|
|
WO2002100325A2
(en)
|
2000-10-13 |
2002-12-19 |
Ligocyte Pharmaceuticals, Inc. |
Polyvalent nanoparticles
|
|
GB0025414D0
(en)
|
2000-10-16 |
2000-11-29 |
Consejo Superior Investigacion |
Nanoparticles
|
|
WO2002055185A2
(en)
|
2000-10-19 |
2002-07-18 |
Eidgenoess Tech Hochschule |
Block copolymers for multifunctional self-assembled systems
|
|
US7592008B2
(en)
|
2000-11-20 |
2009-09-22 |
The Board Of Trustees Of The University Of Illinois, A Body Corporate And Politic Of The State Of Illinois |
Membrane scaffold proteins
|
|
US7097837B2
(en)
|
2001-02-19 |
2006-08-29 |
Pharmexa A/S |
Synthetic vaccine agents
|
|
US20030175950A1
(en)
|
2001-05-29 |
2003-09-18 |
Mcswiggen James A. |
RNA interference mediated inhibition of HIV gene expression using short interfering RNA
|
|
US7314624B2
(en)
|
2001-06-05 |
2008-01-01 |
The Regents Of The University Of Michigan |
Nanoemulsion vaccines
|
|
NZ530315A
(en)
|
2001-07-10 |
2007-01-26 |
Corixa Corp |
Compositions and methods for delivery of proteins and adjuvants encapsulated in microspheres
|
|
WO2003014316A2
(en)
|
2001-08-07 |
2003-02-20 |
Dynavax Technologies Corporation |
Immunomodulatory compositions, formulations, and methods for use thereof
|
|
US6818732B2
(en)
|
2001-08-30 |
2004-11-16 |
The Regents Of The University Of California |
Transition metal initiators for controlled poly (beta-peptide) synthesis from beta-lactam monomers
|
|
US8088388B2
(en)
|
2002-02-14 |
2012-01-03 |
United Biomedical, Inc. |
Stabilized synthetic immunogen delivery system
|
|
US7501134B2
(en)
*
|
2002-02-20 |
2009-03-10 |
Novartis Vaccines And Diagnostics, Inc. |
Microparticles with adsorbed polypeptide-containing molecules
|
|
US20030232013A1
(en)
|
2002-02-22 |
2003-12-18 |
Gary Sieckman |
Therapeutic and diagnostic targeting of cancers cells with tumor homing peptides
|
|
US7635463B2
(en)
*
|
2002-02-27 |
2009-12-22 |
Pharmain Corporation |
Compositions for delivery of therapeutics and other materials
|
|
ES2543710T3
(es)
|
2002-04-04 |
2015-08-21 |
Zoetis Belgium S.A. |
Oligorribonucleótidos inmunoestimulantes que contienen G y U
|
|
US20040038303A1
(en)
*
|
2002-04-08 |
2004-02-26 |
Unger Gretchen M. |
Biologic modulations with nanoparticles
|
|
US20080233181A1
(en)
|
2002-04-12 |
2008-09-25 |
Nagy Jon O |
Nanoparticle adjuvants for sub-unit vaccines
|
|
US7285289B2
(en)
*
|
2002-04-12 |
2007-10-23 |
Nagy Jon O |
Nanoparticle vaccines
|
|
DE60320780D1
(de)
*
|
2002-04-22 |
2008-06-19 |
Univ Florida |
Funktionalisierte nanopartikel und verwendungsverfahren
|
|
DK2226316T3
(en)
*
|
2002-05-30 |
2016-04-11 |
Scripps Research Inst |
Copper catalyzed ligation of azides and acetylenes
|
|
US20040092470A1
(en)
*
|
2002-06-18 |
2004-05-13 |
Leonard Sherry A. |
Dry powder oligonucleotide formualtion, preparation and its uses
|
|
WO2004005325A2
(en)
|
2002-07-10 |
2004-01-15 |
The Ohio State University Research Foundation |
Antigen-polymer compositions
|
|
KR101228376B1
(ko)
*
|
2002-07-18 |
2013-01-31 |
사이토스 바이오테크놀로지 아게 |
합텐-캐리어 컨쥬게이트 및 그의 용도
|
|
US7488792B2
(en)
|
2002-08-28 |
2009-02-10 |
Burnham Institute For Medical Research |
Collagen-binding molecules that selectively home to tumor vasculature and methods of using same
|
|
US20060189554A1
(en)
|
2002-09-24 |
2006-08-24 |
Russell Mumper |
