JP2014521353A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2014521353A5 JP2014521353A5 JP2014524110A JP2014524110A JP2014521353A5 JP 2014521353 A5 JP2014521353 A5 JP 2014521353A5 JP 2014524110 A JP2014524110 A JP 2014524110A JP 2014524110 A JP2014524110 A JP 2014524110A JP 2014521353 A5 JP2014521353 A5 JP 2014521353A5
- Authority
- JP
- Japan
- Prior art keywords
- vaccinia virus
- present
- culture
- hela cells
- roller bottle
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161515724P | 2011-08-05 | 2011-08-05 | |
| US61/515,724 | 2011-08-05 | ||
| PCT/US2012/049550 WO2013022764A1 (en) | 2011-08-05 | 2012-08-03 | Methods and compositions for production of vaccina virus |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014521353A JP2014521353A (ja) | 2014-08-28 |
| JP2014521353A5 true JP2014521353A5 (https=) | 2016-10-20 |
| JP6243333B2 JP6243333B2 (ja) | 2017-12-06 |
Family
ID=46650950
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014524110A Active JP6243333B2 (ja) | 2011-08-05 | 2012-08-03 | ワクシニアウィルスの生成のための方法および組成物 |
Country Status (12)
| Country | Link |
|---|---|
| US (3) | US9719105B2 (https=) |
| EP (1) | EP2739293B1 (https=) |
| JP (1) | JP6243333B2 (https=) |
| KR (1) | KR102022952B1 (https=) |
| CN (1) | CN103732236B (https=) |
| AU (1) | AU2012294606B2 (https=) |
| BR (1) | BR112014000787B1 (https=) |
| CA (1) | CA2841831C (https=) |
| DK (1) | DK2739293T3 (https=) |
| ES (1) | ES2813413T3 (https=) |
| PL (1) | PL2739293T3 (https=) |
| WO (1) | WO2013022764A1 (https=) |
Families Citing this family (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK3169341T3 (da) | 2014-07-16 | 2019-08-05 | Transgene Sa | Onkolytisk virus til ekspression af immun-checkpoint-modulatorer |
| ES3011733T3 (en) | 2015-02-13 | 2025-04-08 | Transgene | Immunotherapeutic vaccine and antibody combination therapy |
| WO2016131945A1 (en) | 2015-02-20 | 2016-08-25 | Transgene Sa | Combination product with autophagy modulator |
| CN108025056B (zh) | 2015-06-19 | 2022-01-14 | 新罗杰股份有限公司 | 用于病毒栓塞的组合物和方法 |
| CN106676071B (zh) * | 2015-11-06 | 2019-07-19 | 天士力创世杰（天津）生物制药有限公司 | HeLa-F细胞及其用途 |
| CA3023022A1 (en) | 2016-05-04 | 2017-11-09 | Transgene Sa | Combination therapy with cpg tlr9 ligand |
| US20190328869A1 (en) | 2016-10-10 | 2019-10-31 | Transgene Sa | Immunotherapeutic product and mdsc modulator combination therapy |
| WO2018091680A1 (en) | 2016-11-18 | 2018-05-24 | Transgene Sa | Cowpox-based oncolytic vectors |
| KR20190097240A (ko) | 2016-12-28 | 2019-08-20 | 트랜스진 에스.에이. | 종양용해성 바이러스 및 치료 분자 |
| KR20240132482A (ko) | 2017-04-21 | 2024-09-03 | 신라젠(주) | 항암 백시니아 바이러스와 관문 저해제 병용 요법 |
| KR20240113607A (ko) | 2017-06-21 | 2024-07-22 | 트랜스진 | 개인 맞춤형 백신 |
| WO2019020543A1 (en) | 2017-07-28 | 2019-01-31 | Transgene Sa | ONCOLYTIC VIRUSES EXPRESSING AGENTS TARGETING METABOLIC IMMUNE MODULATORS |
| EP3973973A1 (en) | 2017-10-31 | 2022-03-30 | KaliVir Immunotherapeutics, Inc. | Platform oncolytic vector for systemic delivery |
| WO2020011754A1 (en) | 2018-07-09 | 2020-01-16 | Transgene | Chimeric vaccinia viruses |
| EP3617230A1 (en) | 2018-09-03 | 2020-03-04 | BioInvent International AB | Novel antibodies and nucleotide sequences, and uses thereof |
| JP7625519B2 (ja) * | 2018-11-21 | 2025-02-03 | カリヴィル イムノセラピューティクス， インコーポレイテッド | ウイルスの製造 |
| JP7625521B2 (ja) | 2018-12-28 | 2025-02-03 | トランスジーン | ｍ２欠陥ポックスウイルス |
