JP2012507270A5 - - Google Patents
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- Publication number
- JP2012507270A5 JP2012507270A5 JP2011533718A JP2011533718A JP2012507270A5 JP 2012507270 A5 JP2012507270 A5 JP 2012507270A5 JP 2011533718 A JP2011533718 A JP 2011533718A JP 2011533718 A JP2011533718 A JP 2011533718A JP 2012507270 A5 JP2012507270 A5 JP 2012507270A5
- Authority
- JP
- Japan
- Prior art keywords
- rad35
- bioreactor
- cells
- perfusion system
- particles
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000000034 method Methods 0.000 claims 7
- 230000010412 perfusion Effects 0.000 claims 7
- 239000002245 particle Substances 0.000 claims 6
- 241000700605 Viruses Species 0.000 claims 3
- 238000012258 culturing Methods 0.000 claims 2
- 241000701124 Human adenovirus 35 Species 0.000 claims 1
- 239000001963 growth medium Substances 0.000 claims 1
- 208000015181 infectious disease Diseases 0.000 claims 1
- 230000002458 infectious effect Effects 0.000 claims 1
- 150000007523 nucleic acids Chemical class 0.000 claims 1
- 102000039446 nucleic acids Human genes 0.000 claims 1
- 108020004707 nucleic acids Proteins 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- 239000000725 suspension Substances 0.000 claims 1
- 241000701161 unidentified adenovirus Species 0.000 claims 1
- 230000003612 virological effect Effects 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US19812208P | 2008-11-03 | 2008-11-03 | |
| EP08168181 | 2008-11-03 | ||
| EP08168181.9 | 2008-11-03 | ||
| US61/198,122 | 2008-11-03 | ||
| PCT/EP2009/064265 WO2010060719A1 (en) | 2008-11-03 | 2009-10-29 | Method for the production of adenoviral vectors |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012507270A JP2012507270A (ja) | 2012-03-29 |
| JP2012507270A5 true JP2012507270A5 (https=) | 2012-12-13 |
| JP5770633B2 JP5770633B2 (ja) | 2015-08-26 |
Family
ID=40344776
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011533718A Expired - Fee Related JP5770633B2 (ja) | 2008-11-03 | 2009-10-29 | アデノウイルスベクターの産生方法 |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US10041049B2 (https=) |
| EP (1) | EP2350268B1 (https=) |
| JP (1) | JP5770633B2 (https=) |
| KR (1) | KR101504392B1 (https=) |
| CN (1) | CN102203242B (https=) |
| AU (1) | AU2009319254B2 (https=) |
| BR (1) | BRPI0921651A2 (https=) |
| CA (1) | CA2742474C (https=) |
| DK (1) | DK2350268T3 (https=) |
| EA (1) | EA019928B1 (https=) |
| ES (1) | ES2532015T3 (https=) |
| MX (1) | MX2011004292A (https=) |
| NZ (1) | NZ593235A (https=) |
| PL (1) | PL2350268T3 (https=) |
| WO (1) | WO2010060719A1 (https=) |
Families Citing this family (55)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102203242B (zh) | 2008-11-03 | 2013-06-12 | 克鲁塞尔荷兰公司 | 产生腺病毒载体的方法 |
| CN102575233B (zh) | 2009-10-15 | 2014-07-16 | 克鲁塞尔荷兰公司 | 从高细胞密度培养物纯化腺病毒的方法 |
| EA028623B1 (ru) | 2009-10-15 | 2017-12-29 | Янссен Вэксинс Энд Превеншн Б.В. | Способ очистки аденовирусных частиц |
| MX2012007936A (es) * | 2010-02-15 | 2012-11-22 | Crucell Holland Bv | Metodo para la produccion de vectores adenovirales del serotipo 26 del adenovirus. |
| EP2618838A1 (en) | 2010-09-20 | 2013-07-31 | Crucell Holland B.V. | Therapeutic vaccination against active tuberculosis |
| MX354752B (es) | 2010-09-27 | 2018-03-20 | Janssen Vaccines & Prevention Bv | Regimen de vacunacion de sensibilizacion y refuerzo heterologo contra malaria. |