Nanoparticle-Based vaccine delivery system containing adjuvant
|
|
US7008411B1
(en)
|
2002-09-30 |
2006-03-07 |
Advanced Cardiovascular Systems, Inc. |
Method and apparatus for treating vulnerable plaque
|
|
NO20024755D0
(no)
|
2002-10-03 |
2002-10-03 |
Amersham Health As |
Metode
|
|
SE0203687D0
(sv)
|
2002-12-13 |
2002-12-13 |
Ian Harwigsson Med Adagit Fa |
Pharmaceutical Porous Particles
|
|
US20040156846A1
(en)
|
2003-02-06 |
2004-08-12 |
Triton Biosystems, Inc. |
Therapy via targeted delivery of nanoscale particles using L6 antibodies
|
|
JP4509999B2
(ja)
|
2003-02-17 |
2010-07-21 |
ブルクハルト，ペーター |
医薬送達及び抗原提示システムとしてのペプチドナノ粒子
|
|
US20040191215A1
(en)
|
2003-03-25 |
2004-09-30 |
Michael Froix |
Compositions for induction of a therapeutic response
|
|
CA2518223A1
(en)
|
2003-03-26 |
2004-10-07 |
Ltt Bio-Pharma Co., Ltd. |
Intravenous nanoparticles for targeting drug delivery and sustained drug release
|
|
ZA200507562B
(en)
*
|
2003-03-26 |
2006-11-29 |
Cytos Biotechnology Ag |
HIV-peptide-carrier-conjugates
|
|
US7731967B2
(en)
|
2003-04-30 |
2010-06-08 |
Novartis Vaccines And Diagnostics, Inc. |
Compositions for inducing immune responses
|
|
US7727969B2
(en)
|
2003-06-06 |
2010-06-01 |
Massachusetts Institute Of Technology |
Controlled release nanoparticle having bound oligonucleotide for targeted delivery
|
|
US20060182793A1
(en)
|
2003-07-22 |
2006-08-17 |
Cytos Biotechnology Ag |
Cpg-packaged liposomes
|
|
US20050042298A1
(en)
|
2003-08-20 |
2005-02-24 |
Pardridge William M. |
Immunonanoparticles
|
|
EP2481422A3
(en)
|
2003-09-03 |
2013-04-03 |
Dendritherapeutics, Inc. |
Multiplex vaccines
|
|
US7943179B2
(en)
|
2003-09-23 |
2011-05-17 |
Massachusetts Institute Of Technology |
pH triggerable polymeric particles
|
|
US20080160089A1
(en)
*
|
2003-10-14 |
2008-07-03 |
Medivas, Llc |
Vaccine delivery compositions and methods of use
|
|
JP2007514519A
(ja)
|
2003-10-20 |
2007-06-07 |
ウィリアム・マーシュ・ライス・ユニバーシティ |
ポリマー及び帯電ナノ粒子からなるマイクロカプセルを製造する方法
|
|
JP2007512355A
(ja)
|
2003-11-21 |
2007-05-17 |
アルザ コーポレイション |
開裂性のｐｅｇで表面修飾されたリポソーム−ｄｎａ複合体で媒介される遺伝子送達
|
|
WO2005055949A2
(en)
*
|
2003-12-09 |
2005-06-23 |
The Children's Hospital Of Philadelphia |
Sustained release preparations composed of biocompatible complex microparticles
|
|
KR20120105062A
(ko)
*
|
2003-12-19 |
2012-09-24 |
더 유니버시티 오브 노쓰 캐롤라이나 엣 채플 힐 |
소프트 또는 임프린트 리소그래피를 이용하여 분리된 마이크로- 및 나노- 구조를 제작하는 방법
|
|
WO2005065418A2
(en)
|
2003-12-31 |
2005-07-21 |
Board Of Regents, The University Of Texas System |
Compositions and methods of use of targeting peptides for diagnosis and therapy
|
|
US20070087986A1
(en)
*
|
2004-01-26 |
2007-04-19 |
Brett Premack |
Compositions and methods for enhancing immunity by chemoattractant adjuvants
|
|
CA2555390C
(en)
|
2004-02-19 |
2014-08-05 |
Coley Pharmaceutical Group, Inc. |
Immunostimulatory viral rna oligonucleotides
|
|
EP1735010A4
(en)
*
|
2004-04-09 |
2008-08-27 |
3M Innovative Properties Co |
METHODS, COMPOSITIONS AND PREPARATIONS FOR ADMINISTRATION OF IMMUNE RESPONSE MODIFIERS (MRI)
|
|
ES2246695B1
(es)
|
2004-04-29 |
2007-05-01 |
Instituto Cientifico Y Tecnologico De Navarra, S.A. |
Composicion estimuladora de la respuesta inmunitaria que comprende nanoparticulas a base de un copolimero de metil vinil eter y anhidrido maleico.