| KR102228267B1 (ko) | 2019-01-25 | 2021-03-17 | 바이로큐어 주식회사 | Bhk-21 세포를 이용한 바이러스 생산방법 |
| CN112143693B (zh) * | 2019-06-28 | 2024-12-27 | 杭州康万达医药科技有限公司 | 一种生产病毒的方法及收获液组合物 |
| EP3842065A1 (en) | 2019-12-23 | 2021-06-30 | Transgene | Process for designing a recombinant poxvirus for a therapeutic vaccine |
| KR20230027070A (ko) * | 2020-06-22 | 2023-02-27 | 코오롱생명과학 주식회사 | 부유세포를 이용한 백시니아 바이러스의 대량 생산 방법 |
| TW202217002A (zh) | 2020-07-13 | 2022-05-01 | 法商傳斯堅公司 | 免疫抑制之治療 |
| CA3197371A1 (en) | 2020-11-19 | 2022-05-27 | Kalivir Immunotherapeutics, Inc. | Oncolytic immunotherapy by tumor micro-environment remodeling |
| WO2022148736A1 (en) | 2021-01-05 | 2022-07-14 | Transgene | Vectorization of muc1 t cell engager |
| EP4329786A4 (en) | 2021-04-30 | 2024-12-11 | KaliVir Immunotherapeutics, Inc. | Oncolytic viruses for modified mhc expression |
| WO2023025899A2 (en) | 2021-08-26 | 2023-03-02 | Transgene | Delivery system for targeting genes of the interferon pathway |
| TW202321458A (zh) | 2021-09-22 | 2023-06-01 | 瑞典商生物創新國際公司 | 新穎抗體組合及其用途 |
| GB2614309A (en) | 2021-12-24 | 2023-07-05 | Stratosvir Ltd | Improved vaccinia virus vectors |
| CN114395538A (zh) * | 2022-01-19 | 2022-04-26 | 和元生物技术（上海）股份有限公司 | 一种促进重组病毒载体向细胞外分泌的方法 |
| WO2023213764A1 (en) | 2022-05-02 | 2023-11-09 | Transgene | Fusion polypeptide comprising an anti-pd-l1 sdab and a member of the tnfsf |
| WO2023213763A1 (en) | 2022-05-02 | 2023-11-09 | Transgene | Poxvirus encoding a binding agent comprising an anti- pd-l1 sdab |
| KR20250034101A (ko) | 2022-07-01 | 2025-03-10 | 트랜스진 | 계면활성제-단백질-d 및 tnfsf의 구성원을 포함하는 융합 단백질 |
| CA3261778A1 (en) | 2022-08-18 | 2024-02-22 | Transgene | CHIMERIC POXVIRUSES |
| EP4677076A1 (en) * | 2023-03-10 | 2026-01-14 | Bavarian Nordic A/S | Methods of isolating poxviruses from avian cell cultures |
| WO2026041811A1 (en) | 2024-08-23 | 2026-02-26 | Transgene | Recombinant poxvirus and method for regulating the expression of toxic conditional gene products of said recombinant poxvirus in a producing cell |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6267965B1 (en) | 1981-12-24 | 2001-07-31 | Virogenetics Corporation | Recombinant poxvirus—cytomegalovirus compositions and uses |
| UA68327C2 (en) * | 1995-07-04 | 2004-08-16 | Gsf Forschungszentrum Fur Unwe | A recombinant mva virus, an isolated eukaryotic cell, infected with recombinant mva virus, a method for production in vitro of polypeptides with use of said cell, a method for production in vitro of virus parts (variants), vaccine containing the recombinant mva virus, a method for immunization of animals |
| PL212047B1 (pl) * | 2000-11-23 | 2012-08-31 | Bavarian Nordic As | Zmodyfikowany wirus krowianki szczepu Ankara MVA-BN i jego pochodna, genom i zawierające je kompozycja farmaceutyczna, zwłaszcza szczepionka oraz ich zastosowania |
| US7445924B2 (en) * | 2000-11-23 | 2008-11-04 | Bavarian Nordic A/S | Modified Vaccinia Ankara virus variant and cultivation method |
| EP2269619A1 (en) | 2002-08-12 | 2011-01-05 | Jennerex Biotherapeutics ULC | Methods and compositions concerning poxviruses and cancer |
| DK1869171T4 (en) * | 2005-04-11 | 2016-01-18 | Crucell Holland Bv | Virus cleaning using ultrafiltration |
| KR101772375B1 (ko) * | 2005-09-07 | 2017-08-29 | 신라젠(주) | Ｇｍ-ｃｓｆ를 발현하는 폭스바이러스를 사용한 전이성 및/또는 전신 파종성 암의 전신 치료법 |
| EP2055311B1 (en) * | 2006-08-07 | 2017-06-21 | The Chemo-Sero-Therapeutic Research Institute | Process for preparing live smallpox vaccine |