| US8845902B2 (en) | 2011-02-10 | 2014-09-30 | Crucell Holland B.V. | Pneumatic alternating pressure membrane cell separation system |
| WO2013074501A1 (en) | 2011-11-14 | 2013-05-23 | Crucell Holland B.V. | Heterologous prime-boost immunization using measles virus-based vaccines |
| JP5770952B2 (ja) | 2012-03-12 | 2015-08-26 | クルセル ホランド ベー ヴェー | 改変末端を有する組換えアデノウイルスのバッチ |
| US8932607B2 (en) | 2012-03-12 | 2015-01-13 | Crucell Holland B.V. | Batches of recombinant adenovirus with altered terminal ends |
| US9119813B2 (en) | 2012-03-22 | 2015-09-01 | Crucell Holland B.V. | Vaccine against RSV |
| EA026504B1 (ru) | 2012-03-22 | 2017-04-28 | Круселл Холланд Б.В. | Вакцина против rsv |
| JP6469081B2 (ja) | 2013-04-25 | 2019-02-13 | ヤンセン ファッシンズ アンド プリベンション ベーフェーＪａｎｓｓｅｎ Ｖａｃｃｉｎｅｓ ＆ Ｐｒｅｖｅｎｔｉｏｎ Ｂ．Ｖ． | 安定化された可溶性融合前ｒｓｖｆポリペプチド |
| MY171210A (en) | 2013-06-17 | 2019-10-02 | Janssen Vaccines & Prevention Bv | Stabilized soluble pre-fusion rsv f polypeptides |
| US10392603B2 (en) * | 2013-08-30 | 2019-08-27 | The Chemo-Sero-Therapeutic Research Institute | Method of viral purification |
| WO2015148704A1 (en) | 2014-03-25 | 2015-10-01 | Terumo Bct, Inc. | Passive replacement of media |
| HUE040440T2 (hu) | 2014-11-04 | 2019-03-28 | Janssen Vaccines & Prevention Bv | Terápiás HPV16-oltóanyagok |
| WO2017004592A1 (en) | 2015-07-02 | 2017-01-05 | Terumo Bct, Inc. | Cell growth with mechanical stimuli |
| CN107847581B (zh) | 2015-07-07 | 2022-03-22 | 扬森疫苗与预防公司 | 稳定化的可溶性融合前rsv f多肽 |
| ES2839880T3 (es) | 2015-07-07 | 2021-07-06 | Janssen Vaccines & Prevention Bv | Vacuna contra el VRS |
| US9663766B2 (en) | 2015-07-24 | 2017-05-30 | Bio-Rad Laboratories, Inc. | Methods for purifying adenovirus vectors |
| KR20180042295A (ko) | 2015-08-20 | 2018-04-25 | 얀센 백신스 앤드 프리벤션 비.브이. | 치료용 hpv18 백신 |
| KR102500970B1 (ko) | 2016-04-05 | 2023-02-17 | 얀센 백신스 앤드 프리벤션 비.브이. | Rsv에 대한 백신 |
| PH12022552125A1 (en) | 2016-04-05 | 2023-04-12 | Janssen Vaccines & Prevention Bv | Stabilized soluble pre-fusion rsv f proteins |
| WO2017180724A1 (en) * | 2016-04-12 | 2017-10-19 | Artemis Biosystems, Inc. | Perfusion filtration systems |
| EP3452087A1 (en) | 2016-05-02 | 2019-03-13 | Janssen Vaccines & Prevention B.V. | Therapeutic hpv vaccine combinations |
| JP7034949B2 (ja) | 2016-05-25 | 2022-03-14 | テルモ ビーシーティー、インコーポレーテッド | 細胞の増殖 |
| IL264119B2 (en) | 2016-05-30 | 2023-04-01 | Janssen Vaccines Prevention B V | f proteins of rsv are stabilized before fusion |
| US11104874B2 (en) | 2016-06-07 | 2021-08-31 | Terumo Bct, Inc. | Coating a bioreactor |
| US11685883B2 (en) | 2016-06-07 | 2023-06-27 | Terumo Bct, Inc. | Methods and systems for coating a cell growth surface |
| US10744196B2 (en) | 2016-07-14 | 2020-08-18 | Janssen Vaccines & Prevention B.V. | HPV vaccines |
| CN117247899A (zh) | 2017-03-31 | 2023-12-19 | 泰尔茂比司特公司 | 细胞扩增 |
| US11229692B2 (en) | 2017-05-17 | 2022-01-25 | Janssen Vaccines & Prevention B.V. | Methods and compositions for inducing protective immunity against RSV infection |
| WO2019053109A1 (en) | 2017-09-15 | 2019-03-21 | Janssen Vaccines & Prevention B.V. | METHOD FOR SAFE INDUCTION OF IMMUNITY AGAINST RSV |
| WO2019086450A1 (en) | 2017-10-31 | 2019-05-09 | Janssen Vaccines & Prevention B.V. | Adenovirus and uses thereof |