|
|
US20060017339A1
(en)
*
|
2004-06-03 |
2006-01-26 |
Lalit Chordia |
Brushless canned motor
|
|
CA2569590C
(en)
|
2004-06-11 |
2014-04-01 |
Riken |
Drug having regulatory cell ligand contained in liposome
|
|
US7713550B2
(en)
|
2004-06-15 |
2010-05-11 |
Andrx Corporation |
Controlled release sodium valproate formulation
|
|
JP2008512350A
(ja)
|
2004-07-01 |
2008-04-24 |
イェール ユニバーシティ |
標的化され、そして高密度で薬物が負荷されるポリマー性物質
|
|
WO2006014579A2
(en)
|
2004-07-08 |
2006-02-09 |
The Regents Of California |
Enhancing class i antigen presentation with synthetic sequences
|
|
US8017151B2
(en)
*
|
2004-09-07 |
2011-09-13 |
Board Of Regents Of The University Of Nebraska By And Behalf Of The University Of Nebraska Medical Center |
Amphiphilic polymer-protein conjugates and methods of use thereof
|
|
CN1692943A
(zh)
|
2004-09-17 |
2005-11-09 |
四川大学 |
CpG DNA分子抗感染免疫制剂的制备和应用
|
|
GB0421296D0
(en)
|
2004-09-24 |
2004-10-27 |
Angiogene Pharm Ltd |
Bioreductively-activated prodrugs
|
|
US9079765B2
(en)
*
|
2004-10-01 |
2015-07-14 |
Midatech Ltd. |
Nanoparticles comprising antigens and adjuvants, and immunogenic structures
|
|
CN101438252A
(zh)
|
2004-10-07 |
2009-05-20 |
爱莫里大学 |
多功能纳米粒子共轭体及其应用
|
|
US9492400B2
(en)
|
2004-11-04 |
2016-11-15 |
Massachusetts Institute Of Technology |
Coated controlled release polymer particles as efficient oral delivery vehicles for biopharmaceuticals
|
|
US9789171B2
(en)
|
2004-11-05 |
2017-10-17 |
The General Hospital Corporation |
Anti-fugetactic agents for the treatment of ovarian cancer
|
|
AU2005334819B2
(en)
|
2004-11-15 |
2011-11-24 |
Novartis Vaccines And Diagnostics Inc. |
Immunogenic compositions containing anthrax antigen, biodegradable polymer microparticles, and polynucleotide-containing immunological adjuvant
|
|
US20060111271A1
(en)
|
2004-11-24 |
2006-05-25 |
Cerny Erich H |
Active and passive immunization against pharmacologically active hapten molecules using a synthetic carrier compound composed of similar elements
|
|
CA2590768A1
(en)
|
2004-12-14 |
2006-06-22 |
Alnylam Pharmaceuticals, Inc. |
Rnai modulation of mll-af4 and uses thereof
|
|
US20060257359A1
(en)
|
2005-02-28 |
2006-11-16 |
Cedric Francois |
Modifying macrophage phenotype for treatment of disease
|
|
CN101189339A
(zh)
|
2005-03-22 |
2008-05-28 |
美得思达健康有限公司 |
诊断和治疗心血管疾病的递送系统和方法
|
|
US20080305161A1
(en)
|
2005-04-13 |
2008-12-11 |
Pfizer Inc |
Injectable depot formulations and methods for providing sustained release of nanoparticle compositions
|
|
CA2609788A1
(en)
|
2005-04-26 |
2006-11-02 |
Coley Pharmaceutical Gmbh |
Modified oligoribonucleotide analogs with enhanced immunostimulatory activity
|
|
MX2007013760A
(es)
|
2005-05-04 |
2008-01-28 |
Noxxon Pharma Ag |
Uso novedoso de spiegelmers.
|
|
EP1893661B1
(en)
|
2005-05-10 |
2012-01-18 |
Emory University |
Strategies for delivery of active agents using micelles and particles
|
|
ZA200709239B
(en)
*
|
2005-05-10 |
2009-04-29 |
Balaban Naomi |
Compositions for administering RNAIII-inhibiting peptides
|
|
EP1904553A4
(en)
|
2005-07-06 |
2013-04-24 |
Molly S Shoichet |
METHOD OF IMMOBILIZING BIOMOLECULE ON POLYMERS INVOLVING FAST TYPE CHEMICAL REACTIONS
|
|
CA2618807C
(en)
|
2005-08-12 |
2015-01-06 |
University Health Network |
Methods and devices for lymphatic targeting
|
|
US8765181B2
(en)
*
|
2005-09-09 |
2014-07-01 |
Beijing Diacrid Medical Technology Co., Ltd |
Nano anticancer micelles of vinca alkaloids entrapped in polyethylene glycolylated phospholipids
|
|
WO2007062107A2
(en)
|
2005-11-25 |
2007-05-31 |
Coley Pharmaceutical Gmbh |
Immunostimulatory oligoribonucleotides
|
|
WO2008051245A2
(en)
|
2005-12-02 |
2008-05-02 |
Novartis Ag |
Nanoparticles for use in immunogenic compositions
|
|
NZ569741A
(en)
|
2005-12-14 |
2012-02-24 |
Cytos Biotechnology Ag |
Immunostimulatory nucleic acid packaged particles for the treatment of hypersensitivity
|
|
US9267937B2
(en)
|
2005-12-15 |
2016-02-23 |
Massachusetts Institute Of Technology |
System for screening particles
|
|
US7842312B2
(en)
|
2005-12-29 |
2010-11-30 |
Cordis Corporation |
Polymeric compositions comprising therapeutic agents in crystalline phases, and methods of forming the same
|
|
CA2676601A1
(en)
*
|
2006-01-31 |
2007-08-09 |
Medivas, Llc |
Vaccine delivery compositions and methods of use
|
|
US8021689B2
(en)
|
2006-02-21 |
2011-09-20 |
Ecole Polytechnique Federale de Lausanne (“EPFL”) |
Nanoparticles for immunotherapy
|
|
AU2007221154A1
(en)
|
2006-02-24 |
2007-09-07 |
Novartis Ag |
Microparticles containing biodegradable polymer and cationic polysaccharide for use in immunogenic compositions
|
|
ES2776100T3
(es)
|
2006-03-31 |
2020-07-29 |
Massachusetts Inst Technology |
Sistema para el suministro dirigido de agentes terapéuticos
|
|
CA2649149A1
(en)
|
2006-04-11 |
2007-10-25 |
Koko Kosmetikvertrieb Gmbh & Co. Kg |
Nanoparticle containing nicotine and/or cotinine, dispersions, and use thereof
|
|
EP2019691B1
(en)
|
2006-05-15 |
2020-08-12 |
Massachusetts Institute of Technology |
Polymers for functional particles
|
|
US20110052697A1
(en)
*
|
2006-05-17 |
2011-03-03 |
Gwangju Institute Of Science & Technology |
Aptamer-Directed Drug Delivery
|
|
JP5437797B2
(ja)
|
2006-06-12 |
2014-03-12 |
サイトス バイオテクノロジー アーゲー |
Ｒｎａバクテリオファージのウイルス様粒子にオリゴヌクレオチドをパッケージ化するための方法
|
|
US20080014281A1
(en)
|
2006-06-16 |
2008-01-17 |
Florida Atlantic University |
Chitin Micro-Particles As An Adjuvant
|
|
WO2007150030A2
(en)
|
2006-06-23 |
2007-12-27 |
Massachusetts Institute Of Technology |
Microfluidic synthesis of organic nanoparticles
|
|
WO2008019142A2
(en)
|
2006-08-04 |
2008-02-14 |
Massachusetts Institute Of Technology |