| KR20080084528A (ko) | 2007-03-15 | 2008-09-19 | 제네렉스 바이오테라퓨틱스 인크. | 종양살상형 백시니아 바이러스 암 치료 |
| US8003364B2 (en) * | 2007-05-14 | 2011-08-23 | Bavarian Nordic A/S | Purification of vaccinia viruses using hydrophobic interaction chromatography |
| WO2009048769A2 (en) * | 2007-10-10 | 2009-04-16 | Kirin Pharma Kabushiki Kaisha | Vaccinia virus h3l and b5r specific monoclonal antibodies and methods of making and using same |
| EP2085092A1 (en) * | 2008-01-29 | 2009-08-05 | Bayer Schering Pharma Aktiengesellschaft | Attenuated oncolytic paramyxoviruses encoding avian cytokines |
| EP2459701A1 (en) | 2009-07-28 | 2012-06-06 | Corning Inc. | Synthetic microcarriers for culturing cells |
| BR112012005774B8 (pt) * | 2009-09-14 | 2023-02-14 | Jennerex Inc | uso de um inibidor de quinase antiangiogênico no tratamento de câncer |
-
2012
- 2012-08-03 EP EP12746243.0A patent/EP2739293B1/en active Active
- 2012-08-03 ES ES12746243T patent/ES2813413T3/es active Active
- 2012-08-03 AU AU2012294606A patent/AU2012294606B2/en not_active Ceased
- 2012-08-03 WO PCT/US2012/049550 patent/WO2013022764A1/en not_active Ceased
- 2012-08-03 PL PL12746243T patent/PL2739293T3/pl unknown
- 2012-08-03 US US14/236,982 patent/US9719105B2/en active Active
- 2012-08-03 JP JP2014524110A patent/JP6243333B2/ja active Active
- 2012-08-03 KR KR1020147005901A patent/KR102022952B1/ko active Active
- 2012-08-03 DK DK12746243.0T patent/DK2739293T3/da active
- 2012-08-03 BR BR112014000787-0A patent/BR112014000787B1/pt active IP Right Grant
- 2012-08-03 CA CA2841831A patent/CA2841831C/en active Active
- 2012-08-03 CN CN201280038029.8A patent/CN103732236B/zh active Active
-
2017
- 2017-06-27 US US15/634,765 patent/US10202581B2/en active Active
-
2019
- 2019-02-07 US US16/270,585 patent/US10767166B2/en active Active
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2014521353A5 (https=) | ||
| US8778675B2 (en) | Immortalized avian cell lines and use thereof | |
| JP2019201661A5 (https=) | ||
| JP6243333B2 (ja) | ワクシニアウィルスの生成のための方法および組成物 | |
| JP2012507270A5 (https=) | ||
| JP2016105737A5 (https=) | ||
| RU2019139064A (ru) | Композиции и способы для лечения цитомегаловируса | |
| WO2020076820A3 (en) | Compositions and methods for preparing viral vectors | |
| JP2013507935A5 (https=) | ||
| JP2009528843A5 (https=) | ||
| CN104087613B (zh) | 基于aav‑itr的基因表达微载体及其构建方法和应用 | |
| Irie et al. | Sendai virus C proteins regulate viral genome and antigenome synthesis to dictate the negative genome polarity | |
| JP2025169249A5 (https=) | ||
| WO2023035372A1 (zh) | 一种有限自我复制mRNA分子系统、制备方法及应用 | |
| Zhang et al. | Insights into leghorn male hepatocellular cells response to fowl adenovirus serotype 4 infection by transcriptome analysis | |
| Galante et al. | Identification and characterization of Orf viruses isolated from sheep and goats in Southern Italy | |
| CN111484972A (zh) | 一种从儿童包皮培养获得具备多向分化潜能和免疫调节功能间充质干细胞的方法 | |
| Bratt et al. | Genetics and paragenetic phenomena of paramyxoviruses | |
| WO2006038742A1 (ja) | 組み換えウイルスおよびその用途 | |
| Pelz et al. | Production of antiviral “OP7 chimera” defective interfering particles free of infectious virus | |
| CN111662883A (zh) | 一种制备及纯化溶瘤病毒的方法及重组溶瘤弹状病毒 | |
| Saghi et al. | Biochemical characterization of temperature-sensitive rabies virus mutants | |
| JPWO2023066874A5 (https=) | ||
| CN116162599B (zh) | GSK3β在增强塞内卡病毒复制用于制备疫苗中的用途 | |
| JP2013529913A5 (https=) |