JP2013529913A5 - - Google Patents
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- Publication number
- JP2013529913A5 JP2013529913A5 JP2013512943A JP2013512943A JP2013529913A5 JP 2013529913 A5 JP2013529913 A5 JP 2013529913A5 JP 2013512943 A JP2013512943 A JP 2013512943A JP 2013512943 A JP2013512943 A JP 2013512943A JP 2013529913 A5 JP2013529913 A5 JP 2013529913A5
- Authority
- JP
- Japan
- Prior art keywords
- virus
- protein
- helper virus
- helper
- protease
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 241000700605 Viruses Species 0.000 claims 35
- 108090000623 proteins and genes Proteins 0.000 claims 25
- 102000004169 proteins and genes Human genes 0.000 claims 25
- 238000000034 method Methods 0.000 claims 17
- 239000002245 particle Substances 0.000 claims 14
- 239000004365 Protease Substances 0.000 claims 8
- 108091005804 Peptidases Proteins 0.000 claims 7
- 102100037486 Reverse transcriptase/ribonuclease H Human genes 0.000 claims 7
- 235000019419 proteases Nutrition 0.000 claims 7
- 101150076840 PolI gene Proteins 0.000 claims 4
- 238000012217 deletion Methods 0.000 claims 4
- 230000037430 deletion Effects 0.000 claims 4
- 125000001429 N-terminal alpha-amino-acid group Chemical group 0.000 claims 3
- 108010067372 Pancreatic elastase Proteins 0.000 claims 3
- 102000016387 Pancreatic elastase Human genes 0.000 claims 3
- 108090000631 Trypsin Proteins 0.000 claims 3
- 102000004142 Trypsin Human genes 0.000 claims 3
- 150000001413 amino acids Chemical class 0.000 claims 3
- 238000012986 modification Methods 0.000 claims 3
- 230000004048 modification Effects 0.000 claims 3
- 239000012588 trypsin Substances 0.000 claims 3
- 238000003776 cleavage reaction Methods 0.000 claims 2
- 230000001086 cytosolic effect Effects 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- 230000007017 scission Effects 0.000 claims 2
- 241000712461 unidentified influenza virus Species 0.000 claims 2
- 108090000317 Chymotrypsin Proteins 0.000 claims 1
- 241000711573 Coronaviridae Species 0.000 claims 1
- 101150039660 HA gene Proteins 0.000 claims 1
- 102000014150 Interferons Human genes 0.000 claims 1
- 108010050904 Interferons Proteins 0.000 claims 1
- 101150080862 NA gene Proteins 0.000 claims 1
- 101150076514 NS gene Proteins 0.000 claims 1
- 101150033828 NS1 gene Proteins 0.000 claims 1
- 108090000526 Papain Proteins 0.000 claims 1
- 102000017143 RNA Polymerase I Human genes 0.000 claims 1
- 108010013845 RNA Polymerase I Proteins 0.000 claims 1
- 102000009572 RNA Polymerase II Human genes 0.000 claims 1
- 108010009460 RNA Polymerase II Proteins 0.000 claims 1
- 125000003275 alpha amino acid group Chemical group 0.000 claims 1
- 230000003321 amplification Effects 0.000 claims 1
- 238000004458 analytical method Methods 0.000 claims 1
- 230000000890 antigenic effect Effects 0.000 claims 1
- 230000002238 attenuated effect Effects 0.000 claims 1
- 229960002376 chymotrypsin Drugs 0.000 claims 1
- 238000012258 culturing Methods 0.000 claims 1
- 230000002950 deficient Effects 0.000 claims 1
- 241001493065 dsRNA viruses Species 0.000 claims 1
- 230000000694 effects Effects 0.000 claims 1
- 108010028403 hemagglutinin esterase Proteins 0.000 claims 1
- 229940079322 interferon Drugs 0.000 claims 1
- 238000003199 nucleic acid amplification method Methods 0.000 claims 1
- 150000007523 nucleic acids Chemical class 0.000 claims 1
- 102000039446 nucleic acids Human genes 0.000 claims 1
- 108020004707 nucleic acids Proteins 0.000 claims 1
- 235000019834 papain Nutrition 0.000 claims 1
- 229940055729 papain Drugs 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP10164779 | 2010-06-02 | ||
| EP10164779.0 | 2010-06-02 | ||
| PCT/EP2011/059284 WO2011151470A2 (en) | 2010-06-02 | 2011-06-06 | Novel method for generation of rna virus |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2013529913A JP2013529913A (ja) | 2013-07-25 |