Oligonucleotide systems for targeted intracellular delivery
|
|
US20080171059A1
(en)
|
2006-08-07 |
2008-07-17 |
Shanshan Wu Howland |
Methods and compositions for increased priming of t-cells through cross-presentation of exogenous antigens
|
|
AU2007323007A1
(en)
|
2006-08-11 |
2008-05-29 |
Panacea Biotec Limited |
Particles for delivery of active ingredients, process of making and compositions thereof
|
|
WO2008033432A2
(en)
|
2006-09-12 |
2008-03-20 |
Coley Pharmaceutical Group, Inc. |
Immune modulation by chemically modified ribonucleosides and oligoribonucleotides
|
|
EP2077821B1
(en)
|
2006-10-12 |
2019-08-14 |
The University Of Queensland |
Compositions and methods for modulating immune responses
|
|
US20100303723A1
(en)
|
2006-11-20 |
2010-12-02 |
Massachusetts Institute Of Technology |
Drug delivery systems using fc fragments
|
|
US20090093551A1
(en)
|
2006-12-08 |
2009-04-09 |
Bhatia Sangeeta N |
Remotely triggered release from heatable surfaces
|
|
WO2008071774A1
(en)
|
2006-12-14 |
2008-06-19 |
Cytos Biotechnology Ag |
Purification process for coat protein of rna bacteriophages
|
|
US20080149123A1
(en)
*
|
2006-12-22 |
2008-06-26 |
Mckay William D |
Particulate material dispensing hairbrush with combination bristles
|
|
EP2510946B1
(en)
*
|
2007-02-07 |
2015-08-05 |
The Regents of The University of California |
Conjugates of synthetic tlr agonists and uses therefor
|
|
EP2134830A2
(en)
|
2007-02-09 |
2009-12-23 |
Massachusetts Institute of Technology |
Oscillating cell culture bioreactor
|
|
US8889117B2
(en)
|
2007-02-15 |
2014-11-18 |
Yale University |
Modular nanoparticles for adaptable vaccines
|
|
WO2008118861A2
(en)
|
2007-03-23 |
2008-10-02 |
The University Of North Carolina At Chapel Hill |
Discrete size and shape specific organic nanoparticles designed to elicit an immune response
|
|
WO2008121926A1
(en)
|
2007-03-30 |
2008-10-09 |
Particle Sciences, Inc. |
Particle formulations and uses thereof
|
|
US20090074828A1
(en)
*
|
2007-04-04 |
2009-03-19 |
Massachusetts Institute Of Technology |
Poly(amino acid) targeting moieties
|
|
WO2008124634A1
(en)
|
2007-04-04 |
2008-10-16 |
Massachusetts Institute Of Technology |
Polymer-encapsulated reverse micelles
|
|
US20090226525A1
(en)
|
2007-04-09 |
2009-09-10 |
Chimeros Inc. |
Self-assembling nanoparticle drug delivery system
|
|
WO2008127532A1
(en)
|
2007-04-12 |
2008-10-23 |
Emory University |
Novel strategies for delivery of active agents using micelles and particles
|
|
US8394914B2
(en)
|
2007-08-24 |
2013-03-12 |
Board Of Trustees Of Michigan State University |
Functional polyglycolide nanoparticles derived from unimolecular micelles
|
|
US8563738B2
(en)
|
2007-09-18 |
2013-10-22 |
The Scripps Research Institute |
Ligands for copper-catalyzed azide-alkyne cycloaddition reactions
|
|
MX350501B
(es)
|
2007-10-12 |
2017-09-07 |
Massachusetts Inst Technology |
Nanotecnologia de vacuna.