| MA50502A (fr) | 2017-10-31 | 2020-09-09 | Janssen Vaccines & Prevention Bv | Adénovirus et utilisations associées |
| BR112020008435A2 (pt) | 2017-10-31 | 2020-11-17 | Janssen Vaccines & Prevention B.V. | vetores de adenovírus e seus usos |
| WO2019086466A1 (en) | 2017-10-31 | 2019-05-09 | Janssen Vaccines & Prevention B.V. | Adenovirus and uses thereof |
| KR20250111232A (ko) * | 2017-12-11 | 2025-07-22 | 암젠 인크 | 이중특이적 항체 생성물의 연속 제조 공정 |
| CN110317832B (zh) | 2018-03-28 | 2022-07-05 | 西比曼生物科技（香港）有限公司 | Gmp级规模化制备重组慢病毒载体的纯化制剂的方法 |
| CN110317791A (zh) | 2018-03-29 | 2019-10-11 | 西比曼生物科技（香港）有限公司 | Gmp级无血清悬浮细胞大规模生产慢病毒的方法 |
| US12060583B2 (en) | 2018-04-24 | 2024-08-13 | Merck Sharp & Dohme Llc | Scalable chromatography process for purification of human cytomegalovirus |
| JP2022513025A (ja) | 2018-11-13 | 2022-02-07 | ヤンセン ファッシンズ アンド プリベンション ベーフェー | 安定化された融合前ｒｓｖ ｆタンパク質 |
| WO2021003188A1 (en) * | 2019-07-01 | 2021-01-07 | Ology Bioservices, Inc. | Method for cultivation of adherent cells in a multiparallel bioreactor |
| TW202204380A (zh) | 2020-01-31 | 2022-02-01 | 美商詹森藥物公司 | 用於預防及治療冠狀病毒感染之組合物及方法－sars-cov-2疫苗 |
| GB202013940D0 (en) | 2020-09-04 | 2020-10-21 | Synpromics Ltd | Regulatory nucleic acid sequences |
| AU2021358957A1 (en) | 2020-10-07 | 2023-06-08 | AskBio Inc. | Therapeutic adeno-associated virus delivery of fukutin related protein (fkrp) for treating dystroglycanopathy. disorders including limb girdle 21 |
| KR20230165275A (ko) | 2021-04-01 | 2023-12-05 | 얀센 백신스 앤드 프리벤션 비.브이. | 안정화된 융합 전 piv3 f 단백질 |
| WO2023020939A1 (en) | 2021-08-17 | 2023-02-23 | Janssen Pharmaceuticals, Inc. | Sars-cov-2 vaccines |
| WO2023111725A1 (en) | 2021-12-14 | 2023-06-22 | Janssen Pharmaceuticals, Inc. | Sars-cov-2 vaccines |
| EP4448802A1 (en) | 2021-12-16 | 2024-10-23 | Janssen Vaccines & Prevention B.V. | Stabilized pre-fusion hmpv fusion proteins |
| WO2024061753A1 (en) | 2022-09-23 | 2024-03-28 | Janssen Vaccines & Prevention B.V. | Stabilized trimeric class i fusion proteins |
| WO2024061757A1 (en) | 2022-09-23 | 2024-03-28 | Janssen Vaccines & Prevention B.V. | Pre-fusion human piv1 f proteins |
| CN120344553A (zh) | 2022-10-06 | 2025-07-18 | Msd国际商务股份有限公司 | 稳定的融合前piv3 f蛋白 |
| WO2024190895A1 (ja) | 2023-03-15 | 2024-09-19 | 東レ株式会社 | フィルターユニット、精製装置及び精製液の製造方法 |
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| CN102203242B (zh) | 2008-11-03 | 2013-06-12 | 克鲁塞尔荷兰公司 | 产生腺病毒载体的方法 |
| AP3140A (en) | 2009-07-16 | 2015-02-28 | Crucell Holland Bv | Production of polio virus at high titers for vaccine production |
| CN102575233B (zh) | 2009-10-15 | 2014-07-16 | 克鲁塞尔荷兰公司 | 从高细胞密度培养物纯化腺病毒的方法 |
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-
2009
- 2009-10-29 CN CN2009801438951A patent/CN102203242B/zh not_active Expired - Fee Related
- 2009-10-29 DK DK09744140.6T patent/DK2350268T3/en active
- 2009-10-29 KR KR1020117010793A patent/KR101504392B1/ko not_active Expired - Fee Related
- 2009-10-29 AU AU2009319254A patent/AU2009319254B2/en not_active Ceased
- 2009-10-29 US US13/126,978 patent/US10041049B2/en active Active
- 2009-10-29 CA CA2742474A patent/CA2742474C/en active Active
- 2009-10-29 NZ NZ593235A patent/NZ593235A/xx not_active IP Right Cessation
- 2009-10-29 MX MX2011004292A patent/MX2011004292A/es active IP Right Grant
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