| JP2013529913A5 true JP2013529913A5 (https=) | 2014-07-10 |
Family
ID=44627454
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013512943A Withdrawn JP2013529913A (ja) | 2010-06-02 | 2011-06-06 | Ｒｎａウィルスの作製のための方法及びヘルパーウィルス |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20130183740A1 (https=) |
| EP (1) | EP2576773A2 (https=) |
| JP (1) | JP2013529913A (https=) |
| KR (1) | KR20130115105A (https=) |
| CN (1) | CN103237890A (https=) |
| CA (1) | CA2801268A1 (https=) |
| EA (1) | EA201201620A1 (https=) |
| WO (1) | WO2011151470A2 (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103865923B (zh) * | 2014-01-28 | 2017-04-26 | 中国人民解放军第三0二医院 | 流感病毒为载体的HAdV嵌合疫苗的制备及其应用 |
| CN109097341B (zh) * | 2018-08-28 | 2021-09-24 | 青岛农业大学 | 一种同时表达ha和hef的复制缺陷型重组流感病毒 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2737501B1 (fr) * | 1995-07-31 | 1997-10-24 | Transgene Sa | Nouveaux virus auxiliaires pour la preparation de vecteurs viraux recombinants |
| DE69937999T2 (de) | 1998-06-12 | 2009-01-29 | Avir Green Hills Biotechnology Research Development Trade Ag | Interferon induzierende genetisch veränderte attenuierte viren |
| JP4837827B2 (ja) * | 1998-06-12 | 2011-12-14 | マウント シナイ スクール オブ メディシン | 新規なウイルス増殖方法およびそのためのインターフェロン欠損培養基 |
| US6280977B1 (en) | 1999-03-24 | 2001-08-28 | Gene Therapy Systems | Method for generating transcriptionally active DNA fragments |
| DE122008000035I1 (de) | 1999-04-06 | 2009-05-20 | Wisconsin Alumni Res Found | Rekombinante influenzaviren zur vakzinherstellung und gentherapie |
| ES2278621T5 (es) | 1999-07-14 | 2011-02-02 | Mount Sinai School Of Medicine Of New York University | Reconstrucción in vitro de virus arn segmentados de polaridad negativa. |
| ES2319864T3 (es) | 2000-04-28 | 2009-05-14 | St. Jude Children's Research Hospital | Sistema de transfeccion de adn para la generacion de virus infecciosos de arn de cadena negativa. |
| CA2447450C (en) * | 2001-05-17 | 2011-12-20 | Universiteit Utrecht | Corona-virus-like particles comprising functionally deleted genomes |
| DE10248301A1 (de) * | 2002-10-16 | 2004-04-29 | Philipps-Universität Marburg | Herstellung eines Lebend-Impfstoffes gegen Influenza-Viren |
| EP2295542B1 (en) * | 2004-12-24 | 2013-01-30 | Abbott Biologicals B.V. | Rescue of influenza virus |
| EP2048237A1 (en) * | 2007-10-05 | 2009-04-15 | Avir Green Hills Biotechnology Research Development Trade Ag | Replication deficient Influenza virus for the expression of heterologous sequences |
| EP2045323A1 (en) * | 2007-10-05 | 2009-04-08 | Avir Green Hills Biotechnology Research Development Trade Ag | Linear expression constructs for production of influenza virus particles |
| CN102223895B (zh) * | 2008-11-25 | 2014-11-05 | 巴克斯特保健股份有限公司 | 生产pH稳定的包膜病毒的方法 |
| EP2233568A1 (en) * | 2009-03-19 | 2010-09-29 | Avir Green Hills Biotechnology Research Development Trade AG | Novel method for generation of RNA virus |
| EP2233152A1 (en) * | 2009-03-24 | 2010-09-29 | Avir Green Hills Biotechnology Research Development Trade Ag | High growth reassortant influenza A virus |
| ES2557315T3 (es) * | 2009-07-22 | 2016-01-25 | Baxalta GmbH | Nuevo virus de la gripe |
-
2011
- 2011-06-06 CN CN201180041228XA patent/CN103237890A/zh active Pending
- 2011-06-06 JP JP2013512943A patent/JP2013529913A/ja not_active Withdrawn
- 2011-06-06 EP EP11727412.6A patent/EP2576773A2/en not_active Withdrawn
- 2011-06-06 WO PCT/EP2011/059284 patent/WO2011151470A2/en not_active Ceased
- 2011-06-06 CA CA2801268A patent/CA2801268A1/en not_active Abandoned
- 2011-06-06 KR KR1020127033905A patent/KR20130115105A/ko not_active Withdrawn
- 2011-06-06 EA EA201201620A patent/EA201201620A1/ru unknown
- 2011-06-06 US US13/701,164 patent/US20130183740A1/en not_active Abandoned
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