|
|
EP2217930B1
(en)
*
|
2007-10-24 |
2013-03-06 |
Tallinn University Of Technology |
Maldi ms-based high-throughput screening method for substances inhibiting aggregation of alzheimer's amyloid beta peptides
|
|
AU2008335457B2
(en)
*
|
2007-12-07 |
2015-04-16 |
Glaxosmithkline Biologicals S.A. |
Compositions for inducing immune responses
|
|
US8546337B2
(en)
|
2008-02-01 |
2013-10-01 |
Alpha-O-Peptides Ag |
Self-assembling peptide nanoparticles useful as vaccines
|
|
WO2009106999A2
(en)
|
2008-02-28 |
2009-09-03 |
Deutsches Krebsforschungszentrum, Stiftung Des Öffentlichen Rechts |
Hollow nanoparticles and uses thereof
|
|
EP2262480B1
(en)
|
2008-03-04 |
2018-02-14 |
Liquidia Technologies, Inc. |
Immunomodulator particles
|
|
US20090297621A1
(en)
|
2008-06-03 |
2009-12-03 |
Abbott Cardiovascular Systems Inc. |
Microparticles For The Treatment Of Disease
|
|
US8206747B2
(en)
*
|
2008-06-16 |
2012-06-26 |
Bind Biosciences, Inc. |
Drug loaded polymeric nanoparticles and methods of making and using same
|
|
US8613951B2
(en)
*
|
2008-06-16 |
2013-12-24 |
Bind Therapeutics, Inc. |
Therapeutic polymeric nanoparticles with mTor inhibitors and methods of making and using same
|
|
AU2009266940A1
(en)
*
|
2008-07-01 |
2010-01-07 |
Emory University |
Synergistic induction of humoral and cellular immunity by combinatorial activation of toll-like receptors
|
|
CA2733147A1
(en)
|
2008-08-06 |
2010-02-11 |
Novartis Ag |
Microparticles for use in immunogenic compositions
|
|
WO2010018130A1
(en)
|
2008-08-11 |
2010-02-18 |
Smithkline Beecham Corporation |
Purine derivatives for use in the treatment of allergic, inflammatory and infectious diseases
|
|
UA103195C2
(uk)
|
2008-08-11 |
2013-09-25 |
Глаксосмитклайн Ллк |
Похідні пурину для застосування у лікуванні алергій, запальних та інфекційних захворювань
|
|
WO2010018132A1
(en)
|
2008-08-11 |
2010-02-18 |
Smithkline Beecham Corporation |
Compounds
|
|
JP2011530562A
(ja)
|
2008-08-11 |
2011-12-22 |
グラクソスミスクライン エルエルシー |
アレルギー性、炎症性及び感染性疾患治療用のプリン誘導体
|
|
US8323696B2
(en)
*
|
2008-08-29 |
2012-12-04 |
Ecole Polytechnique Federale De Lausanne |
Nanoparticles for immunotherapy
|
|
US8889635B2
(en)
|
2008-09-30 |
2014-11-18 |
The Regents Of The University Of Michigan |
Dendrimer conjugates
|
|
US8277812B2
(en)
|
2008-10-12 |
2012-10-02 |
Massachusetts Institute Of Technology |
Immunonanotherapeutics that provide IgG humoral response without T-cell antigen
|
|
US8343497B2
(en)
|
2008-10-12 |
2013-01-01 |
The Brigham And Women's Hospital, Inc. |
Targeting of antigen presenting cells with immunonanotherapeutics
|
|
US8343498B2
(en)
|
2008-10-12 |
2013-01-01 |
Massachusetts Institute Of Technology |
Adjuvant incorporation in immunonanotherapeutics
|
|
US8591905B2
(en)
|
2008-10-12 |
2013-11-26 |
The Brigham And Women's Hospital, Inc. |
Nicotine immunonanotherapeutics
|
|
AU2010232512B2
(en)
|
2009-04-01 |
2013-07-18 |
University Of Miami |
Vaccine compositions and methods of use thereof
|
|
CA2759332A1
(en)
|
2009-04-21 |
2010-10-28 |
Selecta Biosciences, Inc. |
Immunonanotherapeutics providing a th1-biased response
|
|
JP5738278B2
(ja)
|
2009-05-01 |
2015-06-24 |
キアジェン ゲイサーズバーグ インコーポレイテッド |
試料中のｒｎａスプライシング形態を検出するための非標的増幅法
|
|
EA022699B1
(ru)
|
2009-05-27 |
2016-02-29 |
Селекта Байосайенсиз, Инк. |
НАЦЕЛЕННЫЕ СИНТЕТИЧЕСКИЕ НАНОНОСИТЕЛИ С pH-ЧУВСТВИТЕЛЬНЫМ ВЫСВОБОЖДЕНИЕМ ИММУНОМОДУЛИРУЮЩИХ СРЕДСТВ
|
|
US20120164189A1
(en)
|
2009-07-07 |
2012-06-28 |
Balu-Iyer Sathy V |
Lipidic Compositions for Induction of Immune Tolerance
|
|
WO2011031298A1
(en)
*
|
2009-08-26 |
2011-03-17 |
Selecta Biosciences, Inc. |
Compositions that induce t cell help
|
|
JP5965844B2
(ja)
|
2009-12-15 |
2016-08-10 |
バインド セラピューティックス インコーポレイテッド |
高いガラス転移温度または高分子量のコポリマーを有する治療用ポリマーナノ粒子組成物
|
|
WO2011085231A2
(en)
|
2010-01-08 |
2011-07-14 |
Selecta Biosciences, Inc. |
Synthetic virus-like particles conjugated to human papillomavirus capsid peptides for use as vaccines
|
|
US20110229556A1
(en)
|
2010-03-19 |
2011-09-22 |
Massachusetts Institute Of Technology |
Lipid-coated polymer particles for immune stimulation
|
|
US20110272836A1
(en)
|
2010-04-12 |
2011-11-10 |
Selecta Biosciences, Inc. |
Eccentric vessels
|
|
US20110262491A1
(en)
|
2010-04-12 |
2011-10-27 |
Selecta Biosciences, Inc. |
Emulsions and methods of making nanocarriers
|
|
CN106177940A
(zh)
|
2010-05-26 |
2016-12-07 |
西莱克塔生物科技公司 |
含有佐剂的合成纳米载体的剂量选择
|
|
US20120058153A1
(en)
|
2010-08-20 |
2012-03-08 |
Selecta Biosciences, Inc. |
Synthetic nanocarrier vaccines comprising proteins obtained or derived from human influenza a virus hemagglutinin
|
|
WO2012027365A2
(en)
|
2010-08-23 |
2012-03-01 |
Selecta Biosciences, Inc. |
Targeted multi-epitope dosage forms for induction of an immune response to antigens
|
|
US9994443B2
(en)
|
2010-11-05 |
2018-06-12 |
Selecta Biosciences, Inc. |
Modified nicotinic compounds and related methods
|
|
WO2012092552A1
(en)
|
2010-12-30 |
2012-07-05 |
Selecta Biosciences, Inc. |
Synthetic nanocarriers with reactive groups that release biologically active agents
|
|
CA2830948A1
(en)
|
2011-03-25 |
2012-10-04 |
Selecta Biosciences, Inc. |
Osmotic mediated release synthetic nanocarriers
|
|
AU2012249553A1
(en)
|
2011-04-29 |
2013-10-24 |
Selecta Biociences, Inc. |
Tolerogenic synthetic nanocarriers for allergy therapy
|
|
KR20140050698A
(ko)
|
2011-07-29 |
2014-04-29 |
셀렉타 바이오사이언시즈, 인크. |
체액성 및 세포독성 t 림프구(ctl) 면역 반응을 발생시키는 합성 나노운반체
|
|
WO2013036303A2
(en)
|
2011-09-06 |
2013-03-14 |
Selecta Biosciences, Inc. |
Induced tolerogenic dendritic cells to reduce systemic inflammatory cytokines
|
|
MX2015015231A
(es)
|
2013-05-03 |
2016-07-06 |
Selecta Biosciences Inc |
Métodos y composiciones para mejorar las células t reguladoras de cd4+.
|
|
KR102631173B1
(ko)
|
2013-06-04 |
2024-01-31 |
셀렉타 바이오사이언시즈, 인크. |
비-면역억제성 항원 특이적 면역요법제의 반복 투여
|
|
US20160220501A1
(en)
|
2015-02-03 |
2016-08-04 |
Selecta Biosciences, Inc. |
Tolerogenic synthetic nanocarriers to reduce immune responses to therapeutic proteins
|
|
US20150359865A1
(en)
|
2014-06-17 |
2015-12-17 |
Selecta Biosciences, Inc. |
Tolerogenic synthetic nanocarriers for t-cell-mediated autoimmune disease
|
|
AU2015279738A1
(en)
|
2014-06-25 |
2016-12-22 |
Selecta Biosciences, Inc. |
Methods and compositions for treatment with synthetic nanocarriers and immune checkpoint inhibitors
|
|
IL292575A
(en)
|
2014-09-07 |
2022-06-01 |
Selecta Biosciences Inc |
Methods and preparations for weakening immune responses by modulating gene expression in an antiviral transfer system
|
|
CA2966850C
(en)
|
2014-11-05 |
2024-03-26 |
Selecta Biosciences, Inc. |
Methods and compositions related to the use of low hlb surfactants in the production of synthetic nanocarriers comprising a rapalog